Group 12 element people in the 17th century. German chemist Andreas Marggraf is usually given credit for discovering pure metallic zinc in a 1746 experiment by heating a mixture of calamine and charcoal in a closed vessel without copper to obtain a metal. Experiments on frogs by the Italian doctor Luigi Galvani in 1780 with brass paved the way for the discovery of electrical batteries, galvanization and cathodic protection. In 1880, Galvani's friend, Alessandro Volta, invented the Voltaic pile. The biological importance of zinc was not discovered until 1940 when carbonic anhydrase, an enzyme that scrubs carbon dioxide from blood, was shown to
Group 5 element magnesium. 230,000 metric tons of niobium ore are produced yearly, with Brazil producing metric 210,000 tons, Canada producing 10000 metric tons, and Australia producing 1000 metric tons. 60000 metric tons of pure niobium are produced each year. 70000 metric tons of tantalum ore are produced yearly. Brazil produces 90% of tantalum ore, with Canada, Australia, China, and Rwanda also producing the element. The demand for tantalum is around 1200 metric tons per year. Dubnium is produced synthetically by bombarding actinides with lighter elements. Vanadium's main application is in alloys, such as vanadium steel. Vanadium alloys are used in springs, tools,