Man labioscrotal folds into the scrotum. Another significant hormone in sexual differentiation is the anti-Müllerian hormone, which inhibits development of the Müllerian ducts. In general, men suffer from many of the same illnesses as women. In comparison to women, men suffer from slightly more illnesses. Male life expectancy is slightly lower than female life expectancy, although the difference has narrowed in recent years. For males during puberty, testosterone, along with gonadotropins released by the pituitary gland, stimulates spermatogenesis, along with the full sexual distinction of a human male from a human female, while women are acted upon by estrogens and progesterone
Transgender hormone therapy (male-to-female) cases of prostate cancer in transgender women have been reported in the literature. As such, and in accordance with the fact that androgens are responsible for the development of prostate cancer, HRT appears to be highly protective against prostate cancer in transgender women. The risks of hormone-sensitive cancers in transgender women have been reviewed. Estrogens and progestogens can cause prolactinomas, which are prolactin-secreting tumors of the pituitary gland. Milk discharge from the nipples can be a sign of elevated prolactin levels. If a prolactinoma becomes large enough, it can cause visual changes (especially decreased peripheral vision), headaches, depression or other