Seymour family V's visit to England in 1522. The eldest of his ten children was Edward Seymour, 1st Duke of Somerset, the famous Protector in the reign of Edward VI; his third son was Thomas Seymour, Baron Seymour of Sudeley; and his eldest daughter Jane was third wife of King Henry VIII, and mother of Edward VI. The Protector was married twice; and, probably owing to the adultery of his first wife whom he repudiated about 1535, his titles and estates were entailed first on the issue of his second marriage with Anne, daughter of Sir Edward Stanhope. The Protector's eldest surviving
Charles Seymour, 6th Duke of Somerset to the dukedom created for and forfeited by his own great-grandfather, Edward Seymour, 1st Duke of Somerset (executed 1552). Three years later, in 1678, Charles's brother, the 5th duke, was murdered in Italy, aged 20, unmarried and without progeny, having been shot at the door of his inn at Lerice. The 16-year-old Charles Seymour became the 6th duke and the 4th Baron Seymour of Trowbridge. In 1682, at the age of 20 he married a great heiress, the 15-year-old Lady Elizabeth Percy (1667–1722), daughter and sole heiress of Joceline Percy, 11th Earl of Northumberland (1644–1670), who brought him immense estates,