Enzyme unit SI unit, the enzyme unit is discouraged in favour of the katal, the unit recommended by the General Conference on Weights and Measures in 1978 and officially adopted in 1999. One katal is the amount of enzyme that converts 1 mole of substrate per second, so The enzyme unit should not be confused with the international unit (IU); although it is true that both measure chemical activity and that for many enzymes 1 U = 1 IU (because for many enzymes the existing U was adopted as the newer IU), international units can be defined for the biologic activity of
Amount of substance especially the early metallurgists, probably had some notion of amount of substance, but there are no surviving records of any generalization of the idea beyond a set of recipes. In 1758, Mikhail Lomonosov questioned the idea that mass was the only measure of the quantity of matter, but he did so only in relation to his theories on gravitation. The development of the concept of amount of substance was coincidental with, and vital to, the birth of modern chemistry. Amount of substance Amount of substance is a standard-defined quantity that measures the size of an ensemble of particles, such as