Relapse levels and a decrease in estradiol levels during the luteal phase. Anxiety, irritability, and depression, three symptoms of both withdrawal and the human menstrual cycle, are most severe in the luteal phase. Symptoms of withdrawal not associated with the cycle, such as hunger, are also enhanced during the luteal phase, which suggests the role of estradiol and progesterone in enhancing symptoms above the naturally occurring level of the menstrual cycle. The symptoms of craving also increase during the luteal phase in humans (it is important to note that the opposite result occurs in female subjects with cocaine addiction suggesting that
Menstrual cycle by women during the peak of their fertility in the menstrual cycle. Moreover, women may demonstrate preference for men with a scent that indicates developmental stability. With regard to women's smell across the cycle, some evidence indicates that men use olfactory cues in order to know if a woman is ovulating. Using a rating of women's odors, women who are ovulating have been rated as more attractive by men. Men demonstrate preferences for the scent of fertile women. Preferences for facial features in mates can also change across the cycle. There has been no difference found in preference for long-term