Ghostbusters franchise, which includes a 1989 sequel, "Ghostbusters II", two animated television series, "The Real Ghostbusters" and "Extreme Ghostbusters", several video games, and a 2016 reboot film. Peter Venkman, Raymond Stantz, and Egon Spengler are scientists investigating the paranormal at Columbia University. After they lose their jobs following a botched ghost investigation in the University library, they establish Ghostbusters, a paranormal investigation and elimination service. They open their business in a disused firehouse and develop high-tech equipment to capture ghosts. On their first call, at a hotel, Egon warns the group never to cross the energy streams of their proton pack
Pictet–Spengler reaction is created. Several substrate- or auxiliary-controlled diastereoselective Pictet–Spengler reactions have been developed. Additionally, List "et al." have published a chiral Brønsted acid that catalyzes asymmetric Pictet–Spengler reactions. Tryptophans: diastereocontrolled reaction The reaction of enantiopure tryptophan or its short-chain alkylesters leads to 1,2,3,4-tetrahydro-"β"-carbolines in which a new chiral center at C-1 adopts either a "cis" or "trans" configuration towards the C-3 carboxyl group. The "cis" conduction is kinetically controlled, i.e. it is performed at lower temperatures. At higher temperatures the reaction becomes reversible and usually favours racemisation. 1,3-"trans" dominated products can be obtained with "N"-benzylated tryptophans, which are accessible by reductive