Median rhomboid glossitis longest dimension. Predisposing factors include smoking, denture wearing, use of corticosteroid sprays or inhalers and human immunodeficiency virus (HIV) infection. "Candida" species even in healthy people mainly colonizes the posterior dorsal tongue. Median rhombiod glossitis is thought to be a type of chronic atrophic (or erythematous) candidiasis. Microbiological culture of the lesion usually shows "Candida" mixed with bacteria. The diagnosis is usually made on the clinical appearance, and tissue biopsy is not usually needed. The histologic picture is one of superficial candidal hyphal infiltration and a polymorphonuclear leukocytic inflammatory infiltrate present in the epithelium. The rete ridges are elongated and
The Canon of Medicine He began writing the "Canon" in Gorganj, continued in Rey and completed it in Hamadan in 1025. The result was a "clear and ordered "summa" of all the medical knowledge of Ibn Sīnā's time". It served as a more concise reference in contrast to Galen's twenty volumes of medical corpus. "The Canon of Medicine" is divided into five books: Book 1 is made up of six theses which give a general description of medicine in general, the cosmic elements that make up the cosmos and the human body, the mutual interaction of elements (temperaments), fluids of the body (humours), human