Discovery and development of statins trials showed very good inhibitory effect as in clinical trials, however in a long term toxicity study in dogs it resulted in toxic effects at higher doses and as a result was believed to be too toxic to be given to humans. In 1978, Alfred Alberts and colleagues at Merck Research Laboratories discovered a new natural product in a fermentation broth of "Aspergillus terreus", their product showed good HMGR inhibition and they named the product mevinolin, which later became known as lovastatin. The cholesterol controversy began in the early promotion of statins. Statins are a competitive antagonists of HMG CoA,
We Are Drugs The band focused on continuous sessions that would take a song from conception to completion. No guidelines or definitions of what the music should be or sound like were permitted during the sessions; this allowed the band to create the music they felt in the time they were working on it. Lyrics and vocals for the track "Weightless," however, were completed outside of the initial sessions: Jenkins didn't complete either until September 13, 2016—only three weeks before the EP was released. Jenkins states that the EP's name is meant to tie into their preceding album "Dopamine", with drugs being something