Self-experimentation in medicine 18th century. There was an unsuccessful campaign to award a Nobel Prize to Reed's team. Lazear, in any event, could not be awarded the prize because it is never given posthumously. However, a Nobel Prize was awarded to a later yellow fever researcher and self-experimenter, Max Theiler who, in 1951, developed the first yellow fever vaccine and was the first to try it. Anatolii Al'bertovich Shatkin, in 1961, injected trachoma virus into the conjunctival sac of his eye and rapidly developed trachoma. He did not begin treatment of the condition for 26 days. In July 1944, physician researcher Claude Barlow
Vaccine vaccine is designed to immunize against a single antigen or single microorganism. A multivalent or polyvalent vaccine is designed to immunize against two or more strains of the same microorganism, or against two or more microorganisms. The valency of a multivalent vaccine may be denoted with a Greek or Latin prefix (e.g., "tetravalent" or "quadrivalent"). In certain cases, a monovalent vaccine may be preferable for rapidly developing a strong immune response. Also known as heterologous or "Jennerian" vaccines, these are vaccines that are pathogens of other animals that either do not cause disease or cause mild disease in the organism