Bivalirudin Bivalirudin Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a direct thrombin inhibitor (DTI). Chemically, it is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech "Hirudo medicinalis"). Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide. It is a potent and highly specific inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind
Naturally occurring retirement community South Houses, a ten-building 2,800-unit moderate-income housing cooperative located in New York City, with support from the UJA/Federation of New York. Since then, the NORC program model has been broadly replicated at the local, state, and national levels and can be found in more than 25 states across the country. Naturally occurring retirement community A naturally occurring retirement community (NORC; ) is a term used to describe a community that has a large proportion of residents over 60 but was not specifically planned or designed to meet the needs of seniors living independently in their homes. NORCs may develop in