Red blood cell blood circulation for about 100 to 120 days (and 80 to 90 days in a full term infant). At the end of their lifespan, they are removed from circulation. In many chronic diseases, the lifespan of the red blood cells is reduced. Erythropoiesis is the process by which new red blood cells are produced; it lasts about 7 days. Through this process red blood cells are continuously produced in the red bone marrow of large bones. (In the embryo, the liver is the main site of red blood cell production.) The production can be stimulated by the hormone erythropoietin (EPO),
The Bones of What You Believe derives from a lyric in the song "Strong Hand"; according to frontwoman Lauren Mayberry, it refers to the raw "creativity and effort" that served as the figurative and literal skeleton for the album. Musically, "The Bones of What You Believe" is primarily a synth-pop and indie pop album that incorporates "neon-Eighties" influences. "The Bones of What You Believe" received critical acclaim, with many complimenting Mayberry's songwriting and vocal performance, and Iain Cook and Martin Doherty's use of synthesisers and vocal loops. The album debuted at number nine on the UK Albums Chart, selling 12,415 copies in its first week. It