Spinal nerve nerve roots result in typical patterns of neurologic defects (muscle weakness, abnormal sensation, changes in reflexes) that allow localization of the responsible lesion. There are several procedures used in sacral nerve stimulation for the treatment of various related disorders. Sciatica is generally caused by the compression of lumbar nerves L4, or L5 or sacral nerves S1, S2, or S3, or by compression of the sciatic nerve itself. Spinal nerve A spinal nerve is a mixed nerve, which carries motor, sensory, and autonomic signals between the spinal cord and the body. In the human body there are 31 pairs of spinal
Nerve allograft to bridge the gap is nerve allotransplantation. Nerve allografts are prepared from donated human nerve tissue. An allograft contains many of the beneficial characteristics of nerve autograft, such as three-dimensional microstructural scaffolding and protein components inherent to nerve tissue. One of the adverse effects of nerve allotransplantation is the immunogenic response. Tissue from another human being is used to restore the defect, which can induce an immunogenic response. An immune response against an allograft or xenograft is called Transplant rejection. To prevent this rejection, new immunosuppressive techniques are performed on the graft, before it is transplanted into the receiver. The