Polonium the Curies while they were investigating the cause of pitchblende radioactivity. Pitchblende, after removal of the radioactive elements uranium and thorium, was more radioactive than the uranium and thorium combined. This spurred the Curies to search for additional radioactive elements. They first separated out polonium from pitchblende in July 1898, and five months later, also isolated radium. German scientist Willy Marckwald successfully isolated 3 milligrams of polonium in 1902, though at the time he believed it was a new element, which he dubbed "radio-tellurium", and it was not until 1905 that it was demonstrated to be the same as polonium.
Uranium mining in Colorado to about 1916. The uranium boom of the late 1940s revived the search for uranium orebodies in the gold and silver mines of the Front Range. Again, uranium was produced from a number of mines, but the orebodies were small and discontinuous. Pitchblende was discovered in 1948 in the Caribou silver mine at the town of Caribou, Boulder County. A small amount of uranium ore was produced. In 1949 janitor and weekend prospector Fred Schwartzwalder discovered uranium at an abandoned copper prospect in Jefferson County about ten miles northeast of Central City and eight miles north of Golden. The deposit