Mammary gland gestation, serum progesterone remains at a stably high concentration so signaling through its receptor is continuously activated. As one of the transcribed genes, Wnts secreted from mammary epithelial cells act paracrinely to induce more neighboring cells' branching. When the lactiferous duct tree is almost ready, "leaves" alveoli are differentiated from luminal epithelial cells and added at the end of each branch. In late pregnancy and for the first few days after giving birth, colostrum is secreted. Milk secretion (lactation) begins a few days later due to reduction in circulating progesterone and the presence of another important hormone prolactin, which mediates
Niandra LaDes and Usually Just a T-Shirt album was] an intriguing and unexpected departure from Frusciante's work with the Chili Peppers", and that "the sparse arrangements of the first half help set the stage for the gossamer guitar work later on." He went on to say that "Usually Just a T-Shirt"—the latter half of the album—contained "pleasant psychedelic instrumentals with plenty of backward-guitar effects." Ned Raggett, also of AllMusic, noted that "there's nothing quite so stunning as [Frusciante's] magnificent remake of Bad Brains' 'The Big Takeover'." Adam Williams of PopMatters said the album "fall[s] somewhere between madness and brilliance". He went on to compare Frusciante to Syd