Period 6 element heavy metal, lead is a neurotoxin that accumulates both in soft tissues and the bones. Lead poisoning has been documented from ancient Rome, ancient Greece, and ancient China. Bismuth is a chemical element with symbol Bi and atomic number 83. Bismuth, a trivalent other metal, chemically resembles arsenic and antimony. Elemental bismuth may occur naturally uncombined, although its sulfide and oxide form important commercial ores. The free element is 86% as dense as lead. It is a brittle metal with a silvery white color when newly made, but often seen in air with a pink tinge owing to the surface
SB-269970 SB-269970 SB-269970 is a drug and research chemical developed by GlaxoSmithKline used in scientific studies. It is believed to act as a selective 5-HT receptor antagonist (EC = 1.25 nM) (or possibly inverse agonist). A subsequent study in guinea pig at 10 uM showed that it also blocks the α-adrenergic receptor activity. The significant difference in test concentrations, however, confirms the selectivity of SB-269970 for the 5-HT receptor. SB-269970 is used to study the 5-HT receptors which are thought to be involved in the function of several areas of the brain such as the hippocampus and thalamus, and regulation of