Instituto Butantan and production of sera. The Instituto Butantan also operate the "Hospital Vital Brazil", a specialist hospital that offers free treatment for poisonous animal stings and bites. The institute also accepts donations of serpents, arthropods and other animals captured by the public and by a network of collaborating centers and individuals. The following research laboratories are part of the Butantan Institute: Important Brazilian scientists who have worked in the Butantan Institute are: Vital Brazil, Afrânio Pompílio Gastos do Amaral, Isaias Raw, Samuel Pessoa, Willy Beçak. The Institute has strong collaborative ties with the Pasteur Institute, Paris, France, and with the Oswaldo
Oswaldo Cruz following year, Cruz was appointed director general of Public Health, a position corresponding to today's Brazilian Minister of Health. Using the Federal Serum Therapy Institute as technical-scientific base, he embarked in quick succession of important sanitation campaigns. His first challenge was a series of yellow fever endemics, which had earned Rio de Janeiro the sinister reputation of 'Foreigners' Grave'. Between 1897 and 1906, 4,000 European immigrants had died there from the disease. Cruz pursued the new technique of eradicating mosquitoes and their breeding grounds, fumigating houses, and isolation of the ill. There was opposition to the campaign by many, including