Pleiotropy (drugs) Pleiotropy (drugs) In pharmacology, pleiotropy includes all of a drug's actions other than those for which the agent was specifically developed. It may include adverse effects which are detrimental ones, but is often used to denote additional beneficial effects. For example, statins are HMG-CoA reductase inhibitors that primarily act by decreasing cholesterol synthesis, but which are believed to have other beneficial effects, including acting as antioxidants and stabilizing atherosclerotic plaques. Steroid drugs, such as prednisone and prednisolone, have pleiotropic effects, including systemic ones, for the same reason that endogenous steroid hormones do too: cells throughout the body have receptors that
What Degree? Which University? student life, student housing, and graduate opportunities for university leavers through the "Lifestyle", "Student Housing", "Survival Guide" and "After Uni" sections. The creator of "What Degree? Which University?" is David Handley, who is also the founding director of international sculpture exhibition, "Sculpture by the Sea". Handley first conceptualised "What Degree? Which University?" whilst studying his final year of Law at the University of Sydney. In 1988, "What Degree? Which University?" initially took form through university seminars held at the University of Sydney, allowing prospective students to compare degree options by hearing current and former students of undergraduate degree programs discuss