Magnesium aspartate salts of magnesium have the greatest water solubility and demonstrate a greater oral absorption and bioavailability compared to less soluble magnesium preparations such as magnesium oxide, magnesium hydroxide, magnesium carbonate and magnesium sulphate. Magnesium-L-aspartate 1230 mg (magnesium 122 mg) up to 3 times/day Dosage adjustment in renal impairment: Patients with severe renal failure should not receive magnesium due to toxicity from accumulation. Magnesium supplements and other magnesium containing products, such as antacids, can bind with prescription medicines, reducing their effectiveness. Aspartate and glutamate are excitatory neurotransmitters. At high doses (consumed either independently or in excess of other protein–containing foods), can
Magnesium ions interact with polyphosphate compounds such as ATP, DNA, and RNA. Hundreds of enzymes require magnesium ions to function. Magnesium compounds are used medicinally as common laxatives, antacids (e.g., milk of magnesia), and to stabilize abnormal nerve excitation or blood vessel spasm in such conditions as eclampsia. Elemental magnesium is a gray-white lightweight metal, two-thirds the density of aluminium. It tarnishes slightly when exposed to air, although, unlike the heavier alkaline earth metals, an oxygen-free environment is unnecessary for storage because magnesium is protected by a thin layer of oxide that is fairly impermeable and difficult to remove. Magnesium has