Carotid body A decrease in oxygen partial pressure, an increase in carbon dioxide partial pressure, and a decrease in arterial pH can all cause depolarization of the cell membrane, and they affect this by blocking potassium currents. This reduction in the membrane potential opens voltage-gated calcium channels, which causes a rise in intracellular calcium concentration. This causes exocytosis of vesicles containing a variety of neurotransmitters, including acetylcholine, noradrenaline, dopamine, adenosine, ATP, substance P, and met-enkephalin. These act on receptors on the afferent nerve fibres which lie in apposition to the glomus cell to cause an action potential. The feedback from the carotid
Errors of the Human Body Errors of the Human Body Errors of the Human Body is a 2012 psychological thriller directed by Eron Sheean and starring Michael Eklund. Dr. Geoff Burton (Eklund), a brilliant genetics researcher, is invited to a lab in Dresden, only to discover a lethal virus is being created, which he may have unintentionally caused and be its first victim. This mystery is set against Dr. Burton trying to find redemption and peace from a past haunted by the death of his infant son. While showing a short film at Berlinale in 2006, Sheean met a scientist from the Max Planck Institute