Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Facial toning Facial toning Facial toning, or facial exercise is a type of cosmetic procedure or physical therapy tool which promises to alter facial contours by means of increasing muscle tone, and facial volume by promoting muscular hypertrophy, and preventing muscle loss due to aging or facial paralysis. Facial toning and exercise is therefore in part a technique to achieve facial rejuvenation by reducing wrinkles, sagging and expression marks on the face and skin. As a physical therapy, facial toning is used for victims of stroke and forms of facial paralysis such as Bell’s palsy. Facial toning achieves this by performing facial