Santa's Little Helper greyhound's lack of intelligence. In an article that compared "The Simpsons" to the animated series "Family Guy", Todd Camp of the "Fort Worth Star-Telegram" noted that "though Santa's Little Helper may be the only Simpson who's dumber than Homer, the Griffins' pooch <nowiki>[</nowiki>Brian Griffin<nowiki>]</nowiki> is the brainiest member of the household". In 1991, Copley News Service's Alison Ashton described Santa's Little Helper as a "sweet and stupid dog". Tom Coombe of "The Morning Call" wrote in 2002 that "fans of "The Simpsons" will tell you that the cartoon family's dog [...] is often dumb, disobedient and skittish. Fans of the
T helper 3 cell T helper 3 cell T helper 3 cells (T3) are white blood cells of the lymphocyte type. They are involved in regulating the body's immune response. The function of T helper cells generally is to mediate the immune response by secreting cytokines and interacting with B-cells to enhance or inhibit their activity. This is of particular importance in the gut as this is where the highest load of foreign material, food, is present. T3 cells are involved in mucosal immunity and protecting mucosal surfaces in the gut from non-pathogenic non-self antigens. They mediate this non-inflammatory environment by secreting TGF-β and