Pagai Island macaque a result, the water levels in the forest rivers fluctuate to a much greater degree than before. The alternating flooding and low water levels has also caused an increase in the population of malarial mosquitoes. Pagai Island macaque The Pagai Island macaque ("Macaca pagensis"), also known as the Pagai macaque or Bokkoi, is an Old World monkey endemic to the Mentawai Islands off the west coast of Sumatra. It is listed as critically endangered on the IUCN Red List due to its ever-shrinking habitat. "Macaca pagensis" formerly included the overall darker Siberut macaque as a subspecies, but this arrangement is
Rhesus macaque significance because the macaque is used as an experimental model of the human immune system. In humans, the preferentially expressed antigen of melanoma (PRAME) gene family is expanded. It is actively expressed in cancers, but normally is testis-specific, possibly involved in spermatogenesis. The PRAME family has 26 members on human chromosome 1. In the macaque, it has eight, and has been very simple and stable for millions of years. The PRAME family arose in translocations in the common mouse-primate ancestor 85 million years ago, and is expanded on mouse chromosome 4. DNA microarrays are used in macaque research. For example,