Digitalis digitalis. As a result of increased contractility, stroke volume is increased. Ultimately, digitalis increases cardiac output (Cardiac Output=Stroke Volume x Heart Rate). This is the mechanism that makes this drug a popular treatment for congestive heart failure, which is characterized by low cardiac output. Digitalis also has a vagal effect on the parasympathetic nervous system, and as such is used in re-entrant cardiac arrhythmias and to slow the ventricular rate during atrial fibrillation. The dependence on the vagal effect means digitalis is not effective when a patient has a high sympathetic nervous system drive, which is the case with acutely
Derive (computer algebra system) Derive (computer algebra system) Derive was a computer algebra system, developed as a successor to muMATH by the Soft Warehouse in Honolulu, Hawaii, now owned by Texas Instruments. Derive was implemented in , also by Soft Warehouse. The first release was in 1988 for DOS. It was discontinued on June 29, 2007 in favor of the TI-Nspire CAS. The last and final version is Derive 6.1 for Windows. Since Derive required comparably little memory, it was suitable for use on older and smaller machines. It was available for the DOS and Windows platforms and was used also in TI pocket