Sophia Brahe that Larsdatter worked for Tycho in Denmark, and later for Sophie, who taught her medicine. Larsdatter was variously said to have lived to 123 or 124 years and to have become known for her "miracle plaster". Sophia Brahe Sophia or Sophie Brahe or after marriage Sophie Thott Lange (22 September 1556 or 24 August 1559 – 1643), was a Danish horticulturalist with knowledge of astronomy, chemistry, and medicine. She assisted her brother Tycho Brahe with his astronomical observations. She was born in Knudstrup, as the youngest of ten children, to Otte Brahe "rigsråd," or advisor to the King of Denmark;
Tycho Brahe until his coronation in 1596. The head of the council (Steward of the Realm) was Christoffer Valkendorff, who disliked Tycho Brahe after a conflict between them, and hence Tycho's influence at the Danish court steadily declined. Feeling that his legacy on Hven was in peril, he approached the Dowager Queen Sophie and asked her to affirm in writing her late husband's promise to endow Hven to Tycho's heirs. Nonetheless, he realized that the young king was more interested in war than in science, and was of no mind to keep his father's promise. King Christian IV followed a policy of