Sophia Brahe that Larsdatter worked for Tycho in Denmark, and later for Sophie, who taught her medicine. Larsdatter was variously said to have lived to 123 or 124 years and to have become known for her "miracle plaster". Sophia Brahe Sophia or Sophie Brahe or after marriage Sophie Thott Lange (22 September 1556 or 24 August 1559 – 1643), was a Danish horticulturalist with knowledge of astronomy, chemistry, and medicine. She assisted her brother Tycho Brahe with his astronomical observations. She was born in Knudstrup, as the youngest of ten children, to Otte Brahe "rigsråd," or advisor to the King of Denmark;
Tycho Brahe in 1580, taught Count Wilhelm of Kassel and his astronomer Christoph Rothmann to build copies of Brahe's instruments without permission from Brahe. In turn, Craig, who had studied with Wittich, accused Brahe of minimizing Wittich's role in developing some of the trigonometric methods used by Brahe. In his dealings with these disputes, Tycho Brahe made sure to leverage his support in the scientific community, by publishing and disseminating his own answers and arguments. When Frederick died in 1588, his son and heir Christian IV was only 11 years old. A regency council was appointed to rule for the young prince-elect