Kingdom of France Spain and the Holy Roman Empire during the Thirty Years' War (1618–48) which had broken out in Germany. After the death of both king and cardinal, the Peace of Westphalia (1648) secured universal acceptance of Germany's political and religious fragmentation, but the Regency of Anne of Austria and her minister Cardinal Mazarin experienced a civil uprising known as the Fronde (1648–1653) which expanded into a Franco-Spanish War (1653–59). The Treaty of the Pyrenees (1659) formalised France's seizure (1642) of the Spanish territory of Roussillon after the crushing of the ephemeral Catalan Republic and ushered a short period of peace. The
Portuguese Restoration War at the negotiations for the European settlement-of-settlements, the new "realpolitik" of the peace of Westphalia (1648). With this treaty and the end of hostilities in Catalonia in 1652, Spain was again ready to direct its efforts against Portugal, but it faced a lack of men, resources, and, especially, good military commanders. By 1662, Spain had committed itself to a major effort to end the war. John of Austria the Younger, Philip IV's illegitimate son, led 14,000 men into Alentejo, and, the following year, they succeeded in taking Évora, the major city of the region. The Portuguese, under António Luís de