Sistine Chapel ceiling picture is crowded with figures and separate incidents as the various individuals who have been attacked by snakes struggle and die or turn toward the icon that will save them. This is the most Mannerist of Michelangelo's earlier compositions at the Sistine Chapel, picking up the theme of human distress begun in the "Great Flood" scene and carrying it forward into the torment of lost souls in the "Last Judgement", which was later painted below. Between the large pendentives that support the vault are windows, six on each side of the chapel. There were two more windows in each end
Descent from Mount Sinai (Sistine Chapel) Descent from Mount Sinai (Sistine Chapel) The Descent from Mount Sinai is a fresco by the Italian Renaissance painter Cosimo Rosselli and his assistants, executed in 1481–1482 and located in the Sistine Chapel, Rome. On 27 October 1480, several Florentine painters left for Rome, where they had been called as part of the reconciliation project between Lorenzo de' Medici, the "de facto" ruler of Florence, and Pope Sixtus IV. The Florentines started to work in the Sistine Chapel as early as spring 1481, along with Pietro Perugino, who was already there. Rosselli brought with him his son-in-law, Piero di Cosimo,