Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Bodyworks Voyager: Missions in Anatomy Bodyworks Voyager: Missions in Anatomy Bodyworks Voyager is an educational computer game and action shooter for MS-DOS released in 1994. It was developed by Mythos Software, Inc. and published by Software Marketing Corporation. The game teaches human anatomy, and involves a first-person shooter style component as well as quizzes on the human body. Besides exploring the multiple layers and parts of the human body within the Medical Database, the prime objective of the game is to destroy all infecting microbes in a hospital patient by use of a fighter ship reduced by shrink ray and inserted into the body. All