Quinine side effects include deafness, low blood platelets, and an irregular heartbeat. Use can make one more prone to sunburn. While it is unclear if use during pregnancy causes harm to the baby, use to treat malaria during pregnancy is still recommended. Quinine is an alkaloid, a naturally occurring chemical compound. How it works as a medicine is not entirely clear. Quinine was first isolated in 1820 from the bark of a cinchona tree. Bark extracts have been used to treat malaria since at least 1632. It is on the World Health Organization's List of Essential Medicines, the most effective and
Bark pocket Bark pocket Bark pockets can be formed by inosculation, formation of a tree fork, encapsulation of a branch, joining together of an uneven trunk, or encapsulation of another object. During inosculation, the bark trapped between the two joining trunk becomes surrounded with wood once the trunks fuse. The resulting bark pocket formed during inosculation or in a tree fork is referred to as included bark. When a branch is encapsulated, the outer bark on the branch may remain inside the wood of the tree, as the trunk widens and grows around the branch. Bark pockets can be used as an