Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Facial toning muscle exercising. There are two types of facial toning exercises: active and passive face exercises. Face exercises involves repeated voluntary contractions of certain facial muscle groups. The effectiveness of these facial toning techniques in improving appearance is scientifically unproven. Passive exercising by direct skeletal muscle electrostimulation. In this, flat metal electrodes with a conductive gel are affixed to certain points in the face and electrostimulation causes facial muscle contractions. Facial toning Facial toning, or facial exercise is a type of cosmetic procedure or physical therapy tool which promises to alter facial contours by means of increasing muscle tone, and facial