Silkie the "SHH" gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic "SHH" expression in the anterior of the developing limb bud, leading to increased tissue growth and digits. While the feet of the Silkie display polydactyly, the wings have the standard tridactyly (three digit) arrangement. The Japanese Silkie initially develops additional digits in the wing as an embryo, but these are lost prior to hatching. The genetic cause behind Silkie polydactyly differs from those that cause polydactyly in the Dorking chicken breed, which is due to ectopic "FGF4" expression in the AER, with ectopic "SHH" a secondary effect. The
Man Is Not a Bird Man Is Not a Bird Čovek nije tica (English title: Man Is Not a Bird) is a European art film made in 1965. It was the first film from director Dušan Makavejev. In a 1974 review, Vincent Canby described it "by far the most original, intelligent, witty and important film I've seen so far this year," and "the most sophisticated and complex film from a Communist country that I've ever seen." Highly skilled engineer Jan Rudinski (Janez Vrhovec) comes to a mining town to install new heavy equipment. While in a barber shop, he asks his pretty blond hairdresser Rajka