Yellow fever vaccine Foundation to improve the vaccine from the "Asibi" strain, discovered that a favorable chance mutation in the attenuated virus had produced a highly efficacious strain that was named 17D. After field trials in Brazil, over one million people were vaccinated by 1939, without severe complications. For his work on the yellow fever vaccine, Theiler received the 1951 Nobel Prize in Physiology or Medicine. Only the 17D vaccine remains in use today. The outbreak of yellow fever in Angola in January 2016 has raised concerns about whether the global supply of vaccine is adequate to meet the need during a large
Nobel Prize controversies possibility is that Nobel did not consider mathematics as a practical discipline. Both the Fields Medal and the Abel Prize have been described as the "Nobel Prize of mathematics". The most notorious controversies have been over prizes for Literature, Peace and Economics. Beyond disputes over which contributor's work was more worthy, critics most often discerned political bias and Eurocentrism in the result. The interpretation of Nobel's original words concerning the Literature prize has also undergone repeated revisions. The 2008 prize was awarded to Osamu Shimomura, Martin Chalfie and Roger Y. Tsien for their work on green fluorescent protein or GFP.