Otic vesicle constricts to form the canalis reuniens. The central part of the otic vesicle represents the membranous vestibule, and is subdivided by a constriction into a smaller ventral part, the saccule, and a larger dorsal and posterior part, the utricle. The dorsal component of the inner ear also consists of what will become the semicircular canals. The utricle and saccule communicate with each other by means of a Y-shaped canal. The FGF, Bmp, Wnt and Pax genes are likely to be involved in otic induction. FGF and BMP signals help control patterning in the early otic vesicle. Fgf3 and Fgf10 are
History of anatomy in the 19th century horror of being the subject of dissection. The criminal temptations ultimately led to the 1827–1828 West Port murders in Edinburgh, UK, where likely candidates were killed and sold for cash. The murders led to the passing of the Anatomy Act 1832 which finally provided for an adequate and legitimate supply of corpses. History of anatomy in the 19th century The history of anatomy in the 19th century saw anatomists largely finalise and systematise the descriptive human anatomy of the previous century. The discipline also progressed to establish growing sources of knowledge in histology and developmental biology, not only of humans