DPT vaccine the Netherlands, pertussis is known as "kinkhoest" and DKTP refers to a combination vaccine against diphtheria, kinkhoest, tetanus, and polio. The usual course of childhood immunization in the USA is five doses between 2 months and 15 years. For adults, Td boosters are recommended every 10 years. In the latter 20th century, vaccinations helped to reduce the incidence of childhood pertussis in the United States. Despite this, reported instances of the disease increased twenty-fold in the early 21st century, resulting in numerous fatalities. Over this time, many parents declined to vaccinate their children against pertussis for fear of side effects.
Alexander disease older patients, bulbar or pseudobulbar symptoms and spasticity predominate. Symptoms of the adult form may also resemble multiple sclerosis. No more than 500 cases have been reported. Alexander disease Alexander disease is one of a group of neurological conditions known as the leukodystrophies, which are ailments caused by anomalies in the myelin, which protects nerve fibers in the brain. According to the National Institute of Neurological Disorders and Stroke, the destruction of white matter is accompanied by the formation of Rosenthal fibers—abnormal clumps of protein that accumulate in astrocytes in the brain. The most common type of Alexander disease is