Legionnaires' disease Although the risk of Legionnaires' disease being spread by large-scale water systems cannot be eliminated, it can be greatly reduced by writing and enforcing a highly detailed, systematic water safety plan appropriate for the specific facility involved (office building, hospital, hotel, spa, cruise ship, etc.) Some of the elements that such a plan may include are: An effective water safety plan also covers such matters as training, record-keeping, communication among staff, contingency plans, and management responsibilities. The format and content of the plan may be prescribed by public health laws or regulations. Effective antibiotics include most macrolides, tetracyclines, ketolides, and
Bacterial cold water disease lethargy, inappetence and exopthalmos before death. A presumptive diagnosis can be made based on the history, clinical signs, pattern of mortality and water temperature, especially if there is a history of the disease in the area. The organism can be cultured for definitive diagnosis. Alternatively, histology should show periostitis, osteitis, meningitis and ganglioneuritis. Quaternary ammonium compounds can be added to the water of infected adult fish and fry. Alternatively, the antibiotic oxytetracycline can be given to adults, fry and broodstock. To prevent the disease, it is necessary to ensure water is pathogen-free and that water hardening is completed effectively for