Culture of South Africa originated in South Africa. The first human-to-human heart transplant was performed by cardiac surgeon Christiaan Barnard at Groote Schuur Hospital in December 1967. Max Theiler developed a vaccine against Yellow Fever, Allan McLeod Cormack pioneered x-ray Computed tomography, and Aaron Klug developed crystallographic electron microscopy techniques. These advancements were all (with the exception of that of Barnard) recognised with Nobel Prizes. Sydney Brenner won most recently, in 2002, for his pioneering work in molecular biology. Mark Shuttleworth founded an early Internet security company Thawte, that was subsequently bought out by world-leader VeriSign. South Africa has cultivated a burgeoning astronomy community.
Nobel Prize controversies in his novel, "Doctor Zhivago"." Pasternak died without ever receiving the prize. He was eventually honored by the Nobel Foundation at a banquet in Stockholm on 9 December 1989, when they presented his medal to his son. The 2010 Nobel Peace Prize was awarded to Liu Xiaobo while he was serving a prison sentence for "subversion of the state", with the Chinese government not allowing him or his family members to attend the ceremony. Two laureates voluntarily declined the Nobel Prize. Jean-Paul Sartre declined the 1964 prize for Literature, stating, "A writer must refuse to allow himself to be transformed