Patrick Bouvier Kennedy Patrick Bouvier Kennedy Patrick Bouvier Kennedy (August 7, 1963 – August 9, 1963) was the infant child of United States President John F. Kennedy and First Lady Jacqueline Kennedy. He was the younger brother of Caroline and John Jr.; another daughter was stillborn. Born prematurely, Kennedy lived just over 39 hours before desperate attempts to save him failed, putting the First Family and nation into mourning. Three months later, his death was eclipsed by his father's assassination, but the Kennedy infant's death brought hyaline membrane disease (HMD) into the public consciousness and inspired further research. In August 1963, the 34-year-old
Caroline of Ansbach physics discussion of the 18th century. She helped to popularise the practice of variolation (an early type of immunisation), which had been witnessed by Lady Mary Wortley Montagu and Charles Maitland in Constantinople. At the direction of Caroline, six condemned prisoners were offered the chance to undergo variolation instead of execution: they all survived, as did six orphan children given the same treatment as a further test. Convinced of its medical value, Caroline had her children Amelia, Caroline and Frederick inoculated against smallpox in the same manner. In praising her support for smallpox inoculation, Voltaire wrote of her, "I must