Deciduous teeth first teeth seen in the mouth are the mandibular centrals and the last are the maxillary second molars. The primary teeth are made up of central incisors, lateral incisors, canines, first molars, and secondary molars; there is one in each quadrant, making a total of four of each tooth. All of these are gradually replaced with a permanent counterpart except for the primary first and second molars; they are replaced by premolars. The replacement of primary teeth begins around age six, when the permanent teeth start to appear in the mouth, resulting in mixed dentition. The erupting permanent teeth cause
Teeth cleaning supplement toothbrushing and interdental cleaning. These include special toothpicks, oral irrigators, and other devices. A 2015 Cochrane review found insufficient evidence to determine whether the interdental brushing decreases the levels of plaque when compared to flossing. Teeth can be cleaned by scrubbing with a twig instead of a toothbrush. Plant sap in the twig takes the place of toothpaste. In many parts of the world teeth cleaning twigs are used. In the Muslim world the miswak or "siwak" is made from twigs or roots that are said to have an antiseptic effect when used for cleaning teeth. Teeth cleaning (also