Clarithromycin CYP3A4, involved in the metabolism of many other commonly prescribed drugs. Taking clarithromycin with other medications that are metabolized by CYP3A4 may lead to unexpected increases or decreases in drug levels. A few of the common interactions are listed below. Clarithromycin has been observed to have a dangerous interaction with colchicine as the result of inhibition of CYP3A4 metabolism and P-glycoprotein transport. Combining these two drugs may lead to fatal colchicine toxicity, particularly in patients with renal insufficiency. Taking clarithromycin concurrently with certain statins (a class of drugs used to reduce blood serum cholesterol levels) increases the risk of side
Drugs in Cambodia had established a ring to transport synthetic drugs from Cambodia to Vietnam across the border for the drugs to be distributed in cafes, bars, and discos. According to initial investigators, the ring had been operating for nearly a decade The UNODC is mandated to assist Member States in their struggle against illicit drugs, crime and terrorism. The UNODC is also working with high ranking government officials to lower illicit drugs and corruption. The UNODC is constantly updated on the country’s drug control and crime prevention efforts. Drugs in Cambodia In Cambodia, drugs can be readily obtained and are easily accessible,