Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize controversies was acceptable for use in humans. No prize was awarded in 1921. Carlos Chagas, who had already been nominated in 1913 and was the recipient of several international awards at the time, was among the nominees. His failure in receiving the award has generated controversy, especially in his homeland, Brazil, proved that Chagas is responsible for one of the most important achievements in the history of parasitology: Chagas alone discovered a new infectious disease, Chagas disease, its pathogen, vector, host, clinical manifestation and epidemology, first describing it in 1909. According to historian Sierra Iglesias, the Nobel Assembly retrieved for Brazilian