Presidency of James Monroe knowledge of the northwest region of the Louisiana Purchase. The expedition suffered several setbacks, but the efforts of scientists such as Edwin James advanced U.S. knowledge of the flora and fauna of the region. The federal government had taken control of the Yazoo lands from Georgia in the Compact of 1802; as part of that agreement, President Jefferson promised to remove Native Americans from the region. Georgians pressed Monroe to remove the remaining Native Americans to regions west of the Mississippi River, but the Native Americans rejected the Monroe administration's offers to purchase their land. As Monroe was unwilling to
James Monroe of Virginia and rose to national prominence as a diplomat in France when he helped negotiate the Louisiana Purchase in 1803. During the War of 1812, Monroe served in critical roles as Secretary of State and the Secretary of War under President James Madison. Facing little opposition from the waning Federalist Party, Monroe was easily elected president in 1816, winning over eighty percent against Rufus King (who hadn't even been chosen by a convention since the Federalists were too weak to organize) of the electoral vote and becoming the last president during the First Party System era of American politics.