Duke of Alba the House of Álvarez de Toledo (extinct in 1755), the House of Silva (extinct in 1802), and the House of FitzJames, which descends from an illegitimate son of King James II of England. Famous dukes include Don Fernando Alvarez de Toledo, 3rd Duke of Alba, governor of the Spanish Netherlands (references to "Alba" (Alva in Dutch), particularly in the context of Dutch history, are usually about him), and Doña María del Pilar de Silva, 13th Duchess of Alba, a muse of the painter Francisco Goya. Various dukes have married into the families of Christopher Columbus and Cosimo de Medici, as
Enlightenment in Spain such as La Condamine and Alexander von Humboldt, to its overseas empire, usually closed to foreigners. There were extended Royal Botanical Expeditions to Chile and Peru (1777–88), New Granada (1783–1816), and New Spain (1787–1803), which produced a huge number of detailed botanical drawings and specimens destined for the Royal Botanical Garden and the Royal Natural History Cabinet in Madrid. The Malaspina Expedition was an important scientific expedition headed by Spanish naval commander Alejandro Malaspina over five years (1789–94), with naturalists and botanical illustrators gathering information for the Spanish crown. The illustrators on the voyage included José de Pozo, trained at