Otic vesicle constricts to form the canalis reuniens. The central part of the otic vesicle represents the membranous vestibule, and is subdivided by a constriction into a smaller ventral part, the saccule, and a larger dorsal and posterior part, the utricle. The dorsal component of the inner ear also consists of what will become the semicircular canals. The utricle and saccule communicate with each other by means of a Y-shaped canal. The FGF, Bmp, Wnt and Pax genes are likely to be involved in otic induction. FGF and BMP signals help control patterning in the early otic vesicle. Fgf3 and Fgf10 are
Surface anatomy and in motion. In addition, the science of surface anatomy includes the theories and systems of body proportions and related artistic canons. The study of surface anatomy is the basis for depicting the human body in classical art. Some pseudo-sciences such as physiognomy, phrenology and palmistry rely on surface anatomy. Knowledge of the surface anatomy of the thorax (chest) is particularly important because it is one of the areas most frequently subjected to physical examination, like auscultation and percussion.In cardiology, Erb's point refers to the third intercostal space on the left sternal border where S2 heart sound is best auscultated.