Mammary gland gestation, serum progesterone remains at a stably high concentration so signaling through its receptor is continuously activated. As one of the transcribed genes, Wnts secreted from mammary epithelial cells act paracrinely to induce more neighboring cells' branching. When the lactiferous duct tree is almost ready, "leaves" alveoli are differentiated from luminal epithelial cells and added at the end of each branch. In late pregnancy and for the first few days after giving birth, colostrum is secreted. Milk secretion (lactation) begins a few days later due to reduction in circulating progesterone and the presence of another important hormone prolactin, which mediates
You Don't Know What Love Is (You Just Do as You're Told) Just Do as You're Told)" premiered on MTV2 Unleashed, as well as MTV.com and MTV2.com on July 30, 2007. The video was filmed in front of the Hudson's Bay Company historical buildings in the Apex neighborhood of Iqaluit, the capital of the northern Canadian territory of Nunavut, while the band was on tour there. Australian R&B singer-songwriter Daniel Merriweather covered the song as a bonus track for the Japanese edition of his 2009 album "Love & War". You Don't Know What Love Is (You Just Do as You're Told) "You Don't Know What Love Is (You Just Do as You're