Color blindness as part of the retinal damage caused by diabetes. Vitamin A deficiency may also cause color blindness. Some subtle forms of color blindness may be associated with chronic solvent-induced encephalopathy (CSE), caused by long-time exposure to solvent vapors. Red–green color blindness can be caused by ethambutol, a drug used in the treatment of tuberculosis. The typical human retina contains two kinds of light cells: the rod cells (active in low light) and the cone cells (active in normal daylight). Normally, there are three kinds of cone cells, each containing a different pigment, which are activated when the pigments absorb light.
RGB color model the three kinds allows the brain to differentiate a wide gamut of different colors, while being most sensitive (overall) to yellowish-green light and to differences between hues in the green-to-orange region. As an example, suppose that light in the orange range of wavelengths (approximately 577 nm to 597 nm) enters the eye and strikes the retina. Light of these wavelengths would activate both the medium and long wavelength cones of the retina, but not equally—the long-wavelength cells will respond more. The difference in the response can be detected by the brain, and this difference is the basis of our perception