Scar healing which heals with a scar. The myofibroblasts make up a high proportion of the fibroblasts proliferating in the postembryonic wound at the onset of healing. In the rat model, for instance, myofibroblasts can constitute up to 70% of the fibroblasts, and is responsible for fibrosis on tissue. Generally, the myofibroblasts disappear from the wound within 30 days, but can stay around in pathological cases in hypertrophy, such as keloids. Myofibroblasts have plasticity and in mice can be transformed into fat cells, instead of scar tissue, via the regeneration of hair follicles. Early and effective treatment of acne scarring can
Scar (The Lion King) artist Jorgen Klubien. According to the directors, "[a] patronizing quality" was vital to Scar's role in the film. Minkoff told the "Los Angeles Times", "When Scar puts the guilt trip on Simba, that's an intense idea ... probably something that is "not" typical of the other Disney pictures, in terms of what the villain does." Additionally, Scar serves as a departure from previous Disney villains because they "came off at least as buffoonish as they were sinister". Because Scar is the film's main antagonist, supervising animator Andreas Deja believed that "villains work really well when they're subtle", explaining, "to see