Thousand Islands Thousand Islands-Frontenac Arch region was designated a World Biosphere Reserve by UNESCO in 2002. The Thousand Islands Bridge connects New York State and Ontario by traversing Wellesley Island at the northernmost point of Interstate 81 in Jefferson County and meets Highway 137, which leads to Highway 401. The waterfront is served by New York State Routes 12 and 37 and by the Thousand Islands Parkway in Ontario. Ontario also has the Waterfront Trail alongside the Parkway for cyclists who wish to see the area in an alternative way. Large freighters frequently ply the Saint Lawrence Seaway, but the area has
Ten Thousand Islands at the northern end of the Ten Thousand Islands was occupied year-round 3,500 years ago, and other sites are presumed to have been inundated by a rise in sea level. The material culture of the Indians living in the Ten Thousand Islands was distinctive enough to be classified as, at least, a sub-area of the Glades culture area. Almost all of the Ten Thousand Islands are currently uninhabited. The largest, Chokoloskee Island, which is connected to Everglades City by a causeway, has about 400 permanent residents. Other islands have been sporadically inhabited in the 19th and 20th centuries by individuals