Silk remarkable mechanical properties, comparative biocompatibility, tunable degradation rates "in vitro" and "in vivo", the ease to load cellular growth factors (for example, BMP-2), and the ability to be processed into several other formats such as films, gels, particles, and scaffolds. Silks from "Bombyx mori", a kind of cultivated silkworm, are the most widely investigated silks. Silks derived from "Bombyx mori" are generally made of two parts: the silk fibroin fiber which contains a light chain of 25kDa and a heavy chain of 350kDa (or 390kDa) linked by a single disulfide bond and a glue-like protein, sericin, comprising 25 to 30
Dauer larva as "L1", "L2", "L3" and "L4". After L4, animals moult to the reproductive adult stage. However, when the environment is unfavorable, L1 and L2 animals have the option to divert their development from reproduction to dauer formation. Signals such as temperature, food supply, and levels of a dauer-inducing pheromone, a population density cue, influence this dauer decision. Dauer larvae are thus considered an alternative L3 stage larva, and this stage is sometimes preceded by L2d. L2d animals are considered pre-dauer and are characterised by delayed development and dark intestines produced by storage of fat. L2d larvae can either continue normal