Focal dermal hypoplasia popular during the second half of the 20th century. Focal dermal hypoplasia Focal dermal hypoplasia (also known as "Goltz syndrome") is a form of ectodermal dysplasia. It is a multisystem disorder characterized primarily by skin manifestations to the atrophic and hypoplastic areas of skin which are present at birth. These defects manifest as yellow-pink bumps on the skin and pigmentation changes. The disorder is also associated with shortness of stature and some evidence suggests that it can cause epilepsy. Focal dermal hypoplasia has been associated with PORCN gene mutations on the X chromosome. 90% of the individuals who are affected
Traditional Chinese medicines derived from the human body "Three Corpses; demonic spirits believed to live in the human body and hasten death" and "gǔdú" 蠱毒 "gu poisoning"; a poison produced by venomous insects; cast a black magic spirit possession over someone". The first "Bencao gangmu" prescription for human nails is not from Chinese medical texts but from Daoist rituals for expelling what (Cooper & Sivin (1973: 220) describe as the "Three Corpse-Worms 三尸, the chief of the "inner gods" who are to the individual microcosm what the celestial bureaucracy is to the cosmos." Prescription 52.6.1, the 斬三尸法 "Method of Beheading the Three Corpses", involves supernaturally cutting the nails