Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
Where Do We Go from Here? (Chicago song) Where Do We Go from Here? (Chicago song) "Where Do We Go from Here?" is a song from the American rock band Chicago's second studio album, "Chicago" (1970). It was released as the B-side to the single "25 or 6 to 4", one of the leading songs off of the record. With that single, it went to number four on the Pop Singles chart in June 1970. The song was also the very first musical composition from bassist Peter Cetera, who was by this time contributing more than on the debut album released the year before. The song deals with