Roslin Institute campus of the University, but despite this, retained its now world famous name. The Institute won international fame in 1996, when Ian Wilmut, Keith Campbell and their colleagues created Dolly the sheep, the first mammal to be cloned from an adult cell, at the institute. A year later Polly and Molly were cloned, both sheep contained a human gene. Roslin has made many other contributions to animal sciences, especially in the area of livestock improvement and welfare through applications of Quantitative Genetics. In 2007 a Roslin team developed genetically modified chickens capable of laying eggs containing proteins needed to make
Cloned enzyme donor immunoassay enzyme activity. Cloned enzyme donor immunoassay A cloned enzyme donor immunoassay (CEDIA) is a competitive homogenous enzyme immunoassay. This assay makes use of two component fragments of an enzyme which are each individually inactive. Under the right conditions in solution these fragments can spontaneously reassemble to form the active enzyme. For use in biochemical assays one of the enzyme fragments is attached to an analyte of interest. The analyte-enzyme-fragment-conjugate is still able to reassemble with the other enzyme fragment to form an active enzyme. However it is unable to do this if the analyte is bound to an antibody. To