Glossitis of the tongue in iron deficiency anemia has been described as diffuse or patchy atrophy with tenderness or burning. One cause of iron deficiency anemia is sideropenic dysphagia (Plummer–Vinson or Paterson–Brown–Kelly syndrome) which is also characterized by esophageal webbing and dysphagia. Pernicious anemia is usually caused by autoimmune destruction of gastric parietal cells. Parietal cells secrete intrinsic factor which is required for the absorption of vitamin B12. Vitamin B12 deficiency results in megaloblastic anemia and may present as glossitis. The appearance of the tongue in vitamin B12 deficiency is described as "beefy" or "fiery red and sore". There may be
Institute of Physics and Engineering in Medicine Institute of Physics and Engineering in Medicine The Institute of Physics and Engineering in Medicine (IPEM) is the United Kingdom's professional body and learned society for physicists, engineers and technologists within the field of medicine, founded in 1995, changing its name from the Institution of Physics and Engineering in Medicine and Biology (IPEMB) in 1997. The Institute is governed by an elected Board of Trustees reporting to which are the Science, Research and Innovation Council and the Professional and Standards Council. The councils have operational responsibility for scientific and professional aspects of the Institute's work, respectively. Beneath the councils is