Eosinophilic granulomatosis with polyangiitis Eosinophilic granulomatosis with polyangiitis Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg–Strauss syndrome (CSS) or allergic granulomatosis, is an extremely rare autoimmune condition that causes inflammation of small and medium-sized blood vessels (vasculitis) in persons with a history of airway allergic hypersensitivity (atopy). It usually manifests in three stages. The early (prodromal) stage is marked by airway inflammation; almost all patients experience asthma and/or allergic rhinitis. The second stage is characterized by abnormally high numbers of eosinophils (hypereosinophilia), which causes tissue damage, most commonly to the lungs and the digestive tract. The third stage consists of vasculitis, which can
The Rhinitis Revelation The Rhinitis Revelation "The Rhinitis Revelation" is the sixth episode of the fifth season of the US sitcom "The Big Bang Theory" and the 93rd episode of the show overall. It first aired on CBS on October 20, 2011. Sheldon's mother, Mary Cooper, is going on a Christian cruise called the "Born Again Boat Ride". Before the cruise, she has a weekend in Pasadena and visits Sheldon. However, he is upset when she does not do anything on his itinerary. Instead of his mother cooking chicken and making pecan pie, they go out to a restaurant for sushi; when doing