Insect sting allergy potentially something very serious and can lead to anaphylaxis, which is potentially life-threatening. The majority of individuals who receive a sting from an insect experience local reactions. It is estimated that 5-10% of individuals will experience a generalized systemic reaction that can involve symptoms ranging from hives to wheezing and even anaphylaxis. In the United States approximately 40 people die each year from anaphylaxis due to stinging insect allergy. Potentially life-threatening reactions occur in 3% of adults and 0.4–0.8% of children. A 2012 meta-analysis found that venom immunotherapy is an effective prophylactic treatment against insect bite and sting allergic reactions,
What Is Life "Close to the Edge", "Mojo", December 2003, p. 82.</ref> It was while driving up to a Preston session in London from his home in Esher, Surrey, that Harrison came up with the song "What Is Life". In his autobiography, "I, Me, Mine", Harrison describes it as having been written "very quickly" and recalls that he thought it would be a perfect, "catchy pop song" for Preston to record. His lyrics, while simple, were similarly uplifting and universal: These lyrics have caused some debate among biographers and music critics, as to whether "What Is Life" should be viewed as a straightforward