Silkie the "SHH" gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic "SHH" expression in the anterior of the developing limb bud, leading to increased tissue growth and digits. While the feet of the Silkie display polydactyly, the wings have the standard tridactyly (three digit) arrangement. The Japanese Silkie initially develops additional digits in the wing as an embryo, but these are lost prior to hatching. The genetic cause behind Silkie polydactyly differs from those that cause polydactyly in the Dorking chicken breed, which is due to ectopic "FGF4" expression in the AER, with ectopic "SHH" a secondary effect. The
What Is a Nation? to the reasons based on race, geography, history and so on. They argue that Renan maintains his intellectual background but subtly, i.e. the arguments he explicitly used in "What is a Nation?" are not consistent with his thinking. The concept of "daily plebiscite" would be ambiguous. They argue that the definition is an opportunist idealization and it should be interpreted within the Franco-Prussian War and in the midst of the dispute concerning the Alsace-Lorraine region. What Is a Nation? "What is a Nation?" ("Qu'est-ce qu'une nation?") is an 1882 lecture by French historian Ernest Renan (1823–1892), known for the statements