HEK 293 cells cell, all of which are abundant in kidneys. However, the original adenovirus transformation was inefficient, suggesting that the cell that finally produced the HEK 293 line may have been unusual in some fashion. Graham and coworkers provided evidence that HEK 293 cells and other human cell lines generated by adenovirus transformation of human embryonic kidney cells have many properties of immature neurons, suggesting that the adenovirus preferentially transformed a neuronal lineage cell in the original kidney culture. A comprehensive study of the genomes and transcriptomes of HEK 293 and five derivative cell lines compared the HEK 293 transcriptome with that
How to Make a Spaceship the one headed by Paul Allen and Burt Rutan, of SpaceShipOne. The book ends with an epilogue about Richard Branson's Virgin Galactic scooping up the SpaceShipOne technology, and the spaceplane itself ending up in the Smithsonian National Air and Space Museum. The book includes a preface by Richard Branson, and an afterword by Stephen Hawking. The book was originally entitled ""Beyond: Peter Diamandis and the Adventure of Space"", when it was sold preemptively to Penguin Books in 2014. "How to Make a Spaceship" was released in September 2016, in trade paperback, hardcover, audio book and e-book formats. The work was