Glutamate flavoring the neck, gradually radiating to both arms and the back, general weakness and palpitations... The syndrome is often abbreviated as CRS and also became known under the names Chinese food syndrome and monosodium glutamate symptom complex. Symptoms attributed to the Chinese restaurant syndrome have been determined to be false. Although many people believe that monosodium glutamate (MSG) is the cause of these symptoms, an association has never been demonstrated under rigorously controlled conditions, even in studies with people who were convinced that they were sensitive to the compound. Techniques used to adequately control for experimental bias include a placebo-controlled double-blinded
Scombroid food poisoning partly elevated. Antihistamines such as diphenhydramine and ranitidine together with intravenous fluids may help with mild to moderate symptoms. Epinephrine and methylprednisolone may be used for severe symptoms. The syndrome is named after the Scombridae family of fish, which includes mackerels, tunas and bonitos, because early descriptions of the illness noted an association with those species, although nonscombroid fish such as mahi-mahi and amberjack may also cause the condition. Isolated reports of scombroid food poisoning in humans caused by histamine present in the tissues of stale or rotten scombroid fish, usually tuna, have occurred over the years. In September 2016,