Otic vesicle Otic vesicle Otic vesicle, or auditory vesicle, consists of either of the two sac-like invaginations formed and subsequently closed off during embryonic development. It is part of the neural ectoderm, which will develop into the membranous labyrinth of the inner ear. This labyrinth is a continuous epithelium, giving rise to the vestibular system and auditory components of the inner ear. During the earlier stages of embryogenesis, the otic placode invaginates to produce the otic cup. Thereafter, the otic cup closes off, creating the otic vesicle. Once formed, the otic vesicle will reside next to the neural tube medially, and on
Human body writing the influential book "De humani corporis fabrica". Anatomy advanced further with the invention of the microscope and the study of the cellular structure of tissues and organs. Modern anatomy uses techniques such as magnetic resonance imaging, computed tomography, fluoroscopy and ultrasound imaging to study the body in unprecedented detail. The study of human physiology began with Hippocrates in Ancient Greece, around 420 BC, and with Aristotle (384–322 BC) who applied critical thinking and emphasis on the relationship between structure and function. Galen (c. 126–199) was the first to use experiments to probe the body's functions. The term physiology was