Sonic the Hedgehog (character) based on a poorly drawn Sonic, called "Sanic", has been used; typically repeating one of Sonic's catchphrases but with poor grammar. Sega's official Sonic Twitter account has made numerous references to it, and it appeared in official downloadable content for "Sonic Forces" on in-game shirts. Sonic the Hedgehog (character) Sonic the Hedgehog is the title character and protagonist of the "Sonic the Hedgehog" video game series released by Sega, as well as numerous spin-off comics, animations, and other media. Sonic is a blue anthropomorphic hedgehog who can run at supersonic speeds and curl into a ball, primarily to attack enemies.
Sonic hedgehog but low in the developing bronchi. Mice who are deficient in SHH can develop tracheoesophageal fistula (abnormal connection of the esophagus and trachea). Additionally, it a double (SHH-/- ) knockout mouse model exhibited poor lung development. The lungs of the SHH double knockout failed to undergo lobation and branching (the abnormal lungs only developed one branch compared to an extensively branched phenotype of the wildtype). Sonic hedgehog may play a role in mammalian hair cell regeneration. By modulating retinoblastoma protein activity in rat cochlea, sonic hedgehog allows mature hair cells that normally cannot return to a proliferative state to divide