Statin either the LDL receptor or apolipoprotein B genes, both of which are responsible for LDL clearance from the blood. Statins remain a first-line treatment in familial hypercholesterolemia, although other cholesterol-reducing measures may be required. In people with homozygous deficiencies, statins may still prove helpful, albeit at high doses and in combination with other cholesterol-reducing medications. A 2014 meta-analysis found that statins could reduce the risk of contrast-induced nephropathy by 53% in people undergoing coronary angiography/percutaneous interventions. The effect was found to be stronger among those with preexisting kidney dysfunction or diabetes mellitus. The most important adverse side effects are muscle
What Are The Theosophists? often attracted all sorts of neurotics, hysterics and even madmen: "All organisations which depend on enthusiasm and opposition to conventional opinion suffer from this problem to some degree; Theosophy appears to have been especially prone to it. The permanent residents at Adyar during the 1880s and '90s were typical. A quarrelsome collection of minor English aristocrats, rich American widows, German professors, Indian mystics and hangerson of every description, they were all eager to have their say, especially during Olcott's prolonged absences, and all ready to quarrel with one another." What Are The Theosophists? "What Are The Theosophists?" is an editorial