Cochliobolus lunatus that the underlying disease is controlled, and immune modulators such as granulocyte-macrophage colony-stimulating factor and gamma interferon can be indicated when surgery or antifungals are not feasible alternatives. Allergic fungal manifestations include asthma, rhinitis, sinusitis and bronchopulmonary mycoses caused by a variety of etiological fungal agents including "C. lunatus". These agents provoke humoral immune responses, characterized by type I (immediate) and type III (immune complex mediated) hypersensitivity reactions. Prevalence of these diseases among the atopic population is 20-30 % and 6% in the general population. Allergic rhinitis, more commonly known as hay fever, is less frequently encountered in clinic compared
Double Allergic space. Powderfinger spent less money producing "Double Allergic" than on their previous works. Previously, the band had worked with Tony Cohen, whom Fanning stated was expensive due to his success in the industry. For "Double Allergic" the band chose Tim Whitten, a less well known producer, and because the band knew what they intended to do as they entered the studio they managed to spend less despite the improved sound. Middleton commented on Whitten's capabilities in the recording studio, saying "He's what a band looks for in a producer/engineer, because he's got his own ideas", but stating that Whitten would