Discovery and development of statins Discovery and development of statins The discovery of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related diseases. Hypercholesterolemia is considered to be one of the major risk factors for atherosclerosis which often leads to cardiovascular, cerebrovascular and peripheral vascular diseases. The statins inhibit cholesterol synthesis in the body and that leads to reduction in blood cholesterol levels, which is thought to reduce the risk of atherosclerosis and diseases caused by it. More than 100 years ago a German pathologist named Rudolf Virchow discovered that cholesterol was to be found in the artery
Religion and drugs illegality of cannabis in many nations is evidence of persecution of Rastafari. They are not surprised that it is illegal, viewing Cannabis as a powerful substance that opens people's minds to the truth – something the Babylon system, they reason, clearly does not want. Cannabis use is contrasted with the use of alcohol and other drugs, which they feel destroy the mind. Alcoholic drinks are commonly used during Asatru blots but non-alcoholic drinks can be substituted. Religion and drugs Many religions have expressed positions on what is acceptable to consume as a means of intoxication for spiritual, pleasure, or medicinal