Gastric acid network (called canaliculi) from which the hydrochloric acid is secreted into the lumen of the stomach. The pH of gastric acid is 1.5 to 3.5 in the human stomach lumen, the acidity being maintained by the proton pump H/K ATPase. The parietal cell releases bicarbonate into the bloodstream in the process, which causes a temporary rise of pH in the blood, known as an alkaline tide. The highly acidic environment in the stomach lumen causes proteins from food to lose their characteristic folded structure (or denature). This exposes the protein's peptide bonds. The gastric chief cells of the stomach secrete
Break Up, Break Down the Reigning Sound; Greg Cartwright on lead vocals and guitar; Alex Greene on organ, piano, guitar, and backing vocals; Jeremy Scott on bass and backing vocals; and Greg Roberson on drums. Break Up, Break Down Break Up, Break Down is the first studio album by the Reigning Sound. It was released on May 15, 2001 by Sympathy for the Record Industry. The album was the band's second release, following their debut 7" single "Two Sides to Every Man," by three months. Its country-folk melodies stood in stark contrast to some of frontman Greg Cartwright's earlier work with bands such as