Tendon the presence of denatured collagen are factors that are believed to cause weakening of the tendon ECM and an increase in the potential for another rupture to occur. In response to repeated mechanical loading or injury, cytokines may be released by tenocytes and can induce the release of MMPs, causing degradation of the ECM and leading to recurring injury and chronic tendinopathies. A variety of other molecules are involved in tendon repair and regeneration. There are five growth factors that have been shown to be significantly upregulated and active during tendon healing: insulin-like growth factor 1 (IGF-I), platelet-derived growth factor
Quadriceps tendon Without the quadriceps tendon, the knee cannot extend. Often, when the tendon is completely torn, part of the kneecap bone will break off with the tendon as well. It can rupture resulting in quadriceps tendon rupture. It has been studied in the analysis of patellofemoral pain syndrome. Quadriceps tendon In human anatomy, the quadriceps tendon allows the quadriceps femoris muscles ("rectus femoris, vastus lateralis, vastus medialis, and vastus intermedius") to converge on the superior aspects of the patella on the anterior of the thigh, which continues as the patellar ligament. A tendon connects muscle to bone, while a ligament connects