BCG vaccine fine powder. Sometimes the powder is sealed with vacuum in a glass ampoule. Such a glass ampoule has to be opened slowly to prevent the airflow from blowing out the powder. Then the powder has to be diluted with saline water before injecting. The history of BCG is tied to that of smallpox. Jean Antoine Villemin first recognized bovine tuberculosis in 1854 and transmitted it, and Robert Koch first distinguished "Mycobacterium bovis" from "Mycobacterium tuberculosis". Following the success of vaccination in preventing smallpox, established during the 18th century, scientists thought to find a corollary in tuberculosis by drawing a parallel
Inoculation theory motivation to maintain current attitudes and beliefs, but weak enough that the receiver will refute the counterargument (Compton, 2013; McGuire, 1964). Inoculation has been proven successful through trials and research. This article highlights vital aspects of inoculation theory, however, it is not exhaustive–there is a large volume of quality research on the theory not mentioned. Finally, while numerous studies have tested and verified the efficacy of the inoculation process, there continues to be a need for refinement and elaboration. Inoculation theory is used today as part of the suite of tools used by those engaged in shaping or manipulating public