IPod charge the device) in an attempt to reduce cost and form factor. As of the second-generation iPod Touch and the fourth-generation iPod Nano, FireWire charging ability has been removed. The second-, third-, and fourth-generation iPod Shuffle uses a single 3.5 mm minijack phone connector which acts as both a headphone jack or a USB data and charging port for the dock/cable. The dock connector also allowed the iPod to connect to accessories, which often supplement the iPod's music, video, and photo playback. Apple sells a few accessories, such as the now-discontinued iPod Hi-Fi, but most are manufactured by third parties
JUNQ and IPOD IPOD may serve not only as a sequestration site, but also as a functional compartment. The IPOD is a non- membrane bound cellular site, which in yeast is located by the vacuole. FRAP and FLIP assays revealed that proteins in the IPOD are tightly packed, in-soluble and don't exchange with the cytosol. Amyloidogenic proteins, such as the Huntingtin protein, are the IPOD's substrates. Misfolded proteins must be non-ubiquitinated to be sorted to the IPOD. Ubiquitination of an otherwise IPOD substrate, such as the RNQ1 fungal prion, will result in its sequestration in the JUNQ inclusion. Upon accumulation of misfolded proteins,