Dermal fibroblast altering their actin gene expression (which is silenced in dermal fibroblasts). When dermal fibroblasts express actin, the cells can slowly contract. This contraction plays a critical role in wound healing and fibrosis. By pulling tissues closed differentiated myofibroblasts, seal the skin after an injury (thereby, preventing infection but inducing scar formation. Myofibroblasts can also be derived from non-fibroblast sources. Based on evidence of α-SMA expression from lung injuries, myofibroblasts can "arise de novo" directly from mesenchymal stem cells. Unlike other fibroblast cell types, dermal fibroblasts are far less likely to change into other cell types. For example, when a dermal
What She Does Best other singles charted far outside the Top 40. "How Many Hearts" was the last single Anderson released, and it peaked at No. 69 on the country charts in 1989. The album's cover shows Anderson leaning on a fancy sports car, wearing a classic 1980s outfit. What She Does Best What She Does Best is a studio album by country singer Lynn Anderson, released in 1988. It was her only album with Mercury records. Notable due to featuring her last charting single, "What She Does Best" did not chart and was commercially unsuccessful. It would be her last album for four