Group 12 element people in the 17th century. German chemist Andreas Marggraf is usually given credit for discovering pure metallic zinc in a 1746 experiment by heating a mixture of calamine and charcoal in a closed vessel without copper to obtain a metal. Experiments on frogs by the Italian doctor Luigi Galvani in 1780 with brass paved the way for the discovery of electrical batteries, galvanization and cathodic protection. In 1880, Galvani's friend, Alessandro Volta, invented the Voltaic pile. The biological importance of zinc was not discovered until 1940 when carbonic anhydrase, an enzyme that scrubs carbon dioxide from blood, was shown to
Metallic bonding are typically not molecular, Dalton's law of integral proportions is not valid and often a range of stoichiometric ratios can be achieved. It is better to abandon such concepts as 'pure substance' or 'solute' is such cases and speak of phases instead. The study of such phases has traditionally been more the domain of metallurgy than of chemistry, although the two fields overlap considerably. The metallic bonding in complicated compounds does not necessarily involve all constituent elements equally. It is quite possible to have an element or more that do not partake at all. One could picture the conduction electrons