Isca Dumnoniorum but seems to have gone into decline prior to the Roman withdrawal from Britain . The name "Isca Dumnoniorum" is a Latinization of a native Brittonic name describing flowing water, in reference to the River Exe. More exactly, the name seems to have originally meant "full of fish" (cf. Welsh "pysg", "fish"), although it came to be a simple synonym for water (cf. Scottish whiskey). This is also reflected in the modern Welsh name for Exeter: "Caerwysg" meaning "fortified settlement on the river Uisc". The same name was used for the River Usk (modern ) in southern Wales, causing the
Isca Augusta legion was needed to repel a potential invasion from the Continent. The stone from Isca may have been used for building defences on the south coast. There may still have been an occasional military presence as late as the early 4th century, but the fortress was probably later taken over by the people of the surrounding vicus. The basilica of the baths was used as a cattle pen. Recent finds suggest Roman occupation of some kind as late as AD 380. According to the Gildas (followed by Bede), Roman Caerleon was the site of two early Christian martyrdoms in Britain,