Cinchona in quinology to examine the contents of these components in assays. The yields of quinine in the cultivated trees were low and it took a while to develop sustainable methods to extract bark. In the meantime Charles Ledger and his native assistant Manuel collected another species from Bolivia. Manuel was caught and beaten by Bolivian officials leading to his death but Ledger obtained seeds of high quality which were offered to the British who were uninterested, leading to the rest being sold to the Dutch. The Dutch saw its value and multiplied the stock. The species later named as "Cinchona
Cinchona officinalis of malaria. Other alkaloids that are extracted from this tree include cinchonine, cinchonidine and quinidine. Cinchona officinalis Cinchona officinalis is a South American tree in the Rubiaceae family. It is native to wet montane forests in Colombia, Ecuador, Peru and Bolivia, between 1600–2700 meters above sea level. Cinchona officinalis is a shrub or tree with rugose bark and branchlets covered in minute hairs. Stipules lanceolate or oblong, acute or obtuse, glabrous. Leaves lanceolate to elliptic or ovate, usually about 10 cm. long and 3.5–4 cm. wide; acute, acuminate, or obtuse tip; base rounded to attenuate; coriaceous, glabrous above and often