Matjiesfontein surrounding Karoo region is a flat, sparsely populated semi-desert. Matjiesfontein has a healthy climate for people with lung complaints, and was once home to a Victorian spa and health resort. Matjiesfontein Matjiesfontein is a settlement in Central Karoo District Municipality in the Western Cape province of South Africa. The original inhabitants of the region were the Khoikhoi herders and the San hunter gatherers. Following the arrival of the early European colonists, the area was settled by Afrikaaner Trekboers and Griqua people. The town itself owes its existence to the Cape Government Railways, and to the route that their founder, Cape
Karoo into the increasingly arid Bushmanland towards the north-west. To the north and north-east, it fades into the savannah and grasslands of Griqualand West and the Highveld. The boundary to the east grades into the grasslands of the Eastern Midlands. The Great Karoo is itself divided by the Great Escarpment into the Upper Karoo (generally above 1200–1500 m) and the Lower Karoo on the plains below at 700–800 m. A great many local names, each denoting different subregions of the Great Karoo, exist, some more widely, or more generally, known than others. In the Lower Karoo, going from west to east,