Study of Health in Pomerania Pomeranian adult population. In the Northeast of Germany nearly 50% - 60% indicate these diseases. SHIP is the first population based cohort study worldwide which includes whole-body MRI. The aims of the following main whole body-MRI study are: (1)To provide prevalence estimates for different MR findings in a general adult population. (2)To establish population-based MRI reference parameters for various organs and organ parts such as left and right ventricular size or volume of liver, spleen, kidney, prostate, and brain structures . Clinical MR reference parameters currently in use were derived from small, nonrepresentative samples and are thus prone to selection
Circumventricular organs that information neurally to other brain regions. Through their neural circuitry, they provide direct information to the autonomic nervous system from the systemic circulation. The secretory organs include the subcommissural organ (SCO), the pituitary gland, the median eminence, and the pineal gland. These organs are responsible for secreting hormones and glycoproteins into the peripheral blood using feedback from both the brain environment and external stimuli. All of the circumventricular organs, except the subcommissural organ, contain extensive vasculature and permeable capillaries which define a sensory and secretory system within the brain. Furthermore, all CVOs contain neural tissue, enabling a neuroendocrine role.