Nav1.5 kb. The gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5’ untranslated region (5’UTR) and exon 28 the 3’ untranslated region (3’UTR) of the RNA. SCN5A is part of a family of 10 genes that encode different types of sodium channels, i.e. brain-type (Na1.1, Na1.2, Na1.3, Na1.6), neuronal channels (Na1.7, Na1.8 and Na1.9), skeletal muscle channels (Na1.4) and the cardiac sodium channel Na1.5. SCN5A is mainly expressed in the heart, where expression is abundant in working myocardium and conduction tissue. In contrast, expression is low in the sinoatrial node and atrioventricular node.
Lunar node Lunar node A lunar node is either of the two orbital nodes of the Moon, that is, the two points at which the orbit of the Moon intersects the ecliptic. The "ascending" (or "north") node is where the Moon moves into the northern ecliptic hemisphere, while the "descending" (or "south") node is where the Moon enters the southern ecliptic hemisphere. A lunar eclipse can occur only when the full Moon is near (within 11° 38' ecliptic longitude) either lunar node, while a solar eclipse can occur only when the new Moon is near (within 17° 25') either lunar node. Because