Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian Ruminski Castle", featuring the glass sculptures of Dale Chihuly. In 2017, Ruminski received Opera America's Bravo Service Award, whose recipients "promote opera in their communities and work tirelessly to ensure the highest possible artistic quality and community service." Ruminski's opera performances have included, among others: Ruminski's concert and recital performances have included, among others: Ruminski's recordings include: Valerian Ruminski Valerian Ruminski (born 1967) is an American operatic bass. He is also the founder and artistic director of Nickel City Opera, in Buffalo, New York. Named Martin Matthew Ruminski by his adoptive parents Mary and Valerian Ruminski, he was born in Lackawanna,