Artificial heart of instances of bleeding, and asked several times to be allowed to die. On April 4, 1969, Domingo Liotta and Denton A. Cooley replaced a dying man's heart with a mechanical heart inside the chest at The Texas Heart Institute in Houston as a bridge for a transplant. The man woke up and began to recover. After 64 hours, the pneumatic-powered artificial heart was removed and replaced by a donor heart. However thirty-two hours after transplantation, the man died of what was later proved to be an acute pulmonary infection, extended to both lungs, caused by fungi, most likely caused
Artificial bone fractured bone. However, if damage to bone is caused by a disease or severe injury, it becomes difficult for the body to repair itself. When the human body is unable to regenerate the lost bone tissue, surgeons come in and replace the missing bone using autografts, allografts, and synthetic grafts (artificial bone). When compare artificial bone to autograft and allograft, it is less invasive and more biocompatible since it avoids the risk of unknown viral infections. When designing implanted biomaterials, key criteria are biocompatibility, osteoconductivity, high porosity and biomechanics compatibility. Artificial bone was initially made of materials like metals and