X-Men: Reign of Apocalypse controlled by Apocalypse with backgrounds that stay true to the X-Men comics. X-mansion, Blackbird, Genosha and other familiar locations are present. The playable X-Men roster consists of: Wolverine, Cyclops, Storm, and Rogue. Each character has a different super power that give them a unique playstyle. Boss enemies include classic villains from the comics such as Blob and Magneto. X-Men from the 616 Marvel Universe, such as Colossus and Nightcrawler are also allies of Apocalypse in this alternate universe and must be defeated. "X-Men: Reign of Apocalypse" is a side-scrolling action beat 'em up with 12 distinct levels. Each level has
X-Men Legends II: Rise of Apocalypse characters return from "X-Men Legends", and select members of the Brotherhood of Mutants are also playable. Some non-playable X-Men and Brotherhood characters appear during levels. In some instances dialogue throughout the game can be character-to-character specific, depending on the player character's alignment and relationship with the non-player character. "X-Men Legends II: Rise of Apocalypse" was announced on October 21, 2004, exactly one month after the release of "X-Men Legends". It was shown at Electronic Entertainment Expo (E3) and San Diego Comic-Con in 2005. It was first released in North America on September 20, 2005 for the Gamecube, PlayStation 2, Xbox