Nephrosis nephritic complications. In other words, nephrosis and nephritis can be pathophysiologically contradistinguished, but that does not mean that they cannot occur simultaneously. Types of nephrosis include amyloid nephrosis and osmotic nephrosis. Nephrosis Nephrosis is any of various forms of kidney disease (nephropathy). In an old and broad sense of the term, it is any nephropathy, but in current usage the term is usually restricted to a narrower sense of nephropathy without inflammation or neoplasia, in which sense it is distinguished from nephritis, which involves inflammation. It is also defined as any purely degenerative disease of the renal tubules. Nephrosis is
Transneuronal degeneration neurons in the substantia nigra pars reticulata. The reorganization of cellular structures that results from transneuronal degeneration can be seen in Alzheimer's disease. It is hypothesized that anterograde transneuronal degeneration causes the hyperphosphorylation of the tau protein and redistributing those proteins from the axon to the dendrites, which begins the breakdown of routing and sorting mechanisms. Cockayne syndrome results from a mutation in genes that interfere with transcription-coupled repair of nuclear and mitochondrial DNA, replication, and transcription. Neuronal death is predominantly in the cerebellum, but this disease also causes apoptosis in purkinje cells and causes them to have dystrophic dendrites.