Bovine papular stomatitis humans. Bovine papular stomatitis Bovine papular stomatitis is a disease caused by a virus of the family "Poxviridae" and the genus "Parapoxvirus". It occurs worldwide in cattle. Symptoms include reddish, raised, sometimes ulcerative lesions on the lips, muzzle, and in the mouth. It usually occurs before the age of two years. Reinfection is possible because of the short duration of immunity. Clinically, the disease is mild, but its importance lies in the need to differentiate it from foot-and-mouth disease. There have been reports of both lesions on the hands of milkers and similar infections in sheep and goats, as well
Aphthous stomatitis vitamin supplements only infrequently improve the ulceration. The relationship to vitamin B12 deficiency has been the subject of many studies. Although these studies found that 0–42% of those with recurrent ulcers suffer from vitamin B12 deficiency, an association with deficiency is rare. Even in the absence of deficiency, vitamin B12 supplementation may be helpful due to unclear mechanisms. Hematinic deficiencies can cause anemia, which is also associated with aphthous-like ulceration. Gastrointestinal disorders are sometimes associated with aphthous-like stomatitis, e.g. most commonly Celiac disease, but also inflammatory bowel disease such as Crohn's disease or ulcerative colitis. The link between gastrointestinal disorders