Consumer Reports Best Buy Drugs category; and cost less on average than other drugs in the category. Several of the Best Buys have been chosen because of their superior effectiveness or safety profile even though they may cost more. The project publishes Best Buy Drugs drug reports, the first three such reports covered Statins to reduce high cholesterol, heartburn drugs, and NSAIDs commonly used to treat arthritis. The project covers over 20 conditions and the most widely used drugs. The reports are published in web versions, and two-page PDF summaries in English and Spanish. More than half of all prescription drugs cause adverse effects—some serious
Fluvastatin Fluvastatin Fluvastatin (INN, trade names Lescol, Canef, Vastin) is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease. Adverse effects are comparable to other statins. Common are nausea, indigestion, insomnia and headache. Myalgia (muscle pain), and rarely rhabdomyolysis, characteristic side effects for statins, can also occur. Contrary to lovastatin, simvastatin and atorvastatin, fluvastatin has no relevant interactions with drugs that inhibit the liver enzyme CYP3A4, and a generally lower potential for interactions than most other statins. Fluconazole, a potent inhibitor of CYP2C9, does increase fluvastatin levels. Fluvastatin works by blocking the liver enzyme