Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Emerging adulthood and early adulthood emerging adults who have attended college or university have been exposed to and have considered different worldviews, and eventually commit to a worldview that is distinct from the worldview with which they were raised by the end of their college or university career. When Americans between the ages of 18 and 25 are asked whether they believe they have reached adulthood, most do not answer with a "no" or a "yes", but answer with "In some respects yes, in some respects no". It is clear from this ambiguity that most emerging adults in the United States feel they have completed