Decay chain equilibrium is achieved, each successive daughter isotope is present in direct proportion to its half-life; but since its activity is inversely proportional to its half-life, each nuclide in the decay chain finally contributes as many individual transformations as the head of the chain, though not the same energy. For example, uranium-238 is weakly radioactive, but pitchblende, a uranium ore, is 13 times more radioactive than the pure uranium metal because of the radium and other daughter isotopes it contains. Not only are unstable radium isotopes significant radioactivity emitters, but as the next stage in the decay chain they also generate
Depleted uranium Depleted uranium has been used in a number of sampling calorimeters (such as in the D0 and ZEUS detectors) due to its high density and natural radioactivity. Normal functioning of the kidney, brain, liver, heart, and numerous other systems can be affected by uranium exposure because, in addition to being weakly radioactive, uranium is a toxic metal, although less toxic than other heavy metals, such as arsenic and mercury. It is weakly radioactive but is 'persistently' so because of its long half-life. The Agency for Toxic Substances and Disease Registry states that: "to be exposed to radiation from uranium, you