IPod Nano game was dropped and replaced with a Maze game which makes use of the iPod's accelerometer similarly to such games on the iPhone and iPod Touch. The fourth generation dropped support for charging via FireWire. "This change means that any dock accessories that use the dock connector's FireWire pins to send power—many older speakers and car chargers, for example—will not charge the fourth-generation iPod Nano." At Apple's September 9, 2009 event, a fifth generation iPod Nano was unveiled with reduced prices on the larger model (at the time of release, the 8GB was priced at $149 and the 16GB at
JUNQ and IPOD the late onset of neurodegenerative diseases. In such diseases (e.g. Huntington's disease), a mutated protein misfolds and becomes toxic to the cellular environment by various ways such as denaturating cytosolic proteins. Incompetent of degrading those toxic species, the cell must isolate them to avoid their hazardous interaction with the cellular proteome. The IPOD was shown to be the sub-cellular site to which toxic amyloidogenic proteins are sequestered to, hereby serving as a protective quality control compartment. In addition, it was suggested by the Lindquist group, that the IPOD is the site where yeast prions undergo a maturation process. Thus, the