The Sign of the Four and play adaptations insure this book: The Sign of the Four was also adapted for radio by Bert Coules in 1989 as part of BBC Radio 4's complete audio Sherlock Holmes, with Clive Merrison as Holmes, Michael Williams as Watson, and featuring Brian Blessed as Jonathan Small. The Sign of the Four The Sign of the Four (1890), also called The Sign of Four, is the second novel featuring Sherlock Holmes written by Sir Arthur Conan Doyle. Doyle wrote four novels and 56 short stories featuring the fictional detective. The story is set in 1888. "The Sign of the Four"
Sherlock Holmes pastiches Ukraine, giving Arthur Conan Doyle the task to convince everyone that he was just an imaginary character. With the help of his serum, Holmes prolonged his life for several decades. In 1990s he indirectly helped Martin Mystère to capture a villain who found a formula of his serum. Leah Moore and John Reppion's "The Trial of Sherlock Holmes" (2009) and Scott Beatty's "Sherlock Holmes Year One" (2011) published by Dynamite Entertainment. Ian Edginton wrote the 2010 Wildstorm comic book limited series "Victorian Undead" which pitted Holmes against zombies. New Paradigm Studios in August 2012 debuted "Watson and Holmes" digital comic