Magnesium in biology be used as adjuvant therapy in patients on optimal treatment for severe congestive heart failure, increasing survival rate and improving clinical symptoms and patient's quality of life. Magnesium can affect muscle relaxation through direct action on cell membranes. Mg ions close certain types of calcium channels, which conduct positively charged calcium ions into neurons. With an excess of magnesium, more channels will be blocked and nerve cells activity will decrease. Intravenous magnesium sulphate is used in treating pre-eclampsia. For other than pregnancy-related hypertension, a meta-analysis of 22 clinical trials with dose ranges of 120 to 973 mg/day and a mean
Magnesium alloy the elongation of the alloys but results in decreased strength. Magnesium alloys harden rapidly with any type of cold work, and therefore cannot be extensively cold formed without repeated annealing. Sharp bending, spinning, or drawing must be done at about , although gentle bending around large radii can be done cold. Slow forming gives better results than rapid shaping. Press forging is preferred to hammer forging, because the press allows greater time for metal flow. The plastic forging range is . Metal worked outside this range is easily broken. Magnesium alloys, especially precipitation hardened alloys, are used in casting. Sand,