Radium bromide Institute had four grams of radium total, which at the time was more than half the world supply. Countries all over the world set out to make as much radium as possible, a time consuming and expensive task. It was reported in "Science" magazine in 1919 that the United States had produced approximately 55 grams of radium since 1913, which was also more than half the radium produced in the world at the time. A principal source for radium is pitchblende, which holds a total of 257 mg of radium per ton of UO. Obviously with so little product recovered
Radium-223 kBq/ml), sodium chloride, and other ingredients for intravenous injection. Algeta ASA was later acquired by Bayer who is now the sole owner of Xofigo. The recommended regimen is six treatments of 55 kBq/kg (1.3 uCi per kg), repeated at 4-week intervals. The use of radium-223 to treat metastatic bone cancer relies on the ability of alpha radiation from radium-223 and its short-lived decay products to kill cancer cells. Radium is preferentially absorbed by bone by virtue of its chemical similarity to calcium, with most radium-223 that is not taken up by the bone being cleared, primarily via the gut, and