Versican other inflammatory cells) can migrate more easily through extracellular matrix that has a higher versican content. Deposits of versican are not present in normal skin but are found in the reticular dermis during keloid scarring, a condition where scar formation becomes uncontrolled and overgrowth of skin tissue occurs at the site of the wound. Versican has been shown to interact with hyaluronan and a link protein (hyaluronan and proteoglycan link protein 1; HAPLN1). Versican Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissues. It is encoded by the "VCAN" gene. Versican is a
Scar Tissue (novel) death, even once he has lost both his parents, concluding that he “know[s] that there is a life beyond this death, a time beyond this time. I know that at the very last moment…I will be face to face at last with a pure and heartless reality beyond anything a living soul can possibly imagine.” The themes of the book are: mental illness, Alzheimer's, aging, adolescence, survival, suffering, familial relationships, love, marital discord, father-son relationship, chronic illness, nursing. Shortlisted for the Booker Prize (1994) and Whitbread Awards. "Scar Tissue" has received substantial acclaim. It was described as: “powerful Alzheimer's novel