Transgender hormone therapy (male-to-female) males is associated with higher serum estrogen. Both estrogen and testosterone help to stimulate bone formation, especially during puberty. Estrogen is the predominant sex hormone that slows bone loss, even in men. In spite of the induction of breast development, transgender women who undergo HRT do not have an increased risk of breast cancer. Only a handful of cases of breast cancer have ever been described in transgender women who have undergone male-to-female HRT. This is in accordance with research in cisgender men in which gynecomastia has been found not to be associated with an increased risk of breast cancer,
Asia Pacific Coalition on Male Sexual Health Nations officials. Its mission is to assist local organizations in advocacy for the rights of MSMs and transgender males. Asia Pacific Coalition on Male Sexual Health The Asia Pacific Coalition on Male Sexual Health, also known as APCOM, is a network of non-profit organizations which share the mission of improving male sexual health in South Asia, East Asia, and the Pacific Islands. APCOM was launched in July 2007 after delegates to the Delhi 2006 International Consultation on Male Sexual Health and HIV in Asia and the Pacific identified a need for more organization in the field of male sexual health.