Old Yeller-Belly interview footage of Homer disowning Santa's Little Helper. He becomes Suds' new owner and takes the family's fortunes to himself, much to the Simpsons' discomfort, and Homer is wracked with complete remorse for saying such a horrible thing on TV. Figuring that if they can get Duffman to replace Suds as the Duff mascot, they can get their dog back, the Simpsons seek Duffman, who has become an ordinary man named Barry Duffman who helps the less fortunate (by teaching math at a local halfway house). The Simpsons ask him to help the family get Santa's Little Helper back at
T helper cell because such knowledge may be very useful in the treatment of disease and in increasing the effectiveness of vaccination. Proliferating helper T cells that develop into effector T cells differentiate into two major subtypes of cells known as T1 and T2 cells (also known as Type 1 and Type 2 helper T cells, respectively). T1 helper cells lead to an increased cell-mediated response, typically against intracellular bacteria and protozoa. They are triggered by IL-12 and their effector cytokines are IFN-γ and IL-2. The main effector cells of T1 immunity are macrophages as well as CD8 T cells, IgG B cells,