Interbreeding between archaic and modern humans been shown that Neanderthal ancestry has been selected against in conserved biological pathways, such as RNA processing. Consistent with the hypothesis that purifying selection has reduced Neanderthal contribution in present-day modern human genomes, Upper Paleolithic Eurasian modern humans (such as the Tianyuan modern human) carry more Neanderthal DNA (about 4–5%) than present-day Eurasians modern humans (about 1–2%). Genes affecting keratin were found to have been introgressed from Neanderthals into modern humans (shown in East Asians and Europeans), suggesting that these genes gave a morphological adaptation in skin and hair to modern humans to cope with non-African environments. This is likewise
In the Castle of My Skin In the Castle of My Skin In the Castle of My Skin is the first and much acclaimed novel by Barbadian writer George Lamming, originally published in 1953 by Michael Joseph in London, and subsequently published in New York City by McGraw-Hill. The novel won a Somerset Maugham Award and was championed by eminent figures Jean-Paul Sartre and Richard Wright, the latter writing an introduction to the book's US edition. An autobiographical novel, set in the 1930s–'40s in Carrington Village, Barbados, where the author was born and raised, "In the Castle of My Skin" follows the events in a young