Dihydrogen monoxide parody story has since been used in science education to encourage critical thinking and discussion of the scientific method. A 1983 April Fools' Day edition of the "Durand Express", a weekly newspaper in Durand, Michigan, reported that "dihydrogen oxide" had been found in the city's water pipes, and warned that it was fatal if inhaled, and could produce blistering vapors. The first appearance of the parody on the Internet was attributed by the "Pittsburgh Post-Gazette" to the so-called "Coalition to Ban Dihydrogen Monoxide", a parody organization at UC Santa Cruz following on-campus postings and newsgroup discussions in 1990. This new version
Biological functions of nitric oxide dilates the pulmonary vasculature and, because of efficient scavenging by hemoglobin, has minimal effect on the vasculature of the entire body. Inhaled nitric oxide appears to increase the partial pressure of arterial oxygen (PO) by dilating pulmonary vessels in better-ventilated areas of the lung, moving pulmonary blood flow away from lung segments with low ventilation/perfusion (V/Q) ratios toward segments with normal or better ratios. Nitric oxide is absorbed systemically after inhalation. Most of it moves across the pulmonary capillary bed where it combines with hemoglobin that is 60% to 100% oxygen-saturated. Nitrate has been identified as the predominant nitric oxide