Cascade (juggling) and thrown from closer to the middle of the pattern, causing each ball to pass under the ball previously thrown, in a reverse cascade objects are caught near the middle of the pattern and thrown from the outside, causing each ball to pass above the ball previously thrown. Thus from the juggler's perspective the left hand moves in a clockwise motion, and the right hand in a counterclockwise motion. The reverse cascade is generally considered to be more difficult to perform than the cascade, with a difficulty rating of 4 rather than 2 out of 10. The reverse cascade is,
Cascade reaction them out. The efficiency and utility of a cascade reaction can be measured in terms of the number of bonds formed in the overall sequence, the degree of increase in the structural complexity via the process, and its applicability to broader classes of substrates. The earliest example of a cascade reaction is arguably the synthesis of tropinone reported in 1917 by Robinson. Since then, the use of cascade reactions has proliferated in the area of total synthesis. Similarly, the development of cascade-driven organic methodology has also grown tremendously. This increased interest in cascade sequences is reflected by the numerous relevant