Discovery and development of statins trials showed very good inhibitory effect as in clinical trials, however in a long term toxicity study in dogs it resulted in toxic effects at higher doses and as a result was believed to be too toxic to be given to humans. In 1978, Alfred Alberts and colleagues at Merck Research Laboratories discovered a new natural product in a fermentation broth of "Aspergillus terreus", their product showed good HMGR inhibition and they named the product mevinolin, which later became known as lovastatin. The cholesterol controversy began in the early promotion of statins. Statins are a competitive antagonists of HMG CoA,
What Degree? Which University? their studying experiences. Handley resurrected the concept in 2010 with the help of a team of undergraduate students, and launched "What Degree? Which University?" as a website in August 2011. Six months after its launch, "What Degree? Which University?" had attracted more than 22,000 visitors and expanded to provide information about universities across Australia. Today, the website covers 23 Australian universities and is staffed by 17 undergraduate and postgraduate students Australia-wide, who manage and produce the content for the site. "What Degree? Which University?" claims to have had 77,500 visits to the website (55,000 of which being unique visitors) and