Exsanguination occur. However, the animal's inverted position allows blood to flow more precipitously and thus makes an animal regaining consciousness before it is fully exsanguinated highly unlikely. In any case, animal welfare advisory councils clearly emphasize that the time from incapacitation to start of exsanguination should be prompt; recommending a time under 15 seconds. Beyond the initial cost of purchasing a captive bolt, continued usage of the method is very inexpensive. The animal is incapacitated for the duration of the procedure, so it is one of the safest methods for the slaughterer. Slaughter by exsanguination is mandated by Judaic kashrut (kosher)
History of scientific method by revising what the search for knowledge, particularly physical knowledge, might be. The first of these, philosopher and physician Francisco Sanches, was led by his medical training at Rome, 1571–73, to search for a true method of knowing ("modus sciendi"), as nothing clear can be known by the methods of Aristotle and his followers — for example, 1) syllogism fails upon circular reasoning; 2) Aristotle's modal logic was not stated clearly enough for use in medieval times, and remains a research problem to this day. Following the physician Galen's "method of medicine", Sanches lists the methods of judgement and experience,