Osmotic nephrosis Osmotic nephrosis Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to the formation of large vacuoles in the cytoplasm. These vacuoles occur in the presence of large amounts of certain solutes circulating in the tubules. However, despite the condition's name, the solutes do not cause change through osmotic forces but through pinocytosis. Once inside the cytoplasm, pinocytic vacuoles combine with each other and with lysosomes to form large vacuoles that appear transparent under microscopic examination. There may be no symptomatic presentation with this
Corticobasal degeneration need to go, due to eventual loss of speech. Therefore, proper hygiene is mandatory to prevent urinary tract infections. CBgD was first identified by Rebeiz and his associates in 1968, as they observed three individuals who exhibited characteristic symptoms of the unique and previously unknown disorder. They initially referred to the neurodegenerative disease as "corticodentatonigral degeneration with neuronal achromasia", after which various other names were used, including "corticonigral degeneration with nuclear achromasia" and "cortical basal ganglionic degeneration". Although the underlying cause of CBgD is unknown, the disease occurs as a result of damage to the basal ganglia, specifically marked by