Hyaline layer of Hopewell-Smith derivative proteins, such as Emdogain, in trying to stimulate reproduction of cementum in periodontal bony defects is based on the presence of enamel matrix-like proteins within the hyaline layer. Hyaline layer of Hopewell-Smith In tooth development, the hyaline layer of Hopewell-Smith is the most peripheral layer of initially unmineralized dentin that forms immediately subjacent to the cementodentinal junction (CDJ). It eventually mineralizes, but not before the rest of the dentin is already mineralized. It is 0.5-0.8 µm thick and contains enamel matrix-like protein as well as the proteins one would expect to find in dentin. It is into this hyaline
Radius of outermost closed isobar Radius of outermost closed isobar The radius of outermost closed isobar (ROCI) is one of the quantities used to determine the size of a tropical cyclone. It is determined by measuring the radii from the center of the storm to its outermost closed isobar in four quadrants, which is then averaged to come up with a scalar value. It generally delimits the outermost extent of a tropical cyclone's wind circulation. Use of this measure has objectively determined that tropical cyclones in the northwest Pacific Ocean are the largest on earth on average, with North Atlantic tropical cyclones roughly half their