Southern Illinois Southern Illinois Southern Illinois (also known as "Little Egypt") is the southern third of the state of Illinois. The southern part of Illinois has a unique cultural and regional history. Part of downstate Illinois, the Southern Illinois region is bordered by the two most voluminous rivers in the United States: the Mississippi River and its connecting Missouri River to the west, and the Ohio River to the east and south with the Wabash as tributary. Southern Illinois' most populated city is Belleville at 44,478. Other principal cities include Alton, Centralia, Collinsville, Edwardsville, Effingham, O'Fallon, Harrisburg, Herrin, Mt. Vernon, Marion, and
Big Sandy Creek (Illinois) two streams combine shortly before discharging into the Illinois River opposite the hamlet of Montezuma, Illinois. Sand discharged by the alluvial creeks may have helped form McEvers Island, a silt island in the Illinois River just below the mouth of the creek. Big Sandy Creek (Illinois) Big Sandy Creek, often called the "Big Branch", is a tributary of the Illinois River in central Illinois. It drains a large portion of southwestern Morgan County and southern Scott County. The drainage of Big Sandy Creek includes Lake Jacksonville and the county seat of Scott County, Winchester, Illinois. Most of the Big Sandy