Quinine the Quechua, who are indigenous to Peru, Bolivia and Ecuador, to halt shivering due to low temperatures. The Quechuas would mix the ground bark of cinchona trees with sweetened water to offset the bark's bitter taste, thus producing tonic water. The Jesuits were the first to bring cinchona to Europe. The Spanish were aware of the medicinal properties of cinchona bark by the 1570s or earlier: Nicolás Monardes (1571) and Juan Fragoso (1572) both described a tree that was subsequently identified as the cinchona tree and whose bark was used to produce a drink to treat diarrhea. Quinine has been
Bark! The Musical Bark! The Musical BARK! The Musical is a musical with music by David Troy Francis and lyrics by Gavin Geoffrey Dillard and Robert Schrock (with additional lyrics by Mark Winkler). The book is by Mark Winkler and Gavin Geoffrey Dillard. "BARK!" explores one day in the lives of six dogs in Deena's Doggie Daycare. These dogs include a little puppy who yearns to bark like a real dog, an opera singing poodle, and a street mutt who raps and sometimes cross dresses as a chihuahua. The entire show is presented from a dog’s point of view. "BARK!" made its world