Radium seventh of a gram of radium. One kilogram of the Earth's crust contains about 900 picograms of radium, and one liter of sea water contains about 89 femtograms of radium. Radium was discovered by Marie Sklodowska-Curie and her husband Pierre Curie on 21 December 1898, in a uraninite (pitchblende) sample. While studying the mineral earlier, the Curies removed uranium from it and found that the remaining material was still radioactive. They separated out an element similar to bismuth from pitchblende in July 1898, that turned out to be polonium. They then separated out a radioactive mixture consisting mostly of two
Radium in the early 1900s are not used anymore because of the harmful effects radium bromide exposure caused. Some examples of these effects are anaemia, cancer, and genetic mutations. Safer gamma emitters such as Co, which is less costly and available in larger quantities, are usually used today to replace the historical use of radium in this application. Early in the 1900s, biologists used radium to induce mutations and study genetics. As early as 1904, Daniel MacDougal used radium in an attempt to determine whether it could provoke sudden large mutations and cause major evolutionary shifts. Thomas Hunt Morgan used radium