Great Bustard Memorandum of Understanding for governments, scientists, conservation bodies and others to monitor and coordinate conservation efforts. These efforts need to focus on active habitat management and on maintaining large areas of non-intensive farming systems. The MoU only covers the middle-European populations of the great bustard ("Otis tarda"). Several remnant great bustard populations that can be found in, inter alia, Spain, Portugal, Morocco, Russia, Turkey, Kazakhstan, China and Mongolia are not included. All signatories shall endeavour to work closely together and with appropriate international organizations to improve the conservation status of the great bustard throughout its breeding, migratory and wintering range. Therefore, they shall:
Porphyria cutanea tarda the body. Certain mutations in the "HFE" gene cause hemochromatosis (an iron overload disorder). People who have these mutations are also at an increased risk of developing porphyria cutanea tarda. In the 20% of cases where porphyria cutanea tarda is inherited, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene is sufficient to decrease enzyme activity and cause the signs and symptoms of the disorder. While inherited deficiencies in uroporphyrinogen decarboxylase often lead to the development of PCT, there are a number of risk factors that can both cause and exacerbate the symptoms