Mesopotamia Mesopotamia Mesopotamia is a historical region in Western Asia situated within the Tigris–Euphrates river system, in modern days roughly corresponding to most of Iraq, Kuwait, parts of Northern Saudi Arabia, the eastern parts of Syria, Southeastern Turkey, and regions along the Turkish–Syrian and Iran–Iraq borders. The Sumerians and Akkadians (including Assyrians and Babylonians) dominated Mesopotamia from the beginning of written history (c. 3100 BC) to the fall of Babylon in 539 BC, when it was conquered by the Achaemenid Empire. It fell to Alexander the Great in 332 BC, and after his death, it became part of the Greek Seleucid
Geography of Mesopotamia was similarly known as "Gu-gubba" (Akkadian "Kisad tamtim") "bank of the sea." A more comprehensive name of southern Mesopotamia was "Kengi", "the land," or "Kengi Sumer", "the land of Sumer". Sumer has been supposed to be the original of the Biblical Shinar and the Sankhar of the Amarna letters. Opposed to Kengi and Sumer were Urra (Un) and Akkad or northern Babylonia. The original meaning of Urra was perhaps "clayey soil," but it came to signify "the upper country" or "highlands," "kengi" being "the lowlands." In Semitic times, Urra was pronounced Un and confounded with "uru", "city" as a geographical