AC Omonia was then accepted by the Cyprus Football Association to participate in the Cypriot First Division After joining the Cypriot First Division in 1953, Omonia only placed seventh out of nine teams in the 1953–54 season, barely avoiding relegation. During that decade, the club's best placing came during the 1956–57 season when the club finished in the third position. The team would make its closest push for the title during the 1959–60 season after finishing second, one point behind Anorthosis Famagusta. The following year, after seven seasons in the First Division, the club would win its first title in 1960–61 season.
2013–14 Anorthosis Famagusta F.C. season twice (94', 97'). In 85' Omonia just brought the game to equalize with Łukasz Gikiewicz. Anorthosis-Apollon: (3–1) On 15 September, With two heads of Roberto Colautti that reached the 4 goals in 2 games, Anorthosis made 2 wins 2 games in the league, and defeated Apollon 3−1. Roberto Colautti opened the score at 13' and Gonzalo García made the 2−0 with penalty at 30', Apollo lowered the score with Christos Karipidis at 58' and Roberto Colautti gave the victory to Anorthosis with header at 76' Alki-Anorthosis: (0−4) On 22 September, Without struggle especially Anorthosis arrived in broad 4−0 win at