Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
Things We Do at Night (Live from Texas) Up/Down Records and distributed by Megaforce Records was released to online digital retail outlets as well as on CD, DVD and Blu-ray formats on November 20, 2015. The album takes its name from the song "Things We Do At Night" from the "Sway" album, which the band played to close their concerts on each night of the Sway tour. The album debuted at #175 on the "Billboard" 200, #12 on the Alternative Albums chart, #20 on the Rock Albums Chart, and #9 on the Independent Albums Chart. Things We Do at Night (Live from Texas) Things We Do At Night