Rosalind Franklin and DNA best evidence for the structure of DNA. For the discovery of the correct chemical structure of DNA, the Nobel Prize in Physiology or Medicine 1962 was shared by her colleagues and close researchers James Watson, Francis Crick and Maurice Wilkins; she died four years earlier in 1958 making her inelligible for the award. Rosalind Franklin joined the King's College London in January 1951 to work on the crystallography of DNA. By the end of that year, she established two important facts: one is that phosphate groups, which are the molecular backbone for the nucleotide chains, lie on the outside (it
Solenoid (DNA) Solenoid (DNA) The solenoid structure of chromatin is a model for the structure of the 30 nm fibre. It is a secondary chromatin structure which helps to package eukaryotic DNA into the nucleus. Chromatin was first discovered by Walther Flemming by using aniline dyes to stain it. In 1974, it was first proposed by Roger Kornberg that chromatin was based on a repeating unit of a histone octamer and around 200 base pairs of DNA. The solenoid model was first proposed by John Finch and Aaron Klug in 1976. They used electron microscopy images and X-ray diffraction patterns to determine