How Do They Do It? How Do They Do It? How Do They Do It? is a television series produced by Wag TV for Discovery Channel. Each programme explores how 2 or 3 ordinary objects are made and used. The show's slogan is "Behind the ordinary is the extraordinary." The series is broadcast throughout the world on various Discovery-owned networks including: Series 1 and 2, which were co-produced with Rocket Surgery Productions, were narrated by Rupert Degas; series 3 and 4 were narrated by Iain Lee; and series 5 and 6 were narrated by Dominic Frisby. In 2008, the UK's Channel 5 began airing the
Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and . Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) In enzymology, a bis(5'-nucleosyl)-tetraphosphatase (symmetrical) () is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are P1,P4-bis(5'-adenosyl) tetraphosphate and HO, whereas its product is ADP. This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase. Other names in common use include diadenosinetetraphosphatase (symmetrical), dinucleosidetetraphosphatasee (symmetrical), symmetrical diadenosine tetraphosphate hydrolase, adenosine tetraphosphate phosphodiesterase, Ap4A hydrolase, bis(5'-adenosyl)