Body piercing is frequently done in the form of a ladder. Modern body piercing practices also include dermal anchoring or dermal piercing, which combines piercing and implantation to create a single point of opening in the body (whereas pocketing creates two) to permit one end of the jewellery to show above the surface of the skin. While this technique can be performed almost anywhere on the body, as of 2007 it was popularly done between the eyes, on the chest, or on the finger, to simulate a ring. The practice of body piercing is subject to trends and fashions. Belly button and
Dermal equivalent Dermal equivalent The dermal equivalent is an in vitro model of the dermal layer of skin. It is constructed by seeding dermal fibroblasts into a collagen gel. This gel may then be allowed to contract as a model of wound contraction. This collagen gel contraction assay may be used to screen for treatments which promote or inhibit contraction and thus affect the development of a scar. Other cell types may be incorporated into the dermal equivalent to increase the complexity of the model. For example, keratinocytes may be seeded on the surface to create a skin equivalent, or macrophages may