Max Theiler working on yellow fever. In 1926, they disproved Hideyo Noguchi's hypothesis that yellow fever was caused by the bacterium "Leptospira icteroides." In 1928, the year after the disease was identified conclusively as a virus, they showed that the African and South American viruses are immunologically identical. (This followed Adrian Stokes' inducing yellow fever in rhesus macaques from India). In the course of this research, Theiler contracted yellow fever, but survived and developed immunity. In 1930, Theiler moved to the Rockefeller Foundation in New York, where he later became director of the Virus Laboratory. He was professor of epidemiology and public
Theiler's encephalomyelitis virus study the progression of a polio-like disease in mice. Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed