Isabelline (colour) form of leucism caused by a uniform reduction in the production and expression of melanin resulting in areas of plumage on the back of the bird, normally black, being strongly faded, or isabelline, in appearance. Isabellinism has been reported in several species of penguin. Isabelline and isabella are terms applied in Europe to very pale palomino or cremello horses, animals with a coat colour that is variously described as cream, pale gold or almost white; this is the primary usage of the French ("isabelle") and German ("Isabella") versions of the word. In horses, this colour is created by the action
Design–Expert the number of test runs needed. ANOVA is provided to establish statistical significance. Based on the validated predictive models, a numerical optimizer helps the user determine the ideal values for each of the factors in the experiment. Design–Expert provides 11 graphs in addition to text output to analyze the residuals. The software determines the main effects of each factor as well as the interactions between factors by varying the values of all factors in parallel. A response surface model (RSM) can be used to map out a design space using a relatively small number of experiments. RSM provides an estimate