Mexican beaded lizard debate among scientists. However, this venom has been found to contain several enzymes useful for manufacturing drugs in the treatment of diabetes, and research on the pharmacological use of its venom is ongoing. Threatened throughout its range by overcollection and habitat loss, it is a CITES protected species. The Guatemalan beaded lizard ("H. charlesbogerti" ) is one of the rarest lizards in the world, with a wild population of fewer than 200. The beaded lizards have one close living relative, the Gila monster ("H. suspectum"), as well as many extinct relatives in the Helodermatidae, whose genetic history may be traced
Arizona night lizard young of the lizard are born live, usually one or two around August or September. As the lizard tends not to move about and generally avoids humans, not much is known about it. The species grows to maximum size of about 10 cm. The head is covered with large, smooth plates. Body scales are small, while belly scales are rectangular. The dorsal side is covered with many small dark spots tending to form rows. The eyes are large and round with a vertical pupil (similar to a snake's eye). The species is a secretive lizard. It feeds, reproduces, and lives