Mesopotamia Mesopotamia Mesopotamia is a historical region in Western Asia situated within the Tigris–Euphrates river system, in modern days roughly corresponding to most of Iraq, Kuwait, parts of Northern Saudi Arabia, the eastern parts of Syria, Southeastern Turkey, and regions along the Turkish–Syrian and Iran–Iraq borders. The Sumerians and Akkadians (including Assyrians and Babylonians) dominated Mesopotamia from the beginning of written history (c. 3100 BC) to the fall of Babylon in 539 BC, when it was conquered by the Achaemenid Empire. It fell to Alexander the Great in 332 BC, and after his death, it became part of the Greek Seleucid
Geography of Mesopotamia country, Nineveh, Kalaḫ and Arbela, were all on the east bank of the Tigris. The reason was its abundant supply of water, whereas the great plain on the western side had to depend on streams flowing into the Euphrates. Mesopotamia means "(Land) between two rivers" in ancient Greek. The oldest known occurrence of the name Mesopotamia dates to the 4th century BCE, when it was used to designate the land east of the Euphrates in north Syria. In modern times it has been more generally applied to all the lands between the Euphrates and the Tigris, thereby incorporating not only