History of penicillin History of penicillin The history of penicillin follows a number of observations and discoveries of apparent evidence of antibiotic activity in molds before the modern isolation of the chemical penicillin in 1928. There are anecdotes about ancient societies using molds to treat infections, and in the following centuries many people observed the inhibition of bacterial growth by various molds. However, it is unknown if the species involved were "Penicillium" species or if the antimicrobial substances produced were penicillin. The Scottish physician Alexander Fleming was the first to suggest that a "Penicillium" mold must secrete an antibacterial substance, and the first
Perfect Day (1929 film) was written in May 1929 and filmed between June 1–8, 1929. The original 1929 release of "Perfect Day" contained no music other than that used over the opening credits. The Roach Studios would reissue the film in 1937 with an added music score being utilized at the time in other Roach comedies. The 1929 version was considered lost until the 2011 DVD release "Laurel and Hardy: The Essential Collection", when the original Vitaphone disc track sans the incidental music became available. Adding the soundtrack in 1937 to the existing film resulted in a slight reduction of the correct frame ratio: