Digitalis lactone and a triple-repeating sugar called a glycoside. Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility. Under normal physiological conditions, the cytoplasmic calcium used in
Where Do We Go Where Do We Go "Where Do We Go" is a song by British recording artist, Jay Sean, taken from his mixtape album,"The Mistress" and is the mixtape's lead single. The song was produced by OFM production team J-Remy and Bobby Bass. Jay Sean asks "Where Do We Go" on the first release from his mixtape The Mistress featuring acoustic renditions of original songs and his spin on some beloved classics. The Cash Money crooner tries to put back the pieces of a broken relationship on the stripped-down ballad, which is also accompanied by a video of him in the studio,