Dermal fibroblast ECM which organizes the stratified squamous epithelial cells of the epidermis into a unified tissue. Furthermore, dermal fibroblasts create long fibrous bands of connective tissue which anchor the skin to the fascia of the body. Therefore, without dermal fibroblasts, the largest and heaviest organ would not tightly adhere to body's frame. Since dermal fibroblasts play a critical role in wound healing, researchers are attempting to generate mature dermal fibroblasts to repair second and third degree burns. When the body sustains a third degree burn, the skin's dermal layer is completely destroyed by heat (and the all fibroblast cells within the
What Kate Does the death of his love Juliet Burke (Elizabeth Mitchell) just hours earlier. In flash sideways to September 22, 2004, Kate assists a pregnant Claire Littleton (Emilie de Ravin) while on the run as a fugitive. The title alludes to the second season episode "What Kate Did". "What Kate Does" was watched by eleven million Americans and received mixed reviews by audiences and critics alike. In flash sideways, Kate Austen (Evangeline Lilly) flees LAX in a taxicab she has hijacked, in which a pregnant Claire Littleton (Emilie de Ravin) is a passenger. The cab driver (David H. Lawrence XVII) bails and