Cinchona genus is the source of a variety of alkaloids, the most familiar of which is quinine, an antipyretic (antifever) agent especially useful in treating malaria. Cinchona alkaloids include: They find use in organic chemistry as organocatalysts in asymmetric synthesis. Alongside the alkaloids, many cinchona barks contain cinchotannic acid, a particular tannin, which by oxidation rapidly yields a dark-coloured phlobaphene called red cinchonic, cinchono-fulvic acid or cinchona red. In 1934, efforts to make malaria drugs cheap and effective for use across countries led to the development of a standard called "totaquina" proposed by the Malaria Commission of the League of Nations.
Cinchona prefer the pronunciation for the common name of the plant. The national tree of Peru is in the genus "Cinchona". "Cinchona" plants belong to the family Rubiaceae and are large shrubs or small trees with evergreen foliage, growing in height. The leaves are opposite, rounded to lanceolate and 10–40 cm long. The flowers are white, pink or red, produced in terminal panicles. The fruit is a small capsule containing numerous seeds. A key character of the genus is that the flowers have marginally hairy corolla lobes. The tribe Cinchoneae includes other genera "Cinchonopsis", "Jossia", "Ladenbergia", "Remijia", "Stilpnophyllum", and "Ciliosemina". In