Ovine pulmonary adenocarcinoma Ovine pulmonary adenocarcinoma Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV). The disease has a long incubation period, and therefore signs usually occur in adult animals (over 2 years of age). Clinical signs resemble a non-specific progressive pneumonia, including poor body condition and, particularly after exercise, respiratory difficulty. Unless a concurrent lung infection is present, affected sheep continue to eat. The only sign specific to OPA is a watery nasal discharge, consisting
Animal welfare of Agriculture Animal and Plant Health Inspection Service (APHIS) enforces the Animal Welfare Act. APHIS inspects animal research facilities regularly and reports are published online. According to the U.S. Department of Agriculture (USDA), the total number of animals used in the U.S. in 2005 was almost 1.2 million, but this does not include rats, mice, and birds which are not covered by welfare legislation but make up approximately 90% of research animals. There are many different approaches to describing and defining animal welfare. Positive conditions - Providing good animal welfare is sometimes defined by a list of positive conditions which