Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Forever to Remain radio in 1952. Forever to Remain Forever to Remain is a 1948 novel by E. V. Timms, the first in his Great South Land Saga series of novels. He wrote it intending to be the first in a 12-part series of novels. It is set in West Australia, where Timms had spent some of his childhood. The initial print run was 20,000 copies, which was considered "colossal" in Australian publishing at the time. It was published in Britain as "The Violent Years". In 1831, a ship "London Lass" sails from London to Swan River settlement in Western Australia. Timms adapted