Edward Jenner humans a cowpox vaccine against smallpox. For example, Dorset farmer Benjamin Jesty successfully vaccinated and presumably induced immunity with cowpox in his wife and two children during a smallpox epidemic in 1774, but it was not until Jenner's work that the procedure became widely understood. Jenner may have been aware of Jesty's procedures and success. A similar observation had also been made in France by Jacques Antoine Rabaut-Pommier in 1780. Noting the common observation that milkmaids were generally immune to smallpox, Jenner postulated that the pus in the blisters that milkmaids received from cowpox (a disease similar to smallpox, but
Frank Jenner into his home for tea and told him about the gospel. Jenner converted to Christianity and, when he went home, told Jessie that she was a sinner bound for hell and therefore in need of salvation. According to Wilson's biography of Jenner, Jessie thought that Jenner had become manic or insane. They had a young daughter named Ann by this point and Jenner was gambling so much that he was not providing for his family. For both of these reasons, Jessie left Jenner and moved to Corowa to work on a farm, taking Ann with her. She said that she