Light skin of UVA can penetrate deeply into the dermis in persons with light skin pigmentation with little protective melanin pigment. The characteristic of fair skin, red hair, and freckling is associated with high amount of pheomelanin, little amounts of eumelanin. This phenotype is caused by a loss-of-function mutation in the melanocortin 1 receptor (MC1R) gene. However, variations in the MC1R gene sequence only have considerable influence on pigmentation in populations where red hair and extremely fair skin is prevalent. The gene variation’s primary effect is to promote eumelanin synthesis at the expense of pheomelanin synthesis, although this contributes to very little
Alumina effect pigment of all layers in the pigment structure, including the AlOsubstrate. Analytical investigations show that the thickness range of the aluminum oxide platelets and the resultant pigments can be controlled very precisely. The sparkle effect of the pigments in coating applications is controlled by the quantity of the added pigment. The effect is visible already at concentrations of 0.1% in the paint system. The intensity is steadily increased up to pigment concentrations of about 2%. The single light spots arising from the pigment structure and orientation in the paint system seem to spring back and forth when a painted metal plate