Master and Commander: The Far Side of the World around Cape Horn is taken from the novel "Desolation Island", although the "Acheron" replaced the Dutch 74-gun warship "Waakzaamheid", the "Surprise" replaced the "Leopard", and in the book it is Aubrey who is being pursued around the Cape of Good Hope. The episode in which Aubrey deceives the enemy by means of a raft bearing lanterns is taken from "Master and Commander", and the episode in which Maturin directs the surgery on himself, while gritting his teeth in pain, to remove a bullet is taken from "HMS Surprise". Other incidents in the film come from other books in O'Brian's series.
The Far Side of the World film, Christopher Hitchens commented on the action scenes from this novel that were depicted in the film. He finds "the summa of O'Brian's genius was the invention of Dr. Stephen Maturin. He is the ship's gifted surgeon, but he is also a scientist, an espionage agent for the Admiralty, a man of part Irish and part Catalan birth—and a revolutionary. He joins the British side, having earlier fought against it, because of his hatred for Bonaparte's betrayal of the principles of 1789—principles that are perfectly obscure to bluff Capt. Jack Aubrey. Any cinematic adaptation of O'Brian must stand or fall