Malaria saved the lives of thousands of workers and helped develop the methods used in future public-health campaigns against the disease. The first effective treatment for malaria came from the bark of cinchona tree, which contains quinine. This tree grows on the slopes of the Andes, mainly in Peru. The indigenous peoples of Peru made a tincture of cinchona to control fever. Its effectiveness against malaria was found and the Jesuits introduced the treatment to Europe around 1640; by 1677, it was included in the London Pharmacopoeia as an antimalarial treatment. It was not until 1820 that the active ingredient, quinine,
Bark (botany) ridges. In the cork oak ("Quercus suber") the bark is thick enough to be harvested as a cork product without killing the tree; in this species the bark may get very thick (e.g. more than 20 cm has been reported). Some barks can be removed in long sheets; the smooth surfaced bark of birch trees has been used as a covering in the making of canoes, as the drainage layer in roofs, for shoes, backpacks etc. The most famous example of using birch bark for canoes is the birch canoes of North America. The inner bark (phloem) of some trees