Gujarat South Arabian and Persian Gulf ports, who migrated in and out of Cambay with the rhythm of the monsoons. But others were men with Arab or Persian patronyms whose families had settled in the town generations, even centuries earlier, intermarrying with Gujarati women, and assimilating everyday customs of the Hindu hinterland. The Age of Discovery heralded the dawn of pioneer Portuguese and Spanish long-distance travel in search of alternative trade routes to "the East Indies", moved by the trade of gold, silver and spices. In 1497, Portuguese explorer Vasco da Gama is said to have discovered the Europe-to-India sea route
Portuguese discovery of the sea route to India warn that both the routes would explored by the Portuguese Crown. There is news of an Italian merchant who spread the good news in Florence. The merchant refers to Melinde. With the opening of the sea route to the East Indies, the Venetians, who controlled the trade of the Mediterranean, bought pepper from the Portuguese, at half the price they paid to the Arabs in Egypt. The fall of the Venetian monopoly on the spice trade in Europe and the resulting drop in prices of spices contributed to the commercial development of the continent. Portuguese discovery of the sea route