Gin which the term "Dutch courage" is believed to have originated. According to some unconfirmed accounts Gin originated in Italy. By the mid-17th century, numerous small Dutch and Flemish distillers had popularized the re-distillation of malt spirit or malt wine with juniper, anise, caraway, coriander, etc., which were sold in pharmacies and used to treat such medical problems as kidney ailments, lumbago, stomach ailments, gallstones, and gout. Gin emerged in England in varying forms by the early 17th century, and at the time of the Restoration, enjoyed a brief resurgence. Gin became vastly more popular as an alternative to brandy, when
Flavour (particle physics) basis to the flavor-eigenstate/mass-eigenstate basis for quarks underlies the Cabibbo–Kobayashi–Maskawa matrix (CKM matrix). This matrix is analogous to the PMNS matrix for neutrinos, and quantifies flavour changes under charged weak interactions of quarks. The CKM matrix allows for CP violation if there are at least three generations. Flavour quantum numbers are additive. Hence antiparticles have flavour equal in magnitude to the particle but opposite in sign. Hadrons inherit their flavour quantum number from their valence quarks: this is the basis of the classification in the quark model. The relations between the hypercharge, electric charge and other flavour quantum numbers hold