Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
James Valentine (musician) James Valentine (musician) James Burgon Valentine (born October 5, 1978) is an American musician and songwriter. He is the lead guitarist for the pop rock band Maroon 5. Valentine was born in Lincoln, Nebraska. He was raised as a member of The Church of Jesus Christ of Latter-day Saints (Mormon) and has three sisters and one brother. His mother is a former beauty queen, who was a school teacher before becoming a stay-at-home mom to raise her five children. His younger sister, Amanda Valentine has been a contestant on "Project Runway" two times starring in Season 11 and Season 13,