Statin either the LDL receptor or apolipoprotein B genes, both of which are responsible for LDL clearance from the blood. Statins remain a first-line treatment in familial hypercholesterolemia, although other cholesterol-reducing measures may be required. In people with homozygous deficiencies, statins may still prove helpful, albeit at high doses and in combination with other cholesterol-reducing medications. A 2014 meta-analysis found that statins could reduce the risk of contrast-induced nephropathy by 53% in people undergoing coronary angiography/percutaneous interventions. The effect was found to be stronger among those with preexisting kidney dysfunction or diabetes mellitus. The most important adverse side effects are muscle
We Are Drugs The band focused on continuous sessions that would take a song from conception to completion. No guidelines or definitions of what the music should be or sound like were permitted during the sessions; this allowed the band to create the music they felt in the time they were working on it. Lyrics and vocals for the track "Weightless," however, were completed outside of the initial sessions: Jenkins didn't complete either until September 13, 2016—only three weeks before the EP was released. Jenkins states that the EP's name is meant to tie into their preceding album "Dopamine", with drugs being something