Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
The Malachite Box Stone" () inspired by "Yermak's Swans". In 2006 "Sinyushka's Well" was adapted into the musical for Russian folk instruments orchestra by Svetlana Nesterova. A docufiction feature film "Tales of the Ural Mountains" (), released by Sverdlovsk Film Studio in 1968, combined information about Bazhov's works with acted scenes from "The Mistress of the Copper Mountain", "The Stone Flower", "The Master Craftsman", "The Fire-Fairy", "The Twisted Roll", "That Spark of Life". The animated film series based on the stories from "The Malachite Box" was made at Sverdlovsk Film Studio from the early 1970s to early 1980s, on time for the 100th