Hemoglobin the iron gets recycled. This process also produces one molecule of carbon monoxide for every molecule of heme degraded. Heme degradation is one of the few natural sources of carbon monoxide in the human body, and is responsible for the normal blood levels of carbon monoxide even in people breathing pure air. The other major final product of heme degradation is bilirubin. Increased levels of this chemical are detected in the blood if red blood cells are being destroyed more rapidly than usual. Improperly degraded hemoglobin protein or hemoglobin that has been released from the blood cells too rapidly can
Hemoglobin D-Punjab the body. Normal red blood cells have hemoglobin A. People with hemoglobin D trait have red blood cells that have normal hemoglobin A and an abnormal hemoglobin. The abnormal hemoglobin is called hemoglobin D..http://www.stjude.org/stjude/v/index.jsp?vgnextoid=30f0db6324d6f110VgnVCM1000001e0215acRCRD Among the seven known types of Hemoglobin D, only Hemoglobin D Punjab can cause a serious hemoglobin disorder. While Hemoglobin D can be detected without a DNA test, one is needed to ascertain that a person who carries Hemoglobin D carries hemoglobin D-Punjab. A single mutation in the HBB gene is called Hemoglobin D Trait. There is no clinical disease detected, however children of affected individuals