IPod Touch on March 6, 2008, at an Apple Town Hall meeting. The iOS SDK allows making applications for the iPhone and iPod Touch after paying a fee to join the development team. The developer can then set the price for the applications they develop and will receive 70% of money earned. Apple retains 30% of the sale price with no minimum fixed fee. Like all of Apple's iOS devices, the iPod Touch is a tightly controlled or closed platform. Modifying or replacing the operating system voids the device warranty, communication between apps is limited and controlled, and Apple is the only
JUNQ and IPOD and processing of different kinds of misfolded proteins (e.g. ubiquitinated vs. non-ubiquitinated proteins). Segregation of toxic protein aggregates into JUNQ and IPOD inclusion bodies is a means by which mammalian cells can be rejuvenated through asymmetric division. Thus, the discovery of JUNQ and IPOD provided a new striking perspective of how cells manage misfolded aggregated proteins and gave convincing proof that protein aggregation is a non-random, well regulated and controlled cellular process. Furthermore, the discovery of JUNQ and IPOD suggested that in addition to temporal quality control (i.e. time dependent administration of damaged proteins) cells exploit homeostasis spatially: If degradation