Burrill Bernard Crohn with inflammatory bowel disease, including Crohn's disease. He was elected president of the American Gastroenterological Association in 1932. He received numerous awards and professional honors, wrote extensively for doctors and the general public, and was asked to consult on high-profile patients from all over the US and abroad, including President Dwight D. Eisenhower in 1956. During his career, Crohn wrote three books, "Affections of the Stomach" (1927), "Understand Your Ulcer" (1943), and "Regional Ileitis" (1947, second edition 1958). He also wrote more than 100 articles for professional journals. When asked why he went into medicine, Crohn said he wanted to
Adult polyglucosan body disease shortage (deficiency) of the glycogen branching enzyme, which leads to the production of abnormal glycogen molecules. These abnormal glycogen molecules, called polyglucosan bodies, accumulate within cells and cause damage. Neurons appear to be particularly vulnerable to the accumulation of polyglucosan bodies in people with this disorder, leading to impaired neuronal function. Some mutations in the "GBE1" gene that cause adult polyglucosan body disease do not result in a shortage of glycogen branching enzyme. In people with these mutations, the activity of this enzyme is normal. How mutations cause the disease in these individuals is unclear. Other people with adult polyglucosan