Mercury silvering methods. The technique was also used in Asia, for example "tokin" plating in Edo-period Japan. Mercury silvering Mercury silvering or fire gilding is a silvering technique for applying a thin layer of precious metal such as silver or gold (mercury gilding) to a base metal object. The process was invented during the Middle Ages and is documented in Vannoccio Biringuccio's 1540 book "De la pirotechnia". An amalgam of mercury and the precious metal is prepared and applied to the object which is then heated, sometimes in oil, vaporizing most of the mercury. The technique is dangerous since mercury is highly
Suzuki reaction the palladium and nickel-catalyzed Suzuki coupling reactions. Apart from Pd and Ni catalyst system, cheap and non-toxic metal sources like iron and copper have been used in Suzuki coupling reaction. The Bedford research group and the Nakamura research group have extensively worked on developing the methodology of iron catalyzed Suzuki coupling reaction. Ruthenium is another metal source that has been used in Suzuki coupling reaction. Nickel catalysis can construct C-C bonds from amides. Despite the inherently inert nature of amides as synthons, the following methodology can be used to prepare C-C bonds. The coupling procedure is mild and tolerant of