Stomach or compound racemose resembling the duodenal Brunner's glands The "fundic glands", are found in the fundus and body of the stomach. They are simple almost straight tubes, two or more of which open into a single duct. They secrete hydrochloric acid (HCl) and intrinsic factor. The "pyloric glands" are located in the antrum of the pylorus. They secrete gastrin produced by their G cells. About 20,000 protein coding genes are expressed in human cells and nearly 70% of these genes are expressed in the normal stomach. Just over 150 of these genes are more specifically expressed in the stomach compared
Cholic acid in bile acid synthesis), and cholesterol does the opposite. This is why chenodeoxycholic acid, and not cholic acid, can be used to treat gallstones (because decreasing bile acid synthesis would supersaturate the stones even more). Cholic acid and chenodeoxycholic acid are the most important human bile acids. Other species may synthesize different bile acids as their predominant primary bile acids. Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid synthesis disorders due to single enzyme defects, and for peroxisomal disorders (such as Zellweger