Iodine deficiency as a side effect of administration of iodine-containing contrast agents. In some cases, excessive iodine contributes to a risk of autoimmune thyroid diseases (Hashimoto's thyroiditis and Graves' disease). Iodine deficiency resulting in goiter occurs 187 million people globally (2.7% of the population). Certain areas of the world, due to natural deficiency and unavailability of iodine, are severely affected by iodine deficiency, which affects approximately two billion people worldwide. It is particularly common in the Western Pacific, South-East Asia and Africa. Among other nations affected by iodine deficiency, China and Kazakhstan have begun taking action, while Russia has not. Successful campaigns
Iodine the iodyl cation, [IO], and is reduced by concentrated sulfuric acids to iodosyl salts involving [IO]. It may be fluorinated by fluorine, bromine trifluoride, sulfur tetrafluoride, or chloryl fluoride, resulting iodine pentafluoride, which also reacts with iodine pentoxide, giving iodine(V) oxyfluoride, IOF. A few other less stable oxides are known, notably IO and IO; their structures have not been determined, but reasonable guesses are I(IO) and [IO][IO] respectively. More important are the four oxoacids: hypoiodous acid (HIO), iodous acid (HIO), iodic acid (HIO), and periodic acid (HIO or HIO). When iodine dissolves in aqueous solution, the following reactions occur: Hypoiodous