Lorraine Heggessey involved in the dismissal of "Blue Peter" presenter Richard Bacon. In October 1998, the "News of the World" newspaper revealed that Bacon had taken cocaine, and he was subsequently sacked from his job as a presenter on the high-profile children's programme. Heggessey appeared on-screen in a specially-recorded one-minute address to viewers shown directly before the first episode of "Blue Peter" to be screened following Bacon's sacking, on 19 October 1998, to explain to young viewers why Bacon had been dismissed, claiming that he had "not only let himself and the team on "Blue Peter" down, but he has also let
Epigenetics of cocaine addiction placebo, it was found that HDAC inhibitors had a significant effect on lowering cocaine-seeking behavior. This also suggests an epigenetic mechanism involved in HDAC chromatin regulation. The data is crucial to proving the hypothesis that trichostatin A can remodel chromatin structure and prevent behavioral changes following cocaine exposure. Tests also revealed that HDAC inhibitor administration can not only prevent addiction, but also helps reduce the risk of a relapse in cocaine addicts in the rat model system. As the previous findings suggest, chronic cocaine use caused both alterations in the chromatin remodeling activity of HDACs and drug seeking behavior. Renthal