Felix Hoffmann to investigate the substance's efficacy and tolerability had been completed, it was found to be an analgesic, antipyretic and antiinflammatory substance. The company then worked to develop a cost-effective production process that would facilitate the promising active ingredient to be supplied as a pharmaceutical product. In 1899 it was marketed for the first time under the trade name "Aspirin", initially as a powder supplied in glass bottles. He also synthesized diamorphine (heroin), previously achieved by Charles Romley Alder Wright. Following the synthesis of aspirin, Hoffmann moved to the pharmaceutical marketing department where he stayed until his retirement in 1928. He
Illegal drug trade in the Philippines properties are becoming more favorable to drug syndicates as sites of illegal drug production. Methamphetamine remains more feasible to sell in the Philippines than cocaine, a more costly illegal drug. Owing to its geographical location, international drug syndicates use the Philippines as a transit hub for the illegal drug trade. Some local drug syndicates are also involved in the international illegal drug trade, and utilize drug mules to transport small amounts of illegal drugs to other countries. Some overseas Filipino workers have been utilized by drug syndicates as drug mules, either knowingly or unknowingly. Most Filipino drug mules, mainly women,