Prielbrusye National Park Prielbrusye National Park Prielbrusye National Park () (also, Prielbrus'e, in English, "Mt. Elbrus") is centered on Mt. Elbrus, the highest mountain in Europe at 5,632 meters above sea level. The relative isolation of steep gorges has led to high levels of endemism and biodiversity. The park is in the central Caucasus Mountains, one of 22 national parks in the Caucasus of different nationalities, covering 1.8% of the region. The park is situated in Elbrussky District and Zolsky District, in the southwestern corner of the Kabardino-Balkar Republic of Russia. Prielbrusye National Park is located on the peaks and north slope of
MT-ND4L are transferred through a series of iron-sulfur (Fe-S) clusters in the prosthetic arm and finally to coenzyme Q10 (CoQ), which is reduced to ubiquinol (CoQH). The flow of electrons changes the redox state of the protein, resulting in a conformational change and p"K" shift of the ionizable side chain, which pumps four hydrogen ions out of the mitochondrial matrix. Mitochondrial dysfunction resulting from variants of MT-ND4L, MT-ND1 and MT-ND2 have been linked to BMI in adults and implicated in metabolic disorders including obesity, diabetes and hypertension. A T>C mutation at position 10,663 in the mitochondrial gene MT-ND4L is known to