Aphthous stomatitis century BC), although it seems likely that this was oral ulceration as a manifestation of some infectious disease, since they are described as occurring in epidemic-like patterns, with concurrent symptoms such as fever. Aphthous stomatitis was once thought to be a form of recurrent herpes simplex virus infection, and some clinicians still refer to the condition as "herpes" despite this cause having been disproven. The informal term "canker sore" is sometimes used, mainly in North America, either to describe this condition generally, or to refer to the individual ulcers of this condition, or mouth ulcers of any cause unrelated to
Aphthous stomatitis aphthae, (recurrent) aphthous ulceration and (oral) aphthosis. In traditional Chinese medicine, claimed treatments for aphthae focus on clearing heat and nourishing Yin. Rembrandt Gentle White toothpaste did not contain sodium lauryl sulfate, and was specifically marketed as being for the benefit of "canker sore sufferers". When the manufacturer Johnson & Johnson discontinued the product in 2014, it caused a backlash of anger from long term customers, and the toothpaste began to sell for many times the original price on the auction website eBay. Aphthous stomatitis Aphthous stomatitis is a common condition characterized by the repeated formation of benign and non-contagious