Skeleton intervertebral discs. It is not as hard and rigid as bone but is stiffer and less flexible than muscle. Cartilage is composed of specialized cells called chondrocytes that produce a large amount of extracellular matrix composed of Type II collagen (except Fibrocartilage which also contains type I collagen) fibers, abundant ground substance rich in proteoglycan, and elastin fibers. Cartilage is classified in three types, elastic cartilage, hyaline cartilage and fibrocartilage, which differ in the relative amounts of these three main components. Unlike other connective tissues, cartilage does not contain blood vessels. The chondrocytes are supplied by diffusion, helped by the
Tissues and Issues charts. An early batch of the album had print errors on the right and left hand side title faces. The faces had the title "Charlotte Church : Crazy Chick", when it should have been "Charlotte Church : Tissues and Issues". "Tissues and Issues" is Charlotte Church's second and final album with Sony Music UK. Notes Tissues and Issues Tissues and Issues is the fifth studio album by the Welsh singer Charlotte Church released by Sony BMG UK in the United Kingdom on 11 July 2005 (see 2005 in music). Church states that she titled the album "Tissues and Issues" because