Laughing Gas (1914 film) squabbling. The dentist arrives, and his first patient goes in, obviously in pain. The dentist prepares the nitrous oxide anaesthesic (also known commonly as "laughing gas" due to its effects prior to and after unconsciousness). With the man unconscious he pulls his tooth, but then he can't get him to wake up. He calls for Charlie and when he arrives the dentist runs off. Charlie tries to wake him and eventually tries hitting his head with a mallet. The man revives but starts laughing. Charlie knocks him out with the mallet. The dentist then returns and Charlie is sent to
Substance use disorder addiction, substance dependence, or both. Medically, physiologic dependence requires the development of tolerance leading to withdrawal symptoms. Both abuse and dependence are distinct from addiction which involves a compulsion to continue using the substance despite the negative consequences, and may or may not involve chemical dependency. Dependence often implies abuse, but abuse frequently occurs without dependence, particularly when an individual first begins to abuse a substance. Dependence involves physiological processes while substance abuse reflects a complex interaction between the individual, the abused substance and society. Substance abuse is sometimes used as a synonym for drug abuse, drug addiction, and chemical