J. D. Salinger J. D. Salinger Jerome David Salinger (; January 1, 1919 January 27, 2010) was an American writer known for his widely read novel, "The Catcher in the Rye". Following his early success publishing short stories and "The Catcher in the Rye", Salinger led a very private life for more than a half-century. He published his final original work in 1965 and gave his last interview in 1980. Salinger was raised in Manhattan and began writing short stories while in secondary school. Several were published in "Story" magazine in the early 1940s before he began serving in World War II. In
V(D)J recombination the DNA helix. Following what is known as the 12/23 Rule, gene segments to be recombined are usually adjacent to RSSs of different spacer lengths ("i.e.", one has a "12RSS" and one has a "23RSS"). This is an important feature in the regulation of V(D)J recombination. V(D)J recombination begins when V(D)J recombinase (through the activity of RAG1) binds an RSS flanking a coding gene segment (V, D, or J) and creates a single-strand nick in the DNA between the first base of the RSS (just before the heptamer) and the coding segment. This is essentially energetically neutral (no need for