History of aspirin History of aspirin The history of aspirin (IUPAC name acetylsalicylic acid ) begins with its synthesis and manufacture in 1899. Before that, salicylic acid had been used medicinally since antiquity. Medicines made from willow and other salicylate-rich plants appear in clay tablets from ancient Sumer as well as the Ebers Papyrus from ancient Egypt. Hippocrates referred to their use of salicylic tea to reduce fevers around 400 BC, and were part of the pharmacopoeia of Western medicine in classical antiquity and the Middle Ages. Willow bark extract became recognized for its specific effects on fever, pain and inflammation in the
Bark (botany) of the periderm. The outer bark on trees which lies external to the last formed periderm is also called the rhytidome. Products derived from bark include: bark shingle siding and wall coverings, spices and other flavorings, tanbark for tannin, resin, latex, medicines, poisons, various hallucinogenic chemicals and cork. Bark has been used to make cloth, canoes, and ropes and used as a surface for paintings and map making. A number of plants are also grown for their attractive or interesting bark colorations and surface textures or their bark is used as landscape mulch. What is commonly called bark includes a