Charles Romley Alder Wright several hours and produced a more potent, acetylated form of morphine, now called "diamorphine (or diacetylmorphine)", also known as heroin. After Wright's death, Heinrich Dreser, a chemist at Bayer Laboratories, continued to test heroin. Bayer marketed it as an analgesic and 'sedative for coughs' in 1898. When its addictive potential was recognized, Bayer ceased its production in 1913. In 1892, Wright was the first to report the existence of the stoichiometric intermetallic compound AlSb (aluminium antimonide), which is now recognized as a compound semiconductor with potential use in high-frequency, low-power consumption microelectronics applications, as well as gamma radiation detection. In
Analgesic nephropathy kidney toxicities of NSAIDs and the antipyretics phenacetin and paracetamol may combine to give rise to analgesic nephropathy. A committee of investigators reported in 2000 that there was insufficient evidence to suggest that non-phenacetin analgesics by themselves are associated with analgesic nephropathy. Proper kidney function depends upon adequate blood flow to the kidney. Kidney blood flow is a complex, tightly regulated process that relies on a number of hormones and other small molecules, such as prostaglandins. Under normal circumstances, prostaglandin E2 (PGE) produced by the kidney is necessary to support adequate blood flow to the kidney. Like all prostaglandins, PGE