BCG vaccine 400 per 100,000 in that higher risk context). The age of the person and the frequency with which BCG is given has always varied from country to country. BCG is prepared from a strain of the attenuated (virulence-reduced) live bovine tuberculosis bacillus, "Mycobacterium bovis", that has lost its ability to cause disease in humans. Because the living bacilli evolve to make the best use of available nutrients, they become less well-adapted to human blood and can no longer induce disease when introduced into a human host. Still, they are similar enough to their wild ancestors to provide some degree of
Inoculation theory inoculation's efficacy can be boosted with other persuasion processes, like reactance (Miller et al., 2013). Inoculation theory states that to prevent persuasion it is necessary to strengthen preexisting attitudes, beliefs, or opinions. First, the receiver must be made aware of the potential vulnerability of an existing position (e.g., attitude, belief). This establishes threat and initiates defenses to future attacks. The idea is that when a weak argument is presented in the inoculation message, processes of refutation or other means of protection will prepare for stronger arguments later. It is critical that the attack is strong enough to keep the receiver