Horsefeather (cocktail) Horsefeather (cocktail) A Horsefeather is a whiskey cocktail. It was invented in Lawrence, Kansas in the 1990s. It remains a regional drink in the Kansas City region. The drink is an iteration of the classic cocktail Horse's Neck and is similar to a Moscow Mule. A horsefeather is traditionally rye whiskey or blended whiskey, ginger beer, three dashes of Angostura bitters, and a little lemon juice. A highball glass is filled 3/4 with ice. The ingredients are then poured into the glass and stirred. There are many variations such as substituting ginger beer with ginger ale, adding cherries, muddling the
Cooperstown cocktail Cooperstown cocktail The Cooperstown cocktail refers to a panel of four drug probes used in human pharmacokinetic studies to determine the activity of drug metabolising enzymes. The terminology 'cocktail' refers to the fact that the drug probes are given together. The Cooperstown cocktail consists of four drugs that are considered specific substrates for four cytochrome P450 (CYP) isoforms. One of the drugs (caffeine) provides, through its metabolites, substrates for two additional enzymes (see next paragraph). The drugs and the enzymes they probe are as follows - caffeine (probes CYP1A2, N-acetyltransferase 2, xanthine oxidase), midazolam (probes CYP3A), omeprazole (probes CYP2C19) and