Rizzoli & Isles Rizzoli & Isles Rizzoli & Isles is a TNT television series starring Angie Harmon as police detective Jane Rizzoli and Sasha Alexander as medical examiner Dr. Maura Isles. The one-hour drama is based on the series of "Rizzoli & Isles" novels by Tess Gerritsen. It premiered on July 12, 2010, and aired 105 episodes in seven seasons, concluding on September 5, 2016. The series' backstory is inspired by the Maura Isles/Jane Rizzoli series of novels by Tess Gerritsen. Rizzoli appears in the series' first novel, "The Surgeon", and Isles is introduced in the second, "The Apprentice", which serves as the
Rizzoli & Isles who was unaware of his expulsion—Hoyt, aided by a third apprentice, manages to capture Jane and Maura, only to have Jane beat Hoyt and then stab him when he and his apprentice try to kill Maura. The untitled project was on TNT's development slate as early as March 2008. In October 2009, TNT placed a cast-contingent pilot order under the original title, "Rizzoli". The pilot script was written by Janet Tamaro. Angie Harmon was the first actress cast, taking the title role of police detective Jane Rizzoli. Sasha Alexander won the role of medical examiner Dr. Maura Isles after auditioning