Allergic rhinitis antihistamines like azelastine antihistamine nasal spray, relief from symptoms is experienced within 15 minutes allowing for a more immediate 'as-needed' approach to dosage. There is not enough evidence of antihistamine efficacy as an add-on therapy with nasal steroids in the management of intermittent or persistent allergic rhinitis in children, so its adverse effects and additional costs must be considered. Ophthalmic antihistamines (such as azelastine in eye drop form and ketotifen) are used for conjunctivitis, while intranasal forms are used mainly for sneezing, rhinorrhea, and nasal pruritus. Antihistamine drugs can have undesirable side-effects, the most notable one being drowsiness in the
Seasonal adjustment data can be misleading. This is because the seasonally adjusted series contains both the trend-cycle component and the error component. As such, the seasonally adjusted data will not be "smooth" and what appears to be "downturns" or "upturns" may actually be randomness in the data. For this reason, if the purpose is finding turning points in a series, it is better to use the trend-cycle component rather than the seasonally adjusted data. Seasonal adjustment Seasonal adjustment is a statistical method for removing the seasonal component of a time series that exhibits a seasonal pattern. It is usually done when wanting