Cholecystitis or scarring of the bile duct. The greatest risk factor for cholecystitis is gallstones. Risk factors for gallstones include female sex, increasing age, pregnancy, oral contraceptives, obesity, diabetes mellitus, ethnicity (Native North American), rapid weight loss. Gallstones blocking the flow of bile account for 90% of cases of cholecystitis (acute calculous cholecystitis). Blockage of bile flow leads to thickening and buildup of bile causing an enlarged, red, and tense gallbladder. The gallbladder is initially sterile but often becomes infected by bacteria, predominantly "E. coli", "Klebsiella", "Streptococcus", and "Clostridium" species. Inflammation can spread to the outer covering of the gallbladder and
What Is History? to suit their facts, and takes part in a dialogue between past and present. Summing up his argument, Carr puts forward his own answer to the question of "what is history?", remarking that "it is a continuous process of interaction between the historian and his facts, an unending dialogue between the past and the present." it is precisely for matters of this kind that the historian is entitled to rely on what have been called the auxiliary sciences of history In his second chapter, Carr focuses on the influence that society plays on forming the approach of the historian and