Radiocarbon dating samples Radiocarbon dating samples Samples used for radiocarbon dating must be handled carefully to avoid contamination. Not all material can be dated by this method; only samples containing organic matter can be tested: the date found will be the date of death of the plants or animals from which the sample originally came. Samples for dating need to be converted into a form suitable for measuring the content; this can mean conversion to gaseous, liquid, or solid form, depending on the measurement technique to be used. Before this can be done, however, the sample must be treated to remove any contamination
Kinetic isotope effect at which the substitution occurs. Interpretation of the leaving group kinetic isotope effects had been difficult at first due to significant contributions from temperature independent factors. Kinetic isotope effects at the α-carbon can be used to develop some understanding into the symmetry of the transition state in S2 reactions, although this kinetic isotope effect is less sensitive than what would be ideal, also due to contribution from non-vibrational factors. A secondary kinetic isotope effect is observed when no bond to the isotopically-labeled atom in the reactant is broken or formed. Secondary kinetic isotope effects tend to be much smaller than