Mount Meager massif are covered with their eruptive products and serve as the surface expressions of intrusions. As a result, they provide a unique opportunity to study the relationships between magma chambers and their lavas. The mafic (rich in magnesium and iron), intermediate (between mafic and felsic) and felsic (rich in feldspar and quartz) volcanic rocks of the massif were erupted from at least eight volcanic vents. The Bridge River Vent is a relatively young volcanic crater that formed during an eruption about 2,400 years ago. This eruption ranged in character from explosive to effusive and involved lava dome extrusion, pyroclastic flows, lahars
Substance P The sensory function of substance P is thought to be related to the transmission of pain information into the central nervous system. Substance P coexists with the excitatory neurotransmitter glutamate in primary afferents that respond to painful stimulation. Substance P and other sensory neuropeptides can be released from the peripheral terminals of sensory nerve fibers in the skin, muscle, and joints. It is proposed that this release is involved in neurogenic inflammation, which is a local inflammatory response to certain types of infection or injury. Unfortunately, the reasons why NK1RAs have failed as efficacious analgesics in well-conducted clinical proof of