Cholecystitis as choledocholithiasis. People who are old, have diabetes, chronic illness, or who are immunocompromised may have vague symptoms that may not include fever or localized tenderness. A number of complications may occur from cholecystitis if not detected early or properly treated. Signs of complications include high fever, shock and jaundice. Complications include the following: Cholecystitis causes the gallbladder to become distended and firm. Distension can lead to decreased blood flow to the gallbladder, causing tissue death and eventually gangrene. Once tissue has died, the gallbladder is at greatly increased risk of rupture (perforation). Rupture can also occur in cases of
The World Is What It Is The World Is What It Is The World Is What It Is: The Authorized Biography of V. S. Naipaul is a biography of the Nobel Prize-winning author V. S. Naipaul by Patrick French. It was published in 2008 (by Picador in the UK and Knopf in the USA). The title is a quotation from Naipaul's book "A Bend in the River". "The world is what it is; men who are nothing, who allow themselves to become nothing, have no place in it." French deals with Naipaul's family background and his life from his birth in 1932 until his second marriage