Teresa (Barbie) and sidekick". In Life in the Dreamhouse Barbie states that all girls Teresa, Nikki, Summer, Midge, Raquelle & Grace are all her 'BFFs'. To counteract the criticisms that Barbie was a sex symbol, Mattel was compelled to issue companions for Barbie. Some of these are her boyfriend Ken, the African American Christie, Barbie's cousin Francie and Barbie's little sister Skipper. Midge appeared in 1963 and was marketed as Barbie's first best friend. Midge was discontinued in 1967. Over the years, Barbie's family tree expanded and soon Barbie would have many diverse and multicultural friends. Among these was Teresa, who was
RTS,S which was added a chemical adjuvant (AS01) to increase the immune system response. Infection is prevented by inducing humoral and cellular immunity, with high antibody titers, that block the parasite from infecting the liver. The T-cell epitope of CSP is O-fucosylated in "Plasmodium falciparum" and "Plasmodium vivax", while the RTS,S vaccine produced in yeast is not. RTS,S RTS,S/AS01 — trade name Mosquirix — is a recombinant protein-based malaria vaccine. Approved for use by European regulators in July 2015, it is the world's first licensed malaria vaccine and also the first vaccine licensed for use against a human parasitic disease of