Penicillin nontoxic in humans by first performing toxicity tests in animals and then on humans. His subsequent experiments on penicillin's response to heat and pH allowed Fleming to increase the stability of the compound. The one test that modern scientists would find missing from his work was the test of penicillin on an infected animal, the results of which would likely have sparked great interest in penicillin and sped its development by almost a decade. The importance of his work has been recognized by the placement of an International Historic Chemical Landmark at the Alexander Fleming Laboratory Museum in London on
Perfect Day (1929 film) sound effects to punctuate a visual gag — a technique The Three Stooges would build their entire film career around — was still in its infancy in 1929. The loud, ringing CLANG heard when Stan is beaned on the head with the Model T's clutch would be termed by a 1929 film reviewer as "the funniest effect so far heard in a comedy." The second half of the Stooges' 1948 film "Pardon My Clutch" and its remake, "Wham Bam Slam", is a remake of "Perfect Day". Chapters — called Tents — of The Sons of the Desert, the international Laurel