Ruta graveolens the isolation of the furanocoumarin chalepensin. The essential oil of "R. graveolens" contains two main constituents, undecan-2-one (46.8%) and nonan-2-one (18.8%). The bitter taste of its leaves led to rue being associated with the (etymologically unrelated) verb "rue" "to regret". Rue is well known for its symbolic meaning of regret and it has sometimes been called "herb-of-grace" in literary works. It is one of the flowers distributed by the mad Ophelia in William Shakespeare's "Hamlet" (IV.5): It was planted by the gardener in "Richard II" to mark the spot where the Queen wept upon hearing news of Richard's capture (III.4.104–105):
Literary influence of Hamlet and Simple Murders"—in which the title character sets her son straight about Old Hamlet's murder: "It wasn't Claudius, darling, it was me!" Also, because of the criticism of the sexism, American author Lisa Klein wrote "Ophelia", a novel that portrays Ophelia, too, as feigning madness and surviving. Author Molly Booth has written a Young Adult historical fiction novel, "Saving Hamlet", about a teenage girl who time travels back to the original production of "Hamlet" at Shakespeare's Globe Theatre in London, 1601. The book has a focus on Ophelia's role, and how the sexism from Shakespeare's era translates to sexism in