Atmosphere of Earth and balloons, and too low to permit orbital spacecraft. The mesosphere is mainly accessed by sounding rockets and rocket-powered aircraft. The stratosphere is the second-lowest layer of Earth's atmosphere. It lies above the troposphere and is separated from it by the tropopause. This layer extends from the top of the troposphere at roughly above Earth's surface to the stratopause at an altitude of about . The atmospheric pressure at the top of the stratosphere is roughly 1/1000 the pressure at sea level. It contains the ozone layer, which is the part of Earth's atmosphere that contains relatively high concentrations of
Ozone depletion increases in surface UVB, there is no direct observational evidence linking ozone depletion to higher incidence of skin cancer and eye damage in human beings. This is partly because UVA, which has also been implicated in some forms of skin cancer, is not absorbed by ozone, and because it is nearly impossible to control statistics for lifestyle changes over time. Ozone, while a minority constituent in Earth's atmosphere, is responsible for most of the absorption of UVB radiation. The amount of UVB radiation that penetrates through the ozone layer decreases exponentially with the slant-path thickness and density of the layer.