Horse blanket rear, but usually it has no other straps or attachments. It is intended to be used on a horse while the animal is being led or held by a person, and not left on an unattended horse. In windy weather, a loose surcingle may be added to prevent the cooler from blowing completely off. A traditionally-shaped blanket of loosely crocheted cotton, called an "anti-sweat sheet", is used to absorb moisture. Often used alone to wick moisture from the surface of the horse, if placed under a cooler, it is removed when it becomes wet. A "barrier blanket" is sometimes used
Organ-on-a-chip it can facilitate cross-species extrapolation. Used in conjunction with PBPK models, the devices permit an estimation of effective concentrations that can be used for studies with animal models or predict the human response. In the development of multicompartment devices, representations of the human body such as those in used PBPK models can be used to guide the device design with regard to the arrangement of chambers and fluidic channel connections to augment the drug development process, resulting in increased success in clinical trials. Organ-on-a-chip An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics