Prehistoric technology Ground and polished stone tools continued to be created and used during the Neolithic period. Numeric record keeping evolved from a system of counting using small clay tokens that began in Sumer about 8000 BC. The Stone Age developed into the Bronze Age after the Neolithic Revolution. The Neolithic Revolution involved radical changes in agricultural technology which included development of agriculture, animal domestication, and the adoption of permanent settlements. The Bronze Age is characterised by metal smelting of copper and its alloy bronze, an alloy of tin and copper, to create implements and weapons. Polished stone tools continued to be
Antimicrobial copper-alloy touch surfaces in rooms with copper touch surfaces were significantly lower than in rooms without copper surfaces. "Staphylococci" were the most predominant microorganism isolated and copper was effective in reducing the "Staphylococci" microbial burden. Further studies regarding the clinical implications of copper's intrinsic ability to reduce microbial burdens in hospitals are being planned. Researchers from the Kitasato University School of Medicine conducted antimicrobial studies of "S. aureus", "E. coli", and "P. aeruginosa" on various Japanese copper alloy coins and on copper alloy plates. The microbes were strains from hospital environments. Copper and its nickel-silver, cupronickel, and brass alloys were found to kill