IPod Nano had the same price point as the 5th generation device. A firmware update (version 1.1) for the Nano was released on February 28, 2011. The update added the ability to change songs or pause with a double click of the sleep/wake button. It also added the ability to turn the device off by holding the sleep/wake button. The user interface was also enhanced. On October 4, 2011, the iPod Nano 1.2 update was unveiled at the Apple "Let's Talk iPhone" event at the Town Hall, 4 Infinite Loop. This update added the option to increase or decrease the size of
JUNQ and IPOD that protein aggregation may actually be a tightly regulated, organized process, by which the cell protects itself from toxic proteins by sequestration to inclusion bodies. In 2008, Daniel Kaganovich showed that eukaryotic cells sort misfolded proteins into two distinct inclusion bodies in a well-managed cellular process: JUNQ and IPOD are evolutionarily conserved, and are found in specific and defined cellular sites. Delivery of misfolded, aggregated proteins to JUNQ and IPOD require an intact cytoskeleton and specific cellular quality control components, such as Heat Shock Proteins (HSPs). The partition into the two distinct inclusion bodies is due to the different handling