Compensatory growth (organ) kidneys. Along with the kidneys, compensatory growth has also been characterized in a number of other tissues and organs including: A large number of growth factors and hormones are involved with compensatory growth, but the exact mechanism is not fully understood and probably varies between different organs. Nevertheless, angiogenic growth factors which control the growth of blood vessels are particularly important because blood flow significantly determines the maximum growth of an organ. Compensatory growth may also refer to the accelerated growth following a period of slowed growth, particularly as a result of nutrient deprivation. Compensatory growth (organ) Compensatory growth is
Blood–brain barrier more likely, aggravated) by a breakdown in the blood–brain barrier. Cerebral edema is the accumulation of excess water in the extracellular space of the brain, which can result when hypoxia causes the blood–brain barrier to open. Many neurodegenerative diseases including synucleinopathies such as Parkinson's, and tauopathies such as Alzheimer's are thought to result from seeded misfolding from pathological extracellular protein variants known as prions. This prion-like hypothesis is gaining support in numerous studies in vitro and involving in vivo intracerebral injection of brain lysates, extracted protein (tau, alpha-synuclein) and synthetically generated fibers in alpha-synucleinopathies. These proteins are also detectable in