Stomatitis washes away antigens and acts as a barrier. The oral mucosa is also more vascular (has a better blood supply) than skin, meaning that any antigens are more quickly removed from the area by the circulation. Finally, there is substantially less keratin in oral mucosa, meaning that there is less likelihood that haptens will form. Allergic contact stomatitis appears as non-specific inflammation, so it may be mistaken for chronic physical irritation. There may be burning or soreness of the mouth and ulceration. Chronic exposure to the allergen may result in a lichenoid lesion. Plasma cell gingivitis may also occur, which
History of medicine in the Philippines Rodrigo de San Miguel's "Manual de Medicina Domestica" (Manual on Domestic Medicine), and Fr. Manuel Vilches' "Manuel del Mediquillo Visaya" (Manuel of the Visayan Traditional Healers). Philippine National Artist and painter Carlos "Botong" V. Francisco recorded and depicted the history of medicine in the Philippines by creating four mural-like four-panel oil paintings collectively titled "The Progress of Medicine in the Philippines", which traced the practice of medicine from the times of the "babaylans" ("medicine men and women") up to a period in the modern-day era. The first painting depicts pre-colonial medicine, the second portrays medicine during the Spanish colonial period,