Versican other inflammatory cells) can migrate more easily through extracellular matrix that has a higher versican content. Deposits of versican are not present in normal skin but are found in the reticular dermis during keloid scarring, a condition where scar formation becomes uncontrolled and overgrowth of skin tissue occurs at the site of the wound. Versican has been shown to interact with hyaluronan and a link protein (hyaluronan and proteoglycan link protein 1; HAPLN1). Versican Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissues. It is encoded by the "VCAN" gene. Versican is a
Fibrous dysplasia of bone normal bone and marrow with fibrous tissue. The bony trabeculae are abnormally thin and irregular, and often likened to Chinese characters (bony spicules on biopsy). Fibrous dysplasia is not hereditary, and there has never been a case of transmission from parent to child. X-Ray Bubbly lytic lesion / Ground glass Imaging tests. Computerized tomography or magnetic resonance imaging scans may be used to determine how extensively your bones are affected. Bone scan. This test uses radioactive tracers, which are injected into your bloodstream. The damaged parts of your bones take up more of the tracers, which show up more brightly