Uranium mining Cornwall. The first deliberate mining of radioactive ores took place in Jáchymov, a silver-mining city in the Czech Republic. Marie Curie used pitchblende ore from Jáchymov to isolate the element radium, a decay product of uranium. Until World War II uranium was mined primarily for its radium content; some carnotite deposits were mined primarily for the vanadium content. Sources for radium, contained in the uranium ore, were sought for use as luminous paint for watch dials and other instruments, as well as for health-related applications, some of which in retrospect were certainly harmful. The byproduct uranium was used mostly as
Uranium weakly radioactive, uranium is a toxic metal. Uranium is also a reproductive toxicant. Radiological effects are generally local because alpha radiation, the primary form of U decay, has a very short range, and will not penetrate skin. Alpha radiation from inhaled uranium has been demonstrated to cause lung cancer in exposed nuclear workers. Uranyl () ions, such as from uranium trioxide or uranyl nitrate and other hexavalent uranium compounds, have been shown to cause birth defects and immune system damage in laboratory animals. While the CDC has published one study that no human cancer has been seen as a result