Iodine deficiency iodate as dough conditioner in bread and baked goods was gradually replaced by the use of other conditioning agents such as bromide. Iodine deficiency resulting in goiter occurs in 187 million people globally (2.7% of the population). It resulted in 2700 deaths in 2013 up from 2100 deaths in 1990. A low amount of thyroxine (one of the two thyroid hormones) in the blood, due to lack of dietary iodine to make it, gives rise to high levels of thyroid stimulating hormone (TSH), which stimulates the thyroid gland to increase many biochemical processes; the cellular growth and proliferation can result
Tincture of iodine Lugol's iodine, by contrast, has no alcohol, and has twice the mass of potassium iodide as of elemental iodine. Alcohol content in the tincture of iodine can be determined by the methods of Alcock, Roscoe - Schorlemmer and Thurston - Thurston. As both USP solutions contain elemental iodine, which is moderately toxic when ingested in amounts larger than those required to disinfect water, tincture of iodine is sold labelled “for external use only,” and used primarily as a disinfectant. Tincture of iodine is often found in emergency survival kits, used both to disinfect wounds and to sanitize surface water for