Animal mesoderm forms by enterocoelic pouching, through invagination of the endoderm. The main deuterostome phyla are the Echinodermata and the Chordata. Echinoderms are exclusively marine and include starfish, sea urchins, and sea cucumbers. The chordates are dominated by the vertebrates (animals with backbones), which consist of fishes, amphibians, reptiles, birds, and mammals. The deuterostomes also include the Hemichordata (acorn worms). The Ecdysozoa are protostomes, named after their shared trait of ecdysis, growth by moulting. They include the largest animal phylum, the Arthropoda, which contains insects, spiders, crabs, and their kin. All of these have a body divided into repeating segments, typically
Crown-of-thorns starfish disease marked by "discoloured and necrotic skin, ulcerations, loss of body turgor, accumulation of colourless mucus on many spines especially at their tip, and loss of spines. Blisters on the dorsal integument broke through the skin surface and resulted in large, open sores that exposed the internal organs." An autonomous starfish-killing robot called COTSBot has been developed and as of September 2015 was close to being ready for trials on the Great Barrier Reef. The COTSbot, which has a neural net-aided vision system, is designed to seek out crown-of-thorns starfish and give them a lethal injection of bile salts. After