Sickle cell nephropathy Sickle cell nephropathy Sickle cell nephropathy is a type of nephropathy associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla, coupled with the slow blood flow in the vasa recta, favors sickling of red blood cells, with resultant local infarction (papillary necrosis). Functional tubule defects in patients with sickle cell disease are likely the result of partial ischemic injury to the renal tubules. Also the sickle cell disease in young patients is characterized by renal hyperperfusion,
Red as Blood, or Tales from the Sisters Grimmer Red as Blood, or Tales from the Sisters Grimmer Red as Blood, or Tales from the Sisters Grimmer is a short story collection of dark fantasy retellings of popular fairytales by British author Tanith Lee. Contrary to what the title may suggest, it not only includes retellings of fairytales by the Brothers Grimm, but also by Charles Perrault, Gabrielle-Suzanne Barbot de Villeneuve or Alexander Afanasyev. The title story was nominated for a Nebula Award. "Red as Blood, or Tales from the Sisters Grimmer" contains the following tales: In 2014, the book was released as an expanded edition including a new