Vitamin C megadosage Based on that study, the American Burn Association (ABA) considers high-dose ascorbic acid an option to be considered for adjuvant therapy in addition to the more accepted standard treatments. Atrial fibrillation (AF) is a common cardiac rhythm disturbance and it is associated with oxidative stress. Four meta-analyses have concluded that there is strong evidence that 1-2 g/day of vitamin C before and after cardiac operations can decrease the risk of post-operative AF. However, five randomized studies did not find benefit in the USA, so that the benefit was restricted to less wealthy countries. Exercise-induced bronchoconstriction (EIB) indicates acute narrowing of
Vitamin B12 leading to vitamin B deficiency. Protein-bound vitamin B must be released from the proteins by the action of digestive proteases in both the stomach and small intestine. Gastric acid releases the vitamin from food particles; therefore antacid and acid-blocking medications (especially proton-pump inhibitors) may inhibit absorption of B. B taken in a low-solubility, non-chewable supplement pill form may bypass the mouth and stomach and not mix with gastric acids, but acids are not necessary for the absorption of free B not bound to protein; acid is necessary only to recover naturally-occurring vitamin B from foods. R-protein (also known as haptocorrin