Quinine London. It remained the antimalarial drug of choice until the 1940s, when other drugs took over. The form of quinine most effective in treating malaria was found by Charles Marie de La Condamine in 1737. In 1820, French researchers Pierre Joseph Pelletier and Joseph Bienaimé Caventou first isolated quinine from the bark of a tree in the genus "Cinchona" - probably "Cinchona officinalis" - and subsequently named the substance. The name was derived from the original Quechua (Inca) word for the cinchona tree bark, "quina" or "quina-quina", which means "bark of bark" or "holy bark". Prior to 1820, the bark
The Giving Tree first edition of the book, consisting of only 5,000–7,500 copies, in 1964. The book follows the lives of a female apple tree and a boy, who develop a relationship with one another. The tree is very "giving" and the boy evolves into a "taking" teenager, man, then elderly man. Despite the fact that the boy ages in the story, the tree addresses the boy as "Boy" his entire life. In his childhood, the boy enjoys playing with the tree, climbing her trunk, swinging from her branches, carving "Me + T (Tree)" into the bark, and eating her apples. However, as