John Jacob Abel to successfully isolate the neutral base of epinephrine by adding ammonium to highly concentrated extract, a method Abel himself tried but failed due to the use of low concentration of extract. After Takamine's success, Abel himself remarked, with great candor, "The efforts of years on my part in this once mysterious field of suprarenal, medullary biochemistry, marred by blunders as they were, eventuated, then, in the isolation of the hormone not in the form of the free base but in that of its monobenzoyl derivative." Together with L.G. Rowntree and B.B. Turner, Abel devised what they called a "vividiffusion" apparatus,
John Jacob Abel pathology, and Johannes Wislicenus in organic and inorganic chemistry. All of this work was done in Leipzig until 1886, until Abel moved on to Strassburg, where he again worked in various fields: internal medicine with Adolph Kussmaul, and Friedrich Daniel von Recklinghausen in infectious disease and pathology. Eventually, Abel moved back to Strassburg where he worked more with Oswald Schmiedeberg among others. Schmeidberg, however, sparked his interest in pharmacological research. Lastly, he worked in a biochemical laboratory in Berne, where he met one Arthur Robertson Cushny, who eventually worked with him at Michigan. Finishing his time in Europe, Abel returned