Ovine pulmonary adenocarcinoma as an animal model for human lung cancer, because OPA is histologically similar to human adenocarcinoma in situ of the lung. Dolly the sheep, the first mammal successfully cloned from an adult somatic cell, was euthanized after it was confirmed that she had OPA. Ovine pulmonary adenocarcinoma Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV). The disease has a long incubation period, and therefore signs usually occur in adult animals (over 2
Animal cracker popular, the Austin variety has similar nutritional content and animal shapes. The Austin product is labeled under the name of the Kellogg Company, which acquired Keebler in 2001. Stauffer Biscuit Company of York, Pennsylvania, also has a line of animal crackers, which are now distributed by several major discount retailers. Their use of the spices nutmeg and mace give the basic animal cracker a slightly different character from the Nabisco crackers. The Borden corporation also produced a brand of animal crackers, until the late 1970s. They came in a red box, which featured the famous Elsie the Cow logo. Market