Citrus associated with a 10% reduction in odds of developing breast cancer. Oranges were historically used for their high content of vitamin C, which prevents scurvy. Scurvy is caused by vitamin C deficiency, and can be prevented by having 10 milligrams of vitamin C a day. An early sign of scurvy is fatigue. If ignored, later symptoms are bleeding and bruising easily. British sailors were given a ration of citrus fruits on long voyages to prevent the onset of scurvy, hence the British nickname of Limey. Pectin is a structural heteropolysaccharide contained in the primary cell walls of plants. Limes and
Vitamin B12 deficiency anemia antibodies for parietal cells; however, only 50% of all individuals in the general population with these antibodies have pernicious anemia. Forms of vitamin B deficiency other than PA must be considered in the differential diagnosis of megaloblastic anemia. For example, a B-deficient state which causes megaloblastic anemia and which may be mistaken for classical PA may be caused by infection with the tapeworm "Diphyllobothrium latum", possibly due to the parasite's competition with host for vitamin B. The classic test for PA, the Schilling test, is no longer widely used, as more efficient methods are available. This historic test consisted, in