Malaria saved the lives of thousands of workers and helped develop the methods used in future public-health campaigns against the disease. The first effective treatment for malaria came from the bark of cinchona tree, which contains quinine. This tree grows on the slopes of the Andes, mainly in Peru. The indigenous peoples of Peru made a tincture of cinchona to control fever. Its effectiveness against malaria was found and the Jesuits introduced the treatment to Europe around 1640; by 1677, it was included in the London Pharmacopoeia as an antimalarial treatment. It was not until 1820 that the active ingredient, quinine,
Cinchona prefer the pronunciation for the common name of the plant. The national tree of Peru is in the genus "Cinchona". "Cinchona" plants belong to the family Rubiaceae and are large shrubs or small trees with evergreen foliage, growing in height. The leaves are opposite, rounded to lanceolate and 10–40 cm long. The flowers are white, pink or red, produced in terminal panicles. The fruit is a small capsule containing numerous seeds. A key character of the genus is that the flowers have marginally hairy corolla lobes. The tribe Cinchoneae includes other genera "Cinchonopsis", "Jossia", "Ladenbergia", "Remijia", "Stilpnophyllum", and "Ciliosemina". In