Systole heart beats—is cued by messages from the brain, reflecting the brain's responses to conditions of the body, such as pain, emotional stress, level of activity, and to ambient conditions including external temperature, time of day, etc. Electrical systole opens voltage-gated sodium, potassium and calcium channels in cells of myocardium tissue. Subsequently, a rise in intracellular calcium triggers the interaction of actin and myosin in the presence of ATP which generates mechanical force in the cells in the form of muscular contraction, or mechanical systole. The contractions generate intra-ventricular pressure, which is increased until it exceeds the external, residual pressures in
History of beliefs about the human body History of beliefs about the human body The human body has been subject of much debate. How people are defined, and what defined them – be it their anatomy or their energy or both – depends on culture and time. Culture not only defines how sex is perceived but also how gender is defined. Today gender, sex, and identity continue to be of much debate and change based on what place and people are being examined. The early modern idea of the body was a cultural ideal, an understanding and approach to how the body works and what place that