Exercise physiology loss of integrity to the blood brain barrier. Hyperthermia also can lower cerebral blood flow, and raise brain temperature. Researchers once attributed fatigue to a build-up of lactic acid in muscles. However, this is no longer believed. Rather, lactate may stop muscle fatigue by keeping muscles fully responding to nerve signals. The available oxygen and energy supply, and disturbances of muscle ion homeostasis are the main factor determining exercise performance, at least during brief very intense exercise. Each muscle contraction involves an action potential that activates voltage sensors, and so releases Ca ions from the muscle fibre’s sarcoplasmic reticulum. The
Muscles of the hand nerve innervates the finger extensors and the thumb abductor; that is, the muscles that extend at the wrist and metacarpophalangeal joints (knuckles) and abduct and extend the thumb. The median nerve innervates the flexors of the wrist and digits, the abductors and opponens of the thumb, the first and second lumbrical. The ulnar nerve innervates the remaining intrinsic muscles of the hand. All muscles of the hand are innervated by the brachial plexus (C5–T1) and can be classified by innervation: Muscles of the hand The muscles of the hand are the skeletal muscles responsible for the movement of the hand