Aphthous stomatitis countries. Within nations, it is more common in higher socioeconomic groups. Males and females are affected in an equal ratio, and the peak age of onset between 10 and 19 years. About 80% of people with aphthous stomatitis first developed the condition before the age of 30. There have been reports of ethnic variation. For example, in the United States, aphthous stomatitis may be three times more common in white-skinned people than black-skinned people. "Aphthous affectations" and "aphthous ulcerations" of the mouth are mentioned several times in the treatise "Of the Epidemics" (part of the Hippocratic corpus, in the 4th
Medicine in ancient Rome the initial object that allowed the stabilization of these humours. By contrast, drugs, venesection, cautery and surgery were drastic and were to be used only when diet could no longer help. The survival and amendment of Hippocratic medicine is attributed to Galen. He writes that a physician "must be skilled at reasoning about the problems presented to him, must understand the nature and function of the body within the physician world and must "practice temperance and despise all money". The ideal physician treats both the poor and elite fairly and is a student of all that affects health. Galen references