Otic vesicle constricts to form the canalis reuniens. The central part of the otic vesicle represents the membranous vestibule, and is subdivided by a constriction into a smaller ventral part, the saccule, and a larger dorsal and posterior part, the utricle. The dorsal component of the inner ear also consists of what will become the semicircular canals. The utricle and saccule communicate with each other by means of a Y-shaped canal. The FGF, Bmp, Wnt and Pax genes are likely to be involved in otic induction. FGF and BMP signals help control patterning in the early otic vesicle. Fgf3 and Fgf10 are
Human body temperature Human body temperature Normal human body temperature, also known as normothermia or euthermia, is the typical temperature range found in humans. The normal human body temperature range is typically stated as . Individual body temperature depends upon the age, exertion, infection, sex, and reproductive status of the subject, the time of day, the place in the body at which the measurement is made, and the subject's state of consciousness (waking, sleeping or sedated), activity level, and emotional state. It is typically maintained within this range by thermoregulation. Taking a person's temperature is an initial part of a full clinical examination.