Propolis while also collecting water and tree resin necessary for the production of propolis. The chemical composition and nature of propolis depend on environmental conditions and harvested resources. For centuries, beekeepers assumed that bees sealed the beehive with propolis to protect the colony from the elements, such as rain and cold winter drafts. However, 20th century research revealed that bees not only survive, but also thrive, with increased ventilation during the winter months throughout most temperate regions of the world. Propolis properties may include: The composition of propolis varies from hive to hive, from district to district, and from season to
Substance-related disorder recently published DSM-5 combined substance abuse and substance dependence into a single continuum; this is simply known as substance use disorder and requires more presenting symptoms before a diagnosis is made. It also considers each different substance as its own separate disorder, based upon the same basic criteria. It also distinguishes the difference between dependence and addictions as two separate disorders, not to be confused. There are many potential complications that can arise due to substance abuse such as severe physiological damage, psychological changes and social changes that are often not desirable. Physiological damage is often the most obvious, observed