Myringoplasty perforation and a small part should also extend over the posterior canal wall. The tympanomeatal flap is then replaced. The temporal fascia is harvested. An incision is made to raise medial meatal skin with tympanic membrane epithelium. The graft is placed on the outer surface of the tympanic membrane and a slit is made to tuck it under the handle of malleus. The ear is packed with gelfoam and antibiotics, and the incision is closed. Finally mastoid dressing is performed. Myringoplasty Myringoplasty is the closure of the perforation of pars tensa of the tympanic membrane. When myringoplasty is combined with
Membrane stabilizing effect Membrane stabilizing effect Membrane stabilizing effects involve the inhibition or total abolishing of action potentials from being propagated across the membrane. This phenomenon is common in nerve tissues as they are the carrier of impulses from the periphery to the central nervous system. Membrane stabilization is the method through which local anesthetics work. They block the propagation of action potentials across nerve cells, thereby producing a nerve block. Some beta-blockers also possess what is referred to as membrane stabilizing activity (MSA). This effect is similar to the membrane stabilizing activity of sodium channel blockers that represent Class I antiarrhythmics. MSA