IPod Nano had the same price point as the 5th generation device. A firmware update (version 1.1) for the Nano was released on February 28, 2011. The update added the ability to change songs or pause with a double click of the sleep/wake button. It also added the ability to turn the device off by holding the sleep/wake button. The user interface was also enhanced. On October 4, 2011, the iPod Nano 1.2 update was unveiled at the Apple "Let's Talk iPhone" event at the Town Hall, 4 Infinite Loop. This update added the option to increase or decrease the size of
JUNQ and IPOD the late onset of neurodegenerative diseases. In such diseases (e.g. Huntington's disease), a mutated protein misfolds and becomes toxic to the cellular environment by various ways such as denaturating cytosolic proteins. Incompetent of degrading those toxic species, the cell must isolate them to avoid their hazardous interaction with the cellular proteome. The IPOD was shown to be the sub-cellular site to which toxic amyloidogenic proteins are sequestered to, hereby serving as a protective quality control compartment. In addition, it was suggested by the Lindquist group, that the IPOD is the site where yeast prions undergo a maturation process. Thus, the