Nirenberg and Leder experiment acid. Oswald Avery discovered that the substance responsible for producing inheritable change in the disease-causing bacteria was neither a protein nor a lipid, rather deoxyribonucleic acid (DNA). He and his colleagues Colin MacLeod and Maclyn McCarty suggested that DNA was responsible for transferring genetic information. Later, Erwin Chargaff discovered that the makeup of DNA differs from one species to another. These experiments helped pave the way for the discovery of the structure of DNA. In 1953, with the help of Maurice Wilkins and Rosalind Franklin’s X-ray crystallography, James Watson and Francis Crick proposed DNA is structured as a double helix.
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid autobiographical account of the discovery of the double-helical, molecular structure of DNA called "The Double Helix", which was not publicly accepted either by Crick or Wilkins. Furthermore, Erwin Chargaff also printed a rather "unsympathetic review" of Watson's book in the March 29, 1968 issue of "Science". In the book, Watson stated among other things that he and Crick had access to some of Franklin's data from a source that she was not aware of, and also that he had seen—without her permission—the B-DNA X-ray diffraction pattern obtained by Franklin and Gosling in May 1952 at King's in London. In particular,