Santa's Little Helper realistic dilemma faced by many families who own dogs. Other episode ideas come from popular culture. For example, Santa's Little Helper fathering 25 puppies in "Two Dozen and One Greyhounds" is a parody of the Disney film "One Hundred and One Dalmatians", and Mr. Burns' technique of brainwashing him into an attack dog in "Dog of Death" parodies "A Clockwork Orange". Susan McHugh, who teaches theories of animals, literature, and culture at the University of New England, wrote in her 2004 book "Dog" that, "remaining loyal to his unlikely saviours, the boy Bart and his father Homer, this greyhound has
Brother's Little Helper at the time, I didn't think I needed to be taught a lesson while I watched The Simpsons. I still don't." He did, however, "love" the "tag back" to the volunteer fire department seen in the beginning of the episode, and "the fact that they can't find how to fight a satellite fire in their handbook". In his review of "The Simpsons - The Complete Eleventh Season", Brian Tallerico of The Deadbolt considered "Brother's Little Helper" to be one of the season's best episodes. Colin Jacobsson of DVD Movie Guide was favorable as well, calling the episode "pretty good" and