Pneumonia exposure to cigarettes or air pollution, malnutrition, and poverty. The use of acid-suppressing medications — such as proton-pump inhibitors or H2 blockers — is associated with an increased risk of pneumonia. Approximately 10% of people who require mechanical ventilation develop ventilator associated pneumonia, and people with gastric feeding tube have an increased risk of developing of aspiration pneumonia. For people with specific variants of FER gene, the risk of death is reduced in sepsis caused by pneumonia. However, for those with TLR6 variants, the risk of getting Legionnaires' disease is increased. Bacteria are the most-common cause of community-acquired pneumonia (CAP),
Pneumonia adults began in 1977, and in children in 2000, resulting in a similar decline. Due to the relatively low awareness of the disease, 12 November was declared as the annual World Pneumonia Day, a day for concerned citizens and policy makers to take action against the disease, in 2009. The global economic cost of community-acquired pneumonia has been estimated at $17 billion annually. Other estimates are considerably higher. In 2012 the estimated aggregate costs of treating pneumonia in the United States were $20 billion; the median cost of a single pneumonia-related hospitalization is over $15,000. According to data released by