Clarithromycin CYP3A4, involved in the metabolism of many other commonly prescribed drugs. Taking clarithromycin with other medications that are metabolized by CYP3A4 may lead to unexpected increases or decreases in drug levels. A few of the common interactions are listed below. Clarithromycin has been observed to have a dangerous interaction with colchicine as the result of inhibition of CYP3A4 metabolism and P-glycoprotein transport. Combining these two drugs may lead to fatal colchicine toxicity, particularly in patients with renal insufficiency. Taking clarithromycin concurrently with certain statins (a class of drugs used to reduce blood serum cholesterol levels) increases the risk of side
Fire in the Blood (2013 film) Fire in the Blood (2013 film) Fire in the Blood is a 2013 documentary film by Dylan Mohan Gray depicting the intentional obstruction of access to low-cost antiretroviral drugs used in the treatment of HIV/AIDS to people in Africa and other parts the global south, driven by multinational pharmaceutical companies holding patent monopolies and various Western governments (above all those of the United States, European Union and Switzerland) consistently doing these companies' bidding. The film details how the battle against this genocidal blockade, estimated to have resulted in no less than ten- to twelve million completely unnecessary deaths, was fought