Cord lining Cord lining Cord lining, cord tissue, or umbilical cord lining membrane, is the outermost layer of the umbilical cord. As the umbilical cord itself is an extension of the placenta, the umbilical cord lining membrane is an extension of the amniotic membrane covering the placenta. The umbilical cord lining membrane comprises two layers: the amniotic (or epithelial) layer and the sub-amniotic (or mesenchymal) layer. The umbilical cord lining membrane is a rich source of two strains of stem cells: epithelial stem cells (from the amniotic layer) and mesenchymal stem cells (from the sub-amniotic layer). Discovered by Singapore based CellResearch Corp
Umbilical cord prolapse to congenital anomalies or prematurity, however. It is considered an emergency. The first sign of umbilical cord prolapse is usually a sudden decrease in fetal heart rate that is severe and does not immediately resolve. On a fetal heart tracing, this would usually look like moderate to severe variable decelerations. Occasionally, the cord can be seen or felt on vaginal examination, particularly with overt cord prolapse. Risk factors that are associated with umbilical cord prolapse tend to make it difficult for the fetus from appropriately engaging and filling the maternal pelvis or are related to abnormalities of the umbilical cord.