Bordetella pertussis whoop. A coughing spell may last a minute or more, producing cyanosis, apnoea, and seizures. However, when not in a coughing fit, the patient does not experience trouble breathing. This is because "B. pertussis" inhibits the immune response, so very little mucus is generated in the lungs. A prolonged cough may be irritating and sometimes a disabling cough may go undiagnosed in adults for many months. Uncertainties of "B. pertussis" and whooping cough as a zoonotic disease have existed since around 1910, but in the 1930s, the bacteria were found to have lost their virulent power when repeatedly spread on
Gaucher's disease May 1994 and has replaced the use of Ceredase. October is National Gaucher's Disease Awareness Month in the United States. Gaucher's disease Gaucher's disease or Gaucher disease () (GD) is a genetic disorder in which glucocerebroside (a sphingolipid, also known as glucosylceramide) accumulates in cells and certain organs. The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the enzyme glucocerebrosidase (also known as glucosylceramidase), which acts on glucocerebroside. When the enzyme is defective, glucocerebroside accumulates, particularly in white blood cells and especially