Egon Spengler Egon Spengler Egon Spengler, PhD is a fictional character from the "Ghostbusters" franchise. He appears in the films "Ghostbusters" and "Ghostbusters II", in the animated television series "The Real Ghostbusters" and "Extreme Ghostbusters", in the video games "" and Beeline's "Ghostbusters". Spengler was portrayed by Harold Ramis in the films and voiced by him in "" and "Lego Dimensions", and voiced by Maurice LaMarche in the cartoon series. He is a member of the Ghostbusters and one of the three doctors of parapsychology, along with Dr. Peter Venkman and Dr. Ray Stantz. The character of Egon Spengler was named after
Pictet–Spengler reaction amination. The benzyl group can be removed hydrogenolytically afterwards. As a rough rule, C NMR signals for C1 and C3 are downfield shifted in "cis" products relative to "trans" products (see steric compression effect). Pictet–Spengler reaction The Pictet–Spengler reaction is a chemical reaction in which a β-arylethylamine undergoes condensation with an aldehyde or ketone followed by ring closure. The reaction was first discovered in 1911 by Amé Pictet and Theodor Spengler. Traditionally an acidic catalyst in protic solvent was employed with heating, however the reaction has been shown to work in aprotic media without acid catalysis in superior yields for