Extreme Ghostbusters Extreme Ghostbusters Extreme Ghostbusters is an American animated television series and a follow-up to the animated series "The Real Ghostbusters". It is a part of the "Ghostbusters" franchise. The series originally aired in late 1997, and features a team of younger college-level Ghostbusters who are led by veteran Ghostbuster Egon Spengler. In some TV listings, the show was called "Ghostbusters Dark". Set years after the end of "The Real Ghostbusters", lack of supernatural activity has put the Ghostbusters out of business. Each member has gone their separate way, except for Dr. Egon Spengler, who still lives in the firehouse to
Pictet–Spengler reaction is created. Several substrate- or auxiliary-controlled diastereoselective Pictet–Spengler reactions have been developed. Additionally, List "et al." have published a chiral Brønsted acid that catalyzes asymmetric Pictet–Spengler reactions. Tryptophans: diastereocontrolled reaction The reaction of enantiopure tryptophan or its short-chain alkylesters leads to 1,2,3,4-tetrahydro-"β"-carbolines in which a new chiral center at C-1 adopts either a "cis" or "trans" configuration towards the C-3 carboxyl group. The "cis" conduction is kinetically controlled, i.e. it is performed at lower temperatures. At higher temperatures the reaction becomes reversible and usually favours racemisation. 1,3-"trans" dominated products can be obtained with "N"-benzylated tryptophans, which are accessible by reductive