Enteritis in the small intestine, causing malabsorption, as well as inducing secretion of water. It has also been observed to cause villus ischemia, and increase intestinal motility. The net result of these changes is induced diarrhoea. Enteritis necroticans is an often fatal illness, caused by β-toxin of "Clostridium perfringens". This causes inflammation and segments of necrosis throughout the gastrointestinal tract. It is most common in developing countries, however has also been documented in post-World War II Germany. Risk factors for enteritis necroticans include decreased trypsin activity, which prevent intestinal degradation of the toxin, and reduced intestinal motility, which increases likelihood of
Cold and heat adaptations in humans Cold and heat adaptations in humans Cold and heat adaptations in humans are a part of the broad adaptability of "Homo sapiens". Adaptations in humans can be physiological, genetic, or cultural, which allow people to live in a wide variety of climates. There has been a great deal of research done on developmental adjustment, acclimatization, and cultural practices, but less research on genetic adaptations to cold and heat temperatures. The human body always works to remain in homeostasis. One form of homeostasis is thermoregulation. Body temperature varies in every individual, but the average internal temperature is 37.0 °C (98.6 °F).