Matjiesfontein surrounding Karoo region is a flat, sparsely populated semi-desert. Matjiesfontein has a healthy climate for people with lung complaints, and was once home to a Victorian spa and health resort. Matjiesfontein Matjiesfontein is a settlement in Central Karoo District Municipality in the Western Cape province of South Africa. The original inhabitants of the region were the Khoikhoi herders and the San hunter gatherers. Following the arrival of the early European colonists, the area was settled by Afrikaaner Trekboers and Griqua people. The town itself owes its existence to the Cape Government Railways, and to the route that their founder, Cape
Karoo which is Afrikaans for Little Karoo. The Great Karoo straddles the 30° S parallel on the west of the continent, in a similar position to other semidesert areas on earth, north and south of the equator. It is furthermore in the rainfall shadow of the Cape Fold Mountains along the western coastline. The western "Lower Karoo" (the Tankwa Karoo and Moordenaarskaroo) contain remnants of the Cape Fold Mountains (e.g. the Witteberg and Anysberg Mountains) which give it a moderate hilly appearance, but further east, the Lower Karoo becomes a monotonously flat plain. The "Upper Karoo" has been intruded by dolerite