Cocooning (immunization) infant beyond what is provided by maternal vaccination. ACIP is recommending that all relatives and caregivers get vaccinated against pertussis at least two weeks before coming into contact with infants. Cocooning (immunization) Cocooning, also known as the Cocoon Strategy, is a vaccination strategy that has been recommended by the Centers for Disease Control and Prevention (CDC) in the United States since 2006. It aims to protect newborn infants from becoming infected with pertussis by administering DTaP/Tdap (tetanus, diphtheria and acellular pertussis) booster vaccine to mothers, family members and any individuals who would come into regular contact with the newborn infant.
Machado–Joseph disease Machado–Joseph disease Machado–Joseph disease (MJD), also known as Machado–Joseph Azorean disease, Machado's disease, Joseph's disease or spinocerebellar ataxia type 3 (SCA3), is a rare autosomal dominantly inherited neurodegenerative disease that causes progressive cerebellar ataxia, which results in a lack of muscle control and coordination of the upper and lower extremities. The symptoms are caused by a genetic mutation that results in an expansion of abnormal "CAG" trinucleotide repeats in the ATXN3 gene that results in an abnormal form of the protein ataxin which causes degeneration of cells in the hindbrain. Some symptoms, such as clumsiness and rigidity, make MJD commonly