Ruta graveolens the isolation of the furanocoumarin chalepensin. The essential oil of "R. graveolens" contains two main constituents, undecan-2-one (46.8%) and nonan-2-one (18.8%). The bitter taste of its leaves led to rue being associated with the (etymologically unrelated) verb "rue" "to regret". Rue is well known for its symbolic meaning of regret and it has sometimes been called "herb-of-grace" in literary works. It is one of the flowers distributed by the mad Ophelia in William Shakespeare's "Hamlet" (IV.5): It was planted by the gardener in "Richard II" to mark the spot where the Queen wept upon hearing news of Richard's capture (III.4.104–105):
Hamlet (video game) Denis Galanin, also known as mif2000. Hamlet (video game) Hamlet or the Last Game without MMORPG Features, Shaders and Product Placement (or Hamlet on Android and Hamlet! on iOS) is an indie adventure game based on William Shakespeare's "Hamlet". It was developed and published by indie game developer Denis Galanin. A scientist travels back in time and gets mixed up with characters from William Shakespeare's play, Hamlet Guide the man from the future as he embarks on a mission to save Hamlet's girlfriend, Ophelia, from the clutches of the evil Claudius. Solve a variety of point-and-click puzzles and advance from