Recreational drug use are caused by an excessive response of the body to allergens, such as the pollen released by grasses and trees. An allergic reaction causes release of histamine by the body. Other uses of antihistamines are to help with normal symptoms of insect stings even if there is no allergic reaction. Their recreational appeal exists mainly due to their anticholinergic properties, that induce anxiolysis and, in some cases such as diphenhydramine, chlorpheniramine, and orphenadrine, a characteristic euphoria at moderate doses. High dosages taken to induce recreational drug effects may lead to overdoses. Antihistamines are also consumed in combination with alcohol, particularly
Fabio Cannavaro during periods of anoxia and stress. It is not on the banned substance list. This chemical is, in partnership with adenosine triphosphate (ATP), fundamental to the ability of the body to produce muscular energy. Phosphocreatine is formed naturally within the body, with over 95% of the compound stored within the muscle cells. The body also receives dietary creatine primarily through the consumption of meat. No action was ever taken regarding this incident. On 8 October 2009, Cannavaro failed a drug test. However, Juventus claimed the drugs were medicine for a severe allergic reaction to a wasp sting, and not performance-enhancing.