Bordetella pertussis produces tracheal cytotoxin, which stops the cilia from beating. This prevents the cilia from clearing debris from the lungs, so the body responds by sending the host into a coughing fit. These coughs expel some bacteria into the air, which are free to infect other hosts. "B. pertussis" has the ability to inhibit the function of the host's immune system. The toxin, known as pertussis toxin (or PTx), inhibits G protein coupling that regulates an adenylate cyclase-mediated conversion of ATP to cyclic AMP. The end result is phagocytes convert too much ATP to cyclic AMP, which can cause disturbances in
Byne's disease high humidity can also affect pyrite (or its more reactive polymorph marcasite) (iron sulphide) fossils in a somewhat similar condition, which is known as pyrite disease. The iron sulfide can react with water and oxygen to form iron sulfates and sulfuric acid, which then can produce Bynesian decay. Byne's disease Byne's disease, more accurately known as Bynesian decay, is a peculiar and permanently damaging condition (resulting from an ongoing chemical reaction) which often attacks mollusk shells that are in storage or on display for long periods of time. Bynesian decay is a form of efflorescence of salts formed by the