Patella of age. Due to the great stress on the patellofemoral joint during resisted knee flexion, the articular cartilage of the patella is among the thickest in the human body. The lower part of the posterior surface has vascular canaliculi filled and is filled by fatty tissue, the infrapatellar fat pad. Emarginations (i.e. "patella emarginata", a "missing piece") are common laterally on the proximal edge. Bipartite patellas are the result of an ossification of a second cartilaginous layer at the location of an emargination. Previously, bipartite patellas were explained as the failure of several ossification centres to fuse, but this idea
Traditional Chinese medicines derived from the human body were successfully making quasi-empirical preparations of active substances with androgens and estrogens, a technique that modern biochemists did not develop until the early 20th century. The physician William C. Cooper and the sinologist Nathan Sivin (1973) chose what the Chinese call "rényào" 人藥 "human drugs" as a pilot experiment sample for pharmacologically analyzing the efficacy of drugs used in TCM. In contrast to many traditional Chinese plant, animal, and mineral pharmaceuticals with uncertain active constituents, the chemical composition of the human body and parts is well known, and "their therapeutic effectiveness, or lack of it, can be objectively, if approximately,