The Hangover Part II and earlier comments made by Phillips denying such reports were a deliberate case of misdirection. The following month, Bradley Cooper stated he believed the rumors to be true and was looking forward to filming "The Hangover 2" in Thailand. In October 2010, Phillips confirmed that the film would take place in Bangkok and Los Angeles and that Galifianakis, Cooper, Helms and Ken Jeong would be returning. On a budget of $80 million, principal photography began on October 8, 2010, in Ontario, California with the first images of production being released a few days later. It was also reported in October
Hangover research of alcohol hangover is growing rapidly. The Alcohol Hangover Research Group had its inaugural meeting in June 2010 as part of the Research Society on Alcoholism (RSA) 33rd Annual Scientific Meeting in San Antonio, Texas. In 2012, Éduc'alcool, a Quebec-based non-profit organization that aims to educate the public on the responsible use of alcohol, published a report noting hangovers have long-lasting effects that inhibit the drinker's capabilities a full 24 hours after heavy drinking. In 2012, Las Vegas based Hangover Heaven, a mobile hangover treatment clinic, opened along with its Hangover Research Institute, which studies the treatment of hangovers.