Trimethylamine N-oxide Trimethylamine N-oxide Trimethylamine "N"-oxide (TMAO) is an organic compound with the formula (CH)NO. It is in the class of amine oxides. Although the anhydrous compound is known, trimethylamine "N"-oxide is usually encountered as the dihydrate. It is a product of the oxidation of trimethylamine, a common metabolite in animals. Both the anhydrous and hydrated materials are white, water-soluble solids. Trimethylamine "N"-oxide is an osmolyte found in saltwater fishes, sharks, rays, molluscs, and crustaceans. It is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. It is also higher in deep-sea
U Should've Known Better producers, which included Dallas Austin, production team Soulshock & Karlin, Bryan Michael Cox, and Rodney Jerkins and his Darkchild crew. Though she "had never thought about writing much" by then, her producers encouraged the singer to intensify her work on the "All Eyez on Me" album and to write and contribute own lyrics and ideas to the songs, one of which was the ballad "U Should've Known Better." Monica penned the song along with Harold Lilly and longtime contributor Jermaine Dupri, while production on the track was helmed by Dupri and Bryan Michael Cox. "U Should've Known Better" was mixed