Pterois Rarely, such stings can cause temporary paralysis of the limbs, heart failure, and even death. Fatalities are common in very young children, the elderly, those with a weak immune system, or those who are allergic to their venom. Their venom is rarely fatal to healthy adults, but some species have enough venom to produce extreme discomfort for a period of several days. However, "Pterois" venom is a danger to allergic victims as they may experience anaphylaxis, a serious and often life-threatening condition that requires immediate emergency medical treatment. Severe allergic reactions to "Pterois" venom include chest pain, severe breathing difficulties,
Allergic inflammation hours and is mediated by mast cells) should not be confused with delayed hypersensitivity Type IV allergic reaction (which takes 48–72 hours to develop and is mediated by T cells). The products of the early phase reaction include chemokines and molecules that act on endothelial cells and cause them to express Intercellular adhesion molecule (such as vascular cell adhesion molecule and selectins), which together result in the recruitment and activation of leukocytes from the blood into the site of the allergic reaction. Typically, the infiltrating cells observed in allergic reactions contain a high proportion of lymphocytes, and especially, of eosinophils.