Rhinitis medicamentosa and nasal edema. Evidence suggests that if oxymetazoline is used only nightly for allergic rhinitis (instead of more frequent dosage as may be directed on product label), it may be used longer than one week without high risk of rhinitis medicamentosa especially with use of intranasal steroid like fluticasone furoate. The treatment of RM involves withdrawal of the offending nasal spray or oral medication. Both a "cold turkey" and a "weaning" approach can be used. Cold turkey is the most effective treatment method, as it directly removes the cause of the condition, yet the time period between the discontinuation of
Seasonal adjustment data can be misleading. This is because the seasonally adjusted series contains both the trend-cycle component and the error component. As such, the seasonally adjusted data will not be "smooth" and what appears to be "downturns" or "upturns" may actually be randomness in the data. For this reason, if the purpose is finding turning points in a series, it is better to use the trend-cycle component rather than the seasonally adjusted data. Seasonal adjustment Seasonal adjustment is a statistical method for removing the seasonal component of a time series that exhibits a seasonal pattern. It is usually done when wanting