IPod Shuffle September 10, 2013, to coincide with the release of the iPhone 5S, the "Slate" color option was replaced with "Space Grey". On July 15, 2015, Apple released 6 new colors (blue, pink, silver, gold, space grey, and Product Red) for the iPod Shuffle. On July 27, 2017, Apple announced that it is discontinuing the iPod shuffle along with the iPod Nano. The iPod Shuffle was announced at the same time as the Mac Mini. Like the iPod Shuffle, the Mac Mini is a scaled-down product which has been introduced at a lower price. These two products together can be seen
JUNQ and IPOD IPOD may serve not only as a sequestration site, but also as a functional compartment. The IPOD is a non- membrane bound cellular site, which in yeast is located by the vacuole. FRAP and FLIP assays revealed that proteins in the IPOD are tightly packed, in-soluble and don't exchange with the cytosol. Amyloidogenic proteins, such as the Huntingtin protein, are the IPOD's substrates. Misfolded proteins must be non-ubiquitinated to be sorted to the IPOD. Ubiquitination of an otherwise IPOD substrate, such as the RNQ1 fungal prion, will result in its sequestration in the JUNQ inclusion. Upon accumulation of misfolded proteins,