Ovine pulmonary adenocarcinoma as an animal model for human lung cancer, because OPA is histologically similar to human adenocarcinoma in situ of the lung. Dolly the sheep, the first mammal successfully cloned from an adult somatic cell, was euthanized after it was confirmed that she had OPA. Ovine pulmonary adenocarcinoma Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV). The disease has a long incubation period, and therefore signs usually occur in adult animals (over 2
Pack animal Pack animal A pack animal or beast of burden is an individual or type of working animal used by humans as means of transporting materials by attaching them so their weight bears on the animal's back, in contrast to draft animals which pull loads but do not carry them. Traditional pack animals are diverse including camels, goats, yaks, reindeer, water buffaloes, and llamas as well as the more familiar pack animals like horses, donkeys and mules. The term "pack animal" is traditionally used in contrast to "draft animal", which is a working animal that typically pulls a load behind itself