Isabelline (colour) form of leucism caused by a uniform reduction in the production and expression of melanin resulting in areas of plumage on the back of the bird, normally black, being strongly faded, or isabelline, in appearance. Isabellinism has been reported in several species of penguin. Isabelline and isabella are terms applied in Europe to very pale palomino or cremello horses, animals with a coat colour that is variously described as cream, pale gold or almost white; this is the primary usage of the French ("isabelle") and German ("Isabella") versions of the word. In horses, this colour is created by the action
Design–Expert Design–Expert Design–Expert is a statistical software package from Stat-Ease Inc. that is specifically dedicated to performing design of experiments (DOE). Design–Expert offers comparative tests, screening, characterization, optimization, robust parameter design, mixture designs and combined designs. Design–Expert provides test matrices for screening up to 50 factors. Statistical significance of these factors is established with analysis of variance (ANOVA). Graphical tools help identify the impact of each factor on the desired outcomes and reveal abnormalities in the data. Stat-Ease released its first version of Design–Expert in 1988. In 1996 the firm released version 5 which was the first version of the software