Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Valentine S. McClatchy for Mexicans to gain a classification of their race to ensure they would not be able to be exempt from the 1924 Immigration Act. In 1937, he lobbied to strip Kibei, Japanese Americans born in the United States who were sent to Japan to study or visit family for an extended time, of their citizenship if they had been in Japan for more than a year. He died of a heart condition on May 15, 1938. Valentine S. McClatchy Valentine Stuart McClatchy (August 29, 1857 – May 15, 1938) was an American newspaper owner and journalist. As publisher of "The