Estradiol for tissue of the reproductive organs, supporting the lining of the vagina, the cervical glands, the endometrium, and the lining of the fallopian tubes. It enhances growth of the myometrium. Estradiol appears necessary to maintain oocytes in the ovary. During the menstrual cycle, estradiol produced by the growing follicles triggers, via a positive feedback system, the hypothalamic-pituitary events that lead to the luteinizing hormone surge, inducing ovulation. In the luteal phase, estradiol, in conjunction with progesterone, prepares the endometrium for implantation. During pregnancy, estradiol increases due to placental production. The effect of estradiol, together with estrone and estriol, in pregnancy
Menstrual synchrony synchrony. Setchella, Kendala, and Tyniec investigated whether menstrual synchrony occurred in a semi-free-ranging population of mandrills of 10-group years. They reported that mandrills do not synchronize their menstrual cycles and concluded that cycle synchrony does not occur in non-human primates. Oestrus synchrony has been reported of female lions living under natural conditions in the wild. Menstrual synchrony Menstrual synchrony, also called the McClintock effect, is an alleged process whereby women who begin living together in close proximity experience their menstrual cycle onsets (the onset of menstruation or menses) becoming more synchronized together in time than when previously living apart. "For