Santa's Little Helper prompted satires of contemporary dog culture, from Barbara Woodhouse's authoritarian training methods [in "Bart's Dog Gets an F"] to Lassie's flawless service to the status quo [in "The Canine Mutiny"]." Although cast member Dan Castellaneta occasionally voiced Santa's Little Helper for bit parts, American voice artist Frank Welker most often provided the sounds of the dog and other animals on the show from "Bart's Dog Gets an F", which aired on March 7, 1991, to "Home Sweet Homediddly-Dum-Doodily", which aired on October 1, 1995. He said on his official website in 2007 that he liked portraying Santa's Little Helper because
Brother's Little Helper medication. The episode features former Major League Baseball player Mark McGwire as himself. Finishing in 51st place, ratings for "Brother's Little Helper" were considered disappointing by "Deseret News", although the episode became the most watched program on the network that night. Following its broadcast, the episode was positively received by critics. In response to the episode, five months after the episode originally aired, United States president Bill Clinton held the first ever White House conference on Mental Health. Principal Skinner holds a Fire Prevention site at the Springfield Elementary Schoolyard. Then a skit featuring Ned and Maude Flanders goes awry.