Max Perutz the onset of Huntington disease is related to the number of glutamine repeats as they bind to form what he called a polar zipper. During the early 1950s, while Watson and Crick were determining the structure of deoxyribonucleic acid (DNA), they made use of unpublished X-ray diffraction images taken by Rosalind Franklin, shown at meetings and shared with them by Maurice Wilkins, and of Franklin's preliminary account of her detailed analysis of the X-ray images included in an unpublished 1952 progress report for the King's College laboratory of Sir John Randall. Randall and others eventually criticised the manner in which
Photo 51 her own data, had Watson and Crick not obtained Gosling's image, is a hotly debated topic, made more controversial by the negative caricature of Franklin presented in the early chapters of Watson's history of the research on DNA structure, "The Double Helix". Watson admitted his distortion of Franklin in his book, noting in the epilogue: "Since my initial impressions about [Franklin], both scientific and personal (as recorded in the early pages of this book) were often wrong, I want to say something here about her achievements." Photo 51 Photograph 51 is the nickname given to an X-ray diffraction image of