Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
William Valentine Doctorate in Pedagogy from the Central Philippine University in Iloilo City. The university honored him further on October 1, 2005, when Central Philippine University celebrated its Founder's Day with the unveiling of a bronze bust of Valentine at Old Valentine Hall. In Negros, the Bacolod Evangelical Church and the Bacolod Christian College as well as schools and missions throughout the province are outgrowths of Valentine’s work. William Valentine "For the Nova Scotian painter see William Valentine (painter)" William Orison Valentine (May 9, 1862– February 2, 1928) was an innovative educator and missionary in service of the American Baptist Foreign Mission