Coeliac disease Coeliac disease Coeliac disease or celiac disease is a long-term autoimmune disorder that primarily affects the small intestine. Classic symptoms include gastrointestinal problems such as chronic diarrhoea, abdominal distention, malabsorption, loss of appetite and among children failure to grow normally. This often begins between six months and two years of age. Non-classic symptoms are more common, especially in people older than two years. There may be mild or absent gastrointestinal symptoms, a wide number of symptoms involving any part of the body or no obvious symptoms. Coeliac disease was first described in childhood; however, it may develop at any age.
Dieterich's disease or therapy. The cause of Dieterich’s disease is still not fully understood. The disease can afflict patients of any age, but typically affects patients in their 30's. Though rare, it can also occur in children. Statistics show that generally more men are affected by Dieterich's than women in an estimated ratio of 3:2. The third (middle finger) metacarpal head has been reported to be the most common site of necrosis. Though osteonecrosis is a fairly common condition, many cases of avascular necrosis of the metacarpal hand go without being diagnosed. This is because presentation of symptoms is variable depending on