Exercise physiology loss of integrity to the blood brain barrier. Hyperthermia also can lower cerebral blood flow, and raise brain temperature. Researchers once attributed fatigue to a build-up of lactic acid in muscles. However, this is no longer believed. Rather, lactate may stop muscle fatigue by keeping muscles fully responding to nerve signals. The available oxygen and energy supply, and disturbances of muscle ion homeostasis are the main factor determining exercise performance, at least during brief very intense exercise. Each muscle contraction involves an action potential that activates voltage sensors, and so releases Ca ions from the muscle fibre’s sarcoplasmic reticulum. The
Internal intercostal muscles such as coughing or during exercise and not in relaxed breathing. The external intercostal muscles, and the intercartilaginous part of the internal intercostal muscles, (the part of the muscle that lies between the cartilage portion of the superior and inferior ribs), are used in inspiration, by aiding in elevating the ribs and expanding the thoracic cavity. Internal intercostal muscles The internal intercostal muscles (intercostales interni) are a group of skeletal muscles located between the ribs. They are eleven in number on either side. They commence anteriorly at the sternum, in the intercostal spaces between the cartilages of the true ribs,