Facial feminization surgery the lower lip and is at the edges of the chin. Males tend to have a much more prominent Adam's apple than females following puberty. The Adam's apple can be reduced with a procedure called a chondrolaryngoplasty; the goal of the procedure is to reduce the size without leaving a scar. There are risks of damage to the vocal cords and destabilization of the epiglottis. Beautification and rejuvenation procedures are often performed at the same time as facial feminisation. For example, it is common for eye bags and sagging eyelids to be corrected with a procedure called "blepharoplasty" and many
SKIV2L always starting soon after birth and commonly requiring parenteral nutrition. In cases which do not require parenteral nutrition an elemental diet and supplemental feeding is required. The majority of "SKIV2L" pathogenic variant harbouring patients are small at birth (<10 centile) and remain growth restricted despite increased nutrition. Hair abnormalities are seen in >90% of patients and are described as woolly, brittle hair that is easily removed. Facial dysmorphisms are found in most patients and become more apparent with age. These include a large forehead, broad base of the nose and hypertelorism. Overall the facial features are described as “coarse”. Liver