Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
You Know How We Do It You Know How We Do It "You Know How We Do It" is the second single from Ice Cube's fourth studio album, "Lethal Injection." It was released as a 12" single on February 2, 1994. A G-funk hit which has the same kind of mood and feeling from "The Predator", it samples "The Show Is Over" by Evelyn "Champagne" King and uses an interpretation of "Summer Madness" by Kool & the Gang. Eventually Mariah Carey sampled "You Know How We Do It" in her song "Irresistible (West Side Connection)" from her 2002 album "Charmbracelet". At the time of the album's