Versican other inflammatory cells) can migrate more easily through extracellular matrix that has a higher versican content. Deposits of versican are not present in normal skin but are found in the reticular dermis during keloid scarring, a condition where scar formation becomes uncontrolled and overgrowth of skin tissue occurs at the site of the wound. Versican has been shown to interact with hyaluronan and a link protein (hyaluronan and proteoglycan link protein 1; HAPLN1). Versican Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissues. It is encoded by the "VCAN" gene. Versican is a
Scar Tissue (book) taken from the single "Scar Tissue" released five years earlier on the Red Hot Chili Peppers album "Californication". According to the book, Kiedis' first drug experience was with his father Blackie Dammett, a former drug dealer, at age eleven. By the time his band formed and became more popular in the 1980s, he and former bandmate Hillel Slovak had severe drug addictions. On Slovak's death from overdose in 1988, Kiedis writes that he was so shaken that he skipped town, missing the funeral. Kiedis had no idea what to do without his friend. His death only made matters worse, and