History of aspirin other studies from the 1960s to the 1980s established aspirin's efficacy as an anti-clotting agent that reduces the risk of clotting diseases. Aspirin sales revived considerably in the last decades of the twentieth century, and remain strong in the twenty-first with widespread use as a preventive treatment for heart attacks and strokes. Medicines derived from willow trees and other salicylate-rich plants have been part of pharmacopoeias at least dating back to ancient Sumer. The Ebers Papyrus, an Egyptian medical text from ca. 1543 BCE, mentions use of willow and myrtle (another salicylate-rich plant) to treat fever and pain. Willow bark
Bark mill Bark mill Bark mills, also known as Catskill’s mills, were water, steam, horse, ox or wind-powered edge mills used to process the bark, roots, and branches of various tree species into a fine powder known as tanbark, used for tanning leather. This powdering allowed the tannin to be extracted more efficiently from its woody source material. A barker would strip the bark from trees so that it might be ground in such mills, and the dried bark was often stored in bark houses. Various machinery was used to chop, grind, riddle and pound the bark. These included Farcot’s bark-cutting machine,