Pneumonia exposure to cigarettes or air pollution, malnutrition, and poverty. The use of acid-suppressing medications — such as proton-pump inhibitors or H2 blockers — is associated with an increased risk of pneumonia. Approximately 10% of people who require mechanical ventilation develop ventilator associated pneumonia, and people with gastric feeding tube have an increased risk of developing of aspiration pneumonia. For people with specific variants of FER gene, the risk of death is reduced in sepsis caused by pneumonia. However, for those with TLR6 variants, the risk of getting Legionnaires' disease is increased. Bacteria are the most-common cause of community-acquired pneumonia (CAP),
Pneumonia all deaths in those under five years, of which 95% occurred in the developing world. Countries with the greatest burden of disease include India (43 million), China (21 million) and Pakistan (10 million). It is the leading cause of death among children in low income countries. Many of these deaths occur in the newborn period. The World Health Organization estimates that one in three newborn infant deaths is due to pneumonia. Approximately half of these deaths can be prevented, as they are caused by the bacteria for which an effective vaccine is available. In 2011, pneumonia was the most common