Wishin' and Hopin' (Grey's Anatomy) for their new clinic, Dr. Richard Webber (James Pickens, Jr.) dealing with the repercussions of his upcoming retirement, and Dr. George O'Malley (T.R. Knight) facing negative response from colleagues on his unexpected marriage to Dr. Callie Torres (Sara Ramirez). Although the episode was fictionally set in Seattle, filming occurred in Los Angeles, California. Burton reprised her role as Dr. Ellis Grey in a guest star capacity, in addition to Sarah Utterback, who portrayed Olivia Harper. The title of the episode refers to the song "Wishin' and Hopin'", by British pop musician Dusty Springfield. The episode received mixed to favorable reviews,
Dusty Springfield began in 1963 with the upbeat pop hit, "I Only Want to Be with You". Among the hits that followed were "Wishin' and Hopin' " (1964), "I Just Don't Know What to Do with Myself" (1964), "You Don't Have to Say You Love Me" (1966), and "Son of a Preacher Man" (1968). As a fan of US soul music, she brought many little-known soul singers to the attention of a wider UK record-buying audience by hosting the first national TV performance of many top-selling Motown artists beginning in 1965. Partly owing to these efforts, a year later she eventually became