Statin either the LDL receptor or apolipoprotein B genes, both of which are responsible for LDL clearance from the blood. Statins remain a first-line treatment in familial hypercholesterolemia, although other cholesterol-reducing measures may be required. In people with homozygous deficiencies, statins may still prove helpful, albeit at high doses and in combination with other cholesterol-reducing medications. A 2014 meta-analysis found that statins could reduce the risk of contrast-induced nephropathy by 53% in people undergoing coronary angiography/percutaneous interventions. The effect was found to be stronger among those with preexisting kidney dysfunction or diabetes mellitus. The most important adverse side effects are muscle
Religion and drugs illegality of cannabis in many nations is evidence of persecution of Rastafari. They are not surprised that it is illegal, viewing Cannabis as a powerful substance that opens people's minds to the truth – something the Babylon system, they reason, clearly does not want. Cannabis use is contrasted with the use of alcohol and other drugs, which they feel destroy the mind. Alcoholic drinks are commonly used during Asatru blots but non-alcoholic drinks can be substituted. Religion and drugs Many religions have expressed positions on what is acceptable to consume as a means of intoxication for spiritual, pleasure, or medicinal