Ventromedial nucleus of the hypothalamus the brain. VMH is also important in mammal play behaviour. Lesions to VMH along with the hippocampus, amygdala, the cerebellum, and the lateral hypothalamus are all linked to reduced play The VMHdm has a role in the male vocalizations and scent marking behaviors. The VMHvl plays a role in sexual behaviors in females (lordosis), thus stimulating their sexual arousal. Bilateral FOS expression in the VMH after repeated seizures is associated with alteration in the severity of flurothyl induced seizures in C57BL/6J mice that are not present in DBA/2J mice. Moreover, bilateral lesions of the VMH are able to block the
Hypothalamus supraoptic nucleus of the hypothalamus produce neurohypophysial hormones, oxytocin and vasopressin. These hormones are released into the blood in the posterior pituitary. Much smaller parvocellular neurosecretory cells, neurons of the paraventricular nucleus, release corticotropin-releasing hormone and other hormones into the hypophyseal portal system, where these hormones diffuse to the anterior pituitary. The hypothalamic nuclei include the following: "See also:" ventrolateral preoptic nucleus, periventricular nucleus. The hypothalamus is highly interconnected with other parts of the central nervous system, in particular the brainstem and its reticular formation. As part of the limbic system, it has connections to other limbic structures including the