Adult polyglucosan body disease body disease do not have identified mutations in the "GBE1" gene. In these individuals, the cause of the disease is unknown. Along with evaluation of the symptoms and a neurological examination, a diagnosis can be made based on genetic testing. Whether or not a person is making sufficient amounts of functional glycogen branching enzyme can be determined by taking a skin biopsy and testing for activity of the enzyme. Examination of tissue biopsied from the sural nerve under a microscope can reveal the presence of polyglucosan bodies. There will also be white matter changes visible in a magnetic resonance imaging
Sexual selection in humans their beauty or fine plumages, and that the artistic faculties in humans belong to their spiritual nature and therefore cannot be connected to natural selection, which only affects the animal nature. Darwin was accused of looking to the evolution of early human ancestors through the moral codes of the 19th century Victorian society. Joan Roughgarden, citing elements of sexual behavior in animals and humans that cannot be explained by the sexual-selection model, suggested that the function of sex in human evolution was primarily social. Joseph Jordania suggested in 2011 that in explaining such human morphological and behavioral characteristics as singing,