Yellow fever vaccine Foundation to improve the vaccine from the "Asibi" strain, discovered that a favorable chance mutation in the attenuated virus had produced a highly efficacious strain that was named 17D. After field trials in Brazil, over one million people were vaccinated by 1939, without severe complications. For his work on the yellow fever vaccine, Theiler received the 1951 Nobel Prize in Physiology or Medicine. Only the 17D vaccine remains in use today. The outbreak of yellow fever in Angola in January 2016 has raised concerns about whether the global supply of vaccine is adequate to meet the need during a large
Nobel Prize controversies Erwin Hahn for his contribution to the principles of spin echoes. The 2000 prize went to Arvid Carlsson, Paul Greengard, and Eric R. Kandel, "for their discoveries concerning signal transduction in the nervous system". The award caused many neuroscientists to protest that Oleh Hornykiewicz, who helped pioneer the dopamine replacement treatment for Parkinson's disease, was left out, and that Hornykiewicz's research provided a foundation for the honorees' success. The Nobel Prize for Physiology or Medicine was awarded in 1998 to Robert Furchgott, Louis Ignarro and Ferid Murad "for their discoveries concerning nitric oxide as a signalling molecule in the cardiovascular