West Virginia per year, with 1,400 of those statistically attributed to deaths from heart, respiratory and kidney disease from living in an Appalachian coal county. In 2015, McDowell County had the highest rate of drug-induced deaths of any county in the United States, with a rate of 141 deaths per 100,000 people. Four of the five US counties with the highest rates of drug-induced deaths are located in West Virginia (McDowell, Wyoming, Cabell and Raleigh Counties). West Virginia's capital and seat of government is the city of Charleston, located in the southwest area of the state. The West Virginia Legislature is bicameral.
Virginia State Route 121 Virginia State Route 121 State Route 121 (SR 121) is a state highway in the U.S. state of Virginia. Known as Max Meadows Road, the state highway runs from Interstate 77, I-81, U.S. Route 11, and US 52 at Fort Chiswell north to SR 1004 and SR 1006 in Max Meadows in eastern Wythe County. SR 121 is part of a Virginia Byway that continues south along US 52 and west along SR 610 to Wytheville. SR 121 begins at a diamond interchange with I-77, I-81, and US 11 a short distance west of the interchange where I-77 turns south