Egon Spengler portraying the character other than to follow Ramis's example. He got the part anyway and said in an interview that he did two different takes: in which he impersonated Ramis, the other in which he tried a more "Woody Allen"-like approach that did not suit the character's physicality, he admitted. Egon Spengler is a tall, laconic, bespectacled, awkward member of the team responsible for the main theoretical framework for their paranormal/quantum studies. Being addicted to science, he is the creator of the Ghostbusters' equipment along with Raymond Stantz, thus making him the brains of the Ghostbusters. Although book smart, Spengler
Pictet–Spengler reaction Pictet–Spengler reaction The Pictet–Spengler reaction is a chemical reaction in which a β-arylethylamine undergoes condensation with an aldehyde or ketone followed by ring closure. The reaction was first discovered in 1911 by Amé Pictet and Theodor Spengler. Traditionally an acidic catalyst in protic solvent was employed with heating, however the reaction has been shown to work in aprotic media without acid catalysis in superior yields for a variety of cases. The Pictet–Spengler reaction can be considered a special case of the Mannich reaction, which follows a similar reaction pathway. The driving force for this reaction is the electrophilicity of the