Human tooth development the formation of odontoblasts continue from the tips of the cusps, the odontoblasts secrete a substance, an organic matrix, into their immediate surrounding. The organic matrix contains the material needed for dentin formation. As odontoblasts deposit organic matrix termed predentin, they migrate toward the center of the dental papilla. Thus, unlike enamel, dentin starts forming in the surface closest to the outside of the tooth and proceeds inward. Cytoplasmic extensions are left behind as the odontoblasts move inward. The unique, tubular microscopic appearance of dentin is a result of the formation of dentin around these extensions. After dentin formation begins,
Radius of outermost closed isobar Radius of outermost closed isobar The radius of outermost closed isobar (ROCI) is one of the quantities used to determine the size of a tropical cyclone. It is determined by measuring the radii from the center of the storm to its outermost closed isobar in four quadrants, which is then averaged to come up with a scalar value. It generally delimits the outermost extent of a tropical cyclone's wind circulation. Use of this measure has objectively determined that tropical cyclones in the northwest Pacific Ocean are the largest on earth on average, with North Atlantic tropical cyclones roughly half their