Magnesium in biology be used as adjuvant therapy in patients on optimal treatment for severe congestive heart failure, increasing survival rate and improving clinical symptoms and patient's quality of life. Magnesium can affect muscle relaxation through direct action on cell membranes. Mg ions close certain types of calcium channels, which conduct positively charged calcium ions into neurons. With an excess of magnesium, more channels will be blocked and nerve cells activity will decrease. Intravenous magnesium sulphate is used in treating pre-eclampsia. For other than pregnancy-related hypertension, a meta-analysis of 22 clinical trials with dose ranges of 120 to 973 mg/day and a mean
Magnesium hydroxide effects through the inclusion of aluminum hydroxide, which inhibits the contractions of smooth muscle cells in the gastrointestinal tract, thereby counterbalancing the contractions induced by the osmotic effects of the magnesium hydroxide. Magnesium hydroxide is also a component of antiperspirant. Magnesium hydroxide is useful against canker sores (aphthous ulcer) when used topically. Magnesium hydroxide powder is used industrially to neutralize acidic wastewaters. It also takes part in the Biorock method of building artificial reefs. Natural magnesium hydroxide (brucite) is used commercially as a fire retardant. Most industrially used magnesium hydroxide is produced synthetically. Like aluminium hydroxide, solid magnesium hydroxide has