Pertussis vaccine wholesale in the developing world at a cost of 15.41 USD per dose as of 2014. Acellular pertussis vaccine (aP) with three or more antigens prevents around 85% of typical whooping cough cases in children. It has higher or similar efficacy to the previously-used whole cell pertussis vaccine, however the efficacy of the acellular vaccine declines faster. Acellular vaccines also cause fewer side effects than whole cell vaccines. Despite widespread vaccination, pertussis has persisted in vaccinated populations and is one of the most common vaccine-preventable diseases. The recent resurgence in pertussis infections is attributed to a combination of waning immunity
Blount's disease Blount's disease Blount's disease is a growth disorder of the tibia (shin bone) that causes the lower leg to angle inward, resembling a bowleg. It is also known as "tibia vara". It is named after Walter Putnam Blount (1900–1992), an American pediatric orthopedic surgeon. It has also been known as Mau-Nilsonne Syndrome, after C. Mau and H. Nilsonne, who published early case reports of the condition. Bowing of one or both legs that may: Failure to treat Blount's disease may lead to progressive deformity.Blount's disease may come back after surgery, especially in younger children. Because of the bowing, a leg-length