History of penicillin History of penicillin The history of penicillin follows a number of observations and discoveries of apparent evidence of antibiotic activity in molds before the modern isolation of the chemical penicillin in 1928. There are anecdotes about ancient societies using molds to treat infections, and in the following centuries many people observed the inhibition of bacterial growth by various molds. However, it is unknown if the species involved were "Penicillium" species or if the antimicrobial substances produced were penicillin. The Scottish physician Alexander Fleming was the first to suggest that a "Penicillium" mold must secrete an antibacterial substance, and the first
A. S. Valentine of the game after coming to the aid of James Van Cleve during a fight against Pittsburgh's Joe Trees. After several appeals, Valentine left the field reportedly "crying like a baby" by the local media. In 1895, Allegheny declined to field a team after learning of an investigation into the club by the Amateur Athletic Union, over reports that the team had been secretly paying players. As a result, Valentine became a referee. He officiated a game that year between the Duquesne Country and Athletic Club and Greensburg. The game was filled with fights and arguments. Valentine refused to return