Osmotic nephrosis condition, or it may confused with other nephrotic conditions such as Tubular calcineurin-inhibitor toxicity. Affected cells of the proximal tubule may be passed in the urine, but a kidney biopsy is the only sure way to make a diagnosis. Responsible exogenous solutes include sucrose-containing IVIg, mannitol, dextran, contrast dye, and hydroxyethyl starch. Prevention includes standard preventions for iatrogenic kidney damage. Osmotic nephrosis is usually reversible but can lead to chronic renal failure. Osmotic nephrosis Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to
Degeneration theory government circles. The psychiatrist Henry Maudsley initially argued that degenerate family lines would die out with little social consequence, but later became more pessimistic about the effects of degeneration on the British population. In the "fin-de-siècle" period, Max Nordau scored an unexpected success with his bestselling "Degeneration" (1892). Sigmund Freud met Nordau in 1885 while he was studying in Paris and was notably unimpressed by him and hostile to the degeneration concept. Degeneration fell from popular and fashionable favor around the time of the First World War, although some of its preoccupations persisted in the writings of the eugenicists and