Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize controversies been given a Nobel Prize because he has made known his intention to refuse the reward is ridiculous", further stating a recipient could only decline a Nobel Prize after he is announced a winner. Otto Heinrich Warburg, a German national who won the 1931 Nobel Prize in Physiology and Medicine, was rumored to have been selected for the 1944 prize but forbidden to accept it. According to the Nobel Foundation, this story is not true. Multiple primary fields of human intellectual endeavor—such as mathematics, philosophy and social studies—were not included among the Nobel Prizes, because they were not part of