Goitre related to hypermetabolism, (increased metabolism), excessive thyroid hormone, an increase in oxygen consumption, metabolic changes in protein metabolism, immunologic stimulation of diffuse goitre, and ocular changes (exophthalmos). Hypothyroid individuals may have weight gain despite poor appetite, cold intolerance, constipation and lethargy. However, these symptoms are often non-specific and make diagnosis difficult. A goitre may be classified either as nodular or diffuse. Nodular goitres are either of one nodule (uninodular) or of multiple nodules (multinodular). Worldwide, the most common cause for goitre is iodine deficiency, usually seen in countries that do not use iodized salt. Selenium deficiency is also considered a
Pseudo-goitre attached to the thyroid such as a true goitre, also moves along with thyroid. A pseudogoitre is unlikely if the area of fullness moves with swallowing. If pseudogoitre is due to cervical lordosis, the fullness disappears on straightening of the neck. A high-lying thyroid can be excluded by palpation. If the diagnosis is uncertain after clinical examination, an ultrasonogram is taken to rule out pathology of the neck. Pseudo-goitre Pseudo-goitre is the apparent fullness of the front part of the neck. It may be mistakenly diagnosed as thyroid enlargement. The cause for pseudogoitre can be fat tissue of the neck,