Didsbury is also likely that Bonnie Prince Charlie crossed the Mersey at Didsbury in 1745, in the Jacobite march south from Manchester to Derby, and again in his subsequent retreat. Jewish immigrants started to arrive in Manchester from the late 18th century, initially settling mainly in the suburbs to the north of the city. From the 1890s onwards, many of them moved to what were seen as the more "sophisticated" suburbs in the south, such as Withington and Didsbury. The influx of Jewish immigrants led to West Didsbury being nicknamed "Yidsbury" and Palatine Road, a main road through West Didsbury, "Palestine
Didsbury, Alberta group who came west in 1894. 1897 saw the arrival of the Canadian Pacific Railway, which pushed forward the town's development. The CPR constructed a station in the town in 1904. Didsbury was incorporated as a village in 1905 and as a town on September 6, 1906. Fires in 1914 and 1924 destroyed the early "boomtown" commercial streetscape and led to the passing by Town Council of a bylaw which required masonry construction for all new downtown commercial buildings. Many of these brick buildings stand today. In the 2016 Census of Population conducted by Statistics Canada, the Town of Didsbury