KRT83 KRT83 Keratin 83, also known as KRT83, is a protein which humans is encoded by the "KRT83" gene. The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1 (KRT81), KRTHB3 (KRT83, this protein), and KRTHB6 (KRT86), is highly related. The other less-related subfamily includes KRTHB2
Human hair color can be found spread around most of Europe. Studies in 2012 showed that naturally blond hair of Melanesians is caused by a recessive mutation in tyrosinase-related protein 1 (TYRP1). In the Solomon Islands, 26% of the population carry the gene; however, it is absent outside of Oceania. Black hair is the darkest hair color. It has large amounts of eumelanin and is more dense than other hair colors. Auburn hair ranges along a spectrum of light to dark red-brown shades. The chemicals which cause auburn hair are eumelanin (brown) and pheomelanin (red), with a higher proportion of red-causing pheomelanin than