Myotragus of the island of Majorca ("Myotragus pepgonellae") indicate that "Myotragus balearicus", in spite of being a browsing animal, descended originally from grazers. The closest related species to "Myotragus" are ovine, such as the extinct "Nesogoral" of the Plio-Pleistocene of Sardinia, the old "Gallogoral" of France (possible mainland ancestor of both "Myotragus" and "Nesogoral"), "Ovis" (present sheep and mouflon) and the mountain goats of Central Asia. The last ancestor common to "Myotragus" and "Nesogoral" arrived at Majorca and Sardinia around 6 million years ago, a time at which the Straits of Gibraltar were closed and the Mediterranean Sea was a small
Alternatives to animal testing for "Safety Evaluation Ultimately Replacing Animal Testing". It is called "SEURAT-1" to indicate that more steps have to be taken before the final goal will be reached. SEURAT-1 will develop knowledge and technology building blocks required for the development of solutions for the replacement of current repeated dose systemic toxicity testing "in vivo" used for the assessment of human safety. SEURAT-1 is composed of six research projects, which started on January 1, 2011 and will run for five years. These projects will closely cooperate with a common goal and combine the research efforts of over 70 European universities, public research