Goitre related to hypermetabolism, (increased metabolism), excessive thyroid hormone, an increase in oxygen consumption, metabolic changes in protein metabolism, immunologic stimulation of diffuse goitre, and ocular changes (exophthalmos). Hypothyroid individuals may have weight gain despite poor appetite, cold intolerance, constipation and lethargy. However, these symptoms are often non-specific and make diagnosis difficult. A goitre may be classified either as nodular or diffuse. Nodular goitres are either of one nodule (uninodular) or of multiple nodules (multinodular). Worldwide, the most common cause for goitre is iodine deficiency, usually seen in countries that do not use iodized salt. Selenium deficiency is also considered a
Leave a Trace Leave a Trace "Leave a Trace" is a song by Scottish synth-pop band Chvrches from their second studio album "Every Open Eye". It was released as the band's first official single on 17 July 2015 via Virgin and Goodbye Records. During an interview with "Pitchfork", Lauren Mayberry said of the song: "Leave a Trace" was streamed on the band's official SoundCloud page. The song received generally positive reviews. Luke Winstanley of "Clash" called the song "another highlight, outrageously infectious and immediate, all centred around a gentle but persistent bass pulse." Sam Shepherd of "musicOMH" felt it "finds Mayberry certain of