Macaque Macaque The macaques ( or ) constitute a genus (Macaca) of Old World monkeys of the subfamily Cercopithecinae. The 23 species of macaques are distributed throughout Asia, North Africa and (in one instance) Gibraltar. Macaques are principally frugivorous, although their diet also includes seeds, leaves, flowers, and tree bark, and some, such as the crab-eating macaque, subsist on a diet of invertebrates and occasionally small vertebrates. Macaques are found in a variety of habitats throughout the Asian continent, and are extremely adaptable. All macaque social groups are arranged around dominant, matriarchal females. They also have learned to live with humans,
Rhesus macaque Michael Katze of University of Washington, Seattle, infected macaques with 1918 and modern influenzas. The DNA microarray showed the macaque genomic response to human influenza on a cellular level in each tissue. Both viruses stimulated innate immune system inflammation, but the 1918 flu stimulated stronger and more persistent inflammation, causing extensive tissue damage, and it did not stimulate the interferon-1 pathway. The DNA response showed a transition from innate to adaptive immune response over seven days. The full sequence and annotation of the macaque genome is available on the Ensembl genome browser. Rhesus macaque The rhesus macaque ("Macaca mulatta") is