Pancreatic islets and transdifferentiate into beta cells in both healthy and diabetic human and mouse pancreatic islets, a possible future source for beta cell regeneration. Pancreatic islets The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. The pancreatic islets constitute 1 to 2% of the pancreas volume and receive 10–15% of its blood flow. The pancreatic islets are arranged in density routes throughout the human pancreas, and are important in the metabolism of glucose. There are about 3 million islets distributed in the
Ryan Langerhans of the independent Atlantic League. Langerhans was signed to a minor league contract and assigned to the Buffalo Bisons again on August 22, 2013. When the Bisons season ended, Langerhans asked for and received his release, and returned to the Sugar Land Skeeters for their playoff run. On September 26, Langerhans again signed with the Blue Jays. This time a major league contract as the Blue Jays were short on position players. He became a free agent on October 8, 2013. He hit a game-winning home run against J.P. Howell on August 7, 2009, with two outs in the bottom