Alkaloid use of Ephedra and opium poppies. Also, coca leaves have been used by South American Indians since ancient times. Extracts from plants containing toxic alkaloids, such as aconitine and tubocurarine, were used since antiquity for poisoning arrows. Studies of alkaloids began in the 19th century. In 1804, the German chemist Friedrich Sertürner isolated from opium a "soporific principle" (), which he called "morphium" in honor of Morpheus, the Greek god of dreams; in German and some other Central-European languages, this is still the name of the drug. The term "morphine", used in English and French, was given by the French
Achaea, Dreams of Divine Lands without a considerable time investment, which often sparks controversy between free players and those who paid for in-game bonuses that can cost as much as 2500 credits, the equivalent of $725 per item. The IGDA acknowledges that the system requires "delicate issues of design balance". The 2004 introduction of "gleam", an in-game addictive drug, created controversy, angering some players and reviewers who felt it sent an inappropriate message about the consequences of real-world drug use. Achaea, Dreams of Divine Lands Achaea, Dreams of Divine Lands is a roleplay-focused, text-based multi-user dungeon (MUD) released on September 9, 1997. It was published