Edward Stone (natural philosopher) piece of bark from a willow tree and was struck by its extremely bitter taste. Knowing that the bark of the Peruvian cinchona tree − from which quinine (used in the treatment of malarial fevers) is derived − has a similarly bitter taste, he surmised that the willow might also have therapeutic properties. Stone's interest in willows was due to the ancient "doctrine of signatures" – whereby the cause of a disease offers a clue to its treatment. According to Stone: "As this tree delights in a moist or wet soil, where agues chiefly abound, the general maxim that many
Quercus leucotrichophora to October. Naturally, it regenerates via seeds. "Quercus leucotrichophora" is distributed in Northern India, Nepal, Myanmar, Pakistan, and Sri Lanka. In Nepal, it naturally occurs at 1500–2700 m in forested areas in association with "Rhododendron arboreum". In the Himalayas, "Quercus leucotrichophora" is lopped for fodder from December to June. Its wood is used in building purposes and as a good fuel. The acorns are edible, and the seeds can be roasted to make a coffee substitute. "Quercus leucotrichophora" also has uses in ethnomedicine, the gum being used for treating colds and as an analgesic. The tree is affected with many