Radium chemicals and cause radioluminescence. Radium, in the form of radium chloride, was discovered by Marie and Pierre Curie in 1898. They extracted the radium compound from uraninite and published the discovery at the French Academy of Sciences five days later. Radium was isolated in its metallic state by Marie Curie and André-Louis Debierne through the electrolysis of radium chloride in 1911. In nature, radium is found in uranium and (to a lesser extent) thorium ores in trace amounts as small as a seventh of a gram per ton of uraninite. Radium is not necessary for living organisms, and adverse health
Radium-223 kBq/ml), sodium chloride, and other ingredients for intravenous injection. Algeta ASA was later acquired by Bayer who is now the sole owner of Xofigo. The recommended regimen is six treatments of 55 kBq/kg (1.3 uCi per kg), repeated at 4-week intervals. The use of radium-223 to treat metastatic bone cancer relies on the ability of alpha radiation from radium-223 and its short-lived decay products to kill cancer cells. Radium is preferentially absorbed by bone by virtue of its chemical similarity to calcium, with most radium-223 that is not taken up by the bone being cleared, primarily via the gut, and