Inland taipan may include headache, nausea, vomiting, abdominal pain, diarrhoea, dizziness, collapse or convulsions leading to major organ effects: neurotoxicity, coagulopathy, rhabdomyolysis or renal failure/damage and finally death. Inland taipan snake venom contains potent presynaptic neurotoxins (toxins in venom that cause paralysis or muscle weakness). Also present are postsynaptic neurotoxins, which are less potent but more rapid acting than the presynaptic neurotoxins. Presynaptic neurotoxins disrupt neurotransmitter release from the axon terminal. This takes days to resolve and does not respond to antivenom. Postsynaptic neurotoxins competitively block acetylcholine receptors but the effect can be reversed by antivenom. Neurotoxic envenoming causes a progressive descending
A Gentle Creature (film) A Gentle Creature (film) A Gentle Creature is a 2017 drama film directed by Sergei Loznitsa. The film was created as an international co-production between France, Germany, the Netherlands, Russia, Latvia, Ukraine and Lithuania. It was selected to compete for the Palme d'Or in the main competition section at the 2017 Cannes Film Festival. The film is inspired by the short story of the same name by Fyodor Dostoyevsky. A woman lives alone on the outskirts of a village in Russia. One day she receives a parcel she had sent to her incarcerated husband, marked 'return to sender'. Shocked and