Red blood cell blood circulation for about 100 to 120 days (and 80 to 90 days in a full term infant). At the end of their lifespan, they are removed from circulation. In many chronic diseases, the lifespan of the red blood cells is reduced. Erythropoiesis is the process by which new red blood cells are produced; it lasts about 7 days. Through this process red blood cells are continuously produced in the red bone marrow of large bones. (In the embryo, the liver is the main site of red blood cell production.) The production can be stimulated by the hormone erythropoietin (EPO),
Generative tissue and has a unique cellular and biochemical make-up that make it distinct from other tissues of the body. gTissue was discovered through research in the fields of Tissue Engineering and Regenerative Medicine and first created as a dense connective tissue between the brain and skull during the repair of canine dura mater. It has since been successfully created in humans for a wide range of clinical applications in soft tissue healing and repair. Essentially, the gTissue is created by implanting certain types of non-inflammatory ECM biomaterials that are adopted by the host, including repopulation with host cells and blood vessels,