Domingo Liotta University College of Medicine, Houston, Texas. 1962-64: Advanced Research Fellow of the American Heart Association. 1963-69: Co-Director of the Baylor-Rice Artificial Heart Program shared with Michael E. DeBakey and C. William Hall. Houston, Texas. 1964-71: Assistant Professor of Surgery, Baylor University College of Medicine, Chairman of the Department: Dr. Michael E. DeBakey, Houston, Texas. 1970-71: Director of Surgical Research, Texas Heart Institute, Chief of Cardiovascular Service Denton A. Cooley, Houston, Texas. 1971-74: Surgeon-in-Chief, Carlos Durand Public Hospital, Buenos Aires, Argentina. 1971-90: Surgeon-in-Chief, Service of Cardiovascular Surgery, Italian Hospital of Buenos Aires, Argentina. 1973-74: Secretary of State for Public Health, Argentina.
Artificial cell cells have been proposed as a non-viral vector by which genetically modified non-autologous cells are encapsulated and implanted to deliver recombinant proteins "in vivo". This type of immuno-isolation has been proven efficient in mice through delivery of artificial cells containing mouse growth hormone which rescued a growth-retardation in mutant mice. A few strategies have advanced to human clinical trials for the treatment of pancreatic cancer, lateral sclerosis and pain control. The first clinical use of artificial cells was in hemoperfusion by the encapsulation of activated charcoal. Activated charcoal has the capability of adsorbing many large molecules and has for a