Route 1 (Paraguay) near). Route 1 (Paraguay) National Route 1 (in Spanish, Ruta Nacional Número 1 "Mcal. Francisco Solano López", or simply Ruta Uno) is one of the most important and one of the first highways in Paraguay, which runs from the capital city, Asunción to Itapua Department's capital, Encarnación. Crossing the departments of Central, Paraguarí, Misiones and Itapua. It starts on Avenida Eusebio Ayala, and ends at the San Roque González de Santa Cruz Bridge, on the Paraná River, traversing . The following table shows the distances traversed by Ruta 1 in each different department, and important cities that it passes by
Illegal drug trade in Paraguay Ramón Rosa Rodríguez, the head of Paraguay's national anti-drugs agency, Secretaría Nacional Antidrogas (SENAD), was assassinated whilst delivering a report to President Juan Carlos Wasmosy. The report, which went missing, is said to have implicated ex-President Andrés Rodríguez, then a Senator, as "the chief drug kingpin in Paraguay". The border region with Brazil around Pedro Juan Caballero, in Amambay Department, is one hotspot for drug smuggling, with the Brazilian crime organizations Comando Vermelho and Primeiro Comando da Capital given as prime targets for Paraguayan anti-drugs operations in 2011. Illegal drug trade in Paraguay The illegal drug trade in Paraguay is