X-Men: Reign of Apocalypse controlled by Apocalypse with backgrounds that stay true to the X-Men comics. X-mansion, Blackbird, Genosha and other familiar locations are present. The playable X-Men roster consists of: Wolverine, Cyclops, Storm, and Rogue. Each character has a different super power that give them a unique playstyle. Boss enemies include classic villains from the comics such as Blob and Magneto. X-Men from the 616 Marvel Universe, such as Colossus and Nightcrawler are also allies of Apocalypse in this alternate universe and must be defeated. "X-Men: Reign of Apocalypse" is a side-scrolling action beat 'em up with 12 distinct levels. Each level has
Cerebro's X-Men winged Rapture, the elemental Crux, the superstrong Landslide, the metallic Mercury, and the destructive Chaos formed his perfect team. The new "X-Men" attacked the real X-Men, and captured Shadowcat. She was taken to Xavier, who told her he was dying of a computer virus given to him by Bastion. Xavier asked her to reconfigure a computer system to help him. Shadowcat quickly fixed the computer, and Xavier seemed to be "cured", then he ordered his "X-Men" to place her in cryogenic storage, so her DNA would be preserved for future study. He told her that all obsolete mutants must be