Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize effect winners estimated that winning the Nobel Prize correlated with one or two years of additional longevity for the recipient, compared to being merely nominated for the prize. Nobel Prize effect The Nobel Prize effect is an observation about the adverse effects of winning the Nobel Prize on laureates and their careers. These effects include reduced productivity, constraints in areas of work, and public perception of expertise in areas unrelated to the laureate's work. The term Nobel effect is also used in those contexts, as well as in the context of the winner's longevity, and influence on international law in the