Protein signalling in heart development Protein signalling in heart development The heart is the first functional organ in a vertebrate embryo. There are 5 stages to heart development. Specification of cardiac precursor cells: The lateral plate mesoderm delaminates to form two layers: the dorsal somatic (parietal) mesoderm and the ventral splanchnic (visceral) mesoderm. The heart precursor cells come from the two regions of the splanchnic mesoderm called the cardiogenic mesoderm. These cells can differentiate into endocardium which lines the heart chamber and valves and the myocardium which forms the musculature of the ventricles and the atria. The heart cells are specified in anterior mesoderm by
How many angels can dance on the head of a pin? about how many could perch at the same time on the head of a pin"". Dorothy L. Sayers argued that the question was "simply a debating exercise" and that the answer "usually adjudged correct" was stated as, "Angels are pure intelligences, not material, but limited, so that they have location in space, but not extension." Sayers compares the question to that of how many people's thoughts can be concentrated upon a particular pin at the same time. She concludes that infinitely many angels can be located on the head of a pin, since they do not occupy any space there: