Psychedelic experience sources of some psychedelic drugs such as ayahuasca and mescaline-containing cacti are sometimes referred to as "plant teachers". Similarly, in a follow-up to the psilocybin and mysticism study at Johns Hopkins, researchers observed that psilocybin: "occasions personally and spiritually significant mystical experiences that predict long-term changes in behaviors, attitudes and values". Psychedelic experience includes the full range of mystical or religious experiential phenomena. Two scientific studies have concluded that psilocybin (a typical psychedelic compound that occurs naturally in psilocybin mushrooms) reliably triggers mystical-type experiences. The more recent study at Johns Hopkins University identified mystical experiences by means of several questionnaires
Mescaline experiences but they manifest more clearly with eyes closed and under low lighting conditions. Mescaline may cause Hallucinogen persisting perception disorder. As with LSD, synesthesia can occur especially with the help of music. An unusual but unique characteristic of mescaline use is the "geometricization" of three-dimensional objects. The object can appear flattened and distorted, similar to the presentation of a Cubist painting. Mescaline elicits a pattern of sympathetic arousal, with the peripheral nervous system being a major target for this substance. Mescaline is produced when products of natural mammalian catecholamine-based neuronal signalling such as dopamine and noradrenaline are subjected to