Brompton cocktail of opioids both to combat the somnolence from the painkillers and to boost their pain-killing ability. However, a 1979 study in the "Canadian Medical Association Journal" found no statistically significant advantage in pain suppression, confusion, nausea, or drowsiness to the Brompton mixture versus a solution of morphine. Brompton cocktail Brompton cocktail — sometimes called a Brompton mixture, Brompton's cocktail — is an elixir meant for use as a pain suppressant, and dosed for prophylaxis. Made from morphine or diacetylmorphine (heroin), cocaine, highly-pure ethyl alcohol (some recipes specify gin), and sometimes with chlorpromazine (Thorazine) to counteract nausea, it was given to
Manhattan (cocktail) to the name of the club where it originated—"the "Manhattan" cocktail". However, Lady Randolph was in France at the time and pregnant, so the story is likely a fiction. However, there are prior references to various similar cocktail recipes called "Manhattan" and served in the Manhattan area. By one account it was invented in the 1860s by a bartender named Black at a bar on Broadway near Houston Street. The original "Manhattan cocktail" was a mix of "American Whiskey, Italian Vermouth and Angostura bitters". During Prohibition (1920–1933) Canadian whisky was primarily used because it was available. An early record of