Gene therapy of the human retina reduction may lead to the development of AMD. In animal model, an AAV with human PEDF cDNA under the control of the CMV promoter prevented choroidal and retinal NV ( 24). The finding suggests that the AAV-mediated expression of angiostatic factors can be implemented to treat NV. This approach could be useful as an alternative to frequent injections of recombinant protein into the eye. In addition, PEDF and sFlt-1 may be able to diffuse through sclera tissue, allowing for the potential to be relatively independent of the intraocular site of administration. Gene therapy of the human retina Retinal gene therapy
Catholic theology of the body dominating all subordinate material instincts, becomes similar to God. This similarity must be goal of all human undertaking. Gregory of Nazianzus (330-390) contemplated on the origin of the human body. Man was created by God with body and soul, a visible and invisible part, like the angels. He was created to praise God like they did. The body was given to man, so he may suffer and eventually die, and thus not consider himself to be God. The material essence of the body separates us from God, like a cloud, or, as Gregory stated, like the cloud between the Egyptians