Lorraine Heggessey involved in the dismissal of "Blue Peter" presenter Richard Bacon. In October 1998, the "News of the World" newspaper revealed that Bacon had taken cocaine, and he was subsequently sacked from his job as a presenter on the high-profile children's programme. Heggessey appeared on-screen in a specially-recorded one-minute address to viewers shown directly before the first episode of "Blue Peter" to be screened following Bacon's sacking, on 19 October 1998, to explain to young viewers why Bacon had been dismissed, claiming that he had "not only let himself and the team on "Blue Peter" down, but he has also let
Epigenetics of cocaine addiction concluded that ΔFosB, CREB, Sirt1 and Sirt2 all play an integral role in cocaine-seeking behaviors. Kumar et al. focused on how acute and chronic cocaine exposure affected the striatum, which is another area of the brain involved in the reward and locomotor pathways. To study the molecular actions of cocaine in this region, researchers studied the histone modifications of three different promoters: "cFos", "BDNF", and "Cdk5". They saw that "cFos", which is normally expressed immediately after neurons fire action potentials, had high levels of H4 acetylation within 30 minutes of a cocaine injection – but no histone modifications were seen