Malaria saved the lives of thousands of workers and helped develop the methods used in future public-health campaigns against the disease. The first effective treatment for malaria came from the bark of cinchona tree, which contains quinine. This tree grows on the slopes of the Andes, mainly in Peru. The indigenous peoples of Peru made a tincture of cinchona to control fever. Its effectiveness against malaria was found and the Jesuits introduced the treatment to Europe around 1640; by 1677, it was included in the London Pharmacopoeia as an antimalarial treatment. It was not until 1820 that the active ingredient, quinine,
Hugh Algernon Weddell des environs de Paris (1845). In 1843, he was invited to join the expedition of François Louis de la Porte, comte de Castelnau to South America, and he explored and collected botanical specimens on that continent for five years. In May 1845, Weddell left the expedition which was then in Paraguay, and proceeded on a solitary journey which would take him into Peru and Bolivia. Before leaving Paris, he had been particularly instructed by the Muséum national d'Histoire naturelle to undertake a thorough investigation of the "Cinchona" plant, or "fever bark" tree in its native habitat. "Cinchona", the source of