Pacemaker current on hyperpolarization, and very slow kinetics. The funny current is highly expressed in spontaneously active cardiac regions, such as the sinoatrial node (SAN, the natural pacemaker region), the atrioventricular node (AVN) and the Purkinje fibres of conduction tissue. The funny current is a mixed sodium–potassium current that activates upon hyperpolarization at voltages in the diastolic range (normally from −60/−70 mV to −40 mV). When, at the end of a sinoatrial action potential, the membrane repolarizes below the I threshold (about −40/−50 mV), the funny current is activated and supplies inward current, which is responsible for starting the diastolic depolarization phase
Node graph architecture in which a number of input images have been layered. By connecting many different node types together complex image effects can be produced. The node graph architecture often allows grouping of nodes inside other group nodes. This hides complexity inside of the group nodes, and limits their coupling with other nodes outside the group. This leads to a hierarchy where smaller graphs are embedded in group nodes. In Nuke the group node is simply called the Group node. In the paper Hierarchical Small Worlds in Software Architecture they argue that most large software systems are built in a modular and