Benzylpenicillin of penicillin allergy. Use during pregnancy is generally safe. It is in the penicillin and β-lactam class of medications. Benzylpenicillin was discovered in 1929 by Alexander Fleming and came into commercial use in 1942. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about US$0.24–2.72 per day. In the United States a course of treatment costs $100–200. As an antibiotic, benzylpenicillin is noted to possess effectiveness mainly against Gram-positive organisms. Some Gram-negative organisms such as "Neisseria gonorrhoeae" and "Leptospira
Saint Valentine of the emperor Claudius and secretly married couples so that the husbands wouldn't have to go to war. The legend claims that soldiers were sparse at this time so this was a big inconvenience to the emperor. Another legend is that Valentine refused to sacrifice to pagan gods. Being imprisoned for this, Valentine gave his testimony in prison and through his prayers healed the jailer's daughter who was suffering from blindness. On the day of his execution he left her a note that was signed, "Your Valentine". Saint Valentine was not exceptionally more venerated than other saints and it seems