Pertussis vaccine wholesale in the developing world at a cost of 15.41 USD per dose as of 2014. Acellular pertussis vaccine (aP) with three or more antigens prevents around 85% of typical whooping cough cases in children. It has higher or similar efficacy to the previously-used whole cell pertussis vaccine, however the efficacy of the acellular vaccine declines faster. Acellular vaccines also cause fewer side effects than whole cell vaccines. Despite widespread vaccination, pertussis has persisted in vaccinated populations and is one of the most common vaccine-preventable diseases. The recent resurgence in pertussis infections is attributed to a combination of waning immunity
Binswanger's disease history of Binswanger's disease and the fact that it was overlooked as a disease for many years means many patients may have been misdiagnosed with Alzheimer's disease. Binswanger's disease Binswanger's disease, also known as subcortical leukoencephalopathy and subcortical arteriosclerotic encephalopathy (SAE), is a form of small vessel vascular dementia caused by damage to the white brain matter. White matter atrophy can be caused by many circumstances including chronic hypertension as well as old age. This disease is characterized by loss of memory and intellectual function and by changes in mood. These changes encompass what are known as executive functions of