Henry Jones Shrapnell tympanic membrane is known as "Shrapnell's membrane". During the same year, Shrapnell published two other articles in the same journal, these being in regards to the function of the tympanic membrane and the nerves of the ear. In 1833, he published an article (again in the same journal) on the anatomy of the incus. Henry Jones Shrapnell Henry Jones Shrapnell (1792–1834) was an English anatomist. For a period of time during his career he was a colleague to Edward Jenner (1749-1823), creator of the vaccine for smallpox. Shrapnell is remembered for his pioneer work in otology. He was the first
Membrane stabilizing effect Membrane stabilizing effect Membrane stabilizing effects involve the inhibition or total abolishing of action potentials from being propagated across the membrane. This phenomenon is common in nerve tissues as they are the carrier of impulses from the periphery to the central nervous system. Membrane stabilization is the method through which local anesthetics work. They block the propagation of action potentials across nerve cells, thereby producing a nerve block. Some beta-blockers also possess what is referred to as membrane stabilizing activity (MSA). This effect is similar to the membrane stabilizing activity of sodium channel blockers that represent Class I antiarrhythmics. MSA