A Shot in the Dark (1964 film) adapted from the French play "L'Idiote" by Marcel Achard. The film was released only a few months after the first Clouseau film, "The Pink Panther". Inspector Clouseau (Peter Sellers) of the Sûreté, the French national police, is called to the country home of millionaire Benjamin Ballon (George Sanders) to investigate the murder of his chauffeur, Miguel Ostos. The chauffeur was having an affair with one of the maids, Maria Gambrelli (Elke Sommer), and attacked her in her bedroom after she broke off with him. Miguel was shot and killed in her bedroom and Maria was found with the smoking gun
Lost to follow-up institutions like the FDA taken action over the recovery of or communication with patients lost-to-follow-up. Section 4.3.4 of the ICH E-6 Good Clinical Practice: Consolidated Guidance reads, "Although a subject is not obliged to give his/her reason(s) for withdrawing prematurely from a trial, the investigator should make a reasonable effort to ascertain the reason(s), while fully respecting the subject's rights." This excerpt expresses the need for physicians associated with clinical research trials to make a first-hand effort to contact patients who are lost-to-follow-up. In doing so pharmaceutical companies not only look out for the best interest of the patients who