Kingdom of France Spain and the Holy Roman Empire during the Thirty Years' War (1618–48) which had broken out in Germany. After the death of both king and cardinal, the Peace of Westphalia (1648) secured universal acceptance of Germany's political and religious fragmentation, but the Regency of Anne of Austria and her minister Cardinal Mazarin experienced a civil uprising known as the Fronde (1648–1653) which expanded into a Franco-Spanish War (1653–59). The Treaty of the Pyrenees (1659) formalised France's seizure (1642) of the Spanish territory of Roussillon after the crushing of the ephemeral Catalan Republic and ushered a short period of peace. The
Siege of Breda (1624) thereafter. The siege of 1624 captured the attention of European princes and, along with other battles like White Mountain (1620), played a part in the Spanish army regaining the formidable reputation it had held throughout the previous century. In the latter stages of the combined Eighty and Thirty Years' wars that had greatly strained Spanish resources, Breda was lost to the Dutch under Frederick Henry after a four-month siege. In the 1648 Treaty of Westphalia that ended the Thirty and Eighty Years' wars, it was ceded to the Dutch Republic. There were several motives for Spinola's siege of Breda. Because