BCG vaccine nesting birds and rusted electrical conduits. The resulting closure of the plant for over two years resulting in shortages of bladder cancer and tuberculosis vaccines. On October 29, 2014 Health Canada gave the permission for Sanofi to resume production of BCG. The global supply situation was analyzed in 2017 and concluded that the global supply is sufficient to meet forecasted BCG vaccine demand but risks for shortages remain mainly due to supply concentration. A weakened strain of bovine tuberculosis bacillus, "Mycobacterium bovis" is specially subcultured in a culture medium, usually Middlebrook 7H9. Some BCG vaccines are freeze dried and become
Inoculation theory strengthen their original attitudes. It uses a threat on initial beliefs to trigger a person's desire to fight against the threat, ultimately reinforcing their attitude. William McGuire set out to conduct research “on ways of inducing resistance to persuasion, under the impression that while much experimental work was being done on factors that increased persuasive effectiveness, little was being done on ways of producing resistance to persuasion” (McGuire, 1964, p. 192). McGuire was motivated to study inoculation and persuasion as a result of the aftermath of the Korean War. Nine US prisoners of war, when given the opportunity, elected to