Dermal fibroblast ECM which organizes the stratified squamous epithelial cells of the epidermis into a unified tissue. Furthermore, dermal fibroblasts create long fibrous bands of connective tissue which anchor the skin to the fascia of the body. Therefore, without dermal fibroblasts, the largest and heaviest organ would not tightly adhere to body's frame. Since dermal fibroblasts play a critical role in wound healing, researchers are attempting to generate mature dermal fibroblasts to repair second and third degree burns. When the body sustains a third degree burn, the skin's dermal layer is completely destroyed by heat (and the all fibroblast cells within the
What Kate Does week." VanDerWerff of the "LA Times", Ryan of the "Chicago Tribune", Sepinwall of "The Star-Ledger", Jensen of "Entertainment Weekly" and Mark Medley of the "National Post" also found the episode to contain humorous lines. This episode was watched by 11 million American viewers and 1.57 million Canadian viewers. What Kate Does "What Kate Does" is the 106th television episode of the American Broadcasting Company's "Lost" and third episode of the sixth season. It was written by executive producers Edward Kitsis and Adam Horowitz and directed in September 2009 by Paul Edwards. "What Kate Does" was first aired February 9, 2010,