Protein signalling in heart development Protein signalling in heart development The heart is the first functional organ in a vertebrate embryo. There are 5 stages to heart development. Specification of cardiac precursor cells: The lateral plate mesoderm delaminates to form two layers: the dorsal somatic (parietal) mesoderm and the ventral splanchnic (visceral) mesoderm. The heart precursor cells come from the two regions of the splanchnic mesoderm called the cardiogenic mesoderm. These cells can differentiate into endocardium which lines the heart chamber and valves and the myocardium which forms the musculature of the ventricles and the atria. The heart cells are specified in anterior mesoderm by
How Many Fucks of "Los Angeles Magazine" called the song "an instant classic" and "amazing". A music video for "How Many Fucks" was released on April 19, 2016 and directed by Mikey Minden. In the video, Jayne wears several "rather risqué" costumes, including a "money-print dress" and shimmery clothing to appear as a "golden goddess". According to E! Online, several of the dance moves performed are not safe for work. Evan Real of "Us Weekly" described the video as Jayne "show[ing] off her killer curves in a variety of skin-baring ensembles as she cavorts across mini-movie's several sets." The video opens with Jayne