Max Perutz the onset of Huntington disease is related to the number of glutamine repeats as they bind to form what he called a polar zipper. During the early 1950s, while Watson and Crick were determining the structure of deoxyribonucleic acid (DNA), they made use of unpublished X-ray diffraction images taken by Rosalind Franklin, shown at meetings and shared with them by Maurice Wilkins, and of Franklin's preliminary account of her detailed analysis of the X-ray images included in an unpublished 1952 progress report for the King's College laboratory of Sir John Randall. Randall and others eventually criticised the manner in which
Rudolf Signer from the Thymus of calves, of which he took 15 grams of extraordinarily pure DNA to London. In England he gave it to various scientists, among them Maurice Wilkins, in order to promote research in the field. The analysis of X ray images of these DNA samples in Wilkins' laboratory allowed James Watson and Francis Crick to discover the double-helix structure of DNA. Rests of the DNA which Signer brought to England, survive today in the collection of King's College, London. Over 250 of Signer's scientific writings were published during his lifetime. The Lavoisier Medal was awarded to him for