Jenner Township, Somerset County, Pennsylvania named in honor of Dr. Edward Jenner, discoverer of the smallpox vaccine. Early Jenner Township settlers were primarily German and English speakers engaged in agriculture. Pennsylvania Dutch was still spoken in rural parts of the township until the 1960s. Jenner Crossroads, the township's first substantial European settlement, grew near a grist mill and tavern stop established about 1800 along the Pennsylvania Road. Samuel Steel built a sawmill at Jenner Crossroads in 1817; John Shopwood opened a hotel in 1825, and Samuel Elder opened the first store in 1836 Other early industry in the township included a sawmill on Quemahoning Creek
Edward Jenner called because it met in the parlour of the Fleece Inn, Rodborough (in Gloucestershire). Members dined together and read papers on medical subjects. Jenner contributed papers on angina pectoris, ophthalmia, and cardiac valvular disease and commented on cowpox. He also belonged to a similar society which met in Alveston, near Bristol. He became a master mason on 30 December 1802, in Lodge of Faith and Friendship #449. From 1812–1813, he served as worshipful master of Royal Berkeley Lodge of Faith and Friendship. Edward Jenner was elected fellow of the Royal Society in 1788, following his publication of a careful study