Spinone Italiano because it will not run off in front and leave its human companion struggling to keep up as it prefers the slower pace itself. It can be more than happy in a small yard and does not necessarily need acres of land. The small garden combined with regular walks would suit a Spinone well. In part due to its long beard and lip folds, the Spinone can have a tendency to slobber. Like all purebred dogs, it has its share of health problems, but careful breeding is helping the situation cease. In 2004, The Kennel Club in the United Kingdom
Fibronectin type III domain Fibronectin type III domain The Fibronectin type III domain is an evolutionary conserved protein domain that is widely found in animal proteins. The fibronectin protein in which this domain was first identified contains 16 copies of this domain. The domain is about 100 amino acids long and possesses a beta sandwich structure. Of the three fibronectin-type domains, type III is the only one without disulfide bonding present. Fibronectin domains are found in a wide variety of extracellular proteins. They are widely distributed in animal species, but also found sporadically in yeast, plant and bacterial proteins. ABI3BP; ANKFN1; ASTN2; AXL; BOC;