Cinchona economically practical source of quinine, a drug that is still recommended for the treatment of "falciparum" malaria. The Italian botanist Pietro Castelli wrote a pamphlet noteworthy as being the first Italian publication to mention the cinchona. By the 1630s (or 1640s, depending on the reference), the bark was being exported to Europe. In the late 1640s, the method of use of the bark was noted in the "Schedula Romana." English King Charles II called upon Robert Talbor, who had become famous for his miraculous malaria cure. Because at that time the bark was in religious controversy, Talbor gave the king
Cinchona people. Italian sources spelt Quina as Cina which was a source of confusion with "Smilax" from China. Haggis argued that Qina and Jesuit's bark actually referred to "Myroxylon peruiferum" or Peruvian balsam and that this was an item of importance in Spanish trade in the 1500s. Over time, the bark of the "Myroxylon" was adulterated with the similar looking bark of what we now know as "Cinchona". Gradually the adulterant became the main product that was the key therapeutic ingredient used in malarial therapy. The bark was included as "Cortex Peruanus" in the London Pharmacopoeia in 1677. The "fever tree"