Allergic inflammation Allergic inflammation Allergic inflammation is an important pathophysiological feature of several disabilities or medical conditions including allergic asthma, atopic dermatitis, allergic rhinitis and several ocular allergic diseases. Allergic reactions may generally be divided into two components; the early phase reaction, and the late phase reaction. While the contribution to the development of symptoms from each of the phases varies greatly between diseases, both are usually present and provide us a framework for understanding allergic disease. The early phase of the allergic reaction typically occurs within minutes, or even seconds, following allergen exposure and is also commonly referred to as the
Double Allergic space. Powderfinger spent less money producing "Double Allergic" than on their previous works. Previously, the band had worked with Tony Cohen, whom Fanning stated was expensive due to his success in the industry. For "Double Allergic" the band chose Tim Whitten, a less well known producer, and because the band knew what they intended to do as they entered the studio they managed to spend less despite the improved sound. Middleton commented on Whitten's capabilities in the recording studio, saying "He's what a band looks for in a producer/engineer, because he's got his own ideas", but stating that Whitten would