Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize controversies been favored to receive the Prize, but a committee member was later quoted as saying that they would have been "too predictable, too popular." The 1974 prize was denied to Graham Greene, Vladimir Nabokov, and Saul Bellow in favor of a joint award for Swedish authors Eyvind Johnson and Harry Martinson—both Nobel judges and unknown outside their home country. Bellow won in 1976; neither Greene nor Nabokov took home the prize. The 1970 prize was awarded to Soviet dissident Aleksandr Solzhenitsyn, who did not attend the ceremony in Stockholm for fear that the Soviet Union would prevent his return. His