Edward Jenner full-blown infection. Later, he injected Phipps with variolous material, the routine method of immunization at that time. No disease followed. The boy was later challenged with variolous material and again showed no sign of infection. Donald Hopkins has written, "Jenner's unique contribution was not that he inoculated a few persons with cowpox, but that he then proved [by subsequent challenges] that they were immune to smallpox. Moreover, he demonstrated that the protective cowpox pus could be effectively inoculated from person to person, not just directly from cattle. Jenner successfully tested his hypothesis on 23 additional subjects. Jenner continued his research
Royal Edward (1796 ship) Royal Edward (1796 ship) Royal Edward was launched in 1782 in France as "Alexandre". The British captured her c.1796, and new owners changed her name. She then sailed for a few years as a West Indiaman before completing four voyages as a slave ship. She returned to the West India trade after leaving the slave trade, and then traded more generally. She was condemned as unseaworthy and broken up in Bengal in 1815. "Royal Edward" was launched in 1782, in France, as "Alexandre". She was reportedly a prize to . "Alexandre" was condemned in Prize Court and sold. New owners