Cartilage as the cricoid cartilage and carina. Cartilage is composed of specialized cells called chondrocytes that produce a large amount of collagenous extracellular matrix, abundant ground substance that is rich in proteoglycan and elastin fibers. Cartilage is classified in three types, "elastic cartilage", "hyaline cartilage" and "fibrocartilage", which differ in relative amounts of collagen and proteoglycan. Cartilage does not contain blood vessels (it is avascular) or nerves (it is aneural). Nutrition is supplied to the chondrocytes by diffusion. The compression of the articular cartilage or flexion of the elastic cartilage generates fluid flow, which assists diffusion of nutrients to the chondrocytes.
Tissues and Issues Tissues and Issues Tissues and Issues is the fifth studio album by the Welsh singer Charlotte Church released by Sony BMG UK in the United Kingdom on 11 July 2005 (see 2005 in music). Church states that she titled the album "Tissues and Issues" because "it epitomises teenage problems, which everybody goes through." The album debuted on the UK Albums Chart at number five and was accredited platinum by BPI for sales over 300,000. The album yielded Church four successful top twenty singles; "Crazy Chick", "Call My Name", "Even God" and "Moodswings (to Come at Me like That)". The album