Goitre related to hypermetabolism, (increased metabolism), excessive thyroid hormone, an increase in oxygen consumption, metabolic changes in protein metabolism, immunologic stimulation of diffuse goitre, and ocular changes (exophthalmos). Hypothyroid individuals may have weight gain despite poor appetite, cold intolerance, constipation and lethargy. However, these symptoms are often non-specific and make diagnosis difficult. A goitre may be classified either as nodular or diffuse. Nodular goitres are either of one nodule (uninodular) or of multiple nodules (multinodular). Worldwide, the most common cause for goitre is iodine deficiency, usually seen in countries that do not use iodized salt. Selenium deficiency is also considered a
Roberto Goitre choirs, Carlo Pavese and Mario Pigazzini, still use the Cantar Leggendo method exclusively. Goitre dedicated all his life to musical pedagogy and choral music. It was indeed he who, at the start of the 1970s, founded the magazine La Cartellina, which is still today a very important magazine on choral music and musical pedagogy. The current editor of this magazine is Marco Boschini. Roberto Goitre Roberto Goitre (Turin, 1927 - Piacenza, 1980) was an Italian choirmaster, composer and teacher. Upon finishing his academic studies, Goitre devoted himself entirely to choral conducting. At the beginning of the 1960s, on invitation from