Clarithromycin CYP3A4, involved in the metabolism of many other commonly prescribed drugs. Taking clarithromycin with other medications that are metabolized by CYP3A4 may lead to unexpected increases or decreases in drug levels. A few of the common interactions are listed below. Clarithromycin has been observed to have a dangerous interaction with colchicine as the result of inhibition of CYP3A4 metabolism and P-glycoprotein transport. Combining these two drugs may lead to fatal colchicine toxicity, particularly in patients with renal insufficiency. Taking clarithromycin concurrently with certain statins (a class of drugs used to reduce blood serum cholesterol levels) increases the risk of side
Drugs in Cambodia produced and traffickers export these drugs out of the country and or shipped throughout neighboring nations. The Ruak and Mekong rivers of these areas also influences the ease of how drugs are transported through this area. The drugs are transported through the Triangle by horse and donkey caravans to refineries where the drugs are further processed and refined to become more pure. They are then most frequently brought to the United States and other countries by couriers traveling on commercial airlines or they are smuggled into the country by shipping containers. Teng Bunma is one of the wealthiest people in