Arsenic and Old Lace (play) Arsenic and Old Lace (play) Arsenic and Old Lace is a play by American playwright Joseph Kesselring, written in 1939. It has become best known through the subsequent film adaptation starring Cary Grant and directed by Frank Capra. The play was directed by Bretaigne Windust, and opened on Broadway at the Fulton Theatre on January 10, 1941. On September 25, 1943, the play moved to the Hudson Theatre. It closed there on June 17, 1944, having played 1,444 performances. Of the twelve plays written by Kesselring, "Arsenic and Old Lace" was the most successful, and, according to the opening night
Eps-Associated RNA element reconstitute EAR-mediated processive antitermination mechanism "in vitro" or in a Gram-negative heterologous host ("E. coli"), suggesting that additional "B. subtilis"-specific factor(s) may also be required for EAR antitermination. Eps-Associated RNA element The "eps"-Associated RNA element (EAR; also called "epsC" motif) is a conserved RNA motif associated with exopolysaccharide ("eps") or capsule biosynthesis genes in a subset of bacteria classified within the order Bacillales. It was initially discovered in "Bacillus subtilis", located between the second and third gene in the "eps" operon (i.e., between "epsB" and "epsC"). Deletion of the EAR element impairs biofilm formation. The combination of comparative sequence alignments