Marcus Atilius Regulus (consul 227 BC) army of 80,000 Romans and allies was amassed together to smash the Carthaginian army under Hannibal. The historian Polybius records that both he and Servilius died fighting bravely at the Battle of Cannae. However, there was a Marcus Atilius Regulus who was Praetor Urbanus (and later also Peregrinus), but it is thought that this person is actually a textual mis-reading of the name Marcus Aemilius Lepidus. It is unlikely that the aged, former consul would become a Praetor again three years after Cannae. His younger brother Gaius was killed fighting the Gauls at the Battle of Telamon in 225 BC,
Ordona economic decline began during the 4th Century BC. The construction of defensive walls during this period suggests a period of battles with other centres in the region, probably comprising clashes with the Greek Hegemonic Cities in the territory, among them neighbouring Taranto. It passed over to the Romans, with the rest of Apulia, after the wars of the Greek-Messapian League, commanded by King Pirro of Epiro (280-275 BC). Herdonia was a protagonist during the Second Punic War (219-202 BC) and in particular, during the events linked to the war's most famous battle at Cannae on 2 August 216 BC. According