Cinchona Totaquina required a minimum of 70% crystallizable alkaloids of which at least 15% was to be quinine with not more than 20% amorphous alkaloids. There are at least 24 species recognized by botanists. There are likely several unnamed species and many intermediate forms that have arisen due to the plants' tendency to hybridize. Cinchona Cinchona is a genus of flowering plants in the family Rubiaceae containing at least 23 species of trees and shrubs. They are native to the tropical Andean forests of western South America. A few species are reportedly naturalized in Central America, Jamaica, French Polynesia, Sulawesi, Saint
Analgesic nephropathy between the 1960s and 1980s. As the use of phenacetin declined, so too did the prevalence of analgesic nephropathy as a cause of end-stage kidney disease. Data from Switzerland, for example, demonstrated a decline in the prevalence of analgesic nephropathy among people with end-stage kidney disease, from 28% in 1981 to 12% in 1990. An autopsy study performed in Switzerland suggested that the prevalence of analgesic nephropathy in the general population has likewise decreased; the prevalence was 3% in 1980 and 0.2% in 2000. While these data demonstrate that analgesic nephropathy has been all but eliminated in some regions, in