Oscar de la Renta married Annette Engelhard (born 1939), daughter of Fritz Mannheimer and his wife Jane née Reiss, and adoptive daughter of her mother's second husband, Charles W. Engelhard, Jr. De la Renta had stepchildren from both marriages. His son-in-law Alex Bolen currently operates as Chief Executive Officer, and stepdaughter Eliza Bolen serves as Vice President of Licensing at Oscar de la Renta, LLC. De la Renta was regarded as an unofficial ambassador of the Dominican Republic, his home country, and held a diplomatic passport. He had homes there in Casa de Campo and Punta Cana, in addition to his residence in Kent,
Oscar de la Renta served as a board member of the Metropolitan Opera, Carnegie Hall and WNET. He served on the boards of several charitable institutions such as New Yorkers for Children, the America's Society. He was chairman of the Queen Sofía Spanish Institute. He received an honorary degree from Hamilton College (New York) on 26 May 2013. In February 2014, Oscar de la Renta recreated his entire Spring presentation, "Designed for A Cure 2014 collection", to raise money for the Sylvester Comprehensive Cancer Center at the University of Miami Leonard M. Miller School of Medicine. In 2014, de la Renta was the recipient