Andy Murray the victory to former player Elena Baltacha. He then lost to qualifier Santiago Giraldo in the following round. Murray then reached the quarter-finals of the Rome Masters where he lost to No. 1 Rafael Nadal in a tight match in which he had been up a break in the final set. At the French Open, Murray defeated Andrey Golubev and Marinko Matosevic before edging out 28th seed Philipp Kohlschreiber 12–10 in the final set. This was the first time Murray had ever gone beyond 7–5 in a deciding set. He followed this up with a straight sets win over Fernando
Jamie Murray Championships respectively, but failed to progress beyond the third round of Wimbledon. Murray had a public fall out with brother Andy Murray, criticising him for dropping out of the World Group first round tie against Argentina over fears he could aggravate a knee injury. Jamie played in and lost the doubles match with Ross Hutchins. Great Britain eventually lost 4–1. This was Great Britain's first World Group match since 2003, now facing a relegation play-off with Austria. The Murrays would not speak to each other for two weeks. At the Olympic Games, the two Murrays competed together in the doubles