Dr. No (novel) No" was serialised in the "Daily Express", first in an abridged story form and later as a comic strip. The story was adapted in 1962 as the first film in the Bond series, with Sean Connery in the lead role; in 2008 BBC Radio 4 broadcast a version, with Toby Stephens as Bond. After recovering from serious poisoning inflicted by the SMERSH agent Rosa Klebb (in "From Russia, with Love") the MI6 agent James Bond is sent by his superior, M, on an undemanding mission to the British Colony of Jamaica. He is instructed to investigate the disappearance of Commander
Dr. No (film) designed a highly stylised main title sequence, a theme that has been repeated in the subsequent Eon-produced Bond films. Binder's budget for the title sequence was £2,000 (£ in ). The character James Bond was introduced towards, but not at, the beginning of the film in a "now-famous nightclub sequence featuring Sylvia Trench", to whom he makes his "immortal introduction". The introduction to the character in "Le Cercle at Les Ambassadeurs", an upmarket gambling club, is derived from Bond's introduction in the first novel, "Casino Royale", which Fleming had used because "skill at gambling and knowledge of how to behave