Spanish East Indies chief consort, and his subjects. Seeking to develop trade between the East Indies and the Americas across the Pacific Ocean, Antonio de Mendoza encouraged the exploration of these Asian territories and commissioned the expedition of Ruy López de Villalobos to the Philippines in 1542–1543. Miguel López de Legazpi set out from Mexico, and established the first Spanish settlement in the Philippines in 1565, which became the town of San Miguel in present-day Cebu. That same year, another member of the expedition, Andrés de Urdaneta discovered a maritime route from the Philippines to Mexico, across the Pacific, leading to the important
Anglo-Spanish War (1654–1660) only Spanish West Indies island that did not have new defensive works. They landed in May 1655 at a place called Santiago de la Vega, now Spanish Town. They came, and they stayed, in the face of prolonged local resistance that was reinforced by troops sent from Spain and New Spain (México). In 1657 the English Governor invited the Buccaneers to base themselves at Port Royal on Santiago, to deter the Spanish from recapturing the island. For England, Jamaica was to be the 'dagger pointed at the heart of the Spanish Empire', although in fact it was a possession of