Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Valentine Vallis honoured with a footpath plaque in Albert Street, Brisbane, on the Queensland Literary Trail in 1996. Valentine Vallis Valentine Thomas Vallis (1916–2009) was a Queensland poet, lecturer and opera critic. Valentine "Val" Thomas Vallis was born in Gladstone, Queensland on 1 August 1916. His father, Michael was a fisherman and wharf worker. Vallis wrote of his father, mother Daisy and siblings in a number of his poems. After attending Gladstone State School and studying secretarial work at Rockhampton High School (1929-1932), Vallis became a clerk in the Gladstone Town Council. Throughout his childhood he had been an avid reader with