Holy Spirit in Christianity the Book of Acts. The Holy Spirit does not simply appear for the first time at Pentecost after the resurrection of Jesus, but is present in the Gospel of Luke (in 1–2) prior to the birth of Jesus. In , John the Baptist was said to be "filled with the Holy Spirit" prior to birth, and the Holy Spirit came upon the Virgin Mary in . In John the Baptist stated that Jesus baptized not with water but with the Holy Spirit; and the Holy Spirit descended on Jesus during his baptism in the Jordan River. In Jesus provided assurances
The Virgin and Child with St Anne and St John the Baptist holding the Child Jesus as Jesus' young cousin, St. John the Baptist, stands to the right. It currently hangs in the National Gallery in London. It was either executed in around 1499–1500, at the end of the artist's first Milanese period, or around 1506–1508, when he was shuttling between Florence and Milan. The majority of scholars prefer the latter date, although the National Gallery and others prefer the former. The subject of the cartoon is a combination of two themes popular in Florentine painting of the 15th century: "The Virgin and Child with John the Baptist" and "The Virgin and