CYB5R3 the subsequent disease manifestation have been described. The disease manifests as the accumulation of oxidized Fe+3 in humans. Type I recessive congenital methemoglobinemia (RCM) is characterized by a deficiency of the soluble isoform and manifests as the cyanosis of skin and mucous membranes. In type II, the defect affects both isoforms and thus affects more general tissues such as red blood cells, leukocytes, and all body tissues. This type is associated with mental deficiency and other neurologic symptoms, which may be because the cytochrome b5 system plays a crucial role in the desaturation of fatty acids in the body. One
Frank Ritter (professor) Psychology from the Carnegie-Mellon University. Ritter has received study fellowships from the United States Air Force Office of Scientific Research, and the European Science Foundation's program on Learning in Humans and Machines. Ritter directs The Applied Cognitive Science Lab at Penn State University. He studies cognitive modelling, cognitive architectures, human computer interaction, and learning. His research has been funded by the US Office of Navy Research, the United States Air Force Office of Scientific Research, DARPA, the Defence Evaluation and Research Agency (U.K.), and the U.K. Joint Council Initiative on Cognitive Science and Human Computer Interaction, as well as corporations