Free fatty acid receptor 2 Free fatty acid receptor 2 Free fatty acid receptor 2 (FFAR2) is a G-protein coupled receptor encoded by the FFAR2 gene. FFAR2 mRNA is expressed in adipose tissue, pancreas, spleen, lymph nodes, bone marrow, and peripheral blood mononuclear cells. FFAR2 transcription is regulated by the XBP1 transcription factor which binds to the core promoter. Mouse studies utilizing Ffar2 gene deletions have implicated the receptor in the regulation of energy metabolism and immune responses. Short Chain Fatty Acids (SCFA's) generated in the processing of fiber by intestinal microbiota act as ligands for the receptor and can affect neutrophil chemotaxis. However, discrepancies
Mucous membrane of the soft palate amount of adenoid tissue. The palatine glands form a continuous layer on its posterior surface and around the uvula. They are primarily mucus-secreting glands, as opposed to serous or mixed secreting glands. Mucous membrane of the soft palate The mucous membrane of the soft palate is thin, and covered with stratified squamous epithelium on both surfaces, except near the pharyngeal ostium of the auditory tube, where it is columnar and ciliated. According to Klein, the mucous membrane on the nasal surface of the soft palate in the fetus is covered throughout by columnar ciliated epithelium, which subsequently becomes squamous; some