Euston Road the 1960s to cater for the increasing demands of motor traffic, and the Euston Tower was built around that time. The road contains several significant buildings including the Wellcome Library, the British Library and the St. Pancras Renaissance London Hotel. The road starts as a continuation of the A501, a major road through Central London, at its junction with Marylebone Road and Great Portland Street. It meets the northern end of Tottenham Court Road at a large junction where there is an underpass, and ends at King's Cross with Gray's Inn Road. The road ahead to Islington is Pentonville Road.
Euston Road and providing a pedestrian crossing and removing the gyratory system connecting the Tottenham Court Road and Gower Street. The scheme was approved by the Mayor of London, Ken Livingstone as "the start of changing the Marylebone to Euston road from a highway into a series of linked public spaces." The pedestrian crossing opened in March 2010. Livingstone's successor, Boris Johnson, favours keeping the Euston Road underpass and declared it to be a good place to test his nerves when cycling around London. In 2015, Transport for London announced its intention to close one lane in each direction on Euston Road