Silkie the "SHH" gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic "SHH" expression in the anterior of the developing limb bud, leading to increased tissue growth and digits. While the feet of the Silkie display polydactyly, the wings have the standard tridactyly (three digit) arrangement. The Japanese Silkie initially develops additional digits in the wing as an embryo, but these are lost prior to hatching. The genetic cause behind Silkie polydactyly differs from those that cause polydactyly in the Dorking chicken breed, which is due to ectopic "FGF4" expression in the AER, with ectopic "SHH" a secondary effect. The
Man Is Not a Bird has succumbed to the charms of the truck driver. Jan asks her afterward if she has another lover. When she is evasive, he asks how old his rival is; she answers 20 or 22, but claims it does not matter to their relationship. This does not appease his anger, and she flees. Man Is Not a Bird Čovek nije tica (English title: Man Is Not a Bird) is a European art film made in 1965. It was the first film from director Dušan Makavejev. In a 1974 review, Vincent Canby described it "by far the most original, intelligent, witty and