History of Paraguay its capital, and Río de la Plata, with headquarters in Buenos Aires. With this decision, Asunción lost control of the Río de la Plata estuary and became dependent on Buenos Aires for maritime shipping. In 1776, the crown created the Viceroyalty of Río de la Plata; Paraguay, which had been subordinate to Lima, now became a provincial outpost of Buenos Aires. Located at the periphery of the empire, Paraguay served as a buffer state. The Portuguese blocked Paraguayan territorial expansion in the north, native tribes blocked it – until their expulsion – in the south, and the Jesuits blocked it
San Juan Bautista, Paraguay Mangoré, today a museum and a cultural center, is frequented by tourists. Other interesting locations in the vicinity are: Beyond San Juan Bautista, an unpaved road goes to Santa María. Another road also goes to Route 4th and to Pilar in Ñeembucú. Agustín Pío Barrios (Mangoré) was born in San Juan Misiones. He was a famous Paraguayan guitarist. The current governor is Victor H. Pereira. San Juan Bautista, Paraguay San Juan Bautista (), capital of the Department of Misiones, Paraguay, is considered the cradle of the religious mission culture. The city is the seat of the Roman Catholic Diocese of