Head and neck anatomy may be important in the development of the BBB. Astrocytes may also be responsible for transporting ions (electrolytes) from the brain to the blood. Blood from the brain and neck flows from: (1) within the cranium via the internal jugular veins, a continuation of the sigmoid sinuses. The right and left external jugular veins drain from the parotid glands, facial muscles, scalp into the subclavian veins. The right and left vertebral veins drain the vertebrae and muscles into the right subclavian vein and into the superior vena cava, into the right atrium of the heart. The lymphatic system drains the
Hepatic veins ultimately from numerous central veins of the liver lobules. None of the hepatic veins have valves. The hepatic veins are divided into an upper and a lower group. The upper three drain the central veins from the right, middle, and left regions of the liver and are larger than the lower group of veins. The lower group of from six to twenty smaller hepatic veins come from the right lobe and the caudate lobe, are in contact with the hepatic tissue, and are valveless. All the veins empty into the inferior vena cava at the back of the liver. Budd–Chiari