Bushwacker (cocktail) Bushwacker (cocktail) The Bushwacker is a cocktail invented in 1975 at a bar called The Ship's Store/Sapphire Pub in Sapphire Village, Saint Thomas in the U.S. Virgin Islands. It was later enhanced and gained much notoriety at the Sandshaker Lounge in Pensacola Beach, Florida. Reference to the Virgin Island origins of the drink can be found on the Sandshaker's website. It is similar to a creamy, chocolate piña colada. The original recipe called for Vodka, Kahlua, Dark Crème de Cacao, Coco Lopez (cream of coconut), a splash of Triple sec and milk that's spun in a blender with ice and
Cooperstown cocktail probe for CYP2C9. The '+ 1' refers to the vitamin K that is given together with the warfarin to prevent any anticoagulant effect. The Cooperstown cocktail and the Cooperstown 5 + 1 cocktail are powerful tools for investigating the activity of important drug metabolising enzymes. They are used in human drug interaction studies in which the ability of a study drug to inhibit or induce cytochrome p450 enzymes is studied. Cooperstown cocktail The Cooperstown cocktail refers to a panel of four drug probes used in human pharmacokinetic studies to determine the activity of drug metabolising enzymes. The terminology 'cocktail' refers