Cinchona genus is the source of a variety of alkaloids, the most familiar of which is quinine, an antipyretic (antifever) agent especially useful in treating malaria. Cinchona alkaloids include: They find use in organic chemistry as organocatalysts in asymmetric synthesis. Alongside the alkaloids, many cinchona barks contain cinchotannic acid, a particular tannin, which by oxidation rapidly yields a dark-coloured phlobaphene called red cinchonic, cinchono-fulvic acid or cinchona red. In 1934, efforts to make malaria drugs cheap and effective for use across countries led to the development of a standard called "totaquina" proposed by the Malaria Commission of the League of Nations.
Bark! The Musical Bark! The Musical BARK! The Musical is a musical with music by David Troy Francis and lyrics by Gavin Geoffrey Dillard and Robert Schrock (with additional lyrics by Mark Winkler). The book is by Mark Winkler and Gavin Geoffrey Dillard. "BARK!" explores one day in the lives of six dogs in Deena's Doggie Daycare. These dogs include a little puppy who yearns to bark like a real dog, an opera singing poodle, and a street mutt who raps and sometimes cross dresses as a chihuahua. The entire show is presented from a dog’s point of view. "BARK!" made its world