Egon Spengler does not have much social ability, as demonstrated by his stiff interactions with the Ghostbusters' secretary Janine Melnitz, and his reliance on Peter Venkman as spokesperson for the group. Spengler is the most serious and rigid member of the team. Of his hobbies, Spengler states that he collects "spores, molds, and fungus", and claims that, as a child, the only toy he ever had was "part of a Slinky", which he straightened out. As implied in the first movie, Spengler apparently is a sugar junkie, due to his affection for sweets and candy. According to the 2009 video game, Spengler
Pictet–Spengler reaction hydrochloric acid forming a tetrahydroisoquinoline. Like the Mannich reaction, aldehydes give good yields while ketones tend to give lower conversion. The Pictet–Spengler reaction has been applied to solid-phase combinatorial chemistry with great success. An analogous reaction with an aryl-β-ethanol is called Oxa-Pictet–Spengler reaction The reaction mechanism occurs by initial formation of an iminium ion (2) followed by electrophilic addition at the 3-position, in accordance with the expected nucleophilicity of indoles, to give the spirocycle 3. After migration of the best migrating group, deprotonation gives the product (5). Replacing an indole with a 3,4-dimethoxyphenyl group give the reaction named the Pictet–Spengler