Statin either the LDL receptor or apolipoprotein B genes, both of which are responsible for LDL clearance from the blood. Statins remain a first-line treatment in familial hypercholesterolemia, although other cholesterol-reducing measures may be required. In people with homozygous deficiencies, statins may still prove helpful, albeit at high doses and in combination with other cholesterol-reducing medications. A 2014 meta-analysis found that statins could reduce the risk of contrast-induced nephropathy by 53% in people undergoing coronary angiography/percutaneous interventions. The effect was found to be stronger among those with preexisting kidney dysfunction or diabetes mellitus. The most important adverse side effects are muscle
Biodiversity and drugs example, caffeine, methyl salicylate and quinine. Streptomycin, neomycin, and erythromycin are derived from tropical soil fungi. A lot of plant species are used in today's studies and have been exhaustively studied for their potential value as source of drugs. It is possible that some plant species may be a source of drugs against high blood pressure, AIDS or heart troubles. In China, Japan, India and Germany, there is a great deal of interest in and support for the search for new drugs from higher plants. Each species carries unique genetic material in its DNA and in its chemical factory responding