Trimethylamine N-oxide Trimethylamine N-oxide Trimethylamine "N"-oxide (TMAO) is an organic compound with the formula (CH)NO. It is in the class of amine oxides. Although the anhydrous compound is known, trimethylamine "N"-oxide is usually encountered as the dihydrate. It is a product of the oxidation of trimethylamine, a common metabolite in animals. Both the anhydrous and hydrated materials are white, water-soluble solids. Trimethylamine "N"-oxide is an osmolyte found in saltwater fishes, sharks, rays, molluscs, and crustaceans. It is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. It is also higher in deep-sea
Should've Known Better (Richard Marx song) Should've Known Better (Richard Marx song) "Should've Known Better" is a hit song written, composed, and performed by American rock singer Richard Marx, who released in September 1987 as the second single from his self-titled debut album. The song peaked at number three on the US "Billboard" Hot 100 as well as #7 on the "Billboard" Mainstream Rock Tracks chart in 1987 and #4 on the Radio & Records CHR/Pop Airplay chart. Marx became the first solo artist in recording history to reach the top three of the Billboard Hot 100 with four singles from a debut album. In the