Artificial organ a stationary power supply or other stationary resources such as filters or chemical processing units. (Periodic rapid recharging of batteries, refilling of chemicals, and/or cleaning/replacing of filters would exclude a device from being called an artificial organ.) Thus, a dialysis machine, while a very successful and critically important life support device that almost completely replaces the duties of a kidney, is not an artificial organ. Constructing and installing artificial organs, an extremely research-intensive and expensive process initially, may entail many years of ongoing maintenance services not needed by a natural organ.: The use of any artificial organ by humans is
Transneuronal degeneration located closer more superficially. This provided them with them hypothesis that olfactory bulb removal results in transneuronal deafferentation as a result of the massive sudden loss of input from the removed brain tissue. Unilateral perforant pathway transection is a method to study how transneuronal degeneration results from denervation in the Central Nervous System. Studies are still being done to solidify to connection between candidate molecules creating changes in the central nervous system and postleisonal changes. Current studies in rats and mice have provided evidence that microglia cells contribute to transneuronal degeneration of parvalbumin-positive dendrites. Denervation in the entorhinal-hippicampal area of