IPod Nano game was dropped and replaced with a Maze game which makes use of the iPod's accelerometer similarly to such games on the iPhone and iPod Touch. The fourth generation dropped support for charging via FireWire. "This change means that any dock accessories that use the dock connector's FireWire pins to send power—many older speakers and car chargers, for example—will not charge the fourth-generation iPod Nano." At Apple's September 9, 2009 event, a fifth generation iPod Nano was unveiled with reduced prices on the larger model (at the time of release, the 8GB was priced at $149 and the 16GB at
JUNQ and IPOD and processing of different kinds of misfolded proteins (e.g. ubiquitinated vs. non-ubiquitinated proteins). Segregation of toxic protein aggregates into JUNQ and IPOD inclusion bodies is a means by which mammalian cells can be rejuvenated through asymmetric division. Thus, the discovery of JUNQ and IPOD provided a new striking perspective of how cells manage misfolded aggregated proteins and gave convincing proof that protein aggregation is a non-random, well regulated and controlled cellular process. Furthermore, the discovery of JUNQ and IPOD suggested that in addition to temporal quality control (i.e. time dependent administration of damaged proteins) cells exploit homeostasis spatially: If degradation