Isambard Kingdom Brunel to design Brunel Manor and its gardens to be his country home. He never saw the house or gardens finished, as he died before it was completed. Brunel, a heavy smoker, who had been diagnosed with Bright's disease (nephritis), suffered a stroke on 5 September 1859, just before the "Great Eastern" made her first voyage to New York. He died ten days later at the age of 53 and was buried, like his father, in Kensal Green Cemetery in London. He left behind his wife Mary and three children: Isambard Brunel Junior (1837–1902), Henry Marc Brunel (1842–1903) and Florence Mary
Isambard Kingdom Brunel abandoned works at Rotherhithe to further his abortive "Gaz" experiments. This was based on an idea of his father's, and was intended to develop into an engine that ran on power generated from alternately heating and cooling carbon dioxide made from ammonium carbonate and sulphuric acid. Despite interest from several parties (the Admiralty included) the experiments were judged by Brunel to be a failure on the grounds of fuel economy alone, and were discontinued after 1834. In 1865, the East London Railway Company purchased the Thames Tunnel for £200,000, and four years later the first trains passed through it. Subsequently,