Free fatty acid receptor 2 between the pathways activated by FFAR2 agonists in human cells and the equivalent murine counterparts have been observed. FFAR2 may interact with FFAR3 to form a FFAR2-FFAR3 receptor heteromer with signalling that is distinct from the parent homomers. Free fatty acid receptor 2 Free fatty acid receptor 2 (FFAR2) is a G-protein coupled receptor encoded by the FFAR2 gene. FFAR2 mRNA is expressed in adipose tissue, pancreas, spleen, lymph nodes, bone marrow, and peripheral blood mononuclear cells. FFAR2 transcription is regulated by the XBP1 transcription factor which binds to the core promoter. Mouse studies utilizing Ffar2 gene deletions have implicated
Moore v. Regents of the University of California because of the potentially fatal amount of swelling in Moore's spleen. Moore signed a written consent form, authorizing the procedure. It said the hospital could "dispose of any severed tissue or member by cremation," and his spleen was removed by surgeons, who were not named as defendants, at UCLA Medical Center. Moore's blood profile returned to normal after only a few days, and further examination of his spleen led Golde to discover that Moore's blood cells were unique in that they produced a protein that stimulated the growth of white blood cells, which help to protect the body from infections.