Samina Baig on 3 July 2014 in Alaska, where they pushed to capture the highest mountain in Europe, Mount Elbrus, which is 5,642 meters tall. At 9 am on 24 July 2014, Samina Baig stood at the top of Mt Elbrus, the highest peak in Russia, with her brother, holding the Pakistani flag high for a picture. With this summit, the 23 years old climber completed the challenge of climbing seven of the highest mountains around the world, including Mount Everest which she conquered in May, 2013. Carstensz Pyramid (March 2014); In March, Samina Baig and Mirza Ali reached the top of
MT-ND4L are transferred through a series of iron-sulfur (Fe-S) clusters in the prosthetic arm and finally to coenzyme Q10 (CoQ), which is reduced to ubiquinol (CoQH). The flow of electrons changes the redox state of the protein, resulting in a conformational change and p"K" shift of the ionizable side chain, which pumps four hydrogen ions out of the mitochondrial matrix. Mitochondrial dysfunction resulting from variants of MT-ND4L, MT-ND1 and MT-ND2 have been linked to BMI in adults and implicated in metabolic disorders including obesity, diabetes and hypertension. A T>C mutation at position 10,663 in the mitochondrial gene MT-ND4L is known to