Man labioscrotal folds into the scrotum. Another significant hormone in sexual differentiation is the anti-Müllerian hormone, which inhibits development of the Müllerian ducts. In general, men suffer from many of the same illnesses as women. In comparison to women, men suffer from slightly more illnesses. Male life expectancy is slightly lower than female life expectancy, although the difference has narrowed in recent years. For males during puberty, testosterone, along with gonadotropins released by the pituitary gland, stimulates spermatogenesis, along with the full sexual distinction of a human male from a human female, while women are acted upon by estrogens and progesterone
Anti-Müllerian hormone testis suppresses Müllerian development only on its own side. In humans, this action takes place during the first 8 weeks of gestation. If no hormone is produced from the gonads, the Müllerian ducts automatically develop, while the Wolffian ducts, which are responsible for male reproductive parts, automatically die. Amounts of AMH that are measurable in the blood vary by age and sex. AMH works by interacting with specific receptors on the surfaces of the cells of target tissues (anti-Müllerian hormone receptors). The best-known and most specific effect, mediated through the AMH type II receptors, includes programmed cell death (apoptosis) of