Nicklas Lidström Nicklas Lidström Erik Nicklas Lidström (; born 28 April 1970) is a Swedish former professional ice hockey defenceman who played 20 seasons in the National Hockey League (NHL) for the Detroit Red Wings, which he captained for the final six seasons of his career. He is widely regarded to be one of the greatest defensemen in NHL history. Over his 20 NHL seasons, Lidström won four Stanley Cup championships, seven James Norris Memorial Trophies (awarded to the NHL's top defenceman), one Conn Smythe Trophy as the playoff MVP, and was voted into 12 NHL All-Star Games. The Red Wings never
Transporter associated with antigen processing Transporter associated with antigen processing Transporter associated with antigen processing (TAP) protein complex belongs to the ATP-binding-cassette transporter family. It delivers cytosolic peptides into the endoplasmic reticulum (ER), where they bind to nascent MHC class I molecules. The TAP structure is formed of two proteins: TAP-1 and TAP-2, which have one hydrophobic region and one ATP-binding region each. They assemble into a heterodimer, which results in a four-domain transporter. The TAP transporter is found in the ER lumen associated with the "peptide-loading complex" (PLC). This complex of β2 microglobulin, calreticulin, ERp57, TAP, tapasin, and MHC class I acts to keep