Insulin glargine Insulin glargine Insulin glargine, marketed under the names Lantus, among others, is a long-acting basal insulin analogue, given once daily to help control the blood sugar level of those with diabetes. It consists of microcrystals that slowly release insulin, giving a long duration of action of 18 to 26 hours, with a "peakless" profile (according to the insulin glargine package insert). Pharmacokinetically, its steady action can supplement the variable insulin secretion of non-diabetic pancreatic beta cells. Sometimes, in type 2 diabetes and in combination with a short acting sulfonylurea (drugs which stimulate the pancreas to make more insulin), it can
Insulin shock therapy recent films include "Frances" (1982) in which actress Frances Farmer undergoes insulin shock treatment, and "A Beautiful Mind", which depicted genius John Nash undergoing insulin treatment. In an episode of the medical drama "House_M.D.", Dr. House puts himself in an insulin shock to try to make his hallucinations disappear. Insulin shock therapy Insulin shock therapy or insulin coma therapy (ICT) was a form of psychiatric treatment in which patients were repeatedly injected with large doses of insulin in order to produce daily comas over several weeks. It was introduced in 1927 by Austrian-American psychiatrist Manfred Sakel and used extensively in