Carotid artery dissection Carotid artery dissection Carotid artery dissection is a separation of the layers of the artery wall supplying oxygen-bearing blood to the head and brain and is the most common cause of stroke in young adults. (In vascular medicine, dissection is a blister-like de-lamination between the outer and inner walls of a blood vessel, generally originating with a partial leak in the inner lining.) The signs and symptoms of carotid artery dissection may be divided into ischemic and non-ischemic categories: "Non-ischemic signs and symptoms" "Ischemic signs and symptoms" The causes of internal carotid artery dissection can be broadly categorised into two
Carotid body central chemoreceptors in the medulla oblongata that are primarily sensitive to changes in pH and P (a decrease in pH and an increase in P). The carotid body chemoreceptors are also sensitive to pH and P, but only secondarily. More specifically, the sensitivity of carotid body chemoreceptors to decreased P is greater when pH is decreased and P is increased. The output of the carotid bodies is low at an oxygen partial pressure above about 100mmHg (13,3 kPa) (at normal physiological pH), but below 60mmHg the activity of the type I (glomus) cells increases rapidly due to a decrease in