Estradiol for tissue of the reproductive organs, supporting the lining of the vagina, the cervical glands, the endometrium, and the lining of the fallopian tubes. It enhances growth of the myometrium. Estradiol appears necessary to maintain oocytes in the ovary. During the menstrual cycle, estradiol produced by the growing follicles triggers, via a positive feedback system, the hypothalamic-pituitary events that lead to the luteinizing hormone surge, inducing ovulation. In the luteal phase, estradiol, in conjunction with progesterone, prepares the endometrium for implantation. During pregnancy, estradiol increases due to placental production. The effect of estradiol, together with estrone and estriol, in pregnancy
Menstrual synchrony of northwestern California, according to one ethnographic study, "all of a household's fertile women who were not pregnant menstruated at the same time..." The phenomenon of menstrual synchrony is the closeness in time of the menstrual cycle onsets of two or more women. The phenomenon is not synchronization in the strict sense of concordance of menstrual cycle onsets but the term "menstrual synchrony" is still used perhaps misleadingly. As an undergraduate, Martha McClintock published the first study on menstrual synchrony; her report detailed the menstrual synchrony of undergraduate women living in a dormitory in Wellesley College. Since then, there have