Direct cable connection to a standard serial cable) must be used to connect each of the two computers to communicate properly. Such connection uses PPP protocol. If the parallel ports are used, Windows supports standard or basic 4-bit cable (commonly known as LapLink cable), Enhanced Capabilities Port (ECP) cable, or Universal Cable Module (UCM) cable (which was known as DirectParallel cable by Parallel Technologies). Infrared communication ports, like the ones found on laptop computers (such as IrDA), can also be used. Connecting any two computers using USB requires a special proprietary bridge cable. A directly connected pin-to-pin USB type A cable does not
Serial passage found. Notice that relatively few passages are necessary to produce a noticeable change in a virus; for instance, a virus can typically adapt to a new host within ten or so passages. In fact, exactly because serial passage allows for rapid evolution of a virus to its host, it can be used to study the evolution of antibiotic resistance; specifically, for determining what mutations could lead to the development of antibiotic resistance. The technique of serial passage has been around since the 1800s. In particular, Louis Pasteur’s work with the rabies vaccine in the late 1800s exemplifies this method. Pasteur