Elbrus-2S+ In December 2014, an implementation of the OpenGL 3.3 standard was demonstrated by running the game "Doom 3" BFG Edition on an Elbrus-4S, clocked at 720 MHz, using a Radeon graphics card with 2 gigabytes of video memory. In April 2015, MCST announced two new products based on the Elbrus-4S CPU: One 19-inch rack server with four CPUs (16 cores) and one personal computer. In December 2015, the first shipment of PCs based on VLIW CPU Elbrus-4s was made in Russia. Elbrus-2S+ Elbrus-2S+ () is a multi-core microprocessor based on the Elbrus 2000 architecture developed by Moscow Center of SPARC
MT-ATP6 to cause mtDNA-associated Leigh syndrome involve MT-TL1, MT-TK, MT-TW, MT-TV, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND5, MT-ND6 and MT-CO3. Abnormalities in mitochondrial energy generation result in neurodegenerative disorders like Leigh syndrome, which is characterized by an onset of symptoms between 12 months and three years of age. The symptoms frequently present themselves following a viral infection and include movement disorders and peripheral neuropathy, as well as hypotonia, spasticity and cerebellar ataxia. Roughly half of affected patients die of respiratory or cardiac failure by the age of three. Leigh syndrome is a maternally inherited disorder and its diagnosis is established through genetic