The Adventures of Sherlock Holmes (film) Rathbone as Sherlock Holmes and Nigel Bruce as Dr. John Watson, the final film produced by Fox, and the last in the Rathbone/Bruce series to be set in the original Victorian London period. The further twelve films produced by Universal Pictures and starring Rathbone/Bruce would take place in contemporaneous times (i.e. the 1940s). George Zucco stars as Holmes's nemesis Professor Moriarty. The picture follows famous detective Sherlock Holmes and his assistant Doctor Watson as they attempt to foil their archenemy Professor Moriarty who targets a wealthy family and plots the theft of the Crown Jewels. The film was supposedly based
Adaptations of Sherlock Holmes and boredom", this friend being an opium-addicted and increasingly weak Sherlock Holmes. Rupert Everett plays the Great Detective. 2002 also saw the made for television cable movie, "Case of Evil", about a 20-something Sherlock Holmes (James D'Arcy) and a Doctor Watson who worked as an early practitioner of autopsies, on the trail of Holmes' archenemy, Professor Moriarty (Vincent D'Onofrio). An adaptation of "The Speckled Band" aired on the early TV anthology series "Your Show Time", and starred Alan Napier as Holmes and Melville Cooper as Watson. John Cleese played Holmes in a 1973 episode of "Comedy Playhouse": "Elementary My Dear