Interbreeding between archaic and modern humans been shown that Neanderthal ancestry has been selected against in conserved biological pathways, such as RNA processing. Consistent with the hypothesis that purifying selection has reduced Neanderthal contribution in present-day modern human genomes, Upper Paleolithic Eurasian modern humans (such as the Tianyuan modern human) carry more Neanderthal DNA (about 4–5%) than present-day Eurasians modern humans (about 1–2%). Genes affecting keratin were found to have been introgressed from Neanderthals into modern humans (shown in East Asians and Europeans), suggesting that these genes gave a morphological adaptation in skin and hair to modern humans to cope with non-African environments. This is likewise
Mr. and Mrs. Is the Name ram into her arms. The two mer-characters who find a treasure trove resemble Buddy and Cookie, but are not actually named. This may be Buddy's first color appearance, but whether it was intended as an official part of his sub-series is in doubt. It is frequently stated that Buddy was featured in 23 animated films. They would be 24 if "Mr. and Mrs. Is the Name" is included. Mr. and Mrs. Is the Name Mr. and Mrs. Is the Name is a 1935 animated "Merrie Melodies" cartoon, starring Buddy and Cookie (as two mer-kids), and is noted to be the