Osmotic nephrosis condition, or it may confused with other nephrotic conditions such as Tubular calcineurin-inhibitor toxicity. Affected cells of the proximal tubule may be passed in the urine, but a kidney biopsy is the only sure way to make a diagnosis. Responsible exogenous solutes include sucrose-containing IVIg, mannitol, dextran, contrast dye, and hydroxyethyl starch. Prevention includes standard preventions for iatrogenic kidney damage. Osmotic nephrosis is usually reversible but can lead to chronic renal failure. Osmotic nephrosis Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to
Transneuronal degeneration located closer more superficially. This provided them with them hypothesis that olfactory bulb removal results in transneuronal deafferentation as a result of the massive sudden loss of input from the removed brain tissue. Unilateral perforant pathway transection is a method to study how transneuronal degeneration results from denervation in the Central Nervous System. Studies are still being done to solidify to connection between candidate molecules creating changes in the central nervous system and postleisonal changes. Current studies in rats and mice have provided evidence that microglia cells contribute to transneuronal degeneration of parvalbumin-positive dendrites. Denervation in the entorhinal-hippicampal area of