3,4-Dimethoxyphenethylamine synthesis of Bevantolol. DMPEA has some activity as a monoamine oxidase inhibitor. DMPEA occurs naturally along with mescaline in various species of cacti such as San Pedro and Peruvian Torch. 3,4-Dimethoxyphenethylamine 3,4-Dimethoxyphenethylamine (DMPEA) is a chemical compound of the phenethylamine class. It is an analogue of the major human neurotransmitter dopamine where the 3- and 4-position hydroxy groups have been replaced with methoxy groups. It is also closely related to mescaline which is 3,4,5-trimethoxyphenethylamine. One of the earliest syntheses of DMPEA (then referred to as "homoveratrylamine") was that of Pictet and Finkelstein, who made it in a multi-step sequence starting
Mescaline so contemporary users will often grind it into a powder and pour it in capsules to avoid having to taste it. The usual human dosage is 200–400 milligrams of mescaline sulfate or 178–356 milligrams of mescaline hydrochloride. The average button contains about 25 mg mescaline. Mescaline was first isolated and identified in 1897 by the German chemist Arthur Heffter and first synthesized in 1918 by Ernst Späth. In 1955, English politician Christopher Mayhew took part in an experiment for BBC's "Panorama", in which he ingested 400 mg of mescaline under the supervision of psychiatrist Humphry Osmond. Though the recording was