Seed when castor beans have been ingested by animals. In addition, seeds containing amygdalin—apple, apricot, bitter almond, peach, plum, cherry, quince, and others—when consumed in sufficient amounts, may cause cyanide poisoning. Other seeds that contain poisons include annona, cotton, custard apple, datura, uncooked durian, golden chain, horse-chestnut, larkspur, locoweed, lychee, nectarine, rambutan, rosary pea, sour sop, sugar apple, wisteria, and yew. The seeds of the strychnine tree are also poisonous, containing the poison strychnine. The seeds of many legumes, including the common bean ("Phaseolus vulgaris"), contain proteins called lectins which can cause gastric distress if the beans are eaten without cooking.
Substance theory which "we can understand nothing else than an entity which "is" in such a way that it need no other entity in order to "be"." Therefore, only God is a substance as "Ens perfectissimus" (most perfect being). Heidegger showed the inextricable relationship between the concept of substance and of subject, which explains why, instead of talking about "man" or "humankind", he speaks about the "Dasein", which is not a simple subject, nor a substance. Alfred North Whitehead has argued that the concept of substance has only a limited applicability in everyday life and that metaphysics should rely upon the concept