Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Jill Valentine in the first novel, "" (1998), in a series by S. D. Perry. In "Resident Evil: The Umbrella Conspiracy" (1998), Perry's novelisation of the original game, Valentine's Delta Force background is not mentioned, but before her career in law enforcement she is said to have acted as an accomplice for her father, Dick Valentine, who was a professional thief. Several comic books based on the game series have also been released. Toys modeled on Valentine include action figures and figurines. She appears as a character in Bandai's "Resident Evil Deck Building Card Game" (2011). Actors portraying Valentine have appeared at