Sexual differentiation in humans any androgen can cause external masculinization. The most potent is dihydrotestosterone (DHT), generated from testosterone in skin and genital tissue by the action of 5α-reductase. A male fetus may be incompletely masculinized if this enzyme is deficient. In some diseases and circumstances, other androgens may be present in high enough concentrations to cause partial or (rarely) complete masculinization of the external genitalia of a genetically female fetus. The testes begin to secrete three hormones that influence the male internal and external genitalia. They secrete anti-müllerian hormone, testosterone, and Dihydrotestosterone. anti-Müllerian hormone (AMH) causes the paramesonephric ducts to regress. Testosterone, which
Asia Pacific Coalition on Male Sexual Health Asia Pacific Coalition on Male Sexual Health The Asia Pacific Coalition on Male Sexual Health, also known as APCOM, is a network of non-profit organizations which share the mission of improving male sexual health in South Asia, East Asia, and the Pacific Islands. APCOM was launched in July 2007 after delegates to the Delhi 2006 International Consultation on Male Sexual Health and HIV in Asia and the Pacific identified a need for more organization in the field of male sexual health. APCOM was founded as an autonomous, regional coalition of citizen groups, government representatives, funders, technical consultants and the United