Edward Jenner humans a cowpox vaccine against smallpox. For example, Dorset farmer Benjamin Jesty successfully vaccinated and presumably induced immunity with cowpox in his wife and two children during a smallpox epidemic in 1774, but it was not until Jenner's work that the procedure became widely understood. Jenner may have been aware of Jesty's procedures and success. A similar observation had also been made in France by Jacques Antoine Rabaut-Pommier in 1780. Noting the common observation that milkmaids were generally immune to smallpox, Jenner postulated that the pus in the blisters that milkmaids received from cowpox (a disease similar to smallpox, but
Royal Edward (1796 ship) Citations References Royal Edward (1796 ship) Royal Edward was launched in 1782 in France as "Alexandre". The British captured her c.1796, and new owners changed her name. She then sailed for a few years as a West Indiaman before completing four voyages as a slave ship. She returned to the West India trade after leaving the slave trade, and then traded more generally. She was condemned as unseaworthy and broken up in Bengal in 1815. "Royal Edward" was launched in 1782, in France, as "Alexandre". She was reportedly a prize to . "Alexandre" was condemned in Prize Court and sold.