BCG vaccine immunity against human tuberculosis. The BCG vaccine can be anywhere from 0 to 80% effective in preventing tuberculosis for a duration of 15 years; however, its protective effect appears to vary according to geography and the lab in which the vaccine strain was grown. A number of different companies make BCG, sometimes using different genetic strains of the bacterium. This may result in different product characteristics. OncoTICE, used for bladder instillation for bladder cancer, was developed by Organon Laboratories (since acquired by Schering-Plough, and in turn acquired by Merck & Co.). Pacis BCG, made from the Montréal (Institut Armand-Frappier) strain,
A2261-BCG stars, but is mysteriously diffuse, giving it a large core. On September 10, 2012, using Hubble Space Telescope's Wide Field Camera 3, scientists found out that there was no supermassive black hole present in the center. This may be the likely cause of its diffuse and large core, but it contradicts modern galactic evolutionary theories. A huge cD galaxy like A2261-BCG would be expected to have a supermassive black hole concentrated at its center. A2261-BCG A2261-BCG (short for Abell 2261 Brightest Cluster Galaxy) is a huge elliptical galaxy in the cluster Abell 2261. One of the largest galaxies known, A2261-BCG