Roman metallurgy the most important being bronze, an alloy of copper and tin. Alloys are mixtures of different metals created either by smelting or by forging. It is important to note that an ore does not necessarily constitute an alloy; ore is a collection of minerals and alloyed metals. As metallurgical technology developed (hammering, melting, smelting, roasting, cupellation, moulding, smithing, etc.), more metals were intentionally included in the metallurgical repertoire. By the height of the Roman Empire, metals in use included: Gold, Silver, Copper, Tin, Lead, Zinc, Iron, Mercury, Arsenic, Antimony (Healy 1978). As in the Bronze Age, metals were used based
Antimicrobial copper-alloy touch surfaces in rooms with copper touch surfaces were significantly lower than in rooms without copper surfaces. "Staphylococci" were the most predominant microorganism isolated and copper was effective in reducing the "Staphylococci" microbial burden. Further studies regarding the clinical implications of copper's intrinsic ability to reduce microbial burdens in hospitals are being planned. Researchers from the Kitasato University School of Medicine conducted antimicrobial studies of "S. aureus", "E. coli", and "P. aeruginosa" on various Japanese copper alloy coins and on copper alloy plates. The microbes were strains from hospital environments. Copper and its nickel-silver, cupronickel, and brass alloys were found to kill