Povidone-iodine after treatment with radioiodine, and in patients with dermatitis herpetiformis (Duhring's disease). The sensitization rate to the product is 0.7%. The iodine in PVP-I reacts with hydrogen peroxide, silver, taurolidine and proteins such as enzymes, rendering them (and itself) ineffective. It also reacts with many mercury compounds, giving the corrosive compound mercury iodide, as well as with many metals, making it unsuitable for disinfecting metal piercings. Iodine is absorbed into the body to various degrees, depending on application area and condition of the skin. As such, it interacts with diagnostic tests of the thyroid gland such as radioiodine diagnostics, as
Tincture of iodine Lugol's iodine, by contrast, has no alcohol, and has twice the mass of potassium iodide as of elemental iodine. Alcohol content in the tincture of iodine can be determined by the methods of Alcock, Roscoe - Schorlemmer and Thurston - Thurston. As both USP solutions contain elemental iodine, which is moderately toxic when ingested in amounts larger than those required to disinfect water, tincture of iodine is sold labelled “for external use only,” and used primarily as a disinfectant. Tincture of iodine is often found in emergency survival kits, used both to disinfect wounds and to sanitize surface water for