Anna Morandi Manzolini in 1755 in the scientific knowledge of human anatomy as well as the accurate demonstration of anatomy in wax sculpture. During her famed household lectures on anatomy given before medical practitioners and grand tourists alike, she imparted expert knowledge of empirical anatomy derived from the dissection of, by her own account, of more than 1,000 cadavers, as well as of anatomical discoveries the couple and she alone made. She clearly demonstrated, both theoretically and practically, the wonderful structure of the human body. She also crafted two portrait busts in wax, both of which are currently on display at the Palazzo
Internal medicine diagnosis and management, by careful bedside study of the natural history of diseases and their treatment. Sydenham eschewed dissection of corpses and scrutiny of the internal workings of the body, for considering the internal mechanisms and causes of symptoms. It was thus subsequent to the 17th century that there was a rise in anatomical pathology and laboratory studies, with Giovanni Battista Morgagni, an Italian anatomist of the 18th century, being considered the father of anatomical pathology. Laboratory investigations became increasingly significant, with contribution of doctors including German physician and bacteriologist Robert Koch in the 19th century. The 19th century saw