IPhone 5C the first three days, which set a record for first weekend smartphone sales, with the 5S selling three times more units than iPhone 5C. After the first day of release, 1% of all iPhone in the US were iPhone 5S, while 0.3% were iPhone 5C.<ref name="cnet iP5S/C sales 1"></ref> Commentators viewed iPhone 5C as a flop because of supply chain cuts signifying a decline in demand in October 2013. Apple CEO Tim Cook admitted that the company overstocked the iPhone 5C while having shortages of the iPhone 5S, as a result of failing to anticipate the sales ratio between both
JUNQ and IPOD the disaggregase chaperone, AAA protein HSP104, localizes to the IPOD. It is yet to be determined if HSP104 functions in the IPOD or is simply sequestered there being hooked to a substrate. The pre-autophagosomal structure (PAS) is localized by the IPOD. However, it wasn't shown that IPOD substrates are delivered to the vacuole, and so the link between the IPOD and autophagy is yet to be determined. JUNQ and IPOD JUNQ and IPOD are types of cytosolic protein inclusion bodies in eukaryotes. Neurodegenerative diseases, such as Parkinson's, Alzheimer's, and Huntington's, are associated and correlated with protein aggregation and accumulation of