Culture of the United Kingdom battleship the "Bismarck" in May 1941. In 1952, "OXO" (or "Noughts and Crosses"), created by computer scientist Alexander S. Douglas, is regarded as a contender for the first video game. In "OXO", the computer player could play perfect games of tic-tac-toe against a human opponent. In the 1960s, John Shepherd-Barron invented the cash machine (ATM) and James Goodfellow invented Personal identification number (PIN) technology, and on 27 June 1967, the first cash machine was established outside a branch of Barclays Bank in Enfield, north London. Dolly the sheep, the first mammal successfully cloned from an adult somatic cell (by scientists
Cloned enzyme donor immunoassay enzyme activity. Cloned enzyme donor immunoassay A cloned enzyme donor immunoassay (CEDIA) is a competitive homogenous enzyme immunoassay. This assay makes use of two component fragments of an enzyme which are each individually inactive. Under the right conditions in solution these fragments can spontaneously reassemble to form the active enzyme. For use in biochemical assays one of the enzyme fragments is attached to an analyte of interest. The analyte-enzyme-fragment-conjugate is still able to reassemble with the other enzyme fragment to form an active enzyme. However it is unable to do this if the analyte is bound to an antibody. To