Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
We Do What We Want We Do What We Want We Do What We Want is the fifth studio album by the American rock band Emery. The album was released on March 29, 2011 through Tooth & Nail Records and Solid State Records. Shortly after announcing the release of "We Do What We Want", founding bassist Devin Shelton announced he would be taking an indefinite hiatus from Emery. Emery was in the process of working on more stripped-down acoustic album when guitarist/vocalist Devin Shelton decided to take an indefinite leave of absence from the group. After his departure, the remaining four members made the conscious