Stringhalt management of Australian stringhalt. Two weeks after treatment with phenytoin, significant improvement was observed in the gait abnormality of horses affected with Australian stringhalt at the trot and canter, but no significant improvement was observed at the walk or while turning. The most common plant species that have been found and identified in pastures where affected horses were located include: flatweed ("Hypochaeris radicata"), sheep's sorrel ("Rumex acetosella") and couch grass ("Elymus repens"). The type of nerve damage sustained in horses with Australian stringhalt suggests a mould toxin (mycotoxin) or a fungal 'poison' found in the soils may be a cause
Animal model of schizophrenia a growth factor which is crucial to the development of the nervous system, and to neurotransmission and formation of synapses in adults. NRG1 and the gene for the receptor to which neuregulin 1 binds, ERBB4, have been tested as possible animal models of schizophrenia. While mice which have two copies of (are homozygous for) a knocked out version of NRG1 do not survive, viable animal models have been developed using heterozygous or partial knockout. One such mouse model is the heterozygous removal of the EGF-like domain on neuregulin 1, these models are called Nrg1(ΔEGF) mice. Nrg1(ΔEGF) mice have been shown