Glenn Frey married twice. From 1983 to 1988, he was married to artist Janie Beggs. He married dancer and choreographer Cindy Millican in 1990. They had three children: a daughter Taylor, and two sons Deacon and Otis, and remained together until his death. Deacon Frey, since his father's death, has toured with the surviving Eagles. From about 2000, Frey had suffered from rheumatoid arthritis, which affected various joints of his body. The medication that he was prescribed to control the disease eventually led to colitis and pneumonia, and in November 2015, the Eagles announced that they were postponing their appearance at the
Glenn Frey Kennedy Center Honors as Frey required surgery for intestinal problems and a lengthy recovery period. Following surgery, he was placed in a medically-induced coma at Columbia University Medical Center. Frey died there on January 18, 2016 at the age of 67 from complications of rheumatoid arthritis, acute ulcerative colitis, and pneumonia, while recovering from gastrointestinal tract surgery. Medications for rheumatoid arthritis or ulcerative colitis can compromise the immune system's ability to fight off pneumonia. In January 2018, Frey's wife filed a suit against Mount Sinai Hospital and gastroenterologist Steven Itzkowitz for the wrongful death of Frey. Frey was publicly mourned