Malachite green is retained in catfish muscle longer (HL = 10 days) than is the parent molecule (HL = 2.8 days). The (oral, mouse) is 80 mg/kg. Rats fed malachite green experience "a dose-related increase in liver DNA adducts" along with lung adenomas. Leucomalachite green causes an "increase in the number and severity of changes". As leucomalachite green is the primary metabolite of malachite green and is retained in fish muscle much longer, most human dietary intake of malachite green from eating fish would be in the leuco form. During the experiment, rats were fed up to 543 ppm of leucomalachite green,
Italian submarine Malachite Spezia. In 1937 she undertook a training campaign near the Greek coast, in the Dodecanese and around Tobruk. During the Spanish Civil War, the submarine conducted a special mission between 24 August and 4 September 1937, and on August 29 she was subject to a anti-submarine search and attack. Between 1938 and 1940 "Malachite" was training and exercising for long periods around Tobruk. Upon her return to Italy, she was assigned to 47th Squadron (IV Submarine Group) based at Taranto. At the time of Italy's entrance into World War II, "Malachite" was reassigned to the X Submarine Group based at