Allergic inflammation immediate allergic reaction or as a Type I allergic reaction. The reaction is caused by the release of histamine and mast cell granule proteins by a process called degranulation, as well as the production of leukotrienes, prostaglandins and cytokines, by mast cells following the cross-linking of allergen specific IgE molecules bound to mast cell FcεRI receptors. These mediators affect nerve cells causing itching, smooth muscle cells causing contraction (leading to the airway narrowing seen in allergic asthma), goblet cells causing mucus production, and endothelial cells causing vasodilatation and edema. The late phase of a Type 1 reaction (which develops 8–12
The Pollen Room The Pollen Room The Pollen Room (German: "Das Blütenstaubzimmer") is the debut novel by Swiss author Zoë Jenny. Published in 1997, the book was a literary and commercial success in Switzerland and across Europe. The novel was published in Germany by Frankfurter Verlagsanstalt, with an advance of less than 10,000 marks. After publication, the novel reached #2 on Switzerland's best sellers list and won several literary prizes in Austria and Germany. "The Pollen Room" contains some autobiographical elements. In the novel, Jo's parents separate when she is a child, and she lives with her father (a publisher) until she decides