Southern Illinois Southern Illinois Southern Illinois (also known as "Little Egypt") is the southern third of the state of Illinois. The southern part of Illinois has a unique cultural and regional history. Part of downstate Illinois, the Southern Illinois region is bordered by the two most voluminous rivers in the United States: the Mississippi River and its connecting Missouri River to the west, and the Ohio River to the east and south with the Wabash as tributary. Southern Illinois' most populated city is Belleville at 44,478. Other principal cities include Alton, Centralia, Collinsville, Edwardsville, Effingham, O'Fallon, Harrisburg, Herrin, Mt. Vernon, Marion, and
Muddy River (Nevada) By 1855 it had become a cold season freight route between Utah and Southern California that remained in use in Southern Nevada into the 20th century. Mormon settlers established several settlements in the Muddy River area in 1864, including the town of St. Thomas, which by 1938 was submerged under Lake Mead until recently. Some of the towns ruins can be still seen during low water levels. Some Paiutes fought to protect and reclaim their homeland. For a variety of reasons, including the harsh climate, unpredictable periods of drought, and a tax dispute with the State of Nevada, the Mormons