Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize Paul Samuelson and Kenneth Arrow were brothers-in-law. Frits Zernike, who was awarded the 1953 Physics Prize, is the great-uncle of 1999 Physics laureate Gerard 't Hooft. Being a symbol of scientific or literary achievement that is recognisable worldwide, the Nobel Prize is often depicted in fiction. This includes films like "The Prize" and "Nobel Son" about fictional Nobel laureates as well as fictionalised accounts of stories surrounding real prizes such as "Nobel Chor", a film based on the unsolved theft of Rabindranath Tagore's prize. Two laureates have voluntarily declined the Nobel Prize. In 1964, Jean-Paul Sartre was awarded the Literature