Artificial hair integrations is a type of synthetic fiber that can withstand heat up to 400 °F (200 °C), and can actually outlast human hair. It is very similar to human hair given it is tangle-free and has a natural sheen. It can be straightened or curled, however, it takes longer to set and futura cannot be colored. It is sometimes sold as a human hair blend. The human hair shaft is made up of dead, hard protein, called keratin, in three layers. The inner layer is called the medulla and may not be present. The next layer is the cortex and the
Muehrcke's nails nail plate. As such, they do not move with nail growth, and disappear when pressure is applied to the nail (blanching the underlying nail bed): this distinguishes them from "true leukonychia striata" such as Mees' lines. As in Terry's and half-and-half nails, the pattern is thought to be formed by bands of localized edema exerting pressure on the surrounding capillaries. The appearance of Muehrcke's lines is associated specifically with marked hypoalbuminemia (serum albumin ≤ 2.2 g/dL) indicating decreased protein synthesis, which may occur during periods of metabolic stress (e.g. systemic infection, trauma, AIDS, chemotherapy), or in hypoalbuminemic states such as