Issue of Edward III of England – 3 February 1399), 1st Duke of Lancaster, fourth son. From the marriage of John of Gaunt and Blanche of Lancaster, daughter and heiress of the Duke of Lancaster, descended legitimate male heirs, the Lancasters (King Henry IV (1399-1413), who as Henry of Bolingbroke in 1399 deposed his first cousin King Richard II (1377-1399), and was followed by his son King Henry V(1413-1422) and the latter's son King Henry VI (1422-1471). This line ended in 1471 when King Henry VI's son Edward of Westminster, Prince of Wales was killed at the Battle of Tewkesbury and when he himself was deposed
Henry Stafford (c. 1425 – 1471) Henry Stafford (c. 1425 – 1471) Sir Henry Stafford (c. 1425 – 4 October 1471) was the second son of Humphrey Stafford, 1st Duke of Buckingham and Anne Neville, daughter of Ralph de Neville, 1st Earl of Westmorland, and Lady Joan Beaufort. Henry's elder brother, also named Humphrey, died before their father, and so it was Henry's nephew, also Henry, who became the 2nd Duke of Buckingham. Stafford was the third husband of Margaret Beaufort, Countess of Richmond and Derby. The marriage was relatively long and successful and coincided roughly with the minority of Margaret's son, the future Henry VII