Isabel of Braganza, Duchess of Guimarães claim to the throne of Portugal. She was also part of the succession crisis. This marriage produced three children: Isabel of Braganza, Duchess of Guimarães Dona Isabel of Braganza (1514 – 16 September 1576) was a member of the House of Braganza, daughter of Jaime, Duke of Braganza (a nephew of Manuel I of Portugal) and Leonor Pérez de Guzmán. Isabel married her cousin Infante Duarte a son of Manuel I and Maria of Aragon in 1537. Isabel was dowried with the Dukedom of Guimarães, which had belonged to her brother Teodósio I, Duke of Braganza. After the marriage, Infante
House of Braganza of Marquis of Vila Viçosa and Count of Neiva. Fernando I's children, by his wife, Joana de Castro, Lady of Cadaval, continued to enlarge the influence of the House of Braganza. Of his nine children, all six who survived to adulthood established themselves either through positions or marriages, though the actions of King João II would seek to weaken their influence. Fernando I's first son and successor, Fernando II, was initially a bright and popular nobleman, but his conflict with King João II would see his and the House's downfall. His second son, João of Braganza, 1st Marquis of Montemor-o-Novo,