Decriminalization of non-medical cannabis in the United States drug, which contains a very active component delta-9-tetrahydrocannabinol (THC). For thousands of years, it was used for medical purposes in many different parts of the world. Recent studies also agreed that THC had great potential benefits for medical purposes. A number of patients who have HIV, multiple sclerosis (MS), neuropathic chronic pain, and cancer were under medical marijuana treatment. The treatments could either be smoke on cannabis or oral preparations, which were synthetic THC and synthetic equivalent. According to Medical Uses of Marijuana (Cannabis sativa), patients with HIV reported that the drug reduced mixed neuropathic pain more significantly in comparison
Botulinum toxin FDA approves the text of the labels of prescription medicines. The FDA approves which medical conditions the drug manufacturer may sell the drug for. However, those approved by the FDA to prescribe these drugs may freely prescribe them for any condition they wish, called off-label use. Botulinum toxins have been used off-label for several pediatric conditions, including infantile esotropia. Khalaf Bushara and David Park were the first to demonstrate a nonmuscular use of BTX-A while treating patients with hemifacial spasm in England in 1993, showing that botulinum toxin injections inhibit sweating, and so are useful in treating hyperhidrosis (excessive sweating).