Sophia Brahe that Larsdatter worked for Tycho in Denmark, and later for Sophie, who taught her medicine. Larsdatter was variously said to have lived to 123 or 124 years and to have become known for her "miracle plaster". Sophia Brahe Sophia or Sophie Brahe or after marriage Sophie Thott Lange (22 September 1556 or 24 August 1559 – 1643), was a Danish horticulturalist with knowledge of astronomy, chemistry, and medicine. She assisted her brother Tycho Brahe with his astronomical observations. She was born in Knudstrup, as the youngest of ten children, to Otte Brahe "rigsråd," or advisor to the King of Denmark;
Sophia Brahe alchemy experiments, so their marriage was delayed some years while he avoided his debtors and traveled to Germany to try to find patrons for his work. Tycho Brahe wrote the Latin epic poem "Urania Titani" during the couple's separation, expressed as a letter from his sister Sophia to her fiance in 1594. Tycho casts Sophia as Urania, muse of astronomy, a further suggestion of his respect for her scientific endeavours. In 1599, she visited Lange in Hamburg, but they did not marry until 1602 in Eckernförde. They lived in this town for a while in extreme poverty. Sophie wrote a