BCG vaccine fine powder. Sometimes the powder is sealed with vacuum in a glass ampoule. Such a glass ampoule has to be opened slowly to prevent the airflow from blowing out the powder. Then the powder has to be diluted with saline water before injecting. The history of BCG is tied to that of smallpox. Jean Antoine Villemin first recognized bovine tuberculosis in 1854 and transmitted it, and Robert Koch first distinguished "Mycobacterium bovis" from "Mycobacterium tuberculosis". Following the success of vaccination in preventing smallpox, established during the 18th century, scientists thought to find a corollary in tuberculosis by drawing a parallel
Inoculation theory well as increasing the likelihood that talk will generate a potentially viral effect–spreading inoculation to others through the act of vocal talk (Ivanov et al., 2012). Inoculation theory Inoculation theory was developed by social psychologist William J. McGuire in 1961 to explain how attitudes and beliefs change, and more importantly, how to keep existing attitudes and beliefs consistent in the face of attempts to change them. Inoculation theory functions as a strategy to protect attitudes from change–to confer resistance to counter-attitudinal influences, whether such influences take the form of direct attacks or sustained pressures. The theory posits that weak counterarguments–arguments