Glycogen phosphorylase the site at which the enzyme binds to glycogen granules before initiating cleavage of terminal glucose molecules. In fact, 70% of dimeric phosphorylase in the cell exists as bound to glycogen granules rather than free floating. The inhibition of glycogen phosphorylase has been proposed as one method for treating type 2 diabetes. Since glucose production in the liver has been shown to increase in type 2 diabetes patients, inhibiting the release of glucose from the liver’s glycogen’s supplies appears to be a valid approach. The cloning of the human liver glycogen phosphorylase (HLGP) revealed a new allosteric binding site near
Love in Excess; or, The Fatal Enquiry included several prefatory poems. The poems flatter Haywood's narrative skills and her ability to present "the power of physical and emotional love". The poems that were published in the early editions praised "Love in Excess", but in the 6 edition, they also noticed Haywood's body of work, suggesting her higher reputation as a writer. Positive reaction to her work influenced more women to publish. (109-110) Love in Excess; or, The Fatal Enquiry Love in Excess (1719–1720) is Eliza Haywood's best known novel. It details the amorous escapades of Count D'Elmont, a rake who becomes reformed over the course of the