Reticular connective tissue many free blood cells (largely lymphocytes) in lymph nodes, the spleen, and red bone marrow. There are more than 20 types of reticular fibers. In Reticular Connective Tissue type III collagen/reticular fiber (100-150 nm in diameter) is the major fiber component. It forms the architectural framework of liver, adipose tissue, bone marrow, spleen and basement membrane, to name a few. Notes Reticular connective tissue Reticular connective tissue is a type of connective tissue with a network of reticular fibers, made of type III collagen ("reticulum" = net or network). Reticular fibers are not unique to reticular connective tissue, but only
Tissue remodeling In the proliferation phase, inflammatory cells die by apoptosis, being replaced by myofibroblasts which produce large amounts of collagen. In the maturation phase, myofibroblast numbers are reduced by apoptosis, allowing for infiltration by endothelial cells (for blood vessels) and cardiomyocytes (heart tissue cells). Usually, however, much of the tissue remodeling is pathological, resulting in a large amount of fibrous tissue. By contrast, aerobic exercise can produce beneficial cardiac tissue remodeling in those suffering from left ventricular hypertrophy. Vascular remodeling refers to a compensatory change in blood vessel walls due to plaque growth. Vascular expansion is called positive remodeling, whereas vascular