Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
Acid Tests Acid Tests The Acid Tests were a series of parties held by author Ken Kesey primarily in the San Francisco Bay Area during the mid-1960s, centered entirely on the use of, and advocacy of, the psychedelic drug LSD, also known as "acid". LSD-25 was not made illegal in California until October 6, 1966. The name "Acid Test" was coined by Kesey, after the term "acid test" used by gold miners in the 1850s. He began throwing parties at his farm at La Honda, California. The Merry Pranksters were central to organizing the Acid Tests, including Pranksters such as Lee Quarnstrom