Immunogenetics Immunogenetics Immunogenetics or immungenetics is the branch of medical genetics that explores the relationship between the immune system and genetics. Autoimmune diseases, such as type 1 diabetes, are complex genetic traits which result from defects in the immune system. Identification of genes defining the immune defects may identify new target genes for therapeutic approaches. Alternatively, genetic variations can also help to define the immunological pathway leading to disease. Its origin is usually attributed to Edward Jenner, who discovered in 1796 that cowpox, or vaccinia, induced protection against human smallpox. It took two centuries before the World Health Organization announced in
Edward Jenner experience needed to become a surgeon himself. In 1770, Jenner became apprenticed in surgery and anatomy under surgeon John Hunter and others at St George's Hospital. William Osler records that Hunter gave Jenner William Harvey's advice, well-known in medical circles (and characteristic of the Age of Enlightenment), "Don't think; try." Hunter remained in correspondence with Jenner over natural history and proposed him for the Royal Society. Returning to his native countryside by 1773, Jenner became a successful family doctor and surgeon, practising on dedicated premises at Berkeley. Jenner and others formed the Fleece Medical Society or Gloucestershire Medical Society, so