Dermal fibroblast fibroblast and a corneal fibroblasts are placed in the same concentrations of fibroblast growth factor, dermal fibroblast will not differentiate or change. As noted by Dr. J. Lewis and Dr. A. Johnson authors of "Microbiology of the Cell", "fibroblasts from the skin are different" and behave differently from other fibroblast cells to identical chemical stimuli. Furthermore, dermal fibroblasts are less likely to replicate in either "in vivo" and "in vitro" environments than are other fibroblast types. Dermal fibroblasts require far higher concentrations of fibroblast growth factor (FGF) in order to undergo cell replication. Dermal fibroblasts are responsible for creating the
The purpose of a system is what it does be balanced by a more straightforwardly descriptive view. The term is used in many fields including biology and management. The purpose of a system is what it does The purpose of a system is what it does (POSIWID) is a systems thinking heuristic coined by Stafford Beer. Stafford Beer coined the term POSIWID and used it many times in public addresses. In his address to the University of Valladolid, Spain, in October 2001, he said "According to the cybernetician, the purpose of a system is what it does. This is a basic dictum. It stands for bald fact, which makes