Great Bustard Memorandum of Understanding Herzegovina, Bulgaria, Croatia, Czech Republic, European Union, Germany, Greece, Hungary, Moldova, Poland, Romania, Slovakia, Slovenia, The Republic of Macedonia and Ukraine). As of August 2012, 13 range states have signed the MoU as well as a number of cooperating organizations. To implement the decision of the Fourth Conference of the Parties of CMS to list the great bustard ("Otis tarda") on Appendix II of the Convention as a consequence of its unfavourable conservation status and the conviction that the species could benefit from an international agreement for its conservation and management and the middle-European population on Appendix I of the
Porphyria cutanea tarda because of liver toxicity. Finally, due to the strong association between PCT and Hepatitis C, the treatment of Hepatitis C (if present) is vital to the effective treatment of PCT. Chloroquine, hydroxychloroquine, and venesection are typically employed in the management strategy. Porphyria cutanea tarda has a prevalence estimated at approximately 1 in 10,000. An estimated 80% of porphyria cutanea tarda cases are sporadic. The exact frequency is not clear because many people with the condition never experience symptoms and those that do are often misdiagnosed with anything ranging from idiopathic photodermatitis and seasonal allergies to hives. Porphyria cutanea tarda is