Lauryldimethylamine oxide Lauryldimethylamine oxide Lauryldimethylamine oxide (LDAO), also known as dodecyldimethylamine oxide (DDAO), is an amine oxide based nonionic surfactant, with a C (dodecyl) alkyl tail. It is one of the most frequently-used surfactants of this type. Like other amine oxide based surfactants it is antimicrobial, being effective against common bacteria such as "S. aureus" and "E. coli", however it is also non-denaturing and may be used to solubilize proteins. At high concentrations, DDAO forms liquid crystalline phases. Despite having only one polar atom that is able to interact with water – the oxygen atom (the quaternary nitrogen atom is hidden from
Biological functions of nitric oxide dilates the pulmonary vasculature and, because of efficient scavenging by hemoglobin, has minimal effect on the vasculature of the entire body. Inhaled nitric oxide appears to increase the partial pressure of arterial oxygen (PO) by dilating pulmonary vessels in better-ventilated areas of the lung, moving pulmonary blood flow away from lung segments with low ventilation/perfusion (V/Q) ratios toward segments with normal or better ratios. Nitric oxide is absorbed systemically after inhalation. Most of it moves across the pulmonary capillary bed where it combines with hemoglobin that is 60% to 100% oxygen-saturated. Nitrate has been identified as the predominant nitric oxide