Henry Jones Shrapnell tympanic membrane is known as "Shrapnell's membrane". During the same year, Shrapnell published two other articles in the same journal, these being in regards to the function of the tympanic membrane and the nerves of the ear. In 1833, he published an article (again in the same journal) on the anatomy of the incus. Henry Jones Shrapnell Henry Jones Shrapnell (1792–1834) was an English anatomist. For a period of time during his career he was a colleague to Edward Jenner (1749-1823), creator of the vaccine for smallpox. Shrapnell is remembered for his pioneer work in otology. He was the first
Membrane curvature several amphipathic alpha helices that allows it to partition between the hydrophobic core of the membrane and surrounding aqueous, hydrophilic environment. Another interesting characteristic of epsin and other proteins that bind to membranes is the fact that it shows high binding affinity for a fairly common membrane lipid, phosphatidylinositol 4,5-bisphosphate (PI-4,5-P2). Unlike other proteins that simply bend the membrane through sheer rigidity, epsin is a globular soluble protein and thus not rigid. The insertion of its helices into the membrane force the neighboring lipids of the leaflet that has been bound to expand laterally. This displacement of lipids on only