Spanish East Indies chief consort, and his subjects. Seeking to develop trade between the East Indies and the Americas across the Pacific Ocean, Antonio de Mendoza encouraged the exploration of these Asian territories and commissioned the expedition of Ruy López de Villalobos to the Philippines in 1542–1543. Miguel López de Legazpi set out from Mexico, and established the first Spanish settlement in the Philippines in 1565, which became the town of San Miguel in present-day Cebu. That same year, another member of the expedition, Andrés de Urdaneta discovered a maritime route from the Philippines to Mexico, across the Pacific, leading to the important
Spanish East Indies he should provide the most convenient to the service of God and ours and the peace and tranquility of said Province and Republic". The Spanish East Indies came to be defined as: The Spanish used several names that are not currently used. Gran Moluca (Great Molluccas) for the island of Mindanao and Nueva Castilla (New Castile) for Luzon. Because Spanish interest in the region was primarily focused on its use as a base for trade with East Asia, direct Spanish control over the area expanded slowly. The Batanes Islands were conquered in the 18th century by José Basco. The highlands