Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
The Way We Do It is highly regarded as a masterpiece by the band. It is sung mostly in English and string parts based on Raga Hamsadhvani. From iTunes. The Way We Do It The Way We Do It is the second studio album of Colonial Cousins, an Indian duo composed of singer Hariharan and singer-composer Lesle Lewis. It was released on November 19, 1998 under the label Sony BMG. The first Colonial Cousins album was a tour de force. On November 19, 1998, their second album, a sophomore effort, "The Way We Do It", was a continuation of and a departure from that first