Stimulus modality lit area, the eyes require time for a good quantity of rhodopsin to regenerate. As more time passes, there is a higher chance that the photons will split an unbleached photopigment because the rate of regeneration will have surpassed the rate of bleaching. This is called adaptation. Humans are able to see an array of colours because light in the visible spectrum is made up of different wavelengths (from 380 to 760 nm). Our ability to see in colour is due to three different cone cells in the retina, containing three different photopigments. The three cones are each specialized to
Gene therapy of the human retina and expressing the therapeutic DNA sequence. Since the cells of the retina are non-dividing, AAV continues to persist and provide expression of the therapeutic DNA sequence over a long time period that can last several years. AAV is capable of transducing multiple cell types within the retina. AAV serotype 2, the most well-studied type of AAV, is commonly administered in one of two routes: intravitreal or subretinal. Using the intravitreal route, AAV is injected in the vitreous humor of the eye. Using the subretinal route, AAV is injected underneath the retina, taking advantage of the potential space between the photoreceptors