Iodine deficiency iodate as dough conditioner in bread and baked goods was gradually replaced by the use of other conditioning agents such as bromide. Iodine deficiency resulting in goiter occurs in 187 million people globally (2.7% of the population). It resulted in 2700 deaths in 2013 up from 2100 deaths in 1990. A low amount of thyroxine (one of the two thyroid hormones) in the blood, due to lack of dietary iodine to make it, gives rise to high levels of thyroid stimulating hormone (TSH), which stimulates the thyroid gland to increase many biochemical processes; the cellular growth and proliferation can result
Lugol's iodine 126.5 mg/mL. The 15% solution thus has a total iodine content of 6.32 mg per drop of 0.05 mL; the 2% solution has 0.84 mg total iodine content per drop. Potassium iodide renders the elementary iodine soluble in water through the formation of the triiodide () ion. It is not to be confused with tincture of iodine solutions, which consist of elemental iodine, and iodide salts dissolved in water and alcohol. Lugol's solution contains no alcohol. Other names for Lugol's solution are (iodine-potassium iodide); Markodine, Strong solution (Systemic); and Aqueous Iodine Solution BP. In the United Kingdom the NHS pays