Cinchona ledgeriana" had a yield of 8 to 13 percent quinine in bark grown in Dutch Indonesia which effectively out-competed the British Indian production. It was only later that the English saw the value and sought to obtain the seeds of "C. ledgeriana" from the Dutch. During World War II, the Japanese conquered Java and the United States lost access to the cinchona plantations that supplied war-critical quinine medication. Botanical expeditions – called Cinchona Missions – were launched in 1942-1944 to explore promising areas of South America in an effort to locate cinchona species that contained quinine and could be harvested
History of pharmacy in the United States number of programs in the history of medicine, history of pharmacy programs remain few in number in the United States. As soon as Columbus started his explorations of the Americas in the late 15th century, a European effort to find valuable medicinal plants among the flora of the New World to add to the medical canon got underway. Early New World medicines uncovered included guaiacum from the West Indies (for coughs, rheumatism and a wide variety of other uses), sassafras from Florida, copaiba from Brazil, Peru balsam and, most famously, cinchona bark from Peru, also called "Jesuit's bark" in honor