Aphthous stomatitis with aphthous stomatitis, and it is known that trauma can decrease the mucosal barrier. Trauma could occur during injections of local anesthetic in the mouth, or otherwise during dental treatments, frictional trauma from a sharp surface in the mouth such as broken tooth, or from tooth brushing. Hormonal factors are capable of altering the mucosal barrier. In one study, a small group of females with aphthous stomatitis had fewer occurrences of aphthous ulcers during the luteal phase of the menstrual cycle or with use of the contraceptive pill. This phase is associated with a fall in progestogen levels, mucosal proliferation
Medicine in ancient Rome the initial object that allowed the stabilization of these humours. By contrast, drugs, venesection, cautery and surgery were drastic and were to be used only when diet could no longer help. The survival and amendment of Hippocratic medicine is attributed to Galen. He writes that a physician "must be skilled at reasoning about the problems presented to him, must understand the nature and function of the body within the physician world and must "practice temperance and despise all money". The ideal physician treats both the poor and elite fairly and is a student of all that affects health. Galen references