Digitalis digitalis. As a result of increased contractility, stroke volume is increased. Ultimately, digitalis increases cardiac output (Cardiac Output=Stroke Volume x Heart Rate). This is the mechanism that makes this drug a popular treatment for congestive heart failure, which is characterized by low cardiac output. Digitalis also has a vagal effect on the parasympathetic nervous system, and as such is used in re-entrant cardiac arrhythmias and to slow the ventricular rate during atrial fibrillation. The dependence on the vagal effect means digitalis is not effective when a patient has a high sympathetic nervous system drive, which is the case with acutely
How We Do (Party) How We Do (Party) "How We Do (Party)" is a song by British singer Rita Ora, from her debut studio album, "Ora". It was released as the lead single from the album in the United States, Canada, Australia and New Zealand on 20 March 2012. Upon its release, "How We Do (Party)" peaked inside the top-ten in Australia and New Zealand. It was released as the album's second single in Ireland on 10 August 2012 and in the United Kingdom on 12 August 2012, and reached number-one in both regions. "How We Do (Party)" is a pop and R&B song.