Endocrinology of reproduction half of pregnancy, progesterone and prolactin prepare the mammary glands for lactation. Estrogens and progesterone promote mammary epithelial cell proliferation resulting in the formation of the primary and secondary ductal structure. Progesterone induces formation of tertiary side-branches in the mammary glands during puberty and during the luteal phase of the menstrual cycle upon which lobuloalveolar structures form under the influence of prolactin. Prolactin stimulates lactogenesis. hCG appears to be soporific during pregnancy; levels of hCG correlate with sleep changes during pregnancy, and administration of hCG increases sleep in rats likely via neuronal LHCGR. Endocrinology of reproduction Hormonal regulation occurs at
Fern test When high levels of estrogen are present, just before ovulation, the cervical mucus forms fern-like patterns due to crystallization of sodium chloride on mucus fibers. This pattern is known as arborization or 'ferning'. When progesterone is the dominant hormone, as it would be in the second half of a normal cycle, the fern pattern is no longer discernible, and the pattern is completely absent by the 22nd day of a woman's cycle. The disappearance of the fern pattern after the 22nd day suggests ovulation, and its persistence throughout the menstrual cycle suggests an-ovulation (infertility). Fern test Fern test refers to