Mitral valve chordae attached to the posterior cusp. Advanced lesions—also commonly involving the posterior leaflet—lead to leaflet folding, inversion, and displacement toward the left atrium. A valve prolapse can result in mitral insufficiency which is a regurgitation or backflow of blood due to the incomplete closure of the valve. Rheumatic heart disease often affects the mitral valve. The valve may also be affected by infective endocarditis Surgery can be performed to replace or repair a damaged valve. A less invasive method is that of mitral valvuloplasty which uses a balloon catheter to open up a stenotic valve. Rarely there can be a
Mitral valve about 20% to the volume in the left ventricle prior to ventricular systole, and is known as the "atrial kick". The mitral annulus changes in shape and size during the cardiac cycle. It is smaller at the end of atrial systole due to the contraction of the left atrium around it, like a sphincter. This reduction in annulus size at the end of atrial systole may be important for the proper coapting of the leaflets of the mitral valve when the left ventricle contracts and pumps blood. Leaking valves can be corrected by mitral valve annuloplasty, a common surgical procedure