Bordetella pertussis know which antibody has been detected. The organism is oxidase positive, but urease, nitrate reductase, and citrate negative. It is also not motile. Bordetella pertussis Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus of the genus "Bordetella", and the causative agent of pertussis or whooping cough. Unlike "B. bronchiseptica", "B. pertussis" is not motile. Its virulence factors include pertussis toxin, filamentous hæmagglutinin, pertactin, fimbria, and tracheal cytotoxin. The bacterium is spread by airborne droplets; its incubation period is 9–10 days on average (range 6–20 days). Humans are the only known reservoir for "B. pertussis". The complete "B. pertussis" genome
Peripheral artery disease )Trial. In 2011, pCMV-vegf165 was registered in Russia as the first-in-class gene therapy drug for treatment of PAD, including the advanced stage of critical limb ischemia. Peripheral artery disease Peripheral artery disease (PAD) is an abnormal narrowing of arteries other than those that supply the heart or brain. When narrowing occurs in the heart, it is called coronary artery disease, and in the brain, it is called cerebrovascular disease. Peripheral artery disease most commonly affects the legs, but other arteries may also be involved. The classic symptom is leg pain when walking which resolves with rest, known as intermittent claudication.