Nuclear binding energy Only under conditions of extreme pressure and temperature (for example, within the core of a star), can such a process take place. There are around 94 naturally occurring elements on earth. The atoms of each element have a nucleus containing a specific number of protons (always the same number for a given element), and some number of neutrons, which is often roughly a similar number. Two atoms of the same element having different numbers of neutrons are known as isotopes of the element. Different isotopes may have different properties - for example one might be stable and another might be
Hydrogen–deuterium exchange can be measured at atomic resolution quantitatively by neutron crystallography, and in real time if exchange is conducted during the diffraction experiment. High intensity neutron beams are generally generated by spallation at linac particle accelerators such as the Spallation Neutron Source. Neutrons diffract crystals similarly to X-rays and can be used for structural determination. Hydrogen atoms, with between one and zero electrons in a biological setting, diffract X-rays poorly and are effectively invisible under normal experimental conditions. Neutrons scatter from atomic nuclei, and are therefore capable of detecting hydrogen and deuterium atoms. Hydrogen atoms are routinely replaced with deuterium, which