Otic vesicle constricts to form the canalis reuniens. The central part of the otic vesicle represents the membranous vestibule, and is subdivided by a constriction into a smaller ventral part, the saccule, and a larger dorsal and posterior part, the utricle. The dorsal component of the inner ear also consists of what will become the semicircular canals. The utricle and saccule communicate with each other by means of a Y-shaped canal. The FGF, Bmp, Wnt and Pax genes are likely to be involved in otic induction. FGF and BMP signals help control patterning in the early otic vesicle. Fgf3 and Fgf10 are
Limb (anatomy) feet are specialized for two-legged locomotion – most other mammals walk and run on all four limbs. Human arms are weaker, but very mobile allowing us to reach at a wide range of distances and angles, and end in specialized hands capable of grasping and fine manipulation of objects. Limb (anatomy) A limb (from the Old English "lim"), or extremity, is a jointed, or prehensile (as octopus arms or new world monkey tails), appendage of the human or other animal body. In the human body, the upper and lower limbs are commonly called the arms and the legs, respectively. Arms