Testicle fetal abdomen to the inguinal ring and beyond to the inguinal canal and into the scrotum. In most cases (97% full-term, 70% preterm), both testes have descended by birth. In most other cases, only one testis fails to descend (cryptorchidism) and that will probably express itself within a year. The testes grow in response to the start of spermatogenesis. Size depends on lytic function, sperm production (amount of spermatogenesis present in testis), interstitial fluid, and Sertoli cell fluid production. After puberty, the volume of the testes can be increased by over 500% as compared to the pre-pubertal size. Testicles are
Users' Guides to the Medical Literature guides to the medical literature, IX: a method for grading health care recommendations. JAMA, 274, pp. 1800–1804. Giacomini, M.K. & Cook, D.J., 2000. Users’ Guides to the Medical Literature: XXIII. Qualitative Research in Health Care A. Are the Results of the Study Valid? JAMA, 284(3), pp. 357–362. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.284.3.357 Giacomini, M.K. & Cook, D.J., 2000. Users’ Guides to the Medical Literature: XXIII. Qualitative Research in Health Care B. What Are the Results and How Do They Help Me Care for My Patients? JAMA, 284(4), pp. 478–482. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.284.4.478. Guyatt, G., Sackett, D. & Cook, D., 1993. Users’ guides