Statin either the LDL receptor or apolipoprotein B genes, both of which are responsible for LDL clearance from the blood. Statins remain a first-line treatment in familial hypercholesterolemia, although other cholesterol-reducing measures may be required. In people with homozygous deficiencies, statins may still prove helpful, albeit at high doses and in combination with other cholesterol-reducing medications. A 2014 meta-analysis found that statins could reduce the risk of contrast-induced nephropathy by 53% in people undergoing coronary angiography/percutaneous interventions. The effect was found to be stronger among those with preexisting kidney dysfunction or diabetes mellitus. The most important adverse side effects are muscle
The Young Blood Chronicles a parking lot, Joe at a gas station and Pete on a rooftop. The Vixens bring Pete, Andy and Joe to a dinner table, at which Patrick is already seated. They are strapped to chairs and hooked to intravenous drips. They are served blood wine, hookahs and snuffable colored powder resembling cocaine. The women then serve them cobbler, fruit and Patrick's organs. The drugs make them believe they are dancing with their captors and naked women wearing bloody animal masks, yet are left still bound to their chairs. The briefcase is delivered to a vehicle with the license plate "RATATAT".