International Society of Nephrology research, diagnosis, treatment, and prevention of kidney disease. The ISN has over 9,000 professional members from more than 126 countries. In addition, the ISN closely collaborates with over 75 national and regional nephrology societies around the world, representing about 20,000 professionals. The ISN continues to develop and consolidate several programs, initiatives and partnerships that will help to further deliver on its two overarching goals: reducing the incidence and impact of kidney disease worldwide, and making the ISN the leading international organization for all issues related to the science and practice of global nephrology. In 1992 the society formed a task
The six organs in the Palace of Mafra organs were produced that year. Shortly after their completion, the French invasion and the following exile of the Portuguese Court to Brazil led to the organs decaying for lack of maintenance. A decade later – possibly in connection with the prospect of the return of the Portuguese royal family – the six organs were subject to a major intervention. The intent of these works, undertaken by Machado e Cerveira, was not only to repair the instruments but also to enlarge them. Unfortunately, the works were interrupted a few years later (Machado e Cerveira died in 1828), and several items, such