Colostrum Colostrum Colostrum (known colloquially as beestings, bisnings or first milk) is the first form of milk produced by the mammary glands of mammals (including many humans) immediately following delivery of the newborn. Most species will generate colostrum just prior to giving birth. Colostrum contains antibodies to protect the newborn against disease. In general, protein concentration in colostrum is substantially higher than in milk. Fat concentration is substantially higher in colostrum than in milk in some species, e.g. sheep and horses, but lower in colostrum than in milk in some other species, e.g. camels and humans. In swine, fat concentration of
Secreted frizzled-related protein 1 to interact with FZD6. Secreted frizzled-related protein 1 Secreted frizzled-related protein 1, also known as SFRP1, is a protein which in humans is encoded by the "SFRP1" gene. Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in the heart. The Secreted frizzled-related protein (SFRP) family consists of