Legionnaires' disease Legion convention in 1976 was high (29 deaths in 182 infected individuals) because the antibiotics used (including penicillins, cephalosporins, and aminoglycosides) had poor intracellular penetration. Mortality has plunged to less than 5% if therapy is started quickly. Delay in giving the appropriate antibiotic leads to higher mortality. The fatality rate of Legionnaires' disease has ranged from 5 to 30% during various outbreaks and approaches 50% for nosocomial infections, especially when treatment with antibiotics is delayed. Hospital-acquired "Legionella" pneumonia has a fatality rate of 28%, and the principal source of infection in such cases is the drinking-water distribution system. Legionnaires' disease
Epidemiology of pneumonia of age. It occurs about five times more frequently in the developing world versus the developed world. Viral pneumonia accounts for about 200 million cases. Hospital-acquired pneumonia is pneumonia that is acquired in a hospital setting at least 48 hours after being admitted. Pneumonia the second most common hospital-acquired disease, while also being the leading cause of death among hospital-acquired infections. Hospital-acquired pneumonia is also seen to be the cause for nearly half of all the antibiotics taken within hospitals worldwide. A sub-type of hospital-acquired pneumonia, known as ventilator-associated pneumonia, is described as pneumonia acquired more than 48 hours after