Pancreatic islets and transdifferentiate into beta cells in both healthy and diabetic human and mouse pancreatic islets, a possible future source for beta cell regeneration. Pancreatic islets The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. The pancreatic islets constitute 1 to 2% of the pancreas volume and receive 10–15% of its blood flow. The pancreatic islets are arranged in density routes throughout the human pancreas, and are important in the metabolism of glucose. There are about 3 million islets distributed in the
Would You Rather (film) Would You Rather (film) Would You Rather is a 2012 American psychological horror-thriller film starring Brittany Snow and Jeffrey Combs. It is based on the party game "would you rather", and centers on Snow's character, Iris, as she attends a dinner party, where she must partake in a life-threatening game to help her sick brother secure a donor. The film premiered at Screamfest 2012. Iris, a young woman caring for her sick brother Raleigh, is unable to afford the costs of his treatment for leukemia. Her brother's oncologist, Dr. Barden, introduces Iris to Shepard Lambrick, a philanthropist, who offers her