Versican other inflammatory cells) can migrate more easily through extracellular matrix that has a higher versican content. Deposits of versican are not present in normal skin but are found in the reticular dermis during keloid scarring, a condition where scar formation becomes uncontrolled and overgrowth of skin tissue occurs at the site of the wound. Versican has been shown to interact with hyaluronan and a link protein (hyaluronan and proteoglycan link protein 1; HAPLN1). Versican Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissues. It is encoded by the "VCAN" gene. Versican is a
Scar Tissue (novel) read but worth it.” A review in Literature Annotations pointed out: “A hauntingly beautiful narrative, written on several levels from flashback, to pop-scientific journalism (including allusions to the writings of Oliver Sacks), to academic speeches and essays on the nature of death, composed by the protagonist for his students, public, and publishers.” "The Sunday Telegraph" said that "Scar Tissue" was “moving and intellectually challenging. The "New Statesman" claimed that “no recent British novel has traversed the world of reason and emotion, the human presence and its annihilation, so effectively and directly.” According to Connor Taylor, “this novel seems to exhibit