The hand of God the song "La mano de Dios" in homage to Diego Maradona, his great idol. In the first round of the 1990 World Cup between Argentina and the USSR, in the first half of the 0-0 draw, a Soviet attack could not end in a goal as Diego Maradona intercepted the shot with "the hand of God" without the referee noticing it. In the second leg of the play-off for the 2010 World Cup between Ireland and France, William Gallas's goal, which scored the 1-1 draw and qualified France for the World Cup, was made possible by another controversial move, a
God Hand contained some comic relief, the team decided to integrate a large amount of comedy into the game based on the viewers' reactions. Inaba stated that "God Hand" is "aimed at hardcore gamers," which is shown in its hard difficulty. Unlike "Viewtiful Joe" and "Ōkami", the design team had no particular goal when designing the graphical style of "God Hand" other than that they wanted it to look more realistic. Although "God Hand" appears to share many elements with manga and anime such as "Fist of the North Star" and "MD Geist", none were actually used as inspiration for the game.