Blood gas tension constant 0.0031 represents the amount of oxygen dissolved in plasma. The dissolved-oxygen term is generally small relative to the term for hemoglobin-bound oxygen, but becomes significant at very high PO (as in a hyperbaric chamber) or in severe anemia. This is an estimation and does not account for differences in temperature, pH and concentrations of 2,3 DPG. Blood gas tension Blood gas tension refers to the partial pressure of gases in blood. There are several significant purposes for measuring gas tension; the most common gas tensions measured are oxygen tension (PO), the carbon dioxide tension (PCO) and carbon monoxide tension
Hemoglobin Hopkins-2 endocarditis and thrombosis. Osler's initial observations of platelets catalyzed the study of blood and hematology at Hopkins and in other research environments. Beginning in 1920, doctors at Johns Hopkins Hospital conducted research on sickle cell anemia, or sickle cell disease. Although their conclusions surrounding the disease are outdated, Doctors Taliaferro and Huck discovered a latent form of sickle cell anemia. Their study on sickle cell anemia was the first of many to occur at Hopkins. In 1940, Irving Sherman, a medical student at Johns Hopkins, correctly identified the deoxygenation of hemoglobin in sickle cell patients after he noted refraction patterns