Digitalis digitalis. As a result of increased contractility, stroke volume is increased. Ultimately, digitalis increases cardiac output (Cardiac Output=Stroke Volume x Heart Rate). This is the mechanism that makes this drug a popular treatment for congestive heart failure, which is characterized by low cardiac output. Digitalis also has a vagal effect on the parasympathetic nervous system, and as such is used in re-entrant cardiac arrhythmias and to slow the ventricular rate during atrial fibrillation. The dependence on the vagal effect means digitalis is not effective when a patient has a high sympathetic nervous system drive, which is the case with acutely
We Do What We Want decision to write a heavier and more hardcore album than they had done in the past. Commenting on the band's evolved sound, bassist/vocalist Toby Morrell said, "I don't think we ever thought we'd get as heavy as we are now, but I'm glad we have." Though Shelton was not an active member of Emery during the writing process for "We Do What We Want", he wrote the final track on the standard edition titled "Fix Me," and the song "Crumbling" from the deluxe edition. Regarding the album's lyrical themes, vocalist Toby Morrell stated: In the month of March 2011, an