Ovine pulmonary adenocarcinoma be predisposed to OPA. Most affected sheep show signs at 2 to 4 years of age. OPA is not a notifiable disease, and therefore it is difficult to assess its prevalence. OPA was first described in the UK in 1888, and described in detail in South Africa in 1891. The disease was initially known as "jaagsiekte" , a word derived from Afrikaans, meaning "chasing sickness," so called because animals are in respiratory distress as if they are out of breath from being chased. It has also been known as sheep pulmonary adenomatosis and ovine pulmonary carcinoma. OPA has been used
Animal cafe in Taiwan, they were initially popularized in Japan. One Japanese tourist visited Taiwan and discovered the potential of animal cafe. Then he came back to Japan and established the first animal cafe in Osaka in 2004. Nowadays, Japan is known as the country which has the most animal cafes in the world. Although there are some countries in Europe and America which also have animal cafes such as Spain, Germany, France, United States, Australia. United Kingdoms etc, animal cafes are still more popular in Asian countries yet. When the animal cafe was first created in Taiwan and Japan, it was