Aphthous stomatitis countries. Within nations, it is more common in higher socioeconomic groups. Males and females are affected in an equal ratio, and the peak age of onset between 10 and 19 years. About 80% of people with aphthous stomatitis first developed the condition before the age of 30. There have been reports of ethnic variation. For example, in the United States, aphthous stomatitis may be three times more common in white-skinned people than black-skinned people. "Aphthous affectations" and "aphthous ulcerations" of the mouth are mentioned several times in the treatise "Of the Epidemics" (part of the Hippocratic corpus, in the 4th
Aphthous stomatitis aphthae, (recurrent) aphthous ulceration and (oral) aphthosis. In traditional Chinese medicine, claimed treatments for aphthae focus on clearing heat and nourishing Yin. Rembrandt Gentle White toothpaste did not contain sodium lauryl sulfate, and was specifically marketed as being for the benefit of "canker sore sufferers". When the manufacturer Johnson & Johnson discontinued the product in 2014, it caused a backlash of anger from long term customers, and the toothpaste began to sell for many times the original price on the auction website eBay. Aphthous stomatitis Aphthous stomatitis is a common condition characterized by the repeated formation of benign and non-contagious