Lava Vesuvius between May 14 and June 4, 1737. Serao described "a flow of fiery lava" as an analogy to the flow of water and mud down the flanks of the volcano following heavy rain. The composition of almost all lava of the Earth's crust is dominated by silicate minerals, mostly feldspars, olivine, pyroxenes, amphiboles, micas and quartz. Igneous rocks, which form lava flows when erupted, can be classified into three chemical types: "felsic", "intermediate", and "mafic" (four if one includes the super-heated "ultramafic"). These classes are primarily chemical, however, the chemistry of lava also tends to correlate with the magma
Substance P The sensory function of substance P is thought to be related to the transmission of pain information into the central nervous system. Substance P coexists with the excitatory neurotransmitter glutamate in primary afferents that respond to painful stimulation. Substance P and other sensory neuropeptides can be released from the peripheral terminals of sensory nerve fibers in the skin, muscle, and joints. It is proposed that this release is involved in neurogenic inflammation, which is a local inflammatory response to certain types of infection or injury. Unfortunately, the reasons why NK1RAs have failed as efficacious analgesics in well-conducted clinical proof of