Sistine Chapel ceiling and the relatively conservative concept of the relationship between Eve and her Creator adheres closely to Jacopo's design. Other panels on the ceiling, most particularly the iconic "Creation of Adam" show "... unprecedented invention". The ceiling of the Sistine Chapel was to have a profound effect upon other artists, even before it was completed. Vasari, in his Life of Raphael, tells us that Bramante, who had the keys to the chapel, let Raphael in to examine the paintings in Michelangelo's absence. On seeing Michelangelo's prophets, Raphael went back to the picture of the Prophet Isaiah that he was painting on
Descent from Mount Sinai (Sistine Chapel) Descent from Mount Sinai (Sistine Chapel) The Descent from Mount Sinai is a fresco by the Italian Renaissance painter Cosimo Rosselli and his assistants, executed in 1481–1482 and located in the Sistine Chapel, Rome. On 27 October 1480, several Florentine painters left for Rome, where they had been called as part of the reconciliation project between Lorenzo de' Medici, the "de facto" ruler of Florence, and Pope Sixtus IV. The Florentines started to work in the Sistine Chapel as early as spring 1481, along with Pietro Perugino, who was already there. Rosselli brought with him his son-in-law, Piero di Cosimo,