Sonic the Hedgehog (1991 video game) Sonic the Hedgehog (1991 video game) The game's development began in 1990 when Sega ordered its in-house development team to create a game featuring a mascot for the company. After considering a number of suggestions, the developers decided on a blue hedgehog with spikes along his head and spine and named themselves "Sonic Team" to match their character. "Sonic the Hedgehog", designed for fast gameplay, was influenced by the games of "Super Mario" series creator, Shigeru Miyamoto. "Sonic the Hedgehog" uses a novel technique that allows Sonic's sprite to roll along curved scenery, which originated in a tech demo created
Sonic hedgehog are thought to be successively patterned throughout the neural tube by the SHH concentration gradient. Mutual inhibition between pairs of transcription factors expressed in neighboring domains contributes to the development of sharp boundaries, however, in some cases, inhibitory relationship has been found even between pairs of transcription factors from more distant domains. Particularly, NKX2-2 expressed in the V3 domain is reported to inhibit IRX3 expressed in V2 and more dorsal domains, although V3 and V2 are separated by a further domain termed MN. Sonic hedgehog (SHH) is a signaling molecule that is encoded by the same gene sonic hedgehog. SHH