Burrill Bernard Crohn in New Milford, Connecticut. The Burrill B. Crohn Research Foundation was established at Mount Sinai in 1983 with initial funding from Rose Crohn and later his daughter, Ruth Crohn Dickler. Burrill Bernard Crohn Burrill Bernard Crohn (June 13, 1884 – July 29, 1983) was an American gastroenterologist and made the first major advance to identify the disease that now bears his name. Although the description of Crohn's disease is by far his most famous accomplishment, Crohn had a long career both as a clinician, and as a researcher who contributed to modern understanding of many gastrointestinal conditions. Crohn received his
Adult polyglucosan body disease body disease do not have identified mutations in the "GBE1" gene. In these individuals, the cause of the disease is unknown. Along with evaluation of the symptoms and a neurological examination, a diagnosis can be made based on genetic testing. Whether or not a person is making sufficient amounts of functional glycogen branching enzyme can be determined by taking a skin biopsy and testing for activity of the enzyme. Examination of tissue biopsied from the sural nerve under a microscope can reveal the presence of polyglucosan bodies. There will also be white matter changes visible in a magnetic resonance imaging