Max Theiler Max Theiler Max Theiler (30 January 1899 – 11 August 1972) was a South African-American virologist and physician. He was awarded the Nobel Prize in Physiology or Medicine in 1951 for developing a vaccine against yellow fever in 1937, becoming the first African-born Nobel laureate. Born in Pretoria, Theiler was educated in South Africa through completion of his degree in medical school. He went to London for postgraduate work at St Thomas's Hospital Medical School, King's College London, and at the London School of Hygiene and Tropical Medicine, earning a 1922 diploma in tropical medicine and hygiene. That year, he
Theiler's encephalomyelitis virus study the progression of a polio-like disease in mice. Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed