Extrachromosomal Circular DNA are composed of chromatin and replicate in the nucleus of the cell during cell division. Unlike typical chromosomes, they are composed of circular fragments of DNA, up to only a few million base pairs in size and contain no centromere or telomere. Extrachromosomal Circular DNA Extrachromosomal circular DNA (eccDNA) is circular DNA found in the nuclei of plant and animal cells, including human cells, in addition to chromosomal DNA. eccDNA can be from 200 up to 5 million base pairs in length. eccDNA has been found in the nuclei of human cancer cells and shown to carry many copies of
Genomic DNA by RNA Polymerase III. Genomic DNA Genomic deoxyribonucleic acid is chromosomal DNA, in contrast to extra-chromosomal DNAs like plasmids. It is also then abbreviated as gDNA. Most organisms have the same genomic DNA in every cell; however, only certain genes are active in each cell to allow for cell function and differentiation within the body. The genome of an organism (encoded by the genomic DNA) is the (biological) information of heredity which is passed from one generation of organism to the next. That genome is transcribed to produce various RNAs, which are necessary for the function of the organism. Precursor