Brazil tourists in 2005. In 2005, Rio de Janeiro, Foz do Iguaçu, São Paulo, Florianópolis and Salvador were the most visited cities by international tourists for leisure trips. The most popular destinations for business trips were São Paulo, Rio de Janeiro and Porto Alegre. In 2006 Rio de Janeiro and Fortaleza were the most popular destinations for business trips. Technological research in Brazil is largely carried out in public universities and research institutes, with the majority of funding for basic research coming from various government agencies. Brazil's most esteemed technological hubs are the Oswaldo Cruz Institute, the Butantan Institute, the Air
Oswaldo Cruz following year, Cruz was appointed director general of Public Health, a position corresponding to today's Brazilian Minister of Health. Using the Federal Serum Therapy Institute as technical-scientific base, he embarked in quick succession of important sanitation campaigns. His first challenge was a series of yellow fever endemics, which had earned Rio de Janeiro the sinister reputation of 'Foreigners' Grave'. Between 1897 and 1906, 4,000 European immigrants had died there from the disease. Cruz pursued the new technique of eradicating mosquitoes and their breeding grounds, fumigating houses, and isolation of the ill. There was opposition to the campaign by many, including