Antibiotic resistance in gonorrhea mechanism for beta-lactam resistance. There have been over 200 beta-lactamases described and some of them are antibiotic specific. TEM-1 is a penicillinase specific for penicillins. This enzyme will bind to the beta-lactam ring which is a structural characteristic for beta-lactams and hydrolyze the ring. This renders the antibiotic inactive. The spread of the penicillinase resistance was much faster compared to the chromosomal-mediated resistance mechanisms. The plasmids containing TEM-1 could be passed from bacterium to bacterium via conjugation Quinolones are a class of synthetic antibiotics that inhibit DNA replication, recombination, and repair by interacting with the bacterial DNA gyrase and/or topoisomerase
Antibiotic use in livestock antibiotic given to the livestock. Since the primary study, there have been many well-documented events showing that antibiotic usage in livestock results in direct influence of antibiotic resistance in humans. Major bacterial infections in humans can be traced back to livestock. The family Enterobacteriaceae includes many opportunistic bacteria, including "E. coli", which are commonly found in livestock. Other bacteria include "Klebsiella" and "Staphylococcus aureus". They cause infections in the urinary tract, digestive system, skin, and bloodstream, and account for a significant portion of antibiotic-resistant bacterial infections. The practice of using antibiotics for growth stimulation is problematic for these reasons: Donald