Cinchona pubescens Cinchona pubescens Cinchona pubescens, also known as red cinchona and quina (Quechua) ( "Cascarilla, cinchona"; "quina-do-amazonas, quineira"), is native to Central and South America. It is known as a medicinal plant for its bark's high quinine content- and has similar uses to "Cinchona officinalis" in the production of quinine, most famously used for treatment of malaria. "C. pubescens" varies from small to large in size, growing to 10 meters in height (33 ft). When cut, the bark tends to turn red. Leaves are elliptical to oblate and thin. The leaves have pubescent teeth that turn red when they are older,
History of malaria and make them more susceptible to other diseases. Spanish missionaries found that fever was treated by Amerindians near Loxa (Peru) with powder from Peruvian bark (later established to be from any of several trees of genus "Cinchona"). It was used by the Quechua Indians of Peru to reduce the shaking effects caused by severe chills. Jesuit Brother Agostino Salumbrino (1561–1642), who lived in Lima and was an apothecary by training, observed the Quechua using the bark of the cinchona tree for that purpose. While its effect in treating malaria (and hence malaria-induced shivering) was unrelated to its effect in controlling