Cinchona pubescens hence its nickname the red quinine tree. Its flowers form in large panicles. They are pink and fragrant, while in the Galapagos they are light pink. "C. pubescens" has the widest distribution of all "Cinchona" species, with the native range spanning Costa Rica, Panama, Venezuela, Colombia, Ecuador, Peru, and Bolivia. In Ecuador it is distributed within an altitude from . It also grows well in volcanic soil with high nutrient levels. C. pubescens is a resilient species that is able to recover from even extreme damage. If the tree is felled but the stump is left, it can grow back
Analgesic nephropathy between the 1960s and 1980s. As the use of phenacetin declined, so too did the prevalence of analgesic nephropathy as a cause of end-stage kidney disease. Data from Switzerland, for example, demonstrated a decline in the prevalence of analgesic nephropathy among people with end-stage kidney disease, from 28% in 1981 to 12% in 1990. An autopsy study performed in Switzerland suggested that the prevalence of analgesic nephropathy in the general population has likewise decreased; the prevalence was 3% in 1980 and 0.2% in 2000. While these data demonstrate that analgesic nephropathy has been all but eliminated in some regions, in