Ovine pulmonary adenocarcinoma Ovine pulmonary adenocarcinoma Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV). The disease has a long incubation period, and therefore signs usually occur in adult animals (over 2 years of age). Clinical signs resemble a non-specific progressive pneumonia, including poor body condition and, particularly after exercise, respiratory difficulty. Unless a concurrent lung infection is present, affected sheep continue to eat. The only sign specific to OPA is a watery nasal discharge, consisting
Animal cracker popular, the Austin variety has similar nutritional content and animal shapes. The Austin product is labeled under the name of the Kellogg Company, which acquired Keebler in 2001. Stauffer Biscuit Company of York, Pennsylvania, also has a line of animal crackers, which are now distributed by several major discount retailers. Their use of the spices nutmeg and mace give the basic animal cracker a slightly different character from the Nabisco crackers. The Borden corporation also produced a brand of animal crackers, until the late 1970s. They came in a red box, which featured the famous Elsie the Cow logo. Market