Ruta graveolens the isolation of the furanocoumarin chalepensin. The essential oil of "R. graveolens" contains two main constituents, undecan-2-one (46.8%) and nonan-2-one (18.8%). The bitter taste of its leaves led to rue being associated with the (etymologically unrelated) verb "rue" "to regret". Rue is well known for its symbolic meaning of regret and it has sometimes been called "herb-of-grace" in literary works. It is one of the flowers distributed by the mad Ophelia in William Shakespeare's "Hamlet" (IV.5): It was planted by the gardener in "Richard II" to mark the spot where the Queen wept upon hearing news of Richard's capture (III.4.104–105):
Ophelia (painting) Ophelia (painting) Ophelia is a painting by British artist Sir John Everett Millais, completed in 1851 and 1852 and in the collection of Tate Britain in London. It depicts Ophelia, a character from William Shakespeare's play "Hamlet", singing before she drowns in a river in Denmark. The work encountered a mixed response when first exhibited at the Royal Academy, but has since come to be admired as one of the most important works of the mid-nineteenth century for its beauty, its accurate depiction of a natural landscape, and its influence on artists from John William Waterhouse and Salvador Dalí to