Egon Spengler fraud, violating their judicial restraining order, and malicious mischief by judge Stephen Wexler (whom Egon said was known as "The Hammer"). While angrily insulting the trio judge Wexler inadvertently released the ghosts of the Scoleri Brothers; two murderers he sentenced to death by the electric chair. During the chaos judge Wexler dismisses the charges against the Ghostbusters, and rescinds the judicial restraining order allowing Egon, Ray, and Peter to capture the ghosts, effectively putting the Ghostbusters back in business. Egon had a dry sense of humor, of which he used on Peter to bewilder him, and smirked at his friend's
Pictet–Spengler reaction imine generated from the condensation of the aldehyde and amine. This helps to explain the need for an acidic medium in some substrates, as the imine may not be electrophilic enough for ring closure to occur but the Iminium ion is capable of undergoing the reaction. The Pictet-Spengler reaction is widespread in both human industry and biosynthesis. It has remained an important reaction in the fields of alkaloid and pharmaceutical synthesis since its inception, where it has been employed in the development of many beta-carbolines. The enzyme strictosidine synthase is an example of nature utilizing the Pictet-Spengler reaction, which generates