Compounds of fluorine heavier halogens (chlorine, bromine, and iodine) all form mono-, tri-, and pentafluorides: XF, XF, and XF. Of the neutral +7 species, only iodine heptafluoride is known. While chlorine and bromine heptafluorides are not known, the corresponding cations and , extremely strong oxidizers, are. Astatine is not well-studied, and although there is a report of a non-volatile astatine monofluoride, its existence is debated. Many of the halogen fluorides are powerful fluorinators. Chlorine trifluoride is particularly noteworthy—readily fluorinating asbestos and refractory oxides—and may be even more reactive than chlorine pentafluoride. Used industrially, ClF requires special precautions similar to those for fluorine gas
Biological aspects of fluorine Biological aspects of fluorine Biological aspects of fluorine describes the effects of fluorine-containing compounds with life. Fluorine (F) itself is very rare in everyday life, but hundreds of fluorine-containing compounds occur as minerals, medicines, pesticides, and materials. Naturally occurring organofluorine compounds are extremely rare. Nonetheless, twenty percent of all commercialized pharmaceuticals contain fluorine, examples being Lipitor and Prozac. Manmade fluorinated compounds have also played a role in several noteworthy environmental concerns. Chlorofluorocarbons, once major components of numerous commercial aerosol products, have proven damaging to Earth's ozone layer and resulted in the wide-reaching Montreal Protocol (though in truth the chlorine in