Felix Hoffmann to investigate the substance's efficacy and tolerability had been completed, it was found to be an analgesic, antipyretic and antiinflammatory substance. The company then worked to develop a cost-effective production process that would facilitate the promising active ingredient to be supplied as a pharmaceutical product. In 1899 it was marketed for the first time under the trade name "Aspirin", initially as a powder supplied in glass bottles. He also synthesized diamorphine (heroin), previously achieved by Charles Romley Alder Wright. Following the synthesis of aspirin, Hoffmann moved to the pharmaceutical marketing department where he stayed until his retirement in 1928. He
Illegal drug trade in the Philippines the Philippines as, "not only a transhipment point, but also a key producer of synthetic drugs for all of Asia" in a report made in 2009. In December 2013, the Philippine National Police - Anti-Illegal Drugs Special Operations Task Force and the Philippine Drug Enforcement confirmed reports that the Mexican Sinaloa Cartel had started operations in the country. About nine Chinese drug cartels are involved on most illegal drug trade in the Philippines. The U.S. Department of State found out that Chinese drug cartels are behind the trade of methamphetamine hydrochloride on the Philippines. The president divulged the names of