Lanosterol synthase disease prevention and treatment (see Disease Relevance, below). Interest has grown in lanosterol synthase inhibitors as drugs to lower blood cholesterol and treat atherosclerosis. The widely popular statin drugs currently used to lower LDL (low-density lipoprotein) cholesterol function by inhibiting HMG-CoA reductase activity. Because this enzyme catalyzes the formation of precursors far upstream of (S)-2,3-epoxysqualene and cholesterol, statins may negatively influence amounts of intermediates required for other biosynthetic pathways (e.g. synthesis of isoprenoids, coenzyme Q). Thus, lanosterol synthase, which is more closely tied to cholesterol biosynthesis than HMG-CoA reductase, is an attractive drug target. Lanosterol synthase inhibitors are thought to
We Are Drugs Are Drugs", was released for streaming on September 8, 2016. The band played the 2016 iteration of Lollapalooza to promote the EP as well. We Are Drugs We Are Drugs is a studio EP by American alternative rock band Third Eye Blind. Preceded by the release of the single "Cop vs. Phone Girl" on July 25, 2016, "We Are Drugs" was published on October 7, 2016. As early as 2012, Third Eye Blind frontman Stephan Jenkins stated that following the release of their fifth album, they would cease releasing full albums, in favor of smaller EP releases. After the band