Pathophysiology of heart failure caused by dysfunction or destruction of cardiac myocytes or their molecular components. In congenital diseases such as Duchenne muscular dystrophy, the molecular structure of individual myocytes is affected. Myocytes and their components can be damaged by inflammation (such as in myocarditis) or by infiltration (such as in amyloidosis). Toxins and pharmacological agents (such as ethanol, cocaine, doxorubicin, and amphetamines) cause intracellular damage and oxidative stress. The most common mechanism of damage is ischemia causing infarction and scar formation. After myocardial infarction, dead myocytes are replaced by scar tissue, deleteriously affecting the function of the myocardium. On echocardiogram, this is manifest
101 Things Removed from the Human Body 101 Things Removed from the Human Body 101 Things Removed from the Human Body and 101 More Things Removed from the Human Body is a British "shockumentary" series directed by Eric Schotz, which is narrated by Mitch Lewis. The program features tales of foreign objects that have been removed from human bodies in the form of a countdown from 101 to 1. Items included are javelins, a boat anchor, a bicycle pump, a bag of nails, an ice pick, and a human body. The documentary series was first broadcast on Sky One in October 2003. When the show was re-broadcast