Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Explorers of the Human Body new educational program, introducing the audience to the human body. Shin Dong-yup was chosen to be the lead MC, with the Super Junior members being regulars and co-MCs of the program. Ratings for the show became the highest of all three shows that aired in SBS's new "Good Sunday" lineup as the show is educational and entertaining to watch. It was also the first and currently the only variety show that included every member of Super Junior as regulars. Each episode has a main topic to explore regarding the human body. In the first episode, which involved the tongue and