Gastric acid network (called canaliculi) from which the hydrochloric acid is secreted into the lumen of the stomach. The pH of gastric acid is 1.5 to 3.5 in the human stomach lumen, the acidity being maintained by the proton pump H/K ATPase. The parietal cell releases bicarbonate into the bloodstream in the process, which causes a temporary rise of pH in the blood, known as an alkaline tide. The highly acidic environment in the stomach lumen causes proteins from food to lose their characteristic folded structure (or denature). This exposes the protein's peptide bonds. The gastric chief cells of the stomach secrete
What Kate Does reviews"; however, this was down significantly from the previous episode's 89 and Bonnie Covel of About.com noted that " 'What Kate Does' brought us a bit of negativity. In general, fans just didn't like the episode". "What Kate Does" was largely considered to be a step down from the season premiere in pacing, revelations and writing; Mike Hale of "The New York Times" described the episode as "contemplative", "anticlimactic" and "subdued" and the flash sideways as "kind of boring and seemingly pointless." Chris Carabott of IGN, who gave the episode a score of 7.3 summed up that " 'What Kate