Inflammatory bowel disease inflammatory changes. Crohn's can affect any part of the gastrointestinal tract, from mouth to anus ("skip lesions"), although a majority of the cases start in the terminal ileum. Ulcerative colitis, in contrast, is restricted to the colon and the rectum. Microscopically, ulcerative colitis is restricted to the mucosa (epithelial lining of the gut), while Crohn's disease affects the full thickness of the bowel wall ("transmural lesions"). Lastly, Crohn's disease and ulcerative colitis present with extra-intestinal manifestations (such as liver problems, arthritis, skin manifestations and eye problems) in different proportions. In 10–15% of cases, a definitive diagnosis neither of Crohn's disease
Sound Affects 1980. In the U.S., the album spent 11 weeks on the "Billboard 200" album charts and reached its peak position of No. 72 in February 1981. The 2010 rerelease also charted in the UK, reaching No. 63 in November of that year. "Sound Affects" was re-issued on 8 November 2010 as a 2 CD Deluxe Edition to celebrate its 30th Anniversary. All songs by Paul Weller except where stated Note ♠ – Tracks previously unreleased Sound Affects Sound Affects is the fifth studio album by British rock band the Jam. The cover art is a pastiche of the artwork used