Santa's Little Helper realistic dilemma faced by many families who own dogs. Other episode ideas come from popular culture. For example, Santa's Little Helper fathering 25 puppies in "Two Dozen and One Greyhounds" is a parody of the Disney film "One Hundred and One Dalmatians", and Mr. Burns' technique of brainwashing him into an attack dog in "Dog of Death" parodies "A Clockwork Orange". Susan McHugh, who teaches theories of animals, literature, and culture at the University of New England, wrote in her 2004 book "Dog" that, "remaining loyal to his unlikely saviours, the boy Bart and his father Homer, this greyhound has
Brother's Little Helper medication. The episode features former Major League Baseball player Mark McGwire as himself. Finishing in 51st place, ratings for "Brother's Little Helper" were considered disappointing by "Deseret News", although the episode became the most watched program on the network that night. Following its broadcast, the episode was positively received by critics. In response to the episode, five months after the episode originally aired, United States president Bill Clinton held the first ever White House conference on Mental Health. Principal Skinner holds a Fire Prevention site at the Springfield Elementary Schoolyard. Then a skit featuring Ned and Maude Flanders goes awry.