Very early onset inflammatory bowel disease hand, other types of primary immunodeficiency can often manifest with IBD-like symptoms, too. These include the IPEX syndrome, Wiskott-Aldrich syndrome, XIAP syndrome or chronic granulomatous disease. Inflammatory bowel diseases (IBDs), such as Crohn Disease (CD) or Ulcerative Colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract. Up-to-date findings show that the pathogenesis is influenced by both environmental and genetic factors. A considerable number of monogenic disorders can be found especially among patients with VEOIBD. Causal mutations can be found in genes involved in epithelial barrier formation (COL7A1, FERMT1), innate (CYBB, G6PC3), as well as the specific immune response and
Ovarian disease amounts of male hormones than needed. Causes: The increased level of hormones may result in irregular menstrual cycle and diabetes and heart problem in the long run. It also affects the body in various ways like problem getting pregnant, sleep apnea, depression and anxiety, can enhance the risk of endometrial cancer. Symptoms: Treatment: Other conditions include: Ovarian disease Ovarian diseases are conditions that happen to young women and can affect their reproductive system and general health. These can be classified as endocrine disorders or as a disorders of the reproductive system. If the egg fails to release from the follicle