Arunachal macaque It is the first species of macaque to have been discovered since 1903, when the Indonesian Pagai Island macaque was discovered. This monkey was reported on the basis of a good quality photograph as the holotype. In 2011, some researchers suggested, on the basis of morphological variation within the Assamese macaque, that it might be better treated as a subspecies. Subsequently, it was also discovered in Bhutan, where it was observed and photographed in the Trashi Yangshi area in 2006. The Arunachal macaque is compactly built and has a very dark face. It lives at high altitudes, between 2000 m
Rhesus macaque significance because the macaque is used as an experimental model of the human immune system. In humans, the preferentially expressed antigen of melanoma (PRAME) gene family is expanded. It is actively expressed in cancers, but normally is testis-specific, possibly involved in spermatogenesis. The PRAME family has 26 members on human chromosome 1. In the macaque, it has eight, and has been very simple and stable for millions of years. The PRAME family arose in translocations in the common mouse-primate ancestor 85 million years ago, and is expanded on mouse chromosome 4. DNA microarrays are used in macaque research. For example,