Amount of substance Amount of substance Amount of substance is a standard-defined quantity that measures the size of an ensemble of particles, such as atoms, molecules, electrons, and other particles. It is sometimes referred to as chemical amount. The International System of Units (SI) defines the amount of substance to be proportional to the number of entities present. The SI unit for amount of substance is the mole. It has the unit symbol mol. The proportionality constant is the inverse of the Avogadro constant. The mole is defined as the amount of substance that contains an equal number of elementary entities as there
Ground substance as hyaluronic acid, heparan sulfate, dermatan sulfate, and chondroitin sulfate, proteoglycans which GAGs are bound to, and glycoproteins. Components of the ground substance are secreted by fibroblasts. Usually it is not visible on slides, because it is lost during staining in the preparation process. Link proteins such as vinculin, spectrin and actomyosin stabilize the proteoglycans and organize elastic fibers in the ECM. Changes in the density of ground substance can allow collagen fibers to form aberrant cross-links. Loose connective tissue is characterized by few fibers and cells, and a relatively large amount of ground substance. Dense connective tissue has a