New York City is the largest central business district in the world. Silicon Alley, centered in Manhattan, has evolved into a metonym for the sphere encompassing the New York City metropolitan region's high technology industries involving the Internet, new media, telecommunications, digital media, software development, biotechnology, game design, financial technology (""FinTech""), and other fields within information technology that are supported by its entrepreneurship ecosystem and venture capital investments. In 2015, Silicon Alley generated over US$7.3 billion in venture capital investment across a broad spectrum of high technology enterprises, most based in Manhattan, with others in Brooklyn, Queens, and elsewhere in the region. High
Science and technology in Israel voice-mail company; and Mercury Interactive, which measures software performance. A high concentration of high-tech industries in the coastal plain of Israel has led to the nickname Silicon Wadi (lit: "Silicon Valley"). Both Israeli and international companies are based there. Intel and Microsoft built their first overseas research and development centers in Israel, and other high-tech multi-national corporations, such as IBM, Cisco Systems, and Motorola, have opened facilities in the country. Intel developed its dual-core Core Duo processor at its Israel Development Center in Haifa. More than 3,850 start-ups have been established in Israel, making it second only to the US