Atmosphere of Earth International Space Station orbits in this layer, between . The mesosphere is the third highest layer of Earth's atmosphere, occupying the region above the stratosphere and below the thermosphere. It extends from the stratopause at an altitude of about to the mesopause at above sea level. Temperatures drop with increasing altitude to the mesopause that marks the top of this middle layer of the atmosphere. It is the coldest place on Earth and has an average temperature around . Just below the mesopause, the air is so cold that even the very scarce water vapor at this altitude can be
Ozone depletion from the 250 recorded over central Siberia. It is predicted that the thinning layer would affect parts of Scandinavia and Eastern Europe on March 30–31. On October 2, 2011, a study was published in the journal "Nature", which said that between December 2010 and March 2011 up to 80 percent of the ozone in the atmosphere at about above the surface was destroyed. The level of ozone depletion was severe enough that scientists said it could be compared to the ozone hole that forms over Antarctica every winter. According to the study, "for the first time, sufficient loss occurred to