Alkaloid use of Ephedra and opium poppies. Also, coca leaves have been used by South American Indians since ancient times. Extracts from plants containing toxic alkaloids, such as aconitine and tubocurarine, were used since antiquity for poisoning arrows. Studies of alkaloids began in the 19th century. In 1804, the German chemist Friedrich Sertürner isolated from opium a "soporific principle" (), which he called "morphium" in honor of Morpheus, the Greek god of dreams; in German and some other Central-European languages, this is still the name of the drug. The term "morphine", used in English and French, was given by the French
Greek divination nature. The god Prometheus gave the gift of divination to humanity. Aeschylus wrote Prometheus Bound during the 5th century BCE in which Prometheus founded all the art of civilization including divination. This he did by stealing fire from the gods and gifting this fire to humankind. The 5th century BCE telling is a re-telling of a story told by Hesiod within the 8th century BCE Greek practice made use of various techniques for divination, which are classified as direct or indirect, spontaneous or artificial. In direct divination, a divinater might experience dreams, temporary madness, or "phrensy" (frenzy); all these things