Oswaldo Cruz father-in-law, a wealthy Portuguese merchant. Cruz found the seaport of Santos ravaged by an epidemic of bubonic plague that threatened to reach Rio de Janeiro and engaged himself immediately in the combat of this disease. The mayor of Rio de Janeiro authorized the construction of a plant for manufacturing the serum against the disease which had been developed at the Pasteur Institute by Alexandre Yersin and coworkers. He asked the institution for a scientist who could bring to Brazil this know-how. The Pasteur Institute responded that such a person was already available in Brazil: Dr. Oswaldo Cruz. On May 25,
South American Institute of Government in Health South American Institute of Government in Health The South American Institute of Government in Health (ISAGS) is a public intergovernamental institution of UNASUR whose main goal is to promote exchange, critical thinking, knowledge management and generate innovation in policy and governance for health, thus offering South American Health Ministries the best available practices and evidences on health management. It was created by the Heads of State and Government of UNASUR after a proposal of the South American Council of Health gathered in Cuenca, Ecuador, in April 2010. According to the institute's Executive Director José Gomes Temporão, "Isags works in alliance