Domingo Liotta shortly thereafter. 1962 (May): Prolonged assisted circulation during and after cardiac and aortic surgery. Prolonged partial left ventricular bypass by means of intracorporeal circulation. It was selected as Finalist for the Young Investigators´ Contest Award (Denver) of the American College of Cardiology. 1964: Annual Award, Southwestern Surgical Society, USA. Shared with C. William Hall and Michael E. DeBakey.1968: Golden Eagle Award, Council of International Nontheatrical Events, USA, shared with Denton A. Cooley, Robert Bloodwell, and Grady Hallman. 1969: Award of Merit, American Medical Association shared with Denton A. Cooley, MD. 1969: Decoration of the Institute of Spanish Culture, Madrid, Spain.
Human artificial chromosome artificial chromosome vectors. The first is to create a small minichromosome by altering a natural human chromosome. This is accomplished by truncating the natural chromosome, followed by the introduction of unique genetic material via the Cre-Lox system of recombination. The second method involves the literal creation of a novel chromosome "de novo". Progress regarding "de novo" HAC formation has been limited, as many large genomic fragments will not successfully integrate into "de novo" vectors. Another factor limiting "de novo" vector formation is limited knowledge of what elements are required for construction, specifically centromeric sequences. A 2009 study has shown additional