Cinchona lost their plants when a wave took them off their ship. The Dutch sent Justus Hasskarl who brought plants that were then cultivated in Java from 1854. The English explorer Clements Markham went to collect plants that were introduced in Sri Lanka and the Nilgiris of southern India in 1860. The main species introduced were "Cinchona succirubra" or red bark, as its sap turned red on contact with air, and "Cinchona calisaya". The alkaloids quinine and cinchonine were extracted by Pelletier and Caventou in 1820. Later two more key alkaloids, quinidine and cinchonidine were identified and it became a routine
Christmas tree production in the United States million Christmas trees valued at approximately $120 million. The majority of Christmas tree production occurs in the Willamette Valley region including Benton, Clackamas, Marion, Polk and Yamhill counties. In 2015, Washington State had approximately 250 Christmas tree farms with a combined 23,000 acres, yielding 2.3 million Christmas trees valued at approximately $35 million. The majority of Christmas tree production occurs in the western and southern portions of the Puget Sound region including Kitsap, Lewis, Mason and Thurston counties. Aside from Pennsylvania, several U.S. states in the Great Lakes region are key Christmas tree producers. The two most important production areas