3,4-Dimethoxyphenethylamine synthesis of Bevantolol. DMPEA has some activity as a monoamine oxidase inhibitor. DMPEA occurs naturally along with mescaline in various species of cacti such as San Pedro and Peruvian Torch. 3,4-Dimethoxyphenethylamine 3,4-Dimethoxyphenethylamine (DMPEA) is a chemical compound of the phenethylamine class. It is an analogue of the major human neurotransmitter dopamine where the 3- and 4-position hydroxy groups have been replaced with methoxy groups. It is also closely related to mescaline which is 3,4,5-trimethoxyphenethylamine. One of the earliest syntheses of DMPEA (then referred to as "homoveratrylamine") was that of Pictet and Finkelstein, who made it in a multi-step sequence starting
NBOMe-mescaline psychedelic drug at some unspecified point prior. It first became available as a commodity in the research chemical market in May 2010 several months after a few 25x-NBOMes became available. Solubility of the hydrochloride salt: ~5 mg/ml in Phosphate Buffered Saline (PBS) @ pH 7.2; ~10 mg/ml in ethanol & DMF; ~20 mg/ml in DMSO. NBOMe-mescaline can be synthesized from mescaline and 2-methoxybenzaldehyde, via reductive alkylation. That can be done stepwise by first making the imine and then reducing the formed imine with sodium borohydride, or by direct reaction with sodium triacetoxyborohydride. An alternative production method which removes the need