Orthopedic Foundation for Animals seizures for Standard Poodles through an exclusive agreement with the University of Missouri. The OFA has the largest fully searchable online canine health database in the world, with over 1,000,000 records. Each dog (or cat) who has ever had an OFA certification issued can be searched by name, part of name, or registration number. Results automatically include all OFA certifications for that dog, plus sire, dam, siblings, half-siblings, and offspring. Orthopedic Foundation for Animals The Orthopedic Foundation for Animals (OFA) is a not-for-profit organization based in Columbia, Missouri that aims to research and prevent orthopedic and hereditary diseases in companion
Fund for the Replacement of Animals in Medical Experiments Fund for the Replacement of Animals in Medical Experiments Fund for the Replacement of Animals in Medical Experiments (FRAME) is a charity based in Nottingham, UK. FRAME promotes consideration of the ethical and scientific issues involved in the use of laboratory animals for medical research, and the adoption of the Three Rs strategy of alternatives to animal testing. The Three Rs (Replacement, Reduction, Refinement) strategy was first suggested by zoologist William Russell and microbiologist Rex Burch, with Replacement being the ultimate goal. FRAME campaigns for the replacement of animal testing methods with alternatives that do not use animals. If there