Valerian (herb) particular binding site. Hydrophilic extractions of the herb commonly sold over the counter, however, probably do not contain significant amounts of isovaltrate. Valerenic acid in valerian stimulates serotonin receptors as a partial agonist, including 5-HT which is implicated in the sleep-wake cycle. The chief constituent of valerian is a yellowish-green to brownish-yellow oil present in the dried root, varying in content from 0.5 to 2.0%. This variation in quantity may be determined by location; a dry, stony soil yields a root richer in oil than moist, fertile soil. The volatile oils that form the active ingredient are pungent, somewhat reminiscent
I. Valerian I. Valerian I. Valerian (born Valeriu Ionescu; August 1, 1895 – November 21, 1980) was a Romanian writer and journalist. Born in Ivești, Galați County, the son of Fotache, a worker and clerk active in Ivești and Tecuci, and his wife Amalia, he spent his childhood in Tecuci. There he attended school at the primary and gymnasium levels before going to Vasile Alecsandri High School in Galați from 1907 to 1915. In 1917, during World War I, he graduated from the Military Reserve Officers' School in Bucharest, going on to participate in the Battle of Mărăști as part of the