Cholecystitis or scarring of the bile duct. The greatest risk factor for cholecystitis is gallstones. Risk factors for gallstones include female sex, increasing age, pregnancy, oral contraceptives, obesity, diabetes mellitus, ethnicity (Native North American), rapid weight loss. Gallstones blocking the flow of bile account for 90% of cases of cholecystitis (acute calculous cholecystitis). Blockage of bile flow leads to thickening and buildup of bile causing an enlarged, red, and tense gallbladder. The gallbladder is initially sterile but often becomes infected by bacteria, predominantly "E. coli", "Klebsiella", "Streptococcus", and "Clostridium" species. Inflammation can spread to the outer covering of the gallbladder and
History of beliefs about the human body the senses to identify what has gone wrong. The Ebers Papyrus refers to many god-like and spiritual infestations of the body that could not be explained at the time. Despite the explanations for maladies by spiritual rational, the interventions described to investigate and see the body were distinctly disconnected for the spirit or life force of the body and was principally about what could be seen or touched. Descriptions of the exact placement of the heart within the body, the circulation of blood are in no doubt accurate as Egyptians practiced embalming their dead by removal of organs and placement