Sugar Nutrition UK and water was 'as good as a glucose and water' at maintaining liver glycogen stores during prolonged exercise. Sugar Nutrition UK Sugar Nutrition UK formerly the British Sugar Bureau was a lobby group for the British sugar industry. Dr Alison Boyd is the director of the organisation. She says, in reply to proposals to tax sugar that "Singling out sugar may seem a simple, quick fix solution but risks ignoring many other factors that can contribute to lifestyle diseases.” According to the organisation "Sugar consumption in the UK has declined whilst obesity and diabetes rates have increased". It funded a
Glycogen phosphorylase the subunit interface that is not present in the rabbit muscle glycogen phosphorylase (RMGP) normally used in studies. This site was not sensitive to the same inhibitors as those at the AMP allosteric site, and most success has been had synthesizing new inhibitors that mimic the structure of glucose, since glucose-6-phosphate is a known inhibitor of HLGP and stabilizes the less active T-state. These glucose derivatives have had some success in inhibiting HLGP, with predicted Ki values as low as 0.016 mM. Mutations in the muscle isoform of glycogen phosphorylase (PYGM) are associated with glycogen storage disease type V (GSD