Mohammed bin Abdulla Al Thani at an altitude of 6,962 m. On 28 August 2012, he climbed Mt. Elbrus the tallest peak in Europe at an altitude of 5,642m in Russia. Al Thani has climbed Mount Kilimanjaro in Tanzania at an altitude of 5,963m twice, on 25 February 2010 and 12 November 2011, respectively. On 25 December 2012, he climbed Vinson Massif, the highest mountain in Antarctica at an altitude of 4,897 m. On 11 October 2012, he summited Mt. Kosciuszko in Australia at an altitude of 2,228 m. Al Thani has also climbed Mont Blanc on 10 September 2011 at an altitude of 4810
MT-ND4L are transferred through a series of iron-sulfur (Fe-S) clusters in the prosthetic arm and finally to coenzyme Q10 (CoQ), which is reduced to ubiquinol (CoQH). The flow of electrons changes the redox state of the protein, resulting in a conformational change and p"K" shift of the ionizable side chain, which pumps four hydrogen ions out of the mitochondrial matrix. Mitochondrial dysfunction resulting from variants of MT-ND4L, MT-ND1 and MT-ND2 have been linked to BMI in adults and implicated in metabolic disorders including obesity, diabetes and hypertension. A T>C mutation at position 10,663 in the mitochondrial gene MT-ND4L is known to