Primary polydipsia Alcoholism may cause physiological thirst since ethanol inhibits vasopressin, the hormone primarily responsible for water retention in osmoregulation. The following conditions should also be excluded: DI, cerebral salt wasting, pseudohyponatraemia caused by hyperlipidemia or hyperparaproteinemia, SIADH, mineralcorticoid deficiency, salt-wasting nephropathy, nephrotic syndrome, chronic heart failure and cirrhosis. Tobacco smoking is an often overlooked factor linked to hyponatremia, due to the ADH-releasing effect of nicotine, although this is usually limited to heavy smokers. One study suggested that around 70% of patients with self-induced polydipsia were tobacco smokers. Diagnostic tests for primary polydipsia usually involves the fluid deprivation test to exclude ADH
A Weekend in the City track, "Song for Clay (Disappear Here)", was inspired by ""Less Than Zero"", a novel by Bret Easton Ellis which depicts excessive hedonism and its effects on individuals. The song title references the protagonist Clay and a billboard in the book which displays the phrase "Disappear Here", while the action is relocated to Les Trois Garçons restaurant in Shoreditch, East London. "Waiting for the 7.18" provides an escapist counterpoint by mentioning a trip to Brighton following disillusionment with working life in the capital. The fifth song on "A Weekend in the City", "Uniform", references London again and criticises the youth subculture