Saab 9-5 as undercover, in several parts of its native Sweden, alongside the Volvo V70. Several police forces in the UK also used the 9-5 in their fleets, mostly in Aero specification. The city of Aspen, Colorado, used Saabs as patrol cars from early 1970s until 2005, when the 9-5 was discontinued in favor of Volvo XC90. The town of Vail, Colorado likewise used Saabs from 1980 onwards, but in 2005, the black 9-5 patrol cars were replaced by Ford Explorers, due to budget reasons. In 2006, Lothian and Borders Police in Edinburgh, Scotland, began operating three Saab 9-5 Aero 2.3T patrol
7+3 (chemotherapy) anthracyclines. Addition of glucocorticoids (like prednisolone) or methotrexate or alkylating drugs (like cyclophosphamide or melphalan) to the "7+3" regimen is also of no benefit in AML. The addition of etoposide to the standard "7+3" regimen is "sometimes" of benefit in poor-risk patients (many of which are primary refractory to standard "7+3" induction regimens). It gave rise to the so-called ADE (or DAE = DA + etoposide) induction regimen in AML. The ADE induction (unlike, say, combinations of 7+3 with vinca alkaloids or prednisolone) is still sometimes used, especially in poor-risk AML patients. The addition of 6-thioguanine gave rise to the