BCG vaccine nesting birds and rusted electrical conduits. The resulting closure of the plant for over two years resulting in shortages of bladder cancer and tuberculosis vaccines. On October 29, 2014 Health Canada gave the permission for Sanofi to resume production of BCG. The global supply situation was analyzed in 2017 and concluded that the global supply is sufficient to meet forecasted BCG vaccine demand but risks for shortages remain mainly due to supply concentration. A weakened strain of bovine tuberculosis bacillus, "Mycobacterium bovis" is specially subcultured in a culture medium, usually Middlebrook 7H9. Some BCG vaccines are freeze dried and become
Inoculation theory counterarguments, the inoculation receiver will then seek out supporting information to further strengthen their threatened position. Finally, the held attitude or belief becomes resistant to a stronger attack, hence the medical analogy of a vaccine. Inoculation is a theory developed to strengthen existing attitudes and beliefs while building resistance to future counterarguments. For inoculation to be successful it is crucial that a threat (motivation for resistance) is imposed upon these existing ideas and refutational preemption (ability to build defenses against potential counterarguments) takes place after the inoculation. The argument that is presented through inoculation must be strong enough to initiate