Mitral valve replacement cardiac surgery must be divided into pre-, intra- and postoperative. The incidence, phenomenology, and duration of symptoms diverge from patient to patient, and are difficult to define. One wonders whether any of the patients in either group in this analysis underwent any mechanical cardiac valve replacement. If so, one has to consider , described by Victor Skumin in 1978 as a “cardioprosthetic psychopathological syndrome” associated with mechanical heart valve implant and manifested by irrational fear, anxiety, depression and sleep disorder. A common postoperative complication with mitral valve surgery in a study involving 99 patients who had surgery for mitral regurgitation
Mitral insufficiency MR and mitral valve prolapse are also common in Ehlers–Danlos syndromes. Secondary mitral insufficiency is due to the dilatation of the left ventricle that causes stretching of the mitral valve annulus and displacement of the papillary muscles. This dilatation of the left ventricle can be due to any cause of dilated cardiomyopathy including aortic insufficiency, nonischemic dilated cardiomyopathy, and Noncompaction cardiomyopathy. Because the papillary muscles, chordae, and valve leaflets are usually normal in such conditions, it is also called functional mitral insufficiency. Acute MR is most often caused by endocarditis, mainly "S. aureus". Rupture or dysfunction of the papillary muscle