Hydrochloric acid enzyme pepsin by self-cleavage. After leaving the stomach, the hydrochloric acid of the chyme is neutralized in the duodenum by sodium bicarbonate. The stomach itself is protected from the strong acid by the secretion of a thick mucus layer, and by secretin induced buffering with sodium bicarbonate. Heartburn or peptic ulcers can develop when these mechanisms fail. Drugs of the antihistaminic and proton pump inhibitor classes can inhibit the production of acid in the stomach, and antacids are used to neutralize excessive existing acid. Concentrated hydrochloric acid (fuming hydrochloric acid) forms acidic mists. Both the mist and the solution have
What It Comes Down To What It Comes Down To "What It Comes Down To" is a song by The Isley Brothers, who released it in late 1973 as a follow-up to the group's crossover pop hit, "That Lady, Pt. 1 & 2". Both songs were featured on the group's Epic debut, "3 + 3". It features a synthesizer keyboard solo from Chris Jasper, Ernie Isley on guitar and Ronald Isley on lead vocals. The b-side of the song was the ballad "The Highways Of My Life". The song peaked at number 55 on the "Billboard" Hot 100 and was a top five hit on