Allergic response itchiness, swelling, running nose, watery eyes, coughing, wheezing, trouble breathing, hives, rashes, mucus production, or a more severe reaction anaphylaxis. Allergic responses and the severity vary from person to person. Many substances can trigger an allergic reaction. Common triggers of a reaction include foods, likes nuts, eggs, milk, gluten, fruit and vegetables; insect bites from bees or wasps (often a severe response occurs); environmental factors such as pollen, dust, mold, plants like grass or trees, animal dander; medications or chemicals. Some people experience an allergic response to cold or hot temperatures outside, jewelry or sunlight. There are daily treatments to
Allergic inflammation hours and is mediated by mast cells) should not be confused with delayed hypersensitivity Type IV allergic reaction (which takes 48–72 hours to develop and is mediated by T cells). The products of the early phase reaction include chemokines and molecules that act on endothelial cells and cause them to express Intercellular adhesion molecule (such as vascular cell adhesion molecule and selectins), which together result in the recruitment and activation of leukocytes from the blood into the site of the allergic reaction. Typically, the infiltrating cells observed in allergic reactions contain a high proportion of lymphocytes, and especially, of eosinophils.