Bee sting most aggressive stinging insects are vespid wasps (including bald-faced hornets and other yellowjackets) and hornets (especially the Asian giant hornet). All of these insects aggressively defend their nests. Although for most people a bee sting is painful but otherwise relatively harmless, in people with insect sting allergy, stings may trigger a dangerous anaphylactic reaction that is potentially deadly. Additionally, honey bee stings release pheromones that prompt other nearby bees to attack. A honey bee that is away from the hive foraging for nectar or pollen will rarely sting, except when stepped on or roughly handled. Honey bees will actively seek
Hornet visible under high magnification) and can easily be withdrawn and so are not pulled out of their bodies when disengaging. The toxicity of hornet stings varies according to hornet species; some deliver just a typical insect sting, while others are among the most venomous known insects. Single hornet stings are not in themselves fatal, except sometimes to allergic victims. Multiple stings by non-European hornets may be fatal because of highly toxic species-specific components of their venom. The stings of the Asian giant hornet ("Vespa mandarinia") are among the most venomous known, and are thought to cause 30–50 human deaths annually