BCG vaccine fine powder. Sometimes the powder is sealed with vacuum in a glass ampoule. Such a glass ampoule has to be opened slowly to prevent the airflow from blowing out the powder. Then the powder has to be diluted with saline water before injecting. The history of BCG is tied to that of smallpox. Jean Antoine Villemin first recognized bovine tuberculosis in 1854 and transmitted it, and Robert Koch first distinguished "Mycobacterium bovis" from "Mycobacterium tuberculosis". Following the success of vaccination in preventing smallpox, established during the 18th century, scientists thought to find a corollary in tuberculosis by drawing a parallel
Inoculation theory an individual. Future studies in the area of health can be extremely beneficial to communities. Some areas that are currently being researched can possibly help with present-day issues (e.g., inoculation-based strategies for addiction intervention to assist sober individuals from relapsing). Other areas for future studies include, promoting healthy eating habits, exercising, breastfeeding and creating positive attitude towards mammograms (Ivanov, 2017). An area that has been underdeveloped is mental health awareness. With the number of young adults and teens committing suicide due to bullying this can be an area where inoculation messages could be effective. McGuire (1961) used a medical analogy