Seavey's Island side of Seavey's Island at the former site of Camp Long, a stockade named for Secretary of the Navy John Long, where 1,612 prisoners of war from the Battle of Santiago de Cuba were confined from July 11 to mid-September 1898 during the Spanish–American War. Camp Heywood, a Marine camp named after Colonel Charles Heywood, was located just north of the naval prison. It was occupied after the 1st Battalion's return from Cuba in late August until September 21, 1898. According to the National Trust for Historic Preservation, the Portsmouth Naval Shipyard has 62 buildings listed on the National Register
Santiago de Cuba (baseball) between the two cities (La Habana and Santiago de Cuba) dating back to the era when Cuba was a colony of Spain two centuries ago. The Super Classic of the Cuban National Series between Santiago de Cuba and Industriales takes place six times per season. The "Avispas" (Wasps) won three straight titles during the seasons ending in 1999, 2000, and 2001. The club also won the title during the season ending in 2008. Santiago de Cuba sent only one player to the 2006 World Baseball Classic, pitcher Ormari Romero. But to the 2009 World Baseball Classic Santiago de Cuba sent