Broad-spectrum antibiotic their greater potential to disrupt a larger variety of normal human flora. After continued exposure to an antibiotic, bacteria may develop changes in their structure or function that make them resistant to the antibiotic. These resistant organisms will live, while the susceptible organisms will die, leaving the population of bacteria entirely resistant to a given antibiotics. For example, after the discovery of penicillin and its subsequent use to treat bacterial infections, bacteria were found to have begun producing an enzyme, penicillinase, which rendered the penicillin molecule inactive. In response to this newly-acquired resistance, newer penicillins were produced that could not
Antibiotic-Antimycotic reproductive techniques. In animal cell culture, Antibiotic-Antimycotic solution was used to wash goat embryos prior to incubation with oviduct and uterine cells, for enhanced development of embryos into blastocysts. In large-scale bioreactors, contamination risk is high due to the connection of tubing from inlets and outlets. Antibiotic-Antimycotic solution was incorporated into media for culturing suspension-adapted human embryonic kidney (HEK) 293 cell lines in bioreactors. The ability to isolate cell types is an important component of tissue engineering. In order to prevent contamination during seeding of human fibroblasts followed by endothelial cells on polymeric scaffolds, Antibiotic-Antimycotic solution was used during the