Calyx (anatomy) kidney, a conglomeration of two or three minor calyces to form a major calyx, or the Calyx of Held, a particularly large synapse in the mammalian auditory central nervous system, named by H. Held in his 1893 article "Die centrale Gehörleitung", due to its flower-petal-like shape. In male insects, a funnel-shaped expansion of the basal part of the "vas deferens" (part of the seminal duct). Also in entomology, a flattened cap of neuropile in an insect brain (a component of the corpus pedunculatum) and by certain female insects, an expansion of the oviduct into which the ovarioles open. Calyx (anatomy)
Calyx of Held causes an action potential to be triggered on the postsynaptic side – further encouraged by low internal sodium of the principal neurons. In the mature calyx, the AMPA receptors are concentrated on the principal neuron as to localize the transmission for greater action potential probability. Also note, the NMDA-type glutamate receptors contributions decrease after the onset of hearing. The mechanism behind synaptic vesicle endocytosis changes as the calyx becomes more mature. Calmodulin and calcineurin in their active form are required for vesicle endocytosis in an immature calyx; however, in the mature calyx neither calmodulin nor calcineurin are necessary. Rather, the