Human nose the Japanese invasions of Korea from 1592 to 1598. The septal cartilage can be destroyed through repeated nasal inhalation of drugs such as cocaine. This in turn can lead to more widespread collapse of the nasal skeleton. Nose-picking is a common, mildly taboo habit. Medical risks include the spread of infections, nosebleeds and, rarely, perforation of the nasal septum. When it becomes compulsive it is termed rhinotillexomania. The wiping of the nose with the hand, commonly referred to as the "allergic salute", is also mildly taboo and can result in the spreading of infections as well. Habitual as well as
Cause of obsessive-compulsive disorder Cause of obsessive-compulsive disorder The cause of obsessive-compulsive disorder is concerned with identifying the biological risk factors involved in the expression of obsessive-compulsive disorder (OCD) symptomology. The leading hypotheses propose the involvement of the orbitofrontal cortex, basal ganglia, and/or the limbic system, with discoveries being made in the fields of neuroanatomy, neurochemistry, neuroimmunology, neurogenetics, and neuroethology. Although there has been substantial debate regarding the assessment of DCO, current research has gravitated toward structural and functional neuroimaging. These technological innovations have provided a better understanding of the neuroanatomical risk factors of OCD. These studies can be divided into four basic categories: