Jack and Jill (nursery rhyme) and brown paper were a home cure used as a method to draw out bruises on the body. Jack is the most common name used in English-language nursery rhymes and represented an archetypal Everyman hero by the 18th century, while Jill or Gill had come to mean a young girl or a sweetheart by the end of the Middle Ages. However, the woodcut that accompanied the first recorded version of the rhyme showed two boys (not a boy and a girl) and used the spelling Gill not Jill. The true origin of the rhyme is unknown, but there are several
L-methionine (S)-S-oxide reductase participates in methionine metabolism. L-methionine (S)-S-oxide reductase In enzymology, a L-methionine (S)-S-oxide reductase () is an enzyme that catalyzes the chemical reaction The 3 substrates of this enzyme are L-methionine, thioredoxin disulfide, and HO, whereas its two products are L-methionine (S)-S-oxide and thioredoxin. This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is L-methionine:thioredoxin-disulfide S-oxidoreductase. Other names in common use include fSMsr, methyl sulfoxide reductase I and II, acetylmethionine sulfoxide reductase, methionine sulfoxide reductase, L-methionine:oxidized-thioredoxin S-oxidoreductase, methionine-S-oxide reductase, and free-methionine