Mescaline Mescaline is legal only for certain religious groups (such as the Native American Church) and in scientific and medical research. In 1990, the Supreme Court ruled that the state of Oregon could ban the use of mescaline in Native American religious ceremonies. The Religious Freedom Restoration Act (RFRA) in 1993 allowed the use of peyote in religious ceremony, but in 1997, the Supreme Court ruled that the RFRA is unconstitutional when applied against states. Many states, including the state of Utah, have legalized peyote usage with "sincere religious intent", or within a religious organization, regardless of race. While mescaline-containing cacti
Mescaline so contemporary users will often grind it into a powder and pour it in capsules to avoid having to taste it. The usual human dosage is 200–400 milligrams of mescaline sulfate or 178–356 milligrams of mescaline hydrochloride. The average button contains about 25 mg mescaline. Mescaline was first isolated and identified in 1897 by the German chemist Arthur Heffter and first synthesized in 1918 by Ernst Späth. In 1955, English politician Christopher Mayhew took part in an experiment for BBC's "Panorama", in which he ingested 400 mg of mescaline under the supervision of psychiatrist Humphry Osmond. Though the recording was