Caduceus eloquence). The caduceus is often incorrectly used as a symbol of healthcare organizations and medical practice, particularly in North America, due to confusion with the traditional medical symbol, the Rod of Asclepius, which has only one snake and is never depicted with wings. It is thought that this symbol's long lasting association with the medical profession stems from early use of twigs to draw out long bodied inter muscular parasitic worms by wrapping them slowly around the twig so as not to break them or allow them to escape back into the body, a successful treatment still in use today,
Transporter associated with antigen processing Transporter associated with antigen processing Transporter associated with antigen processing (TAP) protein complex belongs to the ATP-binding-cassette transporter family. It delivers cytosolic peptides into the endoplasmic reticulum (ER), where they bind to nascent MHC class I molecules. The TAP structure is formed of two proteins: TAP-1 and TAP-2, which have one hydrophobic region and one ATP-binding region each. They assemble into a heterodimer, which results in a four-domain transporter. The TAP transporter is found in the ER lumen associated with the "peptide-loading complex" (PLC). This complex of β2 microglobulin, calreticulin, ERp57, TAP, tapasin, and MHC class I acts to keep