Tuberculosis in human culture the disease, which allegedly helped them to see life more clearly and to act decisively. In 1680 John Bunyan referred to it as "the captain of all these men of death". Several major operas have exploited the theme of heroines dying tragically of tuberculosis, including Mimì in Puccini's opera "La bohème". Giuseppe Verdi's "La Traviata" features the consumptive Violetta Valéry, based on Marguerite Gautier in Alexandre Dumas, "fils"'s 1848 novel "La Dame aux Camélias". In Jacques Offenbach's opera "The Tales of Hoffmann", Antonia has tuberculosis and is under the control of a Svengali-like quack doctor who forces her to sing
Giuseppe Verdi with Boito, produced in 1881, and a revision of "Don Carlos". Even when "Otello" was virtually completed, Verdi teased "Shall I finish it? Shall I have it performed? Hard to tell, even for me." As news leaked out, Verdi was pressed by opera houses across Europe with enquiries; eventually the opera was triumphantly premiered at La Scala in February 1887. Following the success of "Otello" Verdi commented, "After having relentlessly massacred so many heroes and heroines, I have at last the right to laugh a little." He had considered a variety of comic subjects but had found none of them