Mitral valve repair artificial mitral valve has an elevated risk of stroke. Patients with mechanical heart valves who use warfarin for anticoagulation have to be on long-term anticoagulation therapy. This means they must go to the clinic and have a lab blood draw done, typically once a month but more frequently if the level needs to be closely monitored until it is in the therapeutic range. The therapeutic range for most adults with a mechanical valve is an INR of 2.5–3.5. Finally, artificial tissue valves will wear out – on average lasting between 10 and 15 years, requiring further surgery at an advanced
History of beliefs about the human body about what he proposed as the discovery of the clitoris, stated that, "like a penis, "if you touch it, you will find it rendered a little harder and oblong to such a degree that it shows itself as a sort of male member." (There was much debate on the actual discovery of the clitoris between male European scientists and many claimed to have described it first: by dissecting the human body and writing down what was observed these European scientists could claim in their idea of the body that they had discovered or created new knowledge.) This one-sex model was