John Jacob Abel to successfully isolate the neutral base of epinephrine by adding ammonium to highly concentrated extract, a method Abel himself tried but failed due to the use of low concentration of extract. After Takamine's success, Abel himself remarked, with great candor, "The efforts of years on my part in this once mysterious field of suprarenal, medullary biochemistry, marred by blunders as they were, eventuated, then, in the isolation of the hormone not in the form of the free base but in that of its monobenzoyl derivative." Together with L.G. Rowntree and B.B. Turner, Abel devised what they called a "vividiffusion" apparatus,
John Abel but there is no record of his second wife except on his table tomb in Sarnesfield. He had one son, named John, who later became churchwarden of Sarnesfield. Very little is known about Abel's work, and some local traditions attribute buildings to him that are impossible in terms of their date. Abel's first known commission was in 1625 when he was contracted to build Lady Hawkins' grammar school in Kington. The contract was to fit into the terms of the will of Lady Margaret Hawkins. It is known that Abel supplied all the materials and that he was paid £240.