Ittar Abi Ali al Sina, regarded as a noble Doctor who ever lived. He was among the first people to come with the technique of distillation of roses and other plant fragrances. Liquid perfumes used to be a mixture of oil and crushed herbs until his discovery where he first experimented with roses. The traditional Attar-makers also used petals which were ground into a strong blend. His popularity spread over other continents after he created Rosewater which was more delicate than the previous versions. He formulated at least 62 cardiac medicines out of which 40 were made from Attar. They include
Bergamot essential oil directly to the skin via a patch test, followed by exposure to ultraviolet light, a concentration-dependent phototoxic effect is observed. However, if the oil is twice rectified (and therefore bergapten-free), no phototoxic response is observed. The International Fragrance Association (IFRA) restricts the use of bergamot essential oil due to its phototoxic effects. Specifically, IFRA recommends that leave-on skin products be limited to 0.4% bergamot oil, which is more restrictive than any other citrus-based essential oil. Although generally recognized as safe for human consumption, bergamot essential oil contains a significant amount of bergamottin, one of two furanocoumarins believed to be responsible