Ruta graveolens the isolation of the furanocoumarin chalepensin. The essential oil of "R. graveolens" contains two main constituents, undecan-2-one (46.8%) and nonan-2-one (18.8%). The bitter taste of its leaves led to rue being associated with the (etymologically unrelated) verb "rue" "to regret". Rue is well known for its symbolic meaning of regret and it has sometimes been called "herb-of-grace" in literary works. It is one of the flowers distributed by the mad Ophelia in William Shakespeare's "Hamlet" (IV.5): It was planted by the gardener in "Richard II" to mark the spot where the Queen wept upon hearing news of Richard's capture (III.4.104–105):
Hamlet adept at matching rhetorical devices to characters and the plot. Linguist George T. Wright suggests that hendiadys had been used deliberately to heighten the play's sense of duality and dislocation. Pauline Kiernan argues that Shakespeare changed English drama forever in "Hamlet" because he "showed how a character's language can often be saying several things at once, and contradictory meanings at that, to reflect fragmented thoughts and disturbed feelings". She gives the example of Hamlet's advice to Ophelia, "get thee to a nunnery", which is simultaneously a reference to a place of chastity and a slang term for a brothel, reflecting