Culture of South Africa originated in South Africa. The first human-to-human heart transplant was performed by cardiac surgeon Christiaan Barnard at Groote Schuur Hospital in December 1967. Max Theiler developed a vaccine against Yellow Fever, Allan McLeod Cormack pioneered x-ray Computed tomography, and Aaron Klug developed crystallographic electron microscopy techniques. These advancements were all (with the exception of that of Barnard) recognised with Nobel Prizes. Sydney Brenner won most recently, in 2002, for his pioneering work in molecular biology. Mark Shuttleworth founded an early Internet security company Thawte, that was subsequently bought out by world-leader VeriSign. South Africa has cultivated a burgeoning astronomy community.
Nobel Prize controversies was acceptable for use in humans. No prize was awarded in 1921. Carlos Chagas, who had already been nominated in 1913 and was the recipient of several international awards at the time, was among the nominees. His failure in receiving the award has generated controversy, especially in his homeland, Brazil, proved that Chagas is responsible for one of the most important achievements in the history of parasitology: Chagas alone discovered a new infectious disease, Chagas disease, its pathogen, vector, host, clinical manifestation and epidemology, first describing it in 1909. According to historian Sierra Iglesias, the Nobel Assembly retrieved for Brazilian