Real Betis happened in 1928–29, with both teams winning their home matches (3–0 and 2–1). They played for the first time in the Spanish top division during the 1934–35 season, with a 0–3 home defeat for Sevilla and a 2–2 draw at Betis, with the latter winning the national championship. On 17 January 1943, Betis lost 5–0 at Sevilla, eventually being relegated. In the first game held at the Ramón Sánchez Pizjuán Stadium, on 21 September 1958, the "Verdiblancos" won it 4–2. In later years, several matches were also marred by violence, including: a security guard attacked by a Sevilla fan with
2015–16 Real Madrid C.F. season thrashed Real Betis in their home opener by a score of 5–0 after braces from Gareth Bale and James Rodríguez and a goal from Karim Benzema. Cristiano Ronaldo scored five goals and had an assist for Benzema in a 6–0 away win at Espanyol. With the five goals, Ronaldo set his Spanish league goal tally to 230 goals in 203 games, surpassing Raúl's record of 228 goals in 550 games for Real Madrid in La Liga, becoming the all-time top scorer for Real Madrid in the Spanish league. Real started the 2015–16 UEFA Champions League season with a 4–0 victory