Goitre in 1835. The German Karl Adolph von Basedow also independently reported the same constellation of symptoms in 1840, while earlier reports of the disease were also published by the Italians Giuseppe Flajani and Antonio Giuseppe Testa, in 1802 and 1810 respectively, and by the English physician Caleb Hillier Parry (a friend of Edward Jenner) in the late 18th century. Paracelsus (1493–1541) was the first person to propose a relationship between goitre and minerals (particularly lead) in drinking water. Iodine was later discovered by Bernard Courtois in 1811 from seaweed ash. Goitre was previously common in many areas that were deficient
Without a Trace (film) confusion with the 1982 film "Missing". The film was released in North America on February 4, 1983, and grossed $9.6 million. Janet Maslin of "The New York Times" called it "a reasonably well-made film" on its own terms but said it "deserves more thoughtful and imaginative treatment". Without a Trace (film) Without a Trace is a 1983 American drama film. It is based on the novel "Still Missing" by Beth Gutcheon. The film stars Kate Nelligan, Judd Hirsch, David Dukes and Stockard Channing. The story is partly based on the disappearance of Etan Patz. Susan Selky is a well-known English