Hyaline layer of Hopewell-Smith derivative proteins, such as Emdogain, in trying to stimulate reproduction of cementum in periodontal bony defects is based on the presence of enamel matrix-like proteins within the hyaline layer. Hyaline layer of Hopewell-Smith In tooth development, the hyaline layer of Hopewell-Smith is the most peripheral layer of initially unmineralized dentin that forms immediately subjacent to the cementodentinal junction (CDJ). It eventually mineralizes, but not before the rest of the dentin is already mineralized. It is 0.5-0.8 µm thick and contains enamel matrix-like protein as well as the proteins one would expect to find in dentin. It is into this hyaline
Human tooth forces. As teeth flex under pressure, the arrangement of teeth touching each other, known as occlusion, causes tension on one side of the tooth and compression on the other side of the tooth. This is believed to cause V-shaped depressions on the side under tension and C-shaped depressions on the side under compression. When tooth destruction occurs at the roots of teeth, the process is referred to as internal resorption, when caused by cells within the pulp, or external resorption, when caused by cells in the periodontal ligament. Discoloration of teeth may result from bacteria stains, tobacco, tea, coffee, foods