Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
The Malachite Box have fallen in love with the Ural's old storyteller P. Bazhov". Selected stories have been a part of school core curriculum since the Soviet Union, and are still used for education purposes nowadays. The Ministry of Education and Science of Russia included the tales in their 2013 list of "100 Recommended Books" for schoolchildren. Their effective pedagogical influence have been noted. "The Malachite Box" became a classic of Soviet children's literature, yet the stories continued to be popular among adults as well. Mark Lipovetsky believed the situation in the author's life added to the depth of the tales and made