Cocktail umbrella to the fact that the Hawaiian margarita contains tequila instead of rum. Nobody is quite certain exactly when the cocktail umbrella came into use. One possible source is Donn Beach, owner of the Hollywood, California-based restaurant and bar chain Don the Beachcomber. According to cocktail historian Dale DeGroff, Beach started the trend in 1932 after spending much of his time collecting things from around the world, most notably from the South Pacific. Beach sold his merchandise, including the cocktail umbrellas, to Victor Bergeron, owner of the Emeryville, California-based bar chain Trader Vic’s. According to Bergeron’s son Joe, Trader Vic’s used
Cooperstown cocktail probe for CYP2C9. The '+ 1' refers to the vitamin K that is given together with the warfarin to prevent any anticoagulant effect. The Cooperstown cocktail and the Cooperstown 5 + 1 cocktail are powerful tools for investigating the activity of important drug metabolising enzymes. They are used in human drug interaction studies in which the ability of a study drug to inhibit or induce cytochrome p450 enzymes is studied. Cooperstown cocktail The Cooperstown cocktail refers to a panel of four drug probes used in human pharmacokinetic studies to determine the activity of drug metabolising enzymes. The terminology 'cocktail' refers