Toque macaque Toque macaque The toque macaque ("Macaca sinica") is a reddish-brown-coloured Old World monkey endemic to Sri Lanka, where it is known as the "rilewa" or "rilawa" (Sinhala රිළවා), (hence "rillow" in the "Oxford English Dictionary"). With age, the face of females turn slightly pink, prominent in the subsp. "sinica". "M. s. sinica" is found from the Vavuniya, Mannar, up to the lowlands of Anuradhapura, Polonnaruwa, Puttalam, and Kurunegala along the arid zone of Monaragala, and Hambantota districts. "M. s. aurifrons" can be found sympatrically with subsp. "sinica" within intermediate regions of the country, such as Kegalle, parts of Kurunegala. They
Rhesus macaque significance because the macaque is used as an experimental model of the human immune system. In humans, the preferentially expressed antigen of melanoma (PRAME) gene family is expanded. It is actively expressed in cancers, but normally is testis-specific, possibly involved in spermatogenesis. The PRAME family has 26 members on human chromosome 1. In the macaque, it has eight, and has been very simple and stable for millions of years. The PRAME family arose in translocations in the common mouse-primate ancestor 85 million years ago, and is expanded on mouse chromosome 4. DNA microarrays are used in macaque research. For example,