Angular cheilitis and glossitis (inflammation of the tongue). It is not completely understood how iron deficiency causes AC, but it is known that it causes a degree of immunocompromise (decreased efficiency of the immune system) which may in turn allow an opportunistic infection of candida. Vitamin B2 deficiency (ariboflavinosis) may also cause AC, and other conditions such as redness of mucous membranes, magenta colored glossitis (pink inflammation of the tongue). Vitamin B5 deficiency may also cause AC, along with glossitis, and skin changes similar to seborrhoeic dermatitis around the eyes, nose and mouth. Vitamin B12 deficiency is sometimes responsible for AC, and
University of Pennsylvania School of Dental Medicine such areas as oral microbiology and virology, inflammation and immunity, tooth development, and the use of analgesics and sedatives, to the cellular biology of connective tissues and bone, the applications for state-of-the-art dental materials, and the causes and effects of periodontal disease. Interdisciplinary research is a hallmark of the University of Pennsylvania, and Penn Dental Medicine investigators collaborate extensively with faculty throughout the Penn campus. University of Pennsylvania School of Dental Medicine The University of Pennsylvania School of Dental Medicine (often referred to as Penn Dental Medicine or simply Penn Dental) is the dental school of the University of Pennsylvania