Cerebrovascular disease capillary bed separates arteries from veins, which protects the veins from the higher blood pressures that occur in arteries. In arteriovenous malformations, arteries are directly connected to veins, which increases the risk of venous rupture and hemorrhage. Arteriovenous malformations in the brain have a 2–4% chance of rupture each year. However, many arteriovenous malformations go unnoticed and are asymptomatic throughout a person's lifetime. A germinal matrix hemorrhage is bleeding into the brain of premature infants caused by the rupture of fragile blood vessels within the germinal matrix of premature babies. The germinal matrix is a highly vascularized area within an
Great arteries birth. Great arteries The great arteries are the primary arteries that carry blood away from the heart, which include: The great arteries originate from the aortic arches during embryonic development. The aortic arches start as five pairs of symmetrical vessels connecting the heart with the dorsal aorta but then undergo a significant remodelling, in which some of these vessels regress (aortic arches 1 and 2), the 3rd pair of arches contribute to form the common carotids, the right 4th will contribute to the base and central part of the right subclavian artery, while the left 4th will form the central