Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Sociopolitical issues of anatomy in America in the 19th century set up to teach people the natural and moral sciences of the human body, anatomy museums gradually declined in status with the progress of medical science and education. In postbellum America, the division between high and low medicine increased. The focus of public scientific education turned toward the structures and functions of plants, animals, and cells, and this was done through politically and socially approved public school curriculums and sanitary fairs. These other avenues not only appeared more legitimate, but also reduced the uniqueness of anatomy museums. Anatomy museums' popularity also suffered with the establishment of nonprofit art and natural