Egon Spengler the love interest of Janine Melnitz, the Ghostbusters' secretary, in the first film and both animated series ("Ghostbusters II" excluded their romance due to Ramis' dislike of the subplot, thus having Melnitz date Louis Tully instead). Spengler sometimes appears to be unaware of Melnitz's romantic interest in him, but at times he displays having similar feelings for her, such as when he gave her a geranium as a gift when she expressed an interest in plants (which backfired horribly when it was revealed that the geranium was possessed by a ghost and nearly destroyed her apartment, along with much of
Pictet–Spengler reaction amination. The benzyl group can be removed hydrogenolytically afterwards. As a rough rule, C NMR signals for C1 and C3 are downfield shifted in "cis" products relative to "trans" products (see steric compression effect). Pictet–Spengler reaction The Pictet–Spengler reaction is a chemical reaction in which a β-arylethylamine undergoes condensation with an aldehyde or ketone followed by ring closure. The reaction was first discovered in 1911 by Amé Pictet and Theodor Spengler. Traditionally an acidic catalyst in protic solvent was employed with heating, however the reaction has been shown to work in aprotic media without acid catalysis in superior yields for