George Hogarth Pringle includes descriptions of Pringle's work. He was also visiting surgeon to the Benevolent Asylum and surgeon to the King's School and Newington College, a Wesleyan School sited at that time at Silverwater. George Hogarth Pringle wrote a letter to the "Sydney Morning Herald" published on 30 January 1868. This was on ‘the treatment of compound fractures with carbolic acid by my old friend and hospital colleague Joseph Lister”, and was essentially a case report describing Pringle’s successful use of antiseptic principles for a compound fracture. He went on "Having at present under my care, what I may call a representative
Shikimic acid is also an alternative to shikimic acid as a starting material for the synthesis of oseltamivir. Shikimate can be used to synthesise (6S)-6-Fluoroshikimic acid, an antibiotic which inhibits the aromatic biosynthetic pathway. Glyphosate, the active ingredient in the herbicide Roundup, kills plants by interfering with the shikimate pathway in plants. More specifically, glyphosate inhibits the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). "Roundup Ready" genetically modified crops overcome that inhibition. Shikimic acid Shikimic acid, more commonly known as its anionic form shikimate, is a cyclohexene, a cyclitol and a cyclohexanecarboxylic acid. It is an important biochemical metabolite in plants and microorganisms. Its name