Mammary gland gestation, serum progesterone remains at a stably high concentration so signaling through its receptor is continuously activated. As one of the transcribed genes, Wnts secreted from mammary epithelial cells act paracrinely to induce more neighboring cells' branching. When the lactiferous duct tree is almost ready, "leaves" alveoli are differentiated from luminal epithelial cells and added at the end of each branch. In late pregnancy and for the first few days after giving birth, colostrum is secreted. Milk secretion (lactation) begins a few days later due to reduction in circulating progesterone and the presence of another important hormone prolactin, which mediates
Ain't It Funny What a Difference Just a Few Hours Make known as Billy Murray is downloadable at several websites. His version was released by Victor Records. Ain't It Funny What a Difference Just a Few Hours Make "Ain't It Funny What a Difference Just a Few Hours Make" is a popular song, introduced in the 1904 Broadway show "The Yankee Consul", and briefly becoming a standard. The song is a lament by Abijah Booze, the American Consul in Puerto Plata, who regrets having to rise early. Booze's role in the premier was played by Raymond Hitchcock, his first starring role. The title is a refrain found throughout the song: Although