Systole heart beats—is cued by messages from the brain, reflecting the brain's responses to conditions of the body, such as pain, emotional stress, level of activity, and to ambient conditions including external temperature, time of day, etc. Electrical systole opens voltage-gated sodium, potassium and calcium channels in cells of myocardium tissue. Subsequently, a rise in intracellular calcium triggers the interaction of actin and myosin in the presence of ATP which generates mechanical force in the cells in the form of muscular contraction, or mechanical systole. The contractions generate intra-ventricular pressure, which is increased until it exceeds the external, residual pressures in
Human Tissue Act 2004 since most surgeons would be unwilling to confront families in such situations. The Act prohibits selling organs. In 2007 a man became the first person convicted under the Act for trying to sell his kidney online for £24,000 in order to pay off his gambling debts. The Act does not extend to Scotland; its counterpart there is the Human Tissue (Scotland) Act 2006. The following orders have been made under this section: Human Tissue Act 2004 The Human Tissue Act 2004 (c 30) is an act of the UK parliament applying to England, Northern Ireland and Wales. It consolidates previous