Spinone Italiano square build (the length of the body is approximately equal to the height at the withers). It is a strong-boned, solidly built dog with a well-muscled body and limbs that are suited to almost any kind of terrain. A brown and white Spinone can sometimes be confused with a German Wirehaired Pointer by someone unfamiliar with the breeds. However, the long head and pronounced occipital are unique to the breed. He has an expression that shows intelligence and understanding and is often described as having human-like eyes. The tail of the working Spinone is customarily docked at half its length
Fibronectin type III domain Fibronectin type III domain The Fibronectin type III domain is an evolutionary conserved protein domain that is widely found in animal proteins. The fibronectin protein in which this domain was first identified contains 16 copies of this domain. The domain is about 100 amino acids long and possesses a beta sandwich structure. Of the three fibronectin-type domains, type III is the only one without disulfide bonding present. Fibronectin domains are found in a wide variety of extracellular proteins. They are widely distributed in animal species, but also found sporadically in yeast, plant and bacterial proteins. ABI3BP; ANKFN1; ASTN2; AXL; BOC;