Synderesis their opposites as evils to be avoided. Synderesis is the capacity not only to apprehend the first principles, but also to judge every step of the practical discourse in the light of those principles. But, as an intellectual disposition concerned with knowledge of the first principles of action, synderesis provides only the universal premise of the practical syllogism. Every human "action", however, is singular, contingent and takes place in particular circumstances. To complete the practical discourse and reach a conclusion regarding what has to be done "hic et nunc" [here and now] and what means are to be used, other
Ephraim Chambers with John Martyn to translate the "History and Memoirs of the Royal Academy of Sciences at Paris" (1742). Chambers' epitaph was published in both the original Latin and in English in the "Gentleman's Magazine", volume 10, as follows (translation is the original): <poem> Multis pervulgatus paucis notus Qui vitam inter lucem et umbram Nec eruditus nec idiota Literis deditus transegit, sed ut homo Qui humani nihil a se alienum putat Vita simul et laboribus functus Hic requiescere voluit EPHRAIM CHAMBERS. </poem> In English thus: <poem> Heard of by many, Known to few, Who led a Life between Fame and Obscurity