Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
Acid test (gold) to assess the liquidity of a business. The use of the term "acid test" for experiences with the psychedelic drug LSD was popularised by the Merry Pranksters, and derives from the drug's common name, "acid". Acid test (gold) An acid test is any qualitative chemical or metallurgical assay which uses acid; most commonly, and historically, the use of a strong acid to distinguish gold from base metals. Figuratively, acid test is any definitive test for some attribute, e.g. of a person's character, or of the performance of product. Testing for gold with acid focuses on the fact that gold is