Otic vesicle constricts to form the canalis reuniens. The central part of the otic vesicle represents the membranous vestibule, and is subdivided by a constriction into a smaller ventral part, the saccule, and a larger dorsal and posterior part, the utricle. The dorsal component of the inner ear also consists of what will become the semicircular canals. The utricle and saccule communicate with each other by means of a Y-shaped canal. The FGF, Bmp, Wnt and Pax genes are likely to be involved in otic induction. FGF and BMP signals help control patterning in the early otic vesicle. Fgf3 and Fgf10 are
History of anatomy History of anatomy The history of anatomy extends from the earliest examinations of sacrificial victims to the sophisticated analyses of the body performed by modern scientists. The study of human anatomy can be traced back thousands of years, at least to the Egyptians, but the science of anatomy, as we know it today, did not develop until far later. The development of the study of anatomy gradually built upon concepts that were understood during the time of Galen and slowly became a part of the traditional medical curriculum. It has been characterized, over time, by a continually developing understanding of