Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Adulthood (film) Adulthood (film) Adulthood (stylised as AdULTHOOD) is a 2008 British drama film. It was directed and written by Noel Clarke, who also stars as the protagonist, Sam Peel. Adulthood is a sequel to the 2006 film "Kidulthood", which Clarke also wrote, and depicts Peel's experiences after he is released from jail. It grossed £1,203,319 at the UK Box Office during its opening weekend, ranking above "The Incredible Hulk", "Indiana Jones and the Kingdom of the Crystal Skull" and "Sex and the City". After starring in the film, Adam Deacon decided to write and star in his own urban film, "Anuvahood".