Amblyomma americanum mammalian meat and meat products. The allergy manifests as anaphylaxis — a life-threatening allergic reaction characterized by constriction of airways and a drop in blood pressure. This response is triggered by an IgE antibody to the mammalian oligosaccharide galactose-alpha-1,3-galactose (alpha-gal). As well as occurring in non-primate mammals, alpha-gal is also found in cat dander and in the drug cetuximab. Allergic reactions to alpha-gal usually occur 3–6 hours after consuming red meat, unlike allergic reactions to other foods, whose onset following consumption is more or less immediate, making it more difficult to identify what caused the reaction. Skin tests with standard
Allergic transfusion reaction from a donor who has allergies, followed by antigen exposure. An allergic transfusion reaction is a type of transfusion reaction that is defined according to the Center for Disease Control (CDC) as: An allergic transfusion reaction is diagnosed if two or more of the following occur within 4 hours of cessation of transfusion: A probable diagnosis results if any one of the following occurring within 4 hours of cessation of transfusion: Treatment of an allergic transfusion reaction is to immediate stop the transfusion. If the only symptoms are mild (i.e., hives and itching), the patient may be treated with an