Oophorectomy appears to be marginally higher for short-term HRT after oophorectomy or marginally lower for short-term HRT after oophorectomy in combination with mastectomy. This result can probably be generalized to other women at high risk in whom short-term (i.e., one- or two-year) treatment with estrogen for hot flashes may be acceptable. Oophorectomy Oophorectomy (from Greek , , 'egg-bearing' + , , 'a cutting out of') is the surgical removal of an ovary or ovaries. The surgery is also called ovariectomy, but this term is mostly used in reference to animals, e.g. the surgical removal of ovaries from laboratory animals. Removal of
Oophorectomy menopause. The reported risks and adverse effects include premature death, cardiovascular disease, cognitive impairment or dementia, parkinsonism, osteoporosis and bone fractures, decline in psychological well-being, and decline in sexual function. Hormone replacement therapy does not always reduce the adverse effects. Oophorectomy is associated with significantly increased all-cause long-term mortality except when performed for cancer prevention in carriers of high-risk BRCA mutations. This effect is particularly pronounced for women who undergo oophorectomy before age 45. The effect is not limited to women who have oophorectomy performed before menopause; an impact on survival is expected even for surgeries performed up to the