Uranium in the environment resulting in workers exposed to high levels of radiation. Conventional uranium ore treatment mills create radioactive waste in the form of tailings, which contain uranium, radium, and polonium. Consequently, uranium mining results in "the unavoidable radioactive contamination of the environment by solid, liquid and gaseous wastes". Inhalation of radon gas caused sharp increases in lung cancers among underground uranium miners employed in the 1940s and 1950s. In the 1940s and 1950s, uranium mill tailings were released with impunity into water sources, and the radium leached from these tailings contaminated thousands of miles of the Colorado River system. Between 1966 and
Uranium weakly radioactive, uranium is a toxic metal. Uranium is also a reproductive toxicant. Radiological effects are generally local because alpha radiation, the primary form of U decay, has a very short range, and will not penetrate skin. Alpha radiation from inhaled uranium has been demonstrated to cause lung cancer in exposed nuclear workers. Uranyl () ions, such as from uranium trioxide or uranyl nitrate and other hexavalent uranium compounds, have been shown to cause birth defects and immune system damage in laboratory animals. While the CDC has published one study that no human cancer has been seen as a result