James the Less of two, he seems to be compared to one other James. In the lists of the twelve apostles in the synoptic Gospels, there are two apostles called James, who are differentiated there by their fathers: James, son of Zebedee, and James, son of Alphaeus. Long-standing tradition identifies James, the son of Alphaeus, as James the Less. James, son of Zebedee, is then called "James the Great" (although that designation does not appear in the New Testament). Some propose that Alphaeus was the same man as Cleophas or at least the husband of Mary Clopas. In this regard, Jerome identified James
Vocation of the Apostles portrait of Diotisalvi Neroni, who had taken refuge in Rome after plotting against Piero di Cosimo de' Medici. Another exile from Constantinople is John Argyropoulos, who appears on the right. Other characters on the right are members of the Tornabuoni family. Vocation of the Apostles The Vocation of the Apostles is a fresco by the Italian Renaissance painter Domenico Ghirlandaio, executed in 1481–1482 and located in the Sistine Chapel, Rome. In 1481 a group of Florentine painters left for Rome, where they had been called as part of the reconciliation project between Lorenzo de' Medici, the "de facto" ruler of