Mole (unit) Mole (unit) The mole is the unit of measurement for amount of substance in the International System of Units (SI). Effective 20 May 2019, the mole is defined as the amount of a chemical substance that contains exactly (Avogadro's constant) constitutive particles, e.g., atoms, molecules, ions or electrons. This definition was adopted in November of 2018, revising its old definition based on the number of atoms in 12 grams of carbon-12 (C) (the isotope of carbon with standard atomic weight 12 by definition). The mole is an SI base unit, with the unit symbol mol. The mole is widely used
Ground substance as hyaluronic acid, heparan sulfate, dermatan sulfate, and chondroitin sulfate, proteoglycans which GAGs are bound to, and glycoproteins. Components of the ground substance are secreted by fibroblasts. Usually it is not visible on slides, because it is lost during staining in the preparation process. Link proteins such as vinculin, spectrin and actomyosin stabilize the proteoglycans and organize elastic fibers in the ECM. Changes in the density of ground substance can allow collagen fibers to form aberrant cross-links. Loose connective tissue is characterized by few fibers and cells, and a relatively large amount of ground substance. Dense connective tissue has a