Myotragus of the island of Majorca ("Myotragus pepgonellae") indicate that "Myotragus balearicus", in spite of being a browsing animal, descended originally from grazers. The closest related species to "Myotragus" are ovine, such as the extinct "Nesogoral" of the Plio-Pleistocene of Sardinia, the old "Gallogoral" of France (possible mainland ancestor of both "Myotragus" and "Nesogoral"), "Ovis" (present sheep and mouflon) and the mountain goats of Central Asia. The last ancestor common to "Myotragus" and "Nesogoral" arrived at Majorca and Sardinia around 6 million years ago, a time at which the Straits of Gibraltar were closed and the Mediterranean Sea was a small
Alternatives to animal testing create a model of the human immune system on which the efficacy of new vaccines and other compounds may be tested, replacing some steps of the vaccine development process that would otherwise be performed on animals. This process is faster and more flexible than previous methods but critics worry that it may be too simple to be useful on a large scale. Examples of computer simulations available include models of asthma, though potential new medicines identified using these techniques are currently still required to be verified in animal and human tests before licensing. Computer operated mannequins, also known as crash