Heart rate persons with coronary artery disease. The heart rate is rhythmically generated by the sinoatrial node. It is also influenced by central factors through sympathetic and parasympathetic nerves. Nervous influence over the heartrate is centralized within the two paired cardiovascular centres of the medulla oblongata. The cardioaccelerator regions stimulate activity via sympathetic stimulation of the cardioaccelerator nerves, and the cardioinhibitory centers decrease heart activity via parasympathetic stimulation as one component of the vagus nerve. During rest, both centers provide slight stimulation to the heart, contributing to autonomic tone. This is a similar concept to tone in skeletal muscles. Normally, vagal stimulation
Heart rate number of different metrics are used to describe heart rate. Normal pulse rates at rest, in beats per minute (BPM): The basal or resting heart rate (HR) is defined as the heart rate when a person is awake, in a neutrally temperate environment, and has not been subject to any recent exertion or stimulation, such as stress or surprise. A large body of evidence indicates that the normal range is 60-100 beats per minute. This resting heart rate is often correlated with mortality. For example, all-cause mortality is increased by 1.22 (hazard ratio) when heart rate exceeds 90 beats per