Human skin color within a "fair/medium/olive" context. Oculocutaneous albinism (OCA) is a lack of pigment in the eyes, skin and sometimes hair that occurs in a very small fraction of the population. The four known types of "OCA" are caused by mutations in the "TYR", "OCA2", "TYRP1", and "SLC45A2" genes. In hominids, the parts of the body not covered with hair, like the face and the back of the hands, start out pale in infants and turn darker as the skin is exposed to more sun. All human babies are born pale, regardless of what their adult color will be. In humans, melanin
Pigment Because of the expense of lapis lazuli, much effort went into finding a less costly blue pigment. Prussian blue was the first modern synthetic pigment, discovered by accident in 1704. By the early 19th century, synthetic and metallic blue pigments had been added to the range of blues, including French ultramarine, a synthetic form of lapis lazuli, and the various forms of Cobalt and Cerulean blue. In the early 20th century, organic chemistry added Phthalo Blue, a synthetic, organometallic pigment with overwhelming tinting power. Discoveries in color science created new industries and drove changes in fashion and taste. The discovery