Gastric acid network (called canaliculi) from which the hydrochloric acid is secreted into the lumen of the stomach. The pH of gastric acid is 1.5 to 3.5 in the human stomach lumen, the acidity being maintained by the proton pump H/K ATPase. The parietal cell releases bicarbonate into the bloodstream in the process, which causes a temporary rise of pH in the blood, known as an alkaline tide. The highly acidic environment in the stomach lumen causes proteins from food to lose their characteristic folded structure (or denature). This exposes the protein's peptide bonds. The gastric chief cells of the stomach secrete
What It Comes Down To What It Comes Down To "What It Comes Down To" is a song by The Isley Brothers, who released it in late 1973 as a follow-up to the group's crossover pop hit, "That Lady, Pt. 1 & 2". Both songs were featured on the group's Epic debut, "3 + 3". It features a synthesizer keyboard solo from Chris Jasper, Ernie Isley on guitar and Ronald Isley on lead vocals. The b-side of the song was the ballad "The Highways Of My Life". The song peaked at number 55 on the "Billboard" Hot 100 and was a top five hit on