Focal dermal hypoplasia Focal dermal hypoplasia Focal dermal hypoplasia (also known as "Goltz syndrome") is a form of ectodermal dysplasia. It is a multisystem disorder characterized primarily by skin manifestations to the atrophic and hypoplastic areas of skin which are present at birth. These defects manifest as yellow-pink bumps on the skin and pigmentation changes. The disorder is also associated with shortness of stature and some evidence suggests that it can cause epilepsy. Focal dermal hypoplasia has been associated with PORCN gene mutations on the X chromosome. 90% of the individuals who are affected with the syndrome are female: the commonly accepted, though
Composition of the human body g in men, ~2.3 g in women Of the 94 naturally occurring chemical elements, 60 are listed in the table above. Of the remaining 34, it is not known how many occur in the human body. Most of the elements needed for life are relatively common in the Earth's crust. Aluminium, the third most common element in the Earth's crust (after oxygen and silicon), serves no function in living cells, but is harmful in large amounts. Transferrins can bind aluminium. The composition of the human body is expressed in terms of chemicals: The composition of the human body can be