Seed when castor beans have been ingested by animals. In addition, seeds containing amygdalin—apple, apricot, bitter almond, peach, plum, cherry, quince, and others—when consumed in sufficient amounts, may cause cyanide poisoning. Other seeds that contain poisons include annona, cotton, custard apple, datura, uncooked durian, golden chain, horse-chestnut, larkspur, locoweed, lychee, nectarine, rambutan, rosary pea, sour sop, sugar apple, wisteria, and yew. The seeds of the strychnine tree are also poisonous, containing the poison strychnine. The seeds of many legumes, including the common bean ("Phaseolus vulgaris"), contain proteins called lectins which can cause gastric distress if the beans are eaten without cooking.
Apple cultivars brought as seed from Europe were spread along Native American trade routes, as well as being cultivated on colonial farms. An 1845 United States apples nursery catalogue sold 350 of the "best" cultivars, showing the proliferation of new North American cultivars by the early 19th century. In the 20th century, irrigation projects in Eastern Washington began and allowed the development of the multibillion-dollar fruit industry, of which the apple is the leading product. Until the 20th century, farmers stored apples in frostproof cellars during the winter for their own use or for sale. Improved transportation of fresh apples by