Domingo Liotta University College of Medicine, Houston, Texas. 1962-64: Advanced Research Fellow of the American Heart Association. 1963-69: Co-Director of the Baylor-Rice Artificial Heart Program shared with Michael E. DeBakey and C. William Hall. Houston, Texas. 1964-71: Assistant Professor of Surgery, Baylor University College of Medicine, Chairman of the Department: Dr. Michael E. DeBakey, Houston, Texas. 1970-71: Director of Surgical Research, Texas Heart Institute, Chief of Cardiovascular Service Denton A. Cooley, Houston, Texas. 1971-74: Surgeon-in-Chief, Carlos Durand Public Hospital, Buenos Aires, Argentina. 1971-90: Surgeon-in-Chief, Service of Cardiovascular Surgery, Italian Hospital of Buenos Aires, Argentina. 1973-74: Secretary of State for Public Health, Argentina.
Human artificial chromosome artificial chromosome vectors. The first is to create a small minichromosome by altering a natural human chromosome. This is accomplished by truncating the natural chromosome, followed by the introduction of unique genetic material via the Cre-Lox system of recombination. The second method involves the literal creation of a novel chromosome "de novo". Progress regarding "de novo" HAC formation has been limited, as many large genomic fragments will not successfully integrate into "de novo" vectors. Another factor limiting "de novo" vector formation is limited knowledge of what elements are required for construction, specifically centromeric sequences. A 2009 study has shown additional