Nicklas Bäckström Nicklas Bäckström Nicklas Bäckström (; born 23 November 1987) is a Swedish professional ice hockey centre and an alternate captain for the Washington Capitals of the National Hockey League (NHL). Bäckström was selected fourth overall by the Capitals at the 2006 NHL Entry Draft, and has since gone on to become Washington's all-time franchise leader in assists. Bäckström won his first Stanley Cup with the Capitals in 2018. Bäckström was born and raised in Valbo, Sweden. His father, Anders, was a professional ice hockey player, who won a championship with the Brynäs and retired shortly after Bäckström was born. His
Transporter associated with antigen processing Transporter associated with antigen processing Transporter associated with antigen processing (TAP) protein complex belongs to the ATP-binding-cassette transporter family. It delivers cytosolic peptides into the endoplasmic reticulum (ER), where they bind to nascent MHC class I molecules. The TAP structure is formed of two proteins: TAP-1 and TAP-2, which have one hydrophobic region and one ATP-binding region each. They assemble into a heterodimer, which results in a four-domain transporter. The TAP transporter is found in the ER lumen associated with the "peptide-loading complex" (PLC). This complex of β2 microglobulin, calreticulin, ERp57, TAP, tapasin, and MHC class I acts to keep