Pertussis vaccine pertussis" bacteria. Until the beginning of the 1990s it was used as a part of the DTwP vaccine for the immunization of children. It, however, contained pertussis endotoxin (surface lipooligosaccharide) and produced side effects. New acellular pertussis vaccines were developed in the 1980s, which included only a few selected pertussis antigens (toxins and adhesins). Acellular vaccines are less likely to provoke side effects. They became a part of DTaP vaccines for children. In 2005, two new vaccine products were licensed for use in adolescents and adults that combine the tetanus and diphtheria toxoids with acellular pertussis vaccine. These (Tdap) vaccines
Riggs' disease Riggs himself. Riggs' disease Riggs' disease, also known as pyorrhea of a toothsocket or gingivitis expulsiva, is a historical term for periodontitis (gum disease), The condition was described as a purulent inflammation of the dental periosteum. It was named after American dentist John Mankey Riggs (1811–1885). Riggs' disease was said to produce the progressive necrosis of the alveoli and looseness of the teeth. The teeth may become very loose and fall out of the sockets. Mark Twain wrote briefly about Riggs' disease in his short essay, "Happy Memories of the Dental Chair", in which he claims to have been examined