Marx Brothers stage during the middle of a Groucho monologue to see if Groucho would be thrown off. However, to the audience's delight, Groucho merely reacted by commenting, "First time I ever saw a taxi hail a passenger". When Harpo chased the girl back in the other direction, Groucho calmly checked his watch and ad-libbed, "The 9:20's right on time. You can set your watch by the Lehigh Valley." The brothers' vaudeville act had made them stars on Broadway under Chico's management and with Groucho's creative direction—first with the musical revue "I'll Say She Is" (1924–1925) and then with two musical comedies:
Things Which Have Never Yet Been Done (Skyler Wexler) undergoes bone marrow extraction to donate to Cosima in an attempt to cure Cosima's illness. Alison and her husband Donnie (Kristian Bruun) attempt to bury Dr. Aldous Leekie's body, while Helena attempts to escape from the ranch of the Proletheans, a religious extremist group. "Things Which Have Never Yet Been Done" marked the first on-screen appearance of Kathryn Alexandre, who also works on the show as Maslany's "clone double" when filming scenes where multiple clones interact. The episode was filmed at various locations in Toronto and the title was taken from Francis Bacon's work "Novum Organum". It was