Pacemaker current on hyperpolarization, and very slow kinetics. The funny current is highly expressed in spontaneously active cardiac regions, such as the sinoatrial node (SAN, the natural pacemaker region), the atrioventricular node (AVN) and the Purkinje fibres of conduction tissue. The funny current is a mixed sodium–potassium current that activates upon hyperpolarization at voltages in the diastolic range (normally from −60/−70 mV to −40 mV). When, at the end of a sinoatrial action potential, the membrane repolarizes below the I threshold (about −40/−50 mV), the funny current is activated and supplies inward current, which is responsible for starting the diastolic depolarization phase
Longitude of the ascending node Longitude of the ascending node The longitude of the ascending node (☊ or Ω) is one of the orbital elements used to specify the orbit of an object in space. It is the angle from a reference direction, called the "origin of longitude", to the direction of the ascending node, measured in a reference plane. The ascending node is the point where the orbit of the object passes through the plane of reference, as seen in the adjacent image. Commonly used reference planes and origins of longitude include: In the case of a binary star known only from visual observations,