Discrimination against drug addicts that suffer with an addiction, only a few will receive treatment due to the complexity of health care systems. Most health care systems do not have insurance coverage for addiction recovery and many health care providers have little to no training in treating addiction. Some doctors do not feel comfortable treating an addiction due to their lack of knowledge and training of the topic. This is one of the reasons why drug dependence is difficult to recover from. Among injecting drug users, the incidence of HIV infection is higher than among other drug addicts, however punitive and discriminatory measures against
Small molecule drug conjugate linker systems and drug payloads and generate SMDCs for different diseases. The most advanced SMDC is vintafolide, a derivative of the anti-mitotic chemotherapy drug vinblastine which is chemically linked to folic acid. SMDCs are currently being developed by Endocyte for treating cancer, inflammatory diseases and kidney disease, as well as a companion imaging agent that is created by replacing the potent drug with an imaging agent. Small molecule drug conjugate Small molecule drug conjugates or SMDCs are built with three modules: a targeting ligand, a linker and a drug payload. The targeting ligands consist of low molecular weight, high-affinity ligands