Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Ignatius Valentine Chirol world to places like Morocco, Egypt, South Africa and, especially, India. In addition, he published a number of other books. Chirol died in London in 1929 and was missed by many. Major-General Sir Neill Malcolm called him the "friend of viceroys, the intimate of ambassadors, one might almost say the counsellor of ministers, he was [also] one of the noblest characters that ever adorned British journalism". He was buried in the Brighton Extra Mural Cemetery. Who's Who (UK) Ignatius Valentine Chirol Sir Ignatius Valentine Chirol (28 May 1852 – 22 October 1929) was a British journalist, prolific author, historian and