Versican other inflammatory cells) can migrate more easily through extracellular matrix that has a higher versican content. Deposits of versican are not present in normal skin but are found in the reticular dermis during keloid scarring, a condition where scar formation becomes uncontrolled and overgrowth of skin tissue occurs at the site of the wound. Versican has been shown to interact with hyaluronan and a link protein (hyaluronan and proteoglycan link protein 1; HAPLN1). Versican Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissues. It is encoded by the "VCAN" gene. Versican is a
Dense regular connective tissue in DCRT elastic fibers are completely absent. Dense regular connective tissue has great tensile strength that resists pulling forces especially well in one direction. DRCT has a very poor blood supply, which is why damaged tendons and ligaments are slow to heal. Dense regular connective tissue Dense regular connective tissue provides connection between different tissues in the human body. The collagen fibers in dense regular connective tissue are bundled in a parallel fashion. Dense regular connective tissue (DRCT) is divided into white fibrous connective tissue and yellow fibrous connective tissue, both of which occur in two forms: cord arrangement and