Second Punic War in 217. Moving to southern Italy in 216, Hannibal at Cannae annihilated the largest army the Romans had ever assembled. After the death or imprisonment of 130,000 Roman troops in two years, 40% of Rome's Italian allies defected to Carthage, giving her control over most of southern Italy. Macedon and Syracuse joined the Carthaginian side after Cannae and the conflict spread to Greece and Sicily. From 215–210 the Carthaginian army and navy launched repeated amphibious assaults to capture Roman Sicily and Sardinia but were ultimately repulsed. Against Hannibal's skill on the battlefield, the Romans adopted the Fabian strategy – the
Perusia Perusia The ancient Perusia, now Perugia, first appears in history as one of the 12 confederate cities of Etruria. It is first mentioned in the account of the war of 310 or 309 BC between the Etruscans and the Romans. It took, however, an important part in the rebellion of 295 BC and was reduced, with Vulsinii and Arretium (Arezzo), to seek for peace in the following year. It seems the city was in the Antonii's clientela since this period, as it was said by historians during imperial times. In 216 BC and 205 BC it assisted Rome in the