Silkie the "SHH" gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic "SHH" expression in the anterior of the developing limb bud, leading to increased tissue growth and digits. While the feet of the Silkie display polydactyly, the wings have the standard tridactyly (three digit) arrangement. The Japanese Silkie initially develops additional digits in the wing as an embryo, but these are lost prior to hatching. The genetic cause behind Silkie polydactyly differs from those that cause polydactyly in the Dorking chicken breed, which is due to ectopic "FGF4" expression in the AER, with ectopic "SHH" a secondary effect. The
Dark Bird Is Home Dark Bird Is Home Dark Bird Is Home is the fourth LP by The Tallest Man on Earth. It was released on CD, digital and vinyl on May 12, 2015 through the label Dead Oceans. The album is the first in his discography to feature a full band playing on almost every track. The songs of the album were recorded in various countries, studios, and barns, and are said to "carry a weather-worn quality, some dirt and some grit." BJ Burton announced via his Instagram page that production on the album had begun in July 2014 and concluded in September