Psittacosis known serovars. All should be considered to be readily transmissible to humans. "C. psittaci" serovar A is endemic among psittacine birds and has caused sporadic zoonotic disease in humans, other mammals, and tortoises. Serovar B is endemic among pigeons, has been isolated from turkeys, and has also been identified as the cause of abortion in a dairy herd. Serovars C and D are occupational hazards for slaughterhouse workers and for people in contact with birds. Serovar E isolates (known as Cal-10, MP, or MN) have been obtained from a variety of avian hosts worldwide, and although they were associated with
Kufs disease one copy of the mutation, however the recessive designation indicates that with only one copy, the parents are not affected, and do not show any symptoms. Kufs disease Type B is caused by mutations to the DNAJC5 and CTSF genes. This form of Kufs is autosomal dominant, meaning that only one copy of each mutated gene is enough for the disease to manifest. When there is a mutation in the DNAJC5 gene, it affects the production of a cysteine string protein (CSP) that is coded within DNAJC5. CSP aids in transmitting signals through the nerves found in the brain. When