A Cure for Serpents A Cure for Serpents A Cure for Serpents: A Doctor in Africa is a 1955 travel book by Alberto Denti di Pirajno, later the Duke of Pirajno, an Italian doctor, writer and former colonial governor of Tripoli. Set in Libya, Ethiopia and Somaliland, the book is a collection of anecdotes about various places he visited in his work as a physician in North Africa in the 1920s and the people he met, which includes tribal chieftains, Berber princes, courtesans and Tuareg tribesmen and of a lioness, which became part pet and part guard. The book was translated into English in
Transporter associated with antigen processing Transporter associated with antigen processing Transporter associated with antigen processing (TAP) protein complex belongs to the ATP-binding-cassette transporter family. It delivers cytosolic peptides into the endoplasmic reticulum (ER), where they bind to nascent MHC class I molecules. The TAP structure is formed of two proteins: TAP-1 and TAP-2, which have one hydrophobic region and one ATP-binding region each. They assemble into a heterodimer, which results in a four-domain transporter. The TAP transporter is found in the ER lumen associated with the "peptide-loading complex" (PLC). This complex of β2 microglobulin, calreticulin, ERp57, TAP, tapasin, and MHC class I acts to keep