Bordetella pertussis Bordetella pertussis Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus of the genus "Bordetella", and the causative agent of pertussis or whooping cough. Unlike "B. bronchiseptica", "B. pertussis" is not motile. Its virulence factors include pertussis toxin, filamentous hæmagglutinin, pertactin, fimbria, and tracheal cytotoxin. The bacterium is spread by airborne droplets; its incubation period is 9–10 days on average (range 6–20 days). Humans are the only known reservoir for "B. pertussis". The complete "B. pertussis" genome of 4,086,186 base pairs was published in 2003. Pertussis is an infection of the respiratory system characterized by a “whooping” sound when the
Paget–Schroetter disease axillary and subclavian veins. Paget–Schroetter disease Paget–Schroetter disease, also known as Paget–von Schrötter disease, is a form of upper extremity deep vein thrombosis (DVT), a medical condition in which blood clots form in the deep veins of the arms. These DVTs typically occur in the axillary or subclavian veins. The condition is relatively rare. It usually presents in young and otherwise healthy patients, and also occurs more often in males than females. The syndrome also became known as "effort-induced thrombosis" in the 1960s, as it has been reported to occur after vigorous activity, though it can also occur due to