White blood cell normal when it is part of healthy immune responses, which happen frequently. It is occasionally abnormal, when it is neoplastic or autoimmune in origin. A decrease below the lower limit is called leukopenia. This indicates a weakened immune system. The name "white blood cell" derives from the physical appearance of a blood sample after centrifugation. White cells are found in the "buffy" "coat", a thin, typically white layer of nucleated cells between the sedimented red blood cells and the blood plasma. The scientific term "leukocyte" directly reflects its description. It is derived from the Greek roots "leuk-" meaning "white" and
Neonatal red cell transfusion Neonatal red cell transfusion Neonates are defined as babies up to 28 days after birth. Most extremely preterm babies (less than 28 weeks) require at least one red cell transfusion, this is partly due to the amount of blood removed with blood samples compared to the baby's total blood volume (iatrogenic anemia) and partly due to anemia of prematurity. Most transfusions are given as small volume top-up transfusions to increase the baby's hemoglobin above a certain pre-defined level, or because the baby is unwell due to the anemia. Possible side-effects of anemia in babies can be poor growth, lethargy and