Secretion both DNA and proteins. It was discovered in "Agrobacterium tumefaciens", which uses this system to introduce the T-DNA portion of the Ti plasmid into the plant host, which in turn causes the affected area to develop into a crown gall (tumor). "Helicobacter pylori" uses a type IV secretion system to deliver CagA into gastric epithelial cells, which is associated with gastric carcinogenesis. "Bordetella pertussis", the causative agent of whooping cough, secretes the pertussis toxin partly through the type IV system. "Legionella pneumophila", the causing agent of legionellosis (Legionnaires' disease) utilizes a type IVB secretion system, known as the icm/dot (intracellular
Coats' disease been documented in which the condition even reverses itself. However, once total retinal detachment occurs, sight loss is permanent in most cases. Removal of the eye (enucleation) is an option if pain or further complications arise. Coats' disease is named after George Coats. Coats' disease Coats' disease, (also known as exudative retinitis or retinal telangiectasis, sometimes spelled Coates' disease), is a rare congenital, nonhereditary eye disorder, causing full or partial blindness, characterized by abnormal development of blood vessels behind the retina. Coats' disease can also fall under glaucoma. It can have a similar presentation to that of retinoblastoma. The most