Rosalind Franklin and DNA Rosalind Franklin and DNA Rosalind Franklin and DNA is a biography of an English chemist Rosalind Franklin (1920–1958) written by her American friend Anne Sayre in 1975. Franklin was a physical chemist who made pivotal research in the discovery of the structure of DNA, known as "the most important discovery" in biology. DNA itself had become "life's most famous molecule". While working at the King's College London in 1951, she discovered two types of DNA called A-DNA and B-DNA. Her X-ray images of DNA indicated helical structure. Her X-ray image of B-DNA (called Photo 51) taken in 1952 became the
Francis Crick collected by Gosling and Franklin provided the best evidence for the helical nature of DNA. Franklin's experimental work thus proved crucial in Watson and Crick's discovery. Her experimental results provided estimates of the water content of DNA crystals, and these results were most consistent with the three sugar-phosphate backbones being on the outside of the molecule. Franklin's X-Ray photograph showed that the backbones had to be on the outside. Although she at first insisted vehemently that her data did not force one to conclude that DNA has a helical structure, in the drafts she submitted in 1953 she argues for