Origin of the domestic dog as the Tibetan people. A population genetic analysis then showed a significant convergence between humans and dogs in Tibet. Like the Tibetan people, Tibetan mastiffs appear to have derived these benefits partially from the EPAS1 gene, acquired through introgression. In 2015, a study found that when dogs and their owners interact, extended eye contact (mutual gaze) increases oxytocin levels in both the dog and its owner. As oxytocin is known for its role in maternal bonding, it is considered likely that this effect has supported the coevolution of human-dog bonding. One observer has stated, "The dog could have arisen only
Origin of the domestic dog agriculture, which was approximately 10,000 years before present (YBP). The earlier association of dogs with humans may have allowed dogs to have a profound influence on the course of early human history and the development of civilization. However, the timing, geographic locations, and ecological conditions that led to dog domestication are not agreed. Genetic studies indicate that the gray wolf is the closest living relative of the dog, with no evidence of any other canine species having contributed. Attempting to reconstruct the dog's lineage through the phylogenetic analysis of DNA sequences from modern dogs and wolves has given conflicting results