Mescaline of the genus "Echinopsis" are technically controlled substances under the Controlled Substances Act, they are commonly sold publicly as ornamental plants. In the United Kingdom, mescaline in purified powder form is a Class A drug. However, dried cactus can be bought and sold legally. Mescaline is considered a schedule 9 substance in Australia under the Poisons Standard (October 2015). A schedule 9 substance is classified as "Substances with a high potential for causing harm at low exposure and which require special precautions during manufacture, handling or use. These poisons should be available only to specialised or authorised users who have
Mescaline a few days. Mescaline causes cross-tolerance with other serotonergic psychedelics such as LSD and psilocybin. About half the initial dosage is excreted after 6 hours, but some studies suggest that it is not metabolized at all before excretion. Mescaline appears not to be subject to metabolism by CYP2D6 and between 20% and 50% of mescaline is excreted in the urine unchanged, and the rest being excreted as the carboxylic acid form of mescaline, a likely result of MAO degradation. The LD of mescaline has been measured in various animals: 212 mg/kg i.p. (mice), 132 mg/kg i.p. (rats), and 328 mg/kg