Quinine London. It remained the antimalarial drug of choice until the 1940s, when other drugs took over. The form of quinine most effective in treating malaria was found by Charles Marie de La Condamine in 1737. In 1820, French researchers Pierre Joseph Pelletier and Joseph Bienaimé Caventou first isolated quinine from the bark of a tree in the genus "Cinchona" - probably "Cinchona officinalis" - and subsequently named the substance. The name was derived from the original Quechua (Inca) word for the cinchona tree bark, "quina" or "quina-quina", which means "bark of bark" or "holy bark". Prior to 1820, the bark
Bark painting from Stringybark ("Eucalyptus tetradonta"). The bark must be free of knots and other blemishes. It is best cut from the tree in the wet season when the sap is rising. Two horizontal slices and a single vertical slice are made into the tree, and the bark is carefully peeled off with the aid of a sharpened tool. Only the inner smooth bark is kept and placed in a fire. After heating in the fire, the bark is flattened under foot and weighted with stones or logs to dry flat. Once dry, it is ready to paint upon. Earth pigments—or ochres—in