Branch of glossopharyngeal nerve to carotid sinus Branch of glossopharyngeal nerve to carotid sinus The branch of glossopharyngeal nerve to the carotid sinus (Hering's nerve) is a small nerve in the neck, that innervates the carotid sinus and the carotid body. It is a branch of the glossopharyngeal nerve that runs downwards, anterior to the internal carotid artery. It communicates with the vagus nerve and sympathetic trunk and then divides in the angle of the bifurcation of the common carotid artery to innervate the carotid body and carotid sinus. It carries impulses from the baroreceptors in the carotid sinus to the vasomotor center in the brainstem (to
Carotid body may involve mitochondrial oxygen sensors and the haem-containing cytochromes that undergo reversible one-electron reduction during oxidative-phosphorylation. Haem reversibly binds O with an affinity similar to that of the carotid body, suggesting that haem containing proteins may have a role in O, potentially this could be one of the complexes involved in oxidative-phosphorylation. This leads to increases in reactive oxygen species and rises in intracellular Ca. However, whether hypoxia leads to an increase or decrease in reactive oxygen species is unknown. The role of reactive oxygen species in hypoxia sensing is also under question. The oxygen dependent enzyme haem-oxidase has also