Manganese is also used in portland cement mixtures. Manganese is an important element for human health, essential for development, metabolism, and the antioxidant system. Nevertheless, excessive exposure or intake may lead to a condition known as manganism, a neurodegenerative disorder that causes dopaminergic neuronal death and symptoms similar to Parkinson's disease. The classes of enzymes that have manganese cofactors is large and includes oxidoreductases, transferases, hydrolases, lyases, isomerases, ligases, lectins, and integrins. The reverse transcriptases of many retroviruses (though not lentiviruses such as HIV) contain manganese. The best-known manganese-containing polypeptides may be arginase, the diphtheria toxin, and Mn-containing superoxide dismutase (Mn-SOD).
Manganese(III) acetate Manganese(III) acetate Manganese(III) acetate describes a family of coordination complexes with the approximate formula Mn(OCCH). All are brown solids, which are soluble in acetic acid and water. These compounds are used in organic synthesis as oxidizing agents. Compounds with the formula Mn(OCCH) have not been verified. Instead manganese(III) acetate adopts the structure reminiscent of those of basic chromium acetate and basic iron acetate. For this reason, manganese(III) acetate is sometimes referred to as basic manganese acetate. The formula is [MnO(OCCH)L]X where L is a ligand and X is an anion. The coordination polymer [MnO(OCCH)]OCCHHOCCH has been crystallized. It is usually