Ruta graveolens the isolation of the furanocoumarin chalepensin. The essential oil of "R. graveolens" contains two main constituents, undecan-2-one (46.8%) and nonan-2-one (18.8%). The bitter taste of its leaves led to rue being associated with the (etymologically unrelated) verb "rue" "to regret". Rue is well known for its symbolic meaning of regret and it has sometimes been called "herb-of-grace" in literary works. It is one of the flowers distributed by the mad Ophelia in William Shakespeare's "Hamlet" (IV.5): It was planted by the gardener in "Richard II" to mark the spot where the Queen wept upon hearing news of Richard's capture (III.4.104–105):
Ophelia (painting) Peter Blake (artist) and Ed Ruscha. The painting depicts Ophelia singing while floating in a river just before she drowns. The scene is described in Act IV, Scene VII of "Hamlet" in a speech by Queen Gertrude. The episode depicted is not usually seen onstage, as in Shakespeare's text it exists only in Gertrude's description. Out of her mind with grief, Ophelia has been making garlands of wildflowers. She climbs into a willow tree overhanging a brook to dangle some from its branches, and a bough breaks beneath her. She lies in the water singing songs, as if unaware of