Calyx of Held nervous system has allowed for direct research within a mammalian model and the large size increases the ease of electrophysiological recording. For these reasons it has been popular in understanding transmitter release. Specifically, the calyx of Held is used because of: Calyx of Held The Calyx of Held is a particularly large synapse in the mammalian auditory central nervous system, so named by Hans Held in his 1893 article "Die centrale Gehörleitung" because of its resemblance to the calyx of a flower. Globular bushy cells in the anteroventral cochlear nucleus (AVCN) send axons to the contralateral medial nucleus of the
History of botany publication of "papers" that emanated from research "schools" that promoted the questioning of conventional wisdom. This process had started in the late 18th century when specialist journals began to appear. Even so, botany was greatly stimulated by the appearance of the first "modern" textbook, Matthias Schleiden's (1804–1881) ', published in English in 1849 as "Principles of Scientific Botany". By 1850 an invigorated organic chemistry had revealed the structure of many plant constituents. Although the great era of plant classification had now passed the work of description continued. Augustin de Candolle (1778–1841) succeeded Antoine-Laurent de Jussieu in managing the botanical project