Congenital iodine deficiency syndrome Congenital iodine deficiency syndrome Congenital iodine deficiency syndrome, previously known as cretinism, is a condition of severely stunted physical and mental growth owing to untreated congenital deficiency of thyroid hormone (congenital hypothyroidism) usually owing to maternal hypothyroidism. Around the world, the most common cause of congenital hypothyroidism is iodine deficiency. It has affected many people worldwide and continues to be a major public health problem in many countries. Iodine is an essential trace element, necessary primarily for the synthesis of thyroid hormones. Iodine deficiency is the most common preventable cause of brain damage worldwide. Although iodine is found in many
Without a Trace two seasons. "Without a Trace" took place within Jerry Bruckheimer's "" universe. A crossover episode featured characters Gil Grissom from "CSI" and Jack Malone from "Without a Trace" working together to solve the same case. "Without a Trace" debuted as part of the CBS fall line-up in 2002, created by Hank Steinberg and produced by Jerry Bruckheimer. It was the first show to achieve strong ratings opposite longtime NBC hit medical drama "ER"—which, like "Without a Trace", is produced by Warner Bros. Television. The first two showrunners were Steinberg and Ed Redlich. Between seasons two and three, Redlich moved away