Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
The Malachite Box (1936). Inspired by the success of the tales, Bazhov continued working on them. The tales "Sinyushka's Well", "Silver Hoof", and "The Demidov Caftans" were finished even before the publication of the first "The Malachite Box" edition. By 1938 the author finished 14 stories. Because of Bazhov's tense relationship with the Communist Party, they were published under two different pen names, either under the name "P. Bragin" or simply under his initials "P. B.". The name of Vasily Hmelinin was usually in the title as well. The first edition of "The Malachite Box" was released in several versions. The first copy