Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
We Do What We Want decision to write a heavier and more hardcore album than they had done in the past. Commenting on the band's evolved sound, bassist/vocalist Toby Morrell said, "I don't think we ever thought we'd get as heavy as we are now, but I'm glad we have." Though Shelton was not an active member of Emery during the writing process for "We Do What We Want", he wrote the final track on the standard edition titled "Fix Me," and the song "Crumbling" from the deluxe edition. Regarding the album's lyrical themes, vocalist Toby Morrell stated: In the month of March 2011, an