Extreme Ghostbusters Extreme Ghostbusters Extreme Ghostbusters is an American animated television series and a follow-up to the animated series "The Real Ghostbusters". It is a part of the "Ghostbusters" franchise. The series originally aired in late 1997, and features a team of younger college-level Ghostbusters who are led by veteran Ghostbuster Egon Spengler. In some TV listings, the show was called "Ghostbusters Dark". Set years after the end of "The Real Ghostbusters", lack of supernatural activity has put the Ghostbusters out of business. Each member has gone their separate way, except for Dr. Egon Spengler, who still lives in the firehouse to
Pictet–Spengler reaction amination. The benzyl group can be removed hydrogenolytically afterwards. As a rough rule, C NMR signals for C1 and C3 are downfield shifted in "cis" products relative to "trans" products (see steric compression effect). Pictet–Spengler reaction The Pictet–Spengler reaction is a chemical reaction in which a β-arylethylamine undergoes condensation with an aldehyde or ketone followed by ring closure. The reaction was first discovered in 1911 by Amé Pictet and Theodor Spengler. Traditionally an acidic catalyst in protic solvent was employed with heating, however the reaction has been shown to work in aprotic media without acid catalysis in superior yields for