Trimethoxyamphetamine Trimethoxyamphetamine TMAs, also known as trimethoxyamphetamines, are a family of isomeric psychedelic hallucinogenic drugs. There exist six different TMAs that differ only in the position of the three methoxy groups: TMA, TMA-2, TMA-3, TMA-4, TMA-5, and TMA-6. The TMAs are analogs of the phenethylamine cactus alkaloid mescaline. The TMAs are substituted amphetamines, however, their action does not resemble that of the unsubstituted compound "amphetamine", which is a stimulant and not a psychedelic. It is reported that some TMA's elicit a range of emotions ranging from sadness to empathy and euphoria. TMA was first synthesized by Hey, in 1947. Synthesis data
Mescaline experiences but they manifest more clearly with eyes closed and under low lighting conditions. Mescaline may cause Hallucinogen persisting perception disorder. As with LSD, synesthesia can occur especially with the help of music. An unusual but unique characteristic of mescaline use is the "geometricization" of three-dimensional objects. The object can appear flattened and distorted, similar to the presentation of a Cubist painting. Mescaline elicits a pattern of sympathetic arousal, with the peripheral nervous system being a major target for this substance. Mescaline is produced when products of natural mammalian catecholamine-based neuronal signalling such as dopamine and noradrenaline are subjected to