Magnesium in biology be used as adjuvant therapy in patients on optimal treatment for severe congestive heart failure, increasing survival rate and improving clinical symptoms and patient's quality of life. Magnesium can affect muscle relaxation through direct action on cell membranes. Mg ions close certain types of calcium channels, which conduct positively charged calcium ions into neurons. With an excess of magnesium, more channels will be blocked and nerve cells activity will decrease. Intravenous magnesium sulphate is used in treating pre-eclampsia. For other than pregnancy-related hypertension, a meta-analysis of 22 clinical trials with dose ranges of 120 to 973 mg/day and a mean
Magnesium perchlorate Magnesium perchlorate Magnesium perchlorate is a powerful oxidizing agent, with the formula Mg(ClO). It is also a superior drying agent for gas analysis. Magnesium perchlorate decomposes at 250 °C. The heat of formation is -568.90 kJ mol. The enthalpy of solution is quite high, so reactions are done in large amounts of water to dilute it. It is sold under the trade name anhydrone. Manufacture of this product on a semi-industrial scale was first performed by G. Frederick Smith in his garage in Urbana Illinois, but later at a permanent facility in Columbus, OH called G. Frederick Smith Chemical Co.