History of aspirin other studies from the 1960s to the 1980s established aspirin's efficacy as an anti-clotting agent that reduces the risk of clotting diseases. Aspirin sales revived considerably in the last decades of the twentieth century, and remain strong in the twenty-first with widespread use as a preventive treatment for heart attacks and strokes. Medicines derived from willow trees and other salicylate-rich plants have been part of pharmacopoeias at least dating back to ancient Sumer. The Ebers Papyrus, an Egyptian medical text from ca. 1543 BCE, mentions use of willow and myrtle (another salicylate-rich plant) to treat fever and pain. Willow bark
History of aspirin the term "aspirin". The Australian market was taken over by "Aspro", after the makers of Nicholas-Aspirin lost a short-lived exclusive right to the "aspirin" name there. In the United States, Bayer was still under German control—though the war disrupted the links between the American Bayer plant and the German Bayer headquarters—but phenol shortage threatened to reduce aspirin production to a trickle, and imports across the Atlantic Ocean were blocked by the Royal Navy. To secure phenol for aspirin production, and at the same time indirectly aid the German war effort, German agents in the United States orchestrated what became known