Burrill Bernard Crohn Burrill Bernard Crohn Burrill Bernard Crohn (June 13, 1884 – July 29, 1983) was an American gastroenterologist and made the first major advance to identify the disease that now bears his name. Although the description of Crohn's disease is by far his most famous accomplishment, Crohn had a long career both as a clinician, and as a researcher who contributed to modern understanding of many gastrointestinal conditions. Crohn received his bachelor's degree from City College of New York in 1902. He received a medical degree from Columbia University College of Physicians and Surgeons in 1907. Crohn first became an intern
Adult polyglucosan body disease Adult polyglucosan body disease Adult polyglucosan body disease (APBD) is an orphan disease and a glycogen storage disorder that is caused by an inborn error of metabolism. Symptoms can emerge any time after the age of 30; early symptoms include trouble controlling urination, trouble walking, and lack of sensation in the legs. People eventually develop dementia. A person inherits loss-of-function mutations in the "GBE1" gene from each parent, and the lack of glycogen branching enzyme (the protein encoded by "GNE1") leads to buildup of unbranched glycogen in cells, which harms neurons more than other kinds of cells. Most people first