Group 11 element Group 11 element Group 11, by modern IUPAC numbering, is a group of chemical elements in the periodic table, consisting of copper (Cu), silver (Ag), and gold (Au). Roentgenium (Rg) is also placed in this group in the periodic table, although no chemical experiments have yet been carried out to confirm that it behaves like the heavier homologue to gold. Group 11 is also known as the "coinage metals", due to their former usage. They were most likely the first three elements discovered. Copper, silver, and gold all occur naturally in elemental form. All the elements of the group except
CU-2010 and CU-2020 CU-2010 and CU-2020 CU-2010 and CU-2020 are synthetic compounds that act as serine protease inhibitors. These were developed in 2010 to replace the use of aprotinin during and after cardiac surgery, including surgeries with cardiopulmonary bypass which cause blood loss and hemorrhagic complications. CU-2010 and CU-2020 were developed to avoid many issues associated with the use of aprotinin, including the risk of an allergic reaction and infection. Since the isolation of aprotinin is expensive, a drug with a simpler synthesis was desired. CU-2010 has a molecular weight of 700 Da and binds to the active site of serine proteases, like