Toxicodynamics into awareness by Our Stolen Future by Theo Colborn. Endocrine disrupting chemicals are known to accumulate in body tissue and are highly persistent in the environment. Many toxicants are known EDCs including pesticides, phthalates, phytoestrogens, some industrial/commercial products, and pharmaceuticals. These chemicals are known to cause endocrine disruption via a few different mechanisms. While the mechanism associated with the thyroid hormone receptor is not well understood, two more established mechanisms involve the inhibition of the androgen receptor and activation of the estrogen receptor. Certain toxicants act as endocrine disruptors by interacting with the androgen receptor. DDE is one example of
Building control body Building control body A building control body is an organisation authorised to control building work that is subject to the Building Regulations in England and Wales (similar systems are provided in Northern Ireland, and in Scotland where the term 'building standards' is used). Building control roles are exercised by officers in local authorities and by private sector Approved Inspectors. The title "Building control officer" (BCO) (also known as a "building inspector" or a "building control surveyor") is used predominantly by local authorities, which confer the title of "officer" to many staff who have regulatory, supervision or enforcement roles. Private sector