Rhinitis goblet cells replace ciliated columnar epithelial cells in the nasal mucous membrane. This results in mucin hypersecretion by goblet cells and decreased mucociliary activity. Nasal secretion are not adequately cleared with clinical manifestation of nasal congestion, sinus pressure, post-nasal dripping, and headache. Over-expression of transient receptor potential (TRP) ion channels, such as TRPA1 and TRPV1, may be involved in the pathogenesis of non-allergic rhinitis. Neurogenic inflammation produced by neuropeptides released from sensory nerve endings to the airways is a proposed common mechanism of association between both allergic and non-allergic rhinitis with asthma. This may explain higher association of rhinitis with
Just Dropped In (To See What Condition My Condition Was In) Just Dropped In (To See What Condition My Condition Was In) "Just Dropped In (To See What Condition My Condition Was In)" is a counterculture era song written by Mickey Newbury and, in 1968, a chart hit for Kenny Rogers and the First Edition. Said to reflect the glue sniffing experience, the song was intended to be a warning about the dangers of using the drug. First recorded on October 10, 1967, by Teddy Hill & the Southern Soul as a single on Rice Records (Rice 5028 b/w "Stagger Lee") and produced by Norro Wilson, Jerry Lee Lewis covered the