International Vaccine Institute strategic demand forecasting; and Sabin – communications and advocacy. Besides leading the consortium, IVI generated evidence for decision-making such as disease burden, country vaccine introduction cases and a global investment case. From 2010 to 2016, DVI operated in Brazil, Burkina Faso, Cambodia, Colombia, Gabon, India, Kenya, Thailand, and Vietnam. From 2013-2015, with funding from Germany’s Federal Ministry of Education & Research (BMBF), IVI continued support for preclinical development of dengue vaccines by Brazil’s Butantan Institute and Vietnam’s VaBiotech. After the 2016 licensure of Sanofi Pasteur’s Dengvaxia vaccine, the DVI project came to a close and its IVI staff transitioned to
Oswaldo Cruz Foundation after Oswaldo Cruz assumed its leadership in 1902. From there on, the institute became the base for memorable sanitation campaigns in an age of outbreaks and epidemics of the bubonic plague, yellow fever, and smallpox. The Institute, however, was not confined to Rio de Janeiro and, on the contrary, collaborated in the occupation of the country’s interior through scientific expeditions, aiding in the development of the country. When Oswaldo Cruz died, in 1917, the Institute, which by then already bore his name, was nationally consolidated through important scientific achievements, such as Carlos Chagas’ description of the complete cycle of the