Toxic multinodular goitre Toxic multinodular goitre Toxic multinodular goiter (also known as toxic nodular goiter, or Plummer's disease) is an active multinodular goiter associated with hyperthyroidism. It is a common cause of hyperthyroidism in which there is excess production of thyroid hormones from functionally autonomous thyroid nodules, which do not require stimulation from thyroid stimulating hormone (TSH). Toxic multinodular goiter is the second most common cause of hyperthyroidism (after Graves' disease) in the developed world, whereas iodine deficiency is the most common cause of hypothyroidism in developing-world countries where the population is iodine-deficient. (Decreased iodine leads to decreased thyroid hormone.) However, iodine deficiency
Roberto Goitre choirs, Carlo Pavese and Mario Pigazzini, still use the Cantar Leggendo method exclusively. Goitre dedicated all his life to musical pedagogy and choral music. It was indeed he who, at the start of the 1970s, founded the magazine La Cartellina, which is still today a very important magazine on choral music and musical pedagogy. The current editor of this magazine is Marco Boschini. Roberto Goitre Roberto Goitre (Turin, 1927 - Piacenza, 1980) was an Italian choirmaster, composer and teacher. Upon finishing his academic studies, Goitre devoted himself entirely to choral conducting. At the beginning of the 1960s, on invitation from