Gene therapy of the human retina reduction may lead to the development of AMD. In animal model, an AAV with human PEDF cDNA under the control of the CMV promoter prevented choroidal and retinal NV ( 24). The finding suggests that the AAV-mediated expression of angiostatic factors can be implemented to treat NV. This approach could be useful as an alternative to frequent injections of recombinant protein into the eye. In addition, PEDF and sFlt-1 may be able to diffuse through sclera tissue, allowing for the potential to be relatively independent of the intraocular site of administration. Gene therapy of the human retina Retinal gene therapy
Heart's Desire (The Outer Limits) Heart's Desire (The Outer Limits) "Heart's Desire" is an episode of "The Outer Limits" television show (new series). It was first aired on 28 February 1997, during the third season. It is set in the town of Heart's Desire in the Oregon Territory in 1872. In the episode, a visitor from another world takes over the body of a human preacher. He gives four outlaws a special energy power, which they can use to destroy anything they wish as long as they "want it more than anything else". The first outlaws to be given these powers are two friends, Frank