Silkie the "SHH" gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic "SHH" expression in the anterior of the developing limb bud, leading to increased tissue growth and digits. While the feet of the Silkie display polydactyly, the wings have the standard tridactyly (three digit) arrangement. The Japanese Silkie initially develops additional digits in the wing as an embryo, but these are lost prior to hatching. The genetic cause behind Silkie polydactyly differs from those that cause polydactyly in the Dorking chicken breed, which is due to ectopic "FGF4" expression in the AER, with ectopic "SHH" a secondary effect. The
The Silkie The Silkie The Silkie were an English folk music group. Their name was derived from an Orcadian song "The Great Silkie of Sule Skerry", which they sometimes performed. They were briefly considered to be the English equivalent of Peter, Paul and Mary, with their common repertoire of Bob Dylan songs, and the original Australian folk group, The Seekers. The four original members were all Hull University students who formed the group in October 1963. It consisted of Sylvia Tatler (vocals) (born 1945, Stoke-on-Trent, Staffordshire), Mike Ramsden (guitar and vocals) (born Michael John Ramsden, 21 June 1943, Totnes, Devon), Ivor Aylesbury