Bonnet macaque females 3.5 to 4.5 kg. Captive monkey can live up to 35 years. The bonnet macaque feeds on fruits, nuts, seeds, flowers, invertebrates, and cereals. In southern India, this macaque exists as commensal to humans, feeding on food given by humans and raiding crops and houses. Two subspecies of bonnet macaques have been identified: "M. r. radiata" and "M. r. diluta". The bonnet macaque has a very wide range of gestures and behaviors, which can be easily differentiated. Lip smacking is one of the most common affiliative behaviors, where one individual may open and close its mouth in rapid succession,
Rhesus macaque significance because the macaque is used as an experimental model of the human immune system. In humans, the preferentially expressed antigen of melanoma (PRAME) gene family is expanded. It is actively expressed in cancers, but normally is testis-specific, possibly involved in spermatogenesis. The PRAME family has 26 members on human chromosome 1. In the macaque, it has eight, and has been very simple and stable for millions of years. The PRAME family arose in translocations in the common mouse-primate ancestor 85 million years ago, and is expanded on mouse chromosome 4. DNA microarrays are used in macaque research. For example,