Anna Morandi Manzolini in 1755 in the scientific knowledge of human anatomy as well as the accurate demonstration of anatomy in wax sculpture. During her famed household lectures on anatomy given before medical practitioners and grand tourists alike, she imparted expert knowledge of empirical anatomy derived from the dissection of, by her own account, of more than 1,000 cadavers, as well as of anatomical discoveries the couple and she alone made. She clearly demonstrated, both theoretically and practically, the wonderful structure of the human body. She also crafted two portrait busts in wax, both of which are currently on display at the Palazzo
18th century and the classical period (including Joseph Haydn and Wolfgang Amadeus Mozart). The 18th century also marked the end of the Polish–Lithuanian Commonwealth as an independent state. The once-powerful and vast kingdom, which had once conquered Moscow and defeated great Ottoman armies, collapsed under numerous invasions. Its semi-democratic government system was not robust enough to rival the neighboring monarchies of the Kingdom of Prussia, the Russian Empire and the Austrian Empire which divided the Commonwealth territories between themselves, changing the landscape of Central European politics for the next hundred years. European colonization of the Americas and other parts of the world