Phlorizin Phlorizin Phlorizin (also referred to as phloridzin; chemical name phloretin-2'-β--glucopyranoside) is a glucoside of phloretin, a dihydrochalcone, a family of bicyclic flavonoids, which in turn is a subgroup in the diverse phenylpropanoid synthesis pathway in plants. Phlorizin is found primarily in unripe "Malus" (apple), root bark of apple, trace amounts have been found in strawberry. In "Malus", it is most abundant in vegetative tissues (such as leaves and bark) and seeds. Closely related species, such as pear ("Pyrus communis"), cherry, and other fruit trees in the "Rosaceae" do not contain phloridzin. Phloridzin is a phytochemical that belongs to the class
Karl Malus who runs IGH, a biotech clinic that specializes in state-of-the-art reconstructive surgery. When Jessica Jones and her mother Alisa are critically injured in a car accident, Dr. Malus arranges for them to be siphoned from Metro-General Hospital to his clinic so he can save their lives. Jessica gets released after about three weeks, while Alisa's recovery takes several more years due to more extensive damage. Over the course of treating her, Dr. Malus develops romantic feelings for Alisa, and even covers up her accidental killing of one of his nurses by having a janitor take the fall for the crime.