Gamgee Tissue possibly led to the character name (Sam Gamgee) in J. R. R. Tolkien's "The Lord of the Rings". The connection is not certain: in Appendix F to "The Lord of the Rings", Tolkien mentions, but at the same time denies, the reading of "Gamgee" as a pun relating to the name of Sam's wife, Rosie "Cotton". He further elaborates the 'real' Westron names of which 'Gamgee' and 'Cotton' are translations. However, in the same section Tolkien also addresses "hobbit" (which was certainly created first and translated afterward, as described in Tolkien's own comment on the initial writing of "The Hobbit")
The Lord of the Rings: Aragorn's Quest Shire to live in Rivendell, and upon the advice of Gandalf had (very reluctantly) given the Ring to his nephew, Frodo Baggins. With the information given him by Gollum, Sauron, still unable to take physical form, thus sent the Nazgûl to the Shire to retrieve the One Ring. Frodo, and his friends, Samwise Gamgee, Peregrin "Pippin" Took and Meriadoc "Merry" Brandybuck managed to escape the Shire and head towards Bree. The game is set fifteen years after the War of the Ring. Sam (voiced by Sean Astin) is now Mayor of the Shire, and is preparing a party for Aragorn,