Spinone Italiano the Spinone descended from the Spanish Pointer, whilst others claim that it was the ancient Russian Setter that is responsible for the breed we know today. An even more popular theory is that Greek traders brought coarse-haired setters to Italy during the height of the Roman empire, where the dogs were then crossed with various others and the modern Spinone eventually emerged. The French claim that the Spinone has descended from crosses of several French pointing breeds, whilst the Italians believe the Spinone is the ancestor of the Wirehaired Pointing Griffon, the German Wirehaired Pointer, and the Pudelpointer. Any one
Fibronectin type III domain Fibronectin type III domain The Fibronectin type III domain is an evolutionary conserved protein domain that is widely found in animal proteins. The fibronectin protein in which this domain was first identified contains 16 copies of this domain. The domain is about 100 amino acids long and possesses a beta sandwich structure. Of the three fibronectin-type domains, type III is the only one without disulfide bonding present. Fibronectin domains are found in a wide variety of extracellular proteins. They are widely distributed in animal species, but also found sporadically in yeast, plant and bacterial proteins. ABI3BP; ANKFN1; ASTN2; AXL; BOC;