Tree from the cinchona tree ("Cinchona") and was for a long time the remedy of choice for the treatment of malaria. Aspirin was synthesised to replace the sodium salicylate derived from the bark of willow trees ("Salix") which had unpleasant side effects. The anti-cancer drug Paclitaxel is derived from taxol, a substance found in the bark of the Pacific yew ("Taxus brevifolia"). Other tree based drugs come from the paw-paw ("Carica papaya"), the cassia ("Cassia spp."), the cocoa tree ("Theobroma cacao"), the tree of life ("Camptotheca acuminata") and the downy birch ("Betula pubescens"). The papery bark of the white birch tree
Mother of the Forest inserted rods into the holes to support the weight of the scaffolding and the workers while the bark was sawed off. Over 90 days, 60 tons of bark was removed in high and wide sections up to the height of . The bark was thick at the base, and on average . Gale sent samples of the tree to foresters in the east where it was discovered to be 2,520 years old. The removed sections of the bark were shipped by sea around Cape Horn to New York, where they were reassembled in 1855 in the shape of the tree