International Society of Nephrology research, diagnosis, treatment, and prevention of kidney disease. The ISN has over 9,000 professional members from more than 126 countries. In addition, the ISN closely collaborates with over 75 national and regional nephrology societies around the world, representing about 20,000 professionals. The ISN continues to develop and consolidate several programs, initiatives and partnerships that will help to further deliver on its two overarching goals: reducing the incidence and impact of kidney disease worldwide, and making the ISN the leading international organization for all issues related to the science and practice of global nephrology. In 1992 the society formed a task
Circumventricular organs isoleucine, calcitonin gene-related peptide, substance P and somastotin. However, these probably accumulate in the pineal but are not produced by the gland itself. Circumventricular organs Circumventricular organs (CVOs) are structures in the brain characterized by their extensive and highly permeable microvasculature, unlike those in the rest of the brain where there exists a blood brain barrier (BBB). The term "circumventricular organs" was originally proposed in 1958 by Austrian anatomist Helmut Hofer, in recognition of the distribution of the structures around the ventricular system of the brain. The circumventricular organs are midline structures around the third and fourth ventricles that are