Systole heart beats—is cued by messages from the brain, reflecting the brain's responses to conditions of the body, such as pain, emotional stress, level of activity, and to ambient conditions including external temperature, time of day, etc. Electrical systole opens voltage-gated sodium, potassium and calcium channels in cells of myocardium tissue. Subsequently, a rise in intracellular calcium triggers the interaction of actin and myosin in the presence of ATP which generates mechanical force in the cells in the form of muscular contraction, or mechanical systole. The contractions generate intra-ventricular pressure, which is increased until it exceeds the external, residual pressures in
Errors of the Human Body Errors of the Human Body Errors of the Human Body is a 2012 psychological thriller directed by Eron Sheean and starring Michael Eklund. Dr. Geoff Burton (Eklund), a brilliant genetics researcher, is invited to a lab in Dresden, only to discover a lethal virus is being created, which he may have unintentionally caused and be its first victim. This mystery is set against Dr. Burton trying to find redemption and peace from a past haunted by the death of his infant son. While showing a short film at Berlinale in 2006, Sheean met a scientist from the Max Planck Institute