History of aspirin tree in 1758 and noticed an astringency reminiscent of the standard—and expensive—ague cure of Peruvian bark. He collected, dried, and powdered a substantial amount of willow bark, and over the next five years tested it on a number of people sick with fever and agues. In his letter, Stone reported consistent success, describing willow extract's effects as identical to Peruvian bark, though a little less potent. (In fact, the active ingredient of Peruvian bark was quinine, which attacked the infectious cause of malaria, while the active ingredient of willow extract, salicin, relieved the symptoms of malaria but could not cure
Bark at the Moon feature drummer Tommy Aldridge, who was a fixture of Osbourne's live band for several years in the early to mid-1980s. He was fired after the recording of the album and briefly replaced by Carmine Appice, but returned mid-tour after Appice was removed by the Osbournes. When asked why Aldridge was brought back, Osbourne told "Hit Parader" magazine in early 1984 "For health reasons. He (Appice) was making me sick." Nonetheless, Appice did appear in the popular music video for the "Bark at the Moon" single. "Bark at the Moon" was re-issued again in 2002, although this version was actually a