Pituitary adenoma a constitutional duplication of a chromosome Xq26.3 including "GPR101", or mosaicism for the duplication (present in a minority of cells) in the case of isolated male patients. X-LAG causes about 10% of cases of pituitary gigantism. The pituitary gland or hypophysis is often referred to as the "master gland" of the human body. Part of the hypothalamic-pituitary axis, it controls most of the body's endocrine functions via the secretion of various hormones into the circulatory system. The pituitary gland is located below the brain in a depression (fossa) of the sphenoid bone known as the sella turcica. Although anatomically and
Pituitary gland correlation between pituitary gland volume and Social Anxiety subscale scores was identified which provided a basis for exploring mediation. Again controlling for age, sex, and BMI, DHEA and DHEA-S have been found to be predictive of larger pituitary gland volume, which was also associated with increased ratings of social anxiety. This research provides evidence that pituitary gland volume mediates the link between higher DHEA(S) levels (associated with relatively early adrenarche) and traits associated with social anxiety. Children who experience early adrenarcheal development tend to have larger pituitary gland volume compared to children with later adrenarcheal development. The Greek physician Galen