Pacemaker current on hyperpolarization, and very slow kinetics. The funny current is highly expressed in spontaneously active cardiac regions, such as the sinoatrial node (SAN, the natural pacemaker region), the atrioventricular node (AVN) and the Purkinje fibres of conduction tissue. The funny current is a mixed sodium–potassium current that activates upon hyperpolarization at voltages in the diastolic range (normally from −60/−70 mV to −40 mV). When, at the end of a sinoatrial action potential, the membrane repolarizes below the I threshold (about −40/−50 mV), the funny current is activated and supplies inward current, which is responsible for starting the diastolic depolarization phase
Node B Node B Node B is the telecommunications node in particular mobile communication networks, namely those that adhere to the UMTS standard. The Node B provides the connection between mobile phones (UEs) and the wider telephone network. UMTS is the dominating 3G standard. Node B corresponds to BTS (base transceiver station) in GSM. This is the hardware that is connected to the mobile phone network that communicates directly with mobile handsets. In contrast with GSM base stations, Node B uses WCDMA/TD-SCDMA as the air interface technology. As in all cellular systems, such as UMTS and GSM, the Node B contains radio