Dermal fibroblast Dermal fibroblast Dermal fibroblasts are cells within the dermis layer of skin which are responsible for generating connective tissue and allowing the skin to recover from injury. Using organelles (particularly the rough endoplasmic reticulum), dermal fibroblasts generate and maintain the connective tissue which unites separate cell layers. Furthermore, these dermal fibroblasts produce the protein molecules including laminin and fibronectin which comprise the extracellular matrix. By creating the extracellular matrix between the dermis and epidermis, fibroblasts allow the epithelial cells of the epidermis to affix the matrix, thereby allowing the epidermal cells to effectively join together to form the top layer
What Kate Does week." VanDerWerff of the "LA Times", Ryan of the "Chicago Tribune", Sepinwall of "The Star-Ledger", Jensen of "Entertainment Weekly" and Mark Medley of the "National Post" also found the episode to contain humorous lines. This episode was watched by 11 million American viewers and 1.57 million Canadian viewers. What Kate Does "What Kate Does" is the 106th television episode of the American Broadcasting Company's "Lost" and third episode of the sixth season. It was written by executive producers Edward Kitsis and Adam Horowitz and directed in September 2009 by Paul Edwards. "What Kate Does" was first aired February 9, 2010,