Instituto Butantan crew of 50 firemen an hour and a half later. News reports have claimed that the facility was not prepared for a fire, not having a fire alarm or sprinkler system. Police are investigating the fire which has been described by curator Francisco Franco as "a loss for humanity". None of the live animals or people at the institute was harmed by the fire. Instituto Butantan Instituto Butantan (in modern Portuguese, Instituto Butantã, ) is a Brazilian biologic research center located in Butantã, in the western part of the city of São Paulo, Brazil. Instituto Butantan is a public institution
Oswaldo Cruz existed since 1837 but had never been put into practice. Therefore, on June 9, 1904, following a proposal by Oswaldo Cruz, the government presented a bill to the Congress requesting the reestablishment of obligatory smallpox vaccination. The extremely rigid and severe provisions of this instrument terrified the people. Popular opposition against Cruz increased sharply and opposition newspapers started a violent campaign against this and the federal government in general. Members of the parliament and labor unions protested. An anti-vaccination league was organized. On November 10, the Vaccine Revolt exploded in Rio. Violent confrontations with the police ensued, with strikes, barricades,