Crab-eating macaque DNA transfer method that produced "Dolly" the sheep. This makes Zhong Zhong and Hua Hua the first primates to be cloned using the somatic cell nuclear transfer method. Crab-eating macaque The crab-eating macaque ("Macaca fascicularis"), also known as the long-tailed macaque, is a cercopithecine primate native to Southeast Asia. It is referred to as the cynomolgus monkey in laboratories. It has a long history alongside humans; they have been alternately seen as agricultural pests, sacred animals in some temples, and more recently, the subject of medical experiments. The crab-eating macaque lives in matrilineal social groups with a female dominance hierarchy,
Rhesus macaque The X chromosome has three times more rearrangements than other chromosomes. The macaque gained 1,358 genes by duplication. Triangulation of human, chimpanzee, and macaque sequences showed expansion of gene families in each species. The "PKFP" gene, important in sugar (fructose) metabolism, is expanded in macaques, possibly because of their high-fruit diet. So are genes for the olfactory receptor, cytochrome P450 (which degrades toxins), and CCL3L1-CCL4 (associated in humans with HIV susceptibility). Immune genes are expanded in macaques, relative to all four great ape species. The macaque genome has 33 major histocompatibility genes, three times those of human. This has clinical