Iodine deficiency French, the term "crétin des Alpes" also became current, since the condition was observed in remote valleys of the Alps in particular. The word "cretin" appeared in English in 1779. While reporting recent progress towards overcoming iodine-deficiency disorders worldwide, "The Lancet" noted: "According to World Health Organization, in 2007, nearly 2 billion individuals had insufficient iodine intake, a third being of school age." A conclusion was made that the single most preventable cause of intellectual disability is that of iodine deficiency. There is preliminary evidence that iodine deficiency enhances the sensitivity of breast tissue to estrogen. In rats treated with
The Trace (Land Between the Lakes) The Trace (Land Between the Lakes) The Woodlands Trace National Scenic Byway, also known as "The Trace," is the major north–south roadway that traverses the Land Between the Lakes National Recreation Area in two counties in western Kentucky and northwestern Stewart County in northwest Middle Tennessee. It is estimated to be in length. The road is part of the National Scenic Byway system. Although it is not signed, it is listed on LBL's road logs as FD-100. The road is called "The Trace", which is what many roads and paths were called in pioneer times. "Trace" is short for "Buffalo