Cinchona lost their plants when a wave took them off their ship. The Dutch sent Justus Hasskarl who brought plants that were then cultivated in Java from 1854. The English explorer Clements Markham went to collect plants that were introduced in Sri Lanka and the Nilgiris of southern India in 1860. The main species introduced were "Cinchona succirubra" or red bark, as its sap turned red on contact with air, and "Cinchona calisaya". The alkaloids quinine and cinchonine were extracted by Pelletier and Caventou in 1820. Later two more key alkaloids, quinidine and cinchonidine were identified and it became a routine
Tree fork forms in a tree and bark is incorporated into the join, this is referred to as an 'included bark junction' or 'bark inclusion'. A common cause of bark being incorporated into the junction is that the junction is braced by the touching of branches or stems set above that junction (in arboriculture, these branch interactions are termed 'natural braces'). Such included bark junctions can be substantially weaker in strength than normal tree forks, and can become a significant hazard in a tree, particularly when the bracing branches are shaded out or pruned out of the tree. Research has shown that