Dermal fibroblast altering their actin gene expression (which is silenced in dermal fibroblasts). When dermal fibroblasts express actin, the cells can slowly contract. This contraction plays a critical role in wound healing and fibrosis. By pulling tissues closed differentiated myofibroblasts, seal the skin after an injury (thereby, preventing infection but inducing scar formation. Myofibroblasts can also be derived from non-fibroblast sources. Based on evidence of α-SMA expression from lung injuries, myofibroblasts can "arise de novo" directly from mesenchymal stem cells. Unlike other fibroblast cell types, dermal fibroblasts are far less likely to change into other cell types. For example, when a dermal
Does exactly what it says on the tin began a similar copycat advertising campaign in Ireland stating that its product "does exactly what it says on the tube". The phrase is a registered trademark of the Sherwin-Williams Company, the owner of Ronseal, across the European Community for products including paints, varnishes, and wood preservatives (E3085826). In 2007, a song titled "What It Says on the Tin" was released by the British singer Katie Melua. Although the song is about relationships, the phrase has a similar meaning. Does exactly what it says on the tin "It does exactly what it says on the tin" was originally an advertising slogan