Alloy was used by the Inuit people. Native copper, however, was found worldwide, along with silver, gold, and platinum, which were also used to make tools, jewelry, and other objects since Neolithic times. Copper was the hardest of these metals, and the most widely distributed. It became one of the most important metals to the ancients. Eventually, humans learned to smelt metals such as copper and tin from ore, and, around 2500 BC, began alloying the two metals to form bronze, which was much harder than its ingredients. Tin was rare, however, being found mostly in Great Britain. In the Middle
Antimicrobial copper-alloy touch surfaces surfaces typically manufactured with standard materials (i.e., plastic, chrome, aluminum) were replaced with copper alloys. These included a copper alloy set of sink tap handles (60% Cu, 40% Zn) and a ward entrance door push plate (70% Cu, 30% Zn). Contamination reductions of 90–100% were observed for "Staphylococcus aureus", "Escherichia coli", "Klebsiella pneumoniae", "Acinetobacter baumanii", "Enterococcus" spp., and "Candida albicans" on the copper alloy surfaces versus the non-copper standard surfaces. A microorganism reduction of 100% was observed on the hot tap copper alloy handle. The high degree of clinical performance suggested that copper alloy surfaces may increase the effectiveness of