Simon Thomas (presenter) 2:1 BA Hons degree in history. Having applied for the job three times, Thomas began presenting the children's programme "Blue Peter" on 8 January 1999 replacing the sacked presenter Richard Bacon. Previously he had worked as a runner at Children's BBC and the radio station LBC. During his tenure at "Blue Peter", he ran in the London Marathon twice and two Great North Runs, climbed Mount Kilimanjaro and Mont Blanc, completed over 40 solo sky dives with the Royal Air Force, presented a medal at the Commonwealth Games, ran in the 60 metres sprint at the Norwich Union Indoor Athletics
Epigenetics of cocaine addiction concluded that ΔFosB, CREB, Sirt1 and Sirt2 all play an integral role in cocaine-seeking behaviors. Kumar et al. focused on how acute and chronic cocaine exposure affected the striatum, which is another area of the brain involved in the reward and locomotor pathways. To study the molecular actions of cocaine in this region, researchers studied the histone modifications of three different promoters: "cFos", "BDNF", and "Cdk5". They saw that "cFos", which is normally expressed immediately after neurons fire action potentials, had high levels of H4 acetylation within 30 minutes of a cocaine injection – but no histone modifications were seen