Susan C. Baker throughout the body. This disease also affects skin, mucous membranes, and the body's lymph nodes. Baker's lab is investigating the possibility of a viral causative agent for the disease. This disease mostly affects children under the age of 5. Causes remain unknown, however it is treatable within days if the symptoms are recognized early enough. If left untreated, it can lead to serious problems for the heart. Baker has also worked closely with coronaviruses, the causative agent of Severe Acute Respiratory Syndrome. These are viruses that affect mostly the upper respiratory and GI tract of humans and are named because
Chronic granulomatous disease from the name of the disease as children survived into adulthood. Gene therapy is currently being studied as a possible treatment for chronic granulomatous disease. CGD is well-suited for gene therapy since it is caused by a mutation in single gene which only affects one body system (the hematopoietic system). Viruses have been used to deliver a normal gp91 gene to rats with a mutation in this gene, and subsequently the phagocytes in these rats were able to produce oxygen radicals. In 2006, two human patients with X-linked chronic granulomatous disease underwent gene therapy and blood cell precursor stem cell