Pathophysiology of heart failure caused by dysfunction or destruction of cardiac myocytes or their molecular components. In congenital diseases such as Duchenne muscular dystrophy, the molecular structure of individual myocytes is affected. Myocytes and their components can be damaged by inflammation (such as in myocarditis) or by infiltration (such as in amyloidosis). Toxins and pharmacological agents (such as ethanol, cocaine, doxorubicin, and amphetamines) cause intracellular damage and oxidative stress. The most common mechanism of damage is ischemia causing infarction and scar formation. After myocardial infarction, dead myocytes are replaced by scar tissue, deleteriously affecting the function of the myocardium. On echocardiogram, this is manifest
Catholic theology of the body communicate with him. The human body is the lower element of the human person. Through the body, man experiences his temporal existence. But Gregory also admired human beauty and the bodily abilities to dream, sleep and memorize. The body can be both a friend and enemy of a person, according to Gregory. The final goal is a unity of the soul with God, which is possible with Grace and the assistance of the Holy Spirit according to Gregory. Gregory of Nyssa (335-394) was a bishop who wrote, among others, about the creation of the human body. Unlike Irenaeus, Gregory states,