Free fatty acid receptor 1 high abundance. FFA1 receptors are present over the entire brain, but in highest numbers in the medulla oblongata and the substantia nigra. Recent studies have also observed that FFA1 was present in the olfactory bulb, striatum, hippocampus, midbrain, hypothalamus, cerebellum, cerebral cortex and in the spinal cord. Fatty acids play an important role in normal brain development as well as maintaining proper neuronal function. It has been found that certain fatty acids that are in abundance in the brain may be linked with FFA1. These fatty acids likely activate FFA1, inducing an intracellular response. It has been found that docosahexaenoic
Anatomy of the cerebellum pathway transmits signals that inform the cerebellum about the movement in progress and the upcoming movement. This helps the continuous adjustment of motor activity. The initiation of the movement is relayed to cerebellum via the corticoreticulocerebellar pathway. Those synapse ipsilaterally in the reticular formation, then via the inferior and middle peduncles into the cerebellar vermis. The motor cortex and somatosensory cortex projects onto the ipsilateral inferior and accessory olivary nuclei, then forming the olivocerebellar tract. Cortico-olivary fibers synapse bilaterally in the inferior olivary nucleus. The order is preserved in the olivocerebellar tract projections onto the ‘body maps’ in the contralateral