A Shot in the Dark (1964 film) adapted from the French play "L'Idiote" by Marcel Achard. The film was released only a few months after the first Clouseau film, "The Pink Panther". Inspector Clouseau (Peter Sellers) of the Sûreté, the French national police, is called to the country home of millionaire Benjamin Ballon (George Sanders) to investigate the murder of his chauffeur, Miguel Ostos. The chauffeur was having an affair with one of the maids, Maria Gambrelli (Elke Sommer), and attacked her in her bedroom after she broke off with him. Miguel was shot and killed in her bedroom and Maria was found with the smoking gun
Lost to follow-up are deceased. Patients who become lost to follow-up during a clinical research trial result in many negative effects on the outcome of the trial and on the pharmaceutical company sponsoring the clinical research trial. Patients who are lost-to-follow-up lead to incomplete study results, which in turn can put a bias on the result of the study as well as a bias on the investigational study medication. A lack of complete results leads to intensified FDA scrutiny of the particular study drug, as well as the pharmaceutical company sponsoring the clinical research study. Biased study outcomes also lead to issues of