Dialysis blocks the passage of larger substances (for example, red blood cells, large proteins). This replicates the filtering process that takes place in the kidneys when the blood enters the kidneys and the larger substances are separated from the smaller ones in the glomerulus. The two main types of dialysis, hemodialysis and peritoneal dialysis, remove wastes and excess water from the blood in different ways. Hemodialysis removes wastes and water by circulating blood outside the body through an external filter, called a dialyzer, that contains a semipermeable membrane. The blood flows in one direction and the dialysate flows in the opposite.
Water organ in the gardens at Heilbronn, Württemberg, and parts of one at the Wilhelmshöhe gardens in Kassel. The brothers Francini constructed waterworks and organs at Saint Germain-en-Laye and Versailles, which reached new heights of splendour and extravagance. By the end of the 17th century, however, interest in water organs had waned. As their upkeep was costly they were left to decay and were soon forgotten; by 1920 not one survived (the so-called water organ at Hellbrunn Castle, Salzburg, is a pneumatic organ driven by hydraulically operated bellows). Their mechanism was subsequently misunderstood until the Dutch engineer Van Dijk pointed out in