Osmotic nephrosis Osmotic nephrosis Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to the formation of large vacuoles in the cytoplasm. These vacuoles occur in the presence of large amounts of certain solutes circulating in the tubules. However, despite the condition's name, the solutes do not cause change through osmotic forces but through pinocytosis. Once inside the cytoplasm, pinocytic vacuoles combine with each other and with lysosomes to form large vacuoles that appear transparent under microscopic examination. There may be no symptomatic presentation with this
Degeneration (Nordau) Degeneration (Nordau) Degeneration (Entartung, 1892), is a book by Max Nordau in which he attacks what he believed to be degenerate art and comments on the effects of a range of social phenomena of the period, such as rapid urbanization and its perceived effects on the human body. Nordau begins his work with a "medical" and social interpretation of what has created this Degeneration in society. Nordau divides his study into five books. In the first book, Nordau identifies the phenomenon of fin de siècle in Europe. He sees this as first being recognised, though not originating, in France, describing