Antibiotic antibiotic therapy. The antibiotic treatment may select for bacterial strains with physiologically or genetically enhanced capacity to survive high doses of antibiotics. Under certain conditions, it may result in preferential growth of resistant bacteria, while growth of susceptible bacteria is inhibited by the drug. For example, antibacterial selection for strains having previously acquired antibacterial-resistance genes was demonstrated in 1943 by the Luria–Delbrück experiment. Antibiotics such as penicillin and erythromycin, which used to have a high efficacy against many bacterial species and strains, have become less effective, due to the increased resistance of many bacterial strains. Resistance may take the form
Antibiotic-Antimycotic reproductive techniques. In animal cell culture, Antibiotic-Antimycotic solution was used to wash goat embryos prior to incubation with oviduct and uterine cells, for enhanced development of embryos into blastocysts. In large-scale bioreactors, contamination risk is high due to the connection of tubing from inlets and outlets. Antibiotic-Antimycotic solution was incorporated into media for culturing suspension-adapted human embryonic kidney (HEK) 293 cell lines in bioreactors. The ability to isolate cell types is an important component of tissue engineering. In order to prevent contamination during seeding of human fibroblasts followed by endothelial cells on polymeric scaffolds, Antibiotic-Antimycotic solution was used during the