Dermal fibroblast wound site perish. Without fibroblasts, the wound site cannot regenerate extracellular matrix and epidermis skin cells cannot proliferate over the wound site. Therefore, without dermal fibroblasts the skin cannot properly recover from injury. Yet, by differentiating mesenchymal stem cells from other regions of the body and injecting them into the wound site, scientists can restore dermal fibroblasts to burned regions of the body. By restoring fibroblasts to the burned regions, the body can restore the ECM within the wound site and recover from the injury. As noted "The injured dermis is also repaired by the recruitment and proliferation of fibroblasts
What Kate Does the death of his love Juliet Burke (Elizabeth Mitchell) just hours earlier. In flash sideways to September 22, 2004, Kate assists a pregnant Claire Littleton (Emilie de Ravin) while on the run as a fugitive. The title alludes to the second season episode "What Kate Did". "What Kate Does" was watched by eleven million Americans and received mixed reviews by audiences and critics alike. In flash sideways, Kate Austen (Evangeline Lilly) flees LAX in a taxicab she has hijacked, in which a pregnant Claire Littleton (Emilie de Ravin) is a passenger. The cab driver (David H. Lawrence XVII) bails and