Cinchona economically practical source of quinine, a drug that is still recommended for the treatment of "falciparum" malaria. The Italian botanist Pietro Castelli wrote a pamphlet noteworthy as being the first Italian publication to mention the cinchona. By the 1630s (or 1640s, depending on the reference), the bark was being exported to Europe. In the late 1640s, the method of use of the bark was noted in the "Schedula Romana." English King Charles II called upon Robert Talbor, who had become famous for his miraculous malaria cure. Because at that time the bark was in religious controversy, Talbor gave the king
Bark pocket indicator of air pollutants during which the time they formed. They can be used to monitor heavy metals such as lead and copper, as dust or other matter deposited on the bark at the time of formation is still present. One study analysed the amount of polycyclic aromatic hydrocarbons (PAHs) present in bark pockets as a historical record of air quality, possible due to the interaction between PAHs and lipids in the bark. Bark pocket Bark pockets can be formed by inosculation, formation of a tree fork, encapsulation of a branch, joining together of an uneven trunk, or encapsulation of