Quinine the Quechua, who are indigenous to Peru, Bolivia and Ecuador, to halt shivering due to low temperatures. The Quechuas would mix the ground bark of cinchona trees with sweetened water to offset the bark's bitter taste, thus producing tonic water. The Jesuits were the first to bring cinchona to Europe. The Spanish were aware of the medicinal properties of cinchona bark by the 1570s or earlier: Nicolás Monardes (1571) and Juan Fragoso (1572) both described a tree that was subsequently identified as the cinchona tree and whose bark was used to produce a drink to treat diarrhea. Quinine has been
Bark beetle economic impact. In undisturbed forests, bark beetles serve the purpose of hastening the recycling and decomposition of dead and dying wood and renewing the forest. A few species are aggressive and can develop large populations that invade and kill healthy trees and are therefore known as pests. Bark beetles of the family Scolytidae feed and breed between the bark and the wood of various tree species, including spruces. More than 20 species feed on weakened, dying, or dead spruce, fir, and hemlock. Most restrict breeding area to one part of the tree: twig, branch, stem, or root collar. Some breed