Study of Health in Pomerania Pomeranian adult population. In the Northeast of Germany nearly 50% - 60% indicate these diseases. SHIP is the first population based cohort study worldwide which includes whole-body MRI. The aims of the following main whole body-MRI study are: (1)To provide prevalence estimates for different MR findings in a general adult population. (2)To establish population-based MRI reference parameters for various organs and organ parts such as left and right ventricular size or volume of liver, spleen, kidney, prostate, and brain structures . Clinical MR reference parameters currently in use were derived from small, nonrepresentative samples and are thus prone to selection
Circumventricular organs Circumventricular organs Circumventricular organs (CVOs) are structures in the brain characterized by their extensive and highly permeable microvasculature, unlike those in the rest of the brain where there exists a blood brain barrier (BBB). The term "circumventricular organs" was originally proposed in 1958 by Austrian anatomist Helmut Hofer, in recognition of the distribution of the structures around the ventricular system of the brain. The circumventricular organs are midline structures around the third and fourth ventricles that are in contact with blood and cerebrospinal fluid, and allow for the linkage between the central nervous system and peripheral blood. Additionally, they are