Xiyanping allergic reaction, most commonly erythema and pruritus around the injection site, but more rarely anaphylactic reactions may occur, which can be life-threatening. Also, andrographolide and related derivatives are known to be abortifacient, making xiyanping unsuitable for use in pregnant women. Xiyanping Xiyanping (喜炎平) is an anti-inflammatory and antiviral preparation developed and licensed for use in China. It is a semi-synthetic injectable product derived from the active component of the plant "Andrographis paniculata" (Chuan Xin Lian, 穿心蓮), which is used in Traditional Chinese medicine. Xiyanping is primarily composed of 9-dehydro-17-hydro-andrographolide and sodium 9-dehydro-17-hydro-andrographolide-19-yl sulfate. It is used mainly in the treatment
Allergic inflammation hours and is mediated by mast cells) should not be confused with delayed hypersensitivity Type IV allergic reaction (which takes 48–72 hours to develop and is mediated by T cells). The products of the early phase reaction include chemokines and molecules that act on endothelial cells and cause them to express Intercellular adhesion molecule (such as vascular cell adhesion molecule and selectins), which together result in the recruitment and activation of leukocytes from the blood into the site of the allergic reaction. Typically, the infiltrating cells observed in allergic reactions contain a high proportion of lymphocytes, and especially, of eosinophils.