Leg hair follicle it pushed older cells out and that is what becomes the leg hair. After the older cells become hard and leave the follicle, they form a hair shaft. The hair shaft is mostly made up of dead tissue and a protein that is known as keratin. It is said that hair growth occurs during the "growing" phase of the follicle, and then retained as dead club hair during the "resting" phase. The old club hair might be lost within the following "growing" phase. Men are seen to be much hairier than women, even though men and women are much
MPLKIP of the hairs. Only a minority of the TTD cases carry a MPLKIP defect: more frequently, the gene ERCC2 is mutated, which encodes a subunit of the protein complex TFIIH that is required for general transcription and for nucleotide excision repair of DNA damage. MPLKIP M-phase-specific PLK1-interacting protein (TTD non-photosensitive 1 protein) is a protein that in humans is encoded by the MPLKIP gene (previously known as C7orf11). Patients with an inherited defect in both alleles of the gene suffer from trichothiodystrophy (TTD), a disease hallmarked by brittle hair and nails and usually by developmental difficulties as well. One patient