Quinine using the bark of the cinchona tree for that purpose. While its effect in treating malaria (and malaria-induced shivering) was unrelated to its effect in controlling shivering from rigors, it was a successful medicine against malaria. At the first opportunity, Salumbrino sent a small quantity to Rome for testing as a malaria treatment. In the years that followed, cinchona bark, known as Jesuit's bark or Peruvian bark, became one of the most valuable commodities shipped from Peru to Europe. When King Charles II was cured of malaria at the end of the 17th Century with quinine, it became popular in
Schedula Romana treatment for malaria was found in the forests of the Andes in Peru. A such called fever tree, whose bark, made into powder and given as a beverage, cured the fevers and was known to have produced miraculous results in the local population. The bark was obtained from several species of the genus "Cinchona", of the Rubiaceae family. Popularized in Europe through the work of jesuits in America, the cinchona tree bark came to be known as Jesuit's bark. Perhaps the most prominent popularizer of the Jesuit's bark was a Spanish Jesuit Cardinal, Juan de Lugo. In 1643, Cardinal Lugo