Tympanic cavity of infection or for some other reason, it can be drained by puncturing the tympanic membrane with a large bore needle (tympanocentesis). Tympanic cavity The tympanic cavity is a small cavity surrounding the bones of the middle ear. Within it sit the ossicles, three small bones that transmit vibrations used in the detection of sound. On its lateral surface, it abuts the external auditory meatus [ ear canal ] from which it is separated by the tympanic membrane (eardrum). The tympanic cavity is bounded by: It is formed from the tubotympanic recess, an expansion of the first pharyngeal pouch. If
Membrane curvature several amphipathic alpha helices that allows it to partition between the hydrophobic core of the membrane and surrounding aqueous, hydrophilic environment. Another interesting characteristic of epsin and other proteins that bind to membranes is the fact that it shows high binding affinity for a fairly common membrane lipid, phosphatidylinositol 4,5-bisphosphate (PI-4,5-P2). Unlike other proteins that simply bend the membrane through sheer rigidity, epsin is a globular soluble protein and thus not rigid. The insertion of its helices into the membrane force the neighboring lipids of the leaflet that has been bound to expand laterally. This displacement of lipids on only