Egon Spengler exhausting trek up the stairs of 55 Central Park West. While in the alternate dimension of the library, Egon is heard to groan, "Oh no," and when Ray asks if he saw something scary, Egon replies, "Stairs, lots of stairs". Before the "Return to Sedgewick Hotel" mission, Stantz comments that Spengler was once a coroner, to which he replied that he maintains interest in the subject as a hobby. Spengler appears in Beeline's "Ghostbusters" game for iOS alongside his niece, Michelle Ying. The game was released on January 24, 2013. Spengler appears in "Lego Dimensions", with archival audio of Harold
Pictet–Spengler reaction amination. The benzyl group can be removed hydrogenolytically afterwards. As a rough rule, C NMR signals for C1 and C3 are downfield shifted in "cis" products relative to "trans" products (see steric compression effect). Pictet–Spengler reaction The Pictet–Spengler reaction is a chemical reaction in which a β-arylethylamine undergoes condensation with an aldehyde or ketone followed by ring closure. The reaction was first discovered in 1911 by Amé Pictet and Theodor Spengler. Traditionally an acidic catalyst in protic solvent was employed with heating, however the reaction has been shown to work in aprotic media without acid catalysis in superior yields for