House of Tudor ruled their domains for just over a century. Henry VIII was the only son of Henry VII to live to the age of maturity. Issues around the royal succession (including marriage and the succession rights of women) became major political themes during the Tudor era. The House of Stuart, descended from Henry VII's daughter Margaret, came to power in 1603 when Elizabeth I died and the Tudor line failed. For analysis of politics, diplomacy and social history, see Tudor period. The Tudors descended on Henry VII's mother's side from John Beaufort, 1st Earl of Somerset, one of the illegitimate children
House of Tudor was declared illegitimate after her parents' marriage was annulled, Mary was the strongest legitimate claimant. Despite this, Elizabeth would not name Mary her heir; as she had experienced during the reign of her predecessor Mary I, the opposition could flock around the heir if they were disheartened with Elizabeth's rule. Numerous threats to the Tudor line occurred during Elizabeth's reign. In 1569, a group of Earls led by Charles Neville, the sixth Earl of Westmorland, and Thomas Percy, the seventh Earl of Northumberland attempted to depose Elizabeth and replace her with Mary, Queen of Scots. In 1571, the Protestant-turned-Catholic Thomas