Prime number the 1970s, mathematicians and physicists have speculated that the zeros of the Riemann zeta function are connected to the energy levels of quantum systems. Prime numbers are also significant in quantum information science, thanks to mathematical structures such as mutually unbiased bases and symmetric informationally complete positive-operator-valued measures. The evolutionary strategy used by cicadas of the genus "Magicicada" makes use of prime numbers. These insects spend most of their lives as grubs underground. They only pupate and then emerge from their burrows after 7, 13 or 17 years, at which point they fly about, breed, and then die after a
Prime number theorem , the probability that a random integer not greater than is prime is very close to . Consequently, a random integer with at most digits (for large enough ) is about half as likely to be prime as a random integer with at most digits. For example, among the positive integers of at most 1000 digits, about one in 2300 is prime (), whereas among positive integers of at most 2000 digits, about one in 4600 is prime (). In other words, the average gap between consecutive prime numbers among the first integers is roughly . Let be the prime-counting