Sofía Cancino de Cuevas first quartet for strings, catalogued as Op. 1. In 1940, she received an honorable mention for her symphonic poem "El gallo en Pátzcuaro" for orchestra and male choir, in a contest organized by UNAM. In 1941 she directed the presentation of Mozart's "Don Giovanni" at the Arbeu theater, with the participation of singers (baritone), Carlos Mejía (tenor), and Margarita Cueto (soprano), among others. This made her Mexico's first female conductor. In 1944 she founded the Opera School, with which she conducted "La serva padrona" by Giovanni Battista Pergolesi, "Bastien und Bastienne" by Wolfgang Amadeus Mozart, and "Il matrimonio segreto" by
Vlatka Oršanić engaged as a soloist there and also began making guest appearances in other opera houses in what was then Yugoslavia. In that time she was celebrated as an extraordinary Lucia and Gilda. From 1985 to 1990 she lived in Vienna, where she pursued further study in solo singing techniques with Olivera Miljaković. The 1990s saw the beginning of Oršanić's international career. She sang at the Salzburg State Theatre where she appeared as Despina in "Così fan tutte", Bastienne in "Bastien und Bastienne", Euridice in "Orfeo ed Euridice" and Tamiri in "Il re pastore". She went on to sing as a