European colonisation of Southeast Asia tightening Turkish control and eventual shut down of the Eastern Mediterranean gateways into Asia first prompted Portuguese, and later Spanish and Dutch sea voyagers to ship around Africa in search of new trading routes and business opportunities. Niccolò de' Conti arrived in Southeast Asia as the earliest documented European in the early 15th century. By 1498 Vasco da Gama, who had sailed round the Cape of Good Hope, established the first direct sea route from Europe to India. Central among the various plannings was to establish direct and permanent trade of the highly priced spices, that were native to Southeast
Asia–Europe Foundation focusses on economic policy across Asia and Europe, international trade and investment, and global economic challenges. Since its inception, ASEF has initiated several dialogue platforms on sustainable development and climate change issues in Asia and Europe. Reflecting priorities of the ASEM Process as well as the needs of stakeholders at international, regional, and national levels, ASEF’s activities in this field focus on contributing to the implementation of the 2030 Agenda. The ASEF Public Health Network (ASEF PHN) is part of the ASEM Initiative for the Rapid Containment of Pandemic Influenza. The initiative was officially launched in 2009 with the financial