Trimethylamine N-oxide Trimethylamine N-oxide Trimethylamine "N"-oxide (TMAO) is an organic compound with the formula (CH)NO. It is in the class of amine oxides. Although the anhydrous compound is known, trimethylamine "N"-oxide is usually encountered as the dihydrate. It is a product of the oxidation of trimethylamine, a common metabolite in animals. Both the anhydrous and hydrated materials are white, water-soluble solids. Trimethylamine "N"-oxide is an osmolyte found in saltwater fishes, sharks, rays, molluscs, and crustaceans. It is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. It is also higher in deep-sea
Dihydrogen bond via dihydrogen bonding. This kind of H−H interaction is distinct from the H−H bonding interaction in transition metal complexes having dihydrogen bound to a metal. So-called hydrogen hydrogen bond interactions have been proposed to occur between two neutral non-bonding hydrogen atoms from Atoms in molecules theory, while similar interactions have been shown to exist experimentally. Many of these types of dihydrogen bonds have been identified in molecular aggregates. Dihydrogen bond In chemistry, a dihydrogen bond is a kind of hydrogen bond, an interaction between a metal hydride bond and an OH or NH group or other proton donor. With a