Legionnaires' disease Legion convention in 1976 was high (29 deaths in 182 infected individuals) because the antibiotics used (including penicillins, cephalosporins, and aminoglycosides) had poor intracellular penetration. Mortality has plunged to less than 5% if therapy is started quickly. Delay in giving the appropriate antibiotic leads to higher mortality. The fatality rate of Legionnaires' disease has ranged from 5 to 30% during various outbreaks and approaches 50% for nosocomial infections, especially when treatment with antibiotics is delayed. Hospital-acquired "Legionella" pneumonia has a fatality rate of 28%, and the principal source of infection in such cases is the drinking-water distribution system. Legionnaires' disease
2018 Équateur province Ebola outbreak 2018), which was the most serious in the country since 1994. The table below indicates the 10 outbreaks that have occurred since 1976: 2018 Équateur province Ebola outbreak The 2018 Équateur province Ebola outbreak occurred in the north-west of the Democratic Republic of the Congo (DRC) from May to July 2018. It was the largest outbreak of Ebola virus disease (EVD) since the West African epidemic of 2013–16, but never spread beyond Équateur province. It was also the first time the rVSV-ZEBOV Ebola vaccine had been used to stop an outbreak, with a total of 3,481 people vaccinated. It was