Sinoatrial node therefore cause ischaemia and cell death in the SA node. This can disrupt the electrical pacemaker function of the SA node, and can result in sick sinus syndrome. If the SA node does not function, or the impulse generated in the SA node is blocked before it travels down the electrical conduction system, a group of cells further down the heart will become its pacemaker. The sinoatrial node was first discovered by a young medical student, Martin Flack, in the heart of a mole, whilst his mentor, Sir Arthur Keith, was on a bicycle ride with his wife. They made
Node-to-node data transfer Node-to-node data transfer In telecommunications, node-to-node data transfer is the movement of data from one node of a network to the next. In the OSI model it is handled by the lowest two layers, the data link layer and the physical layer. In most communication systems, the transmitting point applies source coding, followed by channel coding, and lastly, line coding. This produces the baseband signal. The presence of filters may perform pulse shaping. Some systems then use modulation to multiplex many baseband signals into a broadband signal. The receiver un-does these transformations in reverse order: demodulation, trellis decoding, error detection