Burrill Bernard Crohn published paper was "Regional Ileitis: A Pathologic and Clinical Entity". Crohn's work helped correct the thinking that the ailment was actually a form of tuberculosis rather than an inflammatory disease of the gastrointestinal tract. Crohn's work built on the work of Dr. Kennedy Dalziel of Glasgow into regional enteritis twenty years earlier. Crohn always preferred the medically descriptive terms "regional ileitis" and "regional enteritis" to "Crohn's disease", but he was not able to prevent the appropriation of his name for the disease. Some of Crohn's initial research into the causes of the Crohn's disease was centered around his personal conviction
Dent's disease more fully described the disease. Wrong had studied with Dent and chose to name the disease after his mentor. Dent's disease is a genetic disorder caused by mutations in the gene "CLCN5", which encodes a kidney-specific voltage-gated chloride channel, a 746-amino-acid protein (CLC-5) with 12 to 13 transmembrane domains. It manifests itself through low-molecular-weight proteinuria, hypercalciuria, aminoaciduria and hypophosphataemia. Because of its rather rare occurrence, Dent's disease is often diagnosed as idiopathic hypercalciuria, i.e., excess calcium in urine with undetermined causes. Dent's disease Dent's disease (or Dent disease) is a rare X-linked recessive inherited condition that affects the proximal renal