Omalizumab and the World Health Organization. It is also used to treat people 12 years and above with chronic spontaneous urticaria (also called chronic idiopathic urticaria), which cannot be treated with elevated doses of H1-antihistamines. The main adverse effect is anaphylaxis (a life-threatening systemic allergic reaction), with a rate of occurrence of 1 to 2 patients per 1,000. Like other protein and antibody drugs, omalizumab also causes anaphylaxis, although at a relatively low frequency among antibody drugs. The allergic reaction is probably not due to the binding characteristics of the antibody drug, but to the protein nature of the antibody. The
"K" Is for Killer but from lack of evidence as to cause of death, the official line was that Lorna died naturally, as a result of an allergic reaction. Now someone has sent Janice a tape of a porn movie Lorna apparently made before her death, and Janice, who has coped badly with her daughter's death, wants Kinsey to find out the truth. Mace, Janice's husband, and her two surviving daughters, Berlyn and Trinny, seem less keen on the investigation, and Mace and Berlyn, in particular, become positively hostile to Kinsey as she sets out to find out what happened to Lorna. With some