Evolution of human colour vision opsins was increasing from 400 to 430. During this time, Ancestral Boreotherian had two long wave length opsins created by gene duplication, with one retaining the absolute max value of 560, equal to the ancestral value. This led to the creation of the modern human long wavelength sensitive, or red opsin. The other short wavelength sensitive opsin decreased its absolute max value to 530 and became the middle wavelength sensitive, or green-sensitive opsin. This occurred through mutations involving S180A, Y277F and T285A. The order that these mutations took place in the ancestral Boreotheria is currently not fully known. It is
What Is to Be Done? (novel) Is to Be Done?" is one of the sources of inspiration for Rand's thought. For example, the book's main character Lopuhov says "I am not a man to make sacrifices. And indeed there are no such things. One acts in the way that one finds most pleasant." Vladimir Nabokov's final novel in Russian, "The Gift", ridicules "What is to Be Done?" in its fourth chapter. What Is to Be Done? (novel) What Is To Be Done? (; also translated as What Shall We Do? and literally translated as "What To Do?") is an 1863 novel written by the Russian philosopher,