Quinine using the bark of the cinchona tree for that purpose. While its effect in treating malaria (and malaria-induced shivering) was unrelated to its effect in controlling shivering from rigors, it was a successful medicine against malaria. At the first opportunity, Salumbrino sent a small quantity to Rome for testing as a malaria treatment. In the years that followed, cinchona bark, known as Jesuit's bark or Peruvian bark, became one of the most valuable commodities shipped from Peru to Europe. When King Charles II was cured of malaria at the end of the 17th Century with quinine, it became popular in
Jesuit's bark "Pulvis Patrum". The history of cinchona bark, which dates back more than 300 years, has greatly influenced that of pharmacy, botany, medicine, trade, theoretical and practical chemistry, and tropical agriculture. Circa 1650, the physician Sebastiano Bado declared that this bark had proved more precious to mankind than all the gold and silver that the Spaniards had obtained from South America, and the world confirmed his opinion. See also Swords, Ships and Sugar - The History of Nevis, by Vincent K. Hubbard, p. 73, where a large amount of "Peruvian Bark" had been captured by the pirate Basil Ringrose, also known