Glycogen phosphorylase concentration, as the liver acts as a glucose exporter. In essence, liver phosphorylase is responsive to glucose, which causes a very responsive transition from the R to T form, inactivating it; furthermore, liver phosphorylase is insensitive to AMP. Glycogen phosphorylase was the first allosteric enzyme to be discovered. This accomplishment was one of many landmark achievements made by Carl and Gerty Cori. In 1943, with the help of Arda Green, the pair illustrated that glycogen phosphorylase existed in either the or b forms depending on its phosphorylation state, as well as in the R or T states based on the
The body in traditional Chinese medicine of all the Yin and Yang energy in the body. The Kidneys also govern the endocrine system, receive air from the lungs, govern bones, govern teeth, control water in the body, and store essence. Dysfunction of the Kidneys leads to deficiencies of Yin or Yang. It also leads to imbalanced hormones, weak bones, an impaired sex drive, and dizziness. Water in excess leads to bipolar disorder. Depressive episodes are characterized by Kidney Yin excess while manic episodes are characterized by Kidney Yang excess. The Kidney Meridian begins on the sole, moves up the inner leg to the groin, up the