Polonium the Curies while they were investigating the cause of pitchblende radioactivity. Pitchblende, after removal of the radioactive elements uranium and thorium, was more radioactive than the uranium and thorium combined. This spurred the Curies to search for additional radioactive elements. They first separated out polonium from pitchblende in July 1898, and five months later, also isolated radium. German scientist Willy Marckwald successfully isolated 3 milligrams of polonium in 1902, though at the time he believed it was a new element, which he dubbed "radio-tellurium", and it was not until 1905 that it was demonstrated to be the same as polonium.
Bioremediation of radioactive waste acids and siderophores that allow the dissolution and mobilization of radionuclides through the soil. It seems that siderophores on bacterial surface could also facilitate the entry of these elements within the cell as well. "Pseudomonas aeruginosa" also secretes chelating agents out that meet uranium and thorium when grown in a medium with these elements. In general, it has also been found that enterobactin siderophores are extremely effective in solubilizing actinide oxides of plutonium. Citrate is a chelator which binds to certain transition metals and radioactive actinides. Stable complexes such as bidentate, tridentate (ligands with more than one atom bound) and