Discovery and development of statins Discovery and development of statins The discovery of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related diseases. Hypercholesterolemia is considered to be one of the major risk factors for atherosclerosis which often leads to cardiovascular, cerebrovascular and peripheral vascular diseases. The statins inhibit cholesterol synthesis in the body and that leads to reduction in blood cholesterol levels, which is thought to reduce the risk of atherosclerosis and diseases caused by it. More than 100 years ago a German pathologist named Rudolf Virchow discovered that cholesterol was to be found in the artery
What Kind of an American are You? What Kind of an American are You? What Kind of an American are you?, also known as What Kind of American are you?, is a World War I era song released in 1917. Albert Von Tilzer composed the music. Lew Brown and Charles R. McCarron wrote the lyrics. The song was published by Broadway Music Co. of New York, New York. On the cover is a gray drawing of Uncle Sam pointing. A map of the United States is featured on the lower half of the cover. The song was written for voice and piano. The sheet music can be