Ohio River course forms the northern borders of West Virginia and Kentucky; and the southern borders of Ohio, Indiana and Illinois, until it joins the Mississippi River at the city of Cairo, Illinois. Where the Ohio joins the Mississippi is the lowest elevation in the state of Illinois, at . The Ohio River, which flows westward from Pittsburgh, Pennsylvania, to Cairo, Illinois, is the largest tributary, by volume, of the Mississippi River in the United States. At the confluence, the Ohio is considerably bigger than the Mississippi. Measured by long-term mean discharge in cubic feet per second and cubic meters per second,
Muddy Run (West Branch Susquehanna River tributary) Muddy Run (West Branch Susquehanna River tributary) Muddy Run is a tributary of the West Branch Susquehanna River in Northumberland County, Pennsylvania, in the United States. It is in length. The creek is several miles northeast of the community of Milton. Main land uses include agricultural land and forest. The area of the creek's watershed is 11.4 square miles, most of which is agricultural land. Muddy Run is entirely within Turbot Township. Most of the rock in the watershed is shale. The most common soil series is the Berks-Weikert-Bedington series. Muddy Run begins in a valley in eastern Turbot Township,