Povidone-iodine in people with thyroid problems. Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine. It contains from 9% to 12% available iodine. It works by releasing iodine which results in the death of a range of microorganisms. Povidone-iodine came into commercial use in 1955. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Povidone-iodine is available over the counter. The wholesale cost in the developing world is about 3.30 to 11.40 per liter of 10% solution. This amount in the United Kingdom cost the
Iodine whose main product is sodium nitrate. In total, they can contain at least 0.02% and at most 1% iodine by weight. Sodium iodate is extracted from the caliche and reduced to iodide by sodium bisulfite. This solution is then reacted with freshly extracted iodate, resulting in comproportionation to iodine, which may be filtered off. The caliche was the main source of iodine in the 19th century and continues to be important today, replacing kelp (which is no longer an economically viable source), but in the late 20th century brines emerged as a comparable source. The Japanese Minami Kanto gas field