Hydrochloric acid enzyme pepsin by self-cleavage. After leaving the stomach, the hydrochloric acid of the chyme is neutralized in the duodenum by sodium bicarbonate. The stomach itself is protected from the strong acid by the secretion of a thick mucus layer, and by secretin induced buffering with sodium bicarbonate. Heartburn or peptic ulcers can develop when these mechanisms fail. Drugs of the antihistaminic and proton pump inhibitor classes can inhibit the production of acid in the stomach, and antacids are used to neutralize excessive existing acid. Concentrated hydrochloric acid (fuming hydrochloric acid) forms acidic mists. Both the mist and the solution have
What Kate Does reviews"; however, this was down significantly from the previous episode's 89 and Bonnie Covel of About.com noted that " 'What Kate Does' brought us a bit of negativity. In general, fans just didn't like the episode". "What Kate Does" was largely considered to be a step down from the season premiere in pacing, revelations and writing; Mike Hale of "The New York Times" described the episode as "contemplative", "anticlimactic" and "subdued" and the flash sideways as "kind of boring and seemingly pointless." Chris Carabott of IGN, who gave the episode a score of 7.3 summed up that " 'What Kate