Pertussis vaccine Japan. A dramatic increase in the incidence of pertussis followed. In the United States, low profit margins and an increase in vaccine-related lawsuits led many manufacturers to stop producing the DPT vaccine by the early 1980s. In 1982, the television documentary "DPT: Vaccine Roulette" by reporter Lea Thompson depicted the lives of children whose severe disabilities were incorrectly blamed on the DPT vaccine. The ensuing negative publicity led to many lawsuits against vaccine manufacturers. By 1985, vaccine manufacturers had difficulty obtaining liability insurance. The price of DPT vaccine skyrocketed, leading providers to curtail purchases, limiting availability. Only one manufacturer remained
Fatty liver disease Fatty liver disease Fatty liver disease (FLD), also known as hepatic steatosis, is a condition where excess fat builds up in the liver. There are two types non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease. NAFLD is made up of simple fatty liver and non-alcoholic steatohepatitis (NASH). Risk factors for NAFLD include diabetes, obesity, and older age. The condition is also associated with other diseases that influence fat metabolism. It is difficult to distinguish alcoholic FLD, which is part of alcoholic liver disease, from nonalcoholic FLD (NAFLD), and both show microvesicular and macrovesicular fatty changes at different stages. Fatty