Focal dermal hypoplasia Focal dermal hypoplasia Focal dermal hypoplasia (also known as "Goltz syndrome") is a form of ectodermal dysplasia. It is a multisystem disorder characterized primarily by skin manifestations to the atrophic and hypoplastic areas of skin which are present at birth. These defects manifest as yellow-pink bumps on the skin and pigmentation changes. The disorder is also associated with shortness of stature and some evidence suggests that it can cause epilepsy. Focal dermal hypoplasia has been associated with PORCN gene mutations on the X chromosome. 90% of the individuals who are affected with the syndrome are female: the commonly accepted, though
Relate Relate Relate is a charity providing relationship support throughout the United Kingdom. Services include counselling for couples, families, young people and individuals, sex therapy, mediation and training courses. It was founded in 1938 as the National Marriage Guidance Council, after a clergyman, Herbert Gray (1868-1956), noted that the divorce rate was increasing. A co-founder of the Council was the Methodist David Mace (1907-1990). Another co-founder was eugenicist Dr Edward Fyfe Griffith. Relate adopted its current name on Valentine's Day 1988. In the 1990s, Relate's public profile increased after Princess Diana became its patron in 1989. Today, Relate sees over 150,000