Aphthous stomatitis caused by a reduction in numbers of CD4+ T cells may be implicated in RAS-type ulceration in HIV infection. The thickness of the mucosa may be an important factor in aphthous stomatitis. Usually, ulcers form on the thinner, non-keratinizing mucosal surfaces in the mouth. Factors which decrease the thickness of the mucosa increase the frequency of occurrence, and factors which increase the thickness of the mucosa correlate with decreased ulceration. The nutritional deficiencies associated with aphthous stomatitis (Vitamin B12, folate, and iron) can all cause a decrease in the thickness of the oral mucosa (atrophy). Local trauma is also associated
Tropical medicine children under 5 fell by an estimated 35%. Tuberculosis (TB) is an infectious bacterial disease that can affect any part of the body, though it primarily affects the lungs. It is a disease that affects the poor and weak, and is far more common in developing countries. TB can either be in its latent or active form. TB can be latent for years, sometimes over a decade. Though TB research receives a mere 1/6th the funding of HIV research, the disease has killed more people in the last 200 years than any other infectious disease. According to the Liverpool School