Allergic inflammation The recruited eosinophils will degranulate releasing a number of cytotoxic molecules (including Major Basic Protein and eosinophil peroxidase) as well as produce a number of cytokines such as IL-5. The recruited T-cells are typically of the Th2 variety and the cytokines they produce lead to further recruitment of mast cells and eosinophils, and in plasma cell isotype switching to IgE which will bind to the mast cell FcεRI receptors and prime the individual for further allergic responses. Allergic inflammation Allergic inflammation is an important pathophysiological feature of several disabilities or medical conditions including allergic asthma, atopic dermatitis, allergic rhinitis and
The Rhinitis Revelation The Rhinitis Revelation "The Rhinitis Revelation" is the sixth episode of the fifth season of the US sitcom "The Big Bang Theory" and the 93rd episode of the show overall. It first aired on CBS on October 20, 2011. Sheldon's mother, Mary Cooper, is going on a Christian cruise called the "Born Again Boat Ride". Before the cruise, she has a weekend in Pasadena and visits Sheldon. However, he is upset when she does not do anything on his itinerary. Instead of his mother cooking chicken and making pecan pie, they go out to a restaurant for sushi; when doing