Cinchona genus is the source of a variety of alkaloids, the most familiar of which is quinine, an antipyretic (antifever) agent especially useful in treating malaria. Cinchona alkaloids include: They find use in organic chemistry as organocatalysts in asymmetric synthesis. Alongside the alkaloids, many cinchona barks contain cinchotannic acid, a particular tannin, which by oxidation rapidly yields a dark-coloured phlobaphene called red cinchonic, cinchono-fulvic acid or cinchona red. In 1934, efforts to make malaria drugs cheap and effective for use across countries led to the development of a standard called "totaquina" proposed by the Malaria Commission of the League of Nations.
Bark hack Bark hack A bark hack is a tool used to remove pine tree bark to promote the flow of pine resin, which is used in naval stores production. The tool consists of a wooden shaft with a weighted butt and hook-like, replaceable, U-shaped blades at the head. The bark hack is swung much like an axe and is used to create a hatched chevron pattern ("cat face" or less frequently, a "blaze") into trees' exposed sapwood. The weighted end helps the operator follow through with the force necessary for the hooked blade to scoop out chips of hard pine wood.