Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
A Is for Acid A Is for Acid A Is for Acid is a 2002 British television film based on the life of the serial killer John George Haigh, known as the Acid Bath Murderer, because he dissolved the bodies of six people in sulphuric acid. Haigh, hanged in 1949 for his crimes, had wrongly believed that murder could not be proven without the presence of a body. Starring Martin Clunes in the lead role, the film was shot in Scarborough, chosen because its appearance was believed similar to that of London when Haigh lived there during the 1940s. The film was produced by