Stringhalt management of Australian stringhalt. Two weeks after treatment with phenytoin, significant improvement was observed in the gait abnormality of horses affected with Australian stringhalt at the trot and canter, but no significant improvement was observed at the walk or while turning. The most common plant species that have been found and identified in pastures where affected horses were located include: flatweed ("Hypochaeris radicata"), sheep's sorrel ("Rumex acetosella") and couch grass ("Elymus repens"). The type of nerve damage sustained in horses with Australian stringhalt suggests a mould toxin (mycotoxin) or a fungal 'poison' found in the soils may be a cause
Central nervous system fatigue Central nervous system fatigue Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function. In healthy individuals, central fatigue can occur from prolonged exercise and is associated with neurochemical changes in the brain, primarily involving serotonin (5-HT), noradrenaline, and dopamine. Central fatigue plays an important role in endurance sports and also highlights the importance of proper nutrition