Nucleated red blood cell nucleated RBCs are found only in the circulation of fetuses and newborn infants. After infancy, RBCs normally only contain a nucleus during the very early stages of the cell's life, and the nucleus is ejected as a normal part of cellular differentiation before the cell is released into the bloodstream. Thus, if NRBCs are seen on an adult's peripheral blood smear, it suggests that there is a very high demand for the bone marrow to produce RBCs, and immature RBCs are being released into circulation. Possible pathologic causes include anemia, myelofibrosis, thalassemia, miliary tuberculosis, cancers involving bone marrow (myelomas, leukemias,
Blood red dark red state, but quickly oxygenates upon exposure to air, turning a brighter shade of red. This happens more quickly with smaller volumes of blood such as a pinprick and less quickly from cuts or punctures that cause greater blood flows such as a puncture in the basilic vein: all blood collected during a phlebotomy procedure is deoxygenated blood, and it does not usually have a chance to become oxygenated upon leaving the body. Arterial blood, which is already oxygenated, is also already a brighter shade of red— this is the blood see from a pulsating neck, arm, or leg