Quinine the Quechua, who are indigenous to Peru, Bolivia and Ecuador, to halt shivering due to low temperatures. The Quechuas would mix the ground bark of cinchona trees with sweetened water to offset the bark's bitter taste, thus producing tonic water. The Jesuits were the first to bring cinchona to Europe. The Spanish were aware of the medicinal properties of cinchona bark by the 1570s or earlier: Nicolás Monardes (1571) and Juan Fragoso (1572) both described a tree that was subsequently identified as the cinchona tree and whose bark was used to produce a drink to treat diarrhea. Quinine has been
Cinchona knighted. For the role in establishing cinchona in Indonesia, Hasskarl was knighted with the Dutch order of the Lion. "Cinchona" species are used as food plants by the larvae of some Lepidoptera species, including the engrailed, the commander, and members of the genus "Endoclita", including "E. damor", "E. purpurescens" and "E. sericeus". "Cinchona pubescens" has grown uncontrolled on some islands such as the Galapagos where it has posed the risk of outcompeting native plant species. In herbalism, cinchona bark was used as an adulterant in Jesuit's bark or Peruvian bark which originally is thought to have referred to "Myroxylon peruiferum",