Estelle Reiner Harry Met Sally...", in which director Rob Reiner cast his mother as a customer in a scene with stars Billy Crystal and Meg Ryan at Katz's Delicatessen, in which Ryan fakes what was described as "a very public (and very persuasive) orgasm". Approached by a waitress after Ryan finishes, Reiner deadpans "I’ll have what she’s having". The line was ranked 33rd on the American Film Institute's list of the Top 100 movie quotations, just behind "Casablanca"'s "Round up the usual suspects". Reiner died of natural causes on October 25, 2008 at age 94 in her home in Beverly Hills, California.
Orgasm have shown that the pleasure centers of a man's brain show more intense activity than in women during orgasm. Human brain wave patterns show distinct changes during orgasm, which indicate the importance of the limbic system in the orgasmic response. Male and female brains demonstrate similar changes during orgasm, with brain activity scans showing a temporary decrease in the metabolic activity of large parts of the cerebral cortex with normal or increased metabolic activity in the limbic areas of the brain. EEG tracings from volunteers during orgasm were first obtained by Mosovich and Tallaferro in 1954. These research workers recorded