Rio Mayo titi this species to survive, their forests need to be protected to avoid overpopulation. Different conservation groups are working to help "P. oenanthe" survive. Neotropical Primate Conservation, Proyecto Mono Tocón and Amazónicos para la Amazonia are working in the more southern areas to protect the monkey. The Rio Mayo titi is a fairly inconspicuous creature, making observation and research difficult to obtain. Therefore, the traditional use of transect observation to monitor the monkey's population, is less effective. Instead, other methods of calculating the titi monkey's density in certain areas have been taken, such as research into the species-specific calls endemic to
Coimbra Filho's titi fragment of the population, limiting reproductive options. The species' natural geographical distribution also contributes a threat to the species. Coimbra Filho's titi only naturally occurs in the Atlantic coastal forests in northeastern Brazil. This is a relatively small area in the states of Sergipe and Bahia. Due to this small range, any disturbances to these areas pose a larger than normal threat to the species' survival. More than anything else, however, human interference is the source of many problems to Coimbra Filho's titi. The areas around and inside its habitat are being developed, including paving roads and the promotion of