Square root any nonnegative number, then the principal square root of −"x" is The right side (as well as its negative) is indeed a square root of −"x", since For every non-zero complex number "z" there exist precisely two numbers "w" such that : the principal square root of "z" (defined below), and its negative. There are two complex numbers that square to a given arbitrary non-zero imaginary number formula_11 with real formula_12 where the two-digit pattern {3, 6} repeats over and over again in the partial denominators. Since , the above is also identical to the following generalized continued fractions: The
Root-mean-square deviation of atomic positions the context of docking, as well as in other methods to study the configuration of ligands when bound to macromolecules. Note that, for the case of ligands (contrary to proteins, as described above), their structures are most commonly not superimposed prior to the calculation of the RMSD. Root-mean-square deviation of atomic positions In bioinformatics, the root-mean-square deviation of atomic positions (or simply root-mean-square deviation, RMSD) is the measure of the average distance between the atoms (usually the backbone atoms) of superimposed proteins. Note that RMSD calculation can be applied to other, non-protein molecules, such as small organic molecules. In the