Free fatty acid receptor 2 between the pathways activated by FFAR2 agonists in human cells and the equivalent murine counterparts have been observed. FFAR2 may interact with FFAR3 to form a FFAR2-FFAR3 receptor heteromer with signalling that is distinct from the parent homomers. Free fatty acid receptor 2 Free fatty acid receptor 2 (FFAR2) is a G-protein coupled receptor encoded by the FFAR2 gene. FFAR2 mRNA is expressed in adipose tissue, pancreas, spleen, lymph nodes, bone marrow, and peripheral blood mononuclear cells. FFAR2 transcription is regulated by the XBP1 transcription factor which binds to the core promoter. Mouse studies utilizing Ffar2 gene deletions have implicated
The Bones of What You Believe derives from a lyric in the song "Strong Hand"; according to frontwoman Lauren Mayberry, it refers to the raw "creativity and effort" that served as the figurative and literal skeleton for the album. Musically, "The Bones of What You Believe" is primarily a synth-pop and indie pop album that incorporates "neon-Eighties" influences. "The Bones of What You Believe" received critical acclaim, with many complimenting Mayberry's songwriting and vocal performance, and Iain Cook and Martin Doherty's use of synthesisers and vocal loops. The album debuted at number nine on the UK Albums Chart, selling 12,415 copies in its first week. It