Burrill Bernard Crohn published paper was "Regional Ileitis: A Pathologic and Clinical Entity". Crohn's work helped correct the thinking that the ailment was actually a form of tuberculosis rather than an inflammatory disease of the gastrointestinal tract. Crohn's work built on the work of Dr. Kennedy Dalziel of Glasgow into regional enteritis twenty years earlier. Crohn always preferred the medically descriptive terms "regional ileitis" and "regional enteritis" to "Crohn's disease", but he was not able to prevent the appropriation of his name for the disease. Some of Crohn's initial research into the causes of the Crohn's disease was centered around his personal conviction
Adult polyglucosan body disease People with adult polyglucosan body disease typically first experience signs and symptoms related to the condition between ages 30 and 60. APBD is an autosomal recessive disorder that is caused when a person inherits genes from both parents containing one or more loss-of-function mutations in the gene "GBE1" which encodes for glycogen branching enzyme, also called 1,4-alpha-glucan-branching enzyme. The "GBE1" gene provides instructions for making the glycogen branching enzyme. This enzyme is involved in the production of a complex sugar called glycogen, which is a major source of stored energy in the body. Most "GBE1" gene mutations result in a