21st-century fossil fuel regulations in the United States spill has been the Deepwater Horizon spill of 2010. With the exception of Kalamazoo River (2010), all other major spills have occurred around the Gulf of Mexico. In May 2010, the United States Department of the Interior called for an end to drilling in the area of the Deepwater Horizon spill. Despite pushback from oil companies and states, the Supreme Court ruled to keep the moratorium in place until October 2010. BP agreed to financial compensation for the damage they caused, including payouts to the Deepwater Horizon Oil Spill Trust. Regulations drafted after the accident required oil companies to update
Health consequences of the Deepwater Horizon oil spill fetuses. For example, 2-butoxyethanol is a human health hazard substance; it is a fetal toxin and it breaks down blood cells, causing blood and kidney disorders". Louisianan's Governor Bobby Jindal said those impacted will be compensated by BP. An RNA sequencing study found that a combination of Corexit and oil may weaken the cell junctions of airway epithelial cells, which is seen in asthma and cystic fibrosis. The authors of this study posit that the results of this RNA transcriptomic study could provide evidence for the mechanisms through which BP oil spill workers experienced respiratory oxidative stress and associated symptoms.