Stomatitis cause deficiencies, which in turn causes stomatitis. Examples include tropical sprue. Aphthous stomatitis (canker sores) is the recurrent appearance of mouth ulcers in otherwise healthy individuals. The cause is not completely understood, but it is thought that the condition represents a T cell mediated immune response which is triggered by a variety of factors. The individual ulcers (aphthae) recur periodically and heal completely, although in the more severe forms new ulcers may appear in other parts of the mouth before the old ones have finished healing. Aphthous stomatitis is one of the most common diseases of the oral mucosa, and
Aphthous stomatitis spicy and acidic foods and beverages. Many different topical and systemic medications have been proposed (see table), sometimes showing little or no evidence of usefulness when formally investigated. Some of the results of interventions for RAS may in truth represent a placebo effect. No therapy is curative, with treatment aiming to relieve pain, promote healing and reduce the frequency of episodes of ulceration. In cases of folate deficiency, daily folic acid (vitamin B9) supplements may prevent or reduce aphthous stomatitis reoccurrence. The first line therapy for aphthous stomatitis is topical agents rather than systemic medication, with topical corticosteroids being the