Digitalis purpurea pharmacological forms, extracts of this plant did not frequently cause intoxication because they induced nausea and vomiting within minutes of ingestion, preventing the patient from consuming more. The main toxins in "Digitalis" spp. are the two chemically similar cardiac glycosides: digitoxin and digoxin. Like other cardiac glycosides, these toxins exert their effects by inhibiting the ATPase activity of a complex of transmembrane proteins that form the sodium potassium ATPase pump, (Na/K-ATPase). Inhibition of the Na/K-ATPase in turn causes a rise not only in intracellular Na, but also in calcium, which in turn results in increased force of myocardial muscle contractions.
How We Do (Party) How We Do (Party) "How We Do (Party)" is a song by British singer Rita Ora, from her debut studio album, "Ora". It was released as the lead single from the album in the United States, Canada, Australia and New Zealand on 20 March 2012. Upon its release, "How We Do (Party)" peaked inside the top-ten in Australia and New Zealand. It was released as the album's second single in Ireland on 10 August 2012 and in the United Kingdom on 12 August 2012, and reached number-one in both regions. "How We Do (Party)" is a pop and R&B song.