Discovery and development of statins different pharmacophore structure were found. This structure-based virtual screening procedure is considered promising for rational quest and optimization of potential novel HGMR inhibitors. Discovery and development of statins The discovery of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related diseases. Hypercholesterolemia is considered to be one of the major risk factors for atherosclerosis which often leads to cardiovascular, cerebrovascular and peripheral vascular diseases. The statins inhibit cholesterol synthesis in the body and that leads to reduction in blood cholesterol levels, which is thought to reduce the risk of atherosclerosis and diseases caused
We Are Drugs Are Drugs", was released for streaming on September 8, 2016. The band played the 2016 iteration of Lollapalooza to promote the EP as well. We Are Drugs We Are Drugs is a studio EP by American alternative rock band Third Eye Blind. Preceded by the release of the single "Cop vs. Phone Girl" on July 25, 2016, "We Are Drugs" was published on October 7, 2016. As early as 2012, Third Eye Blind frontman Stephan Jenkins stated that following the release of their fifth album, they would cease releasing full albums, in favor of smaller EP releases. After the band