Carotid body A decrease in oxygen partial pressure, an increase in carbon dioxide partial pressure, and a decrease in arterial pH can all cause depolarization of the cell membrane, and they affect this by blocking potassium currents. This reduction in the membrane potential opens voltage-gated calcium channels, which causes a rise in intracellular calcium concentration. This causes exocytosis of vesicles containing a variety of neurotransmitters, including acetylcholine, noradrenaline, dopamine, adenosine, ATP, substance P, and met-enkephalin. These act on receptors on the afferent nerve fibres which lie in apposition to the glomus cell to cause an action potential. The feedback from the carotid
The Human Body (TV series) July 2001 and includes a 50-minute feature on "The Making of the Human Body" - A final overview that reveals the techniques and developments that made the series possible. The series was adapted into a film released for IMAX cinemas. The film won the Giant Screen Theatre Association's Best Film For Lifelong Learning award. The book accompanying the series was written by Anthony Smith. According to one review, "Smith transcends anatomical trivia to record our bodies' powerful tale with empathy and clarity." The Human Body (TV series) The Human Body is a seven-part documentary series, first shown on 20 May