Southern Illinois Southern Illinois Southern Illinois (also known as "Little Egypt") is the southern third of the state of Illinois. The southern part of Illinois has a unique cultural and regional history. Part of downstate Illinois, the Southern Illinois region is bordered by the two most voluminous rivers in the United States: the Mississippi River and its connecting Missouri River to the west, and the Ohio River to the east and south with the Wabash as tributary. Southern Illinois' most populated city is Belleville at 44,478. Other principal cities include Alton, Centralia, Collinsville, Edwardsville, Effingham, O'Fallon, Harrisburg, Herrin, Mt. Vernon, Marion, and
Muddy, Illinois Muddy, Illinois Muddy is a small incorporated village located in the Harrisburg Township in Saline County, Illinois, United States. The population was 78 at the 2000 census. During the 19th century, the site of Muddy was home to a small settlement known as Robinson's Ford, which was among the communities considered for the seat of Saline County after the county's creation in the 1840s. The modern village of Muddy had its start as a mining settlement established by the Harrisburg Big Muddy Coal Company, for which it was named, in 1903. The mine was sold to the larger O'Gara Coal