Lateral hypothalamus an OX1-induced CB1 pressor response in the rostral ventrolateral medulla. Narcolepsy is associated with a marked reduction in the number of orexinergic projection neurons from the lateral hypothalamus and very low orexin peptides in cerebrospinal fluid. This has been identified as the mechanism responsible for narcoleptic symptoms. Evidence suggest that OX1 neurons that synapse onto the dorsal nucleus of the vagus nerve and parts of the brain stem may play a role in the pathophysiology of chronic pain and visceral hypersensitivity in functional gastrointestinal disorders. Lateral hypothalamus The lateral hypothalamus, also called the lateral hypothalamic area, contains the primary orexinergic
Anatomy of the cerebellum association areas linked to the cerebellum by corticopontocerebellar fibres, the cognitive affective syndrome may occur. This results in cognitive defects in the form of diminished reasoning power, inattention, grammatical errors in speech, poor spatial sense, and patchy memory loss. Three arteries supply blood to the cerebellum (Fig. 7): the superior cerebellar artery (SCA), anterior inferior cerebellar artery (AICA), and posterior inferior cerebellar artery (PICA). The SCA branches off the lateral portion of the basilar artery, just inferior to its bifurcation into the posterior cerebral artery. Here, it wraps posteriorly around the pons (to which it also supplies blood) before reaching