Dr. No (film) stylised main title sequence, both of which were created by Maurice Binder. It also established the iconic "James Bond" theme music. Production designer Ken Adam established an elaborate visual style that is one of the hallmarks of the film series. John Strangways, the British MI6 Station Chief in Jamaica, and his secretary are ambushed and killed. The assassins steal documents related to "Crab Key" and "Doctor No". In response, M, the head of MI6, instructs agent James Bond to investigate Strangways' disappearance and to determine whether it is related to his co-operation with the American Central Intelligence Agency (CIA) on
James Bond greatest film hero. He was also placed at number 11 on a similar list by "Empire" and as the fifth greatest movie character of all time by "Premiere". The 23 James Bond films produced by Eon Productions, which have grossed $4,910 million in box office returns alone, have made the series one of the highest-grossing ever. It is estimated that since "Dr. No", a quarter of the world's population have seen at least one Bond film. The UK Film Distributors' Association have stated that the importance of the Bond series of films to the British film industry cannot be overstated,