Margaret of Anjou Margaret of Anjou Margaret of Anjou (; 23 March 1430 – 25 August 1482) was the Queen of England by marriage to King Henry VI from 1445 to 1461 and again from 1470 to 1471. Born in the Duchy of Lorraine into the House of Valois-Anjou, Margaret was the second eldest daughter of René, King of Naples, and Isabella, Duchess of Lorraine. She was one of the principal figures in the series of dynastic civil wars known as the Wars of the Roses and at times personally led the Lancastrian faction. Owing to her husband's frequent bouts of insanity, Margaret
Facetiae (a quarto with 110 leaves). The second oldest is called Reichling 1919 (100 leaves). The 100-leaf edition, despite having been described elsewhere as the first printing, is now generally held to be later than the 110-leaf edition, which is traditionally thought to be the editio princeps; both were printed in Rome in 1470/1471. An edition from 1473–1476, Hain 13182, was printed somewhere in Poland. Christophorus Valdarfer in Venice likewise printed an edition (with 76 leaves) in 1470/1471, and Andreas Belfortis in Ferrara printed one dated 1471. According to Lotte Hellinga, the Venice edition by Valdarfer is probably older than Lauer's