Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
The Malachite Box (18 January 1939), "Izvestia" (4 April), "Pravda" and "Industria Sotsialisma" (July). However the critics disagreed on the question of authorship. Some considered "The Malachite Box" pure folklore, others thought of it was a literary work penned by Bazhov. The author himself tried to avoid the issue, joking that "questions such as these should be left to scholars". At present Bazhov's tales are generally accepted as his own literary work based on the Urals folklore. The editor of "Izvestia" called "The Malachite Box" "a valuable contribution to the Soviet fiction" and noted that "the vividness of expression and poetic richness turn