Discovery and development of statins Discovery and development of statins The discovery of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related diseases. Hypercholesterolemia is considered to be one of the major risk factors for atherosclerosis which often leads to cardiovascular, cerebrovascular and peripheral vascular diseases. The statins inhibit cholesterol synthesis in the body and that leads to reduction in blood cholesterol levels, which is thought to reduce the risk of atherosclerosis and diseases caused by it. More than 100 years ago a German pathologist named Rudolf Virchow discovered that cholesterol was to be found in the artery
Drugs in Cambodia produced and traffickers export these drugs out of the country and or shipped throughout neighboring nations. The Ruak and Mekong rivers of these areas also influences the ease of how drugs are transported through this area. The drugs are transported through the Triangle by horse and donkey caravans to refineries where the drugs are further processed and refined to become more pure. They are then most frequently brought to the United States and other countries by couriers traveling on commercial airlines or they are smuggled into the country by shipping containers. Teng Bunma is one of the wealthiest people in