BCG vaccine nesting birds and rusted electrical conduits. The resulting closure of the plant for over two years resulting in shortages of bladder cancer and tuberculosis vaccines. On October 29, 2014 Health Canada gave the permission for Sanofi to resume production of BCG. The global supply situation was analyzed in 2017 and concluded that the global supply is sufficient to meet forecasted BCG vaccine demand but risks for shortages remain mainly due to supply concentration. A weakened strain of bovine tuberculosis bacillus, "Mycobacterium bovis" is specially subcultured in a culture medium, usually Middlebrook 7H9. Some BCG vaccines are freeze dried and become
Inoculation theory (1995) posited that the use of inoculation strategies for these types of campaigns should be utilized to enhance the corporations' credibility and aide in maintaining the existing consumer attitude. This strategy should not be used to change consumer attitudes. Based on the analysis of previous research Burgoon et al. concluded issue/advocacy advertising is most effective for reinforcing support and avoid potential slippage in the attitudes of supporters. Based on previous publications they looked to test three hypotheses. The first was that issue/advocacy advertisements work to inoculate against counterattitudinal attacks. Next, issue/advocacy advertisements work to protect the source credibility. Lastly, conservatives