Helenus found the city of Buthrotum. After Neoptolemus left Epirus, he left Andromache and their sons in Helenus's care. Neoptolemus was killed by Orestes, Agamemmon's son, in dispute over Hermione, the daughter of Menelaus and Helen, whom Orestes had been promised as wife, but whom Neoptolemus had taken. As the kingdom of Neoptolemus was partitioned, this led to Helenus acquiring the rule of Buthrotum, as king. "Helenus, a son of Priam, was king over these Greek cities of Epirus, having succeeded to the throne and bed of Neoptolemus." Andromache bore him a son, Cestrinus, who is identified with Genger or Zenter,
Neoptolemus (general) might have been a "strategos" rather than a satrap. Neoptolemus managed only to create havoc in Armenia, which suggests that he wasn't cooperating with any existing satrap. As Neoptolemus had a reputation of being restless and unsettled, Perdiccas regarded him with suspicion. So in 321 BC, when Perdiccas set out for Ptolemaic Egypt, he placed Neoptolemus under the command of Eumenes, who was told to exercise particular vigilance regarding Neoptolemus. Perdiccas' suspicions turned out to be well founded: Neoptolemus immediately entered into correspondence with the hostile Macedonian leaders, Antipater and Craterus, and, on being ordered by Eumenes to join him