Systole heart beats—is cued by messages from the brain, reflecting the brain's responses to conditions of the body, such as pain, emotional stress, level of activity, and to ambient conditions including external temperature, time of day, etc. Electrical systole opens voltage-gated sodium, potassium and calcium channels in cells of myocardium tissue. Subsequently, a rise in intracellular calcium triggers the interaction of actin and myosin in the presence of ATP which generates mechanical force in the cells in the form of muscular contraction, or mechanical systole. The contractions generate intra-ventricular pressure, which is increased until it exceeds the external, residual pressures in
Human Tissue Authority the HTA authority over exhumed remains from archaeological sites. The Act governs England, Wales and Northern Ireland. There is separate legislation in Scotland, the Human Tissue (Scotland) Act 2006 and the Authority performs certain tasks on behalf of the Scottish Government (approval of living donation and licensing of establishments storing tissue for human application). The Authority consists of a Chair and eleven Members. Nine members have been appointed by the Secretary of State for Health, one appointed by the Welsh Government, and one member is appointed by the Department of Health, Social Services and Public Safety in Northern Ireland. The