Iodine-125 electrons from the radioisotope have been found in one study to do little cellular damage, unless the radionuclide is incorporated chemically directly into cellular DNA, which is not the case for present radiopharmaceuticals which use I-125 as the radioactive label nuclide. As with other radioisotopes of iodine, iodine-125 uptake in the body (mostly to the thyroid) can be blocked with prompt administration of stable iodine-127 in the form of an iodide or iodate salt. Potassium iodide (KI) is typically used for this purpose. Iodine-125 Iodine-125 (I) is a radioisotope of iodine which has uses in biological assays, nuclear medicine imaging
Iodine-125 Iodine-125 Iodine-125 (I) is a radioisotope of iodine which has uses in biological assays, nuclear medicine imaging and in radiation therapy as brachytherapy to treat a number of conditions, including prostate cancer, uveal melanomas, and brain tumors. It is the second longest-lived radioisotope of iodine, after iodine-129. Its half-life is 59.49 days and it decays by electron capture to an excited state of tellurium-125. This state is not the metastable Te-125m, but rather a lower energy state that decays immediately by gamma decay with a maximum energy of 35 keV. Some of the excess energy of the excited Te-125 may