Amount of substance in use in chemical engineering in the United States is the pound-mole, having the symbol lb-mol. One pound-mole is . When quoting an amount of substance, it is necessary to specify the entity involved, unless there is no risk of ambiguity. One mole of chlorine could refer either to chlorine atoms, as in 58.44 g of sodium chloride, or to chlorine molecules, as in 22.711 liters of chlorine gas at STP. The simplest way to avoid ambiguity is to replace the term "substance" by the name of the entity or to quote the empirical formula. For example: Amount of substance
Substance of very high concern must be submitted to the ECHA. Substance of very high concern A substance of very high concern (SVHC) is a chemical substance (or part of a group of chemical substances) for which it has been proposed that the use within the European Union be subject to authorisation under the REACH Regulation. Indeed, listing of a substance as an SVHC by the European Chemicals Agency (ECHA) is the first step in the procedure for restriction of use of a chemical. The first list of SVHCs was published on 28 October 2008 and the list has been updated many times to include