Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
HMS Valentine (L69) transferring to Dover Command in May. "Valentine" was one of four destroyers deployed to the Scheldt estuary to support demolition operations and the evacuation of shipping from Antwerp. While providing AA cover to Allied troops, "Valentine" was damaged by dive bombers on 15 May 1940, and beached near Terneuzen. 31 of "Valentine"s crew were killed, with a further 21 injured. "Valentine" was partly salvaged and broken up in 1953, but part of the ship's hull remains and is sometimes visible at low tide. HMS Valentine (L69) HMS "Valentine" was a , built in 1917 for the Royal Navy. She fought