Thioglycolic acid corresponding disulfide (2-[(carboxymethyl)disulfanyl]acetic acid or dithiodiglycolic acid): Thioglycolic acid, usually as its dianion, forms complexes with metal ions. Such complexes have been used for the detection of iron, molybdenum, silver, and tin. Thioglycolic acid reacts with diethyl acetylmalonate to form acetylmercaptoacetic acid and diethyl malonate, the reducing agent in conversion of Fe(III) to Fe(II). Scientist David R. Goddard, in the early 1930s, identified TGA as a useful reagent for reducing the disulfide bonds in proteins, including keratin (hair protein), while studying why protease enzymes could not easily digest hair, nails, feathers, and such. He realized that while the disulfide bonds,
Artificial nails Over time, exposure to MMA could cause lasting effects such as drowsiness, light-headedness, and trembling of the hands. Musicians who play stringed instruments may wear artificial nails as an aid in playing. Some guitarists like Don Ross, Doyle Dykes and James Taylor are known for doing so. Many intermediate and advanced classical and finger-style guitarists use varieties of fake nails to obtain a consistent, clear and bright tone with each pluck. The players of many ancient Chinese instruments, like the guqin, pipa, and ruan, also commonly used artificial nails. Even the Indian instrument sarod requires nails for tipping, so many