Denture-related stomatitis Denture-related stomatitis Denture-related stomatitis (also termed denture sore mouth, denture stomatitis, chronic atrophic candidiasis, Candida-associated denture induced stomatitis, and denture-associated erythematous stomatitis) is a common condition where mild inflammation and redness of the oral mucous membrane occurs beneath a denture. In about 90% of cases, "Candida" species are involved, which are normally a harmless component of the oral microbiota in many people. Denture-related stomatitis is the most common form of oral candidiasis (a yeast infection of the mouth). It is more common in elderly people, and in those who wear a complete upper denture (a denture which replaces all the
Aphthous stomatitis T cells. Persons with aphthous stomatitis also have circulating lymphocytes which react with peptides 91–105 of heat shock protein 65–60, and the ratio of CD4+ T cells to CD8+ T cells in the peripheral blood of individuals with aphthous stomatitis is decreased. Aphthous stomatitis has been associated with other autoimmune diseases, namely systemic lupus erythematosus and inflammatory bowel diseases. However, common autoantibodies are not detected in most patients, and the condition tends to resolve spontaneously with advancing age rather than worsen. Evidence for the T cell-mediated mechanism of mucosal destruction is strong, but the exact triggers for this process are