Blood gas tension Blood gas tension Blood gas tension refers to the partial pressure of gases in blood. There are several significant purposes for measuring gas tension; the most common gas tensions measured are oxygen tension (PO), the carbon dioxide tension (PCO) and carbon monoxide tension (PCO). The subscript "x" in each symbol represents the source of the gas being measured; ""a"" meaning arterial, ""A"" being alveolar, ""v"" being venous, ""c"" being capillary. Blood gas tests (such as arterial blood gas tests) measure these partial pressures. PO – Partial pressure of oxygen at sea level (765 mmHg) in arterial blood is between 75
Hemoglobin The iron atom in the heme group must initially be in the ferrous (Fe) oxidation state to support oxygen and other gases' binding and transport (it temporarily switches to ferric during the time oxygen is bound, as explained above). Initial oxidation to the ferric (Fe) state without oxygen converts hemoglobin into "hemiglobin" or methemoglobin, which cannot bind oxygen. Hemoglobin in normal red blood cells is protected by a reduction system to keep this from happening. Nitric oxide is capable of converting a small fraction of hemoglobin to methemoglobin in red blood cells. The latter reaction is a remnant activity of