History of smallpox centuries, the WHO certified the global eradication of smallpox in December 1979. Smallpox is one of two infectious diseases to have been eradicated, the other being rinderpest, which was declared eradicated in 2011. It has been suggested that smallpox was a major component of the Plague of Athens that occurred in 430 BCE, during the Peloponnesian Wars, and was described by Thucydides. Galen's description of the Antonine Plague, which swept through the Roman Empire in 165–180, indicates that it was probably caused by smallpox. Returning soldiers brought the disease home with them to Syria and Italy, where it raged for
Isogenic human disease models targeted cancer therapeutics based upon their individual genetic profile. There are several companies working to address this need, a list of the key players and their technology offering is provided below. Isogenic human disease models Isogenic human disease models are a family of cells that are selected or engineered to accurately model the genetics of a specific patient population, "in vitro". They are provided with a genetically matched 'normal cell' to provide an isogenic system to research disease biology and novel therapeutic agents. They can be used to model any disease with a genetic foundation. Cancer is one such disease