Opera After Verdi, the sentimental "realistic" melodrama of verismo appeared in Italy. This was a style introduced by Pietro Mascagni's "Cavalleria rusticana" and Ruggero Leoncavallo's "Pagliacci" that came to dominate the world's opera stages with such popular works as Giacomo Puccini's "La bohème", "Tosca", and "Madama Butterfly". Later Italian composers, such as Berio and Nono, have experimented with modernism. The first German opera was "Dafne", composed by Heinrich Schütz in 1627, but the music score has not survived. Italian opera held a great sway over German-speaking countries until the late 18th century. Nevertheless, native forms would develop in spite of this
Diseases and epidemics of the 19th century Diseases and epidemics of the 19th century Diseases and epidemics of the 19th century reached epidemic proportions in the case of one emerging infectious disease: cholera. Other important diseases at that time in Europe and other regions included smallpox, typhus and yellow fewer. Epidemics of the 19th century were faced without the medical advances that made 20th-century epidemics much more rare and less lethal. Micro-organisms (viruses and bacteria) had been discovered in the 18th century, but it was not until the late 19th century that the experiments of Lazzaro Spallanzani and Louis Pasteur disproved spontaneous generation conclusively, allowing germ theory