Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Leave to Remain (album) the same venue "Drowned In Sound" suggested the album "is captivating, even if it's not all that it could be" with "Popmatters" review concluding that it's "an album that is extremely hard to get out of one's head indeed". and "The Guardian" chiming 'both beautiful and intense, her best album yet' Leave to Remain (album) Leave to Remain is the sixth studio album by Kathryn Williams released on CAW Records on 1 October 2006. It was her first to feature Kate St John who would produce her next solo album, "The Quickening", in 2010. The track 'Stevie' on the album