Trimethylamine N-oxide Trimethylamine N-oxide Trimethylamine "N"-oxide (TMAO) is an organic compound with the formula (CH)NO. It is in the class of amine oxides. Although the anhydrous compound is known, trimethylamine "N"-oxide is usually encountered as the dihydrate. It is a product of the oxidation of trimethylamine, a common metabolite in animals. Both the anhydrous and hydrated materials are white, water-soluble solids. Trimethylamine "N"-oxide is an osmolyte found in saltwater fishes, sharks, rays, molluscs, and crustaceans. It is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. It is also higher in deep-sea
Should've Known Better (Richard Marx song) for two weeks and remained on the chart for 13 weeks. Elsewhere, the single reached number 50 in the United Kingdom. Should've Known Better (Richard Marx song) "Should've Known Better" is a hit song written, composed, and performed by American rock singer Richard Marx, who released in September 1987 as the second single from his self-titled debut album. The song peaked at number three on the US "Billboard" Hot 100 as well as #7 on the "Billboard" Mainstream Rock Tracks chart in 1987 and #4 on the Radio & Records CHR/Pop Airplay chart. Marx became the first solo artist in