Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize five (Swedish) Nobel Prize medals to Svenska Medalj AB. Formerly, the Nobel Prize medals were minted by Myntverket (the Swedish Mint) from 1902 to 2010. Myntverket, Sweden's oldest company, ceased operations in 2011 after 1,017 years. In 2011, the Mint of Norway, located in Kongsberg, made the medals. The Nobel Prize medals are registered trademarks of the Nobel Foundation. Each medal features an image of Alfred Nobel in left profile on the obverse. The medals for physics, chemistry, physiology or medicine, and literature have identical obverses, showing the image of Alfred Nobel and the years of his birth and death.