Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Perfect Day (1929 film) Perfect Day (1929 film) Perfect Day is a 1929 short comedy film starring Laurel and Hardy. Two families embark on a pleasant Sunday picnic in their Ford Model T, but manage to run into a variety of issues with the temperamental automobile. Each incident requires repeated exits and reboardings by Laurel, Hardy, their wives and grouchy, gout-ridden Uncle Edgar. A brick-throwing argument with a neighbor threatens to escalate into an all-out turf war until the local parson gets involved. The families manage to finally get their day underway, only to plunge neck-deep into a seemingly shallow, water-filled pothole. "Perfect Day"