Santa's Little Helper reason he stopped performing as Santa's Little Helper was because "The producers thought... 'Hmmm, Dan barks pretty good, and we are already paying him and he seems to like doing the dog thing... why do we need to pay Welker who comes in here, spends less than an hour, eats all the doughnuts, refuses to come to rehearsals... let's just give the damn dog to Dan!'" Santa's Little Helper has become a well-known dog because of his appearances in the series. A writer for "The Grand Rapids Press" wrote in 2002 that "we all know who Homer, Marge, Bart, Lisa
T helper 3 cell T helper 3 cell T helper 3 cells (T3) are white blood cells of the lymphocyte type. They are involved in regulating the body's immune response. The function of T helper cells generally is to mediate the immune response by secreting cytokines and interacting with B-cells to enhance or inhibit their activity. This is of particular importance in the gut as this is where the highest load of foreign material, food, is present. T3 cells are involved in mucosal immunity and protecting mucosal surfaces in the gut from non-pathogenic non-self antigens. They mediate this non-inflammatory environment by secreting TGF-β and