Propolis with control of "Candida albicans" and immunomodulatory effects. Propolis is used by some string instrument makers (violin, viola, cello and bass) as a varnish ingredient. Some workers use it to seal the surface of newly made bridges. Propolis was purportedly used by Antonio Stradivari in the varnish of his instruments. Propolis is used by some chewing gum manufacturers to make propolis gum. Propolis is used to bring about a chemical reaction to convert fats and oils into automobile wax during application. Propolis Propolis or bee glue is a resinous mixture that honey bees produce by mixing saliva and beeswax with
Substance dependence Substance dependence Substance dependence, also known as drug dependence, is an adaptive state that develops from repeated drug administration, and which results in withdrawal upon cessation of drug use. A "drug addiction", a distinct concept from substance dependence, is defined as compulsive, out-of-control drug use, despite negative consequences. An "addictive drug" is a drug which is both rewarding and reinforcing. ΔFosB, a gene transcription factor, is now known to be a critical component and common factor in the development of virtually all forms of behavioral addiction and drug addictions, but not dependence. Within the framework of the 4th edition of