Bachmann's bundle that area. The normal cardiac rhythm originates in the sinoatrial node, which is located in the right atrium near the superior vena cava. From there, the electrical activation spreads throughout the right atrium. There are at least four different locations where the activation can pass to the left atrium. Apart from Bachmann's bundle these are the anterior interatrial septum, posterior interatrial septum, and the coronary sinus. Because it originates close to the sinoatrial node and consists of long parallel fibers, Bachmann's bundle is, during sinus rhythm, the first of these connections to activate the left atrium. Bachmann's bundle In the
Lymph node stromal cell travel from the bone marrow or high endothelial venules of the thymus where they develop as lymphoblasts, to lymph nodes, where they mature. The primary role of lymph node stromal cells is structural. They form a scaffold for hematopoietic cells and assist their movement along it. The molecular signaling systems (chemokines) that distribute lymphocytes to appropriate localities within the lymph node (T and B cell segregation) are also created by lymph node stromal cells. Lymphocytes have receptors for such chemokines. For example, Naive T cells express the CCR7 receptor for the chemokine CCL21. and B cells exhibit CXCR5 receptors for