History of football in England in 1978 and the UEFA Cup in 1981. They also came second in the league in 1981 and 1982. During this period transfer fees began to rise rapidly as more money entered the game; Trevor Francis became Britain's first million-pound footballer in February 1979 when he signed for Nottingham Forest, whose full-back Viv Anderson had just become England's first black international player, a landmark which reflected the growing number of non-white players in the English game. In October 1981, Bryan Robson became England's first £1.5million footballer with his transfer from West Bromwich Albion to Manchester United. However, hooliganism continued to
Antigen transfer in the thymus manifestations of autoimmunity which points to their importance in central tolerance. Indeed, as mTECs represent exclusive "donors of TRAs", experiments with first antigen transfer mouse models discovered thymic dendritic cells (DCs) to be so far the only known "TRAs acceptors" involved in antigen transfer. Indispensability of DCs for the establishment of central tolerance was further verified by recent analysis, which revealed that DCs mediate both recessive and dominant tolerance, with preference for the latter, via presentation of more common TRAs. The most efficient subset in TRA presentation and both modes of central tolerance was found to be CD8α thymic-derived DCs