Seymour family V's visit to England in 1522. The eldest of his ten children was Edward Seymour, 1st Duke of Somerset, the famous Protector in the reign of Edward VI; his third son was Thomas Seymour, Baron Seymour of Sudeley; and his eldest daughter Jane was third wife of King Henry VIII, and mother of Edward VI. The Protector was married twice; and, probably owing to the adultery of his first wife whom he repudiated about 1535, his titles and estates were entailed first on the issue of his second marriage with Anne, daughter of Sir Edward Stanhope. The Protector's eldest surviving
Charles Seymour, 6th Duke of Somerset in 1750. He was created Baron Warkworth of Warkworth Castle and Earl of Northumberland, both with special remainder to Smithson; and was created at the same time Baron Cockermouth and Earl of Egremont, with special remainder to Wyndham. (It has always been customary on the creation of a greater peerage title to create at the same time a barony, to be used as a courtesy title for the eldest son). Charles Seymour, 6th Duke of Somerset Charles Seymour, 6th Duke of Somerset (13 August 1662 – 2 December 1748), known by the epithet "The Proud Duke", was a British peer.