BCG vaccine nesting birds and rusted electrical conduits. The resulting closure of the plant for over two years resulting in shortages of bladder cancer and tuberculosis vaccines. On October 29, 2014 Health Canada gave the permission for Sanofi to resume production of BCG. The global supply situation was analyzed in 2017 and concluded that the global supply is sufficient to meet forecasted BCG vaccine demand but risks for shortages remain mainly due to supply concentration. A weakened strain of bovine tuberculosis bacillus, "Mycobacterium bovis" is specially subcultured in a culture medium, usually Middlebrook 7H9. Some BCG vaccines are freeze dried and become
A2261-BCG stars, but is mysteriously diffuse, giving it a large core. On September 10, 2012, using Hubble Space Telescope's Wide Field Camera 3, scientists found out that there was no supermassive black hole present in the center. This may be the likely cause of its diffuse and large core, but it contradicts modern galactic evolutionary theories. A huge cD galaxy like A2261-BCG would be expected to have a supermassive black hole concentrated at its center. A2261-BCG A2261-BCG (short for Abell 2261 Brightest Cluster Galaxy) is a huge elliptical galaxy in the cluster Abell 2261. One of the largest galaxies known, A2261-BCG