Stomatitis IV (delayed) hypersensitivity reaction that occurs in susceptible atopic individuals when allergens penetrate the skin or mucosa. Allergens, which may be different for different individuals, combine with epithelial-derived proteins, forming haptens which bind with Langerhans cells in the mucosa, which in turn present the antigen on their surface to T lymphocytes, sensitizing them to that antigen and causing them to produce many specific clones. The second time that specific antigen is encountered, an inflammatory reaction is triggered at the site of exposure. Allergic contact stomatitis is less common than allergic contact dermatitis because the mouth is coated in saliva, which
Medicine in ancient Rome the initial object that allowed the stabilization of these humours. By contrast, drugs, venesection, cautery and surgery were drastic and were to be used only when diet could no longer help. The survival and amendment of Hippocratic medicine is attributed to Galen. He writes that a physician "must be skilled at reasoning about the problems presented to him, must understand the nature and function of the body within the physician world and must "practice temperance and despise all money". The ideal physician treats both the poor and elite fairly and is a student of all that affects health. Galen references