Very early onset inflammatory bowel disease hand, other types of primary immunodeficiency can often manifest with IBD-like symptoms, too. These include the IPEX syndrome, Wiskott-Aldrich syndrome, XIAP syndrome or chronic granulomatous disease. Inflammatory bowel diseases (IBDs), such as Crohn Disease (CD) or Ulcerative Colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract. Up-to-date findings show that the pathogenesis is influenced by both environmental and genetic factors. A considerable number of monogenic disorders can be found especially among patients with VEOIBD. Causal mutations can be found in genes involved in epithelial barrier formation (COL7A1, FERMT1), innate (CYBB, G6PC3), as well as the specific immune response and
Extrapulmonary tuberculosis in the liver or spleen, splenomegaly, splenic or lymph node calcification, inflammatory thickening of the terminal ileum and caecum, patulous I-C junction and lowattenuation lymphadenopathy may help suggest tuberculosis as the etiology of diffuse peritoneal disease. Like tuberculosis, Crohn‟s disease also can result in granulomatous peritonitis13. Smooth and regular peritoneal thickening is more in favor of granulomatous peritonitis. Extrapulmonary tuberculosis Extrapulmonary tuberculosis is tuberculosis (TB) within another location in the body than the lungs. This occurs in 15–20% of active cases, causing other kinds of TB. These are collectively denoted as "extrapulmonary tuberculosis". Extrapulmonary TB occurs more commonly in immunosuppressed