Iodine deficiency as a side effect of administration of iodine-containing contrast agents. In some cases, excessive iodine contributes to a risk of autoimmune thyroid diseases (Hashimoto's thyroiditis and Graves' disease). Iodine deficiency resulting in goiter occurs 187 million people globally (2.7% of the population). Certain areas of the world, due to natural deficiency and unavailability of iodine, are severely affected by iodine deficiency, which affects approximately two billion people worldwide. It is particularly common in the Western Pacific, South-East Asia and Africa. Among other nations affected by iodine deficiency, China and Kazakhstan have begun taking action, while Russia has not. Successful campaigns
Iodine and iodate anions are often used for quantitative volumetric analysis, for example in iodometry and the iodine clock reaction (in which iodine also serves as a test for starch, forming a dark blue complex), and aqueous alkaline iodine solution is used in the iodoform test for methyl ketones. The iodine test for starch is still used to detect counterfeit banknotes printed on starch-containing paper. The spectra of the iodine molecule, I, consists of (not exclusively) tens of thousands of sharp spectral lines in the wavelength range 500-700 nm. It is therefore a commonly used wavelength reference (secondary standard). By measuring