Santa's Little Helper him to never wear fur again and instead raise the puppies to be world-class racing dogs. Santa's Little Helper sires another litter of puppies with Dr. Hibbert's poodle in the episode "Today I Am a Clown" (season 15, 2003). These puppies are given away to townspeople. The dog has been neglected or treated unfavorably by the family in some episodes. In "Dog of Death" (season three, 1992), he nearly dies of bloat and they decide to make budget cuts in order to pay for the required operation. Although the dog's life is saved, the family begins to feel the strain
T helper 3 cell T helper 3 cell T helper 3 cells (T3) are white blood cells of the lymphocyte type. They are involved in regulating the body's immune response. The function of T helper cells generally is to mediate the immune response by secreting cytokines and interacting with B-cells to enhance or inhibit their activity. This is of particular importance in the gut as this is where the highest load of foreign material, food, is present. T3 cells are involved in mucosal immunity and protecting mucosal surfaces in the gut from non-pathogenic non-self antigens. They mediate this non-inflammatory environment by secreting TGF-β and