Isabel of Braganza, Duchess of Guimarães claim to the throne of Portugal. She was also part of the succession crisis. This marriage produced three children: Isabel of Braganza, Duchess of Guimarães Dona Isabel of Braganza (1514 – 16 September 1576) was a member of the House of Braganza, daughter of Jaime, Duke of Braganza (a nephew of Manuel I of Portugal) and Leonor Pérez de Guzmán. Isabel married her cousin Infante Duarte a son of Manuel I and Maria of Aragon in 1537. Isabel was dowried with the Dukedom of Guimarães, which had belonged to her brother Teodósio I, Duke of Braganza. After the marriage, Infante
Teodósio I, Duke of Braganza of Braganza. In 1559, he remarried with Beatriz of Lencastre (1542–1623), granddaughter of Infante George of Lencastre, Duke of Coimbra. Their first child, Jaime of Braganza, died without issue in 1578, in the Battle of Alcacer Quibir. Their second child, Isabel, married the 1st Duke of Caminha. Teodósio I, Duke of Braganza Dom Teodósio I of Braganza (; 1510 – 22 September 1563) was the 5th Duke of Braganza, among other titles. He is known for ceding the title of Duke of Guimarães to Infante Duarte of Aviz, alongside some of the wealth and properties of the House of Braganza.