Cochliobolus lunatus that the underlying disease is controlled, and immune modulators such as granulocyte-macrophage colony-stimulating factor and gamma interferon can be indicated when surgery or antifungals are not feasible alternatives. Allergic fungal manifestations include asthma, rhinitis, sinusitis and bronchopulmonary mycoses caused by a variety of etiological fungal agents including "C. lunatus". These agents provoke humoral immune responses, characterized by type I (immediate) and type III (immune complex mediated) hypersensitivity reactions. Prevalence of these diseases among the atopic population is 20-30 % and 6% in the general population. Allergic rhinitis, more commonly known as hay fever, is less frequently encountered in clinic compared
Worse is better Rise of Worse is Better", Gabriel claimed that "Worse-is-Better" is a model of software design and implementation which has the following characteristics (in approximately descending order of importance): Gabriel argued that early Unix and C, developed by Bell Labs, are examples of this design approach. Gabriel contrasted his philosophy with what he called the "MIT/Stanford style of design" or "MIT approach" (also known as "the Right Thing"), which he described as follows. Contrasts are in bold: Gabriel argued that "Worse is better" produced more "successful" software than the MIT approach: As long as the initial program is basically good, it