Santa's Little Helper of whom, admittedly, have strong speech impediments, he doesn’t talk or wisecrack or engage in shenanigans. His abilities and powers begin and end with masticating, defecating, and regular napping. You know, just like a real dog. Consequently, episodes devoted to Santa’s Little Helper tend to be a little on the sleepy side, even the "Simpsons" Christmas special that launched the series." Since his first appearance on "The Simpsons", Santa's Little Helper has appeared in merchandise relating to the show. On the board art of "The Simpsons Clue", a 2000 board game by USAopoly based on "Clue", he is shown drinking
T helper 3 cell T helper 3 cell T helper 3 cells (T3) are white blood cells of the lymphocyte type. They are involved in regulating the body's immune response. The function of T helper cells generally is to mediate the immune response by secreting cytokines and interacting with B-cells to enhance or inhibit their activity. This is of particular importance in the gut as this is where the highest load of foreign material, food, is present. T3 cells are involved in mucosal immunity and protecting mucosal surfaces in the gut from non-pathogenic non-self antigens. They mediate this non-inflammatory environment by secreting TGF-β and