Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Sociopolitical issues of anatomy in America in the 19th century US similarly sought to set the medical profession apart from alternative medicine and other rivals through increased anatomical studies. As a result, the demand for corpses by medical students for dissection studies grew, which in turn propelled widespread medical grave-robbing, social strife and legislative changes to provide anatomists with legal supplies of cadavers. Medical grave robbery prompted anatomy riots in nearly every medical institution and drove changes in legislatures. The increase in importance of anatomy in medical studies also increased society's interest in the human body, which prompted the popularization of anatomy museums. The societal funerary obligation to respect the