Susan C. Baker throughout the body. This disease also affects skin, mucous membranes, and the body's lymph nodes. Baker's lab is investigating the possibility of a viral causative agent for the disease. This disease mostly affects children under the age of 5. Causes remain unknown, however it is treatable within days if the symptoms are recognized early enough. If left untreated, it can lead to serious problems for the heart. Baker has also worked closely with coronaviruses, the causative agent of Severe Acute Respiratory Syndrome. These are viruses that affect mostly the upper respiratory and GI tract of humans and are named because
Glycogen storage disease type II Glycogen storage disease type II Glycogen storage disease type II, also called Pompe disease, is an autosomal recessive metabolic disorder which damages muscle and nerve cells throughout the body. It is caused by an accumulation of glycogen in the lysosome due to deficiency of the lysosomal acid alpha-glucosidase enzyme. It is the only glycogen storage disease with a defect in lysosomal metabolism, and the first glycogen storage disease to be identified, in 1932 by the Dutch pathologist J. C. Pompe. The build-up of glycogen causes progressive muscle weakness (myopathy) throughout the body and affects various body tissues, particularly in the