Rio Mayo titi in deforestation is leading to the decrease in available living space for this titi monkey, forcing it to live in sympatry with another species of "Callicebus". Yet in some areas, such drastic deforestation has resulted in extremely high population density. The Rio Mayo titi is better adapted to moderately populated areas, thus overpopulation negatively impacts the species. The forests the Rio Mayo titi lives in are being destroyed for agricultural purposes, leaving little forest for the monkeys. They were only seen a few times and featured in museums until 2003 when more research was done on them. In order for
White-eared titi be quite tolerant of habitat disturbance. In Bolivia, the white-eared titi is found in the upper parts of the Mamoré, Grande, and San Miguel river basins, east of the Manique River in Beni and in the forests surrounding the city of Santa Cruz de la Sierra. Its range extends north to southern Rondônia in Brazil. The white-eared titi is considered to be of least concern on the International Union for Conservation of Nature (IUCN) Red List. The species is not considered threatened due to its adaptability and abundance over a relatively wide range, and despite having a decreasing population trend