Alice Catherine Evans service worker was protected by law. Alice became interested in the disease brucellosis and its relationship to fresh, unpasteurized milk. Alice's investigation focused on the organism "Bacillus abortus", known to cause miscarriages in animals. Alice learned that the microbe thrived in infected cows as well as animals that appeared healthy. The reports hypothesized that since the bacteria was found in cow's milk, a threat to human health was likely. Evans decided to investigate this; she wondered whether the disease in cows could be the cause of undulant fever in humans. She reported her findings to the Society of American Bacteriologists
Brucellosis followed up serologically for six months. Recently published experience confirms that prolonged and frequent serological follow-up consumes significant resources without yielding much information, and is burdensome for the affected staff, who often fail to comply. The side effects of the usual recommended regimen of rifampicin and doxycycline for three weeks also reduce treatment adherence. As no evidence shows treatment with two drugs is superior to monotherapy, British guidelines now recommend doxycycline alone for three weeks and a less onerous follow-up protocol. Under the name "Malta fever", the disease now called brucellosis first came to the attention of British medical officers