Dermal fibroblast altering their actin gene expression (which is silenced in dermal fibroblasts). When dermal fibroblasts express actin, the cells can slowly contract. This contraction plays a critical role in wound healing and fibrosis. By pulling tissues closed differentiated myofibroblasts, seal the skin after an injury (thereby, preventing infection but inducing scar formation. Myofibroblasts can also be derived from non-fibroblast sources. Based on evidence of α-SMA expression from lung injuries, myofibroblasts can "arise de novo" directly from mesenchymal stem cells. Unlike other fibroblast cell types, dermal fibroblasts are far less likely to change into other cell types. For example, when a dermal
Traditional Chinese medicines derived from the human body "Three Corpses; demonic spirits believed to live in the human body and hasten death" and "gǔdú" 蠱毒 "gu poisoning"; a poison produced by venomous insects; cast a black magic spirit possession over someone". The first "Bencao gangmu" prescription for human nails is not from Chinese medical texts but from Daoist rituals for expelling what (Cooper & Sivin (1973: 220) describe as the "Three Corpse-Worms 三尸, the chief of the "inner gods" who are to the individual microcosm what the celestial bureaucracy is to the cosmos." Prescription 52.6.1, the 斬三尸法 "Method of Beheading the Three Corpses", involves supernaturally cutting the nails