Paraguay Río de la Plata to the Paraná River, and finally up the Paraguay River. In 1537, they established the city of Asunción, which was the first capital of the Governorate of Paraguay and Río de la Plata. Paraguay was the epicenter of the Jesuit Missions, where the Guaraní people were educated and introduced to Christianity and European culture under the direction of the Society of Jesus in Jesuit reductions, mainly during the 17th century. However, after the expulsion of the Jesuits from Spanish territories in 1767, Paraguay increasingly became a peripheral colony, with few urban centers and settlers. Following independence
Illegal drug trade in Paraguay Ramón Rosa Rodríguez, the head of Paraguay's national anti-drugs agency, Secretaría Nacional Antidrogas (SENAD), was assassinated whilst delivering a report to President Juan Carlos Wasmosy. The report, which went missing, is said to have implicated ex-President Andrés Rodríguez, then a Senator, as "the chief drug kingpin in Paraguay". The border region with Brazil around Pedro Juan Caballero, in Amambay Department, is one hotspot for drug smuggling, with the Brazilian crime organizations Comando Vermelho and Primeiro Comando da Capital given as prime targets for Paraguayan anti-drugs operations in 2011. Illegal drug trade in Paraguay The illegal drug trade in Paraguay is