Platonic solid to that of a sphere of the same size (i.e. either the same surface area or the same volume.) The dodecahedron, on the other hand, has the smallest angular defect, the largest vertex solid angle, and it fills out its circumscribed sphere the most. Every polyhedron has a dual (or "polar") polyhedron with faces and vertices interchanged. The dual of every Platonic solid is another Platonic solid, so that we can arrange the five solids into dual pairs. If a polyhedron has Schläfli symbol {"p", "q"}, then its dual has the symbol {"q", "p"}. Indeed, every combinatorial property of one
Accessible surface area is a numerical method that draws a mesh of points equidistant from each atom of the molecule and uses the number of these points that are solvent accessible to determine the surface area. The points are drawn at a water molecule's estimated radius beyond the van der Waals radius, which is effectively similar to ‘rolling a ball’ along the surface. All points are checked against the surface of neighboring atoms to determine whether they are buried or accessible. The number of points accessible is multiplied by the portion of surface area each point represents to calculate the ASA. The choice