Andy Murray reached the semi-finals of the Rakuten Japan Open after entering as defending champion. He was beaten by Milos Raonic in a close three-set match. He was defending champion in the doubles with his brother Jamie. However, they were knocked out in the quarter-finals by top seeds Leander Paes and Radek Štěpánek. At the penultimate Masters 1000 tournament of the year in Shanghai, after receiving a bye into round two, Murray's first match was due to be played against Florian Mayer. However, Mayer had to pull out due to injury, giving Murray a walkover into round three. After beating Alexandr Dolgopolov
Andy Murray Ranked No. 312, Murray became the first Scot in the Open Era to reach the third round of the men's singles tournament at Wimbledon. In the third round, Murray lost to 2002 Wimbledon finalist David Nalbandian due to cramping and fatigue, having led two sets to love. Following Wimbledon, Murray won Challenger events on the hard courts of Aptos and Binghamton, New York. He then experienced his first Masters event at Cincinnati, where he beat Taylor Dent, before losing in three sets to then-No. 4, Marat Safin. With a wild card entry, Murray played Andrei Pavel in the opening round