Facial feminization surgery the lower lip and is at the edges of the chin. Males tend to have a much more prominent Adam's apple than females following puberty. The Adam's apple can be reduced with a procedure called a chondrolaryngoplasty; the goal of the procedure is to reduce the size without leaving a scar. There are risks of damage to the vocal cords and destabilization of the epiglottis. Beautification and rejuvenation procedures are often performed at the same time as facial feminisation. For example, it is common for eye bags and sagging eyelids to be corrected with a procedure called "blepharoplasty" and many
Immunodeficiency–centromeric instability–facial anomalies syndrome Immunodeficiency–centromeric instability–facial anomalies syndrome ICF syndrome (or Immunodeficiency, Centromere instability and Facial anomalies syndrome) is a very rare autosomal recessive immune disorder. It is characterized by variable reductions in serum immunoglobulin levels which cause most ICF patients to succumb to infectious diseases before adulthood. ICF syndrome patients exhibit facial anomalies which include hypertelorism, low-set ears, epicanthal folds and macroglossia. ICF syndrome can be caused by a mutation in the DNA-methyltransferase-3b ("Dnmt3b") gene, located on chromosome 20q11.2. The disease is inherited in an autosomal recessive manner. For ICF patients the most diffused therapy consists of repeated intravenous infusions of immunoglobulins for