W1A (TV series) cast were created by Morton as new characters. "W1A" was commissioned by Janice Hadlow, controller of BBC Two, and Shane Allen, controller of comedy commissioning. Filming began in January 2014. "W1A" was written and directed by John Morton, who previously worked on "Twenty Twelve" and "People Like Us". The producer is Paul Schlesinger and the executive producer is Jon Plowman. A second series was commissioned in September 2014, with Bonneville's return also confirmed. On 15 September 2014, it was announced that "W1A" would return for a second series in 2015. This began with a 60-minute special on 23 April, followed
Lost to follow-up are deceased. Patients who become lost to follow-up during a clinical research trial result in many negative effects on the outcome of the trial and on the pharmaceutical company sponsoring the clinical research trial. Patients who are lost-to-follow-up lead to incomplete study results, which in turn can put a bias on the result of the study as well as a bias on the investigational study medication. A lack of complete results leads to intensified FDA scrutiny of the particular study drug, as well as the pharmaceutical company sponsoring the clinical research study. Biased study outcomes also lead to issues of