Pathophysiology of heart failure caused by dysfunction or destruction of cardiac myocytes or their molecular components. In congenital diseases such as Duchenne muscular dystrophy, the molecular structure of individual myocytes is affected. Myocytes and their components can be damaged by inflammation (such as in myocarditis) or by infiltration (such as in amyloidosis). Toxins and pharmacological agents (such as ethanol, cocaine, doxorubicin, and amphetamines) cause intracellular damage and oxidative stress. The most common mechanism of damage is ischemia causing infarction and scar formation. After myocardial infarction, dead myocytes are replaced by scar tissue, deleteriously affecting the function of the myocardium. On echocardiogram, this is manifest
Explorers of the Human Body weeks. It was later decided that instead of a hiatus, the program will end the season with thirteen episodes. Super Junior decided to leave the show due to their occupied schedules and busy preparations for their upcoming Asia-wide concert tour, Super Show. However, representatives of the program stated if there is a chance, a second season is considered. "Change", the variety program hosted by Lee Hyo-ri and Shin Dong-yup with Noh Hong-chul, Kangin, Son Ho-young and Min Kyung-hoon as regulars, took over the time slot. Explorers of the Human Body Explorers of the Human Body (Hangul: 인체탐험대; Hanja: 人體探險隊) was