Pandemic smallpox was responsible for 300–500 million deaths. As recently as the early 1950s, an estimated 50 million cases of smallpox occurred in the world each year. After successful vaccination campaigns throughout the 19th and 20th centuries, the WHO certified the eradication of smallpox in December 1979. To this day, smallpox is the only human infectious disease to have been completely eradicated, and one of two infectious viruses ever to be eradicated. Historically, measles was prevalent throughout the world, as it is highly contagious. According to the U.S. National Immunization Program, 90% of people were infected with measles by age 15.
Human extinction extinction scenarios described here should make the reader overestimate the likelihood of any probabilities given. However, the effect that is more relevant to common consideration of human extinction is the bias that occurs with estimates from experience, and these are in the opposite direction: When judging from personal experience people who have never heard of or experienced their species become extinct would be expected to dramatically underestimate its likelihood. Sociobiologist E. O. Wilson argued that: "The reason for this myopic fog, evolutionary biologists contend, is that it was actually advantageous during all but the last few millennia of the two