Mammary gland gestation, serum progesterone remains at a stably high concentration so signaling through its receptor is continuously activated. As one of the transcribed genes, Wnts secreted from mammary epithelial cells act paracrinely to induce more neighboring cells' branching. When the lactiferous duct tree is almost ready, "leaves" alveoli are differentiated from luminal epithelial cells and added at the end of each branch. In late pregnancy and for the first few days after giving birth, colostrum is secreted. Milk secretion (lactation) begins a few days later due to reduction in circulating progesterone and the presence of another important hormone prolactin, which mediates
From What Is Before score of 100% rating based on 5 critics. From What Is Before From What Is Before () is a 2014 Filipino drama film directed by Lav Diaz. The film follows a remote town in the Philippines during the 1970s under the Marcos dictatorship. The film had its world premiere in the Philippines on 3 July 2014, and competed at the 2014 Locarno International Film Festival where it won the main prize, the Golden Leopard. The film also had its North American premiere at the 2014 Toronto International Film Festival, under the Wavelengths section. In addition, the film had its Philippine