Domingo Liotta his studies, Dr. Liotta was hired at Baylor College of Medicine in Houston Texas as Director of the Artificial Heart Program by Dr. Michael E. DeBakey in 1961. 1961(December): First conception of the prolonged mechanical assist circulation in the treatment of Cardiogenic Shock Postcardiotomy. 1963 (July 19): Left Ventricular Assist Device (LVAD) in a patient in cardiogenic shock postcardiotomy, Domingo Liotta and E. Stanley Crawford at the Methodist Hospital in Houston, Texas. First clinical use. The original clinical prototype is displayed at the Smithsonian Institution, Washington, D.C.. 1966 (April 21): Liotta-DeBakey LVAD implanted in a cardiogenic shock postcardiotomy patient, Methodist
Human artificial chromosome Human artificial chromosome A human artificial chromosome (HAC) is a microchromosome that can act as a new chromosome in a population of human cells. That is, instead of 46 chromosomes, the cell could have 47 with the 47th being very small, roughly 6–10megabases (Mb) in size instead of 50–250Mb for natural chromosomes, and able to carry new genes introduced by human researchers. Ideally, researchers could integrate different genes that perform a variety of functions, including disease defense. Alternative methods of creating transgenes, such as utilizing yeast artificial chromosomes and bacterial artificial chromosomes, lead to unpredictable problems. The genetic material introduced