Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize controversies necessarily sympathize felt that it was wrong to (deliberately) offend Germany. Hitler's decree prevented three Germans from accepting their prizes: Gerhard Domagk (1939 Nobel Prize in Physiology or Medicine), Richard Kuhn (1938 Nobel Prize in Chemistry), and Adolf Butenandt (1939 Nobel Prize in Chemistry). The three later received their certificates and medals, but not the prize money. On 19 October 1939, about a month and a half after World War II had started, the Nobel Committee of the Karolinska Institutet met to discuss the 1939 prize in physiology or medicine. The majority favored Domagk and someone leaked the news, which