Vogt–Koyanagi–Harada disease at the University of Tokyo, in 1911. It was the much later article, published in 1929, that definitively associated Koyanagi with the disease. Harada's 1926 paper is recognized for its comprehensive description of what is now known as Vogt–Koyanagi–Harada disease. Vogt–Koyanagi–Harada disease Vogt–Koyanagi–Harada disease (VKH), also known as Vogt–Koyanagi–Harada syndrome, uveomeningitis syndrome and uveomeningoencephalitic syndrome, is a multisystem disease of presumed autoimmune cause, that affects pigmented tissues, which have melanin. The most significant manifestation is bilateral, diffuse uveitis, which affects the eye. VKH may variably also involve the inner ear with effects on hearing, the skin, and the meninges of
Motor neuron disease Motor neuron disease Motor neuron diseases (MNDs) are a group of neurodegenerative disorders that selectively affect motor neurons, the cells which control voluntary muscles of the body. Commonly, the following disorders are counted among motor neuron diseases: The term “motor neuron disease” sometimes refers to ALS, but in this article, the term refers to a group of diseases listed above, which includes ALS. Motor neuron diseases affect both children and adults. While each motor neuron disease affects patients differently, they all cause movement-related symptoms, mainly muscle weakness. Most diseases seem to occur randomly without known causes, but some forms are