Bergamot essential oil for a number of grapefruit–drug interactions. In one case study, a patient who consumed four liters of Earl Grey tea per day suffered paresthesias, fasciculations and muscle cramps. Bergamot essential oil Bergamot essential oil is a cold-pressed essential oil produced by cells inside the rind of a bergamot orange fruit. It is a common flavoring and top note in perfumes. The scent of bergamot essential oil is similar to a sweet light orange peel oil with a floral note. The "sfumatura" or slow-folding process was the traditional technique for manually extracting the bergamot oil. By more modern methods, the oil
Bergamot orange for grapefruit–drug interactions in which the consumption of the juice affects the metabolism of a variety of pharmaceutical drugs. Used in cosmetics and perfume products, bergamot may cause skin irritation. In the past, psoralen extracted from bergamot oil has been used in tanning accelerators and sunscreens. These substances have been known to be photocarcinogenic since 1959, but they were only banned from sunscreens in 1995. These photocarcinogenic substances were banned years after they had caused many cases of malignant melanoma and deaths. As of 2017, clinical research conducted on bergamot oil has been of poor quality, with no conclusions possible