Chloropyramine Chloropyramine Chloropyramine is a classical ("old", or first-generation) antihistamine drug approved in some Eastern European countries (like Russia) for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Related indications for clinical use include angioedema (Quincke's edema), allergic reactions to insect bites, food and drug allergies, and anaphylactic shock. Chloropyramine is known as a competitive reversible H receptor antagonist (also known as an H inverse agonist), meaning that it exerts its pharmacological action by competing with histamine for the H subtype histamine receptor. By blocking the effects of histamine, the drug inhibits the vasodilation, increased
U Should've Known Better U Should've Known Better "U Should've Known Better" is a song by American recording artist Monica. It was written in collaboration with Harold Lilly and Jermaine Dupri, and produced by the latter along with frequent co-producer Bryan Michael Cox for her original third studio album, "All Eyez on Me" (2002). When the album was shelved for release outside Japan, the song was one out of five original records that were transferred into its new version, "After the Storm" (2003). A contemporary R&B slow jam, "U Should've Known Better" contains elements of soul music and rock music. Built on an pulsating