Mass number can be near-integer, but at the same time not corresponding to the mass of any natural isotope. For example, bromine has only two stable isotopes, Br and Br, naturally present in approximately equal fractions, which leads to the standard atomic mass of bromine close to 80 (79.904 g/mol), even though the isotope Br with such mass is unstable. Mass number The mass number (symbol "A", from the German word "Atomgewicht" (atomic weight), also called atomic mass number or nucleon number, is the total number of protons and neutrons (together known as nucleons) in an atomic nucleus. It determines the atomic
Hydrogen–deuterium exchange can be measured at atomic resolution quantitatively by neutron crystallography, and in real time if exchange is conducted during the diffraction experiment. High intensity neutron beams are generally generated by spallation at linac particle accelerators such as the Spallation Neutron Source. Neutrons diffract crystals similarly to X-rays and can be used for structural determination. Hydrogen atoms, with between one and zero electrons in a biological setting, diffract X-rays poorly and are effectively invisible under normal experimental conditions. Neutrons scatter from atomic nuclei, and are therefore capable of detecting hydrogen and deuterium atoms. Hydrogen atoms are routinely replaced with deuterium, which