Manganese produce a parkinsonism-like illness characterized by movement abnormalities. This condition is not responsive to typical therapies used in the treatment of PD, suggesting an alternative pathway than the typical dopaminergic loss within the substantia nigra. Manganese may accumulate in the basal ganglia, leading to the abnormal movements. A mutation of the SLC30A10 gene, a manganese efflux transporter necessary for decreasing intracellular Mn, has been linked with the development of this Parkinsonism-like disease. The Lewy bodies typical to PD are not seen in Mn-induced parkinsonism. Animal experiments have given the opportunity to examine the consequences of manganese overexposure under controlled conditions.
Symbol (chemistry) (namely those in the actinium decay family, the radium decay family, and the thorium decay family) bear placeholder names using the early naming system devised by Ernest Rutherford. General: From organic chemistry: Exotic atoms: Symbol (chemistry) In relation to the chemical elements, a symbol is a code for a chemical element. Many functional groups have their own chemical symbol, e.g. Ph for the phenyl group, and Me for the methyl group. Chemical symbols for elements normally consist of one or two letters from the Latin alphabet, but can contain three when the element has a systematic temporary name (as of