Thyroid appearance of cells is viewed to determine whether they resemble normal or cancerous cells. There can be many nodules, which is termed a multinodular goitre, and this can sometimes be a toxic multinodular goitre. An enlarged thyroid gland is called a goitre. Goitres are present in some form in about 5% of people, and are the result of a large number of causes, including iodine deficiency, autoimmune disease (both Grave's disease and Hashimoto's thyroiditis), infection, inflammation, and infltrative disease such as sarcoidosis and amyloidosis. Sometimes no cause can be found, a state called "simple goitre". Some forms of goitre are
Without a Trace two seasons. "Without a Trace" took place within Jerry Bruckheimer's "" universe. A crossover episode featured characters Gil Grissom from "CSI" and Jack Malone from "Without a Trace" working together to solve the same case. "Without a Trace" debuted as part of the CBS fall line-up in 2002, created by Hank Steinberg and produced by Jerry Bruckheimer. It was the first show to achieve strong ratings opposite longtime NBC hit medical drama "ER"—which, like "Without a Trace", is produced by Warner Bros. Television. The first two showrunners were Steinberg and Ed Redlich. Between seasons two and three, Redlich moved away