Tibetan macaque Tibetan macaque The Tibetan macaque ("Macaca thibetana"), also known as the Chinese stump-tailed macaque or Milne-Edwards' macaque, is found from eastern Tibet east to Guangdong and north to Shaanxi in China. It has also been reported from northeastern India. This species lives in subtropical forests (mixed deciduous to evergreen) at altitudes from above sea level. There are four recognized subspecies: The Tibetan macaque is the largest species of macaque and one of the largest monkeys found in Asia. Only the proboscis monkey and the larger species of gray langur come close to match their size among Asian monkeys. Males are
Rhesus macaque significance because the macaque is used as an experimental model of the human immune system. In humans, the preferentially expressed antigen of melanoma (PRAME) gene family is expanded. It is actively expressed in cancers, but normally is testis-specific, possibly involved in spermatogenesis. The PRAME family has 26 members on human chromosome 1. In the macaque, it has eight, and has been very simple and stable for millions of years. The PRAME family arose in translocations in the common mouse-primate ancestor 85 million years ago, and is expanded on mouse chromosome 4. DNA microarrays are used in macaque research. For example,