BCG vaccine produce BCG. Along with supply availability from existing manufacturers, and a "new WHO prequalified vaccine" the total supply will be "sufficient to meet both suppressed 2015 demand carried over to 2016, as well as total forecast demand through 2016-2018." In the fall of 2011, the Sanofi Pasteur plant flooded causing problems with mold. The facility, located in Toronto, Ontario, Canada, produced BCG vaccine products, made with substrain Connaught, such as a tuberculosis vaccine ImmuCYST, a BCG Immunotherapeutic – a bladder cancer drug. By April 2012 the FDA had found dozens of documented problems with sterility at the plant including mold,
Inoculation theory strengthen their original attitudes. It uses a threat on initial beliefs to trigger a person's desire to fight against the threat, ultimately reinforcing their attitude. William McGuire set out to conduct research “on ways of inducing resistance to persuasion, under the impression that while much experimental work was being done on factors that increased persuasive effectiveness, little was being done on ways of producing resistance to persuasion” (McGuire, 1964, p. 192). McGuire was motivated to study inoculation and persuasion as a result of the aftermath of the Korean War. Nine US prisoners of war, when given the opportunity, elected to