Prime quadruplet 23620, 152141, 1028789, 7188960, 51672312, 381226246, 2873279651 . The constant representing the sum of the reciprocals of all prime quadruplets, Brun's constant for prime quadruplets, denoted by "B", is the sum of the reciprocals of all prime quadruplets: with value: This constant should not be confused with the Brun's constant for cousin primes, prime pairs of the form ("p", "p" + 4), which is also written as "B". The prime quadruplet {11, 13, 17, 19} is alleged to appear on the Ishango bone although this is disputed. Excluding the first prime quadruplet, the shortest possible distance between two quadruplets {"p",
Prime number and the RSA cryptosystem were invented, using prime numbers as their basis. The increased practical importance of computerized primality testing and factorization led to the development of improved methods capable of handling large numbers of unrestricted form. The mathematical theory of prime numbers also moved forward with the Green–Tao theorem (2004) on long arithmetic progressions of prime numbers, and Yitang Zhang's 2013 proof that there exist infinitely many prime gaps of bounded size. Most early Greeks did not even consider 1 to be a number, so they could not consider its primality. A few mathematicians from this time also considered