Cholecystitis or scarring of the bile duct. The greatest risk factor for cholecystitis is gallstones. Risk factors for gallstones include female sex, increasing age, pregnancy, oral contraceptives, obesity, diabetes mellitus, ethnicity (Native North American), rapid weight loss. Gallstones blocking the flow of bile account for 90% of cases of cholecystitis (acute calculous cholecystitis). Blockage of bile flow leads to thickening and buildup of bile causing an enlarged, red, and tense gallbladder. The gallbladder is initially sterile but often becomes infected by bacteria, predominantly "E. coli", "Klebsiella", "Streptococcus", and "Clostridium" species. Inflammation can spread to the outer covering of the gallbladder and
The Description of the Human Body soul. A sick or injured body does not do what we want or moves in ways we do not want. He believed the death of the body stopped it from being fit to bring about movement. This did not necessarily happen because the soul left the body. René Descartes believed the body could exist through mechanical means alone. This included digestion, blood circulation, muscle movement and some brain function. He felt we all know what the human body is like because animals have similar bodies and we have all seen them opened up. He saw the body as a machine.