Cocooning (immunization) infant beyond what is provided by maternal vaccination. ACIP is recommending that all relatives and caregivers get vaccinated against pertussis at least two weeks before coming into contact with infants. Cocooning (immunization) Cocooning, also known as the Cocoon Strategy, is a vaccination strategy that has been recommended by the Centers for Disease Control and Prevention (CDC) in the United States since 2006. It aims to protect newborn infants from becoming infected with pertussis by administering DTaP/Tdap (tetanus, diphtheria and acellular pertussis) booster vaccine to mothers, family members and any individuals who would come into regular contact with the newborn infant.
Gaucher's disease Gaucher's disease Gaucher's disease or Gaucher disease () (GD) is a genetic disorder in which glucocerebroside (a sphingolipid, also known as glucosylceramide) accumulates in cells and certain organs. The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the enzyme glucocerebrosidase (also known as glucosylceramidase), which acts on glucocerebroside. When the enzyme is defective, glucocerebroside accumulates, particularly in white blood cells and especially in macrophages (mononuclear leukocytes). Glucocerebroside can collect in the spleen, liver, kidneys, lungs, brain, and bone marrow. Manifestations may include