Chloropyramine Chloropyramine Chloropyramine is a classical ("old", or first-generation) antihistamine drug approved in some Eastern European countries (like Russia) for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Related indications for clinical use include angioedema (Quincke's edema), allergic reactions to insect bites, food and drug allergies, and anaphylactic shock. Chloropyramine is known as a competitive reversible H receptor antagonist (also known as an H inverse agonist), meaning that it exerts its pharmacological action by competing with histamine for the H subtype histamine receptor. By blocking the effects of histamine, the drug inhibits the vasodilation, increased
Allergic response produce histamines. These histamines will act on different areas of the body (eyes, throat, nose, gastrointestinal tract, skin or lungs) to produce symptoms of an allergic reaction. The allergic response is not limited to a certain amount of exposure. If the body is exposed to the allergen multiple times the immune system will react every time the allergen is present. The reason why people get allergies is not known. The allergens are not passed down through generations. It is believed if parents have allergies the child is more likely to be allergic to the same allergens. Some common symptoms include