Burrill Bernard Crohn in New Milford, Connecticut. The Burrill B. Crohn Research Foundation was established at Mount Sinai in 1983 with initial funding from Rose Crohn and later his daughter, Ruth Crohn Dickler. Burrill Bernard Crohn Burrill Bernard Crohn (June 13, 1884 – July 29, 1983) was an American gastroenterologist and made the first major advance to identify the disease that now bears his name. Although the description of Crohn's disease is by far his most famous accomplishment, Crohn had a long career both as a clinician, and as a researcher who contributed to modern understanding of many gastrointestinal conditions. Crohn received his
Chronic granulomatous disease from the name of the disease as children survived into adulthood. Gene therapy is currently being studied as a possible treatment for chronic granulomatous disease. CGD is well-suited for gene therapy since it is caused by a mutation in single gene which only affects one body system (the hematopoietic system). Viruses have been used to deliver a normal gp91 gene to rats with a mutation in this gene, and subsequently the phagocytes in these rats were able to produce oxygen radicals. In 2006, two human patients with X-linked chronic granulomatous disease underwent gene therapy and blood cell precursor stem cell