Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
We Do (film) We Do (film) We Do is an award-winning 56 minute documentary film about marriage equality, produced and directed by independent filmmaker Rebecca Rice. "We Do" reveals the stories of three LGBT couples, their journeys for legal recognition of their relationships and the impact that the pursuit of marriage equality has had on their lives before and after the Supreme Court ruling on June 26, 2015. The film features an introduction by LGBT activist and pastor Jim Mitulski, former pastor at Cathedral of Hope (Dallas) who provides the backstory on same-sex unions. "We Do" then tells the stories of Leta and