Cinchona for quinine production. While ultimately successful in their primary aim, these expeditions also identified new species of plants and created a new chapter in international relations between the United States and other nations in the Americas. Francesco Torti used the response of fevers to treatment with cinchona as a system of classification of fevers or a means for diagnosis. The use of cinchona in the effective treatment of malaria brought an end to treatment by bloodletting and long-held ideas of humorism from Galen. For his part in obtaining and helping the establishment of cinchona in British India Clements Markham was
Hugh Algernon Weddell des environs de Paris (1845). In 1843, he was invited to join the expedition of François Louis de la Porte, comte de Castelnau to South America, and he explored and collected botanical specimens on that continent for five years. In May 1845, Weddell left the expedition which was then in Paraguay, and proceeded on a solitary journey which would take him into Peru and Bolivia. Before leaving Paris, he had been particularly instructed by the Muséum national d'Histoire naturelle to undertake a thorough investigation of the "Cinchona" plant, or "fever bark" tree in its native habitat. "Cinchona", the source of