Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome Branchio-oculo-facial syndrome (BOFS) is a disease that arises from a mutation in the TFAP2A gene. It is a rare autosomal dominant disorder that starts to affect a child's development before birth. Symptoms of this condition include skin abnormalities on the neck, deformities of the ears and eyes, and other distinctive facial features such a cleft lip along with slow growth, mental retardation and premature graying of hair. "Branchio" refers to the branchial arches, also known as the pharyngeal arches, of the affected individual. The branchial arches are structures in the developing embryo that give rise to certain tissues
Emerging adulthood and early adulthood the ages of 18–25. Emerging adults have reached a stage of full hormonal maturity and are fully, physically equipped for sexual reproduction. Emerging adulthood is usually thought of as a time of peak physical health and performance as individuals are usually less susceptible to disease and more physically agile during this period than later stages of adulthood. However, emerging adults are generally more likely to contract sexually transmitted infections, as well as to adopt unhealthy behavioral patterns and lifestyle choices. While many people believe that the brains of emerging adults are fully developed, they are in fact still developing into