Stomach or compound racemose resembling the duodenal Brunner's glands The "fundic glands", are found in the fundus and body of the stomach. They are simple almost straight tubes, two or more of which open into a single duct. They secrete hydrochloric acid (HCl) and intrinsic factor. The "pyloric glands" are located in the antrum of the pylorus. They secrete gastrin produced by their G cells. About 20,000 protein coding genes are expressed in human cells and nearly 70% of these genes are expressed in the normal stomach. Just over 150 of these genes are more specifically expressed in the stomach compared
Hydrochloric acid and acidifies the stomach content to a pH of 1 to 2. Chloride (Cl) and hydrogen (H) ions are secreted separately in the stomach fundus region at the top of the stomach by parietal cells of the gastric mucosa into a secretory network called canaliculi before it enters the stomach lumen. Gastric acid acts as a barrier against microorganisms to prevent infections and is important for the digestion of food. Its low pH denatures proteins and thereby makes them susceptible to degradation by digestive enzymes such as pepsin. The low pH also activates the enzyme precursor pepsinogen into the active