Rimantadine antagonistic properties and is used as an antiparkinsonic drug (i.e., in the treatment of Parkinson's disease). However, in general, neither rimantadine nor amantadine is a preferred agent for this therapy and would be reserved for cases of the disease that are less responsive to front-line treatments. Taking paracetamol (acetaminophen, Tylenol) or acetylsalicylic acid (aspirin) while taking rimantadine is known to reduce the body's uptake of rimantadine by approximately 12%. Cimetidine also affects the body's uptake of rimantadine. Rimantadine can produce gastrointestinal and central nervous system adverse effects. Approximately 6% of patients (compared to 4% of patients taking a placebo) reported
Acid Tests Acid Tests The Acid Tests were a series of parties held by author Ken Kesey primarily in the San Francisco Bay Area during the mid-1960s, centered entirely on the use of, and advocacy of, the psychedelic drug LSD, also known as "acid". LSD-25 was not made illegal in California until October 6, 1966. The name "Acid Test" was coined by Kesey, after the term "acid test" used by gold miners in the 1850s. He began throwing parties at his farm at La Honda, California. The Merry Pranksters were central to organizing the Acid Tests, including Pranksters such as Lee Quarnstrom