Clarithromycin CYP3A4, involved in the metabolism of many other commonly prescribed drugs. Taking clarithromycin with other medications that are metabolized by CYP3A4 may lead to unexpected increases or decreases in drug levels. A few of the common interactions are listed below. Clarithromycin has been observed to have a dangerous interaction with colchicine as the result of inhibition of CYP3A4 metabolism and P-glycoprotein transport. Combining these two drugs may lead to fatal colchicine toxicity, particularly in patients with renal insufficiency. Taking clarithromycin concurrently with certain statins (a class of drugs used to reduce blood serum cholesterol levels) increases the risk of side
Masquerade in Blood the second and last for drummer Atomic Steif, since the former was arrested in 1996 for possession of drugs, while the latter left the band for personal reasons. "Masquerade in Blood" continues in the same crossover thrash vein as their previous studio effort "Get What You Deserve" (which was released in the previous year), however it is most notable for introducing a new groove metal style, with "overwhelming" death metal being present on select songs. AllMusic's Eduardo Rivadavia gave the album two stars out of five, noting it as being "something of a return to form" for the band. However,