Pertussis vaccine more likely the older the child. The whole-cell vaccines should not be used after seven years of age. According to the WHO serious long term neurological problems are not associated with either type. The WHO says that the only contraindication to either whole cell or acellular pertussis vaccines is an anaphylactic reaction to a previous dose of pertussis vaccine, while the US CDC lists encephalopathy not due to another identifiable cause occurring within seven days after a previous dose of pertussis vaccine as a contraindication and recommends those who have had seizures, have a known or suspected neurological disorder, or
Alzheimer's disease biomarkers Alzheimer's disease biomarkers The Alzheimer's disease biomarkers are neurochemical indicators used to assess the risk or presence of the disease. The biomarkers can be used to diagnose Alzheimer's disease (AD) in a very early stage, but they also provide objective and reliable measures of disease progress. It is imperative to diagnose AD disease as soon as possible, because neuropathologic changes of AD precede the symptoms by years. It is well known that beta amyloid (Aβ) is a good indicator of AD disease, which has facilitated doctors to accurately pre-diagnose cases of AD disease. When Aβ peptide is released by proteolytic