Thyroid hormones which causes the thyroid to enlarge (the resulting medical condition is called "endemic colloid goitre"; see goitre). This has the effect of increasing the thyroid's ability to trap more iodide, compensating for the iodine deficiency and allowing it to produce adequate amounts of thyroid hormone. Most of the thyroid hormone circulating in the blood is bound to "transport protein"s. Only a very small fraction of the circulating hormone is free (unbound) and biologically active, hence measuring concentrations of free thyroid hormones is of great diagnostic value. When thyroid hormone is bound, it is not active, so the amount of free
Roberto Goitre Roberto Goitre Roberto Goitre (Turin, 1927 - Piacenza, 1980) was an Italian choirmaster, composer and teacher. Upon finishing his academic studies, Goitre devoted himself entirely to choral conducting. At the beginning of the 1960s, on invitation from Marcello Abbado, he became director of the choir of the "Giuseppe Nicolini" Conservatoire in Piacenza, where he taught until his death in 1980. In the 1970s Goitre turned his attention to the musical pedagogy of Zoltán Kodály and spent a significant amount of time in Hungary carrying out research. He also widened his knowledge of Italian and Hungarian folk tunes, which he made