Simon Thomas (presenter) 2:1 BA Hons degree in history. Having applied for the job three times, Thomas began presenting the children's programme "Blue Peter" on 8 January 1999 replacing the sacked presenter Richard Bacon. Previously he had worked as a runner at Children's BBC and the radio station LBC. During his tenure at "Blue Peter", he ran in the London Marathon twice and two Great North Runs, climbed Mount Kilimanjaro and Mont Blanc, completed over 40 solo sky dives with the Royal Air Force, presented a medal at the Commonwealth Games, ran in the 60 metres sprint at the Norwich Union Indoor Athletics
Epigenetics of cocaine addiction of cocaine. Conversely, an increase of CREB was shown to decrease the rewarding effects of cocaine. Zhang et al. also used microarrays to identify specific genes induced by chronic cocaine use, which depend on a functional D1 receptor 24 hours after cocaine withdrawal. There were 109 genes identified that were either up or down regulated by 1.2 fold or more in the caudate putamen D1 receptor mutant mice after repeat injections. The expression of these genes was totally normal in mice with functional D1 receptors, suggesting chronic cocaine use had a direct influence on mediating these genes through a functional