Bombyx mori to produce proteins, including pharmacological drugs, in the place of silk proteins. "Bombyx mori" females are also one of the few organisms with homologous chromosomes held together only by the synaptonemal complex (and not crossovers) during meiosis. Kraig Biocraft Laboratories has used research from the Universities of Wyoming and Notre Dame in a collaborative effort to create a silkworm that is genetically altered to produce spider silk. In September 2010, the effort was announced as successful. Researchers at Tufts developed scaffolds made of spongy silk that feel and look similar to human tissue. They are implanted during reconstructive surgery to
Bombyx mandarina true or mulberry silkmoths. The origin of the domesticated silkmoth is enigmatic. It has been suggested that it is the survivor of an extinct species which diverged from the ancestors of "Bombyx mandarina" millions of years ago. However, this is based on an untenable molecular clock hypothesis that assumes that wild and domestic silkmoths evolved equally fast after their lineages diverged. Rather, the effects of artificial selection have accelerated evolution in the domestic form to a point where it is hard to trace the origin of the numerous breeds of domestic silkworms even with the most modern molecular phylogeny methods.