Meg Ryan roles followed, including appearances in "Charles in Charge", "Armed and Dangerous", "Amityville 3-D" and "Promised Land"; for her role in the lattermost she received her first Independent Spirit Award nomination. In 1986, she played Carole Bradshaw, the wife of Naval Flight Officer Nick "Goose" Bradshaw (played by Anthony Edwards) in "Top Gun". Ryan appeared in the film "Innerspace" (1987) with her future husband Dennis Quaid, and later in the remake of "D.O.A." (1988) and in "The Presidio" (1988). Her first leading role was the romantic comedy film "When Harry Met Sally..." (1989), which paired her with comedic leading man Billy
Orgasm them. This delay can lead to frustration of not reaching orgasmic sexual satisfaction. Psychoanalyst Wilhelm Reich, in his 1927 book "Die Funktion des Orgasmus" (published in English in 1980 as "Genitality in the Theory and Therapy of Neurosis") was the first to make orgasm central to the concept of mental health, and defined neurosis in terms of blocks to having orgastic potency. Although orgasm dysfunction can have psychological components, physiological factors often play a role. For instance, delayed orgasm or the inability to achieve orgasm is a common side effect of many medications. Menopause may involve loss of hormones supporting