Self-contained breathing apparatus pressure changes with ambient temperature. As temperature decreases, the pressure inside the cylinder decreases. The relationship between the temperature and the pressure of a gas is defined by the formula "PV" = "nRT". (See Universal gas constant.) What is particularly important to understand from the formula is that the temperature is in kelvins, not degrees Fahrenheit. Consider the freezing point of water at 32 °F (0 °C, 273.15 K) and compare it to 96 °F (35.6 °C or 308.71 K; normal human body temperature is 37 °C). While 96 is arithmetically three times 32, the difference in temperature from a
Human body temperature raised, the result is a fever. Most fevers are caused by infectious disease and can be lowered, if desired, with antipyretic medications. An early morning temperature higher than or a late afternoon temperature higher than is normally considered a fever, assuming that the temperature is elevated due to a change in the hypothalamus's setpoint. Lower thresholds are sometimes appropriate for elderly people. The normal daily temperature variation is typically , but can be greater among people recovering from a fever. An organism at optimum temperature is considered "afebrile" or "apyrexic", meaning "without fever". If temperature is raised, but the setpoint