Sherlock Holmes early 1900s, H. A. Saintsbury took over the role from Gillette for a tour of the play. Between this play and Conan Doyle's own stage adaptation of "The Adventure of the Speckled Band", Saintsbury portrayed Holmes over 1,000 times. Basil Rathbone played Holmes and Nigel Bruce played Watson in fourteen U.S. films (two for 20th Century Fox and a dozen for Universal Pictures) from 1939 to 1946, and in "The New Adventures of Sherlock Holmes" on the Mutual radio network from 1939 to 1946 (before the role of Holmes passed to Tom Conway). While the Fox films were period pieces,
Adaptations of Sherlock Holmes Asylum produced "Sherlock Holmes", which is intended to capitalize on Guy Ritchie's film. It stars new actor Ben Syder as Holmes and "Torchwood" actor Gareth David Lloyd as Watson. It was shot in Wales and directed by Rachel Lee Goldenberg. In the 2015 film "Mr. Holmes", Ian McKellen portrays the detective as a 93-year-old retiree, living in a countryside farmhouse with his housekeeper (Laura Linney) and her son. As his memory deteriorates, he struggles to recall the last case of his career, which sent him into retirement. In the animated 2018 film "Sherlock Gnomes", Johnny Depp portrayed a gnome counterpart