Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Nobel Prize controversies Hiroshi Amano and Shuji Nakamura for the blue light-emitting diode, did not recognize the decades of incremental work in developing the LED by other pioneers such as Oleg Losev and Nick Holonyak, and did overlook the actual inventor of the blue LED: Herbert Paul Maruska. The 2010 Nobel Prize in Physics was awarded to Andre Geim and Konstantin Novoselov of the University of Manchester "for groundbreaking experiments regarding the two-dimensional material graphene". Several problems with the factual accuracy of the supporting documents issued by the Nobel committee have been pointed out, including that they seem to wrongly attribute the discovery