Glossitis of the tongue in iron deficiency anemia has been described as diffuse or patchy atrophy with tenderness or burning. One cause of iron deficiency anemia is sideropenic dysphagia (Plummer–Vinson or Paterson–Brown–Kelly syndrome) which is also characterized by esophageal webbing and dysphagia. Pernicious anemia is usually caused by autoimmune destruction of gastric parietal cells. Parietal cells secrete intrinsic factor which is required for the absorption of vitamin B12. Vitamin B12 deficiency results in megaloblastic anemia and may present as glossitis. The appearance of the tongue in vitamin B12 deficiency is described as "beefy" or "fiery red and sore". There may be
Friends of Science in Medicine "there is evidence supporting CAM approaches. You also have to remember that a sizable part of what is done in mainstream medicine lacks robust evidence." Phelps, along with Stephen Myers, a Professor of Complementary Medicine and Director of the Natural Medicine Research Unit at Southern Cross University, in a 2012 editorial in "The Medical Journal of Australia" wrote, "there is great danger for the public if complementary medicine practice is allowed to develop outside mainstream education." They wrote it would undermine "safe practice and critical appraisal", and stated there is now an extensive evidence base for complementary therapies available. In