Development of the digestive system Development of the digestive system The development of the digestive system concerns the epithelium of the digestive system and the parenchyma of its derivatives, which originate from the endoderm. Connective tissue, muscular components, and peritoneal components originate in the mesoderm. Different regions of the gut tube such as the esophagus, stomach, duodenum, etc. are specified by a retinoic acid gradient that causes transcription factors unique to each region to be expressed. Differentiation of the gut and its derivatives depends upon reciprocal interactions between the gut endoderm and its surrounding mesoderm. Hox genes in the mesoderm are induced by a Hedgehog
Canadian Digestive Health Foundation Canadian Digestive Health Foundation The Canadian Digestive Health Foundation ("French:" Fondation Canadienne de la Santé Digestive) or CDHF, is a registered Canadian charity. The organization was founded in 1993 as the Canadian Digestive Disease Foundation and renamed the Canadian Digestive Health Foundation in 2001. The objectives of the Foundation are to educate the general public about digestive disease and nutrition, and to advance the science of gastroenterology by funding medical research. In February 2001, it was officially endorsed as the Foundation for the Canadian Association of Gastroenterology. Since then it has raised and invested more than $1 million to fund