IPod that put "1,000 songs in your pocket." Apple did not develop the iPod software entirely in-house, instead using PortalPlayer's reference platform based on two ARM cores. The platform had rudimentary software running on a commercial microkernel embedded operating system. PortalPlayer had previously been working on an IBM-branded MP3 player with Bluetooth headphones. Apple contracted another company, Pixo, to help design and implement the user interface under the direct supervision of Steve Jobs. As development progressed, Apple continued to refine the software's look and feel. Starting with the iPod Mini, the Chicago font was replaced with Espy Sans. Later iPods switched
JUNQ and IPOD the late onset of neurodegenerative diseases. In such diseases (e.g. Huntington's disease), a mutated protein misfolds and becomes toxic to the cellular environment by various ways such as denaturating cytosolic proteins. Incompetent of degrading those toxic species, the cell must isolate them to avoid their hazardous interaction with the cellular proteome. The IPOD was shown to be the sub-cellular site to which toxic amyloidogenic proteins are sequestered to, hereby serving as a protective quality control compartment. In addition, it was suggested by the Lindquist group, that the IPOD is the site where yeast prions undergo a maturation process. Thus, the