Smallpox 1718. In 1721, Cotton Mather and colleagues provoked controversy in Boston by inoculating hundreds. In 1796, Edward Jenner, a doctor in Berkeley, Gloucestershire, rural England, discovered that immunity to smallpox could be produced by inoculating a person with material from a cowpox lesion. Cowpox is a poxvirus in the same family as variola. Jenner called the material used for inoculation vaccine, from the root word "vacca", which is Latin for cow. The procedure was much safer than variolation, and did not involve a risk of smallpox transmission. Vaccination to prevent smallpox was soon practiced all over the world. During the
Caitlyn Jenner restrict the legal definition of a person's gender to that assigned at birth. Prior to her public gender transition, Jenner had been married three times, first to Chrystie Scott ( Crownover) from 1972 to 1981. They have two children, son Burton "Burt" Jenner and daughter Cassandra "Casey" Marino ( Jenner). Jenner and Scott's divorce was finalized the first week of January 1981. On January 5, 1981, Jenner married actress Linda Thompson in Hawaii. They have two sons together, Brandon Jenner and Sam Brody Jenner (known as Brody). By February 1986, Jenner and Thompson had separated and subsequently divorced. Their sons