Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Emerging adulthood and early adulthood to develop during emerging adulthood, the cognition of emerging adults is an area that receives the majority of attention. Arnett explains, "Emerging adulthood is a critical stage for the emergence of complex forms of thinking required in complex societies." Crucial changes take place in their sense of self and capacity for self-reflection. At this stage, emerging adults often decide on a particular worldview and are able to recognize that other perspectives exist and are valid as well. While cognition generally becomes more complex, education level plays an important role in this development. Not all emerging adults reach the same advanced