Inflammatory bowel disease inflammatory changes. Crohn's can affect any part of the gastrointestinal tract, from mouth to anus ("skip lesions"), although a majority of the cases start in the terminal ileum. Ulcerative colitis, in contrast, is restricted to the colon and the rectum. Microscopically, ulcerative colitis is restricted to the mucosa (epithelial lining of the gut), while Crohn's disease affects the full thickness of the bowel wall ("transmural lesions"). Lastly, Crohn's disease and ulcerative colitis present with extra-intestinal manifestations (such as liver problems, arthritis, skin manifestations and eye problems) in different proportions. In 10–15% of cases, a definitive diagnosis neither of Crohn's disease
The Gifts of the Body the patients and the caregiver. The book contains ten short stories, the titles of each being associated with "gifts" which are various functions of the body, both physical and emotional: sweat, wholeness, tears, skin, hunger, mobility, death, speech, sight, hope, and mourning. The caregiver experiences each "gift", as he/she deals with patients who have AIDS, showing the different shared relationships in each case. Each patient is a distinct case, differing in terms of age, financial situation, attitude toward the illness etc., showing the reader that this disease affects all types of people. The book is written in the "no-frills style"