Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize effect it hard for a scientist to work on small problems after winning the prize. During a speech at a seminar, Hamming described a scene at the Nobel awards ceremony as follows: The Nobel Prize effect is also described as a consequence of public perception of the Nobel laureate, magnified by the worldwide exposure the winner experiences. One example is for the Nobel laureate to be treated with reverence due to perception that the laureate has authoritative knowledge about any subject outside the field in which he or she won the prize. Nobel Laureate Klaus von Klitzing describes the effect as