Smallpox 1718. In 1721, Cotton Mather and colleagues provoked controversy in Boston by inoculating hundreds. In 1796, Edward Jenner, a doctor in Berkeley, Gloucestershire, rural England, discovered that immunity to smallpox could be produced by inoculating a person with material from a cowpox lesion. Cowpox is a poxvirus in the same family as variola. Jenner called the material used for inoculation vaccine, from the root word "vacca", which is Latin for cow. The procedure was much safer than variolation, and did not involve a risk of smallpox transmission. Vaccination to prevent smallpox was soon practiced all over the world. During the
Kris Jenner Jenner Communications, which is based in Los Angeles. Since before the start of "Keeping Up with the Kardashians", she has managed her daughter Kim's career. She also is involved with the business management of her other daughters and son. Jenner opened a children's boutique in 2004 with her eldest daughter, Kourtney. The boutique was called "Smooch" and was open for almost six years before closing down in 2009. Jenner's autobiography, "Kris Jenner... and All Things Kardashian", was released in November 2011. She later wrote a cookbook entitled "In the Kitchen with Kris: A Kollection of Kardashian-Jenner Family Favorites", which was