Meg Ryan roles followed, including appearances in "Charles in Charge", "Armed and Dangerous", "Amityville 3-D" and "Promised Land"; for her role in the lattermost she received her first Independent Spirit Award nomination. In 1986, she played Carole Bradshaw, the wife of Naval Flight Officer Nick "Goose" Bradshaw (played by Anthony Edwards) in "Top Gun". Ryan appeared in the film "Innerspace" (1987) with her future husband Dennis Quaid, and later in the remake of "D.O.A." (1988) and in "The Presidio" (1988). Her first leading role was the romantic comedy film "When Harry Met Sally..." (1989), which paired her with comedic leading man Billy
Orgasm have shown that the pleasure centers of a man's brain show more intense activity than in women during orgasm. Human brain wave patterns show distinct changes during orgasm, which indicate the importance of the limbic system in the orgasmic response. Male and female brains demonstrate similar changes during orgasm, with brain activity scans showing a temporary decrease in the metabolic activity of large parts of the cerebral cortex with normal or increased metabolic activity in the limbic areas of the brain. EEG tracings from volunteers during orgasm were first obtained by Mosovich and Tallaferro in 1954. These research workers recorded