Cholecystitis as choledocholithiasis. People who are old, have diabetes, chronic illness, or who are immunocompromised may have vague symptoms that may not include fever or localized tenderness. A number of complications may occur from cholecystitis if not detected early or properly treated. Signs of complications include high fever, shock and jaundice. Complications include the following: Cholecystitis causes the gallbladder to become distended and firm. Distension can lead to decreased blood flow to the gallbladder, causing tissue death and eventually gangrene. Once tissue has died, the gallbladder is at greatly increased risk of rupture (perforation). Rupture can also occur in cases of
The World Is What It Is in 1996. The biography has been extensively reviewed: the reviewers include Paul Theroux, who wrote an earlier book about Naipaul. The biography was selected by the editors of the "New York Times Book Review" as one of the "Times"' "10 Best Books of 2008". It won the 2008 National Book Critics Circle Award in Biography, and the British literary award the Hawthornden Prize. The World Is What It Is The World Is What It Is: The Authorized Biography of V. S. Naipaul is a biography of the Nobel Prize-winning author V. S. Naipaul by Patrick French. It was published in