History of decompression research and development gets too high when compared to the ambient pressure. These bubbles, and products of injury caused by the bubbles, can cause damage to tissues known as "decompression sickness" or "the bends". The immediate goal of controlled decompression is to avoid development of symptoms of bubble formation in the tissues of the diver, and the long-term goal is to also avoid complications due to sub-clinical decompression injury. The symptoms of decompression sickness are known to be caused by damage resulting from the formation and growth of bubbles of inert gas within the tissues and by blockage of arterial blood supply to
Ratio decompression by the body from breathing gases under pressure has never been definitively established, particularly in relation to the formation of bubbles in the body's tissues, and a number of different algorithms have been developed over the years, based on simplified hypotheses of gas transport and absorption in body tissues, modified to fit empirical data, to predict the rate of off-gassing to reduce the risk of decompression sickness in divers to an acceptable level. However, these models do not describe the individual physiology of the diver accurately: divers have been known to suffer symptomatic decompression sickness whilst diving within the limits