Route 1 (Paraguay) Route 1 (Paraguay) National Route 1 (in Spanish, Ruta Nacional Número 1 "Mcal. Francisco Solano López", or simply Ruta Uno) is one of the most important and one of the first highways in Paraguay, which runs from the capital city, Asunción to Itapua Department's capital, Encarnación. Crossing the departments of Central, Paraguarí, Misiones and Itapua. It starts on Avenida Eusebio Ayala, and ends at the San Roque González de Santa Cruz Bridge, on the Paraná River, traversing . The following table shows the distances traversed by Ruta 1 in each different department, and important cities that it passes by (or
History of Paraguay (to 1811) those of the Jesuits. Tensions between the natives and the Europeans grew steadily during the last years of the 18th century. Almost no archaeological research has been done in Paraguay, and the pre-Columbian history of the country is amazingly documented. What is certain is that the eastern part of the country was occupied by Guaraní Indians for at least 2 years before the Spanish conquest. Evidence indicates that those indigenous inhabitants developed a fairly sophisticated level of political autonomy, with quasi-sedentary, multivillage chiefdoms. The recorded history of Paraguay began indirectly in 1516 with the failed expedition of Juan Díaz de