Domingo Liotta his studies, Dr. Liotta was hired at Baylor College of Medicine in Houston Texas as Director of the Artificial Heart Program by Dr. Michael E. DeBakey in 1961. 1961(December): First conception of the prolonged mechanical assist circulation in the treatment of Cardiogenic Shock Postcardiotomy. 1963 (July 19): Left Ventricular Assist Device (LVAD) in a patient in cardiogenic shock postcardiotomy, Domingo Liotta and E. Stanley Crawford at the Methodist Hospital in Houston, Texas. First clinical use. The original clinical prototype is displayed at the Smithsonian Institution, Washington, D.C.. 1966 (April 21): Liotta-DeBakey LVAD implanted in a cardiogenic shock postcardiotomy patient, Methodist
Artificial cell cells have been proposed as a non-viral vector by which genetically modified non-autologous cells are encapsulated and implanted to deliver recombinant proteins "in vivo". This type of immuno-isolation has been proven efficient in mice through delivery of artificial cells containing mouse growth hormone which rescued a growth-retardation in mutant mice. A few strategies have advanced to human clinical trials for the treatment of pancreatic cancer, lateral sclerosis and pain control. The first clinical use of artificial cells was in hemoperfusion by the encapsulation of activated charcoal. Activated charcoal has the capability of adsorbing many large molecules and has for a