Sickle cell disease other genetic diseases) among African Americans compared to West Africans. Another factor that limits the spread of sickle cell genes in North America is the relative absence of polygamy, which allows affected males to continue to produce many children with multiple partners. The loss of red blood cell elasticity is central to the pathophysiology of sickle cell disease. Normal red blood cells are quite elastic, which allows the cells to deform to pass through capillaries. In sickle cell disease, low oxygen tension promotes red blood cell sickling and repeated episodes of sickling damage the cell membrane and decrease the cell's
White blood cell underlying cause, though the cause may not always be found. The complete blood cell count is a blood panel that includes the overall WBC count and various subsets such as the absolute neutrophil count. Reference ranges for blood tests specify the typical counts in healthy people. TLC- (Total leucocyte count): Normal TLC in an adult person is 6000-8000WBC/mm^3 of blood. DLC- (Differential leucocyte count): Number/ (%) of different type of leucocyte in per cubic mm. of blood. White blood cell White blood cells (also called leukocytes or leucocytes and abbreviated as WBCs) are the cells of the immune system that