Decompression (diving) but in later experiments signs of what was later to become known as decompression sickness were observed. Later, when technological advances allowed the use of pressurization of mines and caissons to exclude water ingress, miners were observed to present symptoms of what would become known as caisson disease, compressed air illness, the bends, and decompression sickness. Once it was recognized that the symptoms were caused by gas bubbles, and that re-compression could relieve the symptoms, Paul Bert showed in 1878 that decompression sickness is caused by nitrogen bubbles released from tissues and blood during or after decompression, and showed the
Decompression sickness good blood supply) actually increasing their total inert gas loading. This is often found to provoke inner ear decompression sickness, as the ear seems particularly sensitive to this effect. The location of micronuclei or where bubbles initially form is not known. The most likely mechanisms for bubble formation are tribonucleation, when two surfaces make and break contact (such as in joints), and heterogeneous nucleation, where bubbles are created at a site based on a surface in contact with the liquid. Homogeneous nucleation, where bubbles form within the liquid itself is less likely because it requires much greater pressure differences than