Cerebellum a variant of Guillain–Barré syndrome. The human cerebellum changes with age. These changes may differ from those of other parts of the brain. The cerebellum is the youngest brain region (and body part) in centenarians according to an epigenetic biomarker of tissue age known as epigenetic clock: it is about 15 years younger than expected in a centenarian. Further, gene expression patterns in the human cerebellum show less age-related alteration than that in the cerebral cortex. Some studies have reported reductions in numbers of cells or volume of tissue, but the amount of data relating to this question is not
Cerebellum are, however, a number of respects in which the structure of the cerebellum is compartmentalized. There are large compartments that are generally known as "zones"; these can be divided into smaller compartments known as "microzones". The first indications of compartmental structure came from studies of the receptive fields of cells in various parts of the cerebellar cortex. Each body part maps to specific points in the cerebellum, but there are numerous repetitions of the basic map, forming an arrangement that has been called "fractured somatotopy". A clearer indication of compartmentalization is obtained by immunostaining the cerebellum for certain types of