Brompton cocktail of opioids both to combat the somnolence from the painkillers and to boost their pain-killing ability. However, a 1979 study in the "Canadian Medical Association Journal" found no statistically significant advantage in pain suppression, confusion, nausea, or drowsiness to the Brompton mixture versus a solution of morphine. Brompton cocktail Brompton cocktail — sometimes called a Brompton mixture, Brompton's cocktail — is an elixir meant for use as a pain suppressant, and dosed for prophylaxis. Made from morphine or diacetylmorphine (heroin), cocaine, highly-pure ethyl alcohol (some recipes specify gin), and sometimes with chlorpromazine (Thorazine) to counteract nausea, it was given to
Cocktail publication of a bartenders' guide which included cocktail recipes was in 1862 – "How to Mix Drinks; or, The Bon Vivant's Companion", by "Professor" Jerry Thomas. In addition to recipes for punches, sours, slings, cobblers, shrubs, toddies, flips, and a variety of other mixed drinks were 10 recipes for "cocktails". A key ingredient differentiating cocktails from other drinks in this compendium was the use of bitters. Mixed drinks popular today that conform to this original meaning of "cocktail" include the Old Fashioned whiskey cocktail, the Sazerac cocktail, and the Manhattan cocktail. The ingredients listed (spirits, sugar, water, and bitters) match