Toxic multinodular goitre Toxic multinodular goitre Toxic multinodular goiter (also known as toxic nodular goiter, or Plummer's disease) is an active multinodular goiter associated with hyperthyroidism. It is a common cause of hyperthyroidism in which there is excess production of thyroid hormones from functionally autonomous thyroid nodules, which do not require stimulation from thyroid stimulating hormone (TSH). Toxic multinodular goiter is the second most common cause of hyperthyroidism (after Graves' disease) in the developed world, whereas iodine deficiency is the most common cause of hypothyroidism in developing-world countries where the population is iodine-deficient. (Decreased iodine leads to decreased thyroid hormone.) However, iodine deficiency
Leave a Trace Leave a Trace "Leave a Trace" is a song by Scottish synth-pop band Chvrches from their second studio album "Every Open Eye". It was released as the band's first official single on 17 July 2015 via Virgin and Goodbye Records. During an interview with "Pitchfork", Lauren Mayberry said of the song: "Leave a Trace" was streamed on the band's official SoundCloud page. The song received generally positive reviews. Luke Winstanley of "Clash" called the song "another highlight, outrageously infectious and immediate, all centred around a gentle but persistent bass pulse." Sam Shepherd of "musicOMH" felt it "finds Mayberry certain of