William Pitt the Younger however, was comfortable with Shelburne, and thus joined his government; he was appointed Chancellor of the Exchequer. Fox, who became Pitt's lifelong political rival, then joined a coalition with Lord North, with whom he collaborated to bring about the defeat of the Shelburne administration. When Lord Shelburne resigned in 1783, King George III, who despised Fox, offered to appoint Pitt to the office of prime minister. But Pitt wisely declined, for he knew he would be incapable of securing the support of the House of Commons. The Fox–North coalition rose to power in a government nominally headed by William Cavendish-Bentinck,
William Pitt the Younger 1798 after having spent 4 million pounds (a sum roughly equal to about £224,120,000.00 in today's money) and having lost about 100,000 dead or men crippled for life over the preceding five years, due mostly to yellow fever, achieving nothing. The British historian Sir John William Fortescue wrote that Pitt and his cabinet had tried to destroy French power "in these pestilent islands ... only to discover, when it was too late, that they practically destroyed the British army". Fortescue concluded that Pitt's attempt to add St. Domingue to the British empire had killed off most of the British army,