Provence wine Cassis specializing in white wine production. The Côtes de Provence is the largest AOC followed by the Coteaux d'Aix-en-Provence. The Bandol region near Toulon is one of the more internationally recognized Provençal wine regions. The exact time when viticulture began in Provence is difficult to calculate. Early inhabitants may have used indigenous vines to produce wine before the Phocaean Greeks settled Massalia in 600 BC. Archaeological evidence, in the form of amphora fragments, indicate that the Greeks were producing wine in the region soon after they settled. By the time the Romans reached the area in 125 BC, the wine
Ancient Greece and wine digestive aid. The Greeks were also aware of some negative health effects, especially those arising from the consumption of wine beyond moderation. Athenaeus made frequent mention of wine's ability to induce hangover and suggested various remedies for it. The poet Eubulus noted that three bowls ("kylikes") were the ideal amount of wine to consume. The quantity of three bowls to represent moderation is a recurring theme throughout Greek writing (today, the standard 750 ml bottle contains roughly three to six glasses of wine, depending on serving size). In his c. 375 BC play "Semele or Dionysus", Eubulus has Dionysus say: