Uranium ore for silver in the 16th century. F.E. Brückmann made the first mineralogical description of the mineral in 1727 and the vein deposit Jachymov in the Czech Republic became the type locality for uraninite. In 1789 the German chemist M. H. Klaproth discovered the element of uranium in a sample of pitchblende from the Johanngeorgenstadt vein deposit. The first industrial production of uranium was made from the Jachymov deposit and Marie and Pierre Curie used the tailings of the mine for their discovery of polonium and radium. Vein deposits consist of uranium minerals filling in cavities such as cracks, veins, fractures,
Uranium trioxide which operates at the world's largest uranium refinery at Blind River, Ontario, produces high-purity uranium trioxide. It has been reported that the corrosion of uranium in a silica rich aqueous solution forms uranium dioxide, uranium trioxide, and coffinite. In pure water, schoepite (UO)O(OH)·12(HO) is formed in the first week and then after four months studtite (UO)O·4(HO) was produced. This alteration of uranium oxide also leads to the formation of metastudtite, Like all hexavalent uranium compounds, UO is hazardous by inhalation, ingestion, and through skin contact. It is a poisonous, slightly radioactive substance, which may cause shortness of breath, coughing, acute