Simon Thomas (presenter) 2:1 BA Hons degree in history. Having applied for the job three times, Thomas began presenting the children's programme "Blue Peter" on 8 January 1999 replacing the sacked presenter Richard Bacon. Previously he had worked as a runner at Children's BBC and the radio station LBC. During his tenure at "Blue Peter", he ran in the London Marathon twice and two Great North Runs, climbed Mount Kilimanjaro and Mont Blanc, completed over 40 solo sky dives with the Royal Air Force, presented a medal at the Commonwealth Games, ran in the 60 metres sprint at the Norwich Union Indoor Athletics
Epigenetics of cocaine addiction but these other locations had no effect on the cocaine-seeking behavior of rats. The role of sirtuin deacetylases have also been shown to play a role in mediating cocaine addiction. To determine their role, the two transcription factors previously mentioned, ΔFosB and CREB, first had to be analyzed. It has been previously stated that ΔFosB increases the cocaine-seeking behavior of users. This is because ΔFosB has a uniquely stable structure that allows it to persist and accumulate in the body. Unlike ΔFosB, CREB is responsible for reducing sensitivity to cocaine which causes negative symptoms during the withdrawal period. Each of