Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
Acid rock Acid rock Acid rock is a loosely defined type of rock music that evolved out of the mid-1960s garage punk movement and helped launch the psychedelic subculture. The style is generally defined by heavy, distorted guitars, lyrics with drug references, and long improvised jams. Its distinctions from other genres can be tenuous, as much of the style overlaps with '60s punk, proto-metal, and early heavy, blues-based hard rock. The term, which derives its name from lysergic acid diethylamide (LSD), is sometimes used interchangeably with "psychedelic rock", but may refer more specifically to a more musically intense subgenre or sibling to