Scientific American Frontiers 1993. Actor Alan Alda became the permanent host starting in the fall season of 1993 and continued until the show ended in 2005. So the show was also billed as "Alan Alda in Scientific American Frontiers". Alda's tenure has been notable for his humble and often humorous approach: in one memorable segment, he became car sick while driving an experimental, virtual reality vehicle. In 2005, Alda published his first round of memoirs, "Never Have Your Dog Stuffed: and Other Things I've Learned", published by Random House (); in the book, he recalls his intestines becoming strangulated while on location in
Things Which Have Never Yet Been Done (Skyler Wexler) undergoes bone marrow extraction to donate to Cosima in an attempt to cure Cosima's illness. Alison and her husband Donnie (Kristian Bruun) attempt to bury Dr. Aldous Leekie's body, while Helena attempts to escape from the ranch of the Proletheans, a religious extremist group. "Things Which Have Never Yet Been Done" marked the first on-screen appearance of Kathryn Alexandre, who also works on the show as Maslany's "clone double" when filming scenes where multiple clones interact. The episode was filmed at various locations in Toronto and the title was taken from Francis Bacon's work "Novum Organum". It was