Angular cheilitis and glossitis (inflammation of the tongue). It is not completely understood how iron deficiency causes AC, but it is known that it causes a degree of immunocompromise (decreased efficiency of the immune system) which may in turn allow an opportunistic infection of candida. Vitamin B2 deficiency (ariboflavinosis) may also cause AC, and other conditions such as redness of mucous membranes, magenta colored glossitis (pink inflammation of the tongue). Vitamin B5 deficiency may also cause AC, along with glossitis, and skin changes similar to seborrhoeic dermatitis around the eyes, nose and mouth. Vitamin B12 deficiency is sometimes responsible for AC, and
National Farm Medicine Center National Farm Medicine Center The National Farm Medicine Center (NFMC), established in 1981, is a non-profit program in Marshfield, Wisconsin dedicated to agricultural health and safety research, and service. The center is a component of the Marshfield Clinic Research Foundation, which is part of Marshfield Clinic. In the 1960s research was conducted by the Marshfield Clinic Research Foundation on respiratory diseases common in dairy farmers. Dean Emanuel identified maple bark disease among paper mill workers. In 1964, a culture technique developed by Emanuel and Fritz Wenzel to identify the causative agent for "farmer's lung", a chronic, progressive, inflammation in the