Independence of Panama from Spain Panama would lead to commerce opportunities. In 1819 the Scotsman Gregor MacGregor led a failed attempt to free Panama. When South American revolutionary zeal deposed Viceroyalty of New Granada Juan de la Cruz Mourgeón, he fled to Panama and was declared governor. Mourgeón was ordered to Ecuador to fight the separatists and appointed José de Fábrega as his successor. As soon as Mourgeón sailed, Fábrega seized the moment for Panama's independence. On 10 November 1821, the first call for independence was made in the small provincial town of Villa de los Santos. Called the ""Primer Grito de Independencia de la
Separation of Panama from Colombia under Tomás de Herrera. After rejoining Colombia following a 13-month independence, it remained a province which saw frequent rebellious flare-ups, notably the Panama crisis of 1885, which saw the intervention of the United States Navy. During the construction of the Panama canal, the initial attempts by France to construct a sea-level canal across the isthmus were secured through treaty with Colombia; however French cost overruns and corruption in the Panama scandals led to abandonment of the Canal for a decade. During the intervening years, local separatists used the political instability of the Thousand Days' War to agitate for political separation