Isotopes of iodine and non-radioactive materials can be described as "cold." There are instances in which cold iodide is administered to people in order to prevent the uptake of hot iodide by the thyroid gland. For example, blockade of thyroid iodine uptake with potassium iodide is used in nuclear medicine scintigraphy and therapy with some radioiodinated compounds that are not targeted to the thyroid, such as iobenguane (MIBG), which used to image or treat neural tissue tumors, or iodinated fibrinogen, which is used in fibrinogen scans to investigate clotting. These compounds contain iodine, but not in the iodide form. However, since they may
Isotopes of iodine iodine-135 can temporarily preclude a shut-down reactor from restarting. This is known as xenon-poisoning or "falling into an iodine pit". Iodine fission-produced isotopes not discussed above (iodine-128, iodine-130, iodine-132, and iodine-133) have a half lives of a couple of hours or minutes, rendering them almost useless in other applicable areas. Those mentioned are neutron-rich and so go through beta decay to their xenon counterparts. Iodine-128 (25 min half-life) can decay to either tellurium-128 by electron capture, or to xenon-128 by beta decay. It has a specific radioactivity of 2.177 x 10 TBq/g. Colloquially, radioactive materials can be described as "hot,"