Simpsons Roasting on an Open Fire to waste money on getting his son Bart's tattoo removed. He decides to keep their financial troubles a secret and gets a job as a shopping mall Santa Claus, but later discovers that the job does not pay enough. Desperate for a miracle, Homer and Bart go to the dog-racing track on Christmas Eve in hopes of earning some money but end up adopting an abandoned greyhound, Santa's Little Helper. The episode was written by Mimi Pond, and it was directed by David Silverman. "Simpsons Roasting on an Open Fire" was nominated for two Emmy Awards in 1990, and has
T helper 3 cell T helper 3 cell T helper 3 cells (T3) are white blood cells of the lymphocyte type. They are involved in regulating the body's immune response. The function of T helper cells generally is to mediate the immune response by secreting cytokines and interacting with B-cells to enhance or inhibit their activity. This is of particular importance in the gut as this is where the highest load of foreign material, food, is present. T3 cells are involved in mucosal immunity and protecting mucosal surfaces in the gut from non-pathogenic non-self antigens. They mediate this non-inflammatory environment by secreting TGF-β and