West Virginia per year, with 1,400 of those statistically attributed to deaths from heart, respiratory and kidney disease from living in an Appalachian coal county. In 2015, McDowell County had the highest rate of drug-induced deaths of any county in the United States, with a rate of 141 deaths per 100,000 people. Four of the five US counties with the highest rates of drug-induced deaths are located in West Virginia (McDowell, Wyoming, Cabell and Raleigh Counties). West Virginia's capital and seat of government is the city of Charleston, located in the southwest area of the state. The West Virginia Legislature is bicameral.
Virginia State Route 144 and north as a continuation of Chester Road through an interchange with the SR 288 freeway. What would become SR 144 was first commissioned in 1930 as SR 425. It was significantly shorter than today's route, only running from State Route 407 in Chester to State Route 410 in Centralia. The route was given its current designation during the 1933 Virginia state highway renumbering. In 1943, it was extended west along SR 407 for a short length, then south to US 1 and US 301 using the routing of what was at the time State Route 621, a secondary road;