Stomatitis IV (delayed) hypersensitivity reaction that occurs in susceptible atopic individuals when allergens penetrate the skin or mucosa. Allergens, which may be different for different individuals, combine with epithelial-derived proteins, forming haptens which bind with Langerhans cells in the mucosa, which in turn present the antigen on their surface to T lymphocytes, sensitizing them to that antigen and causing them to produce many specific clones. The second time that specific antigen is encountered, an inflammatory reaction is triggered at the site of exposure. Allergic contact stomatitis is less common than allergic contact dermatitis because the mouth is coated in saliva, which
Tropical medicine children under 5 fell by an estimated 35%. Tuberculosis (TB) is an infectious bacterial disease that can affect any part of the body, though it primarily affects the lungs. It is a disease that affects the poor and weak, and is far more common in developing countries. TB can either be in its latent or active form. TB can be latent for years, sometimes over a decade. Though TB research receives a mere 1/6th the funding of HIV research, the disease has killed more people in the last 200 years than any other infectious disease. According to the Liverpool School