Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Emerging adulthood and early adulthood 25 years of age where adolescents become more independent and explore various life possibilities. Arnett argues that this developmental period can be isolated from adolescence and young adulthood. Emerging adulthood is a new demographic, is contentiously changing, and some believe that twenty-somethings have always struggled with "identity exploration, instability, self-focus, and feeling in-between". Arnett called this period "roleless role" because emerging adults do a wide variety of activities, but are not constrained by any sort of "role requirements". The developmental theory is highly controversial within the developmental field, and developmental psychologists argue over the legitimacy of Arnett's theories and methods.