Pleiotropy (drugs) can respond to them, because the endogenous ones are endocrine messengers. Pleiotropy (drugs) In pharmacology, pleiotropy includes all of a drug's actions other than those for which the agent was specifically developed. It may include adverse effects which are detrimental ones, but is often used to denote additional beneficial effects. For example, statins are HMG-CoA reductase inhibitors that primarily act by decreasing cholesterol synthesis, but which are believed to have other beneficial effects, including acting as antioxidants and stabilizing atherosclerotic plaques. Steroid drugs, such as prednisone and prednisolone, have pleiotropic effects, including systemic ones, for the same reason that endogenous
The Young Blood Chronicles a parking lot, Joe at a gas station and Pete on a rooftop. The Vixens bring Pete, Andy and Joe to a dinner table, at which Patrick is already seated. They are strapped to chairs and hooked to intravenous drips. They are served blood wine, hookahs and snuffable colored powder resembling cocaine. The women then serve them cobbler, fruit and Patrick's organs. The drugs make them believe they are dancing with their captors and naked women wearing bloody animal masks, yet are left still bound to their chairs. The briefcase is delivered to a vehicle with the license plate "RATATAT".