Iodine-131 and/or worsen hyperthyroidism and hypothyroidism respectively, and ultimately cause temporary or even permanent thyroid conditions. It can also cause sialadenitis (an inflammation of the salivary gland), gastrointestinal disturbances, allergic reactions and rashes. Potassium iodide is also not recommended for those who have had an allergic reaction to iodine, and people with dermatitis herpetiformis and hypocomplementemic vasculitis, conditions that are linked to a risk of iodine sensitivity. The use of a particular "iodine tablet" used in portable water purification has also been determined as somewhat effective at reducing radioiodine uptake. In a small study on human subjects who, for each of
Isotopes of iodine and 1970s reached about 10). I differs from Cl in that its half-life is longer (15.7 vs. 0.301 million years), it is highly biophilic, and occurs in multiple ionic forms (commonly, I and IO), which have different chemical behaviors. This makes it fairly easy for I to enter the biosphere as it becomes incorporated into vegetation, soil, milk, animal tissue, etc. Of the many isotopes of iodine, only two are typically used in a medical setting: iodine-123 and iodine-131. Since I has both a beta and gamma decay mode, it can be used for radiotherapy or for imaging. I, which