Saffron (trade) by far the world's most important producer: in 2005 it grossed some of dry threads, or 93.7 percent of the year's global total mass; much of the Iranian crop was bound for export. Northeasterly Khorasan Province, which in 2004 was divided in three, grows 95 percent of Iranian saffron: the hinterlands of Birjand, Ghayen, Ferdows in South Khorasan Province, along with areas abutting Gonabad and Torbat-e Heydarieh in Razavi Khorasan Province, are its key cropping areas. During 2004, Iran was not a member of the World Trade Organization. and still until November 2009, Iran was again not a member of
Saffron is present as 28% of the Daily Value, while other micronutrients have negligible content (table). One limited meta-analysis concluded that saffron supplementation improved symptoms in people with major depressive disorders. Another review of preliminary human research indicated that it may have effects on mild to moderate depression. The documented history of saffron cultivation spans more than three millennia. The wild precursor of domesticated saffron crocus is probably "Crocus cartwrightianus". If "C. sativus" is a mutant form of "C. cartwrightianus", then it may have emerged by human cultivators selectively breeding specimens for unusually long stigmas in late Bronze Age Crete. It