Tendon the presence of denatured collagen are factors that are believed to cause weakening of the tendon ECM and an increase in the potential for another rupture to occur. In response to repeated mechanical loading or injury, cytokines may be released by tenocytes and can induce the release of MMPs, causing degradation of the ECM and leading to recurring injury and chronic tendinopathies. A variety of other molecules are involved in tendon repair and regeneration. There are five growth factors that have been shown to be significantly upregulated and active during tendon healing: insulin-like growth factor 1 (IGF-I), platelet-derived growth factor
Tendon reflex Tendon reflex Tendon reflex (or T-reflex) may refer to: To test the reflex, tap on the tendon. In a healthy individual the intensity on both sides is equal. This means that the connections between the spinal cord and the muscles are undamaged. Main Spinal Nerve Roots Involved: The Golgi tendon reflex is a response to extensive tension on a tendon. It helps avoid strong muscle contractions which could tear the tendon from either the muscle or bone. In sports, quick movements can damage the tendon before the reflex can occur. The tendon reflex also helps spread the workload more evenly