Sheep ideal research subjects, and thus are not a common model organism. They have, however, played an influential role in some fields of science. In particular, the Roslin Institute of Edinburgh, Scotland used sheep for genetics research that produced groundbreaking results. In 1995, two ewes named Megan and Morag were the first mammals cloned from differentiated cells. A year later, a Finnish Dorset sheep named Dolly, dubbed "the world's most famous sheep" in "Scientific American", was the first mammal to be cloned from an adult somatic cell. Following this, Polly and Molly were the first mammals to be simultaneously cloned and
Royana (cloned sheep) uterus of a female sheep. After a period of 145 days, Royana was born by caesarean section. Despite critical conditions, he survived and thrived. Royana was born on April 15, 2006, 1:30 am at Isfahan campus of Royan Institute by cesarean section in a healthy condition. Royana was euthanized after the abdominal pain was traced to his liver. It was also thought that Royana suffered premature death syndrome. Royana died at the age of three. His birth was a great step in the production of transgenic lambs containing factor IX transgenic, which is helpful in human blood clotting. Royana (cloned