Indian Runner duck the Pekin duck. As soon as the Indian Runners became fashionable, a demand for egg-layers and general purpose breeds developed. Using Runners crossed to Rouens, Aylesburys and Cayugas (the large black American breed), William Cook produced his famous Orpington Ducks. Mrs Campbell crossed her fawn-and-white Runner duck to a Rouen drake to create the Campbell ducks introduced in 1898. Later, she introduced wild mallard blood and managed to create the most prolific egg-layer, the Khaki Campbell (announced in 1901). Other breeds followed, some of which emerged as direct mutations of the Khaki Campbell, along with crosses back to Indian Runners,
History of Rouen 1485 and influenced its cultural and economic development. Rouen became a regional centre of production by introducing a variety of books to the industry. Although it did not have a university, Rouen became an important intellectual centre by reason of its reputed schools of higher learning. In 1734, a school of surgery was founded (second only to that of Paris, founded in 1724). In 1758 a new hospital was opened, to the west of the town, which replaced the old medieval one which had become too small. During the Franco-Prussian War of 1870-1871, Rouen was occupied by the Prussians. During