Cinchona pubescens Cinchona pubescens Cinchona pubescens, also known as red cinchona and quina (Quechua) ( "Cascarilla, cinchona"; "quina-do-amazonas, quineira"), is native to Central and South America. It is known as a medicinal plant for its bark's high quinine content- and has similar uses to "Cinchona officinalis" in the production of quinine, most famously used for treatment of malaria. "C. pubescens" varies from small to large in size, growing to 10 meters in height (33 ft). When cut, the bark tends to turn red. Leaves are elliptical to oblate and thin. The leaves have pubescent teeth that turn red when they are older,
Therapeutice Specialis ad Febres Periodicas Perniciosas who first systematically studied the effect of cinchona in the treatment of malaria, wrote a book which he titled "Therapeutice Specialis ad Febres Periodicas Perniciosas". One highlight of the "Therapeutice Specialis" is the drawing "tree of fevers", where different fevers, such as branches of the tree, are divided into categories: on the left, those that respond to cinchona, are shown as branches covered with bark, while on the right are those for which cinchona is ineffective, and are depicted as denuded leafless branches. Torti clearly identified cinchona as a specific therapy for intermittent fevers, as opposed to continued fevers, which