Glycogen storage disease type 0 pallor. Uncoordinated eye movements, disorientation, seizures, and coma may accompany severe episodes. Glycogen-storage disease type 0 affects only the liver. Growth delay may be evident with height and weight percentiles below average. Abdominal examination findings may be normal or reveal only mild hepatomegaly.Signs of acute hypoglycemia may be present, including the following: Glycogen-storage disease type 0 is caused by genetic defects in the gene that codes for liver glycogen synthetase (GYS2), which is located on chromosome band 12p12.2. Glycogen synthetase catalyzes the rate-limiting reaction for glycogen synthesis in the liver by transferring glucose units from uridine 5'-diphosphate (UDP)-glucose to a
Wanamaker Organ This level of dedication was maintained when corporate parentage shifted from the Wanamaker family to Carter Hawley Hale Stores followed by Woodward & Lothrop, The May Department Stores Company, Lord & Taylor, and finally to Macy's. The Wanamaker Organ was originally built by the Los Angeles Art Organ Company, successors to the Murray M. Harris Organ Co., for the 1904 St. Louis World's Fair. It was designed to be the largest organ in the world, an imitation of a full-size orchestra with particularly complete resources of full organ tone including mixtures. In addition to its console, the organ was originally