Glaucoma and Greenland. Positive family history is a risk factor for glaucoma. The relative risk of having primary open-angle glaucoma (P.O.A.G.) is increased about two- to four-fold for people who have a sibling with glaucoma. Glaucoma, particularly primary open-angle glaucoma, is associated with mutations in several genes, including "MYOC, ASB10, WDR36, NTF4", "TBK1", and "RPGRIP1", although most cases of glaucoma do not involve these genetic mutations. Normal-tension glaucoma, which comprises one-third of POAG, is also associated with genetic mutations (including "OPA1" and "OPTN" genes). Various rare congenital/genetic eye malformations are associated with glaucoma. Occasionally, failure of the normal third-trimester gestational atrophy
Henneke horse body condition scoring system strenuous work and also may lack lean muscle. Horses with a very high body condition score carry too much weight, which interferes with stamina and biomechanics. Some studies addressed the relationship of body condition score and endurance performance in endurance races. In a study of the 1990 Purina Race of Champions (a 241-km / 150-mile, 2-day endurance race), it was found that the top-7 finishers of the race (i.e. highly competitive horses) had significantly lower body condition scores and marginally less rump fat than horses eliminated for metabolic criteria (i.e. less competitive horses). By contrast, two studies on the Tevis