Corsica and the Pope: finally, in 1450 Genoa ceded the administration of the island to its main bank, the Bank of Saint George, which brought peace. In the 16th century, the island entered into the fight between Spain and France for the supremacy in Italy. In 1553, a Franco-Ottoman fleet occupied Corsica, but the reaction of Spain and Genoa, led by Andrea Doria, reestablished the Genoese supremacy on the island, confirmed by the Peace of Cateau-Cambresis. The unlucky protagonist of this episode was Sampiero di Bastelica, who would later come to be considered a hero of the island. Their power reinstated,
Roman Catholic Diocese of Mariana in Corsica greatly compromised. In 1453 Pope Nicholas V entered into a verbal agreement with the Republic of Genoa, which specified that, although the Pope maintained the exclusive right to appoint bishops on the Island of Corsica, he would appoint only Genoese subjects who were acceptable to the Government. The Genoese government turned the island over to the administration of the Genoese Banco di S. Giorgio, under new statutes for Corsica were issued, the "Capitula Corsorum", which specified that bishops on the island had to be natives of the island. In 1464, however, the Republic of Genoa came under the domination of