Ovine pulmonary adenocarcinoma be predisposed to OPA. Most affected sheep show signs at 2 to 4 years of age. OPA is not a notifiable disease, and therefore it is difficult to assess its prevalence. OPA was first described in the UK in 1888, and described in detail in South Africa in 1891. The disease was initially known as "jaagsiekte" , a word derived from Afrikaans, meaning "chasing sickness," so called because animals are in respiratory distress as if they are out of breath from being chased. It has also been known as sheep pulmonary adenomatosis and ovine pulmonary carcinoma. OPA has been used
Animal Jam Although Animal Jam is primarily played online, the Animal Jam universe has been expanded to incorporate mobile devices such as smartphones, tablets, and iOS devices. The most popular Animal Jam mobile app is "Play Wild" which is a 3D version of the Animal Jam world. However, WildWorks has also developed other apps that are based on the Animal Jam game. Animal Jam was developed by WildWorks and it was launched on September 9, 2010. In 2011, Animal Jam had over 1 million registered players in the game. Later, in March 2013, the game had already achieved over 10 million players,