Povidone-iodine is also efficient against fungi and viruses (including HIV and "Herpes simplex"). It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone-iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. There is tentative evidence that chlorhexidine and denatured alcohol used to clean skin prior to surgery is better than povidone-iodine with alcohol; however, the evidence is not strong enough as of 2015 to determine routine practice. PVP-I is contraindicated in patients with hyperthyroidism (overactive thyroid gland) and other diseases of the thyroid,
Iodine pentafluoride forming nitriles after hydrolysis with water: Iodine pentafluoride is available as a "Special Gas" for flooding into the atmosphere of the escape shuttle in the terminal sequence of 1979 film Alien. Iodine pentafluoride Iodine pentafluoride is an interhalogen compound with chemical formula IF. It is a fluoride of iodine. It is a colorless or yellow liquid with a density of 3.250 g cm. It was first synthesized by Henri Moissan in 1891 by burning solid iodine in fluorine gas. This exothermic reaction is still used to produce iodine pentafluoride, although the reaction conditions have been improved. Iodine pentafluoride is a