Spanish East Indies chief consort, and his subjects. Seeking to develop trade between the East Indies and the Americas across the Pacific Ocean, Antonio de Mendoza encouraged the exploration of these Asian territories and commissioned the expedition of Ruy López de Villalobos to the Philippines in 1542–1543. Miguel López de Legazpi set out from Mexico, and established the first Spanish settlement in the Philippines in 1565, which became the town of San Miguel in present-day Cebu. That same year, another member of the expedition, Andrés de Urdaneta discovered a maritime route from the Philippines to Mexico, across the Pacific, leading to the important
Spanish West Indies Antilles. Under intermittent periods of Spanish rule, these islands were administered as part of the Spanish Main (initially Guatemala, later New Granada). Spanish West Indies The Spanish West Indies or the Spanish Antilles (also known as "Las Antillas Occidentales" or simply "Las Antillas Españolas" in Spanish) was the former name of the Spanish colonies in the Caribbean. In terms of governance of the Spanish Empire, The Indies was the designation for all its overseas territories and was overseen by the Council of the Indies, founded in 1524 and based in Spain. When the crown established the Viceroyalty of New Spain