Iodine deficiency 15–20 mg of iodine in the human body which is primarily concentrated in thyroid tissue and hormones, but 30% of iodine is distributed in other tissues, including mammary glands, eyes, gastric mucosa, choroid plexus, arterial walls, the cervix, and salivary glands. In the cells of these tissues, iodide enters directly by sodium-iodide symporter (NIS). The diagnostic workup of a suspected iodine deficiency includes signs and symptoms as well as possible risk factors mentioned above. A 24-hour urine iodine collection is a useful medical test, as approximately 90% of ingested iodine is excreted in the urine. For the standardized 24-hour test,
Tincture of iodine Tincture of iodine Tincture of iodine, iodine tincture, or weak iodine solution is an antiseptic. It is usually 2–7% elemental iodine, along with potassium iodide or sodium iodide, dissolved in a mixture of ethanol and water. Tincture solutions are characterized by the presence of alcohol. It was used from 1908 in pre-operative skin preparation by surgeon Antonio Grossich. In the United Kingdom the development of an iodine solution for skin sterilisation was pioneered by Lionel Stretton. The "British Medical Journal" published the detail of his work at Kidderminster Infirmary in 1909. Stretton used a much weaker solution than that used