Pack animal Pack animal A pack animal or beast of burden is an individual or type of working animal used by humans as means of transporting materials by attaching them so their weight bears on the animal's back, in contrast to draft animals which pull loads but do not carry them. Traditional pack animals are diverse including camels, goats, yaks, reindeer, water buffaloes, and llamas as well as the more familiar pack animals like horses, donkeys and mules. The term "pack animal" is traditionally used in contrast to "draft animal", which is a working animal that typically pulls a load behind itself
Organ-on-a-chip it can facilitate cross-species extrapolation. Used in conjunction with PBPK models, the devices permit an estimation of effective concentrations that can be used for studies with animal models or predict the human response. In the development of multicompartment devices, representations of the human body such as those in used PBPK models can be used to guide the device design with regard to the arrangement of chambers and fluidic channel connections to augment the drug development process, resulting in increased success in clinical trials. Organ-on-a-chip An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics