Margaret of Anjou Margaret of Anjou Margaret of Anjou (; 23 March 1430 – 25 August 1482) was the Queen of England by marriage to King Henry VI from 1445 to 1461 and again from 1470 to 1471. Born in the Duchy of Lorraine into the House of Valois-Anjou, Margaret was the second eldest daughter of René, King of Naples, and Isabella, Duchess of Lorraine. She was one of the principal figures in the series of dynastic civil wars known as the Wars of the Roses and at times personally led the Lancastrian faction. Owing to her husband's frequent bouts of insanity, Margaret
Henry Stafford (c. 1425 – 1471) Henry Stafford (c. 1425 – 1471) Sir Henry Stafford (c. 1425 – 4 October 1471) was the second son of Humphrey Stafford, 1st Duke of Buckingham and Anne Neville, daughter of Ralph de Neville, 1st Earl of Westmorland, and Lady Joan Beaufort. Henry's elder brother, also named Humphrey, died before their father, and so it was Henry's nephew, also Henry, who became the 2nd Duke of Buckingham. Stafford was the third husband of Margaret Beaufort, Countess of Richmond and Derby. The marriage was relatively long and successful and coincided roughly with the minority of Margaret's son, the future Henry VII