U.S. Route 66 in Kansas U.S. Route 66 in Kansas U.S. Route 66 (US 66, Route 66), the historic east–west US highway between Chicago, Illinois and Santa Monica, California, passed through one brief segment in the southeastern corner of Kansas. It entered the state south of Baxter Springs and continued north until it crossed the Brush Creek, from where it turned east and left the state in Galena. After the decertification of the highway in 1985, this road segment was numbered as US-69 (alternate) from Quapaw, Oklahoma north to Riverton, Kansas and as K-66 (Kansas highway) from Riverton east to Route 66 in Missouri. The
U.S. Route 59 in Kansas US-59 reaches the south side of Lawrence and crosses K-10, known as the South Lawrence Trafficway, which heads west as a Super-2 toward Clinton Lake, the Kansas Turnpike, and Lecompton; and east as a divided freeway toward Olathe and Lenexa. Prior to November 2016, K-10 was merged with US-59 between the South Lawrence Trafficway and 23rd Street due to lawsuits over the completion of the road. In Lawrence, US-59 runs along Iowa Street, home to many retail shopping centers and fast-food restaurants. North of 23rd Street/Clinton Parkway, US-59 runs along the western edge of the University of Kansas. After crossing