BCG vaccine fine powder. Sometimes the powder is sealed with vacuum in a glass ampoule. Such a glass ampoule has to be opened slowly to prevent the airflow from blowing out the powder. Then the powder has to be diluted with saline water before injecting. The history of BCG is tied to that of smallpox. Jean Antoine Villemin first recognized bovine tuberculosis in 1854 and transmitted it, and Robert Koch first distinguished "Mycobacterium bovis" from "Mycobacterium tuberculosis". Following the success of vaccination in preventing smallpox, established during the 18th century, scientists thought to find a corollary in tuberculosis by drawing a parallel
Inoculation theory are more likely to be inoculated by issue/advocacy messages. They use Mobil Oil's issue/advocacy campaign to test the hypotheses. The first hypothesis was supported by the data. There was a significant effect provided by inoculation. Additionally, H1 showed that issue/advocacy inoculation messages and attack messages vary in effectiveness depending on the content. The result was also noted in the results of H2, which were also supported by the results. Finally, the results indicated that political views play a role in the effectiveness of the campaigns. Thus, confirming H3, that conservatives are easier to inoculate. They also posed a research question