Valerian (herb) nervous system depression, they should not be used with other depressants, such as ethanol, benzodiazepines, barbiturates, opiates, kava, or antihistamine drugs. Moreover, non-pregnant adult human hepatotoxicity has been associated with short-term use (i.e., a few days to several months) of herbal preparations containing valerian and "Scutellaria" (commonly called skullcap). As an unregulated product, the concentration, contents, and potential contaminants in valerian preparations cannot be easily determined. Because of this uncertainty and the potential for toxicity in the fetus and hepatotoxicity in the mother, valerian use is discouraged during pregnancy. Valerian root is a cat attractant in a way similar to
Valerian and the City of a Thousand Planets production budget of around $180 million, it is both the most expensive non-American and independent film ever made. "Valerian" was released by STXfilms on 21 July 2017 in the United States, and in France on 26 July, by EuropaCorp. It received mixed reviews from critics, who criticized the plot and some of the casting, but praised the visuals. It grossed $225 million worldwide, but due to its high production and advertising costs, it was considered a commercial failure following its release in the United States. In the 28th century, due to cooperation between the Earth's countries (beginning with the ASTP