The Adventures of Sherlock Holmes (film) Rathbone as Sherlock Holmes and Nigel Bruce as Dr. John Watson, the final film produced by Fox, and the last in the Rathbone/Bruce series to be set in the original Victorian London period. The further twelve films produced by Universal Pictures and starring Rathbone/Bruce would take place in contemporaneous times (i.e. the 1940s). George Zucco stars as Holmes's nemesis Professor Moriarty. The picture follows famous detective Sherlock Holmes and his assistant Doctor Watson as they attempt to foil their archenemy Professor Moriarty who targets a wealthy family and plots the theft of the Crown Jewels. The film was supposedly based
Adaptations of Sherlock Holmes as Dr Watson, in "The Hound of the Baskervilles" (2000), "The Royal Scandal" (2001), "The Sign of Four" (2001) and "The Case of the Whitechapel Vampire" (2002). 2002 saw a new version of "The Hound of the Baskervilles" featuring Richard Roxburgh. Ian Hart played Dr. Watson then and also in the 2004 BBC airing of "Sherlock Holmes and the Case of the Silk Stocking", alternatively billed as "The Return of Sherlock Holmes". An original screenplay "based on the character created by Sir Arthur Conan Doyle", this film takes place in 1902, with Dr. Watson "saving a dear friend from narcotics