Estelle Reiner Harry Met Sally...", in which director Rob Reiner cast his mother as a customer in a scene with stars Billy Crystal and Meg Ryan at Katz's Delicatessen, in which Ryan fakes what was described as "a very public (and very persuasive) orgasm". Approached by a waitress after Ryan finishes, Reiner deadpans "I’ll have what she’s having". The line was ranked 33rd on the American Film Institute's list of the Top 100 movie quotations, just behind "Casablanca"'s "Round up the usual suspects". Reiner died of natural causes on October 25, 2008 at age 94 in her home in Beverly Hills, California.
Meg Ryan productions in the early 2010s—including the ensemble drama "Lives of The Saints" opposite Kat Dennings, Kevin Zegers, and John Lithgow, and "Long Time Gone", a film adaptation of the April Stevens novel "Angel Angel",—all of which failed to materialize. In April 2011, it was announced that Ryan would make her feature film directing debut with a film titled "Into the Beautiful", described as "a contemporary "Big Chill" with longtime friends reconnecting", but it also was never made. In October 2012, Ryan was featured in the PBS documentary "Half the Sky: Turning Oppression into Opportunity for Women Worldwide". The series introduces