Free fatty acid receptor 2 Free fatty acid receptor 2 Free fatty acid receptor 2 (FFAR2) is a G-protein coupled receptor encoded by the FFAR2 gene. FFAR2 mRNA is expressed in adipose tissue, pancreas, spleen, lymph nodes, bone marrow, and peripheral blood mononuclear cells. FFAR2 transcription is regulated by the XBP1 transcription factor which binds to the core promoter. Mouse studies utilizing Ffar2 gene deletions have implicated the receptor in the regulation of energy metabolism and immune responses. Short Chain Fatty Acids (SCFA's) generated in the processing of fiber by intestinal microbiota act as ligands for the receptor and can affect neutrophil chemotaxis. However, discrepancies
Dental pulp stem cells growth, differentiation, and angiogenic potential of HDPCs. Results suggest that these metaphosphates may be candidates for dental pulp tissue engineering and regenerative endodontics. Dental pulp is the soft living tissue inside a tooth. Stem cells are found inside the soft living tissue. Scientists have identified the mesenchymal type of stem cell inside dental pulp. This particular type of stem cell has the future potential to differentiate into a variety of other cell types including: Dental pulp stem cells Dental pulp stem cells (DPSCs) are stem cells present in the dental pulp, the soft living tissue within teeth. They are multipotent,