Sistine Chapel ceiling and the relatively conservative concept of the relationship between Eve and her Creator adheres closely to Jacopo's design. Other panels on the ceiling, most particularly the iconic "Creation of Adam" show "... unprecedented invention". The ceiling of the Sistine Chapel was to have a profound effect upon other artists, even before it was completed. Vasari, in his Life of Raphael, tells us that Bramante, who had the keys to the chapel, let Raphael in to examine the paintings in Michelangelo's absence. On seeing Michelangelo's prophets, Raphael went back to the picture of the Prophet Isaiah that he was painting on
Restoration of the Sistine Chapel frescoes watercolour, to integrate the pictorial material. These areas are distinctively textured with vertical brushstrokes, not visible from a distance but easily discernible as restoration work when viewed close up. Certain small areas were left unrestored, in order to maintain a physical record of the previous restorations that had taken place, for example, an area left with overpainting and candle wax, and another area demonstrating the attempt to counteract salination with oil. Once the many layers of candle wax, varnish, and animal glue were removed from the surface of the Sistine Chapel frescoes, they became subject to dangers that could not