Girth (tack) strip down its center, it may cause discomfort. It is also best if it has some "give" to it, which makes it more comfortable for the horse. Many riders also choose a girth that allows for extra elbow room, so the horse is not restricted as his leg moves backward. To measure for a girth, the saddle with a pad should be placed on the horse. A measuring tape is then used to measure from the middle hole of the billet on one side, under the horse's belly, to the middle billet on the other side. If a girth is
Organ-on-a-chip it can facilitate cross-species extrapolation. Used in conjunction with PBPK models, the devices permit an estimation of effective concentrations that can be used for studies with animal models or predict the human response. In the development of multicompartment devices, representations of the human body such as those in used PBPK models can be used to guide the device design with regard to the arrangement of chambers and fluidic channel connections to augment the drug development process, resulting in increased success in clinical trials. Organ-on-a-chip An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics