Sofía Cancino de Cuevas first quartet for strings, catalogued as Op. 1. In 1940, she received an honorable mention for her symphonic poem "El gallo en Pátzcuaro" for orchestra and male choir, in a contest organized by UNAM. In 1941 she directed the presentation of Mozart's "Don Giovanni" at the Arbeu theater, with the participation of singers (baritone), Carlos Mejía (tenor), and Margarita Cueto (soprano), among others. This made her Mexico's first female conductor. In 1944 she founded the Opera School, with which she conducted "La serva padrona" by Giovanni Battista Pergolesi, "Bastien und Bastienne" by Wolfgang Amadeus Mozart, and "Il matrimonio segreto" by
Tristan und Isolde Tristan und Isolde Tristan und Isolde ("Tristan and Isolde", or "Tristan and Isolda", or "Tristran and Ysolt") is an opera, or music drama, in three acts by Richard Wagner to a German libretto by the composer, based largely on the 12th-century romance "Tristan" by Gottfried von Strassburg. It was composed between 1857 and 1859 and premiered at the Königliches Hof- und Nationaltheater in Munich on 10 June 1865 with Hans von Bülow conducting. Wagner referred to the work not as an opera, but called it "eine Handlung" (literally "a drama", "a plot" or "an action"), which was the equivalent of