Free fatty acid receptor 2 Free fatty acid receptor 2 Free fatty acid receptor 2 (FFAR2) is a G-protein coupled receptor encoded by the FFAR2 gene. FFAR2 mRNA is expressed in adipose tissue, pancreas, spleen, lymph nodes, bone marrow, and peripheral blood mononuclear cells. FFAR2 transcription is regulated by the XBP1 transcription factor which binds to the core promoter. Mouse studies utilizing Ffar2 gene deletions have implicated the receptor in the regulation of energy metabolism and immune responses. Short Chain Fatty Acids (SCFA's) generated in the processing of fiber by intestinal microbiota act as ligands for the receptor and can affect neutrophil chemotaxis. However, discrepancies
Spongy tissue problem is particularly common, giving soft, white, 'corky' tissue. Spongy tissue is also a type of animal tissue which contains smooth muscles, fibrous tissues, spaces, veins, and arteries. An example is the corpus spongiosum penis. In bone, the spongy tissue is called cancellous tissue. Spongy tissue Spongy tissue is a type of tissue found both in plants and animals. In plants, it is part of the mesophyll, where it forms a layer next to the palisade cells in the leaf. The spongy mesophyll's function is to allow for the interchange of gases (CO2) that are needed for photosynthesis. The spongy