Anna Morandi Manzolini in 1755 in the scientific knowledge of human anatomy as well as the accurate demonstration of anatomy in wax sculpture. During her famed household lectures on anatomy given before medical practitioners and grand tourists alike, she imparted expert knowledge of empirical anatomy derived from the dissection of, by her own account, of more than 1,000 cadavers, as well as of anatomical discoveries the couple and she alone made. She clearly demonstrated, both theoretically and practically, the wonderful structure of the human body. She also crafted two portrait busts in wax, both of which are currently on display at the Palazzo
Anna Morandi Manzolini children. In 1755, her husband died, and she was left with very slender means of support. She received tempting offers from other universities, but she preferred to remain in her native city, Bologna. She closed a laborious and honored life in the city in 1774, at the age of 60 years. When her husband became ill with tuberculosis, she received special permission to lecture in his place. She became professor of anatomy upon his death in 1755. Knowledge of her talent in molding anatomical models spread throughout Europe and she was invited to the court of Catherine II of Russia