Sinoatrial node rate, and increasing heart rate. An increase in heart rate is known as positive chronotropy. The parasympathetic nerves supplying the SA node (in particular the Vagus nerves) originate in the brain. These nerves release a neurotransmitter called acetylcholine (ACh). ACh binds to a receptor called an M2 muscarinic receptor, located on the SA node membrane. Activation of this M2 receptor, then activates a protein called a G-protein (in particular G protein, i for inhibitory). Activation of this G-protein, blocks the cAMP pathway, reducing its effects, therefore inhibiting sympathetic activity and slowing action potential production. As well as this, the G-protein
Node (physics) the ratio of the amplitude of the wave at the antinode to the amplitude at the node. In resonance of a two dimensional surface or membrane, such as a drumhead or vibrating metal plate, the nodes become nodal lines, lines on the surface where the surface is motionless, dividing the surface into separate regions vibrating with opposite phase. These can be made visible by sprinkling sand on the surface, and the intricate patterns of lines resulting are called Chladni figures. In transmission lines a voltage node is a current antinode, and a voltage antinode is a current node. Nodes are