Ancient Greece and wine have been uncovered by archaeologists, demonstrating the scope of Greek influence. A shipwreck discovered off the coast of southern France included nearly 10,000 amphoras containing nearly of Greek wine, presumably destined for trade up the Rhône and Saône rivers into Gaul. It is estimated that the Greeks shipped nearly 10 million liters of wine into Gaul each year through Massalia. In 1929, the discovery of the Vix Grave in Burgundy included several artifacts demonstrating the strong ties between Greek wine traders and local Celtic villagers. The most notable of these was a large Greek-made krater, designed to hold over of
Ancient Rome and wine surgery. When he became Emperor Marcus Aurelius's physician, he developed pharmaceutical concoctions made from wine known as theriacs. Superstitious beliefs concerning theriacs' "miraculous" ability to protect against poisons and cure everything from the plague to mouth sores lasted until the 18th century. In his work "De Antidotis", Galen noted the trend in Romans' tastes from thick, sweet wines to lighter, dry wines that were easier to digest. The Romans were also aware of the negative health effects of drinking wine, particularly the tendency towards "madness" if consumed immoderately. Lucretius warned that wine could provoke a fury in one's soul and