Pituitary gland protective bony enclosure called the sella turcica. It is composed of three lobes: anterior, intermediate, and posterior. In many animals, these three lobes are distinct.The intermediate is avascular and almost absent in human beings. The intermediate lobe is present in many lower animal species, in particular in rodents, mice and rats, that have been used extensively to study pituitary development and function. In all animals, the fleshy, glandular anterior pituitary is distinct from the neural composition of the posterior pituitary, which is an extension of the hypothalamus. The anterior pituitary arises from an invagination of the oral ectoderm and forms
Pituitary gland correlation between pituitary gland volume and Social Anxiety subscale scores was identified which provided a basis for exploring mediation. Again controlling for age, sex, and BMI, DHEA and DHEA-S have been found to be predictive of larger pituitary gland volume, which was also associated with increased ratings of social anxiety. This research provides evidence that pituitary gland volume mediates the link between higher DHEA(S) levels (associated with relatively early adrenarche) and traits associated with social anxiety. Children who experience early adrenarcheal development tend to have larger pituitary gland volume compared to children with later adrenarcheal development. The Greek physician Galen