Jáchymov 227 zentners [11.35 tonnes] were produced), nickel, bismuth and uranium ore were also extracted. There were also other industries: an enormous tobacco factory employed 1,000 women. In addition, there was the manufacture of gloves and corks and of bobbin lace. On 31 March 1873 the town almost entirely burnt down. At the end of the 19th century, Marie Curie discovered, in tons of pitchblende ore containing uraninite from Joachimsthal, the element radium, for which she won the Nobel Prize in Chemistry. Until the First World War this was the foremost source of radium in the world. The first radon spa
Uranium especially when inhaled by way of dust into the lungs, pose a more serious exposure hazard. After entering the bloodstream, the absorbed uranium tends to bioaccumulate and stay for many years in bone tissue because of uranium's affinity for phosphates. Uranium is not absorbed through the skin, and alpha particles released by uranium cannot penetrate the skin. Incorporated uranium becomes uranyl ions, which accumulate in bone, liver, kidney, and reproductive tissues. Uranium can be decontaminated from steel surfaces and aquifers. Normal functioning of the kidney, brain, liver, heart, and other systems can be affected by uranium exposure, because, besides being