Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Emerging adulthood and early adulthood their child's status as an adult. This process may include gestures such as allowing increased amounts of privacy and extending trust. Granting this recognition assists the increasingly independent offspring in forming a strong sense of identity and exploration at a time when it is most crucial. There is varied evidence regarding the continuity of emerging adults' relationships with parents, although most of the research supports the fact that there is moderate stability. A parent-child relationship of higher quality often results in greater affection and contact in emerging adulthood. Attachment styles tend to remain stable from infancy to adulthood. An initial