BCG vaccine fine powder. Sometimes the powder is sealed with vacuum in a glass ampoule. Such a glass ampoule has to be opened slowly to prevent the airflow from blowing out the powder. Then the powder has to be diluted with saline water before injecting. The history of BCG is tied to that of smallpox. Jean Antoine Villemin first recognized bovine tuberculosis in 1854 and transmitted it, and Robert Koch first distinguished "Mycobacterium bovis" from "Mycobacterium tuberculosis". Following the success of vaccination in preventing smallpox, established during the 18th century, scientists thought to find a corollary in tuberculosis by drawing a parallel
Inoculation theory a Mac or a Windows-based PC computer or if one should support gay marriage. Implementing inoculation theory in studies of contemporary social issues (from mundane to controversial social issues), the variety and resurgence of studies using inoculation theory helps bolster the effectiveness and utility of the theory and provides support that it can be used to strengthen and/or predict attitudes. McGuire led a series of experiments assessing inoculation's efficacy and adding nuance to our understanding for how it works (for a review, see Compton, 2013; Compton & Pfau, 2005). Early studies (e.g., McGuire & Papageorgis, 1961) limited testing of inoculation