Glossitis of the tongue in iron deficiency anemia has been described as diffuse or patchy atrophy with tenderness or burning. One cause of iron deficiency anemia is sideropenic dysphagia (Plummer–Vinson or Paterson–Brown–Kelly syndrome) which is also characterized by esophageal webbing and dysphagia. Pernicious anemia is usually caused by autoimmune destruction of gastric parietal cells. Parietal cells secrete intrinsic factor which is required for the absorption of vitamin B12. Vitamin B12 deficiency results in megaloblastic anemia and may present as glossitis. The appearance of the tongue in vitamin B12 deficiency is described as "beefy" or "fiery red and sore". There may be
The Canon of Medicine He began writing the "Canon" in Gorganj, continued in Rey and completed it in Hamadan in 1025. The result was a "clear and ordered "summa" of all the medical knowledge of Ibn Sīnā's time". It served as a more concise reference in contrast to Galen's twenty volumes of medical corpus. "The Canon of Medicine" is divided into five books: Book 1 is made up of six theses which give a general description of medicine in general, the cosmic elements that make up the cosmos and the human body, the mutual interaction of elements (temperaments), fluids of the body (humours), human