Glaucoma and Greenland. Positive family history is a risk factor for glaucoma. The relative risk of having primary open-angle glaucoma (P.O.A.G.) is increased about two- to four-fold for people who have a sibling with glaucoma. Glaucoma, particularly primary open-angle glaucoma, is associated with mutations in several genes, including "MYOC, ASB10, WDR36, NTF4", "TBK1", and "RPGRIP1", although most cases of glaucoma do not involve these genetic mutations. Normal-tension glaucoma, which comprises one-third of POAG, is also associated with genetic mutations (including "OPA1" and "OPTN" genes). Various rare congenital/genetic eye malformations are associated with glaucoma. Occasionally, failure of the normal third-trimester gestational atrophy
Henneke horse body condition scoring system to either being overweight or underweight, respectively. Breeding mares with a body condition score less than five have been linked in research to problems with reproduction. The energy demands of milk production for a foal are very high, so most mares will lose condition while lactating. Also, a mare with a body condition score less than five will have more difficulty conceiving. For these reasons, recommendations are for breeding mares to score between 6 and 7. Higher body condition scores have not been shown to affect reproduction but are unhealthy for the horse. Stallions have the best reproductive success at