Serial port ports with pinouts and voltage levels incompatible with RS-232. Inter-operation with RS-232 devices may be impossible as the serial port cannot withstand the voltage levels produced and may have other differences that "lock in" the user to products of a particular manufacturer. Low-cost processors now allow higher-speed, but more complex, serial communication standards such as USB and FireWire to replace RS-232. These make it possible to connect devices that would not have operated feasibly over slower serial connections, such as mass storage, sound, and video devices. Many personal computer motherboards still have at least one serial port, even if accessible
Massively parallel signature sequencing Massively parallel signature sequencing Massive parallel signature sequencing (MPSS) is a procedure that is used to identify and quantify mRNA transcripts, resulting in data similar to serial analysis of gene expression (SAGE), although it employs a series of biochemical and sequencing steps that are substantially different. MPSS is a method for determining expression levels of mRNA by counting the number of individual mRNA molecules produced by each gene. It is "open ended" in the sense that the identity of the RNAs to be measured are not pre-determined as they are with gene expression microarrays. A sample of mRNA are first