9 (2009 animated film) declares 2 as dead, but 9, having seen the condemned factory where the Cat-Beast took him, decides to rescue him. 9 and 5 venture to the factory where they find 2. The Cat-Beast attacks the trio, but are saved by the warrior 7 (Jennifer Connelly). 9, drawn by curiosity, connects the talisman to the derelict Fabrication Machine, reviving it, and it subsequently kills 2 by sucking out his soul. 9, 5, and 7 manage to escape the factory. 7 takes 9 and 5 to an abandoned library, where the mute scholar twins, 3 and 4, show 9 a film showing
7+3 (chemotherapy) anthracyclines. Addition of glucocorticoids (like prednisolone) or methotrexate or alkylating drugs (like cyclophosphamide or melphalan) to the "7+3" regimen is also of no benefit in AML. The addition of etoposide to the standard "7+3" regimen is "sometimes" of benefit in poor-risk patients (many of which are primary refractory to standard "7+3" induction regimens). It gave rise to the so-called ADE (or DAE = DA + etoposide) induction regimen in AML. The ADE induction (unlike, say, combinations of 7+3 with vinca alkaloids or prednisolone) is still sometimes used, especially in poor-risk AML patients. The addition of 6-thioguanine gave rise to the