Glycogen debranching enzyme at Duke University suggest that the human AGL gene contains at minimum 2 promotor regions, sites where the transcription of the gene begins, that result in differential expression of isoform, different forms of the same protein, mRNAs in a manner that is specific for different tissues. When GDE activity is compromised, the body cannot effectively release stored glycogen, type III Glycogen Storage Disease (debrancher deficiency), an autosomal recessive disorder, can result. In GSD III glycogen breakdown is incomplete and there is accumulation of abnormal glycogen with short outer branches. Most patients exhibit GDE defiency in both liver and muscle (TypeIIIa),
Campbell's Stores 1858-59, Sands Directory lists the following at Campbell's Wharf: Campbell & Co; Sugar Company's stores; JC Dibbs & Co, commission agents and wharfingers; Robert Nash, storekeeper; WH Eldred, Capt, Chili Flour Co; Chilian Consulate - Consul, WH Eldred. In 1861, it shows: Campbell & Co; Colonial Sugar Refining Co, stores; Peruvian guano stores; George Lloyd & Co stores; Robey & Co's stores; George Lewis custom house officer; and WH Eldred, broker & general agent. In 1863, it shows: 4. Merry Willis and Co, merchants; 3. Henry Fisher & Son, sugar factors; 2. Brown & Co, merchants; 1. EM Sayers &