Propolis Propolis Propolis or bee glue is a resinous mixture that honey bees produce by mixing saliva and beeswax with exudate gathered from tree buds, sap flows, or other botanical sources. It is used as a sealant for unwanted open spaces in the hive. Propolis is used for small gaps (approximately or less), while larger spaces are usually filled with beeswax. Its color varies depending on its botanical source, with dark brown as the most common. Propolis is sticky at and above , while at lower temperatures, it becomes hard and brittle. While foraging, worker bees primarily harvest pollen and nectar,
Substance-related disorder recently published DSM-5 combined substance abuse and substance dependence into a single continuum; this is simply known as substance use disorder and requires more presenting symptoms before a diagnosis is made. It also considers each different substance as its own separate disorder, based upon the same basic criteria. It also distinguishes the difference between dependence and addictions as two separate disorders, not to be confused. There are many potential complications that can arise due to substance abuse such as severe physiological damage, psychological changes and social changes that are often not desirable. Physiological damage is often the most obvious, observed