Dermal fibroblast altering their actin gene expression (which is silenced in dermal fibroblasts). When dermal fibroblasts express actin, the cells can slowly contract. This contraction plays a critical role in wound healing and fibrosis. By pulling tissues closed differentiated myofibroblasts, seal the skin after an injury (thereby, preventing infection but inducing scar formation. Myofibroblasts can also be derived from non-fibroblast sources. Based on evidence of α-SMA expression from lung injuries, myofibroblasts can "arise de novo" directly from mesenchymal stem cells. Unlike other fibroblast cell types, dermal fibroblasts are far less likely to change into other cell types. For example, when a dermal
P.S.K. What Does It Mean? P.S.K. What Does It Mean? "P.S.K. What Does It Mean?" (also written as "P.S.K. (What Does It Mean?)") is a song released in 1985 by Philadelphia rapper Schoolly D on his independent label Schoolly D Records. P.S.K. is the abbreviation for Park Side Killas, a street gang with which Schoolly D was affiliated. The highly influential song is considered the first hardcore rap song and features incidents of graphic sex, gunplay, drug references and one of the first uses of the word "nigga" in a rap song (earlier uses include "Scoopy Rap" and "Family Rap" in 1979, and "New York