The Adventures of Sherlock Holmes of the Speckled Band" as his overall favourite. Arthur Conan Doyle began writing while studying medicine at university in the late 1870s, and had his first short story, "The Mystery of Sasassa Valley", published in September 1879. After eight years, "A Study in Scarlet", Doyle's first Sherlock Holmes story, was published by Ward Lock & Co. The novel was well received, but Doyle was paid little for it, and despite a sequel novel, "The Sign of the Four", which was published in Lipincott's Monthly Magazine, he shifted his focus to short stories. In early 1891, the first editor of "The
Sherlock Holmes in the Great Murder Mystery considered a lost film. Sherlock Holmes in the Great Murder Mystery Sherlock Holmes in the Great Murder Mystery is a 1908 American silent film directed by an unknown director. The film was released on 27 November 1908 and is an adaptation of Edgar Allan Poe's short story "The Murders in the Rue Morgue" (1841), which is considered the first detective story, though the plot was altered to include Arthur Conan Doyle's detective Sherlock Holmes instead of Poe's C. Auguste Dupin. Dr. Watson makes his film debut here, though the actors playing Holmes and Watson are unknown, as the rest of