Seed when castor beans have been ingested by animals. In addition, seeds containing amygdalin—apple, apricot, bitter almond, peach, plum, cherry, quince, and others—when consumed in sufficient amounts, may cause cyanide poisoning. Other seeds that contain poisons include annona, cotton, custard apple, datura, uncooked durian, golden chain, horse-chestnut, larkspur, locoweed, lychee, nectarine, rambutan, rosary pea, sour sop, sugar apple, wisteria, and yew. The seeds of the strychnine tree are also poisonous, containing the poison strychnine. The seeds of many legumes, including the common bean ("Phaseolus vulgaris"), contain proteins called lectins which can cause gastric distress if the beans are eaten without cooking.
Carissa though some species have fruity flavours with overtones of strawberry or apple. They are rich in Vitamin C, calcium, magnesium and phosphorus. The fruit of "C. macrocarpa" are especially relished and eaten raw or used to make jelly. Various birds eat "Carissa" fruit and distribute the seed. If eaten before fully ripe, a bitter, poisonous latex is released from the skin. Other than the ripe fruit, the plant is poisonous, much like the related and dangerously poisonous genus "Acokanthera". "Carissa carandas" is grown in several Asiatic countries for its fruit, which is variously used in cooking and in folk medicine