Edward Jenner humans a cowpox vaccine against smallpox. For example, Dorset farmer Benjamin Jesty successfully vaccinated and presumably induced immunity with cowpox in his wife and two children during a smallpox epidemic in 1774, but it was not until Jenner's work that the procedure became widely understood. Jenner may have been aware of Jesty's procedures and success. A similar observation had also been made in France by Jacques Antoine Rabaut-Pommier in 1780. Noting the common observation that milkmaids were generally immune to smallpox, Jenner postulated that the pus in the blisters that milkmaids received from cowpox (a disease similar to smallpox, but
Caitlyn Jenner a six-minute film featuring Jenner, called "Caitlyn Jenner's Greatest Victories: A Timeline". In a "20/20" interview with Diane Sawyer in April 2015, Jenner came out as a trans woman, saying that she had dealt with gender dysphoria since her youth and that, "for all intents and purposes, I'm a woman." Jenner cross-dressed for many years and took hormone replacement therapy but stopped after her romance with Kris Kardashian became more serious, leading to marriage in 1992. Jenner recounts having permission to explore her gender identity on her own travels but not when they were coupled, and that not knowing the