Chemical element same atomic number, or number of protons. Nuclear scientists, however, define a pure element as one that consists of only one stable isotope. For example, a copper wire is 99.99% chemically pure if 99.99% of its atoms are copper, with 29 protons each. However it is not isotopically pure since ordinary copper consists of two stable isotopes, 69% Cu and 31% Cu, with different numbers of neutrons. However, a pure gold ingot would be both chemically and isotopically pure, since ordinary gold consists only of one isotope, Au. Atoms of chemically pure elements may bond to each other chemically in
CU-2010 and CU-2020 but they are 100,000 times better at inhibiting factor Xa and factor Xia. These inhibitory properties as well as their inhibition of plasma kallikrein and thrombin, reduces the production of thrombin and coagulation time. In vitro studies confirmed the fibrinolysis inhibition capacity of CU-2010 when present at concentrations between 100 and 1000 nM. The prolongation of coagulation (or prothrombin time, PT) occurs following either tissue factor or contact-phase stimulation and is dose-dependent. CU-2010 acts as an effective contact-phase inhibitor at antifibrinolytic concentrations. Further, when CU-2010 and CU-2020 are continuously infused, the greater inhibition of factors Xa and XIa compared to