Amblyomma americanum mammalian meat and meat products. The allergy manifests as anaphylaxis — a life-threatening allergic reaction characterized by constriction of airways and a drop in blood pressure. This response is triggered by an IgE antibody to the mammalian oligosaccharide galactose-alpha-1,3-galactose (alpha-gal). As well as occurring in non-primate mammals, alpha-gal is also found in cat dander and in the drug cetuximab. Allergic reactions to alpha-gal usually occur 3–6 hours after consuming red meat, unlike allergic reactions to other foods, whose onset following consumption is more or less immediate, making it more difficult to identify what caused the reaction. Skin tests with standard
What Is Life? his 1922 article "Variation due to Change in the Individual Gene" already laid out all the basic properties of the "heredity molecule" (then not yet known to be DNA) that Schrödinger was to re-derive in 1944 "from first principles" in "What is Life?" (including the "aperiodicity" of the molecule), properties which Muller specified and refined additionally in his 1929 article "The Gene As The Basis of Life" and during the 1930s. Moreover, H. J. Muller himself wrote in a 1960 letter to a journalist regarding "What Is Life?" that whatever the book got right about the "hereditary molecule" had already