Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Facial composite Facial composite A facial composite is a graphical representation of one or more eyewitnesses' memory of a face, as recorded by a composite artist. Facial composites are used mainly by police in their investigation of (usually serious) crimes. These images are also used to reconstruct the suspect's face in hope of identifying them. Construction of the composite was originally performed by a trained artist, through drawing, sketching, or painting, in consultation with a witness or crime victim. Subsequently, techniques were devised for use by those less artistically skilled, employing interchangeable templates of separate facial features. The first such mechanical system,