Mammary gland gestation, serum progesterone remains at a stably high concentration so signaling through its receptor is continuously activated. As one of the transcribed genes, Wnts secreted from mammary epithelial cells act paracrinely to induce more neighboring cells' branching. When the lactiferous duct tree is almost ready, "leaves" alveoli are differentiated from luminal epithelial cells and added at the end of each branch. In late pregnancy and for the first few days after giving birth, colostrum is secreted. Milk secretion (lactation) begins a few days later due to reduction in circulating progesterone and the presence of another important hormone prolactin, which mediates
What You See Is What You Get (book) What You See Is What You Get (book) What You See Is What You Get is the autobiography of British businessman and TV personality Lord Alan Sugar. The 640-page book, which was published in May 2011, tells the story of Alan Sugar's birth and childhood in a deprived part of London, how he founded the company Amstrad aged just 21 years old, and how he eventually became a successful multi-millionaire tycoon, received a knighthood, and was appointed to the House of Lords. Sir Alan also reveals his main method of business and entrepreneurial activity: (a) observing what market leaders are