Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian Kuybyshev (ship) Valerian Kuybyshev (ship) The Valerian Kuybyshev () is a "Valerian Kuybyshev"-class (92-016, OL400) Soviet/Russian river cruise ship, cruising in the Volga – Neva basin. The ship was built by Slovenské Lodenice at their shipyard in Komárno, Czechoslovakia and entered service in 1976. She was named after prominent Soviet politician Valerian Kuybyshev. At 3,950 tonnes, "Valerian Kuybyshev" is one of the world's biggest river cruise ships. Her sister ships are "Feliks Dzerzhinskiy", "Mikhail Frunze", "Fyodor Shalyapin", "Sergey Kuchkin", "Mstislav Rostropovich", "Aleksandr Suvorov", "Semyon Budyonnyy" and "Georgiy Zhukov". "Valerian Kuybyshev" is currently operated by "Vodohod", the biggest Russian river cruise line. She