Osmotic nephrosis Osmotic nephrosis Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to the formation of large vacuoles in the cytoplasm. These vacuoles occur in the presence of large amounts of certain solutes circulating in the tubules. However, despite the condition's name, the solutes do not cause change through osmotic forces but through pinocytosis. Once inside the cytoplasm, pinocytic vacuoles combine with each other and with lysosomes to form large vacuoles that appear transparent under microscopic examination. There may be no symptomatic presentation with this
Organ donation in Australia 1.3). In Australia around 1600 people are on the organ transplant waiting list at any time. Less than 1% of persons whose death is in hospital can be potential donors because of the limited circumstances for which organ donation is possible. In 2013 only 40% of patients on the organ wait list received a transplant and 2% of the patients on the waiting list died while waiting for an organ. "Table 1.3 source: Australian Government Organ and Tissue Donation and Transplantation Authority (2014). Annual Report." "Table 1.4 Source: Australian Government Organ and Tissue and Transplantation Authority (2014). Facts and Statistics."