Girth (tack) sensitive horses to protect the barrel of the horse, and some styles of girth come with attached or removable sheepskin liners that perform the same function. A dressage girth, or Lonsdale girth, is shorter than the usual girths used on other saddles. This is because the dressage saddle has longer billets, to keep the buckles out from under the rider's leg, and so a shorter girth may be used. Dressage girths can be made of all the materials, and in all the styles, mentioned before, and also can be made entirely of very strong elastic. An overgirth or surcingle is
Organ-on-a-chip it can facilitate cross-species extrapolation. Used in conjunction with PBPK models, the devices permit an estimation of effective concentrations that can be used for studies with animal models or predict the human response. In the development of multicompartment devices, representations of the human body such as those in used PBPK models can be used to guide the device design with regard to the arrangement of chambers and fluidic channel connections to augment the drug development process, resulting in increased success in clinical trials. Organ-on-a-chip An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics