Allergic response produce histamines. These histamines will act on different areas of the body (eyes, throat, nose, gastrointestinal tract, skin or lungs) to produce symptoms of an allergic reaction. The allergic response is not limited to a certain amount of exposure. If the body is exposed to the allergen multiple times the immune system will react every time the allergen is present. The reason why people get allergies is not known. The allergens are not passed down through generations. It is believed if parents have allergies the child is more likely to be allergic to the same allergens. Some common symptoms include
Substance dependence the "Diagnostic and Statistical Manual of Mental Disorders" ("DSM-IV"), substance dependence is redefined as a drug addiction, and can be diagnosed without the occurrence of a withdrawal syndrome. It is now described accordingly: "When an individual persists in use of alcohol or other drugs despite problems related to use of the substance, substance dependence may be diagnosed. Compulsive and repetitive use may result in tolerance to the effect of the drug and withdrawal symptoms when use is reduced or stopped. This, along with Substance Abuse are considered Substance Use Disorders." Withdrawal is the body's reaction to abstaining from a substance