Proton pack of the gun to represent the beam. Proton pack The proton pack is an energy weapon used for weakening ghosts and aiding in capturing them within the "Ghostbusters" universe. First depicted in the film "Ghostbusters", it has a hand-held wand ("Neutrona Wand" or particle thrower) connected to a backpack-sized particle accelerator. It fires a stream of highly focused and radially polarized protons that electrostatically traps the negatively charged energy of a ghost, allowing it to be held in the stream. The proton pack, designed by Dr. Egon Spengler, is a man-portable particle accelerator system that is used to create a
Pictet–Spengler reaction hydrochloric acid forming a tetrahydroisoquinoline. Like the Mannich reaction, aldehydes give good yields while ketones tend to give lower conversion. The Pictet–Spengler reaction has been applied to solid-phase combinatorial chemistry with great success. An analogous reaction with an aryl-β-ethanol is called Oxa-Pictet–Spengler reaction The reaction mechanism occurs by initial formation of an iminium ion (2) followed by electrophilic addition at the 3-position, in accordance with the expected nucleophilicity of indoles, to give the spirocycle 3. After migration of the best migrating group, deprotonation gives the product (5). Replacing an indole with a 3,4-dimethoxyphenyl group give the reaction named the Pictet–Spengler