IPod Touch (5th generation) iOS being iOS 6, iOS 7, iOS 8 and iOS 9. iOS 9 is said by Apple to feature performance improvements that may help the aging device function more smoothly. Other A5-based devices will also support iOS 9 including the iPad 2 (6 major iOS versions), the iPhone 4S (5 major iOS versions) and the iPad Mini (4 major iOS versions). iOS 9.3.5 is the last update that supports the iPod Touch 5th generation as it did not receive iOS 10 along with the iPhone 4S, iPad 2 and 3, and iPad Mini 1st generation due to hardware limitations. The
JUNQ and IPOD the late onset of neurodegenerative diseases. In such diseases (e.g. Huntington's disease), a mutated protein misfolds and becomes toxic to the cellular environment by various ways such as denaturating cytosolic proteins. Incompetent of degrading those toxic species, the cell must isolate them to avoid their hazardous interaction with the cellular proteome. The IPOD was shown to be the sub-cellular site to which toxic amyloidogenic proteins are sequestered to, hereby serving as a protective quality control compartment. In addition, it was suggested by the Lindquist group, that the IPOD is the site where yeast prions undergo a maturation process. Thus, the