Color vision are mixed together or diluted with white light, the number of distinguishable chromaticities can be quite high. In very low light levels, vision is scotopic: light is detected by rod cells of the retina. Rods are maximally sensitive to wavelengths near 500 nm, and play little, if any, role in colour vision. In brighter light, such as daylight, vision is photopic: light is detected by cone cells which are responsible for colour vision. Cones are sensitive to a range of wavelengths, but are most sensitive to wavelengths near 555 nm. Between these regions, mesopic vision comes into play and both
Retina bipolar cell inhibition and become active (depolarized), while the OFF bipolar cell loses its excitation (becomes hyperpolarized) and becomes silent. Rod bipolar cells do not synapse directly on to ganglion cells. Instead, rod bipolar cells synapse on to a Retina amacrine cell, which in turn excite cone ON bipolar cells (via gap junctions) and inhibit cone OFF bipolar cells (via glycine-mediated inhibitory synapses) thereby overtaking the cone pathway in order to send signals to ganglion cells at scotopic (low) ambient light conditions. OFF bipolar cells synapse in the outer layer of the inner plexiform layer of the retina, and ON bipolar cells