Ovine pulmonary adenocarcinoma be predisposed to OPA. Most affected sheep show signs at 2 to 4 years of age. OPA is not a notifiable disease, and therefore it is difficult to assess its prevalence. OPA was first described in the UK in 1888, and described in detail in South Africa in 1891. The disease was initially known as "jaagsiekte" , a word derived from Afrikaans, meaning "chasing sickness," so called because animals are in respiratory distress as if they are out of breath from being chased. It has also been known as sheep pulmonary adenomatosis and ovine pulmonary carcinoma. OPA has been used
Animal welfare in the United Kingdom Animal welfare in the United Kingdom Animal welfare in the United Kingdom relates to the treatment of animals in fields such as agriculture, hunting, medical testing and the domestic ownership of animals. It is distinct from animal conservation. The Animal Welfare Act 2006 is the latest animal welfare legislation in England and Wales. It superseded and consolidated more than 20 other pieces of legislation, such as the Protection of Animals Act 1934 and the Abandonment of Animals Act 1960. The 2006 Act introduced tougher penalties for neglect and cruelty, including fines of up to £20,000, a maximum jail term of