Margaret of Anjou Margaret of Anjou Margaret of Anjou (; 23 March 1430 – 25 August 1482) was the Queen of England by marriage to King Henry VI from 1445 to 1461 and again from 1470 to 1471. Born in the Duchy of Lorraine into the House of Valois-Anjou, Margaret was the second eldest daughter of René, King of Naples, and Isabella, Duchess of Lorraine. She was one of the principal figures in the series of dynastic civil wars known as the Wars of the Roses and at times personally led the Lancastrian faction. Owing to her husband's frequent bouts of insanity, Margaret
Wars of the Roses again won complete victories at Barnet (14 April 1471), where Warwick was killed, and Tewkesbury (4 May 1471) where the Lancastrian heir, Edward of Westminster, Prince of Wales was killed, or perhaps executed after the battle. Queen Margaret was escorted to London as a prisoner and Henry was murdered in the Tower of London several days later, ending the direct Lancastrian line of succession. A period of comparative peace followed, ending with the unexpected death of King Edward in 1483. His surviving brother, Richard, Duke of Gloucester, first moved to prevent the unpopular Woodville family of Edward's widow from participating