Manganese 50 µg Mn/L. A protein called DMT1 is the major transporter in manganese absorption from the intestine, and may be the major transporter of manganese across the blood–brain barrier. DMT1 also transports inhaled manganese across the nasal epithelium. The proposed mechanism for manganese toxicity is that dysregulation leads to oxidative stress, mitochondrial dysfunction, glutamate-mediated excitoxicity, and aggregation of proteins. Manganese Manganese is a chemical element with symbol Mn and atomic number 25. It is not found as a free element in nature; it is often found in minerals in combination with iron. Manganese is a metal with important industrial metal
Manganese peroxidase the presence of O, can oxidize lignin or react with water to form HO. The Mn3+ ion itself can degrade lignin by catalyzing alkyl-aryl cleavages and α-carbon oxidation in phenols. MnP activity is controlled via transcriptional regulation. MnP is up-regulated by increases in extracellular Mn(II) and HO concentrations. It has been found that increased O concentration and heat stress also activate MnP. Manganese peroxidase In enzymology, a manganese peroxidase () is an enzyme that catalyzes the chemical reaction The 3 substrates of this enzyme are Mn(II), H, and HO, whereas its two products are Mn(III) and HO. This enzyme belongs