X-Men: Pryde of the X-Men pilot effectively marked the end of the Marvel animated universe created by DePatie-Freleng Enterprises/Marvel Productions, which began with "Fantastic Four" (1978) and continued with "Spider-Woman" (1979), "Spider-Man" (1981), "Spider-Man and His Amazing Friends" (1981) and "The Incredible Hulk" (1982). The X-Men themselves had previously guest starred in several episodes of "Spider-Man and His Amazing Friends", although that particular series isn't necessarily in the same continuity as "Pryde of the X-Men". Narrated by X-Men co-creator Stan Lee, "Pryde of the X-Men" stars Professor X and the X-Men who were known as Cyclops, Storm, Nightcrawler, Colossus, Wolverine, Kitty Pryde, and Dazzler saving
X-Men presented in the comics serve as allegory to modern issues in the real world, such as Lydia Nance suggesting mass mutant deportation. The X-Men exist in the Marvel Universe along with other characters featured in Marvel Comics series. They often meet characters from other series, and the global nature of the mutant concept means the scale of stories can be highly varied. The X-Men's enemies range from mutant thieves to galactic threats. Historically, the X-Men have been based in the Xavier Institute, in the town of Salem, located in Westchester County, New York, and are often portrayed as a family.