Hypertensive kidney disease this situation, the kidney supplied blood by the narrowed renal artery suffers from inadequate blood flow, which in turn causes the size of the kidneys to decrease. Other consequences include arterial stiffening, which involves a gradual breakdown of elastic fibers and intima (the innermost layer of a blood vessel) thickening. An alternative mechanism of hypertensive nephropathy is prolonged glomerular hypertension and hence glomerular hyperfiltration. These can occur simultaneously but not necessarily. The idea is that hypertension results in sclerosis of the glomeruli which ultimately means reduced kidney function. As a compensatory mechanism, the unaffected nephrons (specifically, the preglomerular arterioles) vasodilate
Posterior spinal artery column as well as the peripheral part of the anterior and central column. Disruption of blood supply to this particular artery in the medulla would result in a number of sensory deficits. If occlusion occurs above the level of sensory decussation, it would affect the proprioception, vibration, and two-point discrimination of the contralateral side of the body. When occurs below the level of sensory decussation, however, it would cause the effect on the ipsilateral side instead. Particularly at the upper cervical spinal cord where the posterior spinal artery supplies some parts of the ventral column, lesion might extend to the