Mammary gland gestation, serum progesterone remains at a stably high concentration so signaling through its receptor is continuously activated. As one of the transcribed genes, Wnts secreted from mammary epithelial cells act paracrinely to induce more neighboring cells' branching. When the lactiferous duct tree is almost ready, "leaves" alveoli are differentiated from luminal epithelial cells and added at the end of each branch. In late pregnancy and for the first few days after giving birth, colostrum is secreted. Milk secretion (lactation) begins a few days later due to reduction in circulating progesterone and the presence of another important hormone prolactin, which mediates
Beauty (Neutral Milk Hotel album) Beauty (Neutral Milk Hotel album) Beauty is the second demo recorded by Neutral Milk Hotel, recorded in 1992, released on a cassette tape. All songs written by Jeff Mangum except where noted. Said to be from 1992. As with "Invent Yourself a Shortcake", it's debatable whether this cassette is an actual "album" or just a collection of recordings Jeff put together. No original physical copy is known to exist. It is possible that Jeff put this tape together for friends and it wound up online. The first five tracks are solo acoustic with Jeff talking a little bit before and