Mammary gland gestation, serum progesterone remains at a stably high concentration so signaling through its receptor is continuously activated. As one of the transcribed genes, Wnts secreted from mammary epithelial cells act paracrinely to induce more neighboring cells' branching. When the lactiferous duct tree is almost ready, "leaves" alveoli are differentiated from luminal epithelial cells and added at the end of each branch. In late pregnancy and for the first few days after giving birth, colostrum is secreted. Milk secretion (lactation) begins a few days later due to reduction in circulating progesterone and the presence of another important hormone prolactin, which mediates
Milk & Sugar Milk & Sugar Milk & Sugar are German house music producers and record label owners (based in Munich) Mike Milk (real name, Michael Kronenberger) and Steven Sugar (real name, Steffen Harding). The two have collaborated since 1993 under a variety of names, including Axis, Hitch Hiker & Jacques Dumondt, and Mike Stone & Steve Heller, and have scored major club hits internationally, including a re-make of John Paul Young's "Love Is in the Air". Influenced in the mid 1990s by Spain discohouse movement, Kronenberger (aka Milk) and Harding (aka Sugar) teamed up as a DJ and producer duo, creating Milk