Very early onset inflammatory bowel disease hand, other types of primary immunodeficiency can often manifest with IBD-like symptoms, too. These include the IPEX syndrome, Wiskott-Aldrich syndrome, XIAP syndrome or chronic granulomatous disease. Inflammatory bowel diseases (IBDs), such as Crohn Disease (CD) or Ulcerative Colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract. Up-to-date findings show that the pathogenesis is influenced by both environmental and genetic factors. A considerable number of monogenic disorders can be found especially among patients with VEOIBD. Causal mutations can be found in genes involved in epithelial barrier formation (COL7A1, FERMT1), innate (CYBB, G6PC3), as well as the specific immune response and
The Gifts of the Body the patients and the caregiver. The book contains ten short stories, the titles of each being associated with "gifts" which are various functions of the body, both physical and emotional: sweat, wholeness, tears, skin, hunger, mobility, death, speech, sight, hope, and mourning. The caregiver experiences each "gift", as he/she deals with patients who have AIDS, showing the different shared relationships in each case. Each patient is a distinct case, differing in terms of age, financial situation, attitude toward the illness etc., showing the reader that this disease affects all types of people. The book is written in the "no-frills style"