Bladder outlet obstruction but still have normal renal architecture. This leads to a decrease in the number of nephrons, or functional units of the kidney. Malformation of kidney or bladder architecture. A dysplastic kidney is typically small for age and may contain cysts. A multicystic dysplastic kidney is an extreme example of renal dysplasia. Dilation of the renal pelvis, ureters, or both. Also called hydronephrosis. Kidneys and ureters located in incorrect position, including horseshoe kidney and ectopic ureters. Bladder outlet obstruction is classified based on where along the urinary tract the obstruction occurs, including upper urinary tract obstruction and lower urinary tract obstruction.
Urinary bladder that protects the cells beneath it from urine, the urothelium (a form of transitional epithelium), a basement membrane, and the lamina propria. The mucosal lining also offers a urothelial barrier against the passing of infections. The detrusor muscle is a layer of the urinary bladder wall made of smooth muscle fibers arranged in spiral, longitudinal, and circular bundles. Stretch receptors in the bladder signal the parasympathetic nervous system to stimulate the muscarinic receptors in the detrusor to contract the muscle when the bladder is extended. This encourages the bladder to expel urine through the urethra. The main receptor activated is