Pacemaker current on hyperpolarization, and very slow kinetics. The funny current is highly expressed in spontaneously active cardiac regions, such as the sinoatrial node (SAN, the natural pacemaker region), the atrioventricular node (AVN) and the Purkinje fibres of conduction tissue. The funny current is a mixed sodium–potassium current that activates upon hyperpolarization at voltages in the diastolic range (normally from −60/−70 mV to −40 mV). When, at the end of a sinoatrial action potential, the membrane repolarizes below the I threshold (about −40/−50 mV), the funny current is activated and supplies inward current, which is responsible for starting the diastolic depolarization phase
Orbital node terms αναβιβάζων and καταβιβάζων were also used for the ascending and descending nodes, giving rise to the English words "anabibazon" and "catabibazon". For the orbit of the Moon around Earth, the plane is taken to be the ecliptic, not the equatorial plane. The gravitational pull of the Sun upon the Moon causes its nodes to gradually precess westward, completing a cycle in approximately 18.6 years. Orbital node An orbital node is either of the two points where an orbit intersects a plane of reference to which it is inclined. A non-inclined orbit, which is contained in the reference plane, has