Free fatty acid receptor 2 between the pathways activated by FFAR2 agonists in human cells and the equivalent murine counterparts have been observed. FFAR2 may interact with FFAR3 to form a FFAR2-FFAR3 receptor heteromer with signalling that is distinct from the parent homomers. Free fatty acid receptor 2 Free fatty acid receptor 2 (FFAR2) is a G-protein coupled receptor encoded by the FFAR2 gene. FFAR2 mRNA is expressed in adipose tissue, pancreas, spleen, lymph nodes, bone marrow, and peripheral blood mononuclear cells. FFAR2 transcription is regulated by the XBP1 transcription factor which binds to the core promoter. Mouse studies utilizing Ffar2 gene deletions have implicated
Generative tissue and has a unique cellular and biochemical make-up that make it distinct from other tissues of the body. gTissue was discovered through research in the fields of Tissue Engineering and Regenerative Medicine and first created as a dense connective tissue between the brain and skull during the repair of canine dura mater. It has since been successfully created in humans for a wide range of clinical applications in soft tissue healing and repair. Essentially, the gTissue is created by implanting certain types of non-inflammatory ECM biomaterials that are adopted by the host, including repopulation with host cells and blood vessels,