Gimlet (cocktail) A similar lime juice cocktail using rum instead of vodka or gin is the daiquiri. David A. Embury gave a gimlet recipe (called a Gin Sour) in "The Fine Art of Mixing Drinks" (3rd Ed., 1958), calling for an 8:2:1 gin/lime (or lemon) juice/simple syrup ratio plus garnish. Eric Felten essentially repeated this in his "How's Your Drink" column in "The Wall Street Journal" Weekend Edition of August 4, 2006: William L. Hamilton gave this recipe in his "Shaken and Stirred" column in "The New York Times" on September 15, 2002: A gimlet served at the Fifty Seven Fifty Seven
Cooperstown cocktail Cooperstown cocktail The Cooperstown cocktail refers to a panel of four drug probes used in human pharmacokinetic studies to determine the activity of drug metabolising enzymes. The terminology 'cocktail' refers to the fact that the drug probes are given together. The Cooperstown cocktail consists of four drugs that are considered specific substrates for four cytochrome P450 (CYP) isoforms. One of the drugs (caffeine) provides, through its metabolites, substrates for two additional enzymes (see next paragraph). The drugs and the enzymes they probe are as follows - caffeine (probes CYP1A2, N-acetyltransferase 2, xanthine oxidase), midazolam (probes CYP3A), omeprazole (probes CYP2C19) and