Anne Seymour, Duchess of Somerset Anne Seymour, Duchess of Somerset Anne Seymour, Duchess of Somerset (née Stanhope) (c.1510 – 16 April 1587) was the second wife of Edward Seymour, 1st Duke of Somerset (c.1500–1552), who held the office of Lord Protector during the first part of the reign of his nephew King Edward VI, through whom Anne was briefly the most powerful woman in England. During her husband's time as Lord Protector she claimed precedence over the dowager queen Catherine. Anne Stanhope was likely born in 1510, the only child of Sir Edward Stanhope (1462 – 6 June 1511) by his wife Elizabeth Bourchier (b.
Edward Seymour, 1st Duke of Somerset to throw off the Protector within two years and "bear rule as other kings do"; but Edward, schooled to defer to the Council, failed to co-operate. In April 1547, using Edward's support to circumvent Somerset's opposition, Thomas Seymour secretly married Henry VIII's widow Catherine Parr, whose Protestant household included the 11-year-old Lady Jane Grey and the 13-year-old Princess Elizabeth. In summer 1548, a pregnant Catherine Parr discovered Thomas Seymour embracing Princess Elizabeth. As a result, Elizabeth was removed from Catherine Parr's household and transferred to Sir Anthony Denny's. That September, Catherine Parr died in childbirth, and Thomas Seymour promptly resumed