Biconcave disc characteristic red color and transport oxygen from the lungs to the tissues. Mature red blood cells are round and biconcave because they lack a nucleus and unlike other cells, red cells require a small amount of oxygen for its metabolism and most oxygen is freed into the tissues. The absence of nucleus, ribosomes, and mitochondria partly contributes to the red blood cell’s disc-like structure which leaves room for hundreds of millions of hemoglobin molecules found within the cells. Hemoglobin is a red and iron-rich protein that merges with oxygen to carry oxygen from the lungs to the body tissues. Both
Packed red blood cells red cells with both are called AB. Except in unusual cases like infants or seriously immunocompromised individuals, all people will have antibodies to any ABO blood type that isn't present on their own red blood cells, and will have an immediate hemolytic reaction to a unit that is not compatible with their ABO type. In addition to the A and B antigens, there are rare variations which can further complicate transfusions, such as the Bombay phenotype. The Rh blood group system consists of nearly around 50 different antigens, but the one of the greatest clinical interest is the "D" antigen,