Chloropyramine Chloropyramine Chloropyramine is a classical ("old", or first-generation) antihistamine drug approved in some Eastern European countries (like Russia) for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Related indications for clinical use include angioedema (Quincke's edema), allergic reactions to insect bites, food and drug allergies, and anaphylactic shock. Chloropyramine is known as a competitive reversible H receptor antagonist (also known as an H inverse agonist), meaning that it exerts its pharmacological action by competing with histamine for the H subtype histamine receptor. By blocking the effects of histamine, the drug inhibits the vasodilation, increased
Allergic rhinitis positive. The symptoms of allergies resemble those of the common cold; however, they often last for more than two weeks and typically do not include a fever. Exposure to animals in early life might reduce the risk of developing allergies to them later. A number of medications may improve symptoms including nasal steroids, antihistamines such as diphenhydramine, cromolyn sodium, and leukotriene receptor antagonists such as montelukast. Medications are, however, not sufficient or are associated with side effects in many people. Exposing people to larger and larger amounts of allergen, known as allergen immunotherapy, is often effective. The allergen may be