Versican other inflammatory cells) can migrate more easily through extracellular matrix that has a higher versican content. Deposits of versican are not present in normal skin but are found in the reticular dermis during keloid scarring, a condition where scar formation becomes uncontrolled and overgrowth of skin tissue occurs at the site of the wound. Versican has been shown to interact with hyaluronan and a link protein (hyaluronan and proteoglycan link protein 1; HAPLN1). Versican Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissues. It is encoded by the "VCAN" gene. Versican is a
Scar Tissue New Zealand and Canada, where it reached numbers three and four, respectively. "Scar Tissue" is considered to be representative of the new, more melodic rock sound the band experimented with on "Californication" (in contrast to the psychedelic "One Hot Minute", and dry funk of "Blood Sugar Sex Magik"). The song is notable for its mellow intro guitar riff and for its slide guitar solos throughout. "Guitar World" placed the guitar solo 63rd in its list of the "100 Greatest Guitar Solos". "Scar Tissue" won a Grammy Award for Best Rock Song in 2000. In 2004, Anthony Kiedis published "Scar Tissue".