Digitalis purpurea" extract containing cardiac glycosides for the treatment of heart conditions was first described in the English-speaking medical literature by William Withering, in 1785, which is considered the beginning of modern therapeutics. It is used to increase cardiac contractility (it is a positive inotrope) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular (and often fast) atrial fibrillation. Digitalis is hence often prescribed for patients in atrial fibrillation, especially if they have been diagnosed with congestive heart failure. Digoxin was approved for heart failure in 1998 under current regulations by the Food and Drug Administration
Where Do We Go from Here? (2015 film) Film Awards. Where Do We Go from Here? (2015 film) Where Do We Go from Here? is a Scottish comedy feature film by John McPhail. The film centres on James (Tyler Collins) a young man who takes on the role of a janitor of a care home when his Grandad is forced into social care. It is the first feature to be directed by John McPhail. When Jen starts her new Job as a nurse at the 'Easy Love Care Home, she is surprised to find James, a 25-year-old man living and working in the building. James and his three,