Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Valentine S. Keppel the grade school and high school board. He also served on the La Crosse County Board and was chairman of the county board. During World War I, Keppel served on the local draft board. From 1907 to 1909, Keppel served in the Wisconsin State Assembly. Then, from 1925 to 1933, Keppel served in the Wisconsin State Senate and was a Republican. Keppel died in Holmen, Wisconsin as a result of a stroke. Valentine S. Keppel Valentine S. "V.S." "Val" Keppel (February 21, 1865 – September 7, 1940) was an American farmer and politician. Born in La Crosse County, Wisconsin in