Egon Spengler a P.K.E. surge of dangerous proportions. Egon was particularly critical of Walter Peck's actions, and his attitude that the Ghostbusters were responsible for the explosion of the containment unit that occurred when Peck ordered a municipal worker to shut the unit down. After their encounter with Stay Puft, Egon suggested an atypical solution when he recommended blasting Gozer's dimensional portal while crossing the proton streams to reverse the particle flow and send Gozer back to his/its dimension. Egon once tried to drill a hole in his own head (a process known as trepanning), which he says "would have worked" if
Pictet–Spengler reaction amination. The benzyl group can be removed hydrogenolytically afterwards. As a rough rule, C NMR signals for C1 and C3 are downfield shifted in "cis" products relative to "trans" products (see steric compression effect). Pictet–Spengler reaction The Pictet–Spengler reaction is a chemical reaction in which a β-arylethylamine undergoes condensation with an aldehyde or ketone followed by ring closure. The reaction was first discovered in 1911 by Amé Pictet and Theodor Spengler. Traditionally an acidic catalyst in protic solvent was employed with heating, however the reaction has been shown to work in aprotic media without acid catalysis in superior yields for