Isotopes of iodine has no beta activity, is more suited for routine nuclear medicine imaging of the thyroid and other medical processes and less damaging internally to the patient. There are some situations in which iodine-124 and iodine-125 are used in medicine, also. Due to preferential uptake of iodine by the thyroid, radioiodine is extensively used in imaging of and, in the case of I-131, destroying dysfunctional thyroid tissues. Other types of tissue selectively take up certain iodine-131-containing tissue-targeting and killing radiopharmaceutical agents (such as MIBG). Iodine-125 is the only other iodine radioisotope used in radiation therapy, but only as an implanted capsule
Isotopes of iodine for the so-called iodine pit phenomenon. In addition to commercial production, I (half-life 8 days) is one of the common radioactive fission-products of nuclear fission, and is thus produced inadvertently in very large amounts inside nuclear reactors. Due to its volatility, short half-life, and high abundance in fission products, I, (along with the short-lived iodine isotope I from the longer-lived Te with a half-life of 3 days) is responsible for the largest part of radioactive contamination during the first week after accidental environmental contamination from the radioactive waste from a nuclear power plant. Radioisotopes of iodine are called radioactive iodine