Little Jack Horner in the Tudor period. The song’s most common lyrics are: <poem style="margin-left:24px> Little Jack Horner Sat in the corner, Eating his Christmas pie; He put in his thumb, And pulled out a plum, And said, "What a good boy am I!"</poem> It was first documented in full in the nursery rhyme collection "Mother Goose's melody, or, Sonnets for the cradle", which may date from 1765, although the earliest surviving English edition is from 1791. The melody commonly associated with the rhyme was first recorded by the composer and nursery rhyme collector James William Elliott in his "National Nursery Rhymes and
(S)-canadine synthase (S)-canadine synthase In enzymology, a (S)-canadine synthase () is an enzyme that catalyzes the chemical reaction The 4 substrates of this enzyme are (S)-tetrahydrocolumbamine, NADPH, H, and O, whereas its 3 products are (S)-canadine, NADP, and HO. This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O with NADH or NADPH as one donor, and the other dehydrogenated. The systematic name of this enzyme class is (S)-tetrahydrocolumbamine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming). Other names in common use include (S)-tetrahydroberberine synthase,