The Hangover Part II an exotic location. That's all I know". In January 2010, Phillips dismissed rumors that Zac Efron would join the cast of "The Hangover 2", though Ed Helms stated that Efron would be a welcomed addition, commenting, "I love that guy. He's actually really funny". In March 2010, Phillips denied reports that the film would take place in Mexico or Thailand stating, "I don't know. There's a lot of rumors. There was rumor also that it was going to Mexico or something and neither are true". Also by March, Galifianakis, Helms, Bradley Cooper, and Justin Bartha completed negotiations and signed deals
The Hangover Part II Phillips raised concerns after he joked that Crystal had become addicted to cigarettes after learning to smoke them for the film. Philips later explained that Crystal never actually held a lit cigarette on the film's set and the smoke was added digitally in post-production. Despite this, PETA protested about Crystal's appearance in the film for use of exotic animals for entertainment purposes and the film does not carry the American Humane Association's disclaimer that "no animals were harmed" since the group was denied set visits. In an interview with "New York" magazine, Ken Jeong responded to criticisms of the character