IPhone OS 2 market." iPhone OS 2 cost $9.95 for iPod Touch users; it was free for iPhone users. IPhone OS 2 iPhone OS 2 is the second major release of the iOS mobile operating system developed by Apple Inc., being the successor to iPhone OS 1. It was the first release of iOS to support third-party applications via the App Store. iPhone OS 2.2.1 was the final version of iPhone OS 2. It was succeeded by iPhone OS 3 on June 17, 2009. iPhone OS 2.0 became available on July 11, 2008 with the release of the iPhone 3G. Devices running 1.x
JUNQ and IPOD that protein aggregation may actually be a tightly regulated, organized process, by which the cell protects itself from toxic proteins by sequestration to inclusion bodies. In 2008, Daniel Kaganovich showed that eukaryotic cells sort misfolded proteins into two distinct inclusion bodies in a well-managed cellular process: JUNQ and IPOD are evolutionarily conserved, and are found in specific and defined cellular sites. Delivery of misfolded, aggregated proteins to JUNQ and IPOD require an intact cytoskeleton and specific cellular quality control components, such as Heat Shock Proteins (HSPs). The partition into the two distinct inclusion bodies is due to the different handling