Anna Morandi Manzolini Poggi in Bologna. One is a self-portrait, in which she depicts herself at work dissecting a human brain; the other is of her husband, engaged in similar activity. Her wax models were highly prized while she was alive and long after her death. Some of her anatomical models were so skillfully molded that they were extremely difficult to distinguish from the actual body parts from which they were copied. Furthermore, her acute skill at dissection resulted in her discovery of several previously unknown anatomical parts, including the termination of the oblique muscle of the eye. She held the distinction of
Internal medicine diagnosis and management, by careful bedside study of the natural history of diseases and their treatment. Sydenham eschewed dissection of corpses and scrutiny of the internal workings of the body, for considering the internal mechanisms and causes of symptoms. It was thus subsequent to the 17th century that there was a rise in anatomical pathology and laboratory studies, with Giovanni Battista Morgagni, an Italian anatomist of the 18th century, being considered the father of anatomical pathology. Laboratory investigations became increasingly significant, with contribution of doctors including German physician and bacteriologist Robert Koch in the 19th century. The 19th century saw