Carotid endarterectomy 7 carotid stent systems as safe and effective in patients at increased risk of complications for carotid surgery and 1 carotid stent system for patients at average or usual risk of carotid surgery. The SAPPHIRE study of patients at high surgical risk for carotid surgery demonstrated non-inferiority for carotid stenting compared to carotid surgery. The CREST trial, the largest trial comparing carotid surgery to carotid stenting in over 2,500 patients found that carotid artery stenting resulted in a stroke rate of 6.4% versus 4.7% for endarterectomy at 4 years. However, carotid endarterectomy was associated with a slightly higher rate of
Carotid body sustentacular supportive cells. The carotid body contains the most vascularized tissue in the human body . The thyroid gland is very vascular, but not quite as much as the carotid body. The carotid body functions as a sensor: it responds to a stimulus, primarily O partial pressure, which is detected by the type I (glomus) cells, and triggers an action potential through the afferent fibers of the glossopharyngeal nerve, which relays the information to the central nervous system. The carotid body chemoreceptors are primarily sensitive to decreases in the partial pressure of oxygen (P). This is in contrast to the