Human digestive system in the small intestine. Water and minerals are reabsorbed back into the blood in the colon of the large intestine, where the environment is slightly acidic. Some vitamins, such as biotin and vitamin K produced by bacteria in the gut flora of the colon are also absorbed. The parietal cells in the fundus of the stomach, produce a glycoprotein called intrinsic factor which is essential for the absorption of vitamin B12. Vitamin B12 (cobalamin), is carried to, and through the stomach, bound to a glycoprotein secreted by the salivary glands - transcobalamin I also called haptocorrin, which protects the acid-sensitive
Digestive biscuit culture, the digestive is ranked the fourth most popular biscuit for "dunking" into tea, with the chocolate digestive coming in at number one. In 1839, digestives were first developed in the United Kingdom by two Scottish doctors to aid digestion. Digestives featured in advertisements for the Berkshire-based biscuit company Huntley & Palmers in 1876, with a recipe being given in Cassell's "New Universal Cookery Book" of 1894. In 1851 an issue of The Lancet London's advertising section offered "brown meal" digestive biscuits. At the time, it was asserted grain millers knew only of bran and endosperm. After 10% of the