Latex allergy allergy is an IgE (immune) mediated reaction to proteins found in the "Hevea brasiliensis" tree, a type of rubber tree. Testing for type I natural rubber latex allergy is through blood testing to determine if the patient is producing IgE antibodies to latex proteins. Anaphylactic shock can be provoked in allergic persons by the "previous" use of latex in an area: latex is typically powdered to prevent sticking, latex proteins become attached to the particles of powder, and the powder becomes airborne when the latex item is used, triggering potentially life-threatening Type I reactions when the latex-contaminated powder is inhaled
Mazzotti reaction Mazzotti reaction The Mazzotti reaction, first described in 1948, is a symptom complex seen in patients after undergoing treatment of onchocerciasis with the medication diethylcarbamazine (DEC). Mazzotti reactions can be life-threatening, and are characterized by fever, urticaria, swollen and tender lymph nodes, tachycardia, hypotension, arthralgias, oedema, and abdominal pain that occur within seven days of treatment of microfilariasis. The Mazzotti reaction correlates with intensity of infection; however, there are probably multiple infection intensity-dependent mechanisms responsible for mediating this complex reaction. The phenomenon is so common when DEC is used for the treatment of onchocerciasis that this drug is the basis