Mescaline Mescaline Mescaline (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic alkaloid of the phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. It occurs naturally in the peyote cactus ("Lophophora williamsii"), the San Pedro cactus ("Echinopsis pachanoi"), the Peruvian torch ("Echinopsis peruviana"), and other members of the Cactaceae plant family. It is also found in small amounts in certain members of the Fabaceae (bean) family, including "Acacia berlandieri". However those claims concerning Acacia species have been challenged and have been unsupported in additional analysis. Peyote has been used for at least 5,700 years by Native Americans in
Sodium fluoroacetate brand name. The salt is synthesized by treating sodium chloroacetate with potassium fluoride. Potassium fluoroacetate (as opposed to the commercially manufactured sodium salt) occurs naturally in at least 40 plant species in Australia, Brazil, and Africa. It was first identified in "Dichapetalum cymosum", commonly known as gifblaar (Afrikaans) or poison leaf, by Marais in 1944. As early as 1904, colonists in Sierra Leone used extracts of "Chailletia toxicaria", which also contains fluoroacetic acid or its salts, to poison rats. Several native Australian plant genera contain the toxin, including "Gastrolobium", "Gompholobium", "Oxylobium", "Nemcia", and "Acacia". "Gastrolobium" is a genus of flowering