Human tooth development the low levels of fluoride incorporation and very mild fluorosis makes the tooth more resistant to demineralization and subsequent decay. Deficiencies of nutrients can have a wide range of effects on tooth development. In situations where calcium, phosphorus, and vitamin D are deficient, the hard structures of a tooth may be less mineralized. A lack of vitamin A can cause a reduction in the amount of enamel formation. Fluoride ingestion has been noted to delay eruption of teeth for as much as a year or more from the accepted eruption dates since the initial 1940s fluoridation trials. Researchers theorize that
Tooth whitening filling the root canal with gutta-percha points, cleaning the inside of the canal using etchant and placing a peroxide gel or sodium perborate tetrahydrate into the pulp chamber so they can work directly inside the tooth on the dentine layer. In this variation of whitening the whitening agent is sealed within the tooth over a period of some days and replaced as needed, the so-called "walking bleach" technique.. A seal should be placed over the root filling material to minimise microleakage. There is a small risk of external resorption. An alternative to the walking bleach procedure is the inside-out bleach