Mammary gland gestation, serum progesterone remains at a stably high concentration so signaling through its receptor is continuously activated. As one of the transcribed genes, Wnts secreted from mammary epithelial cells act paracrinely to induce more neighboring cells' branching. When the lactiferous duct tree is almost ready, "leaves" alveoli are differentiated from luminal epithelial cells and added at the end of each branch. In late pregnancy and for the first few days after giving birth, colostrum is secreted. Milk secretion (lactation) begins a few days later due to reduction in circulating progesterone and the presence of another important hormone prolactin, which mediates
John Augustus Just known as the Just Milk Process) involves first treating a sample of milk with calcium chloride to reduce its acidity and then with alkaline hypochlorite to preserve the fatty acids in the finished product. The treated milk is then rolled between two large, horizontal steam-heated rollers. This action dries the milk; it is then scraped off and collected. Just was instrumental in founding Just's Food Company and the Just Milk Process, which was incorporated on November 15, 1902 with $10,000 in capital. The main product of the company was an infant food, which contained his famous evaporated milk and was