Rhinitis inhibit cyclooxygenase 1 (COX1), can worsen rhinitis and asthma symptoms in individuals with a history of either one of these diseases. These exacerbations most often appear due to NSAID hypersensitivity reactions rather than NSAID-induced allergic reactions. The antihistamine azelastine, applied as a nasal spray, may be effective for vasomotor rhinitis. Fluticasone propionate or budesonide (both are steroids) in nostril spray form may also be used for symptomatic treatment. The antihistamine cyproheptadine is also effective, probably due to its antiserotonergic effects. A systematic review on non-allergic rhinitis reports improvement of overall function after treatment with capsaicin (the active component of chili
I Should Have Known Better I Should Have Known Better "I Should Have Known Better" is a song by English rock band the Beatles composed by John Lennon (credited to Lennon–McCartney), and originally issued on "A Hard Day's Night", their soundtrack for the film of the same name released on 10 July 1964. "I Should Have Known Better" was also issued as the B-side of the US single "A Hard Day's Night" released on 13 July. An orchestrated version of the song conducted by George Martin appears on the North American version of the album, "A Hard Day's Night Original Motion Picture Soundtrack". In January