Cerebrovascular disease capillary bed separates arteries from veins, which protects the veins from the higher blood pressures that occur in arteries. In arteriovenous malformations, arteries are directly connected to veins, which increases the risk of venous rupture and hemorrhage. Arteriovenous malformations in the brain have a 2–4% chance of rupture each year. However, many arteriovenous malformations go unnoticed and are asymptomatic throughout a person's lifetime. A germinal matrix hemorrhage is bleeding into the brain of premature infants caused by the rupture of fragile blood vessels within the germinal matrix of premature babies. The germinal matrix is a highly vascularized area within an
Great arteries of the aortic arch. The 5th pair of vessels only form in some cases without any known contribution to the final structure of the great arteries. The right 6th almost completely regresses with only the proximal part contributing to the base of the pulmonary arteries, while the left 6th forms the ductus arteriosus, which disappears after birth. Abnormalities in the development of the great arteries during embryonic development may lead to congenital cardiovascular defects, such as: Some of these defects can be asymptomatic and cause no complications in patients, with others being more severe and require immediate surgery right after