Digitalis purpurea pharmacological forms, extracts of this plant did not frequently cause intoxication because they induced nausea and vomiting within minutes of ingestion, preventing the patient from consuming more. The main toxins in "Digitalis" spp. are the two chemically similar cardiac glycosides: digitoxin and digoxin. Like other cardiac glycosides, these toxins exert their effects by inhibiting the ATPase activity of a complex of transmembrane proteins that form the sodium potassium ATPase pump, (Na/K-ATPase). Inhibition of the Na/K-ATPase in turn causes a rise not only in intracellular Na, but also in calcium, which in turn results in increased force of myocardial muscle contractions.
(We Do It) Primo (We Do It) Primo "(We Do It) Primo" is a song by American recording artist Colette Carr. The song was written by Carr, and produced by Frankmusik. "(We Do It) Primo" was released on May 11, 2011 by Interscope as the first single from Carr's debut album "Skitszo". The song was written about just having fun and a good time. "(We Do It) Primo" is musically known as a "summer anthem" by many critics. It samples Keane’s song "Somewhere Only We Know". The song garnered mainly positive reviews from music critics. Many critics called it a "fun", "terrific" and "a