Domingo Liotta Author of the Law 20748, The National System of Public Health. 1991-94: Surgeon-in-Chief, Cardiovascular Clinic Institute, Buenos Aires, Argentina. 1994-96: Secretary of State for Science and Technology and President of the National Council of Scientific and Technological Research (CONICET), Argentina. 1997–present: Dean of the School of Medicine, University of Morón, Argentina Member of numerous Medical Societies around the world. Owner of 12 patent inventions in USA, Argentina and France. Author of hundreds of scientific publications and scientific books. Author of medical humanism books in English and Spanish. Recently published his autobiography,"Amazing Adventures of a Heart Surgeon. The Artificial Heart: The
Human artificial chromosome resulted in a human artificial chromosome that is mitotically stable. 21HAC was also able to be transferred into cells from a variety of species (mice, chickens, humans). Using 21HAC, researchers were able to insert a herpes simplex virus- thymidine kinase coding gene into tumor cells. This "suicide gene" is required to activate many antiviral medications. These targeted tumor cells were successfully, and selectively, terminated by the antiviral drug ganciclovir in a population including healthy cells. This research opens a variety of opportunities for using HACs in gene therapy. In 2011, researchers formed a human artificial chromosome by truncating chromosome 14.