Transgender hormone therapy (male-to-female) medical professional. Inducers of CYP3A4 and other cytochrome P450 enzymes can reduce the effects of MTF HRT. A variety of different sex-hormonal medications are used in feminizing hormone therapy for transgender women. These include estrogens to induce feminization and suppress testosterone levels; antiandrogens such as androgen receptor antagonists, antigonadotropins, GnRH modulators, and 5α-reductase inhibitors to further oppose the effects of androgens like testosterone; and progestogens for various possible though uncertain benefits. Estrogens are the major sex hormones in women, and are responsible for the development and maintenance of feminine secondary sexual characteristics, such as breasts, wide hips, and a feminine
Human male sexuality with a male, and decrease the chance that the female will mate with another male. There are several strategies by which sexual coercion can be achieved. These are harassment, intimidation, and forced copulation (rape). Thornhill and Palmer's "A Natural History of Rape" investigates the evolutionary causes of sexual coercion, particularly of rape, and suggest that such behaviour is a result of sexual selection, rather than Darwinian natural selection. Of ten listed hypotheses, they accepted two reasonable hypotheses: Thornhill and Palmer argue that these two theories are the strongest of the ten for several reasons. For example, both hypothesis argue rape