Statin either the LDL receptor or apolipoprotein B genes, both of which are responsible for LDL clearance from the blood. Statins remain a first-line treatment in familial hypercholesterolemia, although other cholesterol-reducing measures may be required. In people with homozygous deficiencies, statins may still prove helpful, albeit at high doses and in combination with other cholesterol-reducing medications. A 2014 meta-analysis found that statins could reduce the risk of contrast-induced nephropathy by 53% in people undergoing coronary angiography/percutaneous interventions. The effect was found to be stronger among those with preexisting kidney dysfunction or diabetes mellitus. The most important adverse side effects are muscle
What Are The Theosophists? What Are The Theosophists? "What Are The Theosophists?" is an editorial published in October 1879 in the theosophical magazine "The Theosophist." It was compiled by Helena Blavatsky and it was included the 2nd volume of the "Blavatsky Collected Writings." Arnold Kalnitsky wrote in his thesis that in this article "we find a rather expansive statement of... [Blavatsky's] thoughts at that moment about the status of the movement, the Theosophical Society, its objectives, and the issues it was confronting." He wrote that the article begins with a question whether the Theosophists "are they what they claim to be": researchers of the