Chimera (mythology) (that does not occur with depictions of male lions). Sighting the Chimera was an omen of storms, shipwrecks, and natural disasters (particularly volcanoes). While there are different genealogies, in one version the Chimera mated with her brother Orthrus and was the mother of the Sphinx and the Nemean lion (others have Orthrus and their mother, Echidna, mating; most attribute all to Typhon and Echidna). The Chimera finally was defeated by Bellerophon with the help of Pegasus, at the command of King Iobates of Lycia, after terrorizing Lycia and nearby lands. Since Pegasus could fly, Bellerophon shot the Chimera from the
Zinc finger chimera adjacent to it, a situation known as target-site overlap. ZFP-TFs, consisting of activators and repressors are transcription factors composed of a zinc finger protein domain and any of a variety of transcription-factor effector-domains which exert their modulatory effect around any sequence to which the ZFP domain binds. Zinc finger nucleases include a nuclease domain such as FokI, capable of introducing double-stranded breaks at the locus of any sequence to which the zinc finger protein domain binds. Zinc finger chimera Zinc finger protein chimera are chimeric proteins composed of a DNA-binding zinc finger protein domain and another domain through which the