Domingo Liotta shortly thereafter. 1962 (May): Prolonged assisted circulation during and after cardiac and aortic surgery. Prolonged partial left ventricular bypass by means of intracorporeal circulation. It was selected as Finalist for the Young Investigators´ Contest Award (Denver) of the American College of Cardiology. 1964: Annual Award, Southwestern Surgical Society, USA. Shared with C. William Hall and Michael E. DeBakey.1968: Golden Eagle Award, Council of International Nontheatrical Events, USA, shared with Denton A. Cooley, Robert Bloodwell, and Grady Hallman. 1969: Award of Merit, American Medical Association shared with Denton A. Cooley, MD. 1969: Decoration of the Institute of Spanish Culture, Madrid, Spain.
Artificial cell cells have been proposed as a non-viral vector by which genetically modified non-autologous cells are encapsulated and implanted to deliver recombinant proteins "in vivo". This type of immuno-isolation has been proven efficient in mice through delivery of artificial cells containing mouse growth hormone which rescued a growth-retardation in mutant mice. A few strategies have advanced to human clinical trials for the treatment of pancreatic cancer, lateral sclerosis and pain control. The first clinical use of artificial cells was in hemoperfusion by the encapsulation of activated charcoal. Activated charcoal has the capability of adsorbing many large molecules and has for a