Glycogen phosphorylase V, McArdle's Disease). More than 65 mutations in the PYGM gene that lead to McArdle disease have been identified to date. Symptoms of McArdle disease include muscle weakness, myalgia, and lack of endurance, all stemming from low glucose levels in muscle tissue. Mutations in the liver isoform of glycogen phosphorylase (PYGL) are associated with Hers' Disease (glycogen storage disease type VI). Hers' disease is often associated with mild symptoms normally limited to hypoglycemia, and is sometimes difficult to diagnose due to residual enzyme activity. The brain isoform of glycogen phosphorylase (PYGB) has been proposed as a biomarker for gastric cancer.
The body in traditional Chinese medicine trunk, and ends under the collarbone. (2)The Bladder, a Yang organ, stores and removes fluid from the body by receiving Kidney chi. Imbalance of the Bladder leads to frequent or uncontrolled urination. The Bladder Meridian begins in the corner of the eye, moves down the back, and ends on the back of the knee. The Bladder also has another line, which starts alongside the previous line, moves down to the outer edge of the foot and ends on the small toe. The body in traditional Chinese medicine The model of the body in traditional Chinese medicine (TCM) has the following