IPhone 5 Buena Center for the Arts in San Francisco on September 12, 2012. A shadow of the numeral 5 was featured in the invitations sent to the media, suggesting that the next iPhone would be unveiled at the event. At the unveiling, Apple announced the iPhone 5 and also introduced new iPod Nano and iPod Touch models. They also stated that pre-orders would be accepted starting September 14, 2012. Over two million pre-orders were received within 24 hours. Initial demand for the new phone exceeded the record set by its predecessor, the iPhone 4s, by selling over 5 million units in
JUNQ and IPOD the late onset of neurodegenerative diseases. In such diseases (e.g. Huntington's disease), a mutated protein misfolds and becomes toxic to the cellular environment by various ways such as denaturating cytosolic proteins. Incompetent of degrading those toxic species, the cell must isolate them to avoid their hazardous interaction with the cellular proteome. The IPOD was shown to be the sub-cellular site to which toxic amyloidogenic proteins are sequestered to, hereby serving as a protective quality control compartment. In addition, it was suggested by the Lindquist group, that the IPOD is the site where yeast prions undergo a maturation process. Thus, the