Mole (unit) in chemistry as a convenient way to express amounts of reactants and products of chemical reactions. For example, the chemical equation can be interpreted to mean that 2 mol dihydrogen (H) and 1 mol dioxygen (O) react to form 2 mol water (HO). The mole may also be used to represent the number of atoms, ions, or other entities in a given sample of a substance. The concentration of a solution is commonly expressed by its molarity, defined as the amount of dissolved substance per unit volume of solution, for which the unit typically used is moles per litre (mol/l).
Amount of substance especially the early metallurgists, probably had some notion of amount of substance, but there are no surviving records of any generalization of the idea beyond a set of recipes. In 1758, Mikhail Lomonosov questioned the idea that mass was the only measure of the quantity of matter, but he did so only in relation to his theories on gravitation. The development of the concept of amount of substance was coincidental with, and vital to, the birth of modern chemistry. Amount of substance Amount of substance is a standard-defined quantity that measures the size of an ensemble of particles, such as