Santa's Little Helper backyard. In "Bart's Dog Gets an F" (season two, 1991), he manages to infuriate the entire family by destroying valued items in the home. As a result, Homer and Marge want to get rid of the dog, but Bart and Lisa convince them that he can be trained at an obedience school. Santa's Little Helper does not do well there as Bart is unwilling to use a choke chain suggested by the instructor. The night before the final exam, Bart and Santa's Little Helper play, thinking it will be their last few hours together. This bonding breaks down the communication
T helper 3 cell T helper 3 cell T helper 3 cells (T3) are white blood cells of the lymphocyte type. They are involved in regulating the body's immune response. The function of T helper cells generally is to mediate the immune response by secreting cytokines and interacting with B-cells to enhance or inhibit their activity. This is of particular importance in the gut as this is where the highest load of foreign material, food, is present. T3 cells are involved in mucosal immunity and protecting mucosal surfaces in the gut from non-pathogenic non-self antigens. They mediate this non-inflammatory environment by secreting TGF-β and