IPhone OS 2 Apple II and Mac as one of the great revolutions in modern technology. It takes it beyond simple Phone + iPod, or even smartphone, and makes it the leading contender for the next great shift in computing." However, they criticized it for having stability issues and overall sluggishness. "Macworld" said, "The iPhone 2.0 software is full of the kind of refinements that you’d expect from a second-generation Apple product. The iPhone OS still isn’t perfect, and we wish Apple has addressed some lingering shortcomings, but it’s a welcome step-up for what was already arguably the best mobile platform on the
JUNQ and IPOD and processing of different kinds of misfolded proteins (e.g. ubiquitinated vs. non-ubiquitinated proteins). Segregation of toxic protein aggregates into JUNQ and IPOD inclusion bodies is a means by which mammalian cells can be rejuvenated through asymmetric division. Thus, the discovery of JUNQ and IPOD provided a new striking perspective of how cells manage misfolded aggregated proteins and gave convincing proof that protein aggregation is a non-random, well regulated and controlled cellular process. Furthermore, the discovery of JUNQ and IPOD suggested that in addition to temporal quality control (i.e. time dependent administration of damaged proteins) cells exploit homeostasis spatially: If degradation