Pure red cell aplasia to respond to treatments with rituximab and tacrolimus. Pure red cell aplasia Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of anemia affecting the precursors to red blood cells but not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. There are multiple etiologies that can cause PRCA. The condition has been first described by Paul Kaznelson in 1922. Signs and symptoms may include: Causes of PRCA include: PRCA is considered an autoimmune disease as it will respond to immunosuppressant treatment such as cyclosporin in many patients, though this approach is
Blood Red Horse Blood Red Horse Blood Red Horse is a 2004 young adult historical novel by author K M Grant. The book was published in 2004 by Puffin Books and in the US in 2005 by Walker Children's. "Blood Red Horse" is the first novel in the De Granville Trilogy and was followed by the books "Green Jasper" and "Blaze of Silver". In 2006 the audiobook version of "Blood Red Horse" won an AudioFile Earphones Award and in 2007 was one of YALSA's recommended audiobooks for 2007. "Blood Red Horse" follows Will and Ellie, two young teens growing up during the time