Geology of the Northwest Territories province from dikes and mafic lava flows, overlain by deep ocean turbidite deposits. These rocks are believed to be the remains of oceanic crust that ended up preserved, surrounded on all sides by felsic volcanic rocks and granitoid plutons. In the area of Snofleld Lake in the northern part of the Slave Province, the remains of Archean stromatolites are preserved in a dolomite unit between felsic volcanic and greywacke-mudstone turbidites, some of the earliest evidence of life, forming in the shallows around volcanic islands. Around 1.27 billion years ago in the Proterozoic, a series of major magmatic events affected the
Substance P The sensory function of substance P is thought to be related to the transmission of pain information into the central nervous system. Substance P coexists with the excitatory neurotransmitter glutamate in primary afferents that respond to painful stimulation. Substance P and other sensory neuropeptides can be released from the peripheral terminals of sensory nerve fibers in the skin, muscle, and joints. It is proposed that this release is involved in neurogenic inflammation, which is a local inflammatory response to certain types of infection or injury. Unfortunately, the reasons why NK1RAs have failed as efficacious analgesics in well-conducted clinical proof of