Charles Harrison Blackley Charles Harrison Blackley Charles Harrison Blackley (5 April 1820 – 4 September 1900) was the discoverer of the mechanism behind allergic rhinitis caused by pollen, commonly called hay fever. The isolation of hay fever as a condition had been known since 1819 through the work of John Bostock. Blackley was the first to connect pollen to the condition, and though he held some later discredited views, his insight was an important step in the research of allergens. His most important work was a book titled the "Experimental Researches on the Causes and Nature of Catarrhus aestivus", published in 1873. Charles
Allergic bronchopulmonary aspergillosis Allergic bronchopulmonary aspergillosis Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterised by an exaggerated response of the immune system (a hypersensitivity response) to the fungus "Aspergillus" (most commonly "Aspergillus fumigatus"). It occurs most often in people with asthma or cystic fibrosis. "Aspergillus" spores are ubiquitous in soil and are commonly found in the sputum of healthy individuals. "A. fumigatus" is responsible for a spectrum of lung diseases known as aspergilloses. ABPA causes airway inflammation, leading to bronchiectasis—a condition marked by abnormal dilation of the airways. Left untreated, the immune system and fungal spores can damage sensitive lung tissues and lead