Alkaloid use of Ephedra and opium poppies. Also, coca leaves have been used by South American Indians since ancient times. Extracts from plants containing toxic alkaloids, such as aconitine and tubocurarine, were used since antiquity for poisoning arrows. Studies of alkaloids began in the 19th century. In 1804, the German chemist Friedrich Sertürner isolated from opium a "soporific principle" (), which he called "morphium" in honor of Morpheus, the Greek god of dreams; in German and some other Central-European languages, this is still the name of the drug. The term "morphine", used in English and French, was given by the French
Agnes (name) Agnes (name) Agnes is a female given name, which derives from the Greek name Ἁγνὴ "hagnē", meaning "pure" or "holy". The name passed to Italian as Agnese, to Portuguese as Inês, and to Spanish, as Inés or Inéz. It was the name of a popular Christian saint, Agnes of Rome, a fact which encouraged the wide use of the name. Agnes was the third most popular name for women in the English speaking world for more than 400 years. Its medieval pronunciation was "Annis," and its usage and many of its forms coincided with the equally popular name Anna, related