Former state routes in Arizona was a state highway in the eastern part of the state of Arizona, starting in the town of Nogales and ending at the New Mexico state line near Gallup on old U.S. Route 66 (presently Interstate 40). The route was cosigned with other routes, including U.S. Route 89 North from Nogales to Tucson, U.S. Route 80/U.S. Route 89 north from Tucson to U.S. Route 60 and U.S. Route 70 at Florence Junction, east on 60/70 to Globe and then 60 past Show Low to State Route 61, then east on 61 to U.S. 666 north of Springerville, where it overlapped
U.S. Route 80 in Arizona road side businesses and attractions, including many iconic motor hotels and restaurants. US 80 was a particularly long highway, reaching a length of almost within the state of Arizona alone. With the advent of the Interstate Highway System, Interstate 10 and Interstate 8 both replaced US 80 within the state. US 80 was removed from Arizona in 1989; the remainder of it now being State Route 80. In September 2018, the Arizona Department of Transportation designated former segments of the highway as Historic U.S. Route 80. On its journey across Arizona, US 80 made two indirect loops to both Phoenix