Quinine using the bark of the cinchona tree for that purpose. While its effect in treating malaria (and malaria-induced shivering) was unrelated to its effect in controlling shivering from rigors, it was a successful medicine against malaria. At the first opportunity, Salumbrino sent a small quantity to Rome for testing as a malaria treatment. In the years that followed, cinchona bark, known as Jesuit's bark or Peruvian bark, became one of the most valuable commodities shipped from Peru to Europe. When King Charles II was cured of malaria at the end of the 17th Century with quinine, it became popular in
Christmas tree production in the United States million Christmas trees valued at approximately $120 million. The majority of Christmas tree production occurs in the Willamette Valley region including Benton, Clackamas, Marion, Polk and Yamhill counties. In 2015, Washington State had approximately 250 Christmas tree farms with a combined 23,000 acres, yielding 2.3 million Christmas trees valued at approximately $35 million. The majority of Christmas tree production occurs in the western and southern portions of the Puget Sound region including Kitsap, Lewis, Mason and Thurston counties. Aside from Pennsylvania, several U.S. states in the Great Lakes region are key Christmas tree producers. The two most important production areas