Sonic the Hedgehog (character) based on a poorly drawn Sonic, called "Sanic", has been used; typically repeating one of Sonic's catchphrases but with poor grammar. Sega's official Sonic Twitter account has made numerous references to it, and it appeared in official downloadable content for "Sonic Forces" on in-game shirts. Sonic the Hedgehog (character) Sonic the Hedgehog is the title character and protagonist of the "Sonic the Hedgehog" video game series released by Sega, as well as numerous spin-off comics, animations, and other media. Sonic is a blue anthropomorphic hedgehog who can run at supersonic speeds and curl into a ball, primarily to attack enemies.
Sonic hedgehog of prostate cancer tumours. For SHH to be expressed in the developing embryo limbs, a morphogen called fibroblast growth factors must be secreted from the apical ectodermal ridge. Sonic hedgehog has also been shown to act as an axonal guidance cue. It has been demonstrated that SHH attracts commissural axons at the ventral midline of the developing spinal cord. Specifically, SHH attracts retinal ganglion cell (RGC) axons at low concentrations and repels them at higher concentrations. The absence (non-expression) of SHH has been shown to control the growth of nascent hind limbs in cetaceans (whales and dolphins). The sonic hedgehog