Atomic number and the mass defect of nucleon binding is always small compared to the nucleon mass, the atomic mass of any atom, when expressed in unified atomic mass units (making a quantity called the "relative isotopic mass"), is within 1% of the whole number "A". Atoms with the same atomic number "Z" but different neutron numbers "N", and hence different atomic masses, are known as isotopes. A little more than three-quarters of naturally occurring elements exist as a mixture of isotopes (see monoisotopic elements), and the average isotopic mass of an isotopic mixture for an element (called the relative atomic mass)
Atomic number were now recognized to be the same as the element number, was not understood. An old idea called Prout's hypothesis had postulated that the elements were all made of residues (or "protyles") of the lightest element hydrogen, which in the Bohr-Rutherford model had a single electron and a nuclear charge of one. However, as early as 1907 Rutherford and Thomas Royds had shown that alpha particles, which had a charge of +2, were the nuclei of helium atoms, which had a mass four times that of hydrogen, not two times. If Prout's hypothesis were true, something had to be neutralizing