Frances Villiers, Countess of Jersey his "wife", Maria Fitzherbert, with whom he had undergone a form of marriage in a clandestine Church of England ceremony that all parties to it knew was invalid under the Royal Marriages Act 1772. Having encouraged the Prince of Wales to marry his first cousin, Caroline of Brunswick in 1794, Lady Jersey nevertheless set out to make Caroline's life difficult. However, the now Princess of Wales (Caroline) had very little regard for George IV, nor he for her, and after the birth of their child, they lived apart during their twenty-five year marriage, leaving a void Frances and other mistresses,
19th century in science 19th century in science The 19th century in science saw the birth of science as a profession; the term scientist was coined in 1833 by William Whewell, which soon replaced the older term of (natural) philosopher. Among the most influential ideas of the 19th century were those of Charles Darwin (alongside the independent researches of Alfred Russel Wallace), who in 1859 published the book "The Origin of Species", which introduced the idea of evolution by natural selection. Another important landmark in medicine and biology were the successful efforts to prove the germ theory of disease. Following this, Louis Pasteur made