Ozone layer upper-atmosphere ozone-depletion rate slowed down significantly during the previous decade. Some breakdown can be expected to continue because of ODSs used by nations which have not banned them, and because of gases which are already in the stratosphere. Some ODSs, including CFCs, have very long atmospheric lifetimes, ranging from 50 to over 100 years. It has been estimated that the ozone layer will recover to 1980 levels near the middle of the 21st century. A gradual trend toward "healing" was reported in 2016. Compounds containing C–H bonds (such as hydrochlorofluorocarbons, or HCFCs) have been designed to replace CFCs in certain
Ozone depletion CFCs means that nitrous oxide (), which is not covered by the Montreal Protocol, has become the most highly emitted ozone-depleting substance and is expected to remain so throughout the 21st century. A 2005 IPCC review of ozone observations and model calculations concluded that the global amount of ozone has now approximately stabilized. Although considerable variability is expected from year to year, including in polar regions where depletion is largest, the ozone layer is expected to begin to recover in coming decades due to declining ozone-depleting substance concentrations, assuming full compliance with the Montreal Protocol. The Antarctic ozone hole is