Caduceus as a symbol of medicine a review of 257 of the works bearing this printer's device only one was related to medicine. Similar use of the caduceus in printers' marks continues to the present day, with companies including F. A. Davis Company still using the symbol as an element of their insignia. There are a few other examples of use in this period. It may have been used as a symbol by Sir William Butts, physician to Henry VIII. Similarly, physician John Caius, founder of Caius College, Cambridge, and at the time President of the Royal College of Physicians, during official visits to his eponymous
Transporter associated with antigen processing Transporter associated with antigen processing Transporter associated with antigen processing (TAP) protein complex belongs to the ATP-binding-cassette transporter family. It delivers cytosolic peptides into the endoplasmic reticulum (ER), where they bind to nascent MHC class I molecules. The TAP structure is formed of two proteins: TAP-1 and TAP-2, which have one hydrophobic region and one ATP-binding region each. They assemble into a heterodimer, which results in a four-domain transporter. The TAP transporter is found in the ER lumen associated with the "peptide-loading complex" (PLC). This complex of β2 microglobulin, calreticulin, ERp57, TAP, tapasin, and MHC class I acts to keep