Mitral valve that aims at restoring proper leaflet adjustment. There are some valvular heart diseases that affect the mitral valve. Mitral stenosis is a narrowing of the valve. This can be heard as an opening snap in a heart sound which is not normally present. Classic mitral valve prolapse is caused by an excess of connective tissue that thickens the spongiosa layer of the cusp and separates collagen bundles in the fibrosa. This weakens the cusps and adjacent tissue, resulting in an increased cuspal area and lengthening of the chordae tendineae. Elongation of the chordae tendineae often causes rupture, commonly to the
Mitral valve is . Microscopically, there is no evidence of an annular structure anteriorly, where the mitral valve leaflet is contiguous with the posterior aortic root. During left ventricular diastole, after the pressure drops in the left ventricle due to relaxation of the ventricular myocardium, the mitral valve opens, and blood travels from the left atrium to the left ventricle. About 70 to 80% of the blood that travels across the mitral valve occurs during the "early filling phase" of the left ventricle. This early filling phase is due to active relaxation of the ventricular myocardium, causing a pressure gradient that allows