Quinine using the bark of the cinchona tree for that purpose. While its effect in treating malaria (and malaria-induced shivering) was unrelated to its effect in controlling shivering from rigors, it was a successful medicine against malaria. At the first opportunity, Salumbrino sent a small quantity to Rome for testing as a malaria treatment. In the years that followed, cinchona bark, known as Jesuit's bark or Peruvian bark, became one of the most valuable commodities shipped from Peru to Europe. When King Charles II was cured of malaria at the end of the 17th Century with quinine, it became popular in
Quercus leucotrichophora to October. Naturally, it regenerates via seeds. "Quercus leucotrichophora" is distributed in Northern India, Nepal, Myanmar, Pakistan, and Sri Lanka. In Nepal, it naturally occurs at 1500–2700 m in forested areas in association with "Rhododendron arboreum". In the Himalayas, "Quercus leucotrichophora" is lopped for fodder from December to June. Its wood is used in building purposes and as a good fuel. The acorns are edible, and the seeds can be roasted to make a coffee substitute. "Quercus leucotrichophora" also has uses in ethnomedicine, the gum being used for treating colds and as an analgesic. The tree is affected with many