Paleolithic body paint and perhaps in ritual. Undisputed evidence of art only becomes common in the Upper Paleolithic. Lower Paleolithic Acheulean tool users, according to Robert G. Bednarik, began to engage in symbolic behavior such as art around 850,000 BP. They decorated themselves with beads and collected exotic stones for aesthetic, rather than utilitarian qualities. According to him, traces of the pigment ochre from late Lower Paleolithic Acheulean archaeological sites suggests that Acheulean societies, like later Upper Paleolithic societies, collected and used ochre to create rock art. Nevertheless, it is also possible that the ochre traces found at Lower Paleolithic sites
Lithium (medication) the likelihood of developing depression. People taking lithium thus should routinely be assessed for hypothyroidism and treated with synthetic thyroxine if necessary. Because lithium competes with the receptors for the antidiuretic hormone in the kidney, it increases water output into the urine, a condition called nephrogenic diabetes insipidus. Clearance of lithium by the kidneys is usually successful with certain diuretic medications, including amiloride and triamterene. It increases the appetite and thirst ("polydypsia") and reduces the activity of thyroid hormone (hypothyroidism). The latter can be corrected by treatment with thyroxine and does not require the lithium dose to be adjusted. Lithium