Avogadro constant Avogadro constant In chemistry and physics, the Avogadro constant, named after scientist Amedeo Avogadro, is the number of constituent particles, usually atoms or molecules, that are contained in the amount of substance given by one mole. Thus, it is the proportionality factor that relates the molar mass of a substance to the mass of a sample. The Avogadro constant, often designated with the symbol "N" or "L", has the value in the International System of Units (SI). (The parentheses there represent the degree of uncertainty.) Previous definitions of chemical quantity involved the Avogadro number, a historical term closely related to
Amount of substance especially the early metallurgists, probably had some notion of amount of substance, but there are no surviving records of any generalization of the idea beyond a set of recipes. In 1758, Mikhail Lomonosov questioned the idea that mass was the only measure of the quantity of matter, but he did so only in relation to his theories on gravitation. The development of the concept of amount of substance was coincidental with, and vital to, the birth of modern chemistry. Amount of substance Amount of substance is a standard-defined quantity that measures the size of an ensemble of particles, such as