Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Penicillin (band) its 15th anniversary as a band. On March 9, 2007 Gisho announced that he would leave the band. His last live was his birthday on May 20, 2007 at Shibuya O-East. Since then the band has continued on as a three piece unit. During the February 11, 2008 live, it was announced the Penicillin would once again change labels, this time to Nippon Crown. As of 2010, they are now on That Records, a division of their talent agency Duplex Developments. Penicillin's song "Romance" was covered by And on the compilation "Crush! -90's V-Rock Best Hit Cover Songs-". The album