Felix Hoffmann to investigate the substance's efficacy and tolerability had been completed, it was found to be an analgesic, antipyretic and antiinflammatory substance. The company then worked to develop a cost-effective production process that would facilitate the promising active ingredient to be supplied as a pharmaceutical product. In 1899 it was marketed for the first time under the trade name "Aspirin", initially as a powder supplied in glass bottles. He also synthesized diamorphine (heroin), previously achieved by Charles Romley Alder Wright. Following the synthesis of aspirin, Hoffmann moved to the pharmaceutical marketing department where he stayed until his retirement in 1928. He
Illegal drug trade in the Philippines 150 government officials that have been found to be involved in illegal drug trade. There have also been allegations of government officials' involvement in illegal drug trade at the New Bilibid Prison. A week after Rodrigo Duterte was inaugurated on June 30, 2016, it was reported that about 1,000 drug pushers and users had been killed in police operations and around 1,000 killed in drug-related incidents. A March 2017 INCSR report by the United States State Department estimated that 6000 extrajudicial killings had resulted from "police actions and vigilantism". Ifugao congressman Teodoro Baguilat and senator Leila de Lima called for