Pneumatic artificial muscles Pneumatic artificial muscles Pneumatic artificial muscles (PAMs) are contractile or extensional devices operated by pressurized air filling a pneumatic bladder. In an approximation of human muscles, PAMs are usually grouped in pairs: one agonist and one antagonist. PAMs were first developed (under the name of "McKibben Artificial Muscles") in the 1950s for use in artificial limbs. The Bridgestone rubber company (Japan) commercialized the idea in the 1980s under the name of Rubbertuators. The retraction strength of the PAM is limited by the sum total strength of individual fibers in the woven shell. The exertion distance is limited by the tightness
Human artificial chromosome Human artificial chromosome A human artificial chromosome (HAC) is a microchromosome that can act as a new chromosome in a population of human cells. That is, instead of 46 chromosomes, the cell could have 47 with the 47th being very small, roughly 6–10megabases (Mb) in size instead of 50–250Mb for natural chromosomes, and able to carry new genes introduced by human researchers. Ideally, researchers could integrate different genes that perform a variety of functions, including disease defense. Alternative methods of creating transgenes, such as utilizing yeast artificial chromosomes and bacterial artificial chromosomes, lead to unpredictable problems. The genetic material introduced