Second Punic War in 217. Moving to southern Italy in 216, Hannibal at Cannae annihilated the largest army the Romans had ever assembled. After the death or imprisonment of 130,000 Roman troops in two years, 40% of Rome's Italian allies defected to Carthage, giving her control over most of southern Italy. Macedon and Syracuse joined the Carthaginian side after Cannae and the conflict spread to Greece and Sicily. From 215–210 the Carthaginian army and navy launched repeated amphibious assaults to capture Roman Sicily and Sardinia but were ultimately repulsed. Against Hannibal's skill on the battlefield, the Romans adopted the Fabian strategy – the
History of Macedonia (ancient kingdom) of the Italian peninsula. In 216 BC, Philip V sent a hundred light warships into the Adriatic Sea to attack Illyria, a motion that did not go unnoticed by Rome when Scerdilaidas of the Ardiaean Kingdom appealed to the Romans for aid. Rome responded by sending ten heavy quinqueremes from Roman Sicily to patrol the Illyrian coasts, causing Philip V to reverse course and order his fleet to retreat, averting open conflict for the time being. In 215 BC, at the height of the Second Punic War with the Carthaginian Empire, Roman authorities intercepted a ship off the Calabrian coast