Digitalis purpurea" extract containing cardiac glycosides for the treatment of heart conditions was first described in the English-speaking medical literature by William Withering, in 1785, which is considered the beginning of modern therapeutics. It is used to increase cardiac contractility (it is a positive inotrope) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular (and often fast) atrial fibrillation. Digitalis is hence often prescribed for patients in atrial fibrillation, especially if they have been diagnosed with congestive heart failure. Digoxin was approved for heart failure in 1998 under current regulations by the Food and Drug Administration
How We Do (Party) How We Do (Party) "How We Do (Party)" is a song by British singer Rita Ora, from her debut studio album, "Ora". It was released as the lead single from the album in the United States, Canada, Australia and New Zealand on 20 March 2012. Upon its release, "How We Do (Party)" peaked inside the top-ten in Australia and New Zealand. It was released as the album's second single in Ireland on 10 August 2012 and in the United Kingdom on 12 August 2012, and reached number-one in both regions. "How We Do (Party)" is a pop and R&B song.