Chloropyramine Chloropyramine Chloropyramine is a classical ("old", or first-generation) antihistamine drug approved in some Eastern European countries (like Russia) for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Related indications for clinical use include angioedema (Quincke's edema), allergic reactions to insect bites, food and drug allergies, and anaphylactic shock. Chloropyramine is known as a competitive reversible H receptor antagonist (also known as an H inverse agonist), meaning that it exerts its pharmacological action by competing with histamine for the H subtype histamine receptor. By blocking the effects of histamine, the drug inhibits the vasodilation, increased
I Should Have Known Better I Should Have Known Better "I Should Have Known Better" is a song by English rock band the Beatles composed by John Lennon (credited to Lennon–McCartney), and originally issued on "A Hard Day's Night", their soundtrack for the film of the same name released on 10 July 1964. "I Should Have Known Better" was also issued as the B-side of the US single "A Hard Day's Night" released on 13 July. An orchestrated version of the song conducted by George Martin appears on the North American version of the album, "A Hard Day's Night Original Motion Picture Soundtrack". In January