Malaria saved the lives of thousands of workers and helped develop the methods used in future public-health campaigns against the disease. The first effective treatment for malaria came from the bark of cinchona tree, which contains quinine. This tree grows on the slopes of the Andes, mainly in Peru. The indigenous peoples of Peru made a tincture of cinchona to control fever. Its effectiveness against malaria was found and the Jesuits introduced the treatment to Europe around 1640; by 1677, it was included in the London Pharmacopoeia as an antimalarial treatment. It was not until 1820 that the active ingredient, quinine,
Cinchona officinalis Cinchona officinalis Cinchona officinalis is a South American tree in the Rubiaceae family. It is native to wet montane forests in Colombia, Ecuador, Peru and Bolivia, between 1600–2700 meters above sea level. Cinchona officinalis is a shrub or tree with rugose bark and branchlets covered in minute hairs. Stipules lanceolate or oblong, acute or obtuse, glabrous. Leaves lanceolate to elliptic or ovate, usually about 10 cm. long and 3.5–4 cm. wide; acute, acuminate, or obtuse tip; base rounded to attenuate; coriaceous, glabrous above and often lustrous; glabrous beneath or puberulent or short-pilose, especially on the veins. Inflorescences in terminal panicles,