Congenital iodine deficiency syndrome degree of iodine deficiency was milder and manifested primarily as thyroid enlargement rather than severe mental and physical impairment. In Switzerland, for example, where soil does not contain a large amount of iodine, cases of congenital iodine deficiency syndrome were very abundant and even considered genetically caused. As the variety of food sources dramatically increased in Europe and North America and the populations became less completely dependent on locally grown food, the prevalence of endemic goitre diminished. The early 20th century saw the discovery of the relationships of neurological impairment with hypothyroidism due to iodine deficiency. Both have been largely
The Trace (Land Between the Lakes) The Trace (Land Between the Lakes) The Woodlands Trace National Scenic Byway, also known as "The Trace," is the major north–south roadway that traverses the Land Between the Lakes National Recreation Area in two counties in western Kentucky and northwestern Stewart County in northwest Middle Tennessee. It is estimated to be in length. The road is part of the National Scenic Byway system. Although it is not signed, it is listed on LBL's road logs as FD-100. The road is called "The Trace", which is what many roads and paths were called in pioneer times. "Trace" is short for "Buffalo