Red blood cell macrophages and subsequent phagocytosis in the mononuclear phagocyte system (spleen, liver and lymph nodes), thus removing old and defective cells and continually purging the blood. This process is termed eryptosis, red blood cell programmed cell death. This process normally occurs at the same rate of production by erythropoiesis, balancing the total circulating red blood cell count. Eryptosis is increased in a wide variety of diseases including sepsis, haemolytic uremic syndrome, malaria, sickle cell anemia, beta-thalassemia, glucose-6-phosphate dehydrogenase deficiency, phosphate depletion, iron deficiency and Wilson's disease. Eryptosis can be elicited by osmotic shock, oxidative stress, energy depletion as well as a
Red as Blood, or Tales from the Sisters Grimmer Red as Blood, or Tales from the Sisters Grimmer Red as Blood, or Tales from the Sisters Grimmer is a short story collection of dark fantasy retellings of popular fairytales by British author Tanith Lee. Contrary to what the title may suggest, it not only includes retellings of fairytales by the Brothers Grimm, but also by Charles Perrault, Gabrielle-Suzanne Barbot de Villeneuve or Alexander Afanasyev. The title story was nominated for a Nebula Award. "Red as Blood, or Tales from the Sisters Grimmer" contains the following tales: In 2014, the book was released as an expanded edition including a new