The Hangover Part II structure. There needs to be a ticking clock, there needs to be a missed night and there needs to be someone who's gone and a woman who is waiting to get married and a guy who needs to get married." In June 2010, before accepting the Guy Movie of the Year award on the Spike Guys Choice Awards, Phillips announced that there would be a "Hangover 2" and that they were hoping to begin filming around October 15, 2010, for a July 4, 2011 weekend release. In July 2010, it was confirmed that film would indeed be set in Thailand
The Hangover Part II audience was 51 percent female and 41 percent were aged between 18 and 24. On May 27, the film took an additional $30.0 million, dropping only 5 percent from the takings of the previous day and becoming the highest-grossing Friday for a live-action comedy. The three-day (Friday–Sunday) opening weekend accumulated $85,946,294—an average of $23,923 per theater—becoming the highest-grossing opening weekend for a comedy film, replacing "The Simpsons Movie" ($74 million), the highest-grossing opening weekend for a live-action comedy, replacing "Austin Powers in Goldmember" ($73 million), the highest-grossing opening weekend for an R-rated comedy, replacing "Sex and the City" ($79 million)