Hugh Bonneville appeared in the ITV period drama "Downton Abbey", as Robert, Earl of Grantham. In early 2010, he appeared in the comedy film "Burke and Hare". In 2011 and 2012, he starred as Ian Fletcher in the award-winning BBC comedy series "Twenty Twelve", and reprised the role in the 2014 BBC comedy series "W1A". In December 2012, he appeared on BBC Two with co-star Jessica Hynes in "World's Most Dangerous Roads", travelling through Georgia. He also appeared in the much-delayed film "Hippie Hippie Shake" with Cillian Murphy and Sienna Miller. From 2011 until 2014, Bonneville was the narrator of the Channel
Median follow-up Median follow-up In statistics, median follow-up is the median time between a specified event and the time when data on outcomes are gathered. The concept is used in cancer survival analyses. Many cancer studies aim to assess the time between two events of interest, such as from treatment to remission, treatment to relapse, or diagnosis to death. This duration is generically called survival time, even if the end point is not death. Time-to-event studies must have sufficiently long follow-up durations to capture enough events to reveal meaningful patterns in the data. A short follow-up duration is appropriate for studying very