Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Facial implant Facial implant Facial implants are used to enhance certain features of the face. The surgery may be elective, or needed as the result of prior surgery on the face. Each involves placing synthetic materials deep under the subcutaneous tissue and onto the underlying bone. A maxillofacial or plastic surgeon uses them to aesthetically improve facial contours, proportion and correct imbalances caused by injury or hereditary traits. However, in cases that require orthognathic osteotomies, those should be done before any implants are considered. In most cases, facial implant surgery is completed on an outpatient basis in a hospital, a surgeon's office