Thioglycolic acid corresponding disulfide (2-[(carboxymethyl)disulfanyl]acetic acid or dithiodiglycolic acid): Thioglycolic acid, usually as its dianion, forms complexes with metal ions. Such complexes have been used for the detection of iron, molybdenum, silver, and tin. Thioglycolic acid reacts with diethyl acetylmalonate to form acetylmercaptoacetic acid and diethyl malonate, the reducing agent in conversion of Fe(III) to Fe(II). Scientist David R. Goddard, in the early 1930s, identified TGA as a useful reagent for reducing the disulfide bonds in proteins, including keratin (hair protein), while studying why protease enzymes could not easily digest hair, nails, feathers, and such. He realized that while the disulfide bonds,
Hair plexus Hair plexus A hair plexus or root hair plexus is a special group of nerve fiber endings and serves as a very sensitive mechanoreceptor for touch sensation. Each hair plexus forms a network around a hair follicle and is a receptor, which means it sends and receives nerve impulses to and from the brain when the hair moves. Endings of sensory nerve fibers which form a plexus around a hair follicle in hairy skin. They are mechanoreceptors conveying touch sensation. Specifically, crude touch and pressure sensation conveyed through the spinocervical tract, which is located in the posterior part of the