Sophia Brahe that Larsdatter worked for Tycho in Denmark, and later for Sophie, who taught her medicine. Larsdatter was variously said to have lived to 123 or 124 years and to have become known for her "miracle plaster". Sophia Brahe Sophia or Sophie Brahe or after marriage Sophie Thott Lange (22 September 1556 or 24 August 1559 – 1643), was a Danish horticulturalist with knowledge of astronomy, chemistry, and medicine. She assisted her brother Tycho Brahe with his astronomical observations. She was born in Knudstrup, as the youngest of ten children, to Otte Brahe "rigsråd," or advisor to the King of Denmark;
Tycho Brahe having been unable to marry the woman he loved, many of Tycho's family members disagreed, and many churchmen would continue to hold the lack of a divinely sanctioned marriage against him. Kirsten Jørgensdatter gave birth to their first daughter, Kirstine (named after Tycho's late sister) on 12October 1573. Kirstine died from the plague in 1576, and Tycho wrote a heartfelt elegy for her tombstone. In 1574, they moved to Copenhagen where their daughter Magdalene was born, later the family followed him into exile. Kirsten and Tycho lived together for almost thirty years until Tycho's death. Together, they had eight children,