Digitalis purpurea pharmacological forms, extracts of this plant did not frequently cause intoxication because they induced nausea and vomiting within minutes of ingestion, preventing the patient from consuming more. The main toxins in "Digitalis" spp. are the two chemically similar cardiac glycosides: digitoxin and digoxin. Like other cardiac glycosides, these toxins exert their effects by inhibiting the ATPase activity of a complex of transmembrane proteins that form the sodium potassium ATPase pump, (Na/K-ATPase). Inhibition of the Na/K-ATPase in turn causes a rise not only in intracellular Na, but also in calcium, which in turn results in increased force of myocardial muscle contractions.
Where Do We Come From? What Are We? Where Are We Going? Where Do We Come From? What Are We? Where Are We Going? Where Do We Come From? What Are We? Where Are We Going? is a painting by French artist Paul Gauguin. Gauguin inscribed the original French title in the upper left corner: D'où Venons Nous / Que Sommes Nous / Où Allons Nous. The inscription the artist wrote on his canvas has no question mark, no dash, and all words are capitalized. In the upper right corner he signed and dated the painting: "P. Gauguin / 1897". The painting was created in Tahiti, and is in the Museum of