Hemingway Special Hemingway Special A Hemingway Special is an all day cocktail based on the Floridita Daiquiri and is recognised by the IBA. It is made with rum, lime juice, maraschino liqueur, and grapefruit juice and served in a double cocktail glass. While he was staying in Cuba, Ernest Hemingway tried the Floridita's signature drink, the Floridita Daiquiri, and said "That's good but I prefer it without sugar and double rum," creating a cocktail now known as the Hemingway Daiquiri or the Papa Doble. This recipe was later modified further, adding grapefruit juice to the mix, at which point the drink was
Cooperstown cocktail probe for CYP2C9. The '+ 1' refers to the vitamin K that is given together with the warfarin to prevent any anticoagulant effect. The Cooperstown cocktail and the Cooperstown 5 + 1 cocktail are powerful tools for investigating the activity of important drug metabolising enzymes. They are used in human drug interaction studies in which the ability of a study drug to inhibit or induce cytochrome p450 enzymes is studied. Cooperstown cocktail The Cooperstown cocktail refers to a panel of four drug probes used in human pharmacokinetic studies to determine the activity of drug metabolising enzymes. The terminology 'cocktail' refers