Systole heart beats—is cued by messages from the brain, reflecting the brain's responses to conditions of the body, such as pain, emotional stress, level of activity, and to ambient conditions including external temperature, time of day, etc. Electrical systole opens voltage-gated sodium, potassium and calcium channels in cells of myocardium tissue. Subsequently, a rise in intracellular calcium triggers the interaction of actin and myosin in the presence of ATP which generates mechanical force in the cells in the form of muscular contraction, or mechanical systole. The contractions generate intra-ventricular pressure, which is increased until it exceeds the external, residual pressures in
Muscular hydrostat a constant diameter. Bending of a muscular hydrostat can also occur by the contraction of transverse, radial, or circular muscles which decreases the diameter. Bending is produced by longitudinal muscle activity which maintains a constant length on one side of the structure. The bending of a muscular hydrostat is particularly important in animal tongues. This motion provides the mechanism by which a snake flicks the air with its tongue to sense its surroundings, and it is also responsible for the complexities of human speech. The stiffening of a muscular hydrostat is accomplished by the muscle or connective tissue of the