Silkie the "SHH" gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic "SHH" expression in the anterior of the developing limb bud, leading to increased tissue growth and digits. While the feet of the Silkie display polydactyly, the wings have the standard tridactyly (three digit) arrangement. The Japanese Silkie initially develops additional digits in the wing as an embryo, but these are lost prior to hatching. The genetic cause behind Silkie polydactyly differs from those that cause polydactyly in the Dorking chicken breed, which is due to ectopic "FGF4" expression in the AER, with ectopic "SHH" a secondary effect. The
What Is a Rumpletilskin? What Is a Rumpletilskin? What Is a Rumpletilskin? is the first and only album by hip hop group Rumpletilskinz, released on July 13, 1993, on RCA Records and produced by the group's producer, R.P.M. The album failed to make it to any of the "Billboard" charts, but two singles did, "Attitudes" and "Is It All Right?" Both made it to #24 on the Hot Rap Singles. This release received extensive national independent retail promotion through Poindexter International Marketing & Promotions, which was employed by RCA Records. It was also one of the first projects managed by James "DJ Ras J"