Focal dermal hypoplasia popular during the second half of the 20th century. Focal dermal hypoplasia Focal dermal hypoplasia (also known as "Goltz syndrome") is a form of ectodermal dysplasia. It is a multisystem disorder characterized primarily by skin manifestations to the atrophic and hypoplastic areas of skin which are present at birth. These defects manifest as yellow-pink bumps on the skin and pigmentation changes. The disorder is also associated with shortness of stature and some evidence suggests that it can cause epilepsy. Focal dermal hypoplasia has been associated with PORCN gene mutations on the X chromosome. 90% of the individuals who are affected
Does exactly what it says on the tin began a similar copycat advertising campaign in Ireland stating that its product "does exactly what it says on the tube". The phrase is a registered trademark of the Sherwin-Williams Company, the owner of Ronseal, across the European Community for products including paints, varnishes, and wood preservatives (E3085826). In 2007, a song titled "What It Says on the Tin" was released by the British singer Katie Melua. Although the song is about relationships, the phrase has a similar meaning. Does exactly what it says on the tin "It does exactly what it says on the tin" was originally an advertising slogan