Gene therapy of the human retina reduction may lead to the development of AMD. In animal model, an AAV with human PEDF cDNA under the control of the CMV promoter prevented choroidal and retinal NV ( 24). The finding suggests that the AAV-mediated expression of angiostatic factors can be implemented to treat NV. This approach could be useful as an alternative to frequent injections of recombinant protein into the eye. In addition, PEDF and sFlt-1 may be able to diffuse through sclera tissue, allowing for the potential to be relatively independent of the intraocular site of administration. Gene therapy of the human retina Retinal gene therapy
The Human Factor (1963 The Outer Limits) mind probe machine - with help from Ingrid - to himself and to Brothers. At the final moment of the process, just before Brothers dies, Hamilton's mind is successfully returned to his body. Afterwards, both Hamilton and Ingrid try to make sense of the ordeal, while wondering how to explain the unbelievable circumstances surrounding Brothers' death, with Hamilton suggesting that they simply tell the truth - Maj. Brothers shot himself. The Human Factor (1963 The Outer Limits) "The Human Factor" is an episode of the original "The Outer Limits" television show. It first aired on 11 November 1963, during the