Valerian (herb) particular binding site. Hydrophilic extractions of the herb commonly sold over the counter, however, probably do not contain significant amounts of isovaltrate. Valerenic acid in valerian stimulates serotonin receptors as a partial agonist, including 5-HT which is implicated in the sleep-wake cycle. The chief constituent of valerian is a yellowish-green to brownish-yellow oil present in the dried root, varying in content from 0.5 to 2.0%. This variation in quantity may be determined by location; a dry, stony soil yields a root richer in oil than moist, fertile soil. The volatile oils that form the active ingredient are pungent, somewhat reminiscent
Valerian (emperor) the post. During the reign of Decius he was left in charge of affairs in Rome when that prince left for his ill-fated last campaign in "Illyricum". Under Trebonianus Gallus he was appointed "dux" of an army probably drawn from the garrisons of the German provinces which seems to have been ultimately intended for use in a war against the Persians. However, when Trebonianus Gallus had to deal with the rebellion of Aemilianus in 253 AD it was to Valerian he turned for assistance in crushing the attempted usurpation. Valerian headed south but was too late: Gallus was killed by