Serial port requiring programs to refer to them by hardware address. Unix-like operating systems usually label the serial port devices /dev/tty*. "TTY" is a common trademark-free abbreviation for "teletype", a device commonly attached to early computers' serial ports, and * represents a string identifying the specific port; the syntax of that string depends on the operating system and the device. On Linux, 8250/16550 UART hardware serial ports are named /dev/ttyS*, USB adapters appear as /dev/ttyUSB* and various types of virtual serial ports do not necessarily have names starting with tty. The DOS and Windows environments refer to serial ports as COM ports:
Serial passage found. Notice that relatively few passages are necessary to produce a noticeable change in a virus; for instance, a virus can typically adapt to a new host within ten or so passages. In fact, exactly because serial passage allows for rapid evolution of a virus to its host, it can be used to study the evolution of antibiotic resistance; specifically, for determining what mutations could lead to the development of antibiotic resistance. The technique of serial passage has been around since the 1800s. In particular, Louis Pasteur’s work with the rabies vaccine in the late 1800s exemplifies this method. Pasteur