Jaagsiekte sheep retrovirus Jaagsiekte sheep retrovirus Jaagsiekte sheep retrovirus (JSRV) is a betaretrovirus which is the causative agent of a contagious lung cancer in sheep, called ovine pulmonary adenocarcinoma. JSRV is the virus that is the cause of the contagious lung tumors in sheep called ovine pulmonary adenocarcinoma (OPA). The disease has also been called "jaagsiekte", after the Afrikaans words for "chase" ("jaag") and "sickness" ("siekte"), to describe the respiratory distress observed in an animal out of breath from being chased, indicating the breathing difficulty experienced by infected sheep. Transmission of virus is through aerosol spread between sheep. The exogenous infectious form of
Alternatives to animal testing organises an annual conference in Linz (Austria) for The World Congress on Alternatives and Animal Use in the Life Sciences takes place every three years. The next conference (10th) will be held in September 2017 in Seattle. The 1st Latino-Americano Congress on Alternative to Animal Testing took place in 2012. Colama (I Congresso Latino-Americano De Metodos Alternativos Ao Uso De Animais No Ensino, Pesquisa E Industria). On January 1, 2013, EU Directive 2010/63/EU ""on the protection of animals used for scientific purposes"" entered into force for the EU Member States (MS),<ref name="DIRECTIVE 2010/63/EU"></ref> repealing Directive 86/609/EEC. Because it is a