U.S. Route 66 in Kansas U.S. Route 66 in Kansas U.S. Route 66 (US 66, Route 66), the historic east–west US highway between Chicago, Illinois and Santa Monica, California, passed through one brief segment in the southeastern corner of Kansas. It entered the state south of Baxter Springs and continued north until it crossed the Brush Creek, from where it turned east and left the state in Galena. After the decertification of the highway in 1985, this road segment was numbered as US-69 (alternate) from Quapaw, Oklahoma north to Riverton, Kansas and as K-66 (Kansas highway) from Riverton east to Route 66 in Missouri. The
U.S. Route 75 in Kansas 4 miles north of the state line. South of Neodesha, US 75 overlaps with US 400 as a 2 lane freeway. At Interstate 35 (I-35), US 75 becomes a two-lane expressway again, passing east of Melvern Lake. About 15 miles south of Topeka, the highway becomes a four lane freeway. US 75 crosses the Kansas Turnpike without any direct access and drivers must use I-470 to access the turnpike. US 75 runs around the main part of the city along I-470 and I-70. Leaving Topeka, US 75 becomes its own route again. Between Hoyt and Holton, the highway runs along