Shiitake mushroom dermatitis findings. On physical exam, one key difference between the two is that post-inflammatory hyperpigmentation changes are usually seen with bleomycin-induced flagellate dermatitis and are not typically present with shiitake mushroom induced flagellate dermatitis. The median time of onset from ingestion of shiitake mushrooms is typically 24 hours, ranging from 12 hours to 5 days. Most patients completely recover by 3 weeks, with or without treatment. Although the pathogenesis of shiitake induced flagellate dermatitis is not clear, the theory most argued for is a toxic reaction to lentinan, a polysaccharide isolated from shiitake mushrooms. However, Type I and Type IV allergic
What Is This? following week. The group decided to change their name to the Red Hot Chili Peppers, played several more shows at various L.A. clubs and musical venues, and eventually recorded a demo tape, all while Slovak and Irons were still playing with What Is This?. A few months later, What Is This received a record deal with MCA Records and the Red Hot Chili Peppers received a joint deal with EMI America and Enigma Records. Hillel Slovak and Jack Irons decided to leave the Red Hot Chili Peppers and stay with What Is This? as the latter was their primary musical