Ze339 Ze339 Ze339 brand herbal extracts are taken from the leaves of a unique variety (Petzell) of the butterbur ("Petasites hybridus") plant. Petzell is grown on GAP-managed farms in Europe. In Switzerland, South Korea and Brazil, tablets containing Ze339 brand herbal extracts are marketed under the brand name Tesalin. Ze339 is marketed in the US as Zarbee's Naturals Seasonal Relief. Ze339 is indicated for seasonal allergic rhinitis (hay fever). The ingredient has been evaluated in placebo-controlled, double-blind clinical studies. Ze339 was shown to be as effective as the antihistamines cetirizine and fexofenadine. Against desloratadine, an improved version of loratadine, Ze339 had
Aspirin exacerbated respiratory disease Aspirin exacerbated respiratory disease Aspirin exacerbated respiratory disease (AERD), also termed aspirin-induced asthma, is a medical condition initially defined as consisting of three key features: asthma, respiratory symptoms exacerbated by aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), and nasal polyps. The symptoms of respiratory reactions in this syndrome are hypersensitivity reactions to NSAIDs rather than the typically described true allergic reactions that trigger other common allergen-induced asthma, rhinitis, or hives. The NSAID-induced reactions do not appear to involve the common mediators of true allergic reactions, immunoglobulin E or T cells. Rather, AERD is a type of NSAID-induced hypersensitivity syndrome. EAACI/WHO