A Shot in the Dark (1964 film) him to take over as director of "A Shot in the Dark" from Anatole Litvak. Edwards declined initially, but eventually relented under pressure on the condition he could rewrite the script and substitute Inspector Clouseau for the lead character and choreograph comic scenes on the fly as he and Sellers had successfully done for their previous film. The relationship between Edwards and Sellers deteriorated to such a point that at the conclusion of the film they vowed never to work together again. They eventually reconciled to collaborate successfully four years later on "The Party", and on three more "Pink Panther"
Lost to follow-up institutions like the FDA taken action over the recovery of or communication with patients lost-to-follow-up. Section 4.3.4 of the ICH E-6 Good Clinical Practice: Consolidated Guidance reads, "Although a subject is not obliged to give his/her reason(s) for withdrawing prematurely from a trial, the investigator should make a reasonable effort to ascertain the reason(s), while fully respecting the subject's rights." This excerpt expresses the need for physicians associated with clinical research trials to make a first-hand effort to contact patients who are lost-to-follow-up. In doing so pharmaceutical companies not only look out for the best interest of the patients who