Meg Ryan roles followed, including appearances in "Charles in Charge", "Armed and Dangerous", "Amityville 3-D" and "Promised Land"; for her role in the lattermost she received her first Independent Spirit Award nomination. In 1986, she played Carole Bradshaw, the wife of Naval Flight Officer Nick "Goose" Bradshaw (played by Anthony Edwards) in "Top Gun". Ryan appeared in the film "Innerspace" (1987) with her future husband Dennis Quaid, and later in the remake of "D.O.A." (1988) and in "The Presidio" (1988). Her first leading role was the romantic comedy film "When Harry Met Sally..." (1989), which paired her with comedic leading man Billy
Meg Ryan worldwide. "You've Got Mail" once again paired Ryan with Hanks, earning her a third Golden Globe nomination and making over $250 million worldwide. She also appeared in 1998's "Hurlyburly" with Sean Penn. Ryan's first film of the 2000s was "Hanging Up", a Diane Keaton-directed family comedy-drama about a trio of sisters who bond over the approaching death of their curmudgeonly father. Also starring Keaton, Lisa Kudrow and Walter Matthau, the film adaptation of Delia Ephron's 1995 novel received poor reviews from critics. The same year, Ryan was cast in the action thriller "Proof of Life" with Russell Crowe, directed by