Hyaline layer of Hopewell-Smith derivative proteins, such as Emdogain, in trying to stimulate reproduction of cementum in periodontal bony defects is based on the presence of enamel matrix-like proteins within the hyaline layer. Hyaline layer of Hopewell-Smith In tooth development, the hyaline layer of Hopewell-Smith is the most peripheral layer of initially unmineralized dentin that forms immediately subjacent to the cementodentinal junction (CDJ). It eventually mineralizes, but not before the rest of the dentin is already mineralized. It is 0.5-0.8 µm thick and contains enamel matrix-like protein as well as the proteins one would expect to find in dentin. It is into this hyaline
Tooth decay rarely does caries affect the cementum alone. Roots have a very thin layer of cementum over a large layer of dentin, and thus most caries affecting cementum also affects dentin. In the Western world, the primary approach to dental hygiene care consists of tooth-brushing and flossing. The purpose of oral hygiene is to remove and prevent the formation of plaque or dental biofilm. While evidence that flossing prevents tooth decay is limited, the practice is still generally recommended. As the amount of bacterial plaque increases, the tooth is more vulnerable to dental caries when carbohydrates in the food are left