Transgender hormone therapy (male-to-female) males is associated with higher serum estrogen. Both estrogen and testosterone help to stimulate bone formation, especially during puberty. Estrogen is the predominant sex hormone that slows bone loss, even in men. In spite of the induction of breast development, transgender women who undergo HRT do not have an increased risk of breast cancer. Only a handful of cases of breast cancer have ever been described in transgender women who have undergone male-to-female HRT. This is in accordance with research in cisgender men in which gynecomastia has been found not to be associated with an increased risk of breast cancer,
Sexual desire and intimate relationships primary goal of sexual desire. It has also been suggested that women are more likely than men to develop a “relational” or “person-centered” orientation to sexual desire, whereas men are more likely to adopt a “recreational” or “body-centered” orientation to sexuality. These results further support the suggestion that despite generally consistent definitions of sexual desire, perceived differing end goals of sexual desire may exist between the sexes. In keeping with providing definitions of sexual desire consistent with those of theorists, both men and women have consistently expressed their beliefs that the causes of male sexual desire differ from female causes