Cinchona economically practical source of quinine, a drug that is still recommended for the treatment of "falciparum" malaria. The Italian botanist Pietro Castelli wrote a pamphlet noteworthy as being the first Italian publication to mention the cinchona. By the 1630s (or 1640s, depending on the reference), the bark was being exported to Europe. In the late 1640s, the method of use of the bark was noted in the "Schedula Romana." English King Charles II called upon Robert Talbor, who had become famous for his miraculous malaria cure. Because at that time the bark was in religious controversy, Talbor gave the king
Bark (botany) the ground to where the main branching starts) of the tree. Bark tissues make up by weight between 10–20% of woody vascular plants and consists of various biopolymers, tannins, lignin, suberin, suberan and polysaccharides. Up to 40% of the bark tissue is made of lignin which forms an important part of a plant providing structural support by crosslinking between different polysaccharides, such as cellulose. Condensed tannin, which are in fairly high concentration in bark tissue, is thought to inhibit decomposition. It could be due to this factor that the degradation of lignin is far less pronounced in bark tissue than