Stepnoi Nature Sanctuary eagle ("Aquila heliaca"), demoiselle crane ("Grus virgo"), black-winged pratincole ("Glareola nordmanni"), little bustard ("Tetrax tetrax"), etc Stepnoi Nature Sanctuary Stepnoi State Nature Sanctuary (Russian: государственный природный заказник "Степной") (also Stepnoy Nature Reserve) is a protected area located in Liman district of Astrakhan Oblast, Russia. The sanctuary was declared in 2000 to ensure maintenance of unique natural complex of Stipa steppe providing habitat for saiga antelope ("Saiga tatarica tatarica") and a number of other endangered species of animals and plants. The sanctuary covers an area of 109.4 thousands of hectares. The monitoring program started in 2004 showed that the sanctuary is
Porphyria cutanea tarda the body. Certain mutations in the "HFE" gene cause hemochromatosis (an iron overload disorder). People who have these mutations are also at an increased risk of developing porphyria cutanea tarda. In the 20% of cases where porphyria cutanea tarda is inherited, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene is sufficient to decrease enzyme activity and cause the signs and symptoms of the disorder. While inherited deficiencies in uroporphyrinogen decarboxylase often lead to the development of PCT, there are a number of risk factors that can both cause and exacerbate the symptoms