International Society of Nephrology research, diagnosis, treatment, and prevention of kidney disease. The ISN has over 9,000 professional members from more than 126 countries. In addition, the ISN closely collaborates with over 75 national and regional nephrology societies around the world, representing about 20,000 professionals. The ISN continues to develop and consolidate several programs, initiatives and partnerships that will help to further deliver on its two overarching goals: reducing the incidence and impact of kidney disease worldwide, and making the ISN the leading international organization for all issues related to the science and practice of global nephrology. In 1992 the society formed a task
Circumventricular organs is also hypothesized that the VOLT may be the mechanism through which pyrogens function to initiate a febrile response in the CNS. Finally, VOLT neurons have been observed to respond to temperature changes indicating that the organum vasculosum of the lamina terminalis is subject to different climates. The subfornical organ is a sensory CVO situated in the lamina terminalis and lacking the BBB, the absence of which characterizes the circumventricular organs. Protruding into the third ventricle of the brain, the highly vascularized SFO can be divided into 3–4 anatomical zones, especially by its capillary density and structure. The central zone