Volcanic plateau up by foundering of the Earth's crust to form the present ocean basin. The Earth features numerous subaerial and submarine volcanic plateaus such as the Columbia River Plateau (subaerial) and the vast Ontong Java Plateau (submarine). Pyroclastic plateaus are produced by massive pyroclastic flows and they are underlain by pyroclastic rocks: agglomerates, tephra, volcanic ashes cemented into tuffs, mafic or felsic. Examples include Shirasu-Daichi which covers almost all of Southern Kyūshū, Japan and the North Island Volcanic Plateau in New Zealand. Volcanic plateau A volcanic plateau is a plateau produced by volcanic activity. There are two main types: lava plateaus
Substance P The sensory function of substance P is thought to be related to the transmission of pain information into the central nervous system. Substance P coexists with the excitatory neurotransmitter glutamate in primary afferents that respond to painful stimulation. Substance P and other sensory neuropeptides can be released from the peripheral terminals of sensory nerve fibers in the skin, muscle, and joints. It is proposed that this release is involved in neurogenic inflammation, which is a local inflammatory response to certain types of infection or injury. Unfortunately, the reasons why NK1RAs have failed as efficacious analgesics in well-conducted clinical proof of