Omalizumab and the World Health Organization. It is also used to treat people 12 years and above with chronic spontaneous urticaria (also called chronic idiopathic urticaria), which cannot be treated with elevated doses of H1-antihistamines. The main adverse effect is anaphylaxis (a life-threatening systemic allergic reaction), with a rate of occurrence of 1 to 2 patients per 1,000. Like other protein and antibody drugs, omalizumab also causes anaphylaxis, although at a relatively low frequency among antibody drugs. The allergic reaction is probably not due to the binding characteristics of the antibody drug, but to the protein nature of the antibody. The
What Is Life love song – perhaps a "lovingly crafted paen" to Harrison's wife Pattie, as Alan Clayson puts it – or a devotional song like many of Harrison's compositions. Ian Inglis writes that the song title suggests a "philosophical debate about the meaning of life", yet its rendering as ""what is my life"" in the choruses "reshapes [the meaning] completely". Theologian Dale Allison finds no religious content in "What Is Life" but notes the "failure of words to express feelings" implied in the opening line (""What I feel, I can't say""), a recurring theme of Harrison's spiritual songs such as "That Is