Sistine Chapel ceiling picture is crowded with figures and separate incidents as the various individuals who have been attacked by snakes struggle and die or turn toward the icon that will save them. This is the most Mannerist of Michelangelo's earlier compositions at the Sistine Chapel, picking up the theme of human distress begun in the "Great Flood" scene and carrying it forward into the torment of lost souls in the "Last Judgement", which was later painted below. Between the large pendentives that support the vault are windows, six on each side of the chapel. There were two more windows in each end
Restoration of the Sistine Chapel frescoes watercolour, to integrate the pictorial material. These areas are distinctively textured with vertical brushstrokes, not visible from a distance but easily discernible as restoration work when viewed close up. Certain small areas were left unrestored, in order to maintain a physical record of the previous restorations that had taken place, for example, an area left with overpainting and candle wax, and another area demonstrating the attempt to counteract salination with oil. Once the many layers of candle wax, varnish, and animal glue were removed from the surface of the Sistine Chapel frescoes, they became subject to dangers that could not