Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Valentine S. Keppel Valentine S. Keppel Valentine S. "V.S." "Val" Keppel (February 21, 1865 – September 7, 1940) was an American farmer and politician. Born in La Crosse County, Wisconsin in Mormon Coulee, Keppel went to the public schools. He was a farmer and lived in Long Coulee near Holmen, Wisconsin. He was the manager and secretary of the Holmen Cooperative Creamery and was also secretary of the Holmen Telephone Company. Keppel was also one of the directors of the Holmen Bank. Keppel was a supporter of United States Senator Robert M. La Follette, Sr. and the Wisconsin Progressive Party. Keppel served on