Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
You Press the Button, We Do the Rest Thanks to the "We Do the Rest" advertising campaign, the Kodak camera became wildly popular and Eastman and his Kodak company revolutionized the photography business in the United States and in the world. Thanks to the income generated from advertising this camera, Eastman Kodak was able to dominate competition for years and lead the way in photography innovations for years. You Press the Button, We Do the Rest "You Press the Button, We Do the Rest" was an advertising slogan coined by George Eastman, the founder of Kodak, in 1888. Eastman believed in making photography available to the world, and