Inland taipan may include headache, nausea, vomiting, abdominal pain, diarrhoea, dizziness, collapse or convulsions leading to major organ effects: neurotoxicity, coagulopathy, rhabdomyolysis or renal failure/damage and finally death. Inland taipan snake venom contains potent presynaptic neurotoxins (toxins in venom that cause paralysis or muscle weakness). Also present are postsynaptic neurotoxins, which are less potent but more rapid acting than the presynaptic neurotoxins. Presynaptic neurotoxins disrupt neurotransmitter release from the axon terminal. This takes days to resolve and does not respond to antivenom. Postsynaptic neurotoxins competitively block acetylcholine receptors but the effect can be reversed by antivenom. Neurotoxic envenoming causes a progressive descending
What Is and What Should Never Be (Supernatural) What Is and What Should Never Be (Supernatural) "What Is and What Should Never Be" is the twentieth episode of the paranormal drama television series "Supernatural"s second season. It was first broadcast on May 3, 2007 on The CW. The narrative follows series protagonist Dean Winchester (Jensen Ackles) who finds himself in an alternate reality after a confrontation with a djinn . The creature appears to have fulfilled Dean's greatest wish: that his mother had not been killed when he was a child. Dean is happy in the new world until it becomes apparent that his previous work as a