History of penicillin History of penicillin The history of penicillin follows a number of observations and discoveries of apparent evidence of antibiotic activity in molds before the modern isolation of the chemical penicillin in 1928. There are anecdotes about ancient societies using molds to treat infections, and in the following centuries many people observed the inhibition of bacterial growth by various molds. However, it is unknown if the species involved were "Penicillium" species or if the antimicrobial substances produced were penicillin. The Scottish physician Alexander Fleming was the first to suggest that a "Penicillium" mold must secrete an antibacterial substance, and the first
A. S. Valentine in a game for Shadyside Academy as that team was defeated by the Pittsburgh A.C., 26–0. That same year, he scored a touchdown against the Greensburg Athletic Association, during a 10–5 Allegheny win. During a game against the Detroit Athletic Association on November 11, 1893, Valentine reportedly openly punched Detroit's quarterback so openly. The officials ignored the incident, and the Detroiter used the next play to retaliate against Valentine. Shortly after, a brawl between the two clubs erupted. Allegheny would go on to win the game 18–0. In 1894, during a game against the Pittsburgh A.C., Valentine was thrown out