Surface area representing a cell as an idealized sphere of radius "r", the volume and surface area are, respectively, "V" = 4/3 π "r"; "SA" = 4 π "r". The resulting surface area to volume ratio is therefore 3/"r". Thus, if a cell has a radius of 1 μm, the SA:V ratio is 3; whereas if the radius of the cell is instead 10 μm, then the SA:V ratio becomes 0.3. With a cell radius of 100, SA:V ratio is 0.03. Thus, the surface area falls off steeply with increasing volume. Surface area The surface area of a solid object is a
Surface and bulk erosion of two separate categories. In surface erosion, the erosion rate is directly proportional to the surface area of the material. For very thin materials, the surface area remains relatively constant when the material degrades, which allows surface erosion to be characterized as zero order release since the rate of degradation is constant. In bulk erosion, the erosion rate depends on the volume of the material. Due to degradation, the volume of the material decreases during bulk erosion causing the erosion rate to decrease over time. Therefore, bulk erosion rates are difficult to control since it is not zero order. To