Legacy-free PC Legacy-free PC A legacy-free PC is a type of personal computer that lacks a floppy drive, legacy ports, and an Industry Standard Architecture (ISA) bus (or sometimes, any internal expansion bus at all). According to Microsoft, "The basic goal for these requirements is that the operating system, devices, and end users cannot detect the presence of the following: ISA slots or devices; legacy floppy disk controller (FDC); and PS/2, serial, parallel, and game ports." The legacy ports are usually replaced with Universal Serial Bus (USB) ports. A USB adapter may be used if an older device must be connected to
Massively parallel signature sequencing Massively parallel signature sequencing Massive parallel signature sequencing (MPSS) is a procedure that is used to identify and quantify mRNA transcripts, resulting in data similar to serial analysis of gene expression (SAGE), although it employs a series of biochemical and sequencing steps that are substantially different. MPSS is a method for determining expression levels of mRNA by counting the number of individual mRNA molecules produced by each gene. It is "open ended" in the sense that the identity of the RNAs to be measured are not pre-determined as they are with gene expression microarrays. A sample of mRNA are first