Human tooth development is postulated that both models influence tooth development at different times. Other structures that may appear in a developing tooth in this stage are enamel knots, enamel cords, and enamel niche. Hard tissues, including enamel and dentin, develop during the next stage of tooth development. This stage is called the crown, or maturation stage, by some researchers. Important cellular changes occur at this time. In prior stages, all of the IEE cells were dividing to increase the overall size of the tooth bud, but rapid dividing, called mitosis, stops during the crown stage at the location where the cusps of
Development of the nervous system intellectual disability. The mammalian central nervous system (CNS) is derived from the ectoderm—the outermost tissue layer—of the embryo. In the third week of human development the neuroectoderm appears and forms the neural plate along the dorsal side of the embryo. The neural plate is the source of the majority of neurons and glial cells of the CNS. A groove forms along the long axis of the neural plate and, by week four of development, the neural plate wraps in on itself to give rise to the neural tube, which is filled with cerebrospinal fluid (CSF). As the embryo develops, the