Dermal fibroblast altering their actin gene expression (which is silenced in dermal fibroblasts). When dermal fibroblasts express actin, the cells can slowly contract. This contraction plays a critical role in wound healing and fibrosis. By pulling tissues closed differentiated myofibroblasts, seal the skin after an injury (thereby, preventing infection but inducing scar formation. Myofibroblasts can also be derived from non-fibroblast sources. Based on evidence of α-SMA expression from lung injuries, myofibroblasts can "arise de novo" directly from mesenchymal stem cells. Unlike other fibroblast cell types, dermal fibroblasts are far less likely to change into other cell types. For example, when a dermal
The Description of the Human Body soul. A sick or injured body does not do what we want or moves in ways we do not want. He believed the death of the body stopped it from being fit to bring about movement. This did not necessarily happen because the soul left the body. René Descartes believed the body could exist through mechanical means alone. This included digestion, blood circulation, muscle movement and some brain function. He felt we all know what the human body is like because animals have similar bodies and we have all seen them opened up. He saw the body as a machine.