Real Betis happened in 1928–29, with both teams winning their home matches (3–0 and 2–1). They played for the first time in the Spanish top division during the 1934–35 season, with a 0–3 home defeat for Sevilla and a 2–2 draw at Betis, with the latter winning the national championship. On 17 January 1943, Betis lost 5–0 at Sevilla, eventually being relegated. In the first game held at the Ramón Sánchez Pizjuán Stadium, on 21 September 1958, the "Verdiblancos" won it 4–2. In later years, several matches were also marred by violence, including: a security guard attacked by a Sevilla fan with
Real Betis white Kit to honor their most famous manager Paddy O'Connell, who was from Ireland. He led Betis to the division title in 1934 by a single point over Real Madrid. During the Spanish Second Republic (1931–1939), royal patronage of all organisations was nullified, and thus the club was known as Betis Balompié until after the Spanish Civil War when it would revert to the full name. The club reached the Copa del Presidente de la República final for the first time on 21 June 1931, when it lost 3–1 to Athletic Bilbao in Madrid. Betis marked their 25th anniversary year