Charles Harrison Blackley Charles Harrison Blackley Charles Harrison Blackley (5 April 1820 – 4 September 1900) was the discoverer of the mechanism behind allergic rhinitis caused by pollen, commonly called hay fever. The isolation of hay fever as a condition had been known since 1819 through the work of John Bostock. Blackley was the first to connect pollen to the condition, and though he held some later discredited views, his insight was an important step in the research of allergens. His most important work was a book titled the "Experimental Researches on the Causes and Nature of Catarrhus aestivus", published in 1873. Charles
Allergic bronchopulmonary aspergillosis placing global burden at around 4.8 million people affected. The Eastern Mediterranean region had the lowest estimated prevalence, with a predicted case burden of 351,000; collectively, the Americas had the highest predicted burden at 1,461,000 cases. These are likely underestimates of total prevalence, given the exclusion of CF patients and children from the study, as well as diagnostic testing being limited in less developed regions. Allergic bronchopulmonary aspergillosis Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterised by an exaggerated response of the immune system (a hypersensitivity response) to the fungus "Aspergillus" (most commonly "Aspergillus fumigatus"). It occurs most often in