Brompton cocktail of opioids both to combat the somnolence from the painkillers and to boost their pain-killing ability. However, a 1979 study in the "Canadian Medical Association Journal" found no statistically significant advantage in pain suppression, confusion, nausea, or drowsiness to the Brompton mixture versus a solution of morphine. Brompton cocktail Brompton cocktail — sometimes called a Brompton mixture, Brompton's cocktail — is an elixir meant for use as a pain suppressant, and dosed for prophylaxis. Made from morphine or diacetylmorphine (heroin), cocaine, highly-pure ethyl alcohol (some recipes specify gin), and sometimes with chlorpromazine (Thorazine) to counteract nausea, it was given to
Active ingredient Active ingredient An active ingredient (AI) is the ingredient in a pharmaceutical drug or pesticide that is biologically active. The similar terms active pharmaceutical ingredient (API) and bulk active are also used in medicine, and the term active substance may be used for natural products. Some medication products may contain more than one active ingredient. The traditional word for the API is pharmacon or pharmakon (from , adapted from pharmacos) which originally denoted a magical substance or drug. The terms active constituent or active principle are often chosen when referring to the active substance of interest in a plant (such