History of pharmacy in the United States of its discoverer, which became the first effective treatment for malaria. The active ingredient of this cinchona bark, quinine, was the primary treatment for malaria well into the 1940s. "About 170 drugs used by the Indians of British North America, and perhaps 50 used by the indigenous people of the Caribbean, Mexico, Central and South America" became important enough in the U.S. (as the practitioners of chemistry and pharmacy eventually catalogued, analyzed and understood them) to merit listing in the United States Pharmacopoeia (est. 1820) or the National Formulary. In the early 1700s, James Oglethorpe, founder of the Georgia colony,
Bark pocket indicator of air pollutants during which the time they formed. They can be used to monitor heavy metals such as lead and copper, as dust or other matter deposited on the bark at the time of formation is still present. One study analysed the amount of polycyclic aromatic hydrocarbons (PAHs) present in bark pockets as a historical record of air quality, possible due to the interaction between PAHs and lipids in the bark. Bark pocket Bark pockets can be formed by inosculation, formation of a tree fork, encapsulation of a branch, joining together of an uneven trunk, or encapsulation of