Artificial organ almost always preceded by extensive experiments with animals. Initial testing in humans is frequently limited to those either already facing death or who have exhausted every other treatment possibility. Artificial arms and legs, or prosthetics, are intended to restore a degree of normal function to amputees. Mechanical devices that allow amputees to walk again or continue to use two hands have probably been in use since ancient times, the most notable one being the simple peg leg. Since then, the development of artificial limbs has progressed rapidly. New plastics and other materials, such as carbon fiber have allowed artificial limbs
Traditional Chinese medicines derived from the human body centuries after Li Shizhen considered the bioethical and biomedical dilemmas of using human drugs, 20th-century technological and medical advances have raised new related questions of organ transplants, transplantation medicine, organ trade, tissue banks, human cloning, and the commodification of human body parts (Awaya 1999, Nie 2002, Scheper-Hughes and Wacquant 2002). Traditional Chinese medicines derived from the human body Li Shizhen's (1597) "Bencao gangmu", the classic materia medica of traditional Chinese medicine (TCM), included 35 human drugs, including organs, bodily fluids, and excreta. Crude drugs derived from the human body were commonplace in the early history of medicine. Some of these