Pertussis toxin other lung cells produce a variety of chemokines. PT has been found to inhibit the early transcription of keratinocyte-derived chemokine, macrophage inflammatory protein 2 and LPS-induced CXC chemokine. Eventually, PT causes lymphocytosis, one of the systemic manifestations of whooping cough. PT, a decisive virulence determinant of "B. pertussis", is able to cross the blood–brain barrier by increasing its permeability. As a result, PT can cause severe neurological complications; however, recently it has been found that the medicinal usage of "Pertussis" toxin can promote the development of regulatory T cells and prevent central nervous system autoimmune disease, such as multiple sclerosis.
Byne's disease high humidity can also affect pyrite (or its more reactive polymorph marcasite) (iron sulphide) fossils in a somewhat similar condition, which is known as pyrite disease. The iron sulfide can react with water and oxygen to form iron sulfates and sulfuric acid, which then can produce Bynesian decay. Byne's disease Byne's disease, more accurately known as Bynesian decay, is a peculiar and permanently damaging condition (resulting from an ongoing chemical reaction) which often attacks mollusk shells that are in storage or on display for long periods of time. Bynesian decay is a form of efflorescence of salts formed by the