Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
Blue Is the Warmest Colour the Warmest Color" through The Criterion Collection on 25 February 2014. As "Blue Is the Warmest Colour", the film was also released on DVD and Blu-ray Disc in Canada on 25 February 2014 by Mongrel Media, in the United Kingdom on 17 March 2014 by Artificial Eye and on 18 June 2014 in Australia by Transmission Films. In Brazil, Blu-ray manufacturing companies Sonopress and Sony DADC are refusing to produce the film because of its content. The distributor is struggling to reverse this situation. "Blue Is the Warmest Colour" grossed a worldwide total of $19,492,879. During its opening in France,