Eremopezus more than a large emu—and more than 10 kg—slightly more than the largest living storks (which reach over 150 cm in height) and the shoebill. The general limit for weight in flying birds is at about 25 kg, the exceptional "Argentavis magnificens" with its size and weight of a good-sized adult human notwithstanding as it evolved under unusual ecological conditions. Large males of the kori bustard ("Ardeotis kori") and great bustard ("Otis tarda") are perfectly capable of flight, while weighing in excess of 20 kg. A wing loading of c. 25 kg/m is the known limit for bird flight under
Porphyria cutanea tarda the body. Certain mutations in the "HFE" gene cause hemochromatosis (an iron overload disorder). People who have these mutations are also at an increased risk of developing porphyria cutanea tarda. In the 20% of cases where porphyria cutanea tarda is inherited, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene is sufficient to decrease enzyme activity and cause the signs and symptoms of the disorder. While inherited deficiencies in uroporphyrinogen decarboxylase often lead to the development of PCT, there are a number of risk factors that can both cause and exacerbate the symptoms