Apparent mineralocorticoid excess syndrome cases recorded worldwide. Liquorice consumption may also cause a temporary form of AME due to its ability to block 11β-hydroxysteroid dehydrogenase type 2, in turn causing increased levels of cortisol. Cessation of licorice consumption will reverse this form of AME. Apparent mineralocorticoid excess syndrome Apparent mineralocorticoid excess (AME) is an autosomal recessive disorder causing hypertension (high blood pressure) and hypokalemia (abnormally low levels of potassium). It was found by Dr Maria I. New at Weil Cornell Hospital in New York City. It results from mutations in the "HSD11B2" gene, which encodes the kidney isozyme of 11β-hydroxysteroid dehydrogenase type 2. In
The Mud, Water, Air & Blood on July 29, 2014, but will initially be released at the 2014 GOTJ. The Mud, Water, Air & Blood The Mud, Water, Air & Blood is the fourth and final studio album by Dark Lotus. The album was released on July 29, 2014. In a February 2014 interview with Faygoluvers.net Insane Clown Posse announced that they were getting ready to hit the studio and record a Dark Lotus album in 2014. On March 12, 2014, Insane Clown Posse, Twiztid and Blaze Ya Dead Homie's media outlets a picture was posted by each one with the DL sign and roman numerals