Saab 9-3 the standard offering, and a "HOT" (B204R, 200 hp) variant in the SE models for the 1999 model year. The 2000 model year saw a revision from SAAB's Trionic T5.5 to Trionic 7 engine management system. The T7 based engines were the B205L with and the B205R HOT engine with . The first generation 9-3 was also the first Saab available with a diesel engine, a unit also found in the Opel Vectra, Astra G, Signum, Zafira A. Unlike the Saab 900 (NG), the 9-3 is fitted with a CAN bus like the Saab 9-5. A Saab innovation is the
7+3 (chemotherapy) anthracyclines. Addition of glucocorticoids (like prednisolone) or methotrexate or alkylating drugs (like cyclophosphamide or melphalan) to the "7+3" regimen is also of no benefit in AML. The addition of etoposide to the standard "7+3" regimen is "sometimes" of benefit in poor-risk patients (many of which are primary refractory to standard "7+3" induction regimens). It gave rise to the so-called ADE (or DAE = DA + etoposide) induction regimen in AML. The ADE induction (unlike, say, combinations of 7+3 with vinca alkaloids or prednisolone) is still sometimes used, especially in poor-risk AML patients. The addition of 6-thioguanine gave rise to the