Osmotic nephrosis Osmotic nephrosis Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to the formation of large vacuoles in the cytoplasm. These vacuoles occur in the presence of large amounts of certain solutes circulating in the tubules. However, despite the condition's name, the solutes do not cause change through osmotic forces but through pinocytosis. Once inside the cytoplasm, pinocytic vacuoles combine with each other and with lysosomes to form large vacuoles that appear transparent under microscopic examination. There may be no symptomatic presentation with this
Resident Evil: Degeneration Resident Evil: Degeneration Resident Evil: Degeneration, known in Japan as , is a biopunk action horror film directed by Makoto Kamiya. It is the first full-length motion capture CG animation feature in Capcom's "Resident Evil" franchise. The film was made by Capcom in cooperation with Sony Pictures Entertainment Japan. "Degeneration" made its premiere in Japan on October 11, 2008 at the Tokyo Game Show, and was released nationwide one week later on October 18. Unlike the "Resident Evil" live-action film series, "Degeneration" is set within the same universe as the original video game series. The main characters are Leon S.