Chambon Chambon A chambon is a piece of horse tack. It is a strap that runs forward from the bottom of the girth or surcingle, and forks. The forks continue to a ring on either side of the bridle or halter, at the base of the crownpiece. Running through those rings, the forks follow the cheekpieces to the bit. They may attach to the bit or pass through the bit rings and attach to themselves below the horse's neck. A chambon prevents the horse from raising its head beyond a fixed point. Raising the head causes the length of the chambon
Organ-on-a-chip it can facilitate cross-species extrapolation. Used in conjunction with PBPK models, the devices permit an estimation of effective concentrations that can be used for studies with animal models or predict the human response. In the development of multicompartment devices, representations of the human body such as those in used PBPK models can be used to guide the device design with regard to the arrangement of chambers and fluidic channel connections to augment the drug development process, resulting in increased success in clinical trials. Organ-on-a-chip An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics