Bimodal volcanism Bimodal volcanism Bimodal volcanism is the eruption of both mafic and felsic lavas from a single volcanic centre with little or no lavas of intermediate composition. This type of volcanism is normally associated with areas of extensional tectonics, particularly rifts. Most occurrences of bimodal volcanism are associated with thinning of the crust and the presence of such rocks in metamorphic sequences has been used to provide evidence for past rifting events. Most examples come from areas of active continental rifting such as the Basin and Range Province. Bimodal volcanism has also been described from areas of transtension, the early phases
Substance P The sensory function of substance P is thought to be related to the transmission of pain information into the central nervous system. Substance P coexists with the excitatory neurotransmitter glutamate in primary afferents that respond to painful stimulation. Substance P and other sensory neuropeptides can be released from the peripheral terminals of sensory nerve fibers in the skin, muscle, and joints. It is proposed that this release is involved in neurogenic inflammation, which is a local inflammatory response to certain types of infection or injury. Unfortunately, the reasons why NK1RAs have failed as efficacious analgesics in well-conducted clinical proof of