Pneumatic artificial muscles conventional electric motors and hydraulic cylinders. Pneumatic artificial muscles Pneumatic artificial muscles (PAMs) are contractile or extensional devices operated by pressurized air filling a pneumatic bladder. In an approximation of human muscles, PAMs are usually grouped in pairs: one agonist and one antagonist. PAMs were first developed (under the name of "McKibben Artificial Muscles") in the 1950s for use in artificial limbs. The Bridgestone rubber company (Japan) commercialized the idea in the 1980s under the name of Rubbertuators. The retraction strength of the PAM is limited by the sum total strength of individual fibers in the woven shell. The exertion
Human artificial chromosome resulted in a human artificial chromosome that is mitotically stable. 21HAC was also able to be transferred into cells from a variety of species (mice, chickens, humans). Using 21HAC, researchers were able to insert a herpes simplex virus- thymidine kinase coding gene into tumor cells. This "suicide gene" is required to activate many antiviral medications. These targeted tumor cells were successfully, and selectively, terminated by the antiviral drug ganciclovir in a population including healthy cells. This research opens a variety of opportunities for using HACs in gene therapy. In 2011, researchers formed a human artificial chromosome by truncating chromosome 14.