Paraguay Río de la Plata to the Paraná River, and finally up the Paraguay River. In 1537, they established the city of Asunción, which was the first capital of the Governorate of Paraguay and Río de la Plata. Paraguay was the epicenter of the Jesuit Missions, where the Guaraní people were educated and introduced to Christianity and European culture under the direction of the Society of Jesus in Jesuit reductions, mainly during the 17th century. However, after the expulsion of the Jesuits from Spanish territories in 1767, Paraguay increasingly became a peripheral colony, with few urban centers and settlers. Following independence
Encarnación, Paraguay Encarnación is the coldest city in Paraguay. Encarnación registered snowfall in the winter of 1975, the first time in the history of Paraguay. The annual mean temperature is 21 °C (70 °F). The annual mean relative humidity is 77%. Encarnación, Paraguay Encarnación () is a district and the capital city of Itapúa Department in Paraguay, located at the south-east of the department, on the right-hand (western) shore of the Paraná River, opposite Posadas, Argentina. The city has an area of 274 km² and a population of 93,497 (2002 Census). Encarnación is the third-largest city of Paraguay. Encarnación is connected to