Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
Italian submarine Malachite both miss. "Malachite" was forced to dive and undergo lengthy depth charge attack. From 10 to 18 April 1941 she was posted northeast of the Gulf of Sollum. At 23:37 on April 14 "Malachite" sighted a large convoy but was prevented from attacking it due to preemptive action by the escorts. On May 20, 1941 "Malachite" together with numerous other submarines was deployed to an area between Crete, Alexandria and Sollum, to support the German invasion of Crete (Operation Merkur). "Malachite"'s area operation was south of the island of Gaidaro. On the night of June 19, 1941 while patrolling off