Conserved non-coding sequence degenerate sequences with no biological function. An example of a pseudogene is the gene for L-gulonolactone oxidase, a liver enzyme necessary for biosynthesis of L-ascorbic acid (vitamin C) in most birds and mammals, but which is mutated in the haplorrhini suborder of primates, including humans which require ascorbic acid or ascorbate from food. The remains of this non-functional gene with many mutations is still present in the genomes of guinea pigs and humans. Ultraconserved regions (UCRs) are regions over 200 bp in length with 100% identity across species. These unique sequences are mostly found in noncoding regions. It is still
Vitamin C had proven this, but published the result without giving Szent-Györgyi credit for it. This led to a bitter dispute over priority. In 1933, Walter Norman Haworth chemically identified the vitamin as -hexuronic acid, proving this by synthesis in 1933. Haworth and Szent-Györgyi proposed that L-hexuronic acid be named a-scorbic acid, and chemically -ascorbic acid, in honor of its activity against scurvy. The term's etymology is from Latin, "a-" meaning away, or off from, while -scorbic is from Medieval Latin "scorbuticus" (pertaining to scurvy), cognate with Old Norse "skyrbjugr", French "scorbut", Dutch "scheurbuik" and Low German "scharbock". Partly for this discovery,