Rostral ventrolateral medulla spinal cord via reticulospinal tract. Physostigmine, a choline-esterase inhibitor, elevates endogenous levels of acetylcholine and causes a rise in blood pressure by stimulation of the RVLM. Orexinergic neurons from the lateral hypothalamus output in the RVLM. Rostral ventrolateral medulla The rostral ventrolateral medulla (RVLM), also known as the pressor area of the medulla, is a brain region that is responsible for basal and reflex control of sympathetic activity associated with cardiovascular function. Abnormally elevated sympathetic activity in the RVLM is associated with various cardiovascular diseases, such as heart failure and hypertension. The RVLM is notably involved in the baroreflex. It
Medulla (hair) Medulla (hair) The medulla is the innermost layer of the hair shaft. This nearly invisible layer is the most soft and fragile, and serves as the pith or marrow of the hair. Scientists are still uncertain about the exact role of the medulla, but they speculate that it is primarily an extension that is more prominent in depigmented (grey or white) hair Human hair is unique in that its medullary index (the fraction of the hair shaft's diameter that the medulla occupies) is very small: generally less than 1/3. Other species will have much larger ratios, usually at least 1/2.