Psychosensory therapy and texture. Touch is a form of nonverbal communication that can have an extrasensory effect. The use of touch has been long associated with healing. For instance, acupuncture needling, an ancient practice in traditional Chinese medicine (TCM) and a touch therapeutic technique, deals with the insertion of needles into the skin in order to affect one’s mood and perception of pain. Reiki, a Japanese touch technique, deals with movement of hands on the body and is often used for stress reduction. Massage therapy involves kneading different parts of the body with some pressure. This form of touch therapy breaks down
Gene therapy of the human retina efficiently transduces Muller glia following intravitreal injection, and has been used to rescue an animal model of aggressive, autosomal-dominant retinitis pigmentosa. Importantly, the retina is immune-privileged, and thus does not experience a significant inflammation or immune-response when AAV is injected. Immune response to gene therapy vectors is what has caused previous attempts at gene therapy to fail, and is considered a key advantage of gene therapy in the eye. Re-administration has been successful in large animals, indicating that no long-lasting immune response is mounted. Recent data indicates that the subretinal route may be subject to a greater degree of immune