Hibernating myocardium Hibernating myocardium In cardiology, hibernating myocardium is a state when some segments of the myocardium exhibit abnormalities of contractile function. These abnormalities can be visualised with echocardiography, cardiac magnetic resonance imaging (CMR), nuclear medicine (PET) or ventriculography. Echocardiography: A wall motion abnormality at rest which improves during a low-dose dobutamine stress test is classified as "hibernating myocardium". Low dose dobutamine stimulates contractile function and thus helps to predict functional recovery after revascularization. Cardiac magnetic resonance: The most frequently used MR contrast agents based on Gd-chelates accumulate in the extracellular space which is increased in scarred myocardium. This leads to a
Edmund Alexander Parkes Exercise on the Elimination of Nitrogen". He confirmed independently the observations of Adolf Eugen Fick and Johannes Wislicenus, against Justus Liebig's theory that muscular work implies the destruction of muscular tissue by oxidation. Parkes suggested that the elimination of urea is not dependent on the amount of muscular exercise, but on the consumption of nitrogenous food; and that muscular tissue does not consume itself as a fuel doing work. His experiments on the effects of alcohol on the human body (in which he was assisted by Cyprian Wollowicz) were in three papers (in 1870, 1872, and 1874), on the "Effects