Presidency of James Monroe knowledge of the northwest region of the Louisiana Purchase. The expedition suffered several setbacks, but the efforts of scientists such as Edwin James advanced U.S. knowledge of the flora and fauna of the region. The federal government had taken control of the Yazoo lands from Georgia in the Compact of 1802; as part of that agreement, President Jefferson promised to remove Native Americans from the region. Georgians pressed Monroe to remove the remaining Native Americans to regions west of the Mississippi River, but the Native Americans rejected the Monroe administration's offers to purchase their land. As Monroe was unwilling to
Monroe, Michigan Arbor-Flint combined statistical area, and the city is sometimes unofficially included as a northerly extension of the Toledo Metropolitan Area. The Monroe area saw several military conflicts during the War of 1812 with Great Britain and is best remembered for the Battle of Frenchtown. In 1817, portions of the Frenchtown settlement along the River Raisin were platted and renamed Monroe after then-president James Monroe. When Michigan became a state in 1837, Monroe was incorporated as a city. Monroe is known as the childhood residence of George Armstrong Custer and other members of his family, including his brother Boston Custer and