Saint Sebastian van Honthorst, Luca Signorelli, El Greco, Honoré Daumier, John Singer Sargent and Louise Bourgeois all painted Saint Sebastians. An early work by the sculptor Gianlorenzo Bernini is of Saint Sebastian. The saint is ordinarily depicted as a handsome youth pierced by arrows. Predella scenes when required, often depicted his arrest, confrontation with the Emperor, and final beheading. The illustration in the infobox is the "Saint Sebastian" of Il Sodoma, at the Pitti Palace, Florence. A mainly 17th-century subject, though found in predella scenes as early as the 15th century, was "Saint Sebastian Tended by Saint Irene" (St Irene), painted by
Jacopo Pesaro being presented by Pope Alexander VI to Saint Peter off his helmet, which sits beside the dais. Alexander had contributed 13 galleys to the mainly Venetian war effort, the Venetian fleet being commanded by Benedetto Pesaro, Jacopo's cousin. Between Pesaro's head and Peter war-galleys can be seen in action, and to the right of Alexander more sea, ending at the town of Lefkada, or perhaps one on Paphos. Apart from these specifics, the composition adapts the usual Venetian formula for an ex-voto of the donor being presented to the Virgin Mary by their patron saint, especially as developed by Giovanni Bellini, in whose studio Titian spent some time. The