Roca dels Bous (archaeological site) interesting archaeological site indeed. Furthermore, it is to be noted that the samples used for the 14C AMS dating were obtained from deep strata at the site. The oldest Neanderthal sites known in the nearby areas date back to around 40,000 BP. The first settlements attributed to “anatomically modern” Homo sapiens sapiens in Northern Spain are dated around 39,000-38,000 BP. All this would suggest that Neanderthals could have persisted in this particular area longer than previously believed, preceding the arrival of the first Homo sapiens to the area. Research work began in 1988. This wide period of time has contributed
Kinetic isotope effect reach the transition state (or, in rare cases, the dissociation limit), and consequently, a slower reaction rate. The study of kinetic isotope effects can help the elucidation of the reaction mechanism of certain chemical reactions and is occasionally exploited in drug development to improve unfavorable pharmacokinetics by protecting metabolically-vulnerable C-H bonds. The kinetic isotope effect is considered to be one of the most essential and sensitive tools for the study of reaction mechanisms, the knowledge of which allows the improvement of the desirable qualities of the corresponding reactions. For example, kinetic isotope effects can be used to reveal whether a