Santa María, Paraguay Santa María, Paraguay Santa María de Fe is a town and district located in the Misiones Department in Paraguay, located about 15 km from the city of San Ignacio. The district of Santa María de Fe is located in the Eastern Region of Paraguay. It's located 253 km south of Asuncion, the capital of the country, one arrives at Santa Maria, taking the National Route Number 1, and then taking a detour between the cities of San Ignacio and Santa Rosa. The district of Santa María is bordered by the following districts: According to the 2002 Census, Santa María has
Revolt of the Comuneros (Paraguay) their streets and enforcing the new governor's rule. This wound never healed. By 1721, hatred of the Jesuits was even more intense than it was in the early 1600s. In 1717, Diego de los Reyes Balmaseda became governor of Paraguay. He purchased the position from the Spanish authorities, a practice that had spread at the time. Reyes was a merchant who had made his fortune trading exporting yerba mate from Paraguay and importing various cheap and needed manufactures back to Paraguay, so he was seen as qualified for the post by the Spanish Crown. Reyes was an open admirer of