Sinoatrial node rate, and increasing heart rate. An increase in heart rate is known as positive chronotropy. The parasympathetic nerves supplying the SA node (in particular the Vagus nerves) originate in the brain. These nerves release a neurotransmitter called acetylcholine (ACh). ACh binds to a receptor called an M2 muscarinic receptor, located on the SA node membrane. Activation of this M2 receptor, then activates a protein called a G-protein (in particular G protein, i for inhibitory). Activation of this G-protein, blocks the cAMP pathway, reducing its effects, therefore inhibiting sympathetic activity and slowing action potential production. As well as this, the G-protein
Lunar node a location by averaging the height of the lowest tide recorded at that location each day during a 19-year recording period, known as the National Tidal Datum Epoch. The 19-year recording period is the nearest full-year count to the 18.6-year cycle of the lunar nodes. Lunar node A lunar node is either of the two orbital nodes of the Moon, that is, the two points at which the orbit of the Moon intersects the ecliptic. The "ascending" (or "north") node is where the Moon moves into the northern ecliptic hemisphere, while the "descending" (or "south") node is where the Moon