Omalizumab and the World Health Organization. It is also used to treat people 12 years and above with chronic spontaneous urticaria (also called chronic idiopathic urticaria), which cannot be treated with elevated doses of H1-antihistamines. The main adverse effect is anaphylaxis (a life-threatening systemic allergic reaction), with a rate of occurrence of 1 to 2 patients per 1,000. Like other protein and antibody drugs, omalizumab also causes anaphylaxis, although at a relatively low frequency among antibody drugs. The allergic reaction is probably not due to the binding characteristics of the antibody drug, but to the protein nature of the antibody. The
Finafloxacin disorders, including rhinitis and nasopharyngitis, have also been associated with the use of finafloxacin. People that are allergic to other quinolones may be allergic to finafloxacin as well, and use may result in an allergic reaction in that population. Adverse effects consistent with an allergic reaction to finafloxacin may include swelling of the lips, tongue, or throat, difficulty swallowing, and shortness of breath. It is not thought that an overdose of the "otic suspension" is likely to cause severe or life-threatening symptoms. Owing to the local effect of administering finafloxacin into the ears, it is unlikely that it will affect