Primary polydipsia the response of the kidneys to vasopressin, thus reducing the kidney's ability to concentrate the urine. This means that psychogenic polydipsia may lead to test results (e.g. in a water restriction test) consistent with diabetes insipidus or SIADH, leading to misdiagnosis. Dry mouth is often a side effect of medications used in the treatment of some mental disorders, rather than being caused by the underlying condition. Such medications include antipsychotics, antidepressants, anticonvulsants, alpha agonists and anticholinergics. It should also be ensured that the thirst isn't caused by diuretic use (particularly thiazide diuretics), MDMA use, excessive solute intake or chronic alcoholism.
Primary polydipsia Primary polydipsia Primary polydipsia is a form of polydipsia characterised by excessive fluid intake in the absence of physiological stimuli to drink. This includes psychogenic polydipsia (PPD – not to be confused with postpartum depression), which is caused by psychiatric disorders, often schizophrenia, and often accompanied by the sensation of dry mouth. Some forms of primary polydipsia are explicitly non-psychogenic. Primary polydipsia is a diagnosis of exclusion. In diagnosis, primary polydipsia is usually categorised as: The terms primary polydipsia and psychogenic polydipsia are sometimes incorrectly used interchangeably – to be considered psychogenic, the patient needs to have some other psychiatric