Propolis recently been isolated from red propolis, and prenylated acids such as 4-hydroxy-3,5-diprenyl cinnamic acid have been documented. An analysis of propolis from Henan, China found sinapinic acid, isoferulic acid, caffeic acid, and chrysin, with the first three compounds demonstrating antibacterial properties. Also, Brazilian red propolis, largely derived from "Dalbergia ecastaphyllum" plant resin, has high relative percentages of the isoflavonoids 3-hydroxy-8,9-dimethoxypterocarpan and medicarpin. Other flavonoids commonly present include galangin and pinocembrin. Caffeic acid phenethyl ester (CAPE) is also a component of some varieties of propolis from New Zealand. Occasionally, worker bees will even gather various caulking compounds of human manufacture, when
Substance-related disorder Substance-related disorder Substance abuse, also known as drug abuse, is a patterned use of a substance (drug) in which the user consumes the substance in amounts or with methods which are harmful to themselves or others. The drugs used are often associated with levels of intoxication that alter judgment, perception, attention and physical control, not related with medical effects. It is often thought that the main abused substances are illegal drugs and alcohol; however it is becoming more common that prescription drugs and tobacco are a prevalent problem. Substance-related disorders, including both substance dependence and substance abuse, can lead to