Units of paper quantity of 480 sheets, now known as a 'short' ream. Reams of 472 and 516 sheets are still current, but in retail outlets paper is typically sold in reams of 500. As an old UK and US unit, a perfect ream was equal to 516 sheets. Certain types of specialist papers such as tissue paper, greaseproof paper, handmade paper, and blotting paper are still sold (especially in the UK) in 'short' reams of 480 sheets (20 quires of 24 sheets). However, the commercial use of the word 'ream' for quantities of paper other than 500 is now deprecated by such standards
First Folio texts were beyond the typesetters' capacity to correct. The Folio was typeset and bound in "sixes" – 3 sheets of paper, taken together, were folded into a booklet-like quire or gathering of 6 leaves, 12 pages. Once printed, the "sixes" were assembled and bound together to make the book. The sheets were printed in 2-page formes, meaning that pages 1 and 12 of the first quire were printed simultaneously on one side of one sheet of paper (which became the "outer" side); then pages 2 and 11 were printed on the other side of the same sheet (the "inner" side).