IPhone of the iPhone have also garnered praise. The iPhone is one of the most widely used smartphones in the world, and its success has been credited with helping Apple become one of the world's most valuable publicly traded companies. Development of what was to become the iPhone began in 2004, when Apple started to gather a team of 1,000 employees (including Jonathan Ive, the designer behind the iMac and iPod) to work on the highly confidential "Project Purple." Apple CEO Steve Jobs steered the original focus away from a tablet (which Apple eventually revisited in the form of the iPad)
JUNQ and IPOD and processing of different kinds of misfolded proteins (e.g. ubiquitinated vs. non-ubiquitinated proteins). Segregation of toxic protein aggregates into JUNQ and IPOD inclusion bodies is a means by which mammalian cells can be rejuvenated through asymmetric division. Thus, the discovery of JUNQ and IPOD provided a new striking perspective of how cells manage misfolded aggregated proteins and gave convincing proof that protein aggregation is a non-random, well regulated and controlled cellular process. Furthermore, the discovery of JUNQ and IPOD suggested that in addition to temporal quality control (i.e. time dependent administration of damaged proteins) cells exploit homeostasis spatially: If degradation