Sleeping Beauty (franchise) such as the "Sleeping Beauty" characters. Characters from "Sleeping Beauty" also make minor appearances in the direct-to-video films based in the show, "" and "Mickey's House of Villains". Fantasy television series "Once Upon a Time" regularly include live-action interpretations of characters including Maleficent, Aurora, Phillip, King Stefan, and Aurora's mother is mentioned as Briar Rose, the "original" Sleeping Beauty. Flora, Fauna, and Merryweather appears as recurring character in the American animated television series "Sofia the First", as the headmistresses of Royal Prep. Aurora appeared in the 24th episode of the series, "Holiday in Enchancia". The series features characters from the
Sleeping Beauty transposon system Sleeping Beauty transposon system The "Sleeping Beauty" transposon system is a synthetic DNA transposon designed to introduce precisely defined DNA sequences into the chromosomes of vertebrate animals for the purposes of introducing new traits and to discover new genes and their functions. It is a Tc1/mariner-type system, with the transposase resurrected from multiple inactive fish sequences. The "Sleeping Beauty" transposon system is composed of a "Sleeping Beauty" (SB) transposase and a transposon that was designed in 1997 to insert specific sequences of DNA into genomes of vertebrate animals. DNA transposons translocate from one DNA site to another in a simple,