Wilson's disease liver. It is due to mutations in the "COMMD1" (or "MURR1") gene. Despite this findings, "COMMD1" mutations could not be detected in humans with non-Wilsonian copper accumulation states (such as Indian childhood cirrhosis) to explain their genetic origin. Wilson's disease Wilson's disease is a genetic disorder in which copper builds up in the body. Symptoms are typically related to the brain and liver. Liver related symptoms include vomiting, weakness, fluid build up in the abdomen, swelling of the legs, yellowish skin, and itchiness. Brain related symptoms include tremors, muscle stiffness, trouble speaking, personality changes, anxiety, and seeing or hearing things
John Ritter lost to Kelsey Grammer for playing the title character of "Frasier". Upon accepting his trophy, Grammer's remarks included comments made in tribute and remembrance of Ritter. Ritter's final films, "Bad Santa" and "Clifford's Really Big Movie", along with an episode of "Scrubs" (his character in this series died, as well) and "King of the Hill", were dedicated to his memory. On June 6, 2008, a mural of Ritter painted by Eloy Torrez was dedicated at Hollywood High School. In March 2010, the Thoracic Aortic Disease (TAD) Coalition, in partnership with Yasbeck and the John Ritter Foundation (JRF), announced the creation