1976 Philadelphia Legionnaires' disease outbreak 1976 Philadelphia Legionnaires' disease outbreak The 1976 Legionnaires disease outbreak, occurring in the late summer in Philadelphia, Pennsylvania, was the first occasion in which a cluster of a particular type of pneumonia cases were determined to be caused by the "Legionella pneumophila" bacteria. Previous outbreaks were retroactively diagnosed as being most probably caused by Legionella bacteria. On July 21, 1976, the American Legion opened its annual three-day convention at the Bellevue-Stratford Hotel in Philadelphia, Pennsylvania. More than 2,000 Legionnaires, mostly men, attended the convention. The date and city were chosen to coincide with America’s celebration of the 200th anniversary of
Hospital-acquired pneumonia inhibitors (piperacillin/tazobactam) Hospital-acquired pneumonia Hospital-acquired pneumonia (HAP) or nosocomial pneumonia refers to any pneumonia contracted by a patient in a hospital at least 48–72 hours after being admitted. It is thus distinguished from community-acquired pneumonia. It is usually caused by a bacterial infection, rather than a virus. HAP is the second most common nosocomial infection (after urinary tract infections) and accounts for 15–20% of the total. It is the most common cause of death among nosocomial infections and is the primary cause of death in intensive care units. HAP typically lengthens a hospital stay by 1–2 weeks. New or progressive