History of pharmacy in the United States of its discoverer, which became the first effective treatment for malaria. The active ingredient of this cinchona bark, quinine, was the primary treatment for malaria well into the 1940s. "About 170 drugs used by the Indians of British North America, and perhaps 50 used by the indigenous people of the Caribbean, Mexico, Central and South America" became important enough in the U.S. (as the practitioners of chemistry and pharmacy eventually catalogued, analyzed and understood them) to merit listing in the United States Pharmacopoeia (est. 1820) or the National Formulary. In the early 1700s, James Oglethorpe, founder of the Georgia colony,
Alexander von Humboldt a center of learning in the U.S., Humboldt met with some of the major scientific figures of the era, including chemist and anatomist Caspar Wistar, who pushed for compulsory smallpox vaccination, and botanist Benjamin Smith Barton, as well as physician Benjamin Rush, a signer of the Declaration of Independence, who wished to hear about cinchona bark from a South American tree, which cured fevers. Humboldt later published a treatise in English on cinchona. After arriving in Washington D.C, Humboldt held numerous intense discussions with Jefferson on both scientific matters and also his year-long stay in New Spain. Jefferson had only