History of Paraguay its capital, and Río de la Plata, with headquarters in Buenos Aires. With this decision, Asunción lost control of the Río de la Plata estuary and became dependent on Buenos Aires for maritime shipping. In 1776, the crown created the Viceroyalty of Río de la Plata; Paraguay, which had been subordinate to Lima, now became a provincial outpost of Buenos Aires. Located at the periphery of the empire, Paraguay served as a buffer state. The Portuguese blocked Paraguayan territorial expansion in the north, native tribes blocked it – until their expulsion – in the south, and the Jesuits blocked it
Illegal drug trade in Paraguay Ramón Rosa Rodríguez, the head of Paraguay's national anti-drugs agency, Secretaría Nacional Antidrogas (SENAD), was assassinated whilst delivering a report to President Juan Carlos Wasmosy. The report, which went missing, is said to have implicated ex-President Andrés Rodríguez, then a Senator, as "the chief drug kingpin in Paraguay". The border region with Brazil around Pedro Juan Caballero, in Amambay Department, is one hotspot for drug smuggling, with the Brazilian crime organizations Comando Vermelho and Primeiro Comando da Capital given as prime targets for Paraguayan anti-drugs operations in 2011. Illegal drug trade in Paraguay The illegal drug trade in Paraguay is