Omalizumab and the World Health Organization. It is also used to treat people 12 years and above with chronic spontaneous urticaria (also called chronic idiopathic urticaria), which cannot be treated with elevated doses of H1-antihistamines. The main adverse effect is anaphylaxis (a life-threatening systemic allergic reaction), with a rate of occurrence of 1 to 2 patients per 1,000. Like other protein and antibody drugs, omalizumab also causes anaphylaxis, although at a relatively low frequency among antibody drugs. The allergic reaction is probably not due to the binding characteristics of the antibody drug, but to the protein nature of the antibody. The
What Is Life a descending guitar riff, it is one of Harrison's most popular compositions and was a regular inclusion in his live performances. "Rolling Stone" magazine has variously described it as a "classic" and an "exultant song of surrender". "What Is Life" has appeared in the soundtrack for feature films such as "Goodfellas" (1990), "Patch Adams" (1998), "Big Daddy" (1999), "Away We Go" (2009), "This Is 40" (2012) and "Instant Family" (2018). Harrison's original recording was included on the compilations "The Best of George Harrison" and "", and live versions appear on his album "Live in Japan" (1992) and in Martin Scorsese's