Asilomar Conference on Recombinant DNA of classical genetics became more apparent. Two main underlying concepts of this tradition were that genes consisted of DNA and that DNA encoded information that determined the processes of replication and protein synthesis. These concepts were embodied in the model of DNA produced through the combined efforts of James Watson, Francis Crick,and Rosalind Franklin. Further research on the Watson-Crick model yielded theoretical advances that were reflected in new capacities to manipulate DNA. One of these capacities was recombinant DNA technology. This technology entails the joining of DNA from different species and the subsequent insertion of the hybrid DNA into a
Non-helical models of DNA structure as evidence that the strands were plectonemically wound together ("i.e.," topologically linked). The publication of the Rodley structure produced a small but significant ripple of interest in the molecular biological community. However, the level of interest was sufficiently high so that Crick - by that time one of the world’s most influential scientists - publicly suggested that the SBS structure (whose existence he doubted) should be laid to rest by intentionally creating it. Then, he reasoned, its properties could be ascertained, and then shown to be abnormal with respect to the known properties of native DNA. An investigation by Stettler