Santa's Little Helper and is the center of the plots of several episodes. During the course of the show, he has fathered litters of puppies, passed obedience school, had surgery for bloat, replaced Duffman as the mascot for Duff Beer, and been trained as a police dog at Springfield's Animal Police Academy. Some of the episodes that focus on Santa's Little Helper have been inspired by popular culture or real experiences that staff members of the show have gone through. Although cartoon animals are often anthropomorphized, Santa's Little Helper generally exhibits canine behavior. Cast member Dan Castellaneta currently provides the dog's sounds on
Brother's Little Helper medication. The episode features former Major League Baseball player Mark McGwire as himself. Finishing in 51st place, ratings for "Brother's Little Helper" were considered disappointing by "Deseret News", although the episode became the most watched program on the network that night. Following its broadcast, the episode was positively received by critics. In response to the episode, five months after the episode originally aired, United States president Bill Clinton held the first ever White House conference on Mental Health. Principal Skinner holds a Fire Prevention site at the Springfield Elementary Schoolyard. Then a skit featuring Ned and Maude Flanders goes awry.