Peripheral blood mononuclear cell been thought to be an important route of vaccination. PBMCs from cancer patients can be extracted and cultured "in vitro". Subsequently, PBMCs are challenged with tumor antigens such as tumor stem cell antigen. Inflammatory cytokines are usually added to aid in antigen uptake and recognition by PBMCs. Peripheral blood mononuclear cell A peripheral blood mononuclear cell (PBMC) is any peripheral blood cell having a round nucleus. These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei. In humans, lymphocytes make up
White blood cell underlying cause, though the cause may not always be found. The complete blood cell count is a blood panel that includes the overall WBC count and various subsets such as the absolute neutrophil count. Reference ranges for blood tests specify the typical counts in healthy people. TLC- (Total leucocyte count): Normal TLC in an adult person is 6000-8000WBC/mm^3 of blood. DLC- (Differential leucocyte count): Number/ (%) of different type of leucocyte in per cubic mm. of blood. White blood cell White blood cells (also called leukocytes or leucocytes and abbreviated as WBCs) are the cells of the immune system that