Glossitis is usually very painful, and there may be erosions present in the depths of the fissures. Similar fissured lesions which are not associated with HSV, as may occur in fissured tongue, do not tend to be painful. The name comes from the geometric pattern of the fissures which are longitudinal, crossed or branched. It is described as occurring in immunocompromized persons, e.g. who have leukemia. However, the association between herpes simplex and geometric glossitis is disputed by some due to a lack of gold standard techniques for diagnosis of intraoral herpetic lesions, and the high prevalence of asymptomatic viral shedding
The Canon of Medicine He began writing the "Canon" in Gorganj, continued in Rey and completed it in Hamadan in 1025. The result was a "clear and ordered "summa" of all the medical knowledge of Ibn Sīnā's time". It served as a more concise reference in contrast to Galen's twenty volumes of medical corpus. "The Canon of Medicine" is divided into five books: Book 1 is made up of six theses which give a general description of medicine in general, the cosmic elements that make up the cosmos and the human body, the mutual interaction of elements (temperaments), fluids of the body (humours), human