Pathophysiology of heart failure caused by dysfunction or destruction of cardiac myocytes or their molecular components. In congenital diseases such as Duchenne muscular dystrophy, the molecular structure of individual myocytes is affected. Myocytes and their components can be damaged by inflammation (such as in myocarditis) or by infiltration (such as in amyloidosis). Toxins and pharmacological agents (such as ethanol, cocaine, doxorubicin, and amphetamines) cause intracellular damage and oxidative stress. The most common mechanism of damage is ischemia causing infarction and scar formation. After myocardial infarction, dead myocytes are replaced by scar tissue, deleteriously affecting the function of the myocardium. On echocardiogram, this is manifest
History of beliefs about the human body as Traditional chinese medicine, or western, which follows the Greek traditions of science and is more closely related to modern science despite original anatomists and ideas of the body being just as unscientific as Chinese practices. In Western historical research, scholars began investigating the cultural history of the human body in detail in the 1980s. The movement is particularly associated with the historian of medicine Roy Porter, whose 1991 article 'History of the Body' was a seminal study. 1995 saw the foundation of the journal "Body and Society", by which time the field of the history of the body was