Gene therapy of the human retina reduction may lead to the development of AMD. In animal model, an AAV with human PEDF cDNA under the control of the CMV promoter prevented choroidal and retinal NV ( 24). The finding suggests that the AAV-mediated expression of angiostatic factors can be implemented to treat NV. This approach could be useful as an alternative to frequent injections of recombinant protein into the eye. In addition, PEDF and sFlt-1 may be able to diffuse through sclera tissue, allowing for the potential to be relatively independent of the intraocular site of administration. Gene therapy of the human retina Retinal gene therapy
The Tale of the Body Thief Talbot, Lestat jumps at the opportunity. Unfortunately, James has no intention of ever switching back, and Lestat is forced to scheme to regain his body. Lestat nearly dies after becoming human again—his new body is wracked by pneumonia, which he ignores during a tour of Washington D.C. in the middle of winter. He is saved by the care of a nun named Gretchen. He enjoys a short love affair with Gretchen before she returns to South America, where she works in a convent, and Lestat sets out in search of his body. Lestat seeks help from other vampires but is