Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Museum of Human Anatomy Luigi Rolando Museum of Human Anatomy Luigi Rolando The Museum of Human Anatomy Luigi Rolando () is a museum of human anatomy that was founded in 1739 with headquarters in Torino, Italy. It is part of the museum network of the University of Turin and moved to its current location in the Building of the Anatomical Institutes () in 1898. The study of anatomy in Turin began in 1563, with the arrival in town of Savona scholar Angelo Visca, but it was only in 1739 that it was the first collection of anatomical preparations, commissioned by Giovanni Battista Bianchi Carlo Emanuele III