Goitre in 1835. The German Karl Adolph von Basedow also independently reported the same constellation of symptoms in 1840, while earlier reports of the disease were also published by the Italians Giuseppe Flajani and Antonio Giuseppe Testa, in 1802 and 1810 respectively, and by the English physician Caleb Hillier Parry (a friend of Edward Jenner) in the late 18th century. Paracelsus (1493–1541) was the first person to propose a relationship between goitre and minerals (particularly lead) in drinking water. Iodine was later discovered by Bernard Courtois in 1811 from seaweed ash. Goitre was previously common in many areas that were deficient
Without a Trace two seasons. "Without a Trace" took place within Jerry Bruckheimer's "" universe. A crossover episode featured characters Gil Grissom from "CSI" and Jack Malone from "Without a Trace" working together to solve the same case. "Without a Trace" debuted as part of the CBS fall line-up in 2002, created by Hank Steinberg and produced by Jerry Bruckheimer. It was the first show to achieve strong ratings opposite longtime NBC hit medical drama "ER"—which, like "Without a Trace", is produced by Warner Bros. Television. The first two showrunners were Steinberg and Ed Redlich. Between seasons two and three, Redlich moved away