Wilson's disease liver. It is due to mutations in the "COMMD1" (or "MURR1") gene. Despite this findings, "COMMD1" mutations could not be detected in humans with non-Wilsonian copper accumulation states (such as Indian childhood cirrhosis) to explain their genetic origin. Wilson's disease Wilson's disease is a genetic disorder in which copper builds up in the body. Symptoms are typically related to the brain and liver. Liver related symptoms include vomiting, weakness, fluid build up in the abdomen, swelling of the legs, yellowish skin, and itchiness. Brain related symptoms include tremors, muscle stiffness, trouble speaking, personality changes, anxiety, and seeing or hearing things
Thermoregulation in humans are impermeable to sweat and thus do not facilitate heat loss through evaporation can actually contribute to heat stress. Adjusting the human body temperature downward has been used therapeutically, in particular, as a method of stabilizing a body following trauma. It has been suggested that adjusting the A1 receptor of the hypothalamus may allow humans to enter a hibernation-like state of reduced body temperature, which could be useful for applications such as long-duration space flight. Humans output from 70 watts to 870 watts, depending on the amount of physical activity undertaken. Thermoregulation in humans As in other mammals, thermoregulation in