Color blindness as part of the retinal damage caused by diabetes. Vitamin A deficiency may also cause color blindness. Some subtle forms of color blindness may be associated with chronic solvent-induced encephalopathy (CSE), caused by long-time exposure to solvent vapors. Red–green color blindness can be caused by ethambutol, a drug used in the treatment of tuberculosis. The typical human retina contains two kinds of light cells: the rod cells (active in low light) and the cone cells (active in normal daylight). Normally, there are three kinds of cone cells, each containing a different pigment, which are activated when the pigments absorb light.
Retina horizontal cell proposed. Horizontal cells span across photoreceptors and summate inputs before synapsing onto photoreceptor cells. Horizontal cells may also synapse onto bipolar cells, but this remains uncertain. There is a greater density of horizontal cells towards the central region of the retina. In the cat, it is observed that A-type horizontal cells have a density of 225 cells/mm near the center of the retina and a density of 120 cells/mm in more peripheral retina. Horizontal cells and other retinal interneuron cells are less likely to be near neighbours of the same subtype than would occur by chance, resulting in ‘exclusion zones’