Omalizumab and the World Health Organization. It is also used to treat people 12 years and above with chronic spontaneous urticaria (also called chronic idiopathic urticaria), which cannot be treated with elevated doses of H1-antihistamines. The main adverse effect is anaphylaxis (a life-threatening systemic allergic reaction), with a rate of occurrence of 1 to 2 patients per 1,000. Like other protein and antibody drugs, omalizumab also causes anaphylaxis, although at a relatively low frequency among antibody drugs. The allergic reaction is probably not due to the binding characteristics of the antibody drug, but to the protein nature of the antibody. The
Red imported fire ant Some victims may develop a more serious allergic reaction which can be life-threatening. The venom is mainly composed of insoluble alkaloids with a minor watery phase containing some 46 proteins of which four are reported as allergens. Because of their notoriety and invasive behaviour, red imported fire ants are considered pests. In the United States, the Food and Drug Administration estimates more than $5 billion is spent annually on medical treatment, damage, and control in infested areas. They can also cause $2.5 billion in damages annually in just 20 years. In Texas alone, red imported fire ants caused $300 million