History of Cuba U.S. embassy in Havana was formally reopened in August 2015. History of Cuba The island of Cuba was inhabited by various Mesoamerican cultures prior to the arrival of the Spanish explorer Christopher Columbus in 1492. After Columbus' arrival, Spain conquered Cuba and appointed Spanish governors to rule in Havana. In 1762, Havana was briefly occupied by Great Britain, before being returned to Spain in exchange for Florida. A series of rebellions during the 19th century failed to end the Spanish rule. However, the Spanish–American War resulted in a Spanish withdrawal from the island in 1898, and following three-and-a-half years of
Santiago de Cuba Santiago de Cuba Santiago de Cuba is the second-largest city of Cuba and the capital city of Santiago de Cuba Province. It lies in the southeastern area of the island, some southeast of the Cuban capital of Havana. The municipality extends over , and contains the communities of Antonio Maceo, Bravo, Castillo Duany, Daiquirí, El Caney, El Cobre, El Cristo, Guilera, Leyte Vidal, Moncada and Siboney. Historically Santiago de Cuba has long been the second-most important city on the island after Havana, and still remains the second-largest. It is on a bay connected to the Caribbean Sea and is an