Margaret of Anjou Margaret of Anjou Margaret of Anjou (; 23 March 1430 – 25 August 1482) was the Queen of England by marriage to King Henry VI from 1445 to 1461 and again from 1470 to 1471. Born in the Duchy of Lorraine into the House of Valois-Anjou, Margaret was the second eldest daughter of René, King of Naples, and Isabella, Duchess of Lorraine. She was one of the principal figures in the series of dynastic civil wars known as the Wars of the Roses and at times personally led the Lancastrian faction. Owing to her husband's frequent bouts of insanity, Margaret
William Brandon (standard-bearer) the son of Sir Maurice Bruyn. She was the widow of Thomas Tyrrell of Heron, Essex, whom she had married before 17 February 1461/1462, and who died after 3 July 1471, c. 13 October 1473, of the City of London, of Beckenham, Kent and of South Ockendon, Essex. She was a grand-daughter of Sir Maurice Bruyn (d. 1466), and daughter and co-heiress of Sir Henry Bruyn (d. 1461) by Elizabeth Darcy (died c. 1471), daughter of Sir Robert Darcy of Maldon, Essex. Elizabeth Bruyn's paternal aunt, Joan Bruyn, married John Digges, great-grandfather of the scientist, Leonard Digges. On her father's