Sistine Chapel ceiling picture is crowded with figures and separate incidents as the various individuals who have been attacked by snakes struggle and die or turn toward the icon that will save them. This is the most Mannerist of Michelangelo's earlier compositions at the Sistine Chapel, picking up the theme of human distress begun in the "Great Flood" scene and carrying it forward into the torment of lost souls in the "Last Judgement", which was later painted below. Between the large pendentives that support the vault are windows, six on each side of the chapel. There were two more windows in each end
Restoration of the Sistine Chapel frescoes have been predicted by previous restorers. One of the major dangers to the frescoes is automotive exhaust, and they are also vulnerable to the effects of the crowds of tourists that pass through the chapel every day, bringing with them heat, humidity, dust and bacteria (the latter of which can biodegrade paints and pigments). The clean plaster surfaces are more in danger from these destructive elements than they were when they were covered with a layer of smoky wax. Previously, the Sistine Chapel's only ventilation was from its windows in the upper level of the walls. To prevent exhaust fumes