State microbe is noteworthy because it is: the first significant antibiotic discovered after penicillin; the first systemic antibiotic discovered in America; the first antibiotic active against tuberculosis; first-line treatment for plague. Moreover, New Jersey was the home of Selman Waksman, who was awarded the Nobel Prize in Physiology or Medicine for his systematic studies of antibiotic production by "S. griseus" and other soil microbes. On May 15, 2017, Senate Bill 3190 (S3190) was introduced by Senator Samuel D. Thompson (R-12); the bill designates "Streptomyces griseus" as the New Jersey State Microbe, to be added to the state's other state symbols. On June
Antibiotic the responsible pathogen has not been identified, an empiric therapy is adopted. This involves the administration of a broad-spectrum antibiotic based on the signs and symptoms presented and is initiated pending laboratory results that can take several days. When the responsible pathogenic microorganism is already known or has been identified, definitive therapy can be started. This will usually involve the use of a narrow-spectrum antibiotic. The choice of antibiotic given will also be based on its cost. Identification is critically important as it can reduce the cost and toxicity of the antibiotic therapy and also reduce the possibility of the