Macaque the other monkey's mouth. Several species of macaque are used extensively in animal testing, particularly in the neuroscience of visual perception and the visual system. Nearly all (73–100%) pet and captive rhesus macaques are carriers of the herpes B virus. This virus is harmless to macaques, but infections of humans, while rare, are potentially fatal, a risk that makes macaques unsuitable as pets. Urban performing macaques also carried simian foamy virus, suggesting they could be involved in the species-to-species jump of similar retroviruses to humans. In Vietnam, macaque is eaten by some people as bushmeat. In January 2018, scientists in
Rhesus macaque significance because the macaque is used as an experimental model of the human immune system. In humans, the preferentially expressed antigen of melanoma (PRAME) gene family is expanded. It is actively expressed in cancers, but normally is testis-specific, possibly involved in spermatogenesis. The PRAME family has 26 members on human chromosome 1. In the macaque, it has eight, and has been very simple and stable for millions of years. The PRAME family arose in translocations in the common mouse-primate ancestor 85 million years ago, and is expanded on mouse chromosome 4. DNA microarrays are used in macaque research. For example,