Pathophysiology of heart failure caused by dysfunction or destruction of cardiac myocytes or their molecular components. In congenital diseases such as Duchenne muscular dystrophy, the molecular structure of individual myocytes is affected. Myocytes and their components can be damaged by inflammation (such as in myocarditis) or by infiltration (such as in amyloidosis). Toxins and pharmacological agents (such as ethanol, cocaine, doxorubicin, and amphetamines) cause intracellular damage and oxidative stress. The most common mechanism of damage is ischemia causing infarction and scar formation. After myocardial infarction, dead myocytes are replaced by scar tissue, deleteriously affecting the function of the myocardium. On echocardiogram, this is manifest
History of beliefs about the human body History of beliefs about the human body The human body has been subject of much debate. How people are defined, and what defined them – be it their anatomy or their energy or both – depends on culture and time. Culture not only defines how sex is perceived but also how gender is defined. Today gender, sex, and identity continue to be of much debate and change based on what place and people are being examined. The early modern idea of the body was a cultural ideal, an understanding and approach to how the body works and what place that