Yellowstone Park bison herd a highly contagious zoonosis caused by ingestion of unpasteurized milk or undercooked meat from infected animals, or close contact with their secretions. Brucellosis occurs naturally in the Yellowstone Bison Herd and the normal winter migrations of bison outside the park have raised concerns that Brucellosis infected Bison may infect cattle. The United States government has programs to eradicate brucellosis in domestic livestock. Since 1934, an estimated $3.5 billion in federal, state, and private funds has been spent on brucellosis eradication in domestic livestock. Over the years, the National Park Service and states bordering the park have implemented various plans to
Brucellosis aminoglycosides streptomycin and gentamicin are effective against "Brucella" bacteria. However, the use of more than one antibiotic is needed for several weeks, because the bacteria incubate within cells. Surveillance using serological tests, as well as tests on milk like the milk ring test, can be used for screening and play an important role in campaigns to eliminate the disease. Also, individual animal testing both for trade and for disease-control purposes is practiced. In endemic areas, vaccination is often used to reduce the incidence of infection. An animal vaccine is available that uses modified live bacteria. The World Organisation for Animal