Childhood immunizations in the United States diphtheria patients die. Without treatment as many as half the patients can die from the disease. Pertussis is a highly contagious disease that is caused by the bacteria "Bordetella pertussis." The bacteria clings to cilia in the lungs and releases a toxin that damages the cilia and causes inflammation in the respiratory tract. Many infants are infected by older siblings or caregivers that don't even know they have the disease. The bacteria is spread through respiratory secretions, often through coughing or sneezing, or just from breathing in the bacteria while around someone who is infected. Unfortunately, the effectiveness of the
Machado–Joseph disease Machado–Joseph disease Machado–Joseph disease (MJD), also known as Machado–Joseph Azorean disease, Machado's disease, Joseph's disease or spinocerebellar ataxia type 3 (SCA3), is a rare autosomal dominantly inherited neurodegenerative disease that causes progressive cerebellar ataxia, which results in a lack of muscle control and coordination of the upper and lower extremities. The symptoms are caused by a genetic mutation that results in an expansion of abnormal "CAG" trinucleotide repeats in the ATXN3 gene that results in an abnormal form of the protein ataxin which causes degeneration of cells in the hindbrain. Some symptoms, such as clumsiness and rigidity, make MJD commonly