Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian (emperor) and being soon after made prisoner, grew old in ignominious slavery among the Parthians." An early Christian source, Lactantius, thought to be virulently anti-Persian, thanks to the occasional persecution of Christians by some Sasanian monarchs, maintained that, for some time prior to his death, Valerian was subjected to the greatest insults by his captors, such as being used as a human footstool by Shapur when mounting his horse. According to this version of events, after a long period of such treatment, Valerian offered Shapur a huge ransom for his release. In reply, according to one version, Shapur was said to