Sleeping Beauty (franchise) such as the "Sleeping Beauty" characters. Characters from "Sleeping Beauty" also make minor appearances in the direct-to-video films based in the show, "" and "Mickey's House of Villains". Fantasy television series "Once Upon a Time" regularly include live-action interpretations of characters including Maleficent, Aurora, Phillip, King Stefan, and Aurora's mother is mentioned as Briar Rose, the "original" Sleeping Beauty. Flora, Fauna, and Merryweather appears as recurring character in the American animated television series "Sofia the First", as the headmistresses of Royal Prep. Aurora appeared in the 24th episode of the series, "Holiday in Enchancia". The series features characters from the
Sleeping Beauty transposon system widespread human application of gene therapy in first-world nations as well as countries with developing economies can be envisioned if the costs of the vector system are affordable. Because the SB system is composed solely of DNA, the costs of production and delivery are considerably reduced compared to viral vectors. The first clinical trials using SB transposons in genetically modified T cells will test the efficacy of this form of gene therapy in patients at risk of death from advanced malignancies. Sleeping Beauty transposon system The "Sleeping Beauty" transposon system is a synthetic DNA transposon designed to introduce precisely defined