5 to 9 much better than most of this season that [he] felt it deserved mention". Sepinwall praised Edelstein's acting and the episode's "day-in-the-life" format, citing "5 to 9" as proof that "there are still really strong elements to this series." Jonah Krakow of IGN rated "5 to 9" 9.2/10, signifying an "outstanding" episode. Kraków compared it positively to the earlier season six episode "Wilson", which similarly varied from the show's traditional format by depicting events from the perspective of House's friend James Wilson. He deemed the episode "amazing", calling it a "great showcase" for Edelstein and suggesting that a show centered on
7+3 (chemotherapy) anthracyclines. Addition of glucocorticoids (like prednisolone) or methotrexate or alkylating drugs (like cyclophosphamide or melphalan) to the "7+3" regimen is also of no benefit in AML. The addition of etoposide to the standard "7+3" regimen is "sometimes" of benefit in poor-risk patients (many of which are primary refractory to standard "7+3" induction regimens). It gave rise to the so-called ADE (or DAE = DA + etoposide) induction regimen in AML. The ADE induction (unlike, say, combinations of 7+3 with vinca alkaloids or prednisolone) is still sometimes used, especially in poor-risk AML patients. The addition of 6-thioguanine gave rise to the