Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
Italian submarine Malachite Crete, "Malachite" sighted a British cruiser escorted by a destroyer. She launched two torpedoes at the target, but they both missed her by the stern. From 3 to 14 July 1941 she patrolled north of Ras Azzaz. At 20:00 on July 3 "Malachite" sighted a large cruiser (possibly ) escorted by two destroyers, and immediately launched a torpedo. There was an explosion heard, but there is no reports of this attack in British post-war documents, although some believe an escort was hit. From September 25 to October 5 1941 she patrolled off Ras Aamer. From January 20 to 27, 1942