Edward Jenner humans a cowpox vaccine against smallpox. For example, Dorset farmer Benjamin Jesty successfully vaccinated and presumably induced immunity with cowpox in his wife and two children during a smallpox epidemic in 1774, but it was not until Jenner's work that the procedure became widely understood. Jenner may have been aware of Jesty's procedures and success. A similar observation had also been made in France by Jacques Antoine Rabaut-Pommier in 1780. Noting the common observation that milkmaids were generally immune to smallpox, Jenner postulated that the pus in the blisters that milkmaids received from cowpox (a disease similar to smallpox, but
Kendall Jenner two signature nail lacquers for the 2011 Nicole by OPI Kardashian Kolors nail polish line, for which the Jenner sisters eventually earned a combined in endorsement profit. On March 16, 2012, the Jenner sisters were named Creative Directors of the "Gillette Venus Gets Ready with Kendall & Kylie Jenner" webisode series, which was originally aired on Gillette's Facebook page. In July 2013, the Jenner sisters formed a partnership with Pascal Mouawad's Glamhouse to create the "Metal Haven by Kendall & Kylie" jewelry collection. In February 2014, the Jenner sisters launched a shoe and handbag line under Steve Madden's "Madden Girl"