Edward Jenner full-blown infection. Later, he injected Phipps with variolous material, the routine method of immunization at that time. No disease followed. The boy was later challenged with variolous material and again showed no sign of infection. Donald Hopkins has written, "Jenner's unique contribution was not that he inoculated a few persons with cowpox, but that he then proved [by subsequent challenges] that they were immune to smallpox. Moreover, he demonstrated that the protective cowpox pus could be effectively inoculated from person to person, not just directly from cattle. Jenner successfully tested his hypothesis on 23 additional subjects. Jenner continued his research
Sir William Jenner, 1st Baronet Sir William Jenner, 1st Baronet Sir William Jenner, 1st Baronet, GCB, QHP, FRCP, FRS (30 January 1815 – 11 December 1898) was a significant English physician primarily known for having discovered the distinction between typhus and typhoid. Jenner was born at Chatham on 30 January 1815, and educated at University College London. He became a Member of the Royal College of Surgeons of England (M.R.C.S.) in 1837, a Fellow of the Royal College of Physicians (F.R.C.P.) in 1852, and in 1844 took the London M.D. In 1847 he began at the London Fever Hospital investigations into cases of continued fever