Cholecystitis or scarring of the bile duct. The greatest risk factor for cholecystitis is gallstones. Risk factors for gallstones include female sex, increasing age, pregnancy, oral contraceptives, obesity, diabetes mellitus, ethnicity (Native North American), rapid weight loss. Gallstones blocking the flow of bile account for 90% of cases of cholecystitis (acute calculous cholecystitis). Blockage of bile flow leads to thickening and buildup of bile causing an enlarged, red, and tense gallbladder. The gallbladder is initially sterile but often becomes infected by bacteria, predominantly "E. coli", "Klebsiella", "Streptococcus", and "Clostridium" species. Inflammation can spread to the outer covering of the gallbladder and
Body part as an object 1963 article, and the results replicated by Overton & Jackson. Their findings suggest younger children were more likely to use BPO pantomimes to create a tangible representation of the object they were pantomiming. Boyatzis & Watson suggests that the decrease in BPO pantomime usage with age is a result of developing symbolic maturity, as older children can use a less concrete representational form. Body part as object errors are defined as the use of BPO pantomimes in place of the IO pantomimes dominant in typical adult individuals. It has been debated whether the existence of BPO errors can be used