Eosinophilic granulomatosis with polyangiitis Eosinophilic granulomatosis with polyangiitis Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg–Strauss syndrome (CSS) or allergic granulomatosis, is an extremely rare autoimmune condition that causes inflammation of small and medium-sized blood vessels (vasculitis) in persons with a history of airway allergic hypersensitivity (atopy). It usually manifests in three stages. The early (prodromal) stage is marked by airway inflammation; almost all patients experience asthma and/or allergic rhinitis. The second stage is characterized by abnormally high numbers of eosinophils (hypereosinophilia), which causes tissue damage, most commonly to the lungs and the digestive tract. The third stage consists of vasculitis, which can
I Should Have Known Better I Should Have Known Better "I Should Have Known Better" is a song by English rock band the Beatles composed by John Lennon (credited to Lennon–McCartney), and originally issued on "A Hard Day's Night", their soundtrack for the film of the same name released on 10 July 1964. "I Should Have Known Better" was also issued as the B-side of the US single "A Hard Day's Night" released on 13 July. An orchestrated version of the song conducted by George Martin appears on the North American version of the album, "A Hard Day's Night Original Motion Picture Soundtrack". In January