Parasympathetic nervous system act in a complementary way increasing or slowing the heart rate. In this context, the vagus nerve acts on sinoatrial node slowing its conduction thus actively modulating vagal tone accordingly. This modulation is mediated by the neurotransmitter acetylcholine and downstream changes to ionic currents and calcium of heart cells. The vagus nerve plays a crucial role in heart rate regulation by modulating the response of sinoatrial node, vagal tone can be quantified by investigating heart rate modulation induced by vagal tone changes. As a general consideration, increased vagal tone (and thus vagal action) is associated with a diminished and more
Node deletion Node deletion Node deletion is the procedure of removing a node from a network, where the node is either chosen randomly or directly. Node deletion is used to test the robustness and the attack tolerance of networks. Understanding how a network changes in response to node deletion is critical in many empirical networks. Application varies across many fields, including the breakdown of the World Wide Web via router removal, elimination of epidemics or fighting against criminal organizations. Removing a node or multiple nodes randomly from a network means that the elimination of a set of nodes happens with a certain