Povidone-iodine is also efficient against fungi and viruses (including HIV and "Herpes simplex"). It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone-iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. There is tentative evidence that chlorhexidine and denatured alcohol used to clean skin prior to surgery is better than povidone-iodine with alcohol; however, the evidence is not strong enough as of 2015 to determine routine practice. PVP-I is contraindicated in patients with hyperthyroidism (overactive thyroid gland) and other diseases of the thyroid,
Merthiolate-Iodine-Formaldehyde Merthiolate-Iodine-Formaldehyde Merthiolate-Iodine-Formaldehyde (MIF) is a solution used in biomedical laboratories for concentration of stool samples prior to microscopic investigation for parasites. Concentration of stool is necessary in order to raise sensitivity of microscopy, as in non-concentrated samples the likelihood of finding equivalents of actually present parasites is too low. MIF enables separation of different strata of stool matter, and sedimentation of stool particles that contain parasites (usually parasite eggs). After application of MIF, usually centrifugation is used for acceleration of sedimentation. The term "Merthiolate" indicates presence of thiomersal in the solution. Due to the hazardous qualities of thiomersal, it is