Theiler's encephalomyelitis virus Theiler's encephalomyelitis virus Theiler's Murine Encephalomyelitis Virus (TMEV) is a single-stranded RNA murine cardiovirus from the family "Picornaviridae". It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to Multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for Yellow Fever, for
Franklin A. Neva Franklin A. Neva Franklin Allen Neva (June 8, 1922, Cloquet, Minnesota – October 16, 2011, Billings, Montana) was a virologist and physician who discovered Boston exanthem disease, helped isolate rubella virus, and worked with Jonas Salk on the development of the polio vaccine. He was the first member of the American Society of Tropical Medicine and Hygiene to receive the Ben Kean Medal, in 1995, and also won the Donald Mackay Medal. Neva received his MD from University of Minnesota Medical School in 1946, as part of a Navy training program. He completed his medical residency at Boston City Hospital,