Hive management in early spring to speed up brood production. Propolis is another byproduct of the bee hive. Certain races of bees are more prone to using propolis. Propolis can be collected on special plastic propolis screens. The tendency of the bees is to use propolis as a glue to seal openings that are too small for a bee to crawl through. A propolis screen is usually put in place of an inner cover. It has small openings that are propolized by the bees. The propolis screen can be frozen which hardens the propolis. Once the propolis is frozen it can be
Substance dependence Substance dependence Substance dependence, also known as drug dependence, is an adaptive state that develops from repeated drug administration, and which results in withdrawal upon cessation of drug use. A "drug addiction", a distinct concept from substance dependence, is defined as compulsive, out-of-control drug use, despite negative consequences. An "addictive drug" is a drug which is both rewarding and reinforcing. ΔFosB, a gene transcription factor, is now known to be a critical component and common factor in the development of virtually all forms of behavioral addiction and drug addictions, but not dependence. Within the framework of the 4th edition of