Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
Where Do We Go from Here (Filter song) song was made by The X-Ecutioners which gained extensive club play. A music video was also produced for the song. It received moderate airplay upon release. Like many of the band's singles, the single version of "Where Do We Go From Here" (the one used for radio and the music video) is much shorter than the album version. The album version extends the pre-choruses and bridge mostly. Where Do We Go from Here (Filter song) "Where Do We Go from Here" is a song by American industrial rock band Filter for their third studio album, The Amalgamut. The song was