Dermal fibroblast wound site perish. Without fibroblasts, the wound site cannot regenerate extracellular matrix and epidermis skin cells cannot proliferate over the wound site. Therefore, without dermal fibroblasts the skin cannot properly recover from injury. Yet, by differentiating mesenchymal stem cells from other regions of the body and injecting them into the wound site, scientists can restore dermal fibroblasts to burned regions of the body. By restoring fibroblasts to the burned regions, the body can restore the ECM within the wound site and recover from the injury. As noted "The injured dermis is also repaired by the recruitment and proliferation of fibroblasts
Traditional Chinese medicines derived from the human body were successfully making quasi-empirical preparations of active substances with androgens and estrogens, a technique that modern biochemists did not develop until the early 20th century. The physician William C. Cooper and the sinologist Nathan Sivin (1973) chose what the Chinese call "rényào" 人藥 "human drugs" as a pilot experiment sample for pharmacologically analyzing the efficacy of drugs used in TCM. In contrast to many traditional Chinese plant, animal, and mineral pharmaceuticals with uncertain active constituents, the chemical composition of the human body and parts is well known, and "their therapeutic effectiveness, or lack of it, can be objectively, if approximately,