Antonio Maria Valsalva sense of smell, but he recognized the prodromal symptoms, in the form of dyslalia, of the disease that would eventually cause his death from stroke at Bologna in 1723. Valsalva was buried in the church of San Giovanni in Monte, Bologna. The Valsalva family donated a collection of dried anatomical specimens to be used for educational purposes to the Institute of Sciences founded in 1711. The wear of this material that followed possibly inspired the work of the Bolognese school of wax modeling and the artists Ercole Lelli and Giovanni and Anna Morandi Manzolini. This new anatomic collection includes models
Internal medicine diagnosis and management, by careful bedside study of the natural history of diseases and their treatment. Sydenham eschewed dissection of corpses and scrutiny of the internal workings of the body, for considering the internal mechanisms and causes of symptoms. It was thus subsequent to the 17th century that there was a rise in anatomical pathology and laboratory studies, with Giovanni Battista Morgagni, an Italian anatomist of the 18th century, being considered the father of anatomical pathology. Laboratory investigations became increasingly significant, with contribution of doctors including German physician and bacteriologist Robert Koch in the 19th century. The 19th century saw