Red blood cell blood circulation for about 100 to 120 days (and 80 to 90 days in a full term infant). At the end of their lifespan, they are removed from circulation. In many chronic diseases, the lifespan of the red blood cells is reduced. Erythropoiesis is the process by which new red blood cells are produced; it lasts about 7 days. Through this process red blood cells are continuously produced in the red bone marrow of large bones. (In the embryo, the liver is the main site of red blood cell production.) The production can be stimulated by the hormone erythropoietin (EPO),
Blood red dark red state, but quickly oxygenates upon exposure to air, turning a brighter shade of red. This happens more quickly with smaller volumes of blood such as a pinprick and less quickly from cuts or punctures that cause greater blood flows such as a puncture in the basilic vein: all blood collected during a phlebotomy procedure is deoxygenated blood, and it does not usually have a chance to become oxygenated upon leaving the body. Arterial blood, which is already oxygenated, is also already a brighter shade of red— this is the blood see from a pulsating neck, arm, or leg