Protein signalling in heart development Protein signalling in heart development The heart is the first functional organ in a vertebrate embryo. There are 5 stages to heart development. Specification of cardiac precursor cells: The lateral plate mesoderm delaminates to form two layers: the dorsal somatic (parietal) mesoderm and the ventral splanchnic (visceral) mesoderm. The heart precursor cells come from the two regions of the splanchnic mesoderm called the cardiogenic mesoderm. These cells can differentiate into endocardium which lines the heart chamber and valves and the myocardium which forms the musculature of the ventricles and the atria. The heart cells are specified in anterior mesoderm by
The Heart String & How to Pull It 21 March and finishing on 8 April. Pledgers were offered various basic packages that included a physical copy of the album, a digital download of the album, a download of what became the "Chemicals EP", an album-themed T-shirt and an album-themed poster. All of the basic packages included the option to download the album a few days in advance of the physical release. Additionally, there were several special packages that were offered at premium prices. All of the special packages included a digital download of the album. The Heart String & How to Pull It The Heart String & How