History of aspirin other studies from the 1960s to the 1980s established aspirin's efficacy as an anti-clotting agent that reduces the risk of clotting diseases. Aspirin sales revived considerably in the last decades of the twentieth century, and remain strong in the twenty-first with widespread use as a preventive treatment for heart attacks and strokes. Medicines derived from willow trees and other salicylate-rich plants have been part of pharmacopoeias at least dating back to ancient Sumer. The Ebers Papyrus, an Egyptian medical text from ca. 1543 BCE, mentions use of willow and myrtle (another salicylate-rich plant) to treat fever and pain. Willow bark
Mother of the Forest inserted rods into the holes to support the weight of the scaffolding and the workers while the bark was sawed off. Over 90 days, 60 tons of bark was removed in high and wide sections up to the height of . The bark was thick at the base, and on average . Gale sent samples of the tree to foresters in the east where it was discovered to be 2,520 years old. The removed sections of the bark were shipped by sea around Cape Horn to New York, where they were reassembled in 1855 in the shape of the tree