Bone exclusively with red marrow or hematopoietic marrow, but as the child ages the hematopoietic fraction decreases in quantity and the fatty/ yellow fraction called marrow adipose tissue (MAT) increases in quantity. In adults, red marrow is mostly found in the bone marrow of the femur, the ribs, the vertebrae and pelvic bones. Bone is a metabolically active tissue composed of several types of cells. These cells include osteoblasts, which are involved in the creation and mineralization of bone tissue, osteocytes, and osteoclasts, which are involved in the reabsorption of bone tissue. Osteoblasts and osteocytes are derived from osteoprogenitor cells, but
Generative tissue becoming a living tissue. To date, the types of gTissue created can be characterized as variants of soft connective tissues including dermis, tendon, ligament, and fascia. Initially the cell-free ECM biomaterial is implanted and progressively adopted by the host. Immediately upon surgical implantation, the porous material becomes soaked in blood. This seeds the material with a population of circulating stem cells, and growth factors to support gTissue development. As generation progresses, the growth factors, cytokines, and fibrin provisional matrix signals host cells to repopulate the matrix. To support the metabolic activity of these cells, a vascular network is simultaneously created