Sclera Sclera The sclera, also known as the white of the eye, is the opaque, fibrous, protective, outer layer of the human eye containing mainly collagen and some elastic fiber. In humans, the whole sclera is white, contrasting with the coloured iris, but in other mammals the visible part of the sclera matches the colour of the iris, so the white part does not normally show. In the development of the embryo, the sclera is derived from the neural crest. In children, it is thinner and shows some of the underlying pigment, appearing slightly blue. In the elderly, fatty deposits on
Development of the human cerebral cortex during neurogenesis at mouse E10.5 to E12.5. Of the six layers found within the cortex, "layer 1 is the most superficial layer of the cortex...composed of Cajal-Retzius neurons and pyramidal cortex cells." This layer is unique in the aspect that these cells migrate to the outer edge of the cortex opposed to the migration experienced by the other 5 layers. Layer one is also characterized by expression of reelin, transcription factor T-box brain 1, and cortical migratory neuronal marker. The second and third layers, or the External Granular layer and External Pyramidal layer respectively, are formed around mouse E13.5 to