IPod Touch on March 6, 2008, at an Apple Town Hall meeting. The iOS SDK allows making applications for the iPhone and iPod Touch after paying a fee to join the development team. The developer can then set the price for the applications they develop and will receive 70% of money earned. Apple retains 30% of the sale price with no minimum fixed fee. Like all of Apple's iOS devices, the iPod Touch is a tightly controlled or closed platform. Modifying or replacing the operating system voids the device warranty, communication between apps is limited and controlled, and Apple is the only
JUNQ and IPOD IPOD may serve not only as a sequestration site, but also as a functional compartment. The IPOD is a non- membrane bound cellular site, which in yeast is located by the vacuole. FRAP and FLIP assays revealed that proteins in the IPOD are tightly packed, in-soluble and don't exchange with the cytosol. Amyloidogenic proteins, such as the Huntingtin protein, are the IPOD's substrates. Misfolded proteins must be non-ubiquitinated to be sorted to the IPOD. Ubiquitination of an otherwise IPOD substrate, such as the RNQ1 fungal prion, will result in its sequestration in the JUNQ inclusion. Upon accumulation of misfolded proteins,