Dr. No (film) stylised main title sequence, both of which were created by Maurice Binder. It also established the iconic "James Bond" theme music. Production designer Ken Adam established an elaborate visual style that is one of the hallmarks of the film series. John Strangways, the British MI6 Station Chief in Jamaica, and his secretary are ambushed and killed. The assassins steal documents related to "Crab Key" and "Doctor No". In response, M, the head of MI6, instructs agent James Bond to investigate Strangways' disappearance and to determine whether it is related to his co-operation with the American Central Intelligence Agency (CIA) on
Motifs in the James Bond film series whom he makes his "immortal introduction". It was Sean Connery's second line in the film. Following the release of "Dr. No", the quote "Bond ... James Bond", became a catch phrase that entered the lexicon of Western popular culture: writers Cork and Scivally said of the introduction in "Dr. No" that the "signature introduction would become the most famous and loved film line ever". In 2001 it was voted as the "best-loved one-liner in cinema" by British cinema goers. On 21 June 2005, the line was honoured as the 22nd historically greatest cinema quotation by the American Film Institute, in