Ovine pulmonary adenocarcinoma as an animal model for human lung cancer, because OPA is histologically similar to human adenocarcinoma in situ of the lung. Dolly the sheep, the first mammal successfully cloned from an adult somatic cell, was euthanized after it was confirmed that she had OPA. Ovine pulmonary adenocarcinoma Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV). The disease has a long incubation period, and therefore signs usually occur in adult animals (over 2
Alternatives to animal testing organises an annual conference in Linz (Austria) for The World Congress on Alternatives and Animal Use in the Life Sciences takes place every three years. The next conference (10th) will be held in September 2017 in Seattle. The 1st Latino-Americano Congress on Alternative to Animal Testing took place in 2012. Colama (I Congresso Latino-Americano De Metodos Alternativos Ao Uso De Animais No Ensino, Pesquisa E Industria). On January 1, 2013, EU Directive 2010/63/EU ""on the protection of animals used for scientific purposes"" entered into force for the EU Member States (MS),<ref name="DIRECTIVE 2010/63/EU"></ref> repealing Directive 86/609/EEC. Because it is a