Jacqueline Susann sold. By 2016, the book had sold more than 31 million copies. In 1967, the book was adapted into the film of the same name, starring Barbara Parkins as Anne, Patty Duke as Neely, Sharon Tate as Jennifer, and Susan Hayward as Helen Lawson, the aging Broadway legend. Susann made a cameo appearance as a reporter at the scene of Jennifer North's suicide. "Valley of the Dolls" received scathing reviews, but was a widespread commercial success, becoming the sixth highest-grossing film of its year with $44.4 million at the domestic box office, a huge amount for its time. Susann herself
Jacqueline Susann made publishing history as the first writer to have three consecutive number one novels on the "Times" list. The book was filmed in 1975 by Guy Green as "Jacqueline Susann's Once Is Not Enough", with Kirk Douglas, Alexis Smith, Melina Mercouri, Brenda Vaccaro (in an Oscar-nominated performance), and Deborah Raffin as January. The film, executive-produced by Irving Mansfield, was not a critical favorite, but was a commercial success, grossing $15.7 million (the equivalent of $65.2 million in 2016).) Susann's final work was a novella, "Dolores" (Morrow), a "roman a clef" about Jacqueline Kennedy, originally written for the February 1974 issue