Isabel of Braganza, Duchess of Guimarães claim to the throne of Portugal. She was also part of the succession crisis. This marriage produced three children: Isabel of Braganza, Duchess of Guimarães Dona Isabel of Braganza (1514 – 16 September 1576) was a member of the House of Braganza, daughter of Jaime, Duke of Braganza (a nephew of Manuel I of Portugal) and Leonor Pérez de Guzmán. Isabel married her cousin Infante Duarte a son of Manuel I and Maria of Aragon in 1537. Isabel was dowried with the Dukedom of Guimarães, which had belonged to her brother Teodósio I, Duke of Braganza. After the marriage, Infante
House of Braganza children by his first wife, Leonor of Pérez de Guzman, and the later eight children by his second wife, Joana of Mendoça, all saw successful lives under the restored House of Braganza. Jaime I's first daughter, Isabel of Braganza, married Infante Duarte, Duke of Guimarães, and had three children, while his first son and successor, Teodósio I, was a successful prince of the Portuguese Renaissance. Five of Jaime I's children, Jaime, Maria, Fulgêncio, Teotónio, and Vicência, all entered into religious orders. The Duke's second daughter, Joana of Braganza, married Bernardino de Cardenas, 3rd Marquis of Elche, and his third daughter,