Akodon spegazzinii is found in northwestern Argentina, in the provinces of Salta, Catamarca, Tucumán, La Rioja, and Mendoza, at altitudes of . Although its main distribution is in the northern provinces of Salta, Tucumán, and Catamarca, there are also scattered records from the more southern provinces of La Rioja and Mendoza, where it is likely restricted to patches of wet habitat. "Akodon alterus" has been reported from Jujuy, but this record was likely based on misidentified specimens of "A. boliviensis", and records of "Akodon spegazzinii" from Jujuy were based on misidentified "A. sylvanus". "Akodon spegazzinii" is known from a paleontological site in
Bob Mendoza High School, as well as officiated over varsity basketball. All told, Mendoza coached football and baseball at Morse from 1970-2000. As the football team's defensive coordinator, he won five section banners. He also coached baseball at Mission Bay High. In 1982, he coached Sam Horn, the No. 1 baseball draft in the country at the time. The same year, Mark McLemore, who Mendoza also coached, was drafted by the California Angels in the 9th round amateur draft. In 1990, Morse Tigers were ranked No. 4 in the country by USA Today. Mendoza and three teammates were featured in the "San