Gene therapy of the human retina reduction may lead to the development of AMD. In animal model, an AAV with human PEDF cDNA under the control of the CMV promoter prevented choroidal and retinal NV ( 24). The finding suggests that the AAV-mediated expression of angiostatic factors can be implemented to treat NV. This approach could be useful as an alternative to frequent injections of recombinant protein into the eye. In addition, PEDF and sFlt-1 may be able to diffuse through sclera tissue, allowing for the potential to be relatively independent of the intraocular site of administration. Gene therapy of the human retina Retinal gene therapy
Colonization of the outer Solar System is subject to only 0.01 rem a day. When NASA carried out a study called "HOPE" (Revolutionary Concepts for Human Outer Planet Exploration) regarding the future exploration of the Solar System, the target chosen was Callisto. It might be possible to build a surface base that would produce fuel for further exploration of the Solar System. The Keck Observatory announced in 2006 that the binary Jupiter trojan 617 Patroclus, and possibly many other Jupiter trojans, are likely composed of water ice, with a layer of dust. This suggests that mining water and other volatiles in this region and transporting them