Controlled Drug in the United Kingdom classification of medicines. Special responsibilities are placed upon pharmaceutical wholesalers, pharmacies and doctors in the stocking, distribution, issuing of prescriptions, supply and disposal of items listed under the first three of the schedules. The regulations have been further tightened since Dr Harold Shipman used diamorphine to murder hundreds of his patients during the late 20th century. Drugs which are not used medically, and thus their possession and supply is prohibited; e.g. cannabis and LSD except when licensed by the Home Office to carry out research. Substances subject to the full controlled drug requirements; e.g. diamorphine (heroin), pethidine, cocaine, methadone, methylphenidate,
Analgesic nephropathy these medications, specifically combinations that include phenacetin. For this reason, it is also called analgesic abuse nephropathy. Murray prefers the less judgmental analgesic-associated nephropathy. Both terms are abbreviated to the acronym AAN, by which the condition is also commonly known. Analgesic nephropathy Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, phenacetin, and paracetamol. The term usually refers to damage induced by excessive use of combinations of these medications, especially combinations that include phenacetin. It may also be used to describe kidney injury from any single analgesic medication. The specific kidney injuries induced by analgesics