Very early onset inflammatory bowel disease hand, other types of primary immunodeficiency can often manifest with IBD-like symptoms, too. These include the IPEX syndrome, Wiskott-Aldrich syndrome, XIAP syndrome or chronic granulomatous disease. Inflammatory bowel diseases (IBDs), such as Crohn Disease (CD) or Ulcerative Colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract. Up-to-date findings show that the pathogenesis is influenced by both environmental and genetic factors. A considerable number of monogenic disorders can be found especially among patients with VEOIBD. Causal mutations can be found in genes involved in epithelial barrier formation (COL7A1, FERMT1), innate (CYBB, G6PC3), as well as the specific immune response and
Supernumerary body part sometimes represented as having numerous breasts. This was particularly notable in the cult of Artemis (Diana) celebrated in the ancient city of Ephesus, in modern Turkey. In Japanese mythology, the god of the sea and storms, Susanoo, is sometimes depicted as having a third arm. In Hungarian mythology, having six fingers on a hand (polydactyly) is held to be the sign of innate supernatural power (see táltos). In the Bible, Goliath has brothers who have six fingers and six toes. Supernumerary body part Supernumerary body parts are most commonly a congenital disorder involving the growth of an additional part of