FNB Stadium is home to Kaizer Chiefs Football Club. It is also the preferred venue for the Soweto derby football matches - the country's biggest sporting showpiece - involving Soweto based Premier Soccer League clubs, Kaizer Chiefs and Orlando Pirates. It was also the traditional home of the Iwisa Maize Meal Spectacular and later, the Telkom Charity Cup, which were charity soccer season openers in South African football from 1990 to 2006, before it was closed for renovations. The Charity Cup then returned in 2010. The stadium was re-opened when it hosted the 2010 Nedbank Cup final between Bidvest Wits and Amazulu.
1999–2000 Premier Soccer League record they jointly set with Kaizer Chiefs last season, but unlike the previous season in which the title was decided by goal difference, there was no close title race this season as Sundowns finished comfortably ahead of second placed Orlando Pirates with an 11-point margin. As before, the league was contested by 18 teams, sixteen returning from the 1997–98 season and two newly promoted clubs; the returning African Wanderers and Tembisa Classic. The league continued to run parallel to the European football calendar (August–May) and not run concurrently with the African football calendar (January–December). Mamelodi Sundowns clinched a record third