Uranium ore for silver in the 16th century. F.E. Brückmann made the first mineralogical description of the mineral in 1727 and the vein deposit Jachymov in the Czech Republic became the type locality for uraninite. In 1789 the German chemist M. H. Klaproth discovered the element of uranium in a sample of pitchblende from the Johanngeorgenstadt vein deposit. The first industrial production of uranium was made from the Jachymov deposit and Marie and Pierre Curie used the tailings of the mine for their discovery of polonium and radium. Vein deposits consist of uranium minerals filling in cavities such as cracks, veins, fractures,
Uranium especially when inhaled by way of dust into the lungs, pose a more serious exposure hazard. After entering the bloodstream, the absorbed uranium tends to bioaccumulate and stay for many years in bone tissue because of uranium's affinity for phosphates. Uranium is not absorbed through the skin, and alpha particles released by uranium cannot penetrate the skin. Incorporated uranium becomes uranyl ions, which accumulate in bone, liver, kidney, and reproductive tissues. Uranium can be decontaminated from steel surfaces and aquifers. Normal functioning of the kidney, brain, liver, heart, and other systems can be affected by uranium exposure, because, besides being