IPod Touch (5th generation) iOS being iOS 6, iOS 7, iOS 8 and iOS 9. iOS 9 is said by Apple to feature performance improvements that may help the aging device function more smoothly. Other A5-based devices will also support iOS 9 including the iPad 2 (6 major iOS versions), the iPhone 4S (5 major iOS versions) and the iPad Mini (4 major iOS versions). iOS 9.3.5 is the last update that supports the iPod Touch 5th generation as it did not receive iOS 10 along with the iPhone 4S, iPad 2 and 3, and iPad Mini 1st generation due to hardware limitations. The
JUNQ and IPOD and processing of different kinds of misfolded proteins (e.g. ubiquitinated vs. non-ubiquitinated proteins). Segregation of toxic protein aggregates into JUNQ and IPOD inclusion bodies is a means by which mammalian cells can be rejuvenated through asymmetric division. Thus, the discovery of JUNQ and IPOD provided a new striking perspective of how cells manage misfolded aggregated proteins and gave convincing proof that protein aggregation is a non-random, well regulated and controlled cellular process. Furthermore, the discovery of JUNQ and IPOD suggested that in addition to temporal quality control (i.e. time dependent administration of damaged proteins) cells exploit homeostasis spatially: If degradation