Rosetta Stone decree Rosetta Stone decree The Decree of Memphis (Ptolemy V) is the third Memphis decree, the first being for his grandfather Ptolemy III (Decree of Canopus), and the second being The Raphia Decree (Ptolemy IV). The Decree for Ptolemy V is the text recorded on the Rosetta Stone (issued at Memphis in 196 BC) in the Egyptian hieroglyphs, Demotic (Egyptian) script, and Greek. The Hellenistic Ptolemaic dynasty, which ruled Egypt from 305 BC to 30 BC, issued a series of decrees over the course of their reign. The Rosetta Stone is the best known example. After six lines of preview on
Rosetta@home design novel homing endonuclease proteins, which could eradicate "Anopheles gambiae" or otherwise render the mosquito unable to transmit malaria. Being able to model and alter protein–DNA interactions specifically, like those of homing endonucleases, gives computational protein design methods like Rosetta an important role in gene therapy (which includes possible cancer treatments). Originally introduced by the Baker laboratory in 1998 as an "ab initio" approach to structure prediction, Rosetta has since branched into several development streams and distinct services. The Rosetta platform derives its name from the Rosetta Stone, as it attempts to decipher the structural "meaning" of proteins' amino acid