Discovery and development of statins trials showed very good inhibitory effect as in clinical trials, however in a long term toxicity study in dogs it resulted in toxic effects at higher doses and as a result was believed to be too toxic to be given to humans. In 1978, Alfred Alberts and colleagues at Merck Research Laboratories discovered a new natural product in a fermentation broth of "Aspergillus terreus", their product showed good HMGR inhibition and they named the product mevinolin, which later became known as lovastatin. The cholesterol controversy began in the early promotion of statins. Statins are a competitive antagonists of HMG CoA,
We Are All on Drugs We Are All on Drugs "We Are All on Drugs" is a song by American alternative rock band Weezer. It was released as the second single from the band's 2005 album, "Make Believe". "We Are All on Drugs" was released to radio on July 12, 2005. The song is not specifically about drugs. Rather, Rivers Cuomo has said that it is more generally about the over-stimulated society addicted to the internet, gambling, drugs and relationships. The song went into mixing with two lines in the bridge:, "I want to confiscate your drugs/ I don't think I can get enough", and