Pertussis toxin "Bordetella" is that "B. pertussis" produces PT and the other species do not. "Bordetella parapertussis" shows the most similarity to "B. pertussis" and was therefore used for research determining the role of PT in causing the typical symptoms of whooping cough. Rat studies showed the development of paroxysmal coughing, a characteristic for whooping cough, occurred in rats infected with "B. pertussis". Rats infected with "B. parapertussis" or a PT-deficient mutant of "B. pertussis" did not show this symptom; neither of these two strains produced PT. A large group of bacterial exotoxins are referred to as "A/B toxins", in essence because
Kyasanur Forest disease Kyasanur Forest disease Kyasanur Forest disease (KFD) is a tick-borne viral hemorrhagic fever endemic to South Asia. The disease is caused by a virus belonging to the family "Flaviviridae", which also includes yellow fever and dengue fever. The disease was first reported from Kyasanur Forest of Karnataka in India in March 1957. The disease first manifested as an epizootic outbreak among monkeys killing several of them in the year 1957. Hence the disease is also locally known as monkey disease or monkey fever. The similarity with Russian spring-summer encephalitis was noted and the possibility of migratory birds carrying the disease