Versican other inflammatory cells) can migrate more easily through extracellular matrix that has a higher versican content. Deposits of versican are not present in normal skin but are found in the reticular dermis during keloid scarring, a condition where scar formation becomes uncontrolled and overgrowth of skin tissue occurs at the site of the wound. Versican has been shown to interact with hyaluronan and a link protein (hyaluronan and proteoglycan link protein 1; HAPLN1). Versican Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissues. It is encoded by the "VCAN" gene. Versican is a
Leaf scar quickly healed over with protective cork. Stipules may also leave their own scars if they are present. Bundle scars are circular or barred regions within the leaf scar where bundles of vascular tissue that had connected the leaf and the stem broke off. The number of bundle scars in a leaf scar is sometimes used as an identifying mark as they are often consistent across a species. Leaf scar A leaf scar is the mark left by a leaf after it falls off the twig. It marks the site where the petiole attached to the stem. A leaf scar is