Andy Murray reached the semi-finals of the Rakuten Japan Open after entering as defending champion. He was beaten by Milos Raonic in a close three-set match. He was defending champion in the doubles with his brother Jamie. However, they were knocked out in the quarter-finals by top seeds Leander Paes and Radek Štěpánek. At the penultimate Masters 1000 tournament of the year in Shanghai, after receiving a bye into round two, Murray's first match was due to be played against Florian Mayer. However, Mayer had to pull out due to injury, giving Murray a walkover into round three. After beating Alexandr Dolgopolov
Andy Roddick fourth round, before being upset by unseeded and eventual finalist, Marcos Baghdatis. At the French Open, Roddick retired in the first round, after sustaining a foot injury during the match. Two weeks later at Wimbledon, Roddick was upset in the third round by British hopeful Andy Murray. This loss caused Roddick to fall below the top 10 for the first time since 2002. After Wimbledon, Roddick began working with a new coach, tennis legend Jimmy Connors. In his first event with his new coach, Roddick reached the final of Indianapolis, before losing to good friend and fellow American, James Blake.