Glutamate flavoring the neck, gradually radiating to both arms and the back, general weakness and palpitations... The syndrome is often abbreviated as CRS and also became known under the names Chinese food syndrome and monosodium glutamate symptom complex. Symptoms attributed to the Chinese restaurant syndrome have been determined to be false. Although many people believe that monosodium glutamate (MSG) is the cause of these symptoms, an association has never been demonstrated under rigorously controlled conditions, even in studies with people who were convinced that they were sensitive to the compound. Techniques used to adequately control for experimental bias include a placebo-controlled double-blinded
Food addiction asking a series of questions called the YFAS questionnaire, a diagnostic criteria of substance dependence. Sugary and high-fat food have both been shown to increase the expression of ΔFosB, an addiction biomarker, in the D1-type medium spiny neurons of the nucleus accumbens; however, there is very little research on the synaptic plasticity from compulsive food consumption, a phenomenon which is known to be caused by ΔFosB overexpression. "Food addiction" refers to compulsive overeaters who engage in frequent episodes of uncontrolled eating (binge eating). The term "binge eating" means eating an unhealthy amount of food while feeling that one's sense of