Spanish East Indies chief consort, and his subjects. Seeking to develop trade between the East Indies and the Americas across the Pacific Ocean, Antonio de Mendoza encouraged the exploration of these Asian territories and commissioned the expedition of Ruy López de Villalobos to the Philippines in 1542–1543. Miguel López de Legazpi set out from Mexico, and established the first Spanish settlement in the Philippines in 1565, which became the town of San Miguel in present-day Cebu. That same year, another member of the expedition, Andrés de Urdaneta discovered a maritime route from the Philippines to Mexico, across the Pacific, leading to the important
Spanish East Indies of Luzon remained outside Spanish control until the early 19th century, and the southernmost tip of Palawan, not until the late 1890s. The rest of Mindanao (Caesarea Karoli)—aside from outposts in Northern Mindanao, Zamboanga, Cotabato, and the islands of Basilan and Jolo, the rest was nominally under Spanish control, recognizing Spanish rule, but left to administer their own affairs, as in the cases of the Sulu, and the Maguindanao sultanates, as well as a number of other Lumad tribes not affiliated with either. Similarly, Palau and the vast majority of the Caroline Islands were not governed by Spanish missions until