Gene therapy of the human retina reduction may lead to the development of AMD. In animal model, an AAV with human PEDF cDNA under the control of the CMV promoter prevented choroidal and retinal NV ( 24). The finding suggests that the AAV-mediated expression of angiostatic factors can be implemented to treat NV. This approach could be useful as an alternative to frequent injections of recombinant protein into the eye. In addition, PEDF and sFlt-1 may be able to diffuse through sclera tissue, allowing for the potential to be relatively independent of the intraocular site of administration. Gene therapy of the human retina Retinal gene therapy
The Description of the Human Body He believed the heat of the heart somehow caused all movement of the body. Blood vessels he realized were pipes, he saw that veins carried digested food to the heart. (This was brought further by William Harvey. Harvey developed the idea of the circulation of the blood.) Descartes felt that an energetic part of blood went to the brain and there gave the brain a special type of air imbued with vital force that enabled the brain to experience, think and imagine. This special air then went through the nerves to the muscles enabling them to move. The Description of