Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Development of the human body Development of the human body Human development is the process of growth to maturity. The process begins with fertilisation, where an egg released from the ovary of a female is penetrated by a sperm cell from a male. The egg then lodges in the uterus, where an embryo and later fetus develop until birth. Further growth and development continues after birth, and includes both physical and psychological development, influenced by genetic, hormonal, environmental and other factors. This continues throughout life, through childhood, and adolescence into adulthood. Development before birth, or prenatal development () is the process in which an embryo