Povidone-iodine in people with thyroid problems. Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine. It contains from 9% to 12% available iodine. It works by releasing iodine which results in the death of a range of microorganisms. Povidone-iodine came into commercial use in 1955. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Povidone-iodine is available over the counter. The wholesale cost in the developing world is about 3.30 to 11.40 per liter of 10% solution. This amount in the United Kingdom cost the
Tincture of iodine Strong Iodine Tincture is defined in the NF as containing in each 100 mL, 6.8 to 7.5 gram of iodine, and 4.7 to 5.5 gram of potassium iodide. Purified water is 50 mL and the balance is alcohol. This 7% tincture solution is about 3.5 times more concentrated than USP 2% tincture. As in the case of Lugol's iodine, the role of iodide in the solution is to increase the solubility of the elemental iodine, by turning it to the soluble triiodide anion I. However, since iodine has moderate solubility in ethanol, it is also assisted by this solvent directly.