United States raw milk debate systematic review of the food safety of unpasteurized milk concluded that science-based data to substantiate claims of health benefits "are lacking or do not exist" and the risks associated with disease outbreaks as a result of raw milk consumption are "considerably higher". Pasteurization was first used in the United States in the 1890s after the discovery of germ theory to control the hazards of highly contagious bacterial diseases, including bovine tuberculosis and brucellosis, that could be easily transmitted to humans through the drinking of raw milk. Initially after the scientific discovery of bacteria, no product testing was available to determine
Swine brucellosis Swine also develop orchitis (swelling of the testicles), lameness (movement disability), hind limb paralysis, or spondylitis (inflammation in joints). Because "B. suis" is facultative and intracellular, and is able to adapt to environmental conditions in macrophages, treatment failure and relapse rates are high. The only effective way to control and eradicate zoonosis is by vaccination of all susceptible hosts and elimination of infected animals. The "Brucella abortus" (rough LPS "Brucella") vaccine, developed for bovine brucellosis and licensed by the USDA Animal Plant Health Inspection Service, has shown protection for some swine and is also effective against "B. suis" infection, but