Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
The Malachite Box and trauma, which Bazhov endured between January 1937 and 1938, and noted that "The Malachite Box" "is filled with unprecedented for Soviet (and especially children's) literature horror". At that time Bazhov was fired from Sverdlovsk Publishing House, where he had worked since 1931, and expelled from the Communist Party for "glorification of people's enemies" in his recent book. His past as a member of the Socialist Revolutionary Party and a seminary teacher was also questionable. He was once summoned for interrogation by NKVD, but luckily his investigator was arrested the day before the meeting. The author was reinstated in the