Sciatic nerve behind (superficial to) the adductor magnus muscle, and is itself in front of (deep to) one head of the biceps femoris muscle. At the popliteal fossa, the nerve divides into its two branches: The sciatic nerve is the largest nerve in the human body. The sciatic nerve supplies sensation to the skin of the foot, as well as the entire lower leg (except for its inner side). Sensation to skin to the sole of the foot is provided by the tibial nerve, and the lower leg and upper surface of the foot via the common fibular nerve. The sciatic nerve
Nerve connect to the central nervous system: Specific terms are used to describe nerves and their actions. A nerve that supplies information to the brain from an area of the body, or controls an action of the body is said to "innervate" that section of the body or organ. Other terms relate to whether the nerve affects the same side ("ipsilateral") or opposite side ("contralateral") of the body, to the part of the brain that supplies it. Nerve growth normally ends in adolescence, but can be re-stimulated with a molecular mechanism known as "Notch signaling". If the axons of a neuron