Allergic inflammation immediate allergic reaction or as a Type I allergic reaction. The reaction is caused by the release of histamine and mast cell granule proteins by a process called degranulation, as well as the production of leukotrienes, prostaglandins and cytokines, by mast cells following the cross-linking of allergen specific IgE molecules bound to mast cell FcεRI receptors. These mediators affect nerve cells causing itching, smooth muscle cells causing contraction (leading to the airway narrowing seen in allergic asthma), goblet cells causing mucus production, and endothelial cells causing vasodilatation and edema. The late phase of a Type 1 reaction (which develops 8–12
Pollen calendar Pollen calendar A pollen calendar is used to show the peak pollen times for different types of plant pollen, which causes allergic reactions in certain people. A pollen calendar can be a very useful tool in forensic science, because it can be used to place the month, or week, or date of death. The use of pollen for criminal investigation purposes is called "forensic palynology". However, the use of a pollen calendar to set the date of death should be used with extreme caution, and only by a carefully trained expert witness. The CSI effect has put pressure on some