Povidone-iodine after treatment with radioiodine, and in patients with dermatitis herpetiformis (Duhring's disease). The sensitization rate to the product is 0.7%. The iodine in PVP-I reacts with hydrogen peroxide, silver, taurolidine and proteins such as enzymes, rendering them (and itself) ineffective. It also reacts with many mercury compounds, giving the corrosive compound mercury iodide, as well as with many metals, making it unsuitable for disinfecting metal piercings. Iodine is absorbed into the body to various degrees, depending on application area and condition of the skin. As such, it interacts with diagnostic tests of the thyroid gland such as radioiodine diagnostics, as
Tincture of iodine Tincture of iodine Tincture of iodine, iodine tincture, or weak iodine solution is an antiseptic. It is usually 2–7% elemental iodine, along with potassium iodide or sodium iodide, dissolved in a mixture of ethanol and water. Tincture solutions are characterized by the presence of alcohol. It was used from 1908 in pre-operative skin preparation by surgeon Antonio Grossich. In the United Kingdom the development of an iodine solution for skin sterilisation was pioneered by Lionel Stretton. The "British Medical Journal" published the detail of his work at Kidderminster Infirmary in 1909. Stretton used a much weaker solution than that used