Portrait painting benefitted greatly from such commissions and from the general appreciation of art by bourgeois clients, who supported portraiture as well as still-life and landscapes painting. In addition, the first significant art and dealer markets flourished in Holland at that time. With plenty of demand, Rembrandt was able to experiment with unconventional composition and technique, such as chiaroscuro. He demonstrated these innovations, pioneered by Italian masters such as Caravaggio, most notably in his famous "Night Watch" (1642). "The Anatomy Lesson of Dr. Tulp" (1632) is another fine example of Rembrandt's mastery of the group painting, in which he bathes the corpse
The Doctor (Doctor Who) to the anaesthetics affecting his physiology (1996 "Doctor Who" television film). While his regeneration first appeared to be smooth ("The Parting of the Ways"), the Tenth Doctor began to experience spasms and became somewhat manic, frightening his companion as he pushed the TARDIS to dangerous extremes (). After crash-landing the TARDIS, the Doctor collapsed and remained unconscious for most of the next fifteen hours ("The Christmas Invasion"). The experience was traumatic enough to cause one of his hearts to temporarily stop beating. The TARDIS appears to aid in the regenerative process, with few occasions where the Doctor regenerates outside it.