Robert Cain (brewer) as the Robert Cain Brewery or Cains Brewery) on Stanhope Street, Liverpool in 1858. At the same time as he was developing his brewing business, Cain also made shrewd property deals and ran a hotel near to the brewery on Stanhope Street; as the company grew it expanded by buying out smaller brewers and taking control of their pubs. Cain became one of Liverpool's most successful businessmen with a passion for using the most modern techniques and equipment. He expanded the brewery several times, most notably in 1887 and in 1900–1902, when the landmark redbrick part of the brewery was
Nottingham Brewery which had become available for use once more. The original brewery had closed in 1952 after being taken over by Tennant Brothers who in turn were bought out by Whitbread. In Witbread's subsequent takeover by Interbrew the names were no longer owned by any brewing company and were adopted for the 21st century revival. The brewery was situated at 52/56 Mansfield Road, Nottingham where York House now stands.The origins of the Brewery can be traced back to at least 1847 when James Long was listed as an East India and Pale Ale Brewer on the site. He sold the business