Jennifer Jason Leigh becomes a junkie and falls in love with her partner, played by Jason Patric. Her next film, "Single White Female" (1992), was a surprise box-office success, bringing Leigh to her largest mainstream audience yet, portraying a mentally ill woman who terrorizes roommate Bridget Fonda. Leigh was awarded the MTV Movie Award for Best Villain and nominated for Chicago Film Critics Association Award for Best Actress. Leigh co-starred with Kathy Bates as a tormented, pill-popping woman hiding a history of childhood sexual abuse in the adaptation of Stephen King's novel "Dolores Claiborne" (1995). Leigh achieved her greatest acclaim in the role
Jennifer Jason Leigh "Eyes Wide Shut" (1999) as a grieving patient of Dr. Bill Harford (Tom Cruise) who declares her love for him after her father's death. Kubrick wanted to reshoot the scenes, but Leigh was unavailable due to scheduling conflicts with "eXistenZ"; instead her scenes were cut. Leigh was originally cast as Vincent Gallo's girlfriend in his self-directed film "The Brown Bunny", and was apparently prepared to perform oral sex on Gallo as the script required. Leigh subsequently commented that "it just didn't work out" and the role was eventually played by Chloë Sevigny. In 1997, she was featured in Faith No