Isotopes of iodine necessary in tests that require several days of imaging, for example, fibrinogen scan imaging to detect blood clots. Both I-123 and I-125 emit copious low energy Auger electrons after their decay, but these do not cause serious damage (double-stranded DNA breaks) in cells, unless the nuclide is incorporated into a medication that accumulates in the nucleus, or into DNA (this is never the case is clinical medicine, but it has been seen in experimental animal models). Iodine-125 is also commonly used by radiation oncologists in low dose rate brachytherapy in the treatment of cancer at sites other than the thyroid,
Isotopes of iodine Isotopes of iodine There are 37 known isotopes of iodine (I) from I to I; all undergo radioactive decay except I, which is stable. Iodine is thus a monoisotopic element. Its longest-lived radioactive isotope, I, has a half-life of 15.7 million years, which is far too short for it to exist as a primordial nuclide. Cosmogenic sources of I produce very tiny quantities of it that are too small to affect atomic weight measurements; iodine is thus also a mononuclidic element—one that is found in nature only as a single nuclide. Most I derived radioactivity on Earth is man-made, an