Seymour family V's visit to England in 1522. The eldest of his ten children was Edward Seymour, 1st Duke of Somerset, the famous Protector in the reign of Edward VI; his third son was Thomas Seymour, Baron Seymour of Sudeley; and his eldest daughter Jane was third wife of King Henry VIII, and mother of Edward VI. The Protector was married twice; and, probably owing to the adultery of his first wife whom he repudiated about 1535, his titles and estates were entailed first on the issue of his second marriage with Anne, daughter of Sir Edward Stanhope. The Protector's eldest surviving
Frances Seymour, Duchess of Somerset thus incurred the Queen's wrath. Essex was executed on 25 February 1601 for allegedly conspiring to murder the Queen. He left behind his wife and small children; Frances was less than two years old at the time. Frances's brother was Robert Devereux, 3rd Earl of Essex, and she had an elder sister, Dorothy. She also had three younger half-siblings from her mother's third marriage in 1603 to Richard Burke, 4th Earl of Clanricarde. These were Honora, Mary and Ulick Burke, 1st Marquess of Clanricarde. On 3 March 1616, Frances married at Drayton Bassett William Seymour, 2nd Duke of Somerset (1588-1660),