Edward Jenner full-blown infection. Later, he injected Phipps with variolous material, the routine method of immunization at that time. No disease followed. The boy was later challenged with variolous material and again showed no sign of infection. Donald Hopkins has written, "Jenner's unique contribution was not that he inoculated a few persons with cowpox, but that he then proved [by subsequent challenges] that they were immune to smallpox. Moreover, he demonstrated that the protective cowpox pus could be effectively inoculated from person to person, not just directly from cattle. Jenner successfully tested his hypothesis on 23 additional subjects. Jenner continued his research
Royal Edward (1796 ship) then renamed her. Though volumes of "Lloyd's Register" and the "Register of Shipping" give a capture year of 1796, she does not enter "Lloyd's Register" before 1798. She sailed as a West Indiaman before entering into the slave trade. First slave voyage (1799-1800): Captain Thomas Bushell sailed from England on 4 September 1799. She gathered her slaves at Bonny Island, and arrived at Kingston, Jamaica on 14 July 1800. She had embarked 432 slaves and she disembarked 316, for a loss rate of 8.3%. "Royal Edward" left Jamaica on 18 October and arrived back at Liverpool on 23 December. She