Zolotnik Zolotnik A zolotnik (in Russian: золотни́к; abbr.: zol.) was a small Russian unit of weight, equal to 0.1505 avoirdupois ounces, or 4.2658 grams (about 65.83 grains). Used from the 10th to 20th centuries, its name is derived from the Russian word "zoloto", meaning gold. As a unit, the zolotnik was the standard for silver manufacture, much as the troy ounce is currently used for gold and other precious metals. This unit was originally based on a coin of the same name. The zolotnik circulated in the Kievan Rus until the 11th century; it was equal in weight to the Byzantine
Metals in medicine have been used in treatments since ancient times. The Ebers Papyrus from 1500BC is the first written account of the use of metals for treatment and describes the use of Copper to reduce inflammation and the use of iron to treat anemia. Sodium vanadate has been used since the early 20th century to treat rheumatoid arthritis. Recently metals have been used to treat cancer, by specifically attacking cancer cells and interacting directly with DNA. The positive charge on most metals can interact with the negative charge of the phosphate backbone of DNA. Some drugs developed that include metals interact directly