BCG vaccine extensively used even in countries where efficacy against pulmonary tuberculosis is negligible. A number of possible reasons for the variable efficacy of BCG in different countries have been proposed. None have been proven, some have been disproved, and none can explain the lack of efficacy in both low-TB burden countries (US) and high-TB burden countries (India). The reasons for variable efficacy have been discussed at length in a WHO document on BCG. BCG has protective effects against some non-tuberculosis mycobacteria. BCG has been one of the most successful immunotherapies. BCG vaccine has been the "standard of care for patients with
Inoculation theory a Mac or a Windows-based PC computer or if one should support gay marriage. Implementing inoculation theory in studies of contemporary social issues (from mundane to controversial social issues), the variety and resurgence of studies using inoculation theory helps bolster the effectiveness and utility of the theory and provides support that it can be used to strengthen and/or predict attitudes. McGuire led a series of experiments assessing inoculation's efficacy and adding nuance to our understanding for how it works (for a review, see Compton, 2013; Compton & Pfau, 2005). Early studies (e.g., McGuire & Papageorgis, 1961) limited testing of inoculation