Real Betis happened in 1928–29, with both teams winning their home matches (3–0 and 2–1). They played for the first time in the Spanish top division during the 1934–35 season, with a 0–3 home defeat for Sevilla and a 2–2 draw at Betis, with the latter winning the national championship. On 17 January 1943, Betis lost 5–0 at Sevilla, eventually being relegated. In the first game held at the Ramón Sánchez Pizjuán Stadium, on 21 September 1958, the "Verdiblancos" won it 4–2. In later years, several matches were also marred by violence, including: a security guard attacked by a Sevilla fan with
Real Betis time after an extra-time winner by youth graduate Dani in a 2–1 win against Osasuna. The league finish meant Betis became the first Andalucian team to compete in the UEFA Champions League, and it reached the group stage after disposing of Monaco in the last qualifying round (3–2 on aggregate). Drawn in Group G, and in spite of a 1–0 home win against Chelsea, the club eventually finished third, being "demoted" to the UEFA Cup, where it would be ousted in the round of 16 by defeated Steaua București (0–0 away draw, 0–3 home loss). Betis celebrated their centenary year