Magnesium aspartate salts of magnesium have the greatest water solubility and demonstrate a greater oral absorption and bioavailability compared to less soluble magnesium preparations such as magnesium oxide, magnesium hydroxide, magnesium carbonate and magnesium sulphate. Magnesium-L-aspartate 1230 mg (magnesium 122 mg) up to 3 times/day Dosage adjustment in renal impairment: Patients with severe renal failure should not receive magnesium due to toxicity from accumulation. Magnesium supplements and other magnesium containing products, such as antacids, can bind with prescription medicines, reducing their effectiveness. Aspartate and glutamate are excitatory neurotransmitters. At high doses (consumed either independently or in excess of other protein–containing foods), can
Magnesium than recommended in the Dietary Reference Intake. Other causes are increased renal or gastrointestinal loss, an increased intracellular shift, and proton-pump inhibitor antacid therapy. Most are asymptomatic, but symptoms referable to neuromuscular, cardiovascular, and metabolic dysfunction may occur. Alcoholism is often associated with magnesium deficiency. Chronically low serum magnesium levels are associated with metabolic syndrome, diabetes mellitus type 2, fasciculation, and hypertension. Sorted by type of magnesium salt, other therapeutic applications include: Overdose from dietary sources alone is unlikely because excess magnesium in the blood is promptly filtered by the kidneys, and overdose is more likely in the presence of