Andy Murray in round two of the Rome Masters by qualifier Juan Mónaco, and he reached the quarter-finals of the Madrid Masters, losing to Juan Martín del Potro. During this time Murray achieved the highest ever ranking of a British male in the Open Era when he reached the No. 3 ranking on 11 May 2009. Murray reached the quarter-finals of the French Open, but was defeated by Fernando González in four sets. Murray won for the first time on grass at Queen's and became the first British winner of the tournament since 1938. In the final Murray defeated American James Blake.
Andy Murray Ranked No. 312, Murray became the first Scot in the Open Era to reach the third round of the men's singles tournament at Wimbledon. In the third round, Murray lost to 2002 Wimbledon finalist David Nalbandian due to cramping and fatigue, having led two sets to love. Following Wimbledon, Murray won Challenger events on the hard courts of Aptos and Binghamton, New York. He then experienced his first Masters event at Cincinnati, where he beat Taylor Dent, before losing in three sets to then-No. 4, Marat Safin. With a wild card entry, Murray played Andrei Pavel in the opening round