Dermal fibroblast altering their actin gene expression (which is silenced in dermal fibroblasts). When dermal fibroblasts express actin, the cells can slowly contract. This contraction plays a critical role in wound healing and fibrosis. By pulling tissues closed differentiated myofibroblasts, seal the skin after an injury (thereby, preventing infection but inducing scar formation. Myofibroblasts can also be derived from non-fibroblast sources. Based on evidence of α-SMA expression from lung injuries, myofibroblasts can "arise de novo" directly from mesenchymal stem cells. Unlike other fibroblast cell types, dermal fibroblasts are far less likely to change into other cell types. For example, when a dermal
What Difference Does It Make? and the covers featuring Morrissey are now very rare and collectible. "What Difference Does It Make?" was released without an accompanying music video. Speaking to Tony Fletcher on "The Tube" in 1984, Morrissey remarked that he felt that the video market was something that was going to "die very quickly", and that he wanted to "herald the death" of it. What Difference Does It Make? "What Difference Does It Make?" is a song by the English rock band the Smiths, written by singer Morrissey and guitarist Johnny Marr. It was the band's third single and is featured on their debut