Center for Drug Evaluation and Research growing crisis around HIV testing and treatment and an inter-agency dispute between officials from the former Bureau of Drugs and officials from the former Bureau of Biologics over whether to approve Genentech's Activase (tissue plasminogen activator) led to the split. In its original form, CDER was composed of six offices: Management, Compliance, Drug Standards, Drug Evaluation I, Drug Evaluation II, Epidemiology and Biostatistics, and Research Resources. The Division of Antiviral Products was added in 1989 under Drug Evaluation II due to the large amount of drugs proposed for treating AIDS. The Office of Generic Drugs was also formed. In 2002,
Egyptian medical papyri making it the lengthiest of the medical papyri. The papyrus covers many different topics including; dermatology, digestive diseases, traumatic diseases, dentistry and gynecological conditions. It makes many references to treating ailments with spells or religious techniques. One of the most important findings of this papyrus are the references to migraines which shows the condition dates back to this time. The "Hearst Papyrus" was offered in 1901 to the Hearst Expedition in Egypt. It is dated around 2000 BC, though doubts subsist about its authenticity. It concentrated on treatments for problems dealing with the urinary system, blood, hair, and bites. It