Route 1 (Paraguay) Route 1 (Paraguay) National Route 1 (in Spanish, Ruta Nacional Número 1 "Mcal. Francisco Solano López", or simply Ruta Uno) is one of the most important and one of the first highways in Paraguay, which runs from the capital city, Asunción to Itapua Department's capital, Encarnación. Crossing the departments of Central, Paraguarí, Misiones and Itapua. It starts on Avenida Eusebio Ayala, and ends at the San Roque González de Santa Cruz Bridge, on the Paraná River, traversing . The following table shows the distances traversed by Ruta 1 in each different department, and important cities that it passes by (or
Encarnación, Paraguay Encarnación is the coldest city in Paraguay. Encarnación registered snowfall in the winter of 1975, the first time in the history of Paraguay. The annual mean temperature is 21 °C (70 °F). The annual mean relative humidity is 77%. Encarnación, Paraguay Encarnación () is a district and the capital city of Itapúa Department in Paraguay, located at the south-east of the department, on the right-hand (western) shore of the Paraná River, opposite Posadas, Argentina. The city has an area of 274 km² and a population of 93,497 (2002 Census). Encarnación is the third-largest city of Paraguay. Encarnación is connected to