Sistine Chapel ceiling picture is crowded with figures and separate incidents as the various individuals who have been attacked by snakes struggle and die or turn toward the icon that will save them. This is the most Mannerist of Michelangelo's earlier compositions at the Sistine Chapel, picking up the theme of human distress begun in the "Great Flood" scene and carrying it forward into the torment of lost souls in the "Last Judgement", which was later painted below. Between the large pendentives that support the vault are windows, six on each side of the chapel. There were two more windows in each end
Sistine Chapel ceiling to a strongly projecting painted cornice that runs right around the ceiling, separating the pictorial areas of the biblical scenes from the figures of Prophets, Sibyls, and Ancestors, who literally and figuratively support the narratives. Ten broad painted crossribs of travertine cross the ceiling and divide it into alternately wide and narrow pictorial spaces, a grid that gives all the figures their defined place. A great number of small figures are integrated with the painted architecture, their purpose apparently purely decorative. These include two faux marble "putti" below the cornice on each rib, each one a male and female pair;