BCG vaccine produce BCG. Along with supply availability from existing manufacturers, and a "new WHO prequalified vaccine" the total supply will be "sufficient to meet both suppressed 2015 demand carried over to 2016, as well as total forecast demand through 2016-2018." In the fall of 2011, the Sanofi Pasteur plant flooded causing problems with mold. The facility, located in Toronto, Ontario, Canada, produced BCG vaccine products, made with substrain Connaught, such as a tuberculosis vaccine ImmuCYST, a BCG Immunotherapeutic – a bladder cancer drug. By April 2012 the FDA had found dozens of documented problems with sterility at the plant including mold,
Inoculation theory Inoculation in this area improves peoples resistance to such attacks, examples and directions for future work are provided. Recent studies have approached inoculation by incorporating psychological reactance theory (Brehm, 1966, 1972; Brehm & Brehm, 1981) as a means to enhance resistance outcomes through inoculation theory's two key components: threat and refutational preemption. Miller, et al. (2013) focused their study on emerging adults and their reactance to persuasive appeals. Research has demonstrated that this population is in a transitional stage in life (Voyer et al., 2005) and are more likely to defend their behavioral freedoms if they feel others are attempting