Cinchona in quinology to examine the contents of these components in assays. The yields of quinine in the cultivated trees were low and it took a while to develop sustainable methods to extract bark. In the meantime Charles Ledger and his native assistant Manuel collected another species from Bolivia. Manuel was caught and beaten by Bolivian officials leading to his death but Ledger obtained seeds of high quality which were offered to the British who were uninterested, leading to the rest being sold to the Dutch. The Dutch saw its value and multiplied the stock. The species later named as "Cinchona
Cinchona was finally described carefully by the astronomer Charles Marie de la Condamine who visited Quito in 1735 on a quest to measure an arc of the meridian. The species he described, "Cinchona officinalis," was however found to be of little therapeutic value. The first living plants seen in Europe were "C. calisaya" plants grown at the "Jardin des Plantes" from seeds collected by Hugh Algernon Weddell from Bolivia in 1846. José Celestino Mutis, physician to the Viceroy of Nueva Granada, Pedro Messia de la Cerda gathered information on cinchona in Colombia from 1760 and wrote a manuscript "El Arcano de