Upstate New York treaties drawn up after the war ceded much of the land to settlers of European descent. It is largely rural with rugged terrain. The development of Upstate New York was spurred by the opening of the Erie Canal in 1825, which greatly eased the transport of goods between the port of New York City and inland cities along the Great Lakes. As a result, Upstate became a hotbed for manufacturing, giving birth to such firms as General Electric, IBM, Kodak, and Xerox, and it welcomed a large influx of immigrants. Since the mid 20th century, American de-industrialization has contributed to
Great Lakes Greyhound Lines new subsidiary, named as the Great Lakes Greyhound Lines, which in 1941 took over the EMM. In 1941, when the Great Lakes GL came into existence, The Greyhound Corporation merged the Ohio GL into the new Great Lakes GL. The Ohio GL had run between Detroit and Louisville (in Kentucky) via Toledo, Dayton, and Cincinnati (all three in Ohio), plus along a detached route between Evansville and Indianapolis (both in Indiana). [The route segment between Louisville and Cincinnati had come from the Southland Transportation Company, which Harris Spearin, with the backing and financing of Wickman in Minnesota, had founded in