Omalizumab and the World Health Organization. It is also used to treat people 12 years and above with chronic spontaneous urticaria (also called chronic idiopathic urticaria), which cannot be treated with elevated doses of H1-antihistamines. The main adverse effect is anaphylaxis (a life-threatening systemic allergic reaction), with a rate of occurrence of 1 to 2 patients per 1,000. Like other protein and antibody drugs, omalizumab also causes anaphylaxis, although at a relatively low frequency among antibody drugs. The allergic reaction is probably not due to the binding characteristics of the antibody drug, but to the protein nature of the antibody. The
What Is Life in a number of popular movies: Martin Scorsese's "Goodfellas" (1990), during the "May 11, 1980" sequence; Tom Shadyac's "Patch Adams" (1998); and, more recently, Sam Mendes' "Away We Go" (2009). In late 2012, "What Is Life" was used in advance promotion for the film "This Is 40", directed by Judd Apatow, although it was omitted from the accompanying soundtrack album. According to "Rolling Stone": "Today, many people know it merely as a song from all those soundtracks: it's in "This Is 40", "Patch Adams", "Goodfellas" and many more. It's almost as ubiquitous as 'Let My Love Open the Door' or