FNB Stadium is home to Kaizer Chiefs Football Club. It is also the preferred venue for the Soweto derby football matches - the country's biggest sporting showpiece - involving Soweto based Premier Soccer League clubs, Kaizer Chiefs and Orlando Pirates. It was also the traditional home of the Iwisa Maize Meal Spectacular and later, the Telkom Charity Cup, which were charity soccer season openers in South African football from 1990 to 2006, before it was closed for renovations. The Charity Cup then returned in 2010. The stadium was re-opened when it hosted the 2010 Nedbank Cup final between Bidvest Wits and Amazulu.
Kaizer Chiefs F.C. Provincial Government have agreed to develop the needed infrastructures around the stadium, in order to guarantee sufficient road and railway access for the huge crowd of spectators. The stadium developers initially had set time lines for the Amakhosi stadium, to open its doors for the public in December 2008. As of July 2010, construction however had not yet started. Kaizer Chiefs announced in August 2010, that construction of Amakhosi Stadium was now expected only to start in autumn 2010, and finalised by August 2012. It had been postponed several years, due to Kaizer Chiefs and its joint partners, facing difficulties