Quinine London. It remained the antimalarial drug of choice until the 1940s, when other drugs took over. The form of quinine most effective in treating malaria was found by Charles Marie de La Condamine in 1737. In 1820, French researchers Pierre Joseph Pelletier and Joseph Bienaimé Caventou first isolated quinine from the bark of a tree in the genus "Cinchona" - probably "Cinchona officinalis" - and subsequently named the substance. The name was derived from the original Quechua (Inca) word for the cinchona tree bark, "quina" or "quina-quina", which means "bark of bark" or "holy bark". Prior to 1820, the bark
Christmas tree production in the United States million Christmas trees valued at approximately $120 million. The majority of Christmas tree production occurs in the Willamette Valley region including Benton, Clackamas, Marion, Polk and Yamhill counties. In 2015, Washington State had approximately 250 Christmas tree farms with a combined 23,000 acres, yielding 2.3 million Christmas trees valued at approximately $35 million. The majority of Christmas tree production occurs in the western and southern portions of the Puget Sound region including Kitsap, Lewis, Mason and Thurston counties. Aside from Pennsylvania, several U.S. states in the Great Lakes region are key Christmas tree producers. The two most important production areas