Mescaline Mescaline Mescaline (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic alkaloid of the phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. It occurs naturally in the peyote cactus ("Lophophora williamsii"), the San Pedro cactus ("Echinopsis pachanoi"), the Peruvian torch ("Echinopsis peruviana"), and other members of the Cactaceae plant family. It is also found in small amounts in certain members of the Fabaceae (bean) family, including "Acacia berlandieri". However those claims concerning Acacia species have been challenged and have been unsupported in additional analysis. Peyote has been used for at least 5,700 years by Native Americans in
NBOMe-mescaline psychedelic drug at some unspecified point prior. It first became available as a commodity in the research chemical market in May 2010 several months after a few 25x-NBOMes became available. Solubility of the hydrochloride salt: ~5 mg/ml in Phosphate Buffered Saline (PBS) @ pH 7.2; ~10 mg/ml in ethanol & DMF; ~20 mg/ml in DMSO. NBOMe-mescaline can be synthesized from mescaline and 2-methoxybenzaldehyde, via reductive alkylation. That can be done stepwise by first making the imine and then reducing the formed imine with sodium borohydride, or by direct reaction with sodium triacetoxyborohydride. An alternative production method which removes the need