Tin sources and trade in ancient times shapes cast in closed molds of the Bronze Age. Arsenical bronze objects appear first in the Middle East where arsenic is commonly found in association with copper ore, but the health risks were quickly realized and the quest for sources of the much less hazardous tin ores began early in the Bronze Age . This created the demand for rare tin metal and formed a trade network that linked the distant sources of tin to the markets of Bronze Age cultures. Cassiterite (SnO), oxidized tin, most likely was the original source of tin in ancient times. Other forms of tin
Antimicrobial copper-alloy touch surfaces surfaces typically manufactured with standard materials (i.e., plastic, chrome, aluminum) were replaced with copper alloys. These included a copper alloy set of sink tap handles (60% Cu, 40% Zn) and a ward entrance door push plate (70% Cu, 30% Zn). Contamination reductions of 90–100% were observed for "Staphylococcus aureus", "Escherichia coli", "Klebsiella pneumoniae", "Acinetobacter baumanii", "Enterococcus" spp., and "Candida albicans" on the copper alloy surfaces versus the non-copper standard surfaces. A microorganism reduction of 100% was observed on the hot tap copper alloy handle. The high degree of clinical performance suggested that copper alloy surfaces may increase the effectiveness of