Stomatitis washes away antigens and acts as a barrier. The oral mucosa is also more vascular (has a better blood supply) than skin, meaning that any antigens are more quickly removed from the area by the circulation. Finally, there is substantially less keratin in oral mucosa, meaning that there is less likelihood that haptens will form. Allergic contact stomatitis appears as non-specific inflammation, so it may be mistaken for chronic physical irritation. There may be burning or soreness of the mouth and ulceration. Chronic exposure to the allergen may result in a lichenoid lesion. Plasma cell gingivitis may also occur, which
Medieval medicine of Western Europe was one of the "leading Italian universities in teaching medicine, identification and treating of diseases and ailments, specializing in autopsies and workings of the body." The most prestigious and famous part of the university is the oldest surviving anatomical theater, in which students studied anatomy by observing their teachers perform public dissections. Surgery was formally taught in Italy even though it was initially looked down upon as a lower form of medicine. The most important figure of the formal learning of surgery was Guy de Chauliac. He insisted that a proper surgeon should have a specific knowledge of the human