Ovine rinderpest virus does not infect humans. This disease was first described in 1942 in Côte d'Ivoire. Now, PPR has spread to more than 70 countries in the world. In 2017, the disease was reported to be affecting saiga in Mongolia, causing near-catastrophic herd depletion for the endangered species. In 2018, the disease was reported to be in Bulgaria close to the border with Turkey. PPR is also known as goat plague, "kata", syndrome of stomatitis-pneumoenteritis, and ovine rinderpest. Official agencies such as the FAO and OIE use the French name ""peste des petits ruminants"" with several spelling variants. Symptoms are similar
Alternatives to animal testing Medical Experiments that despite the use of microdosing, "animal studies will still be required". Guiding principles for more ethical use of animals in testing are the Three Rs (3Rs) first described by Russell and Burch in 1959. These principles are now followed in many testing establishments worldwide. Cell culture can be an alternative to animal use in some cases. For example, cultured cells have been developed to create monoclonal antibodies; prior to this, production required animals to undergo a procedure likely to cause pain and distress. However, even though cell or tissue culture methods may reduce the number of experiments