Iodine-131 and/or worsen hyperthyroidism and hypothyroidism respectively, and ultimately cause temporary or even permanent thyroid conditions. It can also cause sialadenitis (an inflammation of the salivary gland), gastrointestinal disturbances, allergic reactions and rashes. Potassium iodide is also not recommended for those who have had an allergic reaction to iodine, and people with dermatitis herpetiformis and hypocomplementemic vasculitis, conditions that are linked to a risk of iodine sensitivity. The use of a particular "iodine tablet" used in portable water purification has also been determined as somewhat effective at reducing radioiodine uptake. In a small study on human subjects who, for each of
Tincture of iodine by Grossich. He claimed in 1915 that Grossich had been using a liquid akin to Liquor Iodi Fortis, and that it was he, Stretton, who had introduced the method using Tincture of Iodine BP which came to be used across the world. USP Tincture of Iodine is defined in the U.S. National Formulary (NF) as containing in each 100 mL, 1.8 to 2.2 grams of elemental iodine, and 2.1 to 2.6 grams of sodium iodide. Alcohol is 50 mL and the balance is purified water. This "2% free iodine" solution provides about one mg of free iodine per drop. USP