Callisto (moon) facilitate remote exploration of Europa, or be an ideal location for a Jovian system waystation servicing spacecraft heading farther into the outer Solar System, using a gravity assist from a close flyby of Jupiter after departing Callisto. In December 2003, NASA reported that a manned mission to Callisto might be possible in the 2040s. Callisto (moon) </math>.</ref> Callisto (Jupiter IV) is the second-largest moon of Jupiter, after Ganymede. It is the third-largest moon in the Solar System after Ganymede and Saturn's largest moon Titan, and the largest object in the Solar System not to be properly differentiated. Callisto was discovered
Planet Nine cause the orbits of the other planets to precess, similar to but slower than the eTNOs, covering short arcs over the lifetime of the Solar System. These observations are consistent with the Planet Nine hypothesis but do not prove that Planet Nine exists as there are other potential explanations for the spin–orbit misalignment of the Solar System. Batygin was cautious in interpreting the results of the simulation developed for his and Brown's research article, saying, "Until Planet Nine is caught on camera it does not count as being real. All we have now is an echo." Brown put the odds