Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Emerging adulthood and early adulthood for a lifetime relationship partner, so they explore romantically and sexually as there is less parental control. While in the United States during adolescence dating usually occurs in groups and in situations such as parties and dances, in emerging adulthood, relationships last longer and often include sexual relations as well as cohabitation. As far as work, the majority of working adolescents in the United States tend to see their jobs as a way to make money for recreational activities rather than preparing them for a future career. In contrast, 18- to 25-year-olds in emerging adulthood view their jobs as a