Tendon induce endothelial cell proliferation and migration, and VEGF mRNA has been shown to be expressed at the site of tendon injuries along with collagen I mRNA. Bone morphogenetic proteins (BMPs) are a subgroup of TGF-β superfamily that can induce bone and cartilage formation as well as tissue differentiation, and BMP-12 specifically has been shown to influence formation and differentiation of tendon tissue and to promote fibrogenesis. In animal models, extensive studies have been conducted to investigate the effects of mechanical strain in the form of activity level on tendon injury and healing. While stretching can disrupt healing during the initial
Conjoint tendon A weakening of the conjoint tendon can precipitate a direct inguinal hernia. A direct inguinal hernia will protrude through Hesselbach's triangle, whose borders are the rectus abdominis (medially), inferior epigastric artery and vein (superolaterally), and the inguinal ligament (inferiorly). The hernia will lie medial to the inferior epigastric artery. This is in contrast to an indirect inguinal hernia, which will protrude laterally to the inferior epigastric artery and is most commonly due to an embryological defect in the closure of the deep inguinal ring. Conjoint tendon The conjoint tendon (previously known as the inguinal aponeurotic falx) is a structure formed