Gene therapy of the human retina reduction may lead to the development of AMD. In animal model, an AAV with human PEDF cDNA under the control of the CMV promoter prevented choroidal and retinal NV ( 24). The finding suggests that the AAV-mediated expression of angiostatic factors can be implemented to treat NV. This approach could be useful as an alternative to frequent injections of recombinant protein into the eye. In addition, PEDF and sFlt-1 may be able to diffuse through sclera tissue, allowing for the potential to be relatively independent of the intraocular site of administration. Gene therapy of the human retina Retinal gene therapy
History of beliefs about the human body is important to understanding histories of coercion and control, sex and gender, and other important but culturally varied aspects of human experience. Another prominent voice in the field at the same time was Caroline Walker Bynum, whose 1988 "Holy Feast and Holy Fast" became a landmark study. Both Bynum and Porter noted that during the 1980s Western history of the body research drew on post-structuralist thought, such as Michel Foucault's ideas of biopolitics and biopower, which emphasised that state power is not abstract, but exercised through and over human bodies. But both expressed a concern that research was focusing too