Otic vesicle Otic vesicle Otic vesicle, or auditory vesicle, consists of either of the two sac-like invaginations formed and subsequently closed off during embryonic development. It is part of the neural ectoderm, which will develop into the membranous labyrinth of the inner ear. This labyrinth is a continuous epithelium, giving rise to the vestibular system and auditory components of the inner ear. During the earlier stages of embryogenesis, the otic placode invaginates to produce the otic cup. Thereafter, the otic cup closes off, creating the otic vesicle. Once formed, the otic vesicle will reside next to the neural tube medially, and on
History of anatomy in the 19th century History of anatomy in the 19th century The history of anatomy in the 19th century saw anatomists largely finalise and systematise the descriptive human anatomy of the previous century. The discipline also progressed to establish growing sources of knowledge in histology and developmental biology, not only of humans but also of animals. Samuel Thomas von Sömmerring originally published a clear, accurate and precise system in German (1791–1796), then in Latin (1794–1800). There was a second German edition in 1800–1801 and a further eight-volume edition (1841–1844) revised and with additional material by Th.L.W. Bischoff, Friedrich Gustav Jakob Henle, E.H. Huschke, Theile,