Povidone-iodine after treatment with radioiodine, and in patients with dermatitis herpetiformis (Duhring's disease). The sensitization rate to the product is 0.7%. The iodine in PVP-I reacts with hydrogen peroxide, silver, taurolidine and proteins such as enzymes, rendering them (and itself) ineffective. It also reacts with many mercury compounds, giving the corrosive compound mercury iodide, as well as with many metals, making it unsuitable for disinfecting metal piercings. Iodine is absorbed into the body to various degrees, depending on application area and condition of the skin. As such, it interacts with diagnostic tests of the thyroid gland such as radioiodine diagnostics, as
Isotopes of iodine for the so-called iodine pit phenomenon. In addition to commercial production, I (half-life 8 days) is one of the common radioactive fission-products of nuclear fission, and is thus produced inadvertently in very large amounts inside nuclear reactors. Due to its volatility, short half-life, and high abundance in fission products, I, (along with the short-lived iodine isotope I from the longer-lived Te with a half-life of 3 days) is responsible for the largest part of radioactive contamination during the first week after accidental environmental contamination from the radioactive waste from a nuclear power plant. Radioisotopes of iodine are called radioactive iodine