Magnesium in biology be used as adjuvant therapy in patients on optimal treatment for severe congestive heart failure, increasing survival rate and improving clinical symptoms and patient's quality of life. Magnesium can affect muscle relaxation through direct action on cell membranes. Mg ions close certain types of calcium channels, which conduct positively charged calcium ions into neurons. With an excess of magnesium, more channels will be blocked and nerve cells activity will decrease. Intravenous magnesium sulphate is used in treating pre-eclampsia. For other than pregnancy-related hypertension, a meta-analysis of 22 clinical trials with dose ranges of 120 to 973 mg/day and a mean
Magnesium oxide Magnesium oxide Magnesium oxide (MgO), or magnesia, is a white hygroscopic solid mineral that occurs naturally as periclase and is a source of magnesium (see also oxide). It has an empirical formula of and consists of a lattice of Mg ions and O ions held together by ionic bonding. Magnesium hydroxide forms in the presence of water (MgO + HO → Mg(OH)), but it can be reversed by heating it to separate moisture. Magnesium oxide was historically known as magnesia alba (literally, the white mineral from magnesia – other sources give magnesia alba as MgCO), to differentiate it from "magnesia