Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Human head Human head In human anatomy, the head is at the top of the human body. It supports the face and is maintained by the skull, which itself encloses the brain. The human head consists of a fleshy outer portion, which surrounds the bony skull. The brain is enclosed within the skull. The head rests on the neck, and the seven cervical vertebrae support it. The human head typically weighs between The face is the anterior part of the head, containing the eyes, nose, and mouth. On either side of the mouth, the cheeks provide a fleshy border to the oral