Culture of South Africa originated in South Africa. The first human-to-human heart transplant was performed by cardiac surgeon Christiaan Barnard at Groote Schuur Hospital in December 1967. Max Theiler developed a vaccine against Yellow Fever, Allan McLeod Cormack pioneered x-ray Computed tomography, and Aaron Klug developed crystallographic electron microscopy techniques. These advancements were all (with the exception of that of Barnard) recognised with Nobel Prizes. Sydney Brenner won most recently, in 2002, for his pioneering work in molecular biology. Mark Shuttleworth founded an early Internet security company Thawte, that was subsequently bought out by world-leader VeriSign. South Africa has cultivated a burgeoning astronomy community.
Nobel Prize controversies Chen-Ning Yang—by providing him in 1956 with a possible test method for beta decay that worked successfully. Her book "Beta Decay" (1965) is still a sine qua non reference for nuclear physicists. Several Nobel Prizes were awarded for research related to the concepts of the boson, Bose–Einstein statistics and Bose–Einstein condensate—the latest being the 2001 Nobel Prize in Physics given for advancing the theory of Bose–Einstein condensates although Satyendra Nath Bose himself was not awarded the Nobel Prize. In his book "The Scientific Edge", physicist Jayant Narlikar observed: "SN Bose's work on particle statistics (c.1922), which clarified the behavior of