Silkie the "SHH" gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic "SHH" expression in the anterior of the developing limb bud, leading to increased tissue growth and digits. While the feet of the Silkie display polydactyly, the wings have the standard tridactyly (three digit) arrangement. The Japanese Silkie initially develops additional digits in the wing as an embryo, but these are lost prior to hatching. The genetic cause behind Silkie polydactyly differs from those that cause polydactyly in the Dorking chicken breed, which is due to ectopic "FGF4" expression in the AER, with ectopic "SHH" a secondary effect. The
What Is a Man Without a Moustache? What Is a Man Without a Moustache? What Is a Man Without a Moustache? () is a 2005 Croatian romantic comedy-drama film. Hrvoje Hribar directed the film and wrote the screenplay as an adaptation of Ante Tomić's 2000 novel of the same name. Starring Leon Lučev and Zrinka Cvitešić and set against a background of a country still recovering from the Croatian War of Independence, the film tells the story of a young widow who falls in love with a local priest and a difficult choice that the priest faces when being forced to choose between the woman and his