Group 12 element people in the 17th century. German chemist Andreas Marggraf is usually given credit for discovering pure metallic zinc in a 1746 experiment by heating a mixture of calamine and charcoal in a closed vessel without copper to obtain a metal. Experiments on frogs by the Italian doctor Luigi Galvani in 1780 with brass paved the way for the discovery of electrical batteries, galvanization and cathodic protection. In 1880, Galvani's friend, Alessandro Volta, invented the Voltaic pile. The biological importance of zinc was not discovered until 1940 when carbonic anhydrase, an enzyme that scrubs carbon dioxide from blood, was shown to
Bioabsorbable metallic glass numerous ternary alloys along the 350 °C isotherm of the Mg-Zn-Ca system. Ternary Ca-Mg-Zn bulk metallic glasses were also discovered in 2005. Similar to the Mg-Zn-Ca, these two amorphous alloys are both bioresorbable metallic glasses and are based on the same "Mg-Zn-Ca ternary system". The elements are displayed in order of decreasing atomic concentration. Hence, the distinction between these two metallic glasses lies in their most dominant element, namely Ca and Mg. These Ca-based bulk glassy alloys had compositions of CaMgZn, CaMgZn, and CaMgZn, where X = 0, 5 and 10; Y = 0, 5, 7.5, 10, and 15; and