Ohio River course forms the northern borders of West Virginia and Kentucky; and the southern borders of Ohio, Indiana and Illinois, until it joins the Mississippi River at the city of Cairo, Illinois. Where the Ohio joins the Mississippi is the lowest elevation in the state of Illinois, at . The Ohio River, which flows westward from Pittsburgh, Pennsylvania, to Cairo, Illinois, is the largest tributary, by volume, of the Mississippi River in the United States. At the confluence, the Ohio is considerably bigger than the Mississippi. Measured by long-term mean discharge in cubic feet per second and cubic meters per second,
Muddy River (Washington) 83 and passes the Ape Canyon Trailhead and the Lava Canyon Interpretive Site, both on the left, before entering Muddy River Gorge. Flowing northeast through the gorge, the stream plunges over three waterfalls before emerging from the narrows and curving sharply again to the southeast. Here Crane Lake is on the left, Smith Creek enters from the left, and Smith Creek Trailhead is on the right. Slightly downstream of the trailhead, the river leaves the national volcanic monument but remains in the national forest. At about the level, Clearwater Creek enters from the left. Turning south, the river descends less