BCG vaccine 400 per 100,000 in that higher risk context). The age of the person and the frequency with which BCG is given has always varied from country to country. BCG is prepared from a strain of the attenuated (virulence-reduced) live bovine tuberculosis bacillus, "Mycobacterium bovis", that has lost its ability to cause disease in humans. Because the living bacilli evolve to make the best use of available nutrients, they become less well-adapted to human blood and can no longer induce disease when introduced into a human host. Still, they are similar enough to their wild ancestors to provide some degree of
Inoculation theory are many inoculation studies with the intent to inoculate children and teenagers to prevent them from smoking, doing drugs or drinking alcohol. Much of the research shows that targeting at a young age can help them resist peer pressure in high school or college. Godbold and Pfau (2000) used sixth graders from two different schools and applied inoculation theory as a defense against peer pressure to drinking alcohol. They hypothesized that a normative message, a message tailored around what the social norms are, would be more effective than an informative message. An informative message is a message tailored around giving