Thyroid hormones which causes the thyroid to enlarge (the resulting medical condition is called "endemic colloid goitre"; see goitre). This has the effect of increasing the thyroid's ability to trap more iodide, compensating for the iodine deficiency and allowing it to produce adequate amounts of thyroid hormone. Most of the thyroid hormone circulating in the blood is bound to "transport protein"s. Only a very small fraction of the circulating hormone is free (unbound) and biologically active, hence measuring concentrations of free thyroid hormones is of great diagnostic value. When thyroid hormone is bound, it is not active, so the amount of free
Leave a Trace her feelings and finding closure, and delivering a sweet vocal that drills deep into the pleasure centres." Abby Johnston of "The Austin Chronicle" called Mayberry's performance in the song "at the level of a modern-day Cyndi Lauper." "Rolling Stone" placed "Leave a Trace" at number 24 on its list of the 50 Best Songs of 2015. "Billboard" ranked "Leave a Trace" at number fourteen on its year-end list: "On 'Leave a Trace', Iain Cook and Martin Doherty’s fine-tuned swirls of synthesizer are just begging for a killer hook, and Mayberry -- singing with more swagger than ever before -- hammers