Focal dermal hypoplasia popular during the second half of the 20th century. Focal dermal hypoplasia Focal dermal hypoplasia (also known as "Goltz syndrome") is a form of ectodermal dysplasia. It is a multisystem disorder characterized primarily by skin manifestations to the atrophic and hypoplastic areas of skin which are present at birth. These defects manifest as yellow-pink bumps on the skin and pigmentation changes. The disorder is also associated with shortness of stature and some evidence suggests that it can cause epilepsy. Focal dermal hypoplasia has been associated with PORCN gene mutations on the X chromosome. 90% of the individuals who are affected
Human body and about 23 litres of fluid inside cells. The content, acidity and composition of the water inside and outside cells is carefully maintained. The main electrolytes in body water outside cells are sodium and chloride, whereas within cells it is potassium and other phosphates. The body contains trillions of cells, the fundamental unit of life. At maturity, there are roughly 30–37 trillion cells in the body, an estimate arrived at by totalling the cell numbers of all the organs of the body and cell types. The body is also host to about the same number of non-human cells as well