DNA Day celebration, not an annual holiday. Every year from 2003 onward, annual DNA Day celebrations have been organized by the National Human Genome Research Institute (NHGRI), starting as early as April 23 in 2010, April 15 in 2011 and April 20 in 2012. April 25 has since been declared "International DNA Day" and "World DNA Day" by several groups. DNA Day National DNA Day is a holiday celebrated on April 25. It commemorates the day in 1953 when James Watson, Francis Crick, Maurice Wilkins, Rosalind Franklin and colleagues published papers in the journal Nature on the structure of DNA. Furthermore, on
Prokaryotic DNA replication attack onto the alpha phosphate of the deoxyribonucleotide and orient and stabilize the negatively charged triphosphate on the deoxyribonucleotide. Nucleophilic attack by the 3' OH on the alpha phosphate releases pyrophosphate, which is then subsequently hydrolyzed (by inorganic phosphatase) into two phosphates. This hydrolysis drives DNA synthesis to completion. Furthermore, DNA polymerase III must be able to distinguish between correctly paired bases and incorrectly paired bases. This is accomplished by distinguishing Watson-Crick base pairs through the use of an active site pocket that is complementary in shape to the structure of correctly paired nucleotides. This pocket has a tyrosine residue