Atelectasis Leakage of air into the pleural cavity (pneumothorax) also leads to compression atelectasis. It occurs when either local or generalized fibrotic changes in the lung or pleura hamper expansion and increase elastic recoil during expiration. Causes include granulomatous disease, necrotising pneumonia and radiation fibrosis. Chronic atelectasis may take one of two forms—middle lobe syndrome or rounded atelectasis. In right middle lobe syndrome, the middle lobe of the right lung contracts, usually because of pressure on the bronchus from enlarged lymph glands and occasionally a tumor. The blocked, contracted lung may develop pneumonia that fails to resolve completely and leads to
Body plan of homeobox genes, which function as switches responsible for laying down the basic body plan in animals. The homeobox genes are remarkably conserved between species as diverse as the fruit fly and humans, the basic segmented pattern of the worm or fruit fly being the origin of the segmented spine in humans. The field of animal evolutionary developmental biology ('Evo Devo'), which studies the genetics of morphology in detail, is rapidly expanding with many of the developmental genetic cascades, particularly in the fruit fly "Drosophila", catalogued in considerable detail. Body plan A body plan, Bauplan (German plural Baupläne), or ground