Egon Spengler portraying the character other than to follow Ramis's example. He got the part anyway and said in an interview that he did two different takes: in which he impersonated Ramis, the other in which he tried a more "Woody Allen"-like approach that did not suit the character's physicality, he admitted. Egon Spengler is a tall, laconic, bespectacled, awkward member of the team responsible for the main theoretical framework for their paranormal/quantum studies. Being addicted to science, he is the creator of the Ghostbusters' equipment along with Raymond Stantz, thus making him the brains of the Ghostbusters. Although book smart, Spengler
Pictet–Spengler reaction is created. Several substrate- or auxiliary-controlled diastereoselective Pictet–Spengler reactions have been developed. Additionally, List "et al." have published a chiral Brønsted acid that catalyzes asymmetric Pictet–Spengler reactions. Tryptophans: diastereocontrolled reaction The reaction of enantiopure tryptophan or its short-chain alkylesters leads to 1,2,3,4-tetrahydro-"β"-carbolines in which a new chiral center at C-1 adopts either a "cis" or "trans" configuration towards the C-3 carboxyl group. The "cis" conduction is kinetically controlled, i.e. it is performed at lower temperatures. At higher temperatures the reaction becomes reversible and usually favours racemisation. 1,3-"trans" dominated products can be obtained with "N"-benzylated tryptophans, which are accessible by reductive