Circulatory system of the horse capacity of the muscular system far exceeds the capacity of the cardiovascular system to deliver oxygen. Blood is made up of red blood cells (erythrocytes) and white blood cells (leukocytes), as well as plasma. Produced in bone marrow, red blood cells are responsible for carrying oxygen to tissue and removing carbon dioxide, all via hemoglobin. White blood cells are used for defense against pathogens in the immune system. Plasma suspends the blood cells, contains clotting factors, and contributes to the greatest volume of blood. The heart and blood vessels contain approximately of blood in a horse, which equates to about
Acetyl-CoA carboxylase of acetyl CoA. The function of ACC is to regulate the metabolism of fatty acids. When the enzyme is active, the product, malonyl-CoA, is produced which is a building block for new fatty acids and can inhibit the transfer of the fatty acyl group from acyl CoA to carnitine with carnitine acyltransferase, which inhibits the beta-oxidation of fatty acids in the mitochondria. In mammals, two main isoforms of ACC are expressed, ACC1 and ACC2, which differ in both tissue distribution and function. ACC1 is found in the cytoplasm of all cells but is enriched in lipogenic tissue, such as adipose