Hypertensive kidney disease this situation, the kidney supplied blood by the narrowed renal artery suffers from inadequate blood flow, which in turn causes the size of the kidneys to decrease. Other consequences include arterial stiffening, which involves a gradual breakdown of elastic fibers and intima (the innermost layer of a blood vessel) thickening. An alternative mechanism of hypertensive nephropathy is prolonged glomerular hypertension and hence glomerular hyperfiltration. These can occur simultaneously but not necessarily. The idea is that hypertension results in sclerosis of the glomeruli which ultimately means reduced kidney function. As a compensatory mechanism, the unaffected nephrons (specifically, the preglomerular arterioles) vasodilate
End artery liver, kidneys, spleen and intestines; they may also exist in the heart. IMPORTANCE OF END ARTERIES :- Occlusion of an end-artery causes serious nutritional disturbances resulting in death of the tissue supplied by it. For example, occlusion of central artery of retina results in blindness. The results are severe because the blood flow to that region is completely stopped since there is no collateral circulation. End artery An end artery (or terminal artery) is an artery that is the only supply of oxygenated blood to a portion of tissue. Arteries which do not anastomose with their neighbors are called end