Digitalis purpurea" extract containing cardiac glycosides for the treatment of heart conditions was first described in the English-speaking medical literature by William Withering, in 1785, which is considered the beginning of modern therapeutics. It is used to increase cardiac contractility (it is a positive inotrope) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular (and often fast) atrial fibrillation. Digitalis is hence often prescribed for patients in atrial fibrillation, especially if they have been diagnosed with congestive heart failure. Digoxin was approved for heart failure in 1998 under current regulations by the Food and Drug Administration
Where Do We Go from Here (album) Where Do We Go from Here (album) Where Do We Go from Here is the third album by Christian metal band Pillar. The song "Bring Me Down" was featured on the 2005 Major League Baseball video game, MLB 2006, as well as the offroad racing game MX vs. ATV Unleashed. The song "Frontline", along with "Bring Me Down", reached No. 1 on the Christian rock charts. The album debuted at No. 74 on the "Billboard" 200. "Where Do We Go from Here" garnered generally positive reception from seven music critics. At "CCM Magazine", David Jenison graded the album an A,