Ohio River course forms the northern borders of West Virginia and Kentucky; and the southern borders of Ohio, Indiana and Illinois, until it joins the Mississippi River at the city of Cairo, Illinois. Where the Ohio joins the Mississippi is the lowest elevation in the state of Illinois, at . The Ohio River, which flows westward from Pittsburgh, Pennsylvania, to Cairo, Illinois, is the largest tributary, by volume, of the Mississippi River in the United States. At the confluence, the Ohio is considerably bigger than the Mississippi. Measured by long-term mean discharge in cubic feet per second and cubic meters per second,
Big Muddy Creek (Missouri River tributary) Fort Peck Indian Reservation. It joins the Missouri west of Culbertson. It was explored in 1805 by the Lewis and Clark Expedition, who called it Martha's River in their journals and noticed on their return voyage in 1806 that it had changed its mouth on the Missouri. Along with the Milk River and the Poplar River, it is one of three waterways in Canada that drain into the Gulf of Mexico. Big Muddy Creek has also been known as: Big Muddy River, Little Yellow River, Martha River, Martha's River, Marthas River, Marthy's River and Park River. Big Muddy Creek (Missouri