Magnesium aspartate salts of magnesium have the greatest water solubility and demonstrate a greater oral absorption and bioavailability compared to less soluble magnesium preparations such as magnesium oxide, magnesium hydroxide, magnesium carbonate and magnesium sulphate. Magnesium-L-aspartate 1230 mg (magnesium 122 mg) up to 3 times/day Dosage adjustment in renal impairment: Patients with severe renal failure should not receive magnesium due to toxicity from accumulation. Magnesium supplements and other magnesium containing products, such as antacids, can bind with prescription medicines, reducing their effectiveness. Aspartate and glutamate are excitatory neurotransmitters. At high doses (consumed either independently or in excess of other protein–containing foods), can
Hydrated silica an odourless, tasteless, white, gelatinous substance, which is chemically inert. Chemical Formula: SiO · HO Diatomaceous earth, originally mined as "tooth powder" is a naturally occurring hydrated silica. As a fine gel abrasive, frequently combined with softer calcium carbonate (from chalk) it helps to remove plaque. Milled to a slightly larger size, the grains are more aggressive and are used in tooth bleaching formulations. It also has synergetic effects when compounded with traditional flame retardants such as magnesium hydroxide and aluminium hydroxide. Hydrated silica is listed by the US Food and Drug Administration as "Generally Recognized as Safe". Toothpaste: Chemistry: