History of diabetes further clarified in 1921, when Sir Frederick Grant Banting and Charles Herbert Best repeated the work of Von Mering and Minkowski, and went further to demonstrate they could reverse induced diabetes in dogs by giving them an extract from the pancreatic islets of Langerhans of healthy dogs. The islets of Langerhans was discovered in 1869 by an anatomist named Paul Langerhans. He identified the keys cells in the pancreas which produce the main substance that controls glucose levels in the body. Banting, Best, and colleagues (especially the chemist Collip) went on to purify the hormone insulin from bovine pancreases at
Beatrice Islets remove South African boxthorn, an introduced species considered to an infestation risk, which occurred either during the 1960s or the 1970s and which resulted in the islets becoming ‘susceptible to erosion, and tides and rough weather’ thereby reducing the ‘once stable vegetated islets to bare, wave-washed sand spits’. Subsequent attempts to stabilise the islets and encourage the deposition of sand were unsuccessful. As of 1987, the islets were reported as existing ‘only as a mudflat/cocklebed which emerges above the sea at low tide.’ The conditions for the creation of The Spit and therefore Beatrice Islets and Busby Islet became possible