Lugol's iodine a source of effectively free elemental iodine, which is readily generated from the equilibrium between elemental iodine molecules and polyiodide ions in the solution. It was historically used as a first line treatment for hyperthyroidism, as the administration of pharmacologic amounts of iodine leads to temporary inhibition of iodine organification in the thyroid gland, a phenomenon called the Wolff-Chaikoff effect. However it is not used to treat certain autoimmune causes of thyroid disease as iodine-induced blockade of iodine organification may result in hypothyroidism. They are not considered as a first line therapy because of possible induction of resistant hyperthyroidism but
Parotid gland mucosa with sphinterotomy may allow removal; however, if situated more posteriorly within the main duct, complete gland excision may be necessary. The parotid salivary gland can also be pierced and the facial nerve temporarily traumatized when an inferior alveolar local anesthesia nerve block is incorrectly administered, causing transient facial paralysis. About 80% of tumors of the parotid gland are benign. The most common of these include pleomorphic adenoma (70% of tumors, affecting predominantly females (60%)) and Warthin tumor (i.e. adenolymphoma) more in males than in females. Their importance is in relation to their anatomical position and tendency to grow over