Assam macaque Assam macaque The Assam macaque ("Macaca assamensis") is a macaque of the Old World monkey family native to South and Southeast Asia. Since 2008, the species has been listed as Near Threatened by IUCN, as it is experiencing significant declines due to hunting, habitat degradation and fragmentation. The Assam macaque has a yellowish-grey to dark brown pelage. The facial skin is dark brownish to purplish. The head has a dark fringe of hair on the cheeks directed backwards to the ears. The hair on the crown is parted in the middle. The shoulders, head and arms tend to be paler
Rhesus macaque significance because the macaque is used as an experimental model of the human immune system. In humans, the preferentially expressed antigen of melanoma (PRAME) gene family is expanded. It is actively expressed in cancers, but normally is testis-specific, possibly involved in spermatogenesis. The PRAME family has 26 members on human chromosome 1. In the macaque, it has eight, and has been very simple and stable for millions of years. The PRAME family arose in translocations in the common mouse-primate ancestor 85 million years ago, and is expanded on mouse chromosome 4. DNA microarrays are used in macaque research. For example,