Bayer including pneumonia and tuberculosis. Bayer scientists were not the first to make heroin, but the company led the way in commercializing it. "Heroin" was a Bayer trademark until after World War I. In 1903 Bayer licensed the patent for the hypnotic drug diethylbarbituric acid from its inventors Emil Fischer and Joseph von Mering. It was marketed under the trade name Veronal as a sleep aid beginning in 1904. Systematic investigations of the effect of structural changes on potency and duration of action at Bayer led to the discovery of phenobarbital in 1911 and the discovery of its potent anti-epileptic activity
Compound analgesic Compound analgesic Compound analgesics are those with multiple active ingredients; they include many of the stronger prescription analgesics. Active ingredients that have been commonly used in compound analgesics include: Several such formulations have disappeared from over-the-counter status in drug store aisles and other retail outlets. One example is APC (aspirin, phenacetin, and caffeine) compound tablets common from the 1940s to 1983; because of harmful side effects of phenacetin, Anacin in the U.S. was reformulated to eliminate it; while Vincent's APC is no longer sold. Some others have been judged to contribute too often to substance abuse. Another example is Bex,