Rio Mayo titi in deforestation is leading to the decrease in available living space for this titi monkey, forcing it to live in sympatry with another species of "Callicebus". Yet in some areas, such drastic deforestation has resulted in extremely high population density. The Rio Mayo titi is better adapted to moderately populated areas, thus overpopulation negatively impacts the species. The forests the Rio Mayo titi lives in are being destroyed for agricultural purposes, leaving little forest for the monkeys. They were only seen a few times and featured in museums until 2003 when more research was done on them. In order for
Coimbra Filho's titi preferred habitat for Coimbra Filho's titi consists of densely wooded areas, preferring the dense understory and lower canopy. However, it is able to survive in damaged or fragmented forests, which currently comprise a large portion of its range. This is due to a tolerance to highly disturbed areas, as well as the ability to subsist in areas composed primarily of young or second growth forests. While other species in "Callicebus" are native to many areas of South America from Colombia to Brazil, Peru and north Paraguay, Coimbra Filho's titi is found only in a very small area in the states