Sistine Chapel ceiling picture is crowded with figures and separate incidents as the various individuals who have been attacked by snakes struggle and die or turn toward the icon that will save them. This is the most Mannerist of Michelangelo's earlier compositions at the Sistine Chapel, picking up the theme of human distress begun in the "Great Flood" scene and carrying it forward into the torment of lost souls in the "Last Judgement", which was later painted below. Between the large pendentives that support the vault are windows, six on each side of the chapel. There were two more windows in each end
Sistine Chapel ceiling "Life of Moses" on the left side. It was carried out by some of the most renowned Renaissance painters: Botticelli, Ghirlandaio, Perugino, Pinturicchio, Signorelli and Cosimo Rosselli. The upper level of the walls contains the windows, between which are painted pairs of illusionistic niches with representations of the first thirty-two popes. A draft by Matteo d'Amelia indicates that the ceiling was painted blue like that of the Arena Chapel and decorated with gold stars, possibly representing the zodiacal constellations. It is probable that, because the chapel was the site of regular meetings and Masses of an elite body of officials