Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize relevant fields was greater), a greater delay in awarding Nobel Prizes for women's achievements making longevity a more important factor for women (Nobel Prizes are not awarded posthumously), and a tendency to omit women from jointly awarded Nobel Prizes. Four people have received two Nobel Prizes. Marie Curie received the Physics Prize in 1903 for her work on radioactivity and the Chemistry Prize in 1911 for the isolation of pure radium, making her the only person to be awarded a Nobel Prize in two different sciences. Linus Pauling was awarded the 1954 Chemistry Prize for his research into the chemical