Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Emerging adulthood and early adulthood distinct subjectively. Emerging adulthood is the sole age period where there is nothing that is demographically consistent. At this time, adolescents in the United States up to age 20, over 95% live at home with at least one parent, 98% are not married, under 10% have become parents, and more than 95% attend school. Similarly, people in their thirties are also demographically normative: 75% are married, 75% are parents, and under 10% attend school. Residential status and school attendance are two reasons that the period of emerging adulthood is incredibly distinct demographically. Regarding residential status, emerging adults in the United