Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian (emperor) "The Hard Hours". He is referenced in Evelyn Waugh's "Helena": "Do you know what has happened to the Immortal Valerian?...They have him on show in Persia, stuffed." Valerian (emperor) Valerian (; ; 193/195/200260 or 264), also known as Valerian the Elder, was Roman Emperor from 22 October 253 AD to spring 260 AD. He was taken captive by the Persian Emperor, Shapur I, after the Battle of Edessa, becoming the first Roman emperor to be captured as a prisoner of war, causing shock and instability throughout the empire. Unlike many of the would-be emperors and rebels who vied for imperial