Calyx of Held nervous system has allowed for direct research within a mammalian model and the large size increases the ease of electrophysiological recording. For these reasons it has been popular in understanding transmitter release. Specifically, the calyx of Held is used because of: Calyx of Held The Calyx of Held is a particularly large synapse in the mammalian auditory central nervous system, so named by Hans Held in his 1893 article "Die centrale Gehörleitung" because of its resemblance to the calyx of a flower. Globular bushy cells in the anteroventral cochlear nucleus (AVCN) send axons to the contralateral medial nucleus of the
Discodermia calyx from it called calyculin A, which is a colorless oil used in a variety of different studies in modern medicine. "D. calyx" belongs to the Animalia family. Its phylum is "Porifera", which is characterizes it as a sponge. "D. calyx" belongs to the class demospongia and the order tetractinallida. The family that it belongs to is theonellida. Finally, the correct binomial nomenclature for this species of sponge is "Discodermia calyx", which indicates its genus and species. "D. calyx" has no colloquial name, as it is known primarily in scientific and medicinal contexts. "D. calyx" is one of a few sponges