Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
Italian submarine Malachite she again patrolled of Ras Aamer. From 11 to 23 February, 1942 she was deployed to an area off the coast of Cyrenaica. From 8 to 21 April, 1942 again she was again deployed off the coast of Cyrenaica. From 1 June to 9 June, 1942 and then again from June 15 to 18, 1942 "Malachite" was posted northwest of Algiers. She was then relocated to patrol off Cape Blanc from 22 to 24 June. On July 16 1942 "Malachite" was sent to patrol along the Tunisian coast, however had to return to the base the next day due to