Glaucoma and Greenland. Positive family history is a risk factor for glaucoma. The relative risk of having primary open-angle glaucoma (P.O.A.G.) is increased about two- to four-fold for people who have a sibling with glaucoma. Glaucoma, particularly primary open-angle glaucoma, is associated with mutations in several genes, including "MYOC, ASB10, WDR36, NTF4", "TBK1", and "RPGRIP1", although most cases of glaucoma do not involve these genetic mutations. Normal-tension glaucoma, which comprises one-third of POAG, is also associated with genetic mutations (including "OPA1" and "OPTN" genes). Various rare congenital/genetic eye malformations are associated with glaucoma. Occasionally, failure of the normal third-trimester gestational atrophy
Canine glaucoma Canine glaucoma Canine glaucoma refers to a group of diseases in dogs that affect the optic nerve and involve a loss of retinal ganglion cells in a characteristic pattern. An intraocular pressure greater than is a significant risk factor for the development of glaucoma. Untreated glaucoma in dogs leads to permanent damage of the optic nerve and resultant visual field loss, which can progress to blindness. The group of multifactorial diseases which cause glaucoma in dogs can be divided roughly into three main categories: congenital, primary or secondary. In dogs, most forms of primary glaucoma are the result of a