Equine proximal enteritis the intestinal lumen. Inflammation of the intestine leads to the secretion of a large amounts of electrolytes, primarily sodium and chloride, into its lumen, resulting in the osmotic movement of water. The production of fluid is thought to be due to active hypersecretion, passive secretion of proteins secondary to damage to epithelium of the mucosa and capillaries, and a functional ileus which prevents removal of this fluid. Massive fluid production results in extensive reflux, usually produced at a rate of 50–100 mL/min, in addition to distention of the proximal small intestine, dehydration, and possible shock secondary to hypovolemia. Proximal enteritis
Inflammation at a higher level in obese people. It raises when there is inflammation throughout the body. Mild elevation in CRP increases risk of heart attacks, strokes, high blood pressure, asthma exacerbations, muscle weakness and fragility. Hyperglycemia induces IL-6 production from endothelial cells and macrophages. Meals high in saturated fat, as well as meals high in calories have been associated with increases in inflammatory markers. In addition, interstitial abdominal adiposity (also referred to as accumulated intra-abdominal fat) may be a factor in increasing systemic risk for multiple inflammatory diseases. Although the exact mechanisms are still being investigated, a review published in