Great bustard Great bustard The great bustard ("Otis tarda") is a bird in the bustard family, the only member of the genus "Otis". It breeds in open grassland and farmland in southern and central Europe, and across temperate Asia. European populations are mainly resident, but Asian birds move farther south in winter. Portugal and Spain now have about 60% of the world's population. It became extinct in Great Britain when the last bird was shot in 1832. Recent attempts to reintroduce it into England have met with some success and there is a population of 40 birds on Salisbury Plain, a British
Porphyria cutanea tarda the body. Certain mutations in the "HFE" gene cause hemochromatosis (an iron overload disorder). People who have these mutations are also at an increased risk of developing porphyria cutanea tarda. In the 20% of cases where porphyria cutanea tarda is inherited, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene is sufficient to decrease enzyme activity and cause the signs and symptoms of the disorder. While inherited deficiencies in uroporphyrinogen decarboxylase often lead to the development of PCT, there are a number of risk factors that can both cause and exacerbate the symptoms