Progesterone nervous tissue, especially in the brain, and in adipose (fat) tissue, as well. During human pregnancy, progesterone is produced in increasingly high amounts by the ovaries and placenta. At first, the source is the corpus luteum that has been "rescued" by the presence of human chorionic gonadotropin (hCG) from the conceptus. However, after the 8th week, production of progesterone shifts to the placenta. The placenta utilizes maternal cholesterol as the initial substrate, and most of the produced progesterone enters the maternal circulation, but some is picked up by the fetal circulation and used as substrate for fetal corticosteroids. At term
Menstrual synchrony one menstrual onset for each woman in a couple, they calculated the degree of synchrony. They reported that more than half of the couples had synchronized within a two-day timespan of each other. Trevathan, Burleson, and Gregory also conducted a study with 29 lesbian couples (22 to 48 years of age), but they incorporated the methodological critique of Wilson into the design of their study. In particular, Wilson emphasized the importance of using actual menstrual cycle lengths with their inherent variability. The lesbian couples were drawn from a larger sample of women who had kept daily records of their menstrual