Haptic perception by metabolic, toxic and/or immunologic factors. Examples of medical conditions that can cause neuropathies are diabetes mellitus, chronic kidney disease, thyroid dysfunction (hyper- and hypothyroidism) as well as hepatitis, liver cirrhosis and alcohol dependency. Loss of the sense of touch is a catastrophic deficit that can impair walking and other skilled actions such as holding objects or using tools. Immersive environments can recreate the feeling of haptic interaction. Exoskeletal gloves such as the Exo-Skin Soft Haptic exoskeletal interface, developed at Drexel University, can be programmed to take a patient through a program of physical therapy exercises to retrain muscles and
Pushing the Senses third track on "Pushing the Senses", was chosen as its lead single, because their European label Play it Again Sam (PIAS), were getting more involved with the band, believing the song would be a crossover to make them successful in Europe after touring with Coldplay in 2003. The single became the band's most successful single release since "Buck Rogers", reaching the top five in the UK. Grant claimed that "Tumble and Fall" is a love song, but can be interpreted in any way. In an interview with Feederweb, Grant said of the song: "Again this is about the ups and