Leg hair follicle it pushed older cells out and that is what becomes the leg hair. After the older cells become hard and leave the follicle, they form a hair shaft. The hair shaft is mostly made up of dead tissue and a protein that is known as keratin. It is said that hair growth occurs during the "growing" phase of the follicle, and then retained as dead club hair during the "resting" phase. The old club hair might be lost within the following "growing" phase. Men are seen to be much hairier than women, even though men and women are much
Nestin (protein) of actively growing pluripotent adult stem cells. Green fluorescent protein (GFP), whose expression is driven by the nestin regulatory element in transgenic mice, serves to mark hair follicle stem cells. These cells can differentiate into neurons, glia, keratinocytes, smooth muscle cells and melanocytes in vitro. Thus, hair follicle stem cells provide an effective, accessible, autologous source of stem cells for treatment of peripheral nerve injury. Nestin has recently received attention as a marker for detecting newly formed endothelial cells. Nestin is an angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue. Nestin (protein) has been shown to interact with