Inland taipan may include headache, nausea, vomiting, abdominal pain, diarrhoea, dizziness, collapse or convulsions leading to major organ effects: neurotoxicity, coagulopathy, rhabdomyolysis or renal failure/damage and finally death. Inland taipan snake venom contains potent presynaptic neurotoxins (toxins in venom that cause paralysis or muscle weakness). Also present are postsynaptic neurotoxins, which are less potent but more rapid acting than the presynaptic neurotoxins. Presynaptic neurotoxins disrupt neurotransmitter release from the axon terminal. This takes days to resolve and does not respond to antivenom. Postsynaptic neurotoxins competitively block acetylcholine receptors but the effect can be reversed by antivenom. Neurotoxic envenoming causes a progressive descending
A Gentle Creature A Gentle Creature "A Gentle Creature" (), sometimes also translated as "The Meek One", is a short story by Fyodor Dostoyevsky in 1876. The piece comes with the subtitle of "A Fantastic Story", and it chronicles the relationship between a pawnbroker and a girl that frequents his shop. The story was inspired by a news report that Dostoyevsky read in April 1876 about the suicide of a seamstress. Dostoyevsky referred to it as a "meek suicide" that "keeps haunting you for a long time." The story opens with the narrator in a frenzy about an apparent tragedy that has just