Hair coloring by lay people may not be sufficiently accurate. Hair that has been damaged by excessive exposure to chemicals is considered "over-processed". This results in dry, rough and fragile hair. In extreme cases, the hair can be so damaged that it breaks off entirely. The main cases of hair breakage are: Lack of moisture and oils, poor diet, stress, over processing or illness. Skin and fingernails are made of a similar type of keratinized protein as hair. That means that drips, slips and extra hair tint around the hairline can result in patches of discolored skin. This is more common with
Protein domain Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. There are now over 3,000 DUF families within the Pfam database representing over 20% of known families. "This article incorporates text and figures from George, R. A. (2002) "Predicting Structural Domains in Proteins" Thesis, University College London, which were contributed by its author." Protein domain A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can