Radium bromide Institute had four grams of radium total, which at the time was more than half the world supply. Countries all over the world set out to make as much radium as possible, a time consuming and expensive task. It was reported in "Science" magazine in 1919 that the United States had produced approximately 55 grams of radium since 1913, which was also more than half the radium produced in the world at the time. A principal source for radium is pitchblende, which holds a total of 257 mg of radium per ton of UO. Obviously with so little product recovered
Radium-223 Radium-223 Radium-223 (Ra-223, Ra) is an isotope of radium with an 11.4-day half-life, in contrast to the more common isotope radium-226, discovered by the Curies, which has a 1601-year half-life. The principal use of radium-223, as a radiopharmaceutical to treat metastatic cancers in bone, takes advantage of its chemical similarity to calcium, and the short range of the alpha radiation it emits. Although radium-223 is formed naturally in trace amounts by the decay of uranium-235, it is generally made artificially, by exposing natural radium-226 to neutrons to produce radium-227, which decays with a 42-minute half-life to actinium-227. Actinium-227 (half-life 21.8