Cholecystitis or scarring of the bile duct. The greatest risk factor for cholecystitis is gallstones. Risk factors for gallstones include female sex, increasing age, pregnancy, oral contraceptives, obesity, diabetes mellitus, ethnicity (Native North American), rapid weight loss. Gallstones blocking the flow of bile account for 90% of cases of cholecystitis (acute calculous cholecystitis). Blockage of bile flow leads to thickening and buildup of bile causing an enlarged, red, and tense gallbladder. The gallbladder is initially sterile but often becomes infected by bacteria, predominantly "E. coli", "Klebsiella", "Streptococcus", and "Clostridium" species. Inflammation can spread to the outer covering of the gallbladder and
Children Affected by AIDS Foundation vision and leadership, the Foundation has raised more than $33 million since its inception. In 2007, Joe’s health again began to falter due to the long-term effects of HIV coupled with medication side effects, and it became necessary for him to go on an extended medical leave from Mattel. Joe now focuses all of his time and energy on taking care of his health and continuing to help children affected by HIV/AIDS. Mattel, Inc. continues to provide major funding and support to the Foundation. Joe Cristina currently serves as the Board Chair for CAAF. CAAF has a staff of 7