Spanish East Indies together with the Spanish West Indies, were administered through the Viceroyalty of New Spain based in Mexico City. After Mexican independence, they were ruled directly from Madrid. As a result of the Spanish–American War in 1898, the Philippines and Guam were occupied by the United States while about 6,000 of the remaining smaller islands were sold to Germany in the German–Spanish Treaty of 1899. The few remaining islands were ceded to the United States when the Treaty of Washington was ratified in 1901. Spanish contact began on , when a Spanish expedition led by Ferdinand Magellan reached the Mariana Islands.
East Indies World was initially thought to be the easternmost part of the "Indies" by explorer Christopher Columbus, who had grossly underestimated the westerly distance from Europe to Asia. Later, to avoid confusion, the New World came to be called the "West Indies", while the original Indies came to be called the "East Indies". The designation "East Indian" was once primarily used to describe people of all of the East Indies, in order to avoid the potential confusion from the term American Indian who were once simply referred to as "Indians" (see the Native American name controversy for more information). East Indies