Familial hypercholesterolemia disorder in two generations simultaneously." "The use of total cholesterol alone may best discriminate between people with and without FH between the ages of 1 to 9 years." Screening of toddlers has been suggested, and results of a trial on 10,000 one-year-olds were published in 2016. Work was needed to find whether screening was cost-effective, and acceptable to families. FH is usually treated with statins. Statins act by inhibiting the enzyme hydroxymethylglutaryl CoA reductase (HMG-CoA-reductase) in the liver. In response, the liver produces more LDL receptors, which remove circulating LDL from the blood. Statins effectively lower cholesterol and LDL levels,
What Are The Theosophists? often attracted all sorts of neurotics, hysterics and even madmen: "All organisations which depend on enthusiasm and opposition to conventional opinion suffer from this problem to some degree; Theosophy appears to have been especially prone to it. The permanent residents at Adyar during the 1880s and '90s were typical. A quarrelsome collection of minor English aristocrats, rich American widows, German professors, Indian mystics and hangerson of every description, they were all eager to have their say, especially during Olcott's prolonged absences, and all ready to quarrel with one another." What Are The Theosophists? "What Are The Theosophists?" is an editorial