Smallpox 1718. In 1721, Cotton Mather and colleagues provoked controversy in Boston by inoculating hundreds. In 1796, Edward Jenner, a doctor in Berkeley, Gloucestershire, rural England, discovered that immunity to smallpox could be produced by inoculating a person with material from a cowpox lesion. Cowpox is a poxvirus in the same family as variola. Jenner called the material used for inoculation vaccine, from the root word "vacca", which is Latin for cow. The procedure was much safer than variolation, and did not involve a risk of smallpox transmission. Vaccination to prevent smallpox was soon practiced all over the world. During the
Royal Edward (1796 ship) Citations References Royal Edward (1796 ship) Royal Edward was launched in 1782 in France as "Alexandre". The British captured her c.1796, and new owners changed her name. She then sailed for a few years as a West Indiaman before completing four voyages as a slave ship. She returned to the West India trade after leaving the slave trade, and then traded more generally. She was condemned as unseaworthy and broken up in Bengal in 1815. "Royal Edward" was launched in 1782, in France, as "Alexandre". She was reportedly a prize to . "Alexandre" was condemned in Prize Court and sold.