Silkie the "SHH" gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic "SHH" expression in the anterior of the developing limb bud, leading to increased tissue growth and digits. While the feet of the Silkie display polydactyly, the wings have the standard tridactyly (three digit) arrangement. The Japanese Silkie initially develops additional digits in the wing as an embryo, but these are lost prior to hatching. The genetic cause behind Silkie polydactyly differs from those that cause polydactyly in the Dorking chicken breed, which is due to ectopic "FGF4" expression in the AER, with ectopic "SHH" a secondary effect. The
The Silkie band Hapshash And The Coloured Coat. Ramsden received a kidney transplant in 1993, but prematurely died on 17 January 2004 in Totnes, Devon, at the age of 60, after a long battle with kidney disease. A retrospective sixteen-track album entitled You've Got To Hide Your Love Away was reissued on CD 30 years after the original group had disbanded in 1966. A track listing, together with brief audio samples, can be found here. * "You've Got to Hide Your Love Away" (click on the individual track song titles). The Silkie The Silkie were an English folk music group. Their name