Decline of the Byzantine Empire of Constantinople in 1453. The process by which the empire waned, and from when its decline can be traced, is a matter of scholarly debate. In some cases, the entire history of the Byzantine Empire has been portrayed as a protracted period of decline of the Roman Empire. This holds especially for Enlightenment era writers such as Edward Gibbon, author of "The History of the Decline and Fall of the Roman Empire", published in six volumes between 1776 and 1789, whose view was coloured by pro-western or anti-clerical biases, and tended to see the whole ten-century empire as merely a
Historiography of the fall of the Western Roman Empire to the fall of the West Roman Empire (395-476), in his book "The Fall of the West: The Slow Death of the Roman Superpower" (2009). William H. McNeill, a world historian, noted in chapter three of his book "Plagues and Peoples" (1976) that the Roman Empire suffered the severe and protracted Antonine Plague starting around 165 AD. For about twenty years, waves of one or more diseases, possibly the first epidemics of smallpox and measles, swept through the Empire, ultimately killing about half the population. Similar epidemics, such as the Plague of Cyprian, also occurred in the 3rd century. McNeill