IPhone OS 2 available to the iPhone and iPod Touch. Prior to the public release of iPhone OS 2.0, Apple held a keynote event to announce the iPhone OS Software Development Kit ("SDK") to developers. The most notable feature of iPhone OS 2 was the App Store. Before this feature was introduced, the only way to install custom applications on the device was via jailbreaking, which is strongly discouraged and unsupported by Apple. There were 500 applications available for download at the launch of the App Store, though this amount has grown dramatically since then. Now, the App Store has more than 2
JUNQ and IPOD the late onset of neurodegenerative diseases. In such diseases (e.g. Huntington's disease), a mutated protein misfolds and becomes toxic to the cellular environment by various ways such as denaturating cytosolic proteins. Incompetent of degrading those toxic species, the cell must isolate them to avoid their hazardous interaction with the cellular proteome. The IPOD was shown to be the sub-cellular site to which toxic amyloidogenic proteins are sequestered to, hereby serving as a protective quality control compartment. In addition, it was suggested by the Lindquist group, that the IPOD is the site where yeast prions undergo a maturation process. Thus, the