History of decompression research and development range of commercial, military and recreational diving. The first recorded experimental work related to decompression was conducted by Robert Boyle, who subjected experimental animals to reduced ambient pressure by use of a primitive vacuum pump. In the earliest experiments the subjects died from asphyxiation, but in later experiments, signs of what was later to become known as decompression sickness were observed. Later, when technological advances allowed the use of pressurisation of mines and caissons to exclude water ingress, miners were observed to present symptoms of what would become known as caisson disease, the bends, and decompression sickness. Once it was
Isobaric counterdiffusion in the literature by Harvey in 1977 as divers switched from a nitrogen mixture to a helium mixture (diffusivity of helium is 2.65 times faster than nitrogen), they quickly developed itching followed by joint pain. Saturation divers breathing hydreliox switched to a heliox mixture and developed symptoms of decompression sickness during Hydra V. More recently, Doolette and Mitchell have described ICD as the basis for inner ear decompression sickness and suggest "breathing-gas switches should be scheduled deep or shallow to avoid the period of maximum supersaturation resulting from decompression". It can also happen when saturation divers breathing hydreliox switch to