Iodine (medical use) Iodine (medical use) Iodine is used to treat and prevent iodine deficiency and as an antiseptic. For iodine deficiency it can be given by mouth or injection into a muscle. As an antiseptic it may be used on wounds that are wet or to disinfect the skin before surgery. Common side effects when applied to the skin include irritation and discoloration. When taken by mouth or injection side effects may include allergic reactions, goitre, and thyroid dysfunction. Use during pregnancy is recommended in regions where deficiency is common, otherwise it is not recommended. Iodine is an essential trace element. In
Cernunnos deficiency Cernunnos deficiency Cernunnos deficiency is a form of combined immunodeficiency characterized by microcephaly, due to mutations in the NHEJ1 gene, it is inherited via autosomal recessive manner Management for this condition is antiviral prophylaxis and antibiotic treatment The sign and symptoms of this condition on an affected individual are as follows: In terms of genetics the condition, Cernunnos deficiency is due to a mutation in the NHEJ1 gene, it has a cytogenetic location of 2q35, while its molecular location is 219,075,324 to 219,160,865 The pathophysiology of Cernunnos deficiency begins with normal function of "Non-homologous end-joining factor 1" gene. NHEJ1 encodes