Despicable Me 2 became the second-highest-grossing animated film of 2013 and the third highest-grossing film of 2013. It is also the most profitable film in the 101-year history of Universal Studios. A spinoff/prequel film, "Minions", focusing on the little yellow henchmen before they met Gru, was released on July 10, 2015. A sequel, "Despicable Me 3", was released on June 30, 2017. A mysterious vehicle using a giant magnet steals a highly potent mutagen known as PX-41 from a secret laboratory in the Arctic Circle. The Anti-Villain League (AVL), led by Silas Ramsbottom, tries to recruit former super-villain Gru to track down the
Isla Fisher worldwide. Fisher also voiced a professor in a city of microscopic creatures in the computer-animated comedy hit "Horton Hears a Who!" (2008), featuring Jim Carrey, Steve Carell, Will Arnett, among others. Fisher obtained her first leading film role in the comedy "Confessions of a Shopaholic" (2009), where she played a college graduate who works as a financial journalist in New York City to support her shopping addiction. She felt "apprehensive" as she took on her first star vehicle, stating: "I was gobsmacked that anyone would give me my own movie. I am eternally bewildered. Every time I see [producer] Jerry