Egon Spengler portraying the character other than to follow Ramis's example. He got the part anyway and said in an interview that he did two different takes: in which he impersonated Ramis, the other in which he tried a more "Woody Allen"-like approach that did not suit the character's physicality, he admitted. Egon Spengler is a tall, laconic, bespectacled, awkward member of the team responsible for the main theoretical framework for their paranormal/quantum studies. Being addicted to science, he is the creator of the Ghostbusters' equipment along with Raymond Stantz, thus making him the brains of the Ghostbusters. Although book smart, Spengler
Pictet–Spengler reaction imine generated from the condensation of the aldehyde and amine. This helps to explain the need for an acidic medium in some substrates, as the imine may not be electrophilic enough for ring closure to occur but the Iminium ion is capable of undergoing the reaction. The Pictet-Spengler reaction is widespread in both human industry and biosynthesis. It has remained an important reaction in the fields of alkaloid and pharmaceutical synthesis since its inception, where it has been employed in the development of many beta-carbolines. The enzyme strictosidine synthase is an example of nature utilizing the Pictet-Spengler reaction, which generates