Rhinitis goblet cells replace ciliated columnar epithelial cells in the nasal mucous membrane. This results in mucin hypersecretion by goblet cells and decreased mucociliary activity. Nasal secretion are not adequately cleared with clinical manifestation of nasal congestion, sinus pressure, post-nasal dripping, and headache. Over-expression of transient receptor potential (TRP) ion channels, such as TRPA1 and TRPV1, may be involved in the pathogenesis of non-allergic rhinitis. Neurogenic inflammation produced by neuropeptides released from sensory nerve endings to the airways is a proposed common mechanism of association between both allergic and non-allergic rhinitis with asthma. This may explain higher association of rhinitis with
Allergic (album) Allergic (album) Allergic is the third album by Spanish/German rock band Frogcircus. It was released on the German label Soja Music in 2005. The album was recorded in two halves during 2003, the drums and bass tracks at TB Sound Studio in Treuenbrietzen (Germany) by Jürgen Block, and the guitars and vocals at Baraka 3R Studio (Gran Canaria) by Ramón G. Tubío. Additional recordings and mixing took place at Rotor Tonstudio in Berlin with independent engineer Mirsat Neziraj. Singer/guitarist Stone was credited as producer, but appeared under his real name Antonio J. Pérez Alonso. All songs written by Stone. Stone: