Edward Jenner full-blown infection. Later, he injected Phipps with variolous material, the routine method of immunization at that time. No disease followed. The boy was later challenged with variolous material and again showed no sign of infection. Donald Hopkins has written, "Jenner's unique contribution was not that he inoculated a few persons with cowpox, but that he then proved [by subsequent challenges] that they were immune to smallpox. Moreover, he demonstrated that the protective cowpox pus could be effectively inoculated from person to person, not just directly from cattle. Jenner successfully tested his hypothesis on 23 additional subjects. Jenner continued his research
Kendall Jenner two signature nail lacquers for the 2011 Nicole by OPI Kardashian Kolors nail polish line, for which the Jenner sisters eventually earned a combined in endorsement profit. On March 16, 2012, the Jenner sisters were named Creative Directors of the "Gillette Venus Gets Ready with Kendall & Kylie Jenner" webisode series, which was originally aired on Gillette's Facebook page. In July 2013, the Jenner sisters formed a partnership with Pascal Mouawad's Glamhouse to create the "Metal Haven by Kendall & Kylie" jewelry collection. In February 2014, the Jenner sisters launched a shoe and handbag line under Steve Madden's "Madden Girl"