Systole heart beats—is cued by messages from the brain, reflecting the brain's responses to conditions of the body, such as pain, emotional stress, level of activity, and to ambient conditions including external temperature, time of day, etc. Electrical systole opens voltage-gated sodium, potassium and calcium channels in cells of myocardium tissue. Subsequently, a rise in intracellular calcium triggers the interaction of actin and myosin in the presence of ATP which generates mechanical force in the cells in the form of muscular contraction, or mechanical systole. The contractions generate intra-ventricular pressure, which is increased until it exceeds the external, residual pressures in
Explorers of the Human Body weeks. It was later decided that instead of a hiatus, the program will end the season with thirteen episodes. Super Junior decided to leave the show due to their occupied schedules and busy preparations for their upcoming Asia-wide concert tour, Super Show. However, representatives of the program stated if there is a chance, a second season is considered. "Change", the variety program hosted by Lee Hyo-ri and Shin Dong-yup with Noh Hong-chul, Kangin, Son Ho-young and Min Kyung-hoon as regulars, took over the time slot. Explorers of the Human Body Explorers of the Human Body (Hangul: 인체탐험대; Hanja: 人體探險隊) was