Edward Jenner humans a cowpox vaccine against smallpox. For example, Dorset farmer Benjamin Jesty successfully vaccinated and presumably induced immunity with cowpox in his wife and two children during a smallpox epidemic in 1774, but it was not until Jenner's work that the procedure became widely understood. Jenner may have been aware of Jesty's procedures and success. A similar observation had also been made in France by Jacques Antoine Rabaut-Pommier in 1780. Noting the common observation that milkmaids were generally immune to smallpox, Jenner postulated that the pus in the blisters that milkmaids received from cowpox (a disease similar to smallpox, but
Caitlyn Jenner restrict the legal definition of a person's gender to that assigned at birth. Prior to her public gender transition, Jenner had been married three times, first to Chrystie Scott ( Crownover) from 1972 to 1981. They have two children, son Burton "Burt" Jenner and daughter Cassandra "Casey" Marino ( Jenner). Jenner and Scott's divorce was finalized the first week of January 1981. On January 5, 1981, Jenner married actress Linda Thompson in Hawaii. They have two sons together, Brandon Jenner and Sam Brody Jenner (known as Brody). By February 1986, Jenner and Thompson had separated and subsequently divorced. Their sons