Parasympathetic nervous system act in a complementary way increasing or slowing the heart rate. In this context, the vagus nerve acts on sinoatrial node slowing its conduction thus actively modulating vagal tone accordingly. This modulation is mediated by the neurotransmitter acetylcholine and downstream changes to ionic currents and calcium of heart cells. The vagus nerve plays a crucial role in heart rate regulation by modulating the response of sinoatrial node, vagal tone can be quantified by investigating heart rate modulation induced by vagal tone changes. As a general consideration, increased vagal tone (and thus vagal action) is associated with a diminished and more
Node graph architecture Node graph architecture Node graph architecture is a type of software design which builds around modular node components which can be connected to form a graph. Often the software's underlying node graph architecture is also exposed to the end user as a two-dimensional visualization of the node graph. The node graph architecture is popular in the film and computer games industry. There are often many different node types participating in the node graph. For example, in the Nuke Manual they list hundreds of nodes. Each node type performs one specific task. For example, Nuke's Merge node produces an output image