Equine proximal enteritis the intestinal lumen. Inflammation of the intestine leads to the secretion of a large amounts of electrolytes, primarily sodium and chloride, into its lumen, resulting in the osmotic movement of water. The production of fluid is thought to be due to active hypersecretion, passive secretion of proteins secondary to damage to epithelium of the mucosa and capillaries, and a functional ileus which prevents removal of this fluid. Massive fluid production results in extensive reflux, usually produced at a rate of 50–100 mL/min, in addition to distention of the proximal small intestine, dehydration, and possible shock secondary to hypovolemia. Proximal enteritis
Neoteny in humans complex gene networks, as predicted by this model. The researchers behind the theory argue that neoteny is a side effect of the destruction of gene networks preventing the firing of genetic activity patterns that marked adulthood in prehuman ancestors. Desmond Collins who was an Extension Lecturer of Archaeology at London University said that the lengthened youth period of humans is part of neoteny. Physical anthropologist Barry Bogin said that the pattern of children's growth may intentionally increase the duration of their cuteness. Bogin said that the human brain reaches adult size when the body is only 40 percent complete, when