Pisiform bone evolutionary benefits from having a shorter pisiform bone, including facilitating ulnar deviation of the hand and preventing hyperextension of the wrist, motions that improve the action of clubbing. Pisiform bone The pisiform bone ( or ), also spelled pisiforme (from the Latin "pisifomis", pea-shaped), is a small knobbly, sesamoid bone that is found in the wrist. It forms the ulnar border of the carpal tunnel. The pisiform is a sesamoid bone, with no covering membrane of periosteum. It is the last carpal bone to ossify. The pisiform bone is a small bone found in the proximal row of the wrist
Effect of spaceflight on the human body adult. In space, however, there is an increase in osteoclast activity due to microgravity. This is a problem, because osteoclasts break down the bones into minerals that are reabsorbed by the body. Osteoblasts are not consecutively active with the osteoclasts, causing the bone to be constantly diminished with no recovery. This increase in osteoclasts activity has been seen particularly in the pelvic region, because this is the region which carries the biggest load with gravity present. A study demonstrated that in healthy mice, osteoclasts appearance increased by 197%, accompanied by a down-regulation of osteoblasts and growth factors that are known