In Re Roslin Institute (Edinburgh) In Re Roslin Institute (Edinburgh) In re Roslin Institute (Edinburgh), 750 F.3d 1333 (Fed. Cir. 2014), is a 2014 decision of the United States Court of Appeals for the Federal Circuit rejecting a patent for a cloned sheep known as "Dolly the Sheep"— the first mammal ever cloned from an adult somatic cell. Dolly was cloned in 1996 by Ian Wilmut, Keith Campbell and colleagues at the Roslin Institute, part of the University of Edinburgh Scotland. BBC News and Scientific American called Dolly "the world's most famous sheep," The cloning method Campbell and Wilmut used to create Dolly constituted a
Cloned enzyme donor immunoassay Cloned enzyme donor immunoassay A cloned enzyme donor immunoassay (CEDIA) is a competitive homogenous enzyme immunoassay. This assay makes use of two component fragments of an enzyme which are each individually inactive. Under the right conditions in solution these fragments can spontaneously reassemble to form the active enzyme. For use in biochemical assays one of the enzyme fragments is attached to an analyte of interest. The analyte-enzyme-fragment-conjugate is still able to reassemble with the other enzyme fragment to form an active enzyme. However it is unable to do this if the analyte is bound to an antibody. To determine the