Systole heart beats—is cued by messages from the brain, reflecting the brain's responses to conditions of the body, such as pain, emotional stress, level of activity, and to ambient conditions including external temperature, time of day, etc. Electrical systole opens voltage-gated sodium, potassium and calcium channels in cells of myocardium tissue. Subsequently, a rise in intracellular calcium triggers the interaction of actin and myosin in the presence of ATP which generates mechanical force in the cells in the form of muscular contraction, or mechanical systole. The contractions generate intra-ventricular pressure, which is increased until it exceeds the external, residual pressures in
Errors of the Human Body Ruzin of Screen Invasion wrote, ""Errors of the Human Body" is elevated by a sublime turn by star Michael Eklund... His agony, particularly in the third act, is brilliantly painful. Despite the screenplay skimming over his character’s supposed scientific prowess, to the film’s moderate detriment, Eklund’s powerful performance is nonetheless tragic and captivating." Michael Treveloni of Film School Rejects noted, "The film is a not just a science-fiction horror story: it is a commentary on the importance of dialog, showcasing the need for communication in its many forms. With Geoff, "Errors" presents the perfect, damaged subject.". At the Fantastic Fest