Aspirin to other NSAIDs but also suppresses the normal functioning of platelets. One common adverse effect is an upset stomach. More significant side effects include stomach ulcers, stomach bleeding, and worsening asthma. Bleeding risk is greater among those who are older, drink alcohol, take other NSAIDs, or are on other blood thinners. Aspirin is not recommended in the last part of pregnancy. It is not generally recommended in children with infections because of the risk of Reye syndrome. High doses may result in ringing in the ears. A precursor to aspirin found in leaves from the willow tree has been used
Mechanism of action of aspirin form blood clots. Low-dose, long-term aspirin use irreversibly blocks the formation of thromboxane A in platelets, producing an inhibitory effect on platelet aggregation. This antiplatelet property makes aspirin useful for reducing the incidence of heart attacks; heart attacks are primarily caused by blood clots, and their reduction with the introduction of small amounts of aspirin has been seen to be an effective medical intervention. A dose of 40 mg of aspirin a day is able to inhibit a large proportion of maximum thromboxane A release provoked acutely, with the prostaglandin I2 synthesis being little affected; however, higher doses of aspirin