IPhone 4 models. In fall 2010, pentalobe screws started to replace the Philips screws used in post-repair units in the US and in production units in Japan. The iPhone 4 shipped with iOS 4, which was the newest version of Apple's iOS mobile operating system at the time. iOS 4 introduced a multitasking system, allowing apps to remain "suspended" in memory, perform certain operations in the background, and allowing users to switch between apps using an on-screen menu. It also introduced FaceTime, which allows users to perform video calls between other iPhone, iPad, iPod Touch, and OS X users. The iPhone 4
JUNQ and IPOD that protein aggregation may actually be a tightly regulated, organized process, by which the cell protects itself from toxic proteins by sequestration to inclusion bodies. In 2008, Daniel Kaganovich showed that eukaryotic cells sort misfolded proteins into two distinct inclusion bodies in a well-managed cellular process: JUNQ and IPOD are evolutionarily conserved, and are found in specific and defined cellular sites. Delivery of misfolded, aggregated proteins to JUNQ and IPOD require an intact cytoskeleton and specific cellular quality control components, such as Heat Shock Proteins (HSPs). The partition into the two distinct inclusion bodies is due to the different handling