Ohio River course forms the northern borders of West Virginia and Kentucky; and the southern borders of Ohio, Indiana and Illinois, until it joins the Mississippi River at the city of Cairo, Illinois. Where the Ohio joins the Mississippi is the lowest elevation in the state of Illinois, at . The Ohio River, which flows westward from Pittsburgh, Pennsylvania, to Cairo, Illinois, is the largest tributary, by volume, of the Mississippi River in the United States. At the confluence, the Ohio is considerably bigger than the Mississippi. Measured by long-term mean discharge in cubic feet per second and cubic meters per second,
Muddy Creek (Lamine River) Muddy Creek (Lamine River) Muddy Creek is a stream in Johnson and Pettis Counties in the U.S. state of Missouri. It is a tributary of Lamine River. The stream headwaters arise in southeastern Johnson County just east of the community of Sutherland and Missouri Route 23 at . The stream flows northeast and enters Pettis County about three miles southeast of Whiteman Air Force Base. The stream continues to the northeast passing under Missouri Route 127 three miles south of LaMonte and under U.S. Route 50 three miles west of Sedalia. It crosses under U.S. Route 65 six miles north