History of decompression research and development gets too high when compared to the ambient pressure. These bubbles, and products of injury caused by the bubbles, can cause damage to tissues known as "decompression sickness" or "the bends". The immediate goal of controlled decompression is to avoid development of symptoms of bubble formation in the tissues of the diver, and the long-term goal is to also avoid complications due to sub-clinical decompression injury. The symptoms of decompression sickness are known to be caused by damage resulting from the formation and growth of bubbles of inert gas within the tissues and by blockage of arterial blood supply to
Physiology of decompression the sampling used in decompression studies to identify highly reflective gas bubbles. Detection of venous gas bubbles by ultrasound imaging is a sensitive, but not specific, predictor of adverse effects of decompression, similar to the published relationship between Doppler detected bubbles and decompression sickness. The correlation between Doppler-detected intravascular bubbles and decompression sickness is that almost all divers who developed DCS after a dive produced large numbers of bubbles, but even grade 3 or 4 bubbles could manifest without signs or symptoms of DCS, and grades 0, 1 and 2 bubbles are associated with very low risk. In a series