The Adventures of Sherlock Holmes (film) Rathbone as Sherlock Holmes and Nigel Bruce as Dr. John Watson, the final film produced by Fox, and the last in the Rathbone/Bruce series to be set in the original Victorian London period. The further twelve films produced by Universal Pictures and starring Rathbone/Bruce would take place in contemporaneous times (i.e. the 1940s). George Zucco stars as Holmes's nemesis Professor Moriarty. The picture follows famous detective Sherlock Holmes and his assistant Doctor Watson as they attempt to foil their archenemy Professor Moriarty who targets a wealthy family and plots the theft of the Crown Jewels. The film was supposedly based
Adaptations of Sherlock Holmes Detective: Sherlock Holmes". The series is written by Christopher Sequeira with covers by Academy Award winning artist Dave Elsey. In 2010, Boom! Studios published a four-part series entitled "Muppet Sherlock Holmes" which featured Gonzo as Holmes, Fozzie Bear as Dr. Watson, and Kermit the Frog as Inspector Lestrade. In 2013, "New Paradigm Studios" began publishing a monthly, ongoing series entitled "Watson and Holmes." The series re-imagines Sherlock Holmes and Dr. Watson as living in the 21st Century and living in Harlem. It has been estimated that Sherlock Holmes is the most prolific screen character in the history of cinema. The