Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
The Malachite Box "The Malachite Box" was released by Goslitizdat in 1944; the fourth by Sverdlovsk Publishing House in 1944; the fifth edition by Sovetsky Pisatel in 1947; the sixth by Goslitizdat in 1948; the seventh by Sverdlovsk Publishing House in 1949. The eighth was the last edition of "The Malachite Box" to be published during Bazhov's lifetime in 1950. In 1950 his decaying eyesight made the writing difficult. The last story "Zhabrei's Path" was published after his death. According to the All-Union Book Chamber's data as of 1 January 1981, the books in the Soviet Union were republished 253 times with a