Margaret of Anjou Margaret of Anjou Margaret of Anjou (; 23 March 1430 – 25 August 1482) was the Queen of England by marriage to King Henry VI from 1445 to 1461 and again from 1470 to 1471. Born in the Duchy of Lorraine into the House of Valois-Anjou, Margaret was the second eldest daughter of René, King of Naples, and Isabella, Duchess of Lorraine. She was one of the principal figures in the series of dynastic civil wars known as the Wars of the Roses and at times personally led the Lancastrian faction. Owing to her husband's frequent bouts of insanity, Margaret
Gervase Clifton (died 1471) May 1471. Clifton married twice, leaving no sons, only two daughters and co-heiresses by his first wife, Isabel Herbert (died c. November 1457), widow of William Scott (died 5 February 1434) of Brabourne, Kent, and daughter of Vincent Herbert ("alias" Finche) of Netherfield, Sussex by his wife Isabel Cralle, daughter and coheiress of Robert Cralle. Their two daughters were: Clifton's second marriage, before 20 March 1463, was to Maud Stanhope (died 30 August 1497), widow firstly of Robert Willoughby, 6th Baron Willoughby de Eresby (died 1452), and secondly of Sir Thomas Neville (died 1460), second son of Richard Neville, 5th