History of pharmacy in the United States of its discoverer, which became the first effective treatment for malaria. The active ingredient of this cinchona bark, quinine, was the primary treatment for malaria well into the 1940s. "About 170 drugs used by the Indians of British North America, and perhaps 50 used by the indigenous people of the Caribbean, Mexico, Central and South America" became important enough in the U.S. (as the practitioners of chemistry and pharmacy eventually catalogued, analyzed and understood them) to merit listing in the United States Pharmacopoeia (est. 1820) or the National Formulary. In the early 1700s, James Oglethorpe, founder of the Georgia colony,
Tree converted into bark and the cambium layer creates new phloem and xylem cells. The bark is inelastic. Eventually the growth of a tree slows down and stops and it gets no taller. If damage occurs the tree may in time become hollow. Leaves are structures specialised for photosynthesis and are arranged on the tree in such a way as to maximise their exposure to light without shading each other. They are an important investment by the tree and may be thorny or contain phytoliths, lignins, tannins or poisons to discourage herbivory. Trees have evolved leaves in a wide range of