Radium bromide Institute had four grams of radium total, which at the time was more than half the world supply. Countries all over the world set out to make as much radium as possible, a time consuming and expensive task. It was reported in "Science" magazine in 1919 that the United States had produced approximately 55 grams of radium since 1913, which was also more than half the radium produced in the world at the time. A principal source for radium is pitchblende, which holds a total of 257 mg of radium per ton of UO. Obviously with so little product recovered
Radium in the early 1900s are not used anymore because of the harmful effects radium bromide exposure caused. Some examples of these effects are anaemia, cancer, and genetic mutations. Safer gamma emitters such as Co, which is less costly and available in larger quantities, are usually used today to replace the historical use of radium in this application. Early in the 1900s, biologists used radium to induce mutations and study genetics. As early as 1904, Daniel MacDougal used radium in an attempt to determine whether it could provoke sudden large mutations and cause major evolutionary shifts. Thomas Hunt Morgan used radium