Pathophysiology of heart failure caused by dysfunction or destruction of cardiac myocytes or their molecular components. In congenital diseases such as Duchenne muscular dystrophy, the molecular structure of individual myocytes is affected. Myocytes and their components can be damaged by inflammation (such as in myocarditis) or by infiltration (such as in amyloidosis). Toxins and pharmacological agents (such as ethanol, cocaine, doxorubicin, and amphetamines) cause intracellular damage and oxidative stress. The most common mechanism of damage is ischemia causing infarction and scar formation. After myocardial infarction, dead myocytes are replaced by scar tissue, deleteriously affecting the function of the myocardium. On echocardiogram, this is manifest
Theology of the Body Theology of the Body Theology of the Body is the topic of a series of 129 lectures given by Pope John Paul II during his Wednesday audiences in St. Peter's Square and the Paul VI Audience Hall between September 5, 1979 and November 28, 1984. It constitutes an analysis on human sexuality. The complete addresses were later compiled and expanded upon in many of John Paul's encyclicals, letters, and exhortations. In "Theology of the Body", John Paul II intends to establish an adequate anthropology in which the human body reveals God. He examines man and woman before the Fall, after