Primary polydipsia Alcoholism may cause physiological thirst since ethanol inhibits vasopressin, the hormone primarily responsible for water retention in osmoregulation. The following conditions should also be excluded: DI, cerebral salt wasting, pseudohyponatraemia caused by hyperlipidemia or hyperparaproteinemia, SIADH, mineralcorticoid deficiency, salt-wasting nephropathy, nephrotic syndrome, chronic heart failure and cirrhosis. Tobacco smoking is an often overlooked factor linked to hyponatremia, due to the ADH-releasing effect of nicotine, although this is usually limited to heavy smokers. One study suggested that around 70% of patients with self-induced polydipsia were tobacco smokers. Diagnostic tests for primary polydipsia usually involves the fluid deprivation test to exclude ADH
What is a Masterpiece? What is a Masterpiece? What is a Masterpiece? is a 1979 non-fiction book by British historian Kenneth Clark. It is a transcribed version of the Walter Neurath memorial lectures given by Clark. The work, initially released on 1 January 1979, received a Thames & Hudson republication on 1 May 1992. Kenneth Clark had already achieved fame with a series of popular books while also serving as, from 1969 on, the writer, producer and presenter of the BBC programme, "Civilisation", a pioneering television documentary series. The prestigious series earned a Peabody Award as well as general commercial success. In the work,