Relapse levels and a decrease in estradiol levels during the luteal phase. Anxiety, irritability, and depression, three symptoms of both withdrawal and the human menstrual cycle, are most severe in the luteal phase. Symptoms of withdrawal not associated with the cycle, such as hunger, are also enhanced during the luteal phase, which suggests the role of estradiol and progesterone in enhancing symptoms above the naturally occurring level of the menstrual cycle. The symptoms of craving also increase during the luteal phase in humans (it is important to note that the opposite result occurs in female subjects with cocaine addiction suggesting that
Menstrual cycle extra-pair flirtations and demonstrate a preference for extra pair copulation. Preferences for voice pitch change across the cycle. When seeking a short term mating partner, women may prefer a male with a low voice pitch, particularly during the fertile phase. During the late follicular phase, it is common for women demonstrate a preference for mates with a masculine, deep voice. Research has also been conducted on the attractiveness of the female voice throughout the cycle. During their most fertile phase of the menstrual cycle, there is some evidence that female voices are rated as significantly more attractive. This effect is