Polyuria Polyuria Polyuria () is excessive or an abnormally large production or passage of urine (greater than 2.5 or 3 L over 24 hours in adults). Frequent urination is usually an accompanying symptom. Increased production and passage of urine may also be termed diuresis. Polyuria often appears in conjunction with polydipsia (increased thirst), though it is possible to have one without the other, and the latter may be a cause or an effect. Psychogenic polydipsia may lead to polyuria. The most common cause of polyuria in both adults and children is uncontrolled diabetes mellitus, which causes osmotic diuresis, when glucose levels
Primary polydipsia number of emerging pharmaceutical treatments for psychogenic polydipsia, although these need further investigation: Lithium was previously used for treatment of PPD as a direct competitive ADH agonist, but is now generally avoided due to its toxic effects on the thyroid and kidneys. It is important to note that the majority of psychotropic drugs (and a good many of other classes) can cause dry mouth as a side effect, but this is not to be confused with true polydipsia in which a dangerous drop in serum sodium will be seen. Although primary polydipsia is usually categorised as psychogenic, there are some