House of Braganza great difficulty under the reign of King João II. By the tenure of the third duke, Fernando II, the House of Braganza was undoubtedly one of the greatest noble houses of Portugal and Iberia as a whole. Fernando II continued the House's legacy of acquisition and gained the title of Duke of Guimarães. To the Duke and the House's downfall, however, King João II's reign concerned itself with the royal consolidation of power and the diminishment of the nobility. In his mission to centralize power, the King executed many nobleman of the great houses of Portugal, alongside confiscating their properties
House of Braganza children by his first wife, Leonor of Pérez de Guzman, and the later eight children by his second wife, Joana of Mendoça, all saw successful lives under the restored House of Braganza. Jaime I's first daughter, Isabel of Braganza, married Infante Duarte, Duke of Guimarães, and had three children, while his first son and successor, Teodósio I, was a successful prince of the Portuguese Renaissance. Five of Jaime I's children, Jaime, Maria, Fulgêncio, Teotónio, and Vicência, all entered into religious orders. The Duke's second daughter, Joana of Braganza, married Bernardino de Cardenas, 3rd Marquis of Elche, and his third daughter,