Meg Ryan Meg Ryan Meg Ryan (born Margaret Mary Emily Anne Hyra; November 19, 1961) is an American actress and producer. Ryan began her acting career in 1981 in minor roles before joining the cast of the CBS soap opera "As the World Turns" in 1982. Subsequently, she began to appear in supporting roles in films during the mid 1980s, achieving recognition in independent films such as "Promised Land" (1988) before her performance in the Rob Reiner-directed romantic comedy "When Harry Met Sally..." (1989) brought her widespread attention and her first Golden Globe nomination. Ryan subsequently established herself, both nationally and internationally,
Orgasm correlating orgasm and brain activity in real time. One study examined 12 healthy women using a positron emission tomography (PET) scanner while they were being stimulated by their partners. Brain changes were observed and compared between states of rest, sexual stimulation, faked orgasm, and actual orgasm. Differences were reported in the brains of men and women during stimulation. However, changes in brain activity were observed in both sexes in which the brain regions associated with behavioral control, fear and anxiety shut down. Regarding these changes, Gert Holstege said in an interview with "The Times", "What this means is that deactivation,