Free-radical halogenation distribution". For propane and higher alkanes, the hydrogen atoms which form part of CH (or CH) groups are preferentially replaced. The reactivity of the different halogens varies considerably. The relative rates are: fluorine (108) > chlorine (1) > bromine (7 × 10) > iodine (2 × 10). Hence, the reaction of alkanes with fluorine is difficult to control, that with chlorine is moderate to fast, that with bromine is slow and requires high levels of UV irradiation while the reaction with iodine is practically nonexistent and thermodynamically unfavorable. A common method in organic synthesis employing is the Wohl–Ziegler reaction, which
Fluorine perchlorate and perchlorates, it needs to be handled with extreme caution. FClO is a strong oxidant and it reacts with iodide ion: FClO can also react with tetrafluoroethylene: It may be a radical addition reaction. Fluorine perchlorate Perchloryl Hypofluorite is the rarely encountered chemical compound of fluorine, chlorine, and oxygen with the chemical formula or . It is an extremely unstable gas that explodes spontaneously and has a penetrating odor. One synthesis uses fluorine and perchloric acid, though the action of ClF on water is another method. Another method of synthesis involves the thermal decomposition of tetrafluoroammonium perchlorate, , which yields