Carotid stenting stenosis of the internal carotid artery. Carotid stenting may be considered an alternative to carotid surgery in average surgical risk patients, albeit with a higher risk of death or stroke as seen in the SAPPHIRE and CREST trials. Features that favor carotid stenting include non-atherosclerotic cause of the stenosis (fibrodysplasia, radiation, early post-surgical stenosis or flap) an experienced center and experienced physician performing the procedure. Features that make stent placement more difficult include significant aortic arch tortuosity, thrombus containing lesions, occluded carotid artery, heavily calcified vessels, symptomatic patients and very tortuous and twisting vessels. None of these affect open, surgical
Carotid body sustentacular supportive cells. The carotid body contains the most vascularized tissue in the human body . The thyroid gland is very vascular, but not quite as much as the carotid body. The carotid body functions as a sensor: it responds to a stimulus, primarily O partial pressure, which is detected by the type I (glomus) cells, and triggers an action potential through the afferent fibers of the glossopharyngeal nerve, which relays the information to the central nervous system. The carotid body chemoreceptors are primarily sensitive to decreases in the partial pressure of oxygen (P). This is in contrast to the