Para-equestrian classification 4, 5, 6, 7, 12a/b, 13, 14, 21, 26a, 31a/b and 32 are allowed to have a whip which is held or used by a groom. Grade 1 drivers with Profiles 1, 2, 3, 4, 5, 6, 7, 9, 10a, 12a/b, 13, 14, 26a, 31a/b and 32 are allowed to have a brake operated by a groom. Grade 1 drivers with Profiles 1, 2, 3, 4, 5, 6, 7, 9, 10a, 12a/b, 13, 14, 26a, 31a/b and 32 are allowed to have a strap on feet or foot trough. Grade II is for riders who are higher functioning than Grade
7+3 (chemotherapy) doxorubicin or idarubicin or mitoxantrone). There were attempts to intensify the "7+3" regimen in order to try to improve its efficacy. Attempts were made to prolong the course (cytarabine for 10 days instead of 7, or daunorubicin/idarubicin for 4–5 days instead of 3). On the other hand, there were attempts to minimize the toxicity of the regimen by reducing the dose or the duration of the course. But this proved to compromise the efficacy of the regimen. The addition of vinca alkaloids (vincristine or vinblastine) to the "7+3" regimen, which addition was quite popular in AML in old times (when