Spaceflight radiation carcinogenesis Spaceflight radiation carcinogenesis Astronauts are exposed to approximately 50-2,000 millisieverts (mSv) while on six-month-duration missions to the International Space Station (ISS), the Moon and beyond. The risk of cancer caused by ionizing radiation is well documented at radiation doses beginning at 50 mSv and above. Related radiological effect studies have shown that survivors of the atomic bomb explosions in Hiroshima and Nagasaki, nuclear reactor workers and patients who have undergone therapeutic radiation treatments have received low-linear energy transfer (LET) radiation (x-rays and gamma rays) doses in the same 50-2000 mSv range. While in space, astronauts are exposed to radiation which
Biological effects of radiation on the epigenome due to epigenetic mechanisms in the cell. In medicine, medical diagnostic methods such as CT scans and radiation therapy expose the individual to ionizing radiation. Irradiated cells can also induce genomic instability in neighboring un-radiated cells via the bystander effect. Radiation exposure could also occur via many other channels than just ionizing radiation. In this model a single hit on a target is sufficient to kill a cell The equation used for this model is as follows: formula_1 Where k represents a hit on the cell and m represents the mass of the cell. In this model the cell has