Otic vesicle chick, invagination of the otic placode occurs passively due to the movements of the surrounding placode. The otic placode in zebrafish, on the other hand, occurs by cavitation; the ectodermal placode condenses and forms an ovoid ball directly below the embryo surface. Otic vesicle formation occurs later, during the 25-30 somite stage in mice. Otic vesicle Otic vesicle, or auditory vesicle, consists of either of the two sac-like invaginations formed and subsequently closed off during embryonic development. It is part of the neural ectoderm, which will develop into the membranous labyrinth of the inner ear. This labyrinth is a continuous
Human body writing the influential book "De humani corporis fabrica". Anatomy advanced further with the invention of the microscope and the study of the cellular structure of tissues and organs. Modern anatomy uses techniques such as magnetic resonance imaging, computed tomography, fluoroscopy and ultrasound imaging to study the body in unprecedented detail. The study of human physiology began with Hippocrates in Ancient Greece, around 420 BC, and with Aristotle (384–322 BC) who applied critical thinking and emphasis on the relationship between structure and function. Galen (c. 126–199) was the first to use experiments to probe the body's functions. The term physiology was