Manganese 50 µg Mn/L. A protein called DMT1 is the major transporter in manganese absorption from the intestine, and may be the major transporter of manganese across the blood–brain barrier. DMT1 also transports inhaled manganese across the nasal epithelium. The proposed mechanism for manganese toxicity is that dysregulation leads to oxidative stress, mitochondrial dysfunction, glutamate-mediated excitoxicity, and aggregation of proteins. Manganese Manganese is a chemical element with symbol Mn and atomic number 25. It is not found as a free element in nature; it is often found in minerals in combination with iron. Manganese is a metal with important industrial metal
Manganese(II) carbonate to give water-soluble salts. Manganese carbonate decomposes with release of carbon dioxide, i.e. calcining, at 200 °C to give MnO: This method is sometimes employed in the production of manganese dioxide, which is used in dry-cell batteries and for ferrites. Manganese carbonate is widely used as an additive to plant fertilizers to cure manganese deficient crops. It is also used in health foods, in ceramics as a glaze colorant and flux, and in concrete stains. It is used in medicine as a hematinic. Manganese poisoning, also known as manganism, may be caused by long-term exposure to manganese dust or fumes.