Pleiotropy (drugs) Pleiotropy (drugs) In pharmacology, pleiotropy includes all of a drug's actions other than those for which the agent was specifically developed. It may include adverse effects which are detrimental ones, but is often used to denote additional beneficial effects. For example, statins are HMG-CoA reductase inhibitors that primarily act by decreasing cholesterol synthesis, but which are believed to have other beneficial effects, including acting as antioxidants and stabilizing atherosclerotic plaques. Steroid drugs, such as prednisone and prednisolone, have pleiotropic effects, including systemic ones, for the same reason that endogenous steroid hormones do too: cells throughout the body have receptors that
We Are All on Drugs We Are All on Drugs "We Are All on Drugs" is a song by American alternative rock band Weezer. It was released as the second single from the band's 2005 album, "Make Believe". "We Are All on Drugs" was released to radio on July 12, 2005. The song is not specifically about drugs. Rather, Rivers Cuomo has said that it is more generally about the over-stimulated society addicted to the internet, gambling, drugs and relationships. The song went into mixing with two lines in the bridge:, "I want to confiscate your drugs/ I don't think I can get enough", and