Dermal fibroblast altering their actin gene expression (which is silenced in dermal fibroblasts). When dermal fibroblasts express actin, the cells can slowly contract. This contraction plays a critical role in wound healing and fibrosis. By pulling tissues closed differentiated myofibroblasts, seal the skin after an injury (thereby, preventing infection but inducing scar formation. Myofibroblasts can also be derived from non-fibroblast sources. Based on evidence of α-SMA expression from lung injuries, myofibroblasts can "arise de novo" directly from mesenchymal stem cells. Unlike other fibroblast cell types, dermal fibroblasts are far less likely to change into other cell types. For example, when a dermal
The Human Body (TV series) The Human Body (TV series) The Human Body is a seven-part documentary series, first shown on 20 May 1998 on BBC One and presented by medical scientist Robert Winston. A co-production between the BBC and The Learning Channel, the series looks at the mechanics and emotions of the human body from birth to death. The series was nominated for numerous awards, winning several, including three BAFTA awards, four RTS awards and a Peabody Award. Described as the BBC's "first major TV series on human biology", it took over two years to make and aimed to be the definitive set of