Felidae the Felidae, grouped according to the traditional phenotypical classification with the corresponding genotypical lineages indicated. It includes all of the currently living cat species. There is considerable variation in the taxonomy used for the wildcat. It used to be regarded as "Felis silvestris" with distinct subspecies "F. s. silvestris", "F. s. lybica" and "F. s. ornata" in Europe, Africa and Asia respectively. Since 2017, the IUCN Cat Specialist Group recognises "silvestris" and "lybica" as distinct species. The phylogenetic relationships of extant felids are shown in the following cladogram, based on the molecular phylogenetic analysis of Johnson et al. (2006). The
Fund for the Replacement of Animals in Medical Experiments Fund for the Replacement of Animals in Medical Experiments Fund for the Replacement of Animals in Medical Experiments (FRAME) is a charity based in Nottingham, UK. FRAME promotes consideration of the ethical and scientific issues involved in the use of laboratory animals for medical research, and the adoption of the Three Rs strategy of alternatives to animal testing. The Three Rs (Replacement, Reduction, Refinement) strategy was first suggested by zoologist William Russell and microbiologist Rex Burch, with Replacement being the ultimate goal. FRAME campaigns for the replacement of animal testing methods with alternatives that do not use animals. If there