Cholecystitis or scarring of the bile duct. The greatest risk factor for cholecystitis is gallstones. Risk factors for gallstones include female sex, increasing age, pregnancy, oral contraceptives, obesity, diabetes mellitus, ethnicity (Native North American), rapid weight loss. Gallstones blocking the flow of bile account for 90% of cases of cholecystitis (acute calculous cholecystitis). Blockage of bile flow leads to thickening and buildup of bile causing an enlarged, red, and tense gallbladder. The gallbladder is initially sterile but often becomes infected by bacteria, predominantly "E. coli", "Klebsiella", "Streptococcus", and "Clostridium" species. Inflammation can spread to the outer covering of the gallbladder and
Body part as an object group with average 7.2 years of formal education) make significantly more BPO errors than the average adult population. It has been found that BPO errors (i.e. use of BPO pantomimes in place of the IO pantomimes dominant in typical adult individuals) are made by patients with schizophrenia. Given that BPO errors are associated with apraxia, and that past research has indicated that schizophrenic patients have apraxia-like symptoms, this is perhaps not a surprising finding. This BPO-schizophrenia association has not been extensively explored to date, and more research is required in order to better understand it. Body part as an object