Cholecystitis or scarring of the bile duct. The greatest risk factor for cholecystitis is gallstones. Risk factors for gallstones include female sex, increasing age, pregnancy, oral contraceptives, obesity, diabetes mellitus, ethnicity (Native North American), rapid weight loss. Gallstones blocking the flow of bile account for 90% of cases of cholecystitis (acute calculous cholecystitis). Blockage of bile flow leads to thickening and buildup of bile causing an enlarged, red, and tense gallbladder. The gallbladder is initially sterile but often becomes infected by bacteria, predominantly "E. coli", "Klebsiella", "Streptococcus", and "Clostridium" species. Inflammation can spread to the outer covering of the gallbladder and
What Is Mathematics? What Is Mathematics? What Is Mathematics? is a mathematics book written by Richard Courant and Herbert Robbins, published in England by Oxford University Press. It is an introduction to mathematics, intended both for the mathematics student and for the general public. First published in 1941, it discusses number theory, geometry, topology and calculus. A second edition was published in 1996 with an additional chapter on recent progress in mathematics, written by Ian Stewart. The book was based on Courant's course material. Although Robbins assisted in writing a large part of the book, he had to fight for authorship. Nevertheless, Courant