Spectral sensitivity Spectral sensitivity Spectral sensitivity is the relative efficiency of detection, of light or other signal, as a function of the frequency or wavelength of the signal. In visual neuroscience, spectral sensitivity is used to describe the different characteristics of the photopigments in the rod cells and cone cells in the retina of the eye. It is known that the rod cells are more suited to scotopic vision and cone cells to photopic vision, and that they differ in their sensitivity to different wavelengths of light. It has been established that the maximum spectral sensitivity of the human eye under daylight
Gene therapy of the human retina vector on embryonic day 14 shows efficient transduction of retinal pigment epithelium in the RPE65-/- knockout mice and rescues visual functions. This shows successful gene therapy can be attributed to early intraocular deliver to the diseased animal. Juvenile retinoschisis is a disease that affects the nerve tissue in the eye. This disease is an X-linked recessive degenerative disease of the central macula region, and it is caused by mutation in the RSI gene encoding the protein retinoschisin. Retinoschisin is produced in the photoreceptor and bipolar cells and it is critical in maintaining the synaptic integrity of the retina. Specifically the