Chimera (mythology) (that does not occur with depictions of male lions). Sighting the Chimera was an omen of storms, shipwrecks, and natural disasters (particularly volcanoes). While there are different genealogies, in one version the Chimera mated with her brother Orthrus and was the mother of the Sphinx and the Nemean lion (others have Orthrus and their mother, Echidna, mating; most attribute all to Typhon and Echidna). The Chimera finally was defeated by Bellerophon with the help of Pegasus, at the command of King Iobates of Lycia, after terrorizing Lycia and nearby lands. Since Pegasus could fly, Bellerophon shot the Chimera from the
Zinc finger chimera Zinc finger chimera Zinc finger protein chimera are chimeric proteins composed of a DNA-binding zinc finger protein domain and another domain through which the protein exerts its effect. The effector domain may be a transcriptional activator (A) or repressor (R), a methylation domain (M) or a nuclease (N). Modification of the endogenous DNA-binding zinc finger domain is the basis of the most advanced field in construction of gene-specific artificial transcription factors. Linking together six ZFPs produces a target-site of 18-19 bp. Assuming specificity to that one sequence and that the sequence of the genome is random, 18 bp is long