Osmotic nephrosis condition, or it may confused with other nephrotic conditions such as Tubular calcineurin-inhibitor toxicity. Affected cells of the proximal tubule may be passed in the urine, but a kidney biopsy is the only sure way to make a diagnosis. Responsible exogenous solutes include sucrose-containing IVIg, mannitol, dextran, contrast dye, and hydroxyethyl starch. Prevention includes standard preventions for iatrogenic kidney damage. Osmotic nephrosis is usually reversible but can lead to chronic renal failure. Osmotic nephrosis Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to
Degeneration theory uncomfortably with the difficulties of French political life in the post-revolutionary nineteenth century. Degeneration theory achieved a detailed articulation in Bénédict Morel's "Treatise on Degeneration of the Human Species" (1857), a complicated work of clinical commentary from an asylum in Normandy (Saint Yon in Rouen) which, in the popular imagination at least, coalesced with de Gobineau's "Essay on The Inequality of the Human Races" (1855). Morel's concept of "mental degeneration" - in which he believed that intoxication and addiction in one generation of a family would lead to hysteria, epilepsy, sexual perversions, insanity, learning disability and sterility in subsequent generations