Congenital iodine deficiency syndrome Congenital iodine deficiency syndrome Congenital iodine deficiency syndrome, previously known as cretinism, is a condition of severely stunted physical and mental growth owing to untreated congenital deficiency of thyroid hormone (congenital hypothyroidism) usually owing to maternal hypothyroidism. Around the world, the most common cause of congenital hypothyroidism is iodine deficiency. It has affected many people worldwide and continues to be a major public health problem in many countries. Iodine is an essential trace element, necessary primarily for the synthesis of thyroid hormones. Iodine deficiency is the most common preventable cause of brain damage worldwide. Although iodine is found in many
Trace metal vegetables are sources. Taken in excessive amounts, trace elements can cause problems. For example fluorine is required for the formation of bones and enamel on teeth. However, when taken in an excessive amount can cause a disease called "Fluorosis', in which bone deformations and yellowing of teeth are seen. Fluorine can occur naturally in some areas in ground water. Trace metals include iron that can help to prevent anemia, and zinc that is a cofactor in over 100 enzyme reactions. Trace metal Trace metals are the metals subset of trace elements; that is, metals normally present in small but measurable