Earwax of bacteria. Cerumen has been found to reduce the viability of a wide range of bacteria, including "Haemophilus influenzae", "Staphylococcus aureus", and many variants of "Escherichia coli", sometimes by as much as 99%. The growth of two fungi commonly present in otomycosis was also significantly inhibited by human cerumen. These antimicrobial properties are due principally to the presence of saturated fatty acids, lysozyme and, especially, to the slight acidity of cerumen (pH typically around 6.1 in normal individuals). Conversely, other research has found that cerumen can support microbial growth and some cerumen samples were found to have bacterial counts as
Substance-related disorder as an abnormal condition affecting the body of an organism: For instance, there are several known alcohol-induced diseases (e.g. alcoholic hepatitis, alcoholic liver disease, alcoholic cardiomyopathy.) Substance abuse is also often associated with premature ageing, fertility complications, brain damage and a higher risk of infectious diseases due to a weakened immune system. Long term abuse has been linked to personality changes such as depression, paranoia, anxiety which can be related to psychological disorders. It is often reported that substance abuse coincides with personality disorders, such as borderline personality disorder. It has also now been linked to severe brain damage leading