Diuresis used to increase urine output and decrease extracellular fluid volume. Substances in the circulation can also increase the amount of circulating fluid by increasing the osmolarity of the blood. This has the effect of pulling water from the interstitial space, making more water available in the blood and causing the kidney to compensate by removing it as urine. In hypotension, often colloids are used intravenously to increase circulating volume in themselves, but as they exert a certain amount of osmotic pressure, water is therefore also moved, further increasing circulating volume. As blood pressure increases, the kidney removes the excess fluid
Organ procurement Organ procurement Organ procurement (previously called organ harvesting) is a surgical procedure that removes organs or tissues for reuse, typically for organ transplantation. It is heavily regulated by United Network for Organ Sharing (UNOS) to prevent unethical allocation of organs. There are over 110,000 patients on the national waiting list for organ transplantation and in 2016, only about 33,000 organ transplants were performed. Due to the lack of organ availability, about 20 patients die each day on the waiting list for organs. Organ transplantation and allocation is mired in ethical debate because of this limited availability of organs for transplant.