Jenner Township, Somerset County, Pennsylvania named in honor of Dr. Edward Jenner, discoverer of the smallpox vaccine. Early Jenner Township settlers were primarily German and English speakers engaged in agriculture. Pennsylvania Dutch was still spoken in rural parts of the township until the 1960s. Jenner Crossroads, the township's first substantial European settlement, grew near a grist mill and tavern stop established about 1800 along the Pennsylvania Road. Samuel Steel built a sawmill at Jenner Crossroads in 1817; John Shopwood opened a hotel in 1825, and Samuel Elder opened the first store in 1836 Other early industry in the township included a sawmill on Quemahoning Creek
Jenner, California build a house in what became known as Jenner Gulch, the site of the town. Stillwater Cove Regional Park, located north of Jenner, features picnic facilities, beach access, and a historic one-room schoolhouse. Jenner received media attention in 2004 after the bodies of Lindsay Cutshall and Jason S. Allen were discovered on Fish Head Beach just north of town. The incident became known as the Jenner, California double-murder of 2004. According to the United States Census Bureau, the CDP covers an area of 2.4 square miles (6.2 km²), 2.1 square miles (5.5 km²) of it land, and 0.3 square miles