Asilomar Conference on Recombinant DNA of classical genetics became more apparent. Two main underlying concepts of this tradition were that genes consisted of DNA and that DNA encoded information that determined the processes of replication and protein synthesis. These concepts were embodied in the model of DNA produced through the combined efforts of James Watson, Francis Crick,and Rosalind Franklin. Further research on the Watson-Crick model yielded theoretical advances that were reflected in new capacities to manipulate DNA. One of these capacities was recombinant DNA technology. This technology entails the joining of DNA from different species and the subsequent insertion of the hybrid DNA into a
Molecular models of DNA omit both water and ions dynamically bound to B-DNA, and are thus less useful for understanding the dynamic behaviors of B-DNA "in vivo". The physical and mathematical analysis of X-ray and spectroscopic data for paracrystalline B-DNA is thus far more complex than that of crystalline, A-DNA X-ray diffraction patterns. The paracrystal model is also important for DNA technological applications such as DNA nanotechnology. Novel methods that combine X-ray diffraction of DNA with X-ray microscopy in hydrated living cells are now also being developed. There are various uses of DNA molecular modeling in Genomics and Biotechnology research applications, from DNA repair