Silkie the "SHH" gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic "SHH" expression in the anterior of the developing limb bud, leading to increased tissue growth and digits. While the feet of the Silkie display polydactyly, the wings have the standard tridactyly (three digit) arrangement. The Japanese Silkie initially develops additional digits in the wing as an embryo, but these are lost prior to hatching. The genetic cause behind Silkie polydactyly differs from those that cause polydactyly in the Dorking chicken breed, which is due to ectopic "FGF4" expression in the AER, with ectopic "SHH" a secondary effect. The
What the Little Bird Told Him thirteenth and final episode of the season. Gotham, originally scheduled for 16 episodes, still has 10 more to go though, and it’s unclear how the show is going to be able to sustain the (very) slight momentum this episode built." What the Little Bird Told Him "What the Little Bird Told Him" is the twelfth episode of the television series "Gotham". It premiered on FOX on January 19, 2015 and was written by Ben Edlund, and directed by Eagle Egilsson. In this episode, Gordon (Ben McKenzie) looks to capture a prisoner who escaped from Arkham Asylum to get his job