Real Betis happened in 1928–29, with both teams winning their home matches (3–0 and 2–1). They played for the first time in the Spanish top division during the 1934–35 season, with a 0–3 home defeat for Sevilla and a 2–2 draw at Betis, with the latter winning the national championship. On 17 January 1943, Betis lost 5–0 at Sevilla, eventually being relegated. In the first game held at the Ramón Sánchez Pizjuán Stadium, on 21 September 1958, the "Verdiblancos" won it 4–2. In later years, several matches were also marred by violence, including: a security guard attacked by a Sevilla fan with
Real Betis with the club, leading the side to the eighth position and to the quarter-finals in the Cup Winners' Cup, where they would lose 2–5 on aggregate to eventual winners Chelsea. Aragonés was followed by the controversial reign of Javier Clemente, who spat on a fan and implied Andalusia was "another country!". The team slipped down the table, finishing 11th and being knocked out of the UEFA Cup by Bologna in the third round. For the next couple of seasons, Betis went through numerous managers, a relegation and a promotion, after which the team finished sixth in the league with Juande