Edward Jenner full-blown infection. Later, he injected Phipps with variolous material, the routine method of immunization at that time. No disease followed. The boy was later challenged with variolous material and again showed no sign of infection. Donald Hopkins has written, "Jenner's unique contribution was not that he inoculated a few persons with cowpox, but that he then proved [by subsequent challenges] that they were immune to smallpox. Moreover, he demonstrated that the protective cowpox pus could be effectively inoculated from person to person, not just directly from cattle. Jenner successfully tested his hypothesis on 23 additional subjects. Jenner continued his research
Edward Jenner of nestling birds in general." Jenner's nephew assisted in the study. He was born on 30 June 1737. Jenner's understanding of the cuckoo's behaviour was not entirely believed until the artist Jemima Blackburn, a keen observer of bird life, saw a blind nestling pushing out a host's egg. Her description and illustration of this were enough to convince Charles Darwin to revise a later edition of "On the Origin of Species". Jenner married Catherine Kingscote (died 1815 from tuberculosis) in March 1788. He might have met her while he and other fellows were experimenting with balloons. Jenner's trial balloon descended