Sclera Sclera The sclera, also known as the white of the eye, is the opaque, fibrous, protective, outer layer of the human eye containing mainly collagen and some elastic fiber. In humans, the whole sclera is white, contrasting with the coloured iris, but in other mammals the visible part of the sclera matches the colour of the iris, so the white part does not normally show. In the development of the embryo, the sclera is derived from the neural crest. In children, it is thinner and shows some of the underlying pigment, appearing slightly blue. In the elderly, fatty deposits on
Development of the human cerebral cortex Development of the human cerebral cortex Corticogenesis is the process in which the cortex of the brain is created during neurodevelopment. The cortex is the outer layer of the brain and is composed of up to six layers. Neurons formed in the ventricular zone migrate to their final locations in one of the six layers of the cortex The process occurs from embryonic day 10 to 17 in mice and between gestational weeks seven to 18 in humans. The preplate is the first stage in corticogenesis prior to the development of the cortical plate. The preplate is located between the