Coenzyme Q10 be measured in blood plasma, these measurements reflect dietary intake rather than tissue status. Currently, most clinical centers measure CoQ levels in cultured skin fibroblasts, muscle biopsies, and blood mononuclear cells. Culture fibroblasts can be used also to evaluate the rate of endogenous CoQ biosynthesis, by measuring the uptake of C-labelled "p"-hydroxybenzoate. CoQ shares a biosynthetic pathway with cholesterol. The synthesis of an intermediary precursor of CoQ, mevalonate, is inhibited by some beta blockers, blood pressure-lowering medication, and statins, a class of cholesterol-lowering drugs. Statins can reduce serum levels of CoQ by up to 40%. CoQ is not approved by
Blood bike Blood bike A blood bike is a motorcycle used to courier urgent and emergency medical items including blood, X-rays, samples, drugs, and documentation between hospitals and other healthcare facilities. In the United Kingdom and Ireland a network of largely independent registered charities, whose members are all unpaid volunteers, provide blood bike courier services in collaboration with their local healthcare authorities. Many are represented through the Nationwide Association of Blood Bikes (NABB). Commercial blood bike courier services also exist. The first blood bike volunteer group to be established was the Emergency Volunteer Service (EVS), formed in 1962 in Surrey, England, by