Digitalis digitalis. As a result of increased contractility, stroke volume is increased. Ultimately, digitalis increases cardiac output (Cardiac Output=Stroke Volume x Heart Rate). This is the mechanism that makes this drug a popular treatment for congestive heart failure, which is characterized by low cardiac output. Digitalis also has a vagal effect on the parasympathetic nervous system, and as such is used in re-entrant cardiac arrhythmias and to slow the ventricular rate during atrial fibrillation. The dependence on the vagal effect means digitalis is not effective when a patient has a high sympathetic nervous system drive, which is the case with acutely
Where Do We Go from Here? (1945 film) Where Do We Go from Here? (1945 film) Where Do We Go from Here (1945) Technicolor is a romantic musical comedy-fantasy film produced by Twentieth Century-Fox, and starring Fred MacMurray, Joan Leslie, June Haver, Gene Sheldon, Anthony Quinn and Fortunio Bonanova. Joan Leslie's singing voice was dubbed by Sally Sweetland. The score was composed by Kurt Weill with lyrics by Ira Gershwin. Gregory Ratoff directed and Morrie Ryskind wrote the screenplay from a story by Sig Herzig and Ryskind. The film is notable as Weill's only musical written directly for the screen and for its anachronistic blend of history and