Allergic inflammation immediate allergic reaction or as a Type I allergic reaction. The reaction is caused by the release of histamine and mast cell granule proteins by a process called degranulation, as well as the production of leukotrienes, prostaglandins and cytokines, by mast cells following the cross-linking of allergen specific IgE molecules bound to mast cell FcεRI receptors. These mediators affect nerve cells causing itching, smooth muscle cells causing contraction (leading to the airway narrowing seen in allergic asthma), goblet cells causing mucus production, and endothelial cells causing vasodilatation and edema. The late phase of a Type 1 reaction (which develops 8–12
What Bird is That? Edition What Bird is That?" was published by Australia's Heritage Publishing in 2011, the latest release of Cayley’s “big bird book” complete with Lindsey’s revisions. It is 832 pages, features 769 birds and includes all 460 of Cayley’s full-colour paintings, many showing groups of related birds. New to this edition was an accompanying e-book "What Bird Call is That?", which identifies and illustrates 101 birds from "What Bird is That?", as well as providing sound files of each featured bird’s distinctive call. The sound files were provided by David Stewart. "What Bird is That?" plays a central role in Australian