New York (state) States, while Midtown Manhattan is the largest central business district in the nation. Silicon Alley, centered in New York City, has evolved into a metonym for the sphere encompassing the New York City metropolitan region's high technology and entrepreneurship ecosystem; in 2015, Silicon Alley generated over US$7.3 billion in venture capital investment. High tech industries including digital media, biotechnology, software development, game design, and other fields in information technology are growing, bolstered by New York City's position at the terminus of several transatlantic fiber optic trunk lines, its intellectual capital, as well as its growing outdoor wireless connectivity. In December
Silicon Wadi 2010, more than 35,000 personnel were employed in multinationals research and development centers across Israel. In recent years, East Asian multinationals and investors, especially from Mainland China, have actively invested and opened up offices in Israel, including Chinese technology giants such as Alibaba, Baidu, Tencent and Kuang-Chi. Around 60 foreign R&D centers are engaged in a diverse range of activities including biotechnology, chemicals, industrial machinery, communication equipment, scientific instruments, medical devices, flash memory storage equipment, computer hardware components, software, semiconductors and internet. Silicon Wadi Silicon Wadi (, lit: "Silicon Valley") is an area with a high concentration of high-technology companies