Rio Mayo titi this species to survive, their forests need to be protected to avoid overpopulation. Different conservation groups are working to help "P. oenanthe" survive. Neotropical Primate Conservation, Proyecto Mono Tocón and Amazónicos para la Amazonia are working in the more southern areas to protect the monkey. The Rio Mayo titi is a fairly inconspicuous creature, making observation and research difficult to obtain. Therefore, the traditional use of transect observation to monitor the monkey's population, is less effective. Instead, other methods of calculating the titi monkey's density in certain areas have been taken, such as research into the species-specific calls endemic to
Coimbra Filho's titi of Bahia and Sergipe in coastal northeastern Brazil. Coimbra Filho's titi, like most titis, is a folivore-frugivore, with a diet consisting mostly of leaves, but also including various fruits. Coimbra Filho's titi generally lives in small groups consisting of three to five members. Such a group generally contains a breeding pair and its direct offspring that have yet to reach sexual maturity. However, upon reaching sexual maturity, individuals leave their natal groups, and often immigrate to new areas. Their range size varies, with some occurrences recorded of ranges as small as , and others larger than . Coimbra Filho's titi