5 to 9 the episode's central character, "In "5 to 9," we get more face time with Cuddy, and she's less of a cypher than usual, but her true nature remains tantalizingly out of reach." Handlen commented that the episode had some good scenes, but ultimately did little to advance the show, grading it "B". TV Squad's Jonathan Toomey raised similar issues, noting that "'5 to 9' wasn't a bad episode (in many ways, it felt like a back-door pilot for Cuddy), but it was, in a word, pointless." Toomey wrote that "At the end of the day, '5 to 9' doesn't really
7+3 (chemotherapy) anthracyclines. Addition of glucocorticoids (like prednisolone) or methotrexate or alkylating drugs (like cyclophosphamide or melphalan) to the "7+3" regimen is also of no benefit in AML. The addition of etoposide to the standard "7+3" regimen is "sometimes" of benefit in poor-risk patients (many of which are primary refractory to standard "7+3" induction regimens). It gave rise to the so-called ADE (or DAE = DA + etoposide) induction regimen in AML. The ADE induction (unlike, say, combinations of 7+3 with vinca alkaloids or prednisolone) is still sometimes used, especially in poor-risk AML patients. The addition of 6-thioguanine gave rise to the