Alkaloid use of Ephedra and opium poppies. Also, coca leaves have been used by South American Indians since ancient times. Extracts from plants containing toxic alkaloids, such as aconitine and tubocurarine, were used since antiquity for poisoning arrows. Studies of alkaloids began in the 19th century. In 1804, the German chemist Friedrich Sertürner isolated from opium a "soporific principle" (), which he called "morphium" in honor of Morpheus, the Greek god of dreams; in German and some other Central-European languages, this is still the name of the drug. The term "morphine", used in English and French, was given by the French
Geographical name changes in Turkey name changes have continued to retain their Greek origins. For example, the modern name "İzmir" derives from the former Greek name Σμύρνη "Smyrna", through the first two syllables of the phrase "εις Σμύρνην" (pronounced "is Smirnin"), which means "to Smyrna" in Greek. A similar etymology also applies to other Turkish cities with former Greek names, such as İznik (from the phrase "is Nikaean", meaning "to Nicaea"), Istanbul (from the phrase "is tan Polin" or "to the City"), or even for the Greek island of Kos, called "İstanköy" in Turkish. Nişanyan estimates that 4,200 Greek geographical locations have been changed, the