Galantamine bulbs of "Galanthus nivalis" (common snowdrop) by the Bulgarian chemist D. Paskov and his team in 1956. The active ingredient was extracted, identified, and studied, in particular in relation to its acetylcholinesterase (AChE)-inhibiting properties. The first industrial process was developed in 1959. In addition to uses in Alzheimer's disease, galantamine has been used to treat myasthenia, myopathy, muscular dystrophy, and sensory and motor dysfunction associated with disorders of the central nervous system. In Homer's "Odyssey" the god Hermes gives Odysseus an herb with "a black root, but milklike flower" called "moly", which Hermes claims will make Odysseus immune to the
Galanthus nivalis (flowering stalk), which bears at the top a pair of bract-like spathe valves joined by a papery membrane. From between them emerges a solitary, pendulous, bell-shaped white flower, held on a slender pedicel. The flower consists of six tepals, also referred to as segments. The outer three are larger and more convex than the inner ones. The inner flower segments are usually marked on their outer surface with a green or greenish-yellow V- or U-shaped mark (sometimes described as "bridge-shaped") over the small sinus (notch) at the tip of each tepal. The inner surface has a faint green mark covering