Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Sociopolitical issues of anatomy in America in the 19th century executed, "i.e.", hanged criminals, thus many perceived morbid anatomy for anatomical studies as punishment that is only justified to inflict on the morally condemned. Medical grave robbing incited widespread anger and abhorrence, resulting in at least seventeen full-fledged anatomy riots in the United States between 1785 and 1855, in Connecticut, Vermont, Ohio, and elsewhere. Although a law which outlawed body snatching, and allowed executed criminals to be dissected after death, was passed by the New York legislature after the 1788 riot, medical students continued to face a shortage of cadavers, and so grave robbing persisted These anatomy riots involved citizens