IPod Shuffle September 10, 2013, to coincide with the release of the iPhone 5S, the "Slate" color option was replaced with "Space Grey". On July 15, 2015, Apple released 6 new colors (blue, pink, silver, gold, space grey, and Product Red) for the iPod Shuffle. On July 27, 2017, Apple announced that it is discontinuing the iPod shuffle along with the iPod Nano. The iPod Shuffle was announced at the same time as the Mac Mini. Like the iPod Shuffle, the Mac Mini is a scaled-down product which has been introduced at a lower price. These two products together can be seen
JUNQ and IPOD the late onset of neurodegenerative diseases. In such diseases (e.g. Huntington's disease), a mutated protein misfolds and becomes toxic to the cellular environment by various ways such as denaturating cytosolic proteins. Incompetent of degrading those toxic species, the cell must isolate them to avoid their hazardous interaction with the cellular proteome. The IPOD was shown to be the sub-cellular site to which toxic amyloidogenic proteins are sequestered to, hereby serving as a protective quality control compartment. In addition, it was suggested by the Lindquist group, that the IPOD is the site where yeast prions undergo a maturation process. Thus, the