Caroline of Ansbach his father's political beliefs, and complained of his lack of influence in government. The Regency Act 1728 made Caroline rather than Frederick regent when her husband was in Hanover for five months from May 1729. During her regency, a diplomatic incident with Portugal (where a British ship had been seized on the Tagus) was defused, and the negotiation of the Treaty of Seville between Britain and Spain was concluded. From May 1732, she was regent for four months while George II was again away in Hanover. An investigation into the penal system uncovered widespread abuses, including cruel treatment and conspiracy
Caroline of Ansbach physics discussion of the 18th century. She helped to popularise the practice of variolation (an early type of immunisation), which had been witnessed by Lady Mary Wortley Montagu and Charles Maitland in Constantinople. At the direction of Caroline, six condemned prisoners were offered the chance to undergo variolation instead of execution: they all survived, as did six orphan children given the same treatment as a further test. Convinced of its medical value, Caroline had her children Amelia, Caroline and Frederick inoculated against smallpox in the same manner. In praising her support for smallpox inoculation, Voltaire wrote of her, "I must