Ovine pulmonary adenocarcinoma be predisposed to OPA. Most affected sheep show signs at 2 to 4 years of age. OPA is not a notifiable disease, and therefore it is difficult to assess its prevalence. OPA was first described in the UK in 1888, and described in detail in South Africa in 1891. The disease was initially known as "jaagsiekte" , a word derived from Afrikaans, meaning "chasing sickness," so called because animals are in respiratory distress as if they are out of breath from being chased. It has also been known as sheep pulmonary adenomatosis and ovine pulmonary carcinoma. OPA has been used
King Animal would be released on November 13, 2012. Explaining the title "King Animal", Cornell declared that it relates to how the band "were a big fish in a small pond, and we sort of graduated. There was a sense of us feeling like it was us four against the world. We clearly had that from the very beginning. In some weird way after all this time, we persevered. The album kind of stands out as a symbol and an indication of that." Thayil reported that some songs sound "similar in a sense to "Down on the Upside"" and that the album