Aphthous stomatitis scars. Each episode of ulceration usually produces a greater number of ulcers, and the time between attacks is less than seen in minor aphthous stomatitis. Major aphthous ulceration usually affects non keratinized mucosal surfaces, but less commonly keratinized mucosa may also be involved, such as the dorsum (top surface) of the tongue or the gingiva (gums). The soft palate or the fauces (back of the throat) may also be involved, the latter being part of the oropharynx rather than the oral cavity. Compared to minor aphthous ulceration, major aphthae tend to have an irregular outline. Herpetiform ulcers, (also termed stomatitis
History of medicine in the Philippines Rodrigo de San Miguel's "Manual de Medicina Domestica" (Manual on Domestic Medicine), and Fr. Manuel Vilches' "Manuel del Mediquillo Visaya" (Manuel of the Visayan Traditional Healers). Philippine National Artist and painter Carlos "Botong" V. Francisco recorded and depicted the history of medicine in the Philippines by creating four mural-like four-panel oil paintings collectively titled "The Progress of Medicine in the Philippines", which traced the practice of medicine from the times of the "babaylans" ("medicine men and women") up to a period in the modern-day era. The first painting depicts pre-colonial medicine, the second portrays medicine during the Spanish colonial period,