Karachay horse due place being mentioned in the State stud books and official lists of species of the USSR and Russia in the 1990s. In 1998 a group of Karachay-Cherkessiya`s horsemen with three Karachay horses ascended the east top of the mountain Elbrus, making an unprecedented act. In 1999 the horsemen ascended west top of the highest mountain in Europe. The Karachay horses' is thus strong with strong and adapted limbs to climbing mountains. Special credit goes to an expert on horse breeding named Klych Geriy Urusov who was the mastermind of Elbrus conquest on horseback. At the present time Karachay horse
MT-ATP6 to cause mtDNA-associated Leigh syndrome involve MT-TL1, MT-TK, MT-TW, MT-TV, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND5, MT-ND6 and MT-CO3. Abnormalities in mitochondrial energy generation result in neurodegenerative disorders like Leigh syndrome, which is characterized by an onset of symptoms between 12 months and three years of age. The symptoms frequently present themselves following a viral infection and include movement disorders and peripheral neuropathy, as well as hypotonia, spasticity and cerebellar ataxia. Roughly half of affected patients die of respiratory or cardiac failure by the age of three. Leigh syndrome is a maternally inherited disorder and its diagnosis is established through genetic