Stomatitis cause deficiencies, which in turn causes stomatitis. Examples include tropical sprue. Aphthous stomatitis (canker sores) is the recurrent appearance of mouth ulcers in otherwise healthy individuals. The cause is not completely understood, but it is thought that the condition represents a T cell mediated immune response which is triggered by a variety of factors. The individual ulcers (aphthae) recur periodically and heal completely, although in the more severe forms new ulcers may appear in other parts of the mouth before the old ones have finished healing. Aphthous stomatitis is one of the most common diseases of the oral mucosa, and
Medieval medicine of Western Europe was one of the "leading Italian universities in teaching medicine, identification and treating of diseases and ailments, specializing in autopsies and workings of the body." The most prestigious and famous part of the university is the oldest surviving anatomical theater, in which students studied anatomy by observing their teachers perform public dissections. Surgery was formally taught in Italy even though it was initially looked down upon as a lower form of medicine. The most important figure of the formal learning of surgery was Guy de Chauliac. He insisted that a proper surgeon should have a specific knowledge of the human