Clarithromycin CYP3A4, involved in the metabolism of many other commonly prescribed drugs. Taking clarithromycin with other medications that are metabolized by CYP3A4 may lead to unexpected increases or decreases in drug levels. A few of the common interactions are listed below. Clarithromycin has been observed to have a dangerous interaction with colchicine as the result of inhibition of CYP3A4 metabolism and P-glycoprotein transport. Combining these two drugs may lead to fatal colchicine toxicity, particularly in patients with renal insufficiency. Taking clarithromycin concurrently with certain statins (a class of drugs used to reduce blood serum cholesterol levels) increases the risk of side
What Are The Theosophists? often attracted all sorts of neurotics, hysterics and even madmen: "All organisations which depend on enthusiasm and opposition to conventional opinion suffer from this problem to some degree; Theosophy appears to have been especially prone to it. The permanent residents at Adyar during the 1880s and '90s were typical. A quarrelsome collection of minor English aristocrats, rich American widows, German professors, Indian mystics and hangerson of every description, they were all eager to have their say, especially during Olcott's prolonged absences, and all ready to quarrel with one another." What Are The Theosophists? "What Are The Theosophists?" is an editorial