BCG vaccine produce BCG. Along with supply availability from existing manufacturers, and a "new WHO prequalified vaccine" the total supply will be "sufficient to meet both suppressed 2015 demand carried over to 2016, as well as total forecast demand through 2016-2018." In the fall of 2011, the Sanofi Pasteur plant flooded causing problems with mold. The facility, located in Toronto, Ontario, Canada, produced BCG vaccine products, made with substrain Connaught, such as a tuberculosis vaccine ImmuCYST, a BCG Immunotherapeutic – a bladder cancer drug. By April 2012 the FDA had found dozens of documented problems with sterility at the plant including mold,
Inoculation theory counterarguments, the inoculation receiver will then seek out supporting information to further strengthen their threatened position. Finally, the held attitude or belief becomes resistant to a stronger attack, hence the medical analogy of a vaccine. Inoculation is a theory developed to strengthen existing attitudes and beliefs while building resistance to future counterarguments. For inoculation to be successful it is crucial that a threat (motivation for resistance) is imposed upon these existing ideas and refutational preemption (ability to build defenses against potential counterarguments) takes place after the inoculation. The argument that is presented through inoculation must be strong enough to initiate