Mitral valve that aims at restoring proper leaflet adjustment. There are some valvular heart diseases that affect the mitral valve. Mitral stenosis is a narrowing of the valve. This can be heard as an opening snap in a heart sound which is not normally present. Classic mitral valve prolapse is caused by an excess of connective tissue that thickens the spongiosa layer of the cusp and separates collagen bundles in the fibrosa. This weakens the cusps and adjacent tissue, resulting in an increased cuspal area and lengthening of the chordae tendineae. Elongation of the chordae tendineae often causes rupture, commonly to the
Mitral insufficiency broad, notched P waves in several or many leads with a prominent late negative component to the P wave in lead V, and may be seen in MI, but also in mitral stenosis, and, potentially, any cause of overload of the left atrium. Thus, "P-sinistrocardiale" may be a more appropriate term. The degree of severity of MR can be quantified by the regurgitant fraction, which is the percentage of the left ventricular stroke volume that regurgitates into the left atrium. where V and V are, respectively, the volumes of blood that flow forward through the mitral valve and aortic valve