International Society of Nephrology International Society of Nephrology The International Society of Nephrology (ISN) is an international body representing specialists in nephrology (kidney diseases). Its headquarters are located in Brussels, Belgium and New Jersey, United States. Since its foundation in 1960, the ISN has pursued the worldwide advancement of education, science and patient care in nephrology, the medical subspecialty dealing with the Kidneys). The Society represents a wide international network and provides an efficient platform for timely scientific exchange, debate and dissemination between healthcare professionals around the world. It is also dedicated to addressing the disparity between the developing and developed worlds in the
Circumventricular organs is also hypothesized that the VOLT may be the mechanism through which pyrogens function to initiate a febrile response in the CNS. Finally, VOLT neurons have been observed to respond to temperature changes indicating that the organum vasculosum of the lamina terminalis is subject to different climates. The subfornical organ is a sensory CVO situated in the lamina terminalis and lacking the BBB, the absence of which characterizes the circumventricular organs. Protruding into the third ventricle of the brain, the highly vascularized SFO can be divided into 3–4 anatomical zones, especially by its capillary density and structure. The central zone