Culture of South Africa originated in South Africa. The first human-to-human heart transplant was performed by cardiac surgeon Christiaan Barnard at Groote Schuur Hospital in December 1967. Max Theiler developed a vaccine against Yellow Fever, Allan McLeod Cormack pioneered x-ray Computed tomography, and Aaron Klug developed crystallographic electron microscopy techniques. These advancements were all (with the exception of that of Barnard) recognised with Nobel Prizes. Sydney Brenner won most recently, in 2002, for his pioneering work in molecular biology. Mark Shuttleworth founded an early Internet security company Thawte, that was subsequently bought out by world-leader VeriSign. South Africa has cultivated a burgeoning astronomy community.
Nobel Prize controversies Hiroshi Amano and Shuji Nakamura for the blue light-emitting diode, did not recognize the decades of incremental work in developing the LED by other pioneers such as Oleg Losev and Nick Holonyak, and did overlook the actual inventor of the blue LED: Herbert Paul Maruska. The 2010 Nobel Prize in Physics was awarded to Andre Geim and Konstantin Novoselov of the University of Manchester "for groundbreaking experiments regarding the two-dimensional material graphene". Several problems with the factual accuracy of the supporting documents issued by the Nobel committee have been pointed out, including that they seem to wrongly attribute the discovery