IPhone 5 Buena Center for the Arts in San Francisco on September 12, 2012. A shadow of the numeral 5 was featured in the invitations sent to the media, suggesting that the next iPhone would be unveiled at the event. At the unveiling, Apple announced the iPhone 5 and also introduced new iPod Nano and iPod Touch models. They also stated that pre-orders would be accepted starting September 14, 2012. Over two million pre-orders were received within 24 hours. Initial demand for the new phone exceeded the record set by its predecessor, the iPhone 4s, by selling over 5 million units in
JUNQ and IPOD the disaggregase chaperone, AAA protein HSP104, localizes to the IPOD. It is yet to be determined if HSP104 functions in the IPOD or is simply sequestered there being hooked to a substrate. The pre-autophagosomal structure (PAS) is localized by the IPOD. However, it wasn't shown that IPOD substrates are delivered to the vacuole, and so the link between the IPOD and autophagy is yet to be determined. JUNQ and IPOD JUNQ and IPOD are types of cytosolic protein inclusion bodies in eukaryotes. Neurodegenerative diseases, such as Parkinson's, Alzheimer's, and Huntington's, are associated and correlated with protein aggregation and accumulation of