Endocrine disruptor endocrine-disrupting chemicals (EDCs) specifically listing obesity, diabetes, female reproduction, male reproduction, hormone-sensitive cancers in females, prostate cancer in males, thyroid, and neurodevelopment and neuroendocrine systems as being affected biological aspects of being exposed to EDCs. The critical period of development for most organisms is between the transition from a fertilized egg into a fully formed infant. As the cells begin to grow and differentiate, there are critical balances of hormones and protein changes that must occur. Therefore, a dose of disrupting chemicals may do substantial damage to a developing fetus. The same dose may not significantly affect adult mothers. There
Endocrine gland (erythropoietin and renin); the thymus; skin (cholecalciferol); and adipose tissue (leptin and resistin). Endocrine glands derive from all three germ layers. The natural decrease in function of the female’s ovaries during late middle age results in menopause. The efficiency of all endocrine glands seems to decrease gradually as aging occurs. This leads to a generalized increase in the incidence of diabetes mellitus and a lower metabolic rate. Local chemical messengers, not generally considered part of the endocrine system, include autocrines, which act on the cells that secrete them, and paracrines, which act on a different cell type nearby. The ability