Estelle Reiner Harry Met Sally...", in which director Rob Reiner cast his mother as a customer in a scene with stars Billy Crystal and Meg Ryan at Katz's Delicatessen, in which Ryan fakes what was described as "a very public (and very persuasive) orgasm". Approached by a waitress after Ryan finishes, Reiner deadpans "I’ll have what she’s having". The line was ranked 33rd on the American Film Institute's list of the Top 100 movie quotations, just behind "Casablanca"'s "Round up the usual suspects". Reiner died of natural causes on October 25, 2008 at age 94 in her home in Beverly Hills, California.
Meg Ryan in the pilot of "How I Met Your Dad", a woman-centric variation of the CBS sitcom "How I Met Your Mother". CBS later passed on the project. Ryan's next feature film was the ABC Family film "Fan Girl", an independent comedy about a 15-year-old girl, played by Kiernan Shipka, with a passion for filmmaking sets out to make a movie about her favorite band, All Time Low. It premiered at the Los Angeles Film Festival in June 2015. Also in 2015, Ryan made her directing debut with "Ithaca", a drama film based on the 1943 novel "The Human Comedy" by