Yellow fever vaccine Foundation to improve the vaccine from the "Asibi" strain, discovered that a favorable chance mutation in the attenuated virus had produced a highly efficacious strain that was named 17D. After field trials in Brazil, over one million people were vaccinated by 1939, without severe complications. For his work on the yellow fever vaccine, Theiler received the 1951 Nobel Prize in Physiology or Medicine. Only the 17D vaccine remains in use today. The outbreak of yellow fever in Angola in January 2016 has raised concerns about whether the global supply of vaccine is adequate to meet the need during a large
Nobel Prize controversies was acceptable for use in humans. No prize was awarded in 1921. Carlos Chagas, who had already been nominated in 1913 and was the recipient of several international awards at the time, was among the nominees. His failure in receiving the award has generated controversy, especially in his homeland, Brazil, proved that Chagas is responsible for one of the most important achievements in the history of parasitology: Chagas alone discovered a new infectious disease, Chagas disease, its pathogen, vector, host, clinical manifestation and epidemology, first describing it in 1909. According to historian Sierra Iglesias, the Nobel Assembly retrieved for Brazilian