Development of the human body used to approximately judge a child's age based on physical development. Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a girl, the testes in a boy. In response to the signals, the gonads produce hormones that stimulate libido and the growth, function, and transformation of the brain, bones, muscle, blood, skin, hair, breasts, and sex organs. Physical growth—height and weight—accelerates in the first half of puberty and is completed when an adult
Effect of spaceflight on the human body adult. In space, however, there is an increase in osteoclast activity due to microgravity. This is a problem, because osteoclasts break down the bones into minerals that are reabsorbed by the body. Osteoblasts are not consecutively active with the osteoclasts, causing the bone to be constantly diminished with no recovery. This increase in osteoclasts activity has been seen particularly in the pelvic region, because this is the region which carries the biggest load with gravity present. A study demonstrated that in healthy mice, osteoclasts appearance increased by 197%, accompanied by a down-regulation of osteoblasts and growth factors that are known