Bombyx mori the molecular identification of the first known pheromone, bombykol, which required extracts from 500,000 individuals, due to the very small quantities of pheromone produced by any individual worm. Currently, research is focusing on genetics of silkworms and the possibility of genetic engineering. Many hundreds of strains are maintained, and over 400 Mendelian mutations have been described. Another source suggests 1,000 inbred domesticated strains are kept worldwide. One useful development for the silk industry is silkworms that can feed on food other than mulberry leaves, including an artificial diet. Research on the genome also raises the possibility of genetically engineering silkworms
Flacherie Flacherie Flacherie (literally: "flaccidness") is a disease of silkworms, caused by silkworms eating infected or contaminated mulberry leaves. Flacherie infected silkworms look weak and can die from this disease. Silkworm larvae that are about to die from Flacherie are a dark brown. There are two kinds of flacherie: essentially, infectious (viral) flacherie and noninfectious ("bouffee") flacherie. Both are technically a lethal diarrhea. Bouffée flacherie is caused by heat waves ("bouffée" means "sudden heat spell" in French). Viral flacherie is ultimately caused by infection with "Bombyx mori" infectious flacherie virus (BmIFV, Iflaviridae), "Bombyx mori" densovirus (BmDNV, Parvoviridae) or "Bombyx mori" cypovirus