Santa's Little Helper because there were animation problems with the others. Jean told the "Houston Chronicle" in 2001 that after the first episode was broadcast and "the next seven didn't have the dog, people wondered why." He also said in 2003 that the staff enjoyed the first episodes that centered on him, particularly "Simpsons Roasting on an Open Fire", which is the reason that more episodes about him were written. Writer John Swartzwelder has noted that the staff members of the show write the character Homer in the same way that they write Santa's Little Helper: "Both are loyal. Both have the same
T helper 3 cell T helper 3 cell T helper 3 cells (T3) are white blood cells of the lymphocyte type. They are involved in regulating the body's immune response. The function of T helper cells generally is to mediate the immune response by secreting cytokines and interacting with B-cells to enhance or inhibit their activity. This is of particular importance in the gut as this is where the highest load of foreign material, food, is present. T3 cells are involved in mucosal immunity and protecting mucosal surfaces in the gut from non-pathogenic non-self antigens. They mediate this non-inflammatory environment by secreting TGF-β and