Otic vesicle the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcription factors including PAX2, DLX5 and DLX6, with the former specifying for ventral otic vesicle derived auditory structures and the latter two specifying for dorsal vestibular structures. The otic vesicle is derived from the cranial placode. The early otic vesicle is characterized as having broad competence
Errors of the Human Body Errors of the Human Body Errors of the Human Body is a 2012 psychological thriller directed by Eron Sheean and starring Michael Eklund. Dr. Geoff Burton (Eklund), a brilliant genetics researcher, is invited to a lab in Dresden, only to discover a lethal virus is being created, which he may have unintentionally caused and be its first victim. This mystery is set against Dr. Burton trying to find redemption and peace from a past haunted by the death of his infant son. While showing a short film at Berlinale in 2006, Sheean met a scientist from the Max Planck Institute