Egon Spengler Egon Spengler Egon Spengler, PhD is a fictional character from the "Ghostbusters" franchise. He appears in the films "Ghostbusters" and "Ghostbusters II", in the animated television series "The Real Ghostbusters" and "Extreme Ghostbusters", in the video games "" and Beeline's "Ghostbusters". Spengler was portrayed by Harold Ramis in the films and voiced by him in "" and "Lego Dimensions", and voiced by Maurice LaMarche in the cartoon series. He is a member of the Ghostbusters and one of the three doctors of parapsychology, along with Dr. Peter Venkman and Dr. Ray Stantz. The character of Egon Spengler was named after
Pictet–Spengler reaction is created. Several substrate- or auxiliary-controlled diastereoselective Pictet–Spengler reactions have been developed. Additionally, List "et al." have published a chiral Brønsted acid that catalyzes asymmetric Pictet–Spengler reactions. Tryptophans: diastereocontrolled reaction The reaction of enantiopure tryptophan or its short-chain alkylesters leads to 1,2,3,4-tetrahydro-"β"-carbolines in which a new chiral center at C-1 adopts either a "cis" or "trans" configuration towards the C-3 carboxyl group. The "cis" conduction is kinetically controlled, i.e. it is performed at lower temperatures. At higher temperatures the reaction becomes reversible and usually favours racemisation. 1,3-"trans" dominated products can be obtained with "N"-benzylated tryptophans, which are accessible by reductive