Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
The Human Body (TV series) The Human Body (TV series) The Human Body is a seven-part documentary series, first shown on 20 May 1998 on BBC One and presented by medical scientist Robert Winston. A co-production between the BBC and The Learning Channel, the series looks at the mechanics and emotions of the human body from birth to death. The series was nominated for numerous awards, winning several, including three BAFTA awards, four RTS awards and a Peabody Award. Described as the BBC's "first major TV series on human biology", it took over two years to make and aimed to be the definitive set of