Ghostbusters franchise, which includes a 1989 sequel, "Ghostbusters II", two animated television series, "The Real Ghostbusters" and "Extreme Ghostbusters", several video games, and a 2016 reboot film. Peter Venkman, Raymond Stantz, and Egon Spengler are scientists investigating the paranormal at Columbia University. After they lose their jobs following a botched ghost investigation in the University library, they establish Ghostbusters, a paranormal investigation and elimination service. They open their business in a disused firehouse and develop high-tech equipment to capture ghosts. On their first call, at a hotel, Egon warns the group never to cross the energy streams of their proton pack
Pictet–Spengler reaction imine generated from the condensation of the aldehyde and amine. This helps to explain the need for an acidic medium in some substrates, as the imine may not be electrophilic enough for ring closure to occur but the Iminium ion is capable of undergoing the reaction. The Pictet-Spengler reaction is widespread in both human industry and biosynthesis. It has remained an important reaction in the fields of alkaloid and pharmaceutical synthesis since its inception, where it has been employed in the development of many beta-carbolines. The enzyme strictosidine synthase is an example of nature utilizing the Pictet-Spengler reaction, which generates