Parasympathetic nervous system act in a complementary way increasing or slowing the heart rate. In this context, the vagus nerve acts on sinoatrial node slowing its conduction thus actively modulating vagal tone accordingly. This modulation is mediated by the neurotransmitter acetylcholine and downstream changes to ionic currents and calcium of heart cells. The vagus nerve plays a crucial role in heart rate regulation by modulating the response of sinoatrial node, vagal tone can be quantified by investigating heart rate modulation induced by vagal tone changes. As a general consideration, increased vagal tone (and thus vagal action) is associated with a diminished and more
Node deletion nodes are deleted compared to the random removal case. The diameter is doubled when 5% of the nodes are eliminated. This is because removing the hubs seriously changes the topology of the network, most links are removed, so the diameter goes up. Node deletion Node deletion is the procedure of removing a node from a network, where the node is either chosen randomly or directly. Node deletion is used to test the robustness and the attack tolerance of networks. Understanding how a network changes in response to node deletion is critical in many empirical networks. Application varies across many fields,