Radiocarbon dating samples Radiocarbon dating samples Samples used for radiocarbon dating must be handled carefully to avoid contamination. Not all material can be dated by this method; only samples containing organic matter can be tested: the date found will be the date of death of the plants or animals from which the sample originally came. Samples for dating need to be converted into a form suitable for measuring the content; this can mean conversion to gaseous, liquid, or solid form, depending on the measurement technique to be used. Before this can be done, however, the sample must be treated to remove any contamination
Isotope-coded affinity tag of the column. For the quantitative comparison of two proteomes, one sample is labeled with the isotopically light (d0) probe and the other with the isotopically heavy (d8) version. To minimize error, both samples are then combined, digested with a protease (i.e., trypsin), and subjected to avidin affinity chromatography to isolate peptides labeled with isotope-coded tagging reagents. These peptides are then analyzed by liquid chromatography-mass spectrometry (LC-MS). The ratios of signal intensities of differentially mass-tagged peptide pairs are quantified to determine the relative levels of proteins in the two samples. Isotope-coded affinity tag An Isotope-coded affinity tag (ICAT) is an