Causes of transsexuality Docter and others, but opposed by Charles Allen Moser, Larry Nuttbrock, Julia Serano, and the World Professional Association for Transgender Health.<section end="factors" /> A 2008 study compared 112 male-to-female transsexuals (both androphilic and gynephilic), mostly already undergoing hormone treatment, with 258 cisgender male controls. Male-to-female transsexuals were more likely than cisgender males to have a longer version of a receptor gene (longer repetitions of the gene) for the sex hormone androgen or testosterone, which reduced its effectiveness at binding testosterone. The androgen receptor (NR3C4) is activated by the binding of testosterone or dihydrotestosterone, where it plays a critical role in
Sexual Preference (book) that while Bell "et al."′s suggestion that biological factors have a stronger influence on exclusive homosexuality than they have on bisexuality may seem plausible, it has not been directly tested and appears to conflict with available evidence, such as that concerning prenatal hormone exposure. The psychologist Bruce Rind credited Bell "et al." with disproving psychoanalytic theories about the development of homosexuality, along with the idea that childhood seduction causes homosexuality. The psychologist Mark Yarhouse wrote that while "Sexual Preference" is cited by proponents of a biological explanation, it relies on retrospective memory recall, which can be unreliable. The psychologist J.