IPhone Dev Team IPhone Dev Team The iPhone Dev Team was a group of engineers in the iOS (formerly "iPhone OS") community which had developed several tools to enable use of applications not authorized by Apple Inc on the iPhone, iPod Touch and iPad, and to enable use of the iPhone on GSM carriers not contracted by Apple. These applications provided owners with the ability to sidestep the limitations placed on the devices by the manufacturer, allowing for activities such as deep customization and easy international roaming. The group and their tools became emblematic for these activities, which are termed jailbreaking and SIM
JUNQ and IPOD IPOD may serve not only as a sequestration site, but also as a functional compartment. The IPOD is a non- membrane bound cellular site, which in yeast is located by the vacuole. FRAP and FLIP assays revealed that proteins in the IPOD are tightly packed, in-soluble and don't exchange with the cytosol. Amyloidogenic proteins, such as the Huntingtin protein, are the IPOD's substrates. Misfolded proteins must be non-ubiquitinated to be sorted to the IPOD. Ubiquitination of an otherwise IPOD substrate, such as the RNQ1 fungal prion, will result in its sequestration in the JUNQ inclusion. Upon accumulation of misfolded proteins,