The Adventures of Sherlock Holmes (film) Rathbone as Sherlock Holmes and Nigel Bruce as Dr. John Watson, the final film produced by Fox, and the last in the Rathbone/Bruce series to be set in the original Victorian London period. The further twelve films produced by Universal Pictures and starring Rathbone/Bruce would take place in contemporaneous times (i.e. the 1940s). George Zucco stars as Holmes's nemesis Professor Moriarty. The picture follows famous detective Sherlock Holmes and his assistant Doctor Watson as they attempt to foil their archenemy Professor Moriarty who targets a wealthy family and plots the theft of the Crown Jewels. The film was supposedly based
Basil Rathbone produced by Fox in 1939), were set in the late Victorian times of the original stories. The later installments, produced by Universal, beginning with "Sherlock Holmes and the Voice of Terror" (1942), were set in contemporary times. The first three had World War II-related plots. Concurrent with the films, Rathbone and Bruce reprised their film roles in a radio series, "The New Adventures of Sherlock Holmes", which began in October 1939. Rathbone appeared in the radio series as long as the film series was active, but after the films lapsed in 1946, Rathbone ceded his radio part to Tom Conway.