Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Crown (anatomy) crown and occiput, is sometimes called the pileum. A bird with a crest covering the pileum may be described as "pileated", e.g. the pileated woodpecker. In whale anatomy the crown is the bulge on the head through which the blow-holes emerge. Crown (anatomy) The crown is the top of the head, or the whole head. Crown can mean the top of the head and it can also mean the whole head. In the study of human anatomy the terms "Calvaria, "skullcap", "skull cap", or the "roof of the cranial cavity" are used for the top part of the head. In