Salicylic acid 4-aminosalicylic acid, sandulpiride, and landetimide (via Salethamide). Salicylic acid was one of the original starting materials for making acetylsalicylic acid (aspirin) in 1897. Bismuth subsalicylate, a salt of bismuth and salicylic acid, is the active ingredient in stomach relief aids such as Pepto-Bismol, is the main ingredient of Kaopectate and "displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic". Other derivatives include methyl salicylate used as a liniment to soothe joint and muscle pain and choline salicylate used topically to relieve the pain of mouth ulcers. Salicylic acid has the formula CH(OH)COOH, where
Clavulanic acid Clavulanic acid Clavulanic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins. In its most common form, the potassium salt potassium clavulanate is combined with: Clavulanic acid was patented in 1974. For the treatment of pyelonephritis during pregnancy, and for the treatment of pyelonephritis caused by gram-positive organisms, amoxicillin or amoxicillin-clavulanate potassium is preferred. The name is derived from strains of "Streptomyces clavuligerus", which produces clavulanic acid. Clavulanic acid