Jenner Township, Somerset County, Pennsylvania named in honor of Dr. Edward Jenner, discoverer of the smallpox vaccine. Early Jenner Township settlers were primarily German and English speakers engaged in agriculture. Pennsylvania Dutch was still spoken in rural parts of the township until the 1960s. Jenner Crossroads, the township's first substantial European settlement, grew near a grist mill and tavern stop established about 1800 along the Pennsylvania Road. Samuel Steel built a sawmill at Jenner Crossroads in 1817; John Shopwood opened a hotel in 1825, and Samuel Elder opened the first store in 1836 Other early industry in the township included a sawmill on Quemahoning Creek
Edward Jenner of the previously misunderstood life of the nested cuckoo, a study that combined observation, experiment, and dissection. He described how the newly hatched cuckoo pushed its host's eggs and fledgling chicks out of the nest (contrary to existing belief that the adult cuckoo did it). Having observed this behaviour, Jenner demonstrated an anatomical adaptation for it—the baby cuckoo has a depression in its back, not present after 12 days of life, that enables it to cup eggs and other chicks. The adult does not remain long enough in the area to perform this task. Jenner's findings were published in "Philosophical