The General in His Labyrinth explores the labyrinth of Bolívar's life through the narrative of his memories, in which "despair, sickness, and death inevitably win out over love, health, and life". Following the success of "One Hundred Years of Solitude" and "Love in the Time of Cholera", García Márquez decided to write about the "Great Liberator" after reading an unfinished novel by his friend Álvaro Mutis. He borrowed the setting—Bolívar's voyage down the Magdalena River in 1830—from Mutis. García Márquez spent two years researching the subject, encompassing the extensive memoirs of Bolívar's Irish aide-de-camp, Daniel Florencio O'Leary, as well as numerous other historical documents and
Love in the Time of Cholera metaphorical plague is another manifestation of this. The term cholera as it is used in Spanish, , can also denote passion or human rage and ire in its feminine form. (The English adjective has the same meaning.) Considering this meaning, the title is a pun: cholera as the disease, and cholera as passion, which raises the central question of the book: is love helped or hindered by extreme passion? The two men can be contrasted as the extremes of passion: one having too much, one too little; the central question of which is more conducive to love and happiness becomes