Dermal fibroblast ECM which organizes the stratified squamous epithelial cells of the epidermis into a unified tissue. Furthermore, dermal fibroblasts create long fibrous bands of connective tissue which anchor the skin to the fascia of the body. Therefore, without dermal fibroblasts, the largest and heaviest organ would not tightly adhere to body's frame. Since dermal fibroblasts play a critical role in wound healing, researchers are attempting to generate mature dermal fibroblasts to repair second and third degree burns. When the body sustains a third degree burn, the skin's dermal layer is completely destroyed by heat (and the all fibroblast cells within the
What Difference Does It Make? and the covers featuring Morrissey are now very rare and collectible. "What Difference Does It Make?" was released without an accompanying music video. Speaking to Tony Fletcher on "The Tube" in 1984, Morrissey remarked that he felt that the video market was something that was going to "die very quickly", and that he wanted to "herald the death" of it. What Difference Does It Make? "What Difference Does It Make?" is a song by the English rock band the Smiths, written by singer Morrissey and guitarist Johnny Marr. It was the band's third single and is featured on their debut