AC Omonia was then accepted by the Cyprus Football Association to participate in the Cypriot First Division After joining the Cypriot First Division in 1953, Omonia only placed seventh out of nine teams in the 1953–54 season, barely avoiding relegation. During that decade, the club's best placing came during the 1956–57 season when the club finished in the third position. The team would make its closest push for the title during the 1959–60 season after finishing second, one point behind Anorthosis Famagusta. The following year, after seven seasons in the First Division, the club would win its first title in 1960–61 season.
Anorthosis Famagusta FC in European football last game they lost 1–0 away to Panathinaikos. Inter (who had already qualified for the next stage) lost 2–1 to Bremen, meaning that Anorthosis finished fourth – missing out on a consolation UEFA Cup place. In the week prior to the game against Panathinaikos the club was disrupted when the Directors complained to the police that the President was embezzling funds. He was remanded in custody and forced to resign, eventually being released by the police without charges. Uefa Cup 1991–92: The return in European salons after 8 years of absence. Anorthosis was invited to address the 1986 European champion,