Chemical substance can be transmuted into another element through a nuclear reaction. This is so, because all of the atoms in a sample of an element have the same number of protons, though they may be different isotopes, with differing numbers of neutrons. As of 2012, there are 118 known elements, about 80 of which are stable – that is, they do not change by radioactive decay into other elements. Some elements can occur as more than a single chemical substance (allotropes). For instance, oxygen exists as both diatomic oxygen (O) and ozone (O). The majority of elements are classified as metals.
Chemical substance identity of benzene, until the correct structure was described by Friedrich August Kekulé. Likewise, the idea of stereoisomerism – that atoms have rigid three-dimensional structure and can thus form isomers that differ only in their three-dimensional arrangement – was another crucial step in understanding the concept of distinct chemical substances. For example, tartaric acid has three distinct isomers, a pair of diastereomers with one diastereomer forming two enantiomers. An element is a chemical substance made up of a particular kind of atom and hence cannot be broken down or transformed by a chemical reaction into a different element, though it