Controlled Drug in the United Kingdom classification of medicines. Special responsibilities are placed upon pharmaceutical wholesalers, pharmacies and doctors in the stocking, distribution, issuing of prescriptions, supply and disposal of items listed under the first three of the schedules. The regulations have been further tightened since Dr Harold Shipman used diamorphine to murder hundreds of his patients during the late 20th century. Drugs which are not used medically, and thus their possession and supply is prohibited; e.g. cannabis and LSD except when licensed by the Home Office to carry out research. Substances subject to the full controlled drug requirements; e.g. diamorphine (heroin), pethidine, cocaine, methadone, methylphenidate,
Illegal drug trade the supply and demand for marijuana during this time period. Corruption in Mexico has contributed to the domination of Mexican cartels in the illicit drug trade. Since the beginning of the 20th century, Mexico's political environment allowed the growth of drug-related activity. The loose regulation over the transportation of illegal drugs and the failure to prosecute known drug traffickers and gangs increased the growth of the drug industry. Toleration of drug trafficking has undermined the authority of the Mexican government and has decreased the power of law enforcement officers in regulation over such activities. These policies of tolerance fostered the