Calamine the World Health Organization's List of Essential Medicines for being one of the most effective and safe medicines needed in a health system. Calamine is available over the counter as a generic medication. The wholesale cost in the developing world is about US$0.25–3.85 per 100-ml bottle. In the United Kingdom, it costs the National Health Service about £0.44. Calamine is used to treat itchiness. This includes from sunburn, insect bite, or other mild skin conditions. Calamine is mixed with either zinc oxide (ZnO) with about 0.5% ferric oxide (FeO) or a zinc carbonate compound. Calamine lotion is a component of
Ore Mountains last silver mines closed and the company was disbanded. Mining in the Ore Mountains was given new life during the First and Second World Wars in order to supply raw materials. The Third Reich also saw the resumption of silver mining. Afterwards the people returned to the manufacture of wooden products and toys, especially in the Eastern Ore Mountains. The clock industry is centred on Glashütte. In the Western Ore Mountains, economic alternatives were offered by the engineering and textile industries. In 1789 the chemical element uranium was discovered in St. Joachimsthal; then in pitchblende from the same area, radium