Magnesium in biology be used as adjuvant therapy in patients on optimal treatment for severe congestive heart failure, increasing survival rate and improving clinical symptoms and patient's quality of life. Magnesium can affect muscle relaxation through direct action on cell membranes. Mg ions close certain types of calcium channels, which conduct positively charged calcium ions into neurons. With an excess of magnesium, more channels will be blocked and nerve cells activity will decrease. Intravenous magnesium sulphate is used in treating pre-eclampsia. For other than pregnancy-related hypertension, a meta-analysis of 22 clinical trials with dose ranges of 120 to 973 mg/day and a mean
Magnesium malate characteristic of having two elemental magnesium molecules, whereas magnesium malate has a single elemental magnesium molecule. Magnesium malate Magnesium malate, the magnesium salt of malic acid, is a mineral supplement often used for nutritional concerns. It is represented by the chemical formula C4H4MgO5 and has a molecular weight of 156.376 g/mol. Magnesium malate is discussed as being a more bioavailable form of magnesium, along with other forms such as citrate and glycinate. Dimagnesium malate is another common form of this compound seen in the dietary supplement market, produced by such dimetalhydroxy malate-yielding processes as the one described by a 1997