Hypothalamic–pituitary–gonadal axis in which the hypothalamus and pituitary direct neuroendocrine function. The hypothalamus is located in the brain and secretes GnRH. GnRH travels down the anterior portion of the pituitary via the hypophyseal portal system and binds to receptors on the secretory cells of the adenohypophysis. In response to GnRH stimulation these cells produce LH and FSH, which travel into the blood stream. These two hormones play an important role in communicating to the gonads. In females FSH and LH act primarily to activate the ovaries to produce estrogen and inhibin and to regulate the menstrual cycle and ovarian cycle. Estrogen forms
Price controls larger incomes policy package also employing wage controls and other regulatory elements. Although price controls are sometimes used by governments, economists usually agree that price controls don't accomplish what they are intended to do and are generally to be avoided. For example, nearly three-quarters of economists surveyed disagreed with the statement, "Wage-price controls are a useful policy option in the control of inflation." The Roman Emperor Diocletian tried to set maximum prices for all commodities in the late 3rd century AD but with little success. In early 14th century, the Delhi Sultanate ruler Alauddin Khalji instituted several market reforms, which