Pleiotropy to have protein. Sickle cell anemia is a genetic disease that causes deformed red blood cells with a rigid, crescent shape instead of the normal flexible, round shape. It is caused by a change in one nucleotide, a point mutation in the HBB gene. The HBB gene encodes information to make the beta-globin subunit of hemoglobin, which is the protein red blood cells use to carry oxygen throughout the body. Sickle cell anemia occurs when the HBB gene mutation causes both beta-globin subunits of hemoglobin to change into hemoglobinS (HbS). Sickle cell anemia is a pleiotropic disease because the expression
Biofluid dynamics water, solvents, solutions, suspensions, serum, lymph, and blood. The major body fluid which acts as the lifeline of the living organisms is "Blood". Blood is an extremely complex biological fluid. It consists of blood cells suspended in plasma and other different types of cells which include white blood cells, platelets etc. The blood flow in arteries and veins are closely linked to the blood vessel properties. Carrying the oxygen and nutrients to various tissues and organs of our body, delivering carbon dioxide to the lungs and accepting oxygen, bringing the metabolic by products to the kidneys, regulating the body's defence