IPhone pay any costs to release or distribute the application beyond the membership fee. The App Store was launched with the release of iOS 2.0, on July 11, 2008. The update was free for iPhone users; owners of older iPod Touches were required to pay US$10 for it. Once a developer has submitted an application to the App Store, Apple holds firm control over its distribution. Apple can halt the distribution of applications it deems inappropriate, for example, I Am Rich, a US$1000 program that simply demonstrated the wealth of its user. Apple has been criticized for banning third-party applications that
JUNQ and IPOD JUNQ and IPOD JUNQ and IPOD are types of cytosolic protein inclusion bodies in eukaryotes. Neurodegenerative diseases, such as Parkinson's, Alzheimer's, and Huntington's, are associated and correlated with protein aggregation and accumulation of misfolded proteins in inclusion bodies. For many years, protein aggregation was considered a random process by which misfolded proteins stick to each other to form inclusions (imagine a bundle of hairs haphazardly piling up in a corner of a room). Moreover, protein aggregates were thought to be toxic agents and the cause for neuronal dysfunction and death. However, recent studies, using advanced methods (i.e. fluorescence microscopy), show