Tilling (Sussex) story, "Diplomatic Incident", for the former Tilling Society in 1998 and another called "Great Minds" for the Friends of Tilling in 2006. The Friends of Tilling organise an annual gathering in Rye each September for devotees of Mapp & Lucia and E F Benson's other comic novels. Two other Tilling books, "Major Benjy" and "Au Reservoir", were written by Guy Fraser-Sampson and published by Troubador. In 2014 the BBC made a new three-part series adapted by Steve Pemberton (who also played Georgie Pillson) from the original "Mapp and Lucia" novel. Lamb House was the model for "Mallards", the home initially
TILLING (molecular biology) relies on the formation of DNA heteroduplexes that are formed when multiple alleles are amplified by PCR and are then heated and slowly cooled. A “bubble” forms at the mismatch of the two DNA strands, which is then cleaved by a single stranded nucleases. The products are then separated by size on several different platforms (see below). Mismatches may be due to induced mutation, heterozygosity within an individual, or natural variation between individuals. EcoTILLING is a method that uses TILLING techniques to look for natural mutations in individuals, usually for population genetics analysis. DEcoTILLING is a modification of TILLING and