Manganese 50 µg Mn/L. A protein called DMT1 is the major transporter in manganese absorption from the intestine, and may be the major transporter of manganese across the blood–brain barrier. DMT1 also transports inhaled manganese across the nasal epithelium. The proposed mechanism for manganese toxicity is that dysregulation leads to oxidative stress, mitochondrial dysfunction, glutamate-mediated excitoxicity, and aggregation of proteins. Manganese Manganese is a chemical element with symbol Mn and atomic number 25. It is not found as a free element in nature; it is often found in minerals in combination with iron. Manganese is a metal with important industrial metal
Manganese(II) carbonate Manganese(II) carbonate Manganese carbonate is a compound with the chemical formula MnCO. Manganese carbonate occurs naturally as the mineral rhodochrosite but it is typically produced industrially. It is a pale pink, water-insoluble solid. Approximately 20,000 metric tonnes were produced in 2005. MnCO adopts a structure like calcite, consisting of manganese(II) ions in an octahedral coordination geometry. Treatment of aqueous solutions of manganese(II) nitrate with ammonia and carbon dioxide leads to precipitation of this faintly pink solid. The side product, ammonium nitrate is used as fertilizer. The carbonate is insoluble in water but, like most carbonates, hydrolyses upon treatment with acids