Sonic the Hedgehog (1991 video game) 1 Boomed", a ROM hack which implements Sonic's redesign from the "Sonic Boom" animated series. Sonic the Hedgehog (1991 video game) The game's development began in 1990 when Sega ordered its in-house development team to create a game featuring a mascot for the company. After considering a number of suggestions, the developers decided on a blue hedgehog with spikes along his head and spine and named themselves "Sonic Team" to match their character. "Sonic the Hedgehog", designed for fast gameplay, was influenced by the games of "Super Mario" series creator, Shigeru Miyamoto. "Sonic the Hedgehog" uses a novel technique that
Sonic hedgehog including the limb and midline structures in the brain, spinal cord, the thalamus by the "zona limitans intrathalamica" the lungs, and the teeth. Mutations in the human sonic hedgehog gene, "SHH", cause holoprosencephaly type 3 HPE3 as a result of the loss of the ventral midline. Sonic hedgehog is secreted at the zone of polarizing activity, which is located on the posterior side of a limb bud in an embryo. The sonic hedgehog transcription pathway has also been linked to the formation of specific kinds of cancerous tumors, including the embryonic cerebellar tumor, and medulloblastoma, as well as the progression