BCG vaccine nesting birds and rusted electrical conduits. The resulting closure of the plant for over two years resulting in shortages of bladder cancer and tuberculosis vaccines. On October 29, 2014 Health Canada gave the permission for Sanofi to resume production of BCG. The global supply situation was analyzed in 2017 and concluded that the global supply is sufficient to meet forecasted BCG vaccine demand but risks for shortages remain mainly due to supply concentration. A weakened strain of bovine tuberculosis bacillus, "Mycobacterium bovis" is specially subcultured in a culture medium, usually Middlebrook 7H9. Some BCG vaccines are freeze dried and become
Inoculation theory Inoculation theory Inoculation theory was developed by social psychologist William J. McGuire in 1961 to explain how attitudes and beliefs change, and more importantly, how to keep existing attitudes and beliefs consistent in the face of attempts to change them. Inoculation theory functions as a strategy to protect attitudes from change–to confer resistance to counter-attitudinal influences, whether such influences take the form of direct attacks or sustained pressures. The theory posits that weak counterarguments–arguments that are easily refuted–generate resistance within the receiver, enabling them to maintain their beliefs in the face of a future, stronger, attack. Following exposure to weak