Evolution of human colour vision that are found between 450 and 625. Individuals with various forms of colour blindness such as deuteranopia and protanopia are missing human middle wavelength sensitive or long wavelength sensitive opsins. Their minimum wavelength differences are <5 but only at around 500. Protanopes, who are missing long wavelength sensitive cones, are unable to distinguish between colours in the green-yellow-red section of the electromagnetic spectrum. They find yellow, red and orange colours to have much lower brightness when compared to a trichromat. The dimming of these colours can result in confusion in many cases, such as when attempting to identify red traffic
Evolution of human colour vision hypothesized that T285A was one of the first two mutations because absolute max values would be between 532-538 which is close to the absolute value found in human middle wavelength opsins. Normal human trichromats require a mixture of three primary colours for every day colour vision. Protanopes, deuteranopes and tritanopes are all dichromats, meaning they use a mixture of two primary colours to match any specific colour that they see. Thus, they are missing one of the three wavelength sensitive cones. Trichromats with all three cone pigments intact can generally see minimum wavelength differences between <1 and <3 for wavelengths