Second Punic War in 217. Moving to southern Italy in 216, Hannibal at Cannae annihilated the largest army the Romans had ever assembled. After the death or imprisonment of 130,000 Roman troops in two years, 40% of Rome's Italian allies defected to Carthage, giving her control over most of southern Italy. Macedon and Syracuse joined the Carthaginian side after Cannae and the conflict spread to Greece and Sicily. From 215–210 the Carthaginian army and navy launched repeated amphibious assaults to capture Roman Sicily and Sardinia but were ultimately repulsed. Against Hannibal's skill on the battlefield, the Romans adopted the Fabian strategy – the
Ordona economic decline began during the 4th Century BC. The construction of defensive walls during this period suggests a period of battles with other centres in the region, probably comprising clashes with the Greek Hegemonic Cities in the territory, among them neighbouring Taranto. It passed over to the Romans, with the rest of Apulia, after the wars of the Greek-Messapian League, commanded by King Pirro of Epiro (280-275 BC). Herdonia was a protagonist during the Second Punic War (219-202 BC) and in particular, during the events linked to the war's most famous battle at Cannae on 2 August 216 BC. According