Arsenic & Old Lace Arsenic & Old Lace Arsenic & Old Lace is a 1962 television film directed by George Schaefer and starring Tony Randall. It first aired during season 11 of the NBC anthology series "Hallmark Hall of Fame". It is an adaptation of Joseph Kesselring's 1939 play "Arsenic and Old Lace". Boris Karloff reprised his role as Jonathan Brewster (who is described by the other characters as resembling the "Frankenstein" star), which he had originated on Broadway. He had been unable to appear in Frank Capra's 1944 film due to a scheduling conflict, but had played Jonathan on television once before, in
Eps-Associated RNA element Eps-Associated RNA element The "eps"-Associated RNA element (EAR; also called "epsC" motif) is a conserved RNA motif associated with exopolysaccharide ("eps") or capsule biosynthesis genes in a subset of bacteria classified within the order Bacillales. It was initially discovered in "Bacillus subtilis", located between the second and third gene in the "eps" operon (i.e., between "epsB" and "epsC"). Deletion of the EAR element impairs biofilm formation. The combination of comparative sequence alignments and structural probing data revealed that the secondary structure of the EAR RNA consists of five helical segments (P1-P5) and a pseudoknot (see diagram). In general, mutations that