Chloropyramine Chloropyramine Chloropyramine is a classical ("old", or first-generation) antihistamine drug approved in some Eastern European countries (like Russia) for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Related indications for clinical use include angioedema (Quincke's edema), allergic reactions to insect bites, food and drug allergies, and anaphylactic shock. Chloropyramine is known as a competitive reversible H receptor antagonist (also known as an H inverse agonist), meaning that it exerts its pharmacological action by competing with histamine for the H subtype histamine receptor. By blocking the effects of histamine, the drug inhibits the vasodilation, increased
Double Allergic space. Powderfinger spent less money producing "Double Allergic" than on their previous works. Previously, the band had worked with Tony Cohen, whom Fanning stated was expensive due to his success in the industry. For "Double Allergic" the band chose Tim Whitten, a less well known producer, and because the band knew what they intended to do as they entered the studio they managed to spend less despite the improved sound. Middleton commented on Whitten's capabilities in the recording studio, saying "He's what a band looks for in a producer/engineer, because he's got his own ideas", but stating that Whitten would