Spaceflight radiation carcinogenesis gamma rays that produce the same biological effect are called relative biological effectiveness (RBE) factors. The types of tumors in humans who are exposed to space radiation will be different from those who are exposed to low-LET radiation. This is evidenced by a study that observed mice with neutrons and have RBEs that vary with the tissue type and strain. The various approaches to setting acceptable levels of radiation risk are summarized below: NCRP Report No. 153 provides a more recent review of cancer and other radiation risks. This report also identifies and describes the information needed to make radiation
Biological effects of radiation on the epigenome of the MGMT promoter. Almost all human cancers include hypomethylation of LINE1 elements. Various studies depict that the hypomethylation of LINE1 correlates with a decrease in survival after both chemotherapy and radiotheraphy. DMNT inhibitors are being explored in the treatment of malignant tumors. Recent in-vitro studies show that DNMT inhibitors can increase the effects of other anti-cancer drugs. Knowledge of in-vivo effect of DNMT inhibitors are still being investigated. The long term effects of the use of DNMT inhibitors are still unknown. Biological effects of radiation on the epigenome Ionizing radiation can cause biological effects which are passed on to