Horses in warfare of today's English saddle. Both the Scythians and Assyrians used pads with added felt attached with a surcingle or girth around the horse's barrel for increased security and comfort. Xenophon mentioned the use of a padded cloth on cavalry mounts as early as the 4th century BC. The saddle with a solid framework, or "tree", provided a bearing surface to protect the horse from the weight of the rider, but was not widespread until the 2nd century AD. However, it made a critical difference, as horses could carry more weight when distributed across a solid saddle tree. A solid tree,
Animal testing on rodents Epigenetics, and the Inescapable Problem of Animal Constraint. Animal Models of Behavior Genetics, (Springer, 2016), pp. 265–301. Animal testing on rodents Rodents are commonly used in animal testing, particularly mice and rats, but also guinea pigs, hamsters, gerbils and others. Mice are the most commonly used vertebrate species, due to their availability, size, low cost, ease of handling, and fast reproduction rate. In the UK in 2015, there were 3.33 million procedures on rodents (80% of total procedures that year). The most common species used were mice (3.03 million procedures, or 73% of total) and rats (268,522, or 6.5%). Other