Earl of Salisbury later by Richard Neville "the Kingmaker", upon whose death the title went into abeyance because multiple individuals were entitled to inherit it. Then, in 1472, it was granted to George, Duke of Clarence, who was married to Warwick's eldest daughter. When the Duke of Clarence was executed in 1478 for treason (supposedly by being drowned in a vat of Malmsey wine), the title was forfeit. It was then granted to Edward of Middleham (who was his nephew via the Duke's brother Richard), who died in 1484 at the age of 11. It was restored to two of George of Clarence's
Hugh Butt Hugh Butt Hugh Roland Butt (January 8, 1910 – August 16, 2008) was an American physician who developed methods to treat hemorrhaging patients with vitamin K. Butt was born in Belhaven, North Carolina. He earned his M.D. from the University of Virginia in 1933 and a master's degree in medicine from the University of Minnesota in 1937. Butt was a resident at the Mayo Clinic when he made his most notable finding that Vitamin K stopped bleeding in patients with jaundice, previously a fatal condition. He later worked with dicumarol isolated by Paul Link, and conducted the first human studies