Extreme Ghostbusters Extreme Ghostbusters Extreme Ghostbusters is an American animated television series and a follow-up to the animated series "The Real Ghostbusters". It is a part of the "Ghostbusters" franchise. The series originally aired in late 1997, and features a team of younger college-level Ghostbusters who are led by veteran Ghostbuster Egon Spengler. In some TV listings, the show was called "Ghostbusters Dark". Set years after the end of "The Real Ghostbusters", lack of supernatural activity has put the Ghostbusters out of business. Each member has gone their separate way, except for Dr. Egon Spengler, who still lives in the firehouse to
Pictet–Spengler reaction imine generated from the condensation of the aldehyde and amine. This helps to explain the need for an acidic medium in some substrates, as the imine may not be electrophilic enough for ring closure to occur but the Iminium ion is capable of undergoing the reaction. The Pictet-Spengler reaction is widespread in both human industry and biosynthesis. It has remained an important reaction in the fields of alkaloid and pharmaceutical synthesis since its inception, where it has been employed in the development of many beta-carbolines. The enzyme strictosidine synthase is an example of nature utilizing the Pictet-Spengler reaction, which generates