Avogadro constant of molecules in one gram-molecule of oxygen (exactly of oxygen, according to the definitions of the period), and this term is still widely used, especially in introductory works. The change in name to "Avogadro constant" ("N") came with the introduction of the mole as a base unit in the International System of Units (SI) in 1971, which regarded amount of substance as an independent dimension of measurement. With this recognition, the Avogadro constant was no longer a pure number, but had a unit of measurement, the reciprocal mole (mol). While it is rare to use units of amount of substance
Amount of substance especially the early metallurgists, probably had some notion of amount of substance, but there are no surviving records of any generalization of the idea beyond a set of recipes. In 1758, Mikhail Lomonosov questioned the idea that mass was the only measure of the quantity of matter, but he did so only in relation to his theories on gravitation. The development of the concept of amount of substance was coincidental with, and vital to, the birth of modern chemistry. Amount of substance Amount of substance is a standard-defined quantity that measures the size of an ensemble of particles, such as