Vascular resistance is a fluid layer in which at a distance δ, viscosity η is a function of δ written as η(δ), and these surrounding layers do not meet at the vessel centre in real blood flow. Instead, there is the plugged flow which is hyperviscous because holding high concentration of RBCs. Thurston assembled this layer to the flow resistance to describe blood flow by means of a viscosity η(δ) and thickness δ from the wall layer. The blood resistance law appears as R adapted to blood flow profile : where Blood resistance varies depending on blood viscosity and its plugged flow
Flow focusing seeded in hydrodynamic focussing which has been in existence since 1963, as was developed by flow cytometry scientist. The basic principle consists of a continuous phase fluid (focusing or sheath fluid) flanking or surrounding the dispersed phase (focused or core fluid), so as to give rise to droplet or bubble break-off in the vicinity of an orifice through which both fluids are extruded. The principle may be extended to two or more coaxial fluids; gases and liquids may be combined; and, depending of the geometry of the feed tube and orifices, the flow pattern may be cylindrical or planar. Both