Pleiotropy (drugs) Pleiotropy (drugs) In pharmacology, pleiotropy includes all of a drug's actions other than those for which the agent was specifically developed. It may include adverse effects which are detrimental ones, but is often used to denote additional beneficial effects. For example, statins are HMG-CoA reductase inhibitors that primarily act by decreasing cholesterol synthesis, but which are believed to have other beneficial effects, including acting as antioxidants and stabilizing atherosclerotic plaques. Steroid drugs, such as prednisone and prednisolone, have pleiotropic effects, including systemic ones, for the same reason that endogenous steroid hormones do too: cells throughout the body have receptors that
We Are Drugs The band focused on continuous sessions that would take a song from conception to completion. No guidelines or definitions of what the music should be or sound like were permitted during the sessions; this allowed the band to create the music they felt in the time they were working on it. Lyrics and vocals for the track "Weightless," however, were completed outside of the initial sessions: Jenkins didn't complete either until September 13, 2016—only three weeks before the EP was released. Jenkins states that the EP's name is meant to tie into their preceding album "Dopamine", with drugs being something