Legionnaires' disease Legion convention in 1976 was high (29 deaths in 182 infected individuals) because the antibiotics used (including penicillins, cephalosporins, and aminoglycosides) had poor intracellular penetration. Mortality has plunged to less than 5% if therapy is started quickly. Delay in giving the appropriate antibiotic leads to higher mortality. The fatality rate of Legionnaires' disease has ranged from 5 to 30% during various outbreaks and approaches 50% for nosocomial infections, especially when treatment with antibiotics is delayed. Hospital-acquired "Legionella" pneumonia has a fatality rate of 28%, and the principal source of infection in such cases is the drinking-water distribution system. Legionnaires' disease
Epidemiology of pneumonia case fatality rate in the UK is around 5–10%. In the United States, community-acquired pneumonia affects 5.6 million people per year, and ranks 6th among leading causes of death. In 2009, there were approximately 1.86 million emergency department encounters for pneumonia in the United States. In 2011, pneumonia was the second-most common reason for hospitalization in the U.S., with approximately 1.1 million stays—a rate of 36 stays per 10,000 population. Pneumonia was one of the top ten most expensive conditions seen during inpatient hospitalizations in the U.S. in 2011, with an aggregate cost of nearly $10.6 billion for 1.1 million