Tuberculosis in human culture the disease, which allegedly helped them to see life more clearly and to act decisively. In 1680 John Bunyan referred to it as "the captain of all these men of death". Several major operas have exploited the theme of heroines dying tragically of tuberculosis, including Mimì in Puccini's opera "La bohème". Giuseppe Verdi's "La Traviata" features the consumptive Violetta Valéry, based on Marguerite Gautier in Alexandre Dumas, "fils"'s 1848 novel "La Dame aux Camélias". In Jacques Offenbach's opera "The Tales of Hoffmann", Antonia has tuberculosis and is under the control of a Svengali-like quack doctor who forces her to sing
Giuseppe Verdi Milan. The La Scala impresario, Bartolomeo Merelli, agreed to put on "Oberto" (as the reworked opera was now called, with a libretto rewritten by Temistocle Solera) in November 1839. It achieved a respectable 13 additional performances, following which Merelli offered Verdi a contract for three more works. While Verdi was working on his second opera "Un giorno di regno", Margherita died of encephalitis at the age of 26. Verdi adored his wife and children and was devastated by their deaths. "Un giorno", a comedy, was premiered only a few months later. It was a flop and only given the one