Omalizumab and the World Health Organization. It is also used to treat people 12 years and above with chronic spontaneous urticaria (also called chronic idiopathic urticaria), which cannot be treated with elevated doses of H1-antihistamines. The main adverse effect is anaphylaxis (a life-threatening systemic allergic reaction), with a rate of occurrence of 1 to 2 patients per 1,000. Like other protein and antibody drugs, omalizumab also causes anaphylaxis, although at a relatively low frequency among antibody drugs. The allergic reaction is probably not due to the binding characteristics of the antibody drug, but to the protein nature of the antibody. The
What Is Life early June. The same core of musicians – Bobby Whitlock, Carl Radle, Jim Gordon, Bobby Keys and Jim Price – would similarly elevate other "All Things Must Pass" tracks such as "Awaiting on You All", "Art of Dying" and "Hear Me Lord". The recording is defined by Harrison's descending, fuzztone guitar riff, which also serves as the motif for the chorus.<ref name="Unterberger/AM">Richie Unterberger, "George Harrison 'What Is Life'", AllMusic (retrieved 22 February 2012).</ref> The track opens with this riff, which is then joined by Radle's bass and "churning" rhythm guitar from Clapton, before Gordon's drums bring the full band in.