Dermal fibroblast wound site perish. Without fibroblasts, the wound site cannot regenerate extracellular matrix and epidermis skin cells cannot proliferate over the wound site. Therefore, without dermal fibroblasts the skin cannot properly recover from injury. Yet, by differentiating mesenchymal stem cells from other regions of the body and injecting them into the wound site, scientists can restore dermal fibroblasts to burned regions of the body. By restoring fibroblasts to the burned regions, the body can restore the ECM within the wound site and recover from the injury. As noted "The injured dermis is also repaired by the recruitment and proliferation of fibroblasts
What Kate Does week." VanDerWerff of the "LA Times", Ryan of the "Chicago Tribune", Sepinwall of "The Star-Ledger", Jensen of "Entertainment Weekly" and Mark Medley of the "National Post" also found the episode to contain humorous lines. This episode was watched by 11 million American viewers and 1.57 million Canadian viewers. What Kate Does "What Kate Does" is the 106th television episode of the American Broadcasting Company's "Lost" and third episode of the sixth season. It was written by executive producers Edward Kitsis and Adam Horowitz and directed in September 2009 by Paul Edwards. "What Kate Does" was first aired February 9, 2010,