Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Facial symmetry face is evaluated by human brain via the facial recognition process. This fast and effective detection is difficult with computer programs. For instance, the faces that were considered to possess a strong aesthetic appeal were the ones where the conjunction of similar or corresponding facial features were, to some extent, contrasting. Likewise shared features echoism, proportions and similarity to people the person bonded to early in life (prima copulism) have been suggested as relevant. Research indicates that facial symmetry is linked to the 'big-five' model of personality. The most consistent finding is that facial symmetry is positively correlated with extraversion,