Max Theiler health at the Yale School of Medicine and the School of Public Health from 1964 to 1967. After passing the yellow fever virus through laboratory mice, Theiler found that the weakened virus conferred immunity on rhesus macaques. The stage was set for Theiler to develop a vaccine against the disease. Theiler first devised a test for the efficacy of experimental vaccines. In his test, sera from vaccinated human subjects were injected into mice to see if they protected the mice against yellow fever virus. This "mouse protection test" was used with variations as a measure of immunity until after World
Nobel Prize controversies possibility is that Nobel did not consider mathematics as a practical discipline. Both the Fields Medal and the Abel Prize have been described as the "Nobel Prize of mathematics". The most notorious controversies have been over prizes for Literature, Peace and Economics. Beyond disputes over which contributor's work was more worthy, critics most often discerned political bias and Eurocentrism in the result. The interpretation of Nobel's original words concerning the Literature prize has also undergone repeated revisions. The 2008 prize was awarded to Osamu Shimomura, Martin Chalfie and Roger Y. Tsien for their work on green fluorescent protein or GFP.