Calamine the World Health Organization's List of Essential Medicines for being one of the most effective and safe medicines needed in a health system. Calamine is available over the counter as a generic medication. The wholesale cost in the developing world is about US$0.25–3.85 per 100-ml bottle. In the United Kingdom, it costs the National Health Service about £0.44. Calamine is used to treat itchiness. This includes from sunburn, insect bite, or other mild skin conditions. Calamine is mixed with either zinc oxide (ZnO) with about 0.5% ferric oxide (FeO) or a zinc carbonate compound. Calamine lotion is a component of
Calamine brass company (within whose monopoly it was) to build a brass works at Isleworth. However a decade later the company obstructed the owners from mining calamine. A plaque at Tintern Abbey claims that the well-known brassworks at this site began in 1568. New brass works were built by Jacob Momma, a German immigrant in 1649 at Esher, probably using Swedish copper. After the passing of the Mines Royal Act in 1689, further works were built near Bristol, where brass production became a major industry in the 18th century. Later brass production sites in England included Cheadle and Birmingham. Calamine brass was