Mark (unit) Mark (unit) The Mark (from Middle High German: Marc, march, brand) is originally a medieval weight or mass unit, which supplanted the pound weight as a precious metals and coinage weight from the 11th century. The Mark is traditionally a half pound weight and was usually divided into 8 ounces or 16 Lot. The significance of the "Cologne Mark" (Kölner Mark) in the German-speaking areas corresponded to about 234 gram. Like the German systems, the French poids de marc weight system considered one "Marc" equal to half-a-pound (8 ounces). Like the pound of 12 troy ounces (373 g), the mark
Metals in medicine have been used in treatments since ancient times. The Ebers Papyrus from 1500BC is the first written account of the use of metals for treatment and describes the use of Copper to reduce inflammation and the use of iron to treat anemia. Sodium vanadate has been used since the early 20th century to treat rheumatoid arthritis. Recently metals have been used to treat cancer, by specifically attacking cancer cells and interacting directly with DNA. The positive charge on most metals can interact with the negative charge of the phosphate backbone of DNA. Some drugs developed that include metals interact directly