Kingdom of France Spain and the Holy Roman Empire during the Thirty Years' War (1618–48) which had broken out in Germany. After the death of both king and cardinal, the Peace of Westphalia (1648) secured universal acceptance of Germany's political and religious fragmentation, but the Regency of Anne of Austria and her minister Cardinal Mazarin experienced a civil uprising known as the Fronde (1648–1653) which expanded into a Franco-Spanish War (1653–59). The Treaty of the Pyrenees (1659) formalised France's seizure (1642) of the Spanish territory of Roussillon after the crushing of the ephemeral Catalan Republic and ushered a short period of peace. The
War of the Fifth Coalition not been able to save Prussia. The Russian and French armies met in February 1807 at the savage and indecisive Battle of Eylau, which left behind between 30,000–50,000 casualties. Napoleon regrouped his forces after the battle and continued to pursue the Russians in upcoming months. The action in Poland finally culminated on 14 June 1807, when the French mauled their Russian opponents at the Battle of Friedland. The resulting Treaty of Tilsit in July ended two years of bloodshed and left France as the dominant power on the European continent. It also severely weakened Prussia and formed a Franco-Russian axis