Hibernating myocardium Hibernating myocardium In cardiology, hibernating myocardium is a state when some segments of the myocardium exhibit abnormalities of contractile function. These abnormalities can be visualised with echocardiography, cardiac magnetic resonance imaging (CMR), nuclear medicine (PET) or ventriculography. Echocardiography: A wall motion abnormality at rest which improves during a low-dose dobutamine stress test is classified as "hibernating myocardium". Low dose dobutamine stimulates contractile function and thus helps to predict functional recovery after revascularization. Cardiac magnetic resonance: The most frequently used MR contrast agents based on Gd-chelates accumulate in the extracellular space which is increased in scarred myocardium. This leads to a
Human Tissue Authority March 2018 by Nicola Blackwood. Its objectives are to: It also acts as the UK competent authority under the EU Tissue and Cells Directives. The Human Tissue Act 2004 repeals and replaces the Human Tissue Act 1961, the Anatomy Act 1984 and the Human Organ Transplants Act 1989 as they relate to England and Wales, and the corresponding Orders in Northern Ireland. The ULTRA (UK agency) and the post of HM Inspector of Anatomy were abolished and their functions transferred to the Authority. The Act makes "consent" the fundamental principle underpinning the lawful storage and use of body parts, organs