Amblyomma americanum mammalian meat and meat products. The allergy manifests as anaphylaxis — a life-threatening allergic reaction characterized by constriction of airways and a drop in blood pressure. This response is triggered by an IgE antibody to the mammalian oligosaccharide galactose-alpha-1,3-galactose (alpha-gal). As well as occurring in non-primate mammals, alpha-gal is also found in cat dander and in the drug cetuximab. Allergic reactions to alpha-gal usually occur 3–6 hours after consuming red meat, unlike allergic reactions to other foods, whose onset following consumption is more or less immediate, making it more difficult to identify what caused the reaction. Skin tests with standard
What Is Life in a number of popular movies: Martin Scorsese's "Goodfellas" (1990), during the "May 11, 1980" sequence; Tom Shadyac's "Patch Adams" (1998); and, more recently, Sam Mendes' "Away We Go" (2009). In late 2012, "What Is Life" was used in advance promotion for the film "This Is 40", directed by Judd Apatow, although it was omitted from the accompanying soundtrack album. According to "Rolling Stone": "Today, many people know it merely as a song from all those soundtracks: it's in "This Is 40", "Patch Adams", "Goodfellas" and many more. It's almost as ubiquitous as 'Let My Love Open the Door' or