Bivalirudin Bivalirudin Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a direct thrombin inhibitor (DTI). Chemically, it is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech "Hirudo medicinalis"). Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide. It is a potent and highly specific inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind
Salivary diagnostics screen for multiple agents simultaneously contributing in determining the scope of toxin exposure, thereby providing a quicker fight and diagnosis in the event of pandemic, epidemic and bioterrorism. Salivary diagnostics Salivary diagnostics or Salivaomics is a procedure for testing and maintaining the data for diagnostic purposes. Saliva based hand-held sensors are used to detect and measure proteins and nucleic acids that are present in saliva for diagnosis. Salivary diagnostic technology is showing promise in the detection and monitoring malignancies at early stage and other various health concerns. The advantages of salivary diagnostics includes ease of collection, elimination of fear of