Evolution of human colour vision opsins was increasing from 400 to 430. During this time, Ancestral Boreotherian had two long wave length opsins created by gene duplication, with one retaining the absolute max value of 560, equal to the ancestral value. This led to the creation of the modern human long wavelength sensitive, or red opsin. The other short wavelength sensitive opsin decreased its absolute max value to 530 and became the middle wavelength sensitive, or green-sensitive opsin. This occurred through mutations involving S180A, Y277F and T285A. The order that these mutations took place in the ancestral Boreotheria is currently not fully known. It is
Blue Is the Warmest Colour US Blu-ray/DVD sales alone). On review aggregation website Rotten Tomatoes the film has an approval rating of 90% based on 175 reviews with a weighted average of 8.2/10. The site's critical consensus is: "Raw, honest, powerfully acted, and deliciously intense, "Blue Is the Warmest Colour" offers some of modern cinema's most elegantly composed, emotionally absorbing drama." On Metacritic, which assigns a normalised rating out of 100 based on reviews from mainstream critics, the film has a score of 88 averaged from 41 reviews, indicating "universal acclaim". More than 40 critics named the film as one of the ten best of