Carbolic soap Carbolic soap Carbolic soap is a mildly antiseptic soap containing carbolic acid and/or cresylic acid, both of which are phenols derived from either coal tar or petroleum sources. In 1834, German chemist Friedlieb Ferdinand Runge discovered a phenol, now known as carbolic acid, which he derived in an impure form from coal tar. In August 1865, Dr. Joseph Lister, 1st Baron Lister applied a piece of lint dipped in carbolic acid solution onto the wound of an eleven-year-old boy at Glasgow Royal Infirmary, who had sustained a compound fracture after a cart wheel had passed over his leg. After four
Aminoshikimic acid Aminoshikimic acid is an intriguing alternative to shikimic acid as a starting material for the synthesis of neuraminidase inhibitors such as the antiinfluenza agent oseltamivir. Aminoshikimic acid is also a versatile chiral starting material for the synthesis of new pharmaceuticals. As with shikimic acid, aminoshikimic acid is an attractive candidate for use as the core scaffold for synthesis of combinatorial libraries. Aminoshikimic acid Aminoshikimic acid is a synthetic crystalline carboxylic acid. It is characterized by multiple stereogenic centers and functional groups arrayed around a six-membered carbocyclic ring. Aminoshikimic acid is also an alternative to shikimic acid as a starting material