Domingo Liotta Hospital, Houston, Texas. First Clinical use. 1966 (August 8): Liotta-DeBakey LVAD in a paracorporeal position in cardiogenic shock postcardiotomy, Methodist Hospital, Houston, Texas. First successful clinical use. 1969 (April 4): Liotta-Cooley Total Artificial Heart, Texas Heart Institute, Houston, Texas. First clinical use. http://www.texasheartinstitute.org/Research/Devices/liotta.cfm. This device was stolen from the lab of Dr. Michael E. DeBakey by Liotta. Dr. Cooley was not involved in any way in its development. The device had not been successful in animal experiments, and while the patient had the artificial heart in place he developed multiple system organ failure, as the experimental animals had, and died
Human artificial chromosome Human artificial chromosome A human artificial chromosome (HAC) is a microchromosome that can act as a new chromosome in a population of human cells. That is, instead of 46 chromosomes, the cell could have 47 with the 47th being very small, roughly 6–10megabases (Mb) in size instead of 50–250Mb for natural chromosomes, and able to carry new genes introduced by human researchers. Ideally, researchers could integrate different genes that perform a variety of functions, including disease defense. Alternative methods of creating transgenes, such as utilizing yeast artificial chromosomes and bacterial artificial chromosomes, lead to unpredictable problems. The genetic material introduced