Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Adulthood (film) to spend time with her, and makes his way to her flat. He struggles to get there due to all the injuries he received during the past day, though he manages to make it to Lexi's flat, and the two smile as he enters. Adulthood: Music from the Motion Picture was released on 30 June 2008 by Altered Ego. A sequel called "Brotherhood" was released on 29 August 2016. Adulthood (film) Adulthood (stylised as AdULTHOOD) is a 2008 British drama film. It was directed and written by Noel Clarke, who also stars as the protagonist, Sam Peel. Adulthood is a