Omalizumab and the World Health Organization. It is also used to treat people 12 years and above with chronic spontaneous urticaria (also called chronic idiopathic urticaria), which cannot be treated with elevated doses of H1-antihistamines. The main adverse effect is anaphylaxis (a life-threatening systemic allergic reaction), with a rate of occurrence of 1 to 2 patients per 1,000. Like other protein and antibody drugs, omalizumab also causes anaphylaxis, although at a relatively low frequency among antibody drugs. The allergic reaction is probably not due to the binding characteristics of the antibody drug, but to the protein nature of the antibody. The
What Is Life what he needs from his old band – that insinuating hook sense – and uses it to frame an utterly comfortable metaphysical discourse". Alan Clayson describes "What Is Life" as a seemingly "lovey-dovey pop song" that "craftily renewed the simplistic tonic-to-dominant riff cliché", while Simon Leng credits Harrison's "innate ability to write very fine pop-rock songs" and deems the result "as innovative an exercise in rock-soul as The Temptations' 'Cloud Nine'". Among Harrison biographers, only Ian Inglis is less than enthusiastic, acknowledging that Barham's orchestration and the other musicians give the track "undoubted excitement and energy", but lamenting that the