Insect sting allergy potentially something very serious and can lead to anaphylaxis, which is potentially life-threatening. The majority of individuals who receive a sting from an insect experience local reactions. It is estimated that 5-10% of individuals will experience a generalized systemic reaction that can involve symptoms ranging from hives to wheezing and even anaphylaxis. In the United States approximately 40 people die each year from anaphylaxis due to stinging insect allergy. Potentially life-threatening reactions occur in 3% of adults and 0.4–0.8% of children. A 2012 meta-analysis found that venom immunotherapy is an effective prophylactic treatment against insect bite and sting allergic reactions,
Dermatographic urticaria rapidly break down under physical pressure, which then causes an allergic-like reaction. Symptoms can be caused or induced by: The underlying cause of dermographism is not known, and it can last for many years without relief. The condition may subside and be effectively cured; however, it is often a lifelong ailment. It is not a life-threatening disease, and it is not contagious. Dermographism may occur in mastocytosis (systemic mast cell proliferation). Dermographism can be treated by substances which prevent histamine from causing the reaction (i.e. an antihistamine). These may need to be given as a combination of H antagonists, or