Gene therapy of the human retina reduction may lead to the development of AMD. In animal model, an AAV with human PEDF cDNA under the control of the CMV promoter prevented choroidal and retinal NV ( 24). The finding suggests that the AAV-mediated expression of angiostatic factors can be implemented to treat NV. This approach could be useful as an alternative to frequent injections of recombinant protein into the eye. In addition, PEDF and sFlt-1 may be able to diffuse through sclera tissue, allowing for the potential to be relatively independent of the intraocular site of administration. Gene therapy of the human retina Retinal gene therapy
Errors of the Human Body Ruzin of Screen Invasion wrote, ""Errors of the Human Body" is elevated by a sublime turn by star Michael Eklund... His agony, particularly in the third act, is brilliantly painful. Despite the screenplay skimming over his character’s supposed scientific prowess, to the film’s moderate detriment, Eklund’s powerful performance is nonetheless tragic and captivating." Michael Treveloni of Film School Rejects noted, "The film is a not just a science-fiction horror story: it is a commentary on the importance of dialog, showcasing the need for communication in its many forms. With Geoff, "Errors" presents the perfect, damaged subject.". At the Fantastic Fest