Evolution of human colour vision opsins was increasing from 400 to 430. During this time, Ancestral Boreotherian had two long wave length opsins created by gene duplication, with one retaining the absolute max value of 560, equal to the ancestral value. This led to the creation of the modern human long wavelength sensitive, or red opsin. The other short wavelength sensitive opsin decreased its absolute max value to 530 and became the middle wavelength sensitive, or green-sensitive opsin. This occurred through mutations involving S180A, Y277F and T285A. The order that these mutations took place in the ancestral Boreotheria is currently not fully known. It is
The Colour Out of Space of his stylistically and conceptually finest short stories." Joshi praises the work as one of Lovecraft's best and most frightening, particularly for the vagueness of the description of the story's eponymous horror. He also lauded the work as Lovecraft's most successful attempt to create something entirely outside of the human experience, as the creature's motive (if any) is unknown and it is impossible to discern whether or not the "colour" is emotional, moral, or even conscious. His only criticism is that it is "just a little too long". The text of "The Colour Out of Space", like many of Lovecraft's