Classes of metals products with soft bases, which are bases with covalent bonds. The IUPAC Gold Book provides a more general definition of a class (a) metal ion, as "A metal ion that combines preferentially with ligands containing ligating atoms that are the lightest of their Periodic Group", and a class (b) metal as one that combines preferentially with ligands containing ligating atoms other than the lightest of their Periodic Group. Classes of metals Class A metals are metals that form hard acids. Hard acids are acids with relatively ionic bonds. These metals, such as iron, aluminium, titanium, sodium, calcium and the lanthanides,
Poxvirus AX element late mRNA cis-regulatory element Poxvirus AX element late mRNA cis-regulatory element The Poxvirus AX element late mRNA family represents a "cis"-regulatory element present at the 3' end of poxvirus late ATI mRNA and is known as the AX element. The AX element is involved in directing the efficient production and orientation-dependent formation of late RNAs. It is likely that this element directs the endonucleolytic cleavage of the transcript. It has been shown that the F17R late mRNA transcript which is also cleaved is also likely to share a common factor in their mechanism despite a lack of any obvious similarity in its cis-regulatory RNA