Mexican beaded lizard debate among scientists. However, this venom has been found to contain several enzymes useful for manufacturing drugs in the treatment of diabetes, and research on the pharmacological use of its venom is ongoing. Threatened throughout its range by overcollection and habitat loss, it is a CITES protected species. The Guatemalan beaded lizard ("H. charlesbogerti" ) is one of the rarest lizards in the world, with a wild population of fewer than 200. The beaded lizards have one close living relative, the Gila monster ("H. suspectum"), as well as many extinct relatives in the Helodermatidae, whose genetic history may be traced
Mexican beaded lizard is used to store fat so it can survive during months of estivation. Unlike many other lizards, this tail does not autotomize and cannot grow back if broken. The beaded lizard has a forked, pink tongue which it uses to smell, with the help of a Jacobson's organ; it sticks its tongue out to gather scents and touches it to the opening of the organ when the tongue is retracted. Beaded lizards are found in the Pacific drainages from southern Sonora to southwestern Guatemala and two Atlantic drainages, from central Chiapas to southeastern Guatemala. Their habitats are primarily in the