Sophia Brahe Sophia Brahe Sophia or Sophie Brahe or after marriage Sophie Thott Lange (22 September 1556 or 24 August 1559 – 1643), was a Danish horticulturalist with knowledge of astronomy, chemistry, and medicine. She assisted her brother Tycho Brahe with his astronomical observations. She was born in Knudstrup, as the youngest of ten children, to Otte Brahe "rigsråd," or advisor to the King of Denmark; and Beate Bille Brahe, leader of the royal household for Queen Sophie. Sophia's oldest brother was astronomer Tycho Brahe. Though he was both more than a decade her senior and raised in a separate household, the
Tycho Brahe autopsy performed after his body was exhumed in 1901, and the 20th-century medical assessment is that his death is more likely to have resulted from uremia. The investigations in the 1990s have suggested that Tycho may not have died from urinary problems, but instead from mercury poisoning. It was speculated that he had been intentionally poisoned. The two main suspects were his assistant, Johannes Kepler, whose motives would be to gain access to Brahe's laboratory and chemicals, and his cousin, Erik Brahe, at the order of friend-turned-enemy Christian IV, because of rumors that Tycho had had an affair with Christian's