Congenital iodine deficiency syndrome Congenital iodine deficiency syndrome Congenital iodine deficiency syndrome, previously known as cretinism, is a condition of severely stunted physical and mental growth owing to untreated congenital deficiency of thyroid hormone (congenital hypothyroidism) usually owing to maternal hypothyroidism. Around the world, the most common cause of congenital hypothyroidism is iodine deficiency. It has affected many people worldwide and continues to be a major public health problem in many countries. Iodine is an essential trace element, necessary primarily for the synthesis of thyroid hormones. Iodine deficiency is the most common preventable cause of brain damage worldwide. Although iodine is found in many
Iodine monofluoride −45 °C in CClF: It can also be generated by the reaction of iodine with iodine trifluoride at −78 °C in CClF: The reaction of iodine with silver(I) fluoride at 0 °C also yields iodine monofluoride: Iodine monofluoride is used to produce pure nitrogen triiodide: Iodine monofluoride Iodine monofluoride is an interhalogen compound of iodine and fluorine with formula IF. It is a chocolate-brown solid that decomposes at 0 C, disproportionating to elemental iodine and iodine pentafluoride: However, its molecular properties can still be precisely determined by spectroscopy: the iodine-fluorine distance is 190.9 pm and the I−F bond dissociation energy