Great Lakes is the world's largest lake located on a freshwater island. Some of these lakes even have their own islands, like Treasure Island in Lake Mindemoya in Manitoulin Island The Great Lakes also have several peninsulas between them, including the Door Peninsula, the Peninsulas of Michigan, and the Ontario Peninsula. Some of these peninsulas even contain smaller peninsulas, like the Keweenaw Peninsula, the Thumb Peninsula, the Bruce Peninsula, and the Niagara Peninsula. Population centers on the peninsulas include Grand Rapids, Michigan, Detroit, Michigan, London, Ontario, Hamilton, Ontario, and Toronto, Ontario. The Saint Lawrence Seaway and Great Lakes Waterway make the Great
Great Lakes region Hudson, Mohawk and Susquehanna form an arc of watersheds east to The Atlantic. The Great Lakes region, as distinct from the Great Lakes Basin, defines a unit of sub-national political entities defined by the U.S. states and the Canadian Province of Ontario encompassing the Great Lakes watershed, and the states and Province bordering one or more of the Great Lakes. Prior to European settlement, Iroquoian people lived around Lakes Erie and Ontario, Algonquian peoples around most of the rest, and a variety of other indigenous nation-peoples including the Lakotan, Ojibwa, Illinois, Pottawatmie, Huron, Shawnee, Erie, Fox, Miami, Crow and Ho-Chunk