Recreational drug use are caused by an excessive response of the body to allergens, such as the pollen released by grasses and trees. An allergic reaction causes release of histamine by the body. Other uses of antihistamines are to help with normal symptoms of insect stings even if there is no allergic reaction. Their recreational appeal exists mainly due to their anticholinergic properties, that induce anxiolysis and, in some cases such as diphenhydramine, chlorpheniramine, and orphenadrine, a characteristic euphoria at moderate doses. High dosages taken to induce recreational drug effects may lead to overdoses. Antihistamines are also consumed in combination with alcohol, particularly
Is the Is Are substance," following an incident in which their car was pulled over by the police, en route to the Basilica Music Festival. Smith stated that the incident greatly influenced the writing and recording of "Is the Is Are": "What happened to us was really shitty and traumatic, and it wasn’t something I did to get attention — it was the worst possible thing that could have happened at that moment. I knew it was going to take a really good album to save me. That’s what made it so hard to write, and why it took so long. If I didn’t