Diuresis used to increase urine output and decrease extracellular fluid volume. Substances in the circulation can also increase the amount of circulating fluid by increasing the osmolarity of the blood. This has the effect of pulling water from the interstitial space, making more water available in the blood and causing the kidney to compensate by removing it as urine. In hypotension, often colloids are used intravenously to increase circulating volume in themselves, but as they exert a certain amount of osmotic pressure, water is therefore also moved, further increasing circulating volume. As blood pressure increases, the kidney removes the excess fluid
Organ printing are some organ-specific structural elements that must be addressed for successful creation of a transplantable printed organ. The transfer of nutrients and oxygen to cells throughout a printed organ is essential for its function. In very small or thin tissues of less than a millimeter in thickness, cells can receive nutrients through diffusion. However, larger organs require the transportation of nutrients to cells deeper inside the tissue, which requires that the tissue be vascularized, and thus able to receive blood for the exchange of cargo like oxygen and cell wastes. Early organ printing techniques created solid tissues that were unable