Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Rhoda Valentine Lewis Rhoda Valentine Lewis Rhoda Valentine Lewis (August 31, 1906September 12, 1991) was the first female justice on the Supreme Court of Hawaii. Lewis was born in Chicago on August 31, 1906, to parents Charles Tobias and Josephine Lewis. She moved to Honolulu and attended the Punahou School; then moved to Manila, and attended the American-European School; and graduated from the Frances Willard Jr. High School in Berkeley, California. She graduated from Stanford University in 1927, and received her Juris Doctor from Stanford Law School in 1929, graduating first in her class, and becoming a member of the Order of the