Liquid helium of liquid water. Helium was first liquefied on July 10, 1908, by the Dutch physicist Heike Kamerlingh Onnes at the University of Leiden in the Netherlands. At that time, helium-3 was unknown because the mass spectrometer had not yet been invented. In more recent decades, liquid helium has been used as a cryogenic refrigerant, and liquid helium is produced commercially for use in superconducting magnets such as those used in magnetic resonance imaging (MRI), nuclear magnetic resonance (NMR), Magnetoencephalography (MEG), and experiments in physics, such as low temperature Mössbauer spectroscopy. The temperature required to produce liquid helium is low because
Big Science expertise only partially overlaps. Galison introduced the notion of "trading zones," borrowed from the sociolinguistic study of pidgins, to characterize how such groups learn to interact. Other historians have postulated many "precursors" to Big Science in earlier times: the Uraniborg of Tycho Brahe (in which massive astronomical instruments were made, often with little practical purpose) and the large cryogenics laboratory established by Heike Kamerlingh Onnes in 1904 have been cited as early examples of Big Science. Big Science Big science is a term used by scientists and historians of science to describe a series of changes in science which occurred