Otic vesicle Otic vesicle Otic vesicle, or auditory vesicle, consists of either of the two sac-like invaginations formed and subsequently closed off during embryonic development. It is part of the neural ectoderm, which will develop into the membranous labyrinth of the inner ear. This labyrinth is a continuous epithelium, giving rise to the vestibular system and auditory components of the inner ear. During the earlier stages of embryogenesis, the otic placode invaginates to produce the otic cup. Thereafter, the otic cup closes off, creating the otic vesicle. Once formed, the otic vesicle will reside next to the neural tube medially, and on
Surface anatomy and in motion. In addition, the science of surface anatomy includes the theories and systems of body proportions and related artistic canons. The study of surface anatomy is the basis for depicting the human body in classical art. Some pseudo-sciences such as physiognomy, phrenology and palmistry rely on surface anatomy. Knowledge of the surface anatomy of the thorax (chest) is particularly important because it is one of the areas most frequently subjected to physical examination, like auscultation and percussion.In cardiology, Erb's point refers to the third intercostal space on the left sternal border where S2 heart sound is best auscultated.