Antibiotic resistance in gonorrhea Antibiotic resistance in gonorrhea The Gonorrhea bacterium Neisseria gonorrhoeae has developed antibiotic resistance to many antibiotics. The bacteria was first identified in 1879, although some Biblical scholars believe that references to the disease can be found as early as Parshat Metzora of the Old Testament. In the 1940s effective treatment with penicillin became available, but by the 1970s resistant strains predominated. Resistance to penicillin has developed through two mechanisms: chromasomally mediated resistance (CMRNG) and penicillinase-mediated resistance (PPNG). CMRNG involves step wise mutation of penA, which codes for the penicillin-binding protein (PBP-2); mtr, which encodes an efflux pump that removes penicillin
Who I Was Born to Be to Be" was composed by Johan Fransson, Tim Larsson, and Tobias Lundgren. Among her most notable performances of "Who I Was Born to Be", Boyle's first live performance of this song was on 7 December 2009 in London before an audience for the taping of her television special "". "Who I Was Born to Be" was used as the theme song for the anime "Welcome to the Space Show" which was released in 2010. Boyle performed the song on The Oprah Winfrey Show in Chicago on 19 January 2010. On 10 July 2011 she performed it in front of a