Decompression (diving) but in later experiments signs of what was later to become known as decompression sickness were observed. Later, when technological advances allowed the use of pressurization of mines and caissons to exclude water ingress, miners were observed to present symptoms of what would become known as caisson disease, compressed air illness, the bends, and decompression sickness. Once it was recognized that the symptoms were caused by gas bubbles, and that re-compression could relieve the symptoms, Paul Bert showed in 1878 that decompression sickness is caused by nitrogen bubbles released from tissues and blood during or after decompression, and showed the
Ratio decompression by the body from breathing gases under pressure has never been definitively established, particularly in relation to the formation of bubbles in the body's tissues, and a number of different algorithms have been developed over the years, based on simplified hypotheses of gas transport and absorption in body tissues, modified to fit empirical data, to predict the rate of off-gassing to reduce the risk of decompression sickness in divers to an acceptable level. However, these models do not describe the individual physiology of the diver accurately: divers have been known to suffer symptomatic decompression sickness whilst diving within the limits