Statin either the LDL receptor or apolipoprotein B genes, both of which are responsible for LDL clearance from the blood. Statins remain a first-line treatment in familial hypercholesterolemia, although other cholesterol-reducing measures may be required. In people with homozygous deficiencies, statins may still prove helpful, albeit at high doses and in combination with other cholesterol-reducing medications. A 2014 meta-analysis found that statins could reduce the risk of contrast-induced nephropathy by 53% in people undergoing coronary angiography/percutaneous interventions. The effect was found to be stronger among those with preexisting kidney dysfunction or diabetes mellitus. The most important adverse side effects are muscle
Blood bike Blood bike A blood bike is a motorcycle used to courier urgent and emergency medical items including blood, X-rays, samples, drugs, and documentation between hospitals and other healthcare facilities. In the United Kingdom and Ireland a network of largely independent registered charities, whose members are all unpaid volunteers, provide blood bike courier services in collaboration with their local healthcare authorities. Many are represented through the Nationwide Association of Blood Bikes (NABB). Commercial blood bike courier services also exist. The first blood bike volunteer group to be established was the Emergency Volunteer Service (EVS), formed in 1962 in Surrey, England, by