Povidone-iodine in people with thyroid problems. Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine. It contains from 9% to 12% available iodine. It works by releasing iodine which results in the death of a range of microorganisms. Povidone-iodine came into commercial use in 1955. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Povidone-iodine is available over the counter. The wholesale cost in the developing world is about 3.30 to 11.40 per liter of 10% solution. This amount in the United Kingdom cost the
Lugol's iodine 126.5 mg/mL. The 15% solution thus has a total iodine content of 6.32 mg per drop of 0.05 mL; the 2% solution has 0.84 mg total iodine content per drop. Potassium iodide renders the elementary iodine soluble in water through the formation of the triiodide () ion. It is not to be confused with tincture of iodine solutions, which consist of elemental iodine, and iodide salts dissolved in water and alcohol. Lugol's solution contains no alcohol. Other names for Lugol's solution are (iodine-potassium iodide); Markodine, Strong solution (Systemic); and Aqueous Iodine Solution BP. In the United Kingdom the NHS pays