Digestion (largely the glucose-insulin system) have been uncovered in recent years. Digestion is a complex process controlled by several factors. pH plays a crucial role in a normally functioning digestive tract. In the mouth, pharynx and esophagus, pH is typically about 6.8, very weakly acidic. Saliva controls pH in this region of the digestive tract. Salivary amylase is contained in saliva and starts the breakdown of carbohydrates into monosaccharides. Most digestive enzymes are sensitive to pH and will denature in a high or low pH environment. The stomach's high acidity inhibits the breakdown of carbohydrates within it. This acidity confers two
Calponin 3, acidic Calponin 3, acidic Calponin 3. acidic is a protein that in humans is encoded by the "CNN3" gene. The "CNN3" gene is located at 1p22-p21 in the human chromosomal genome. "CNN3" gene contains 7 exons and encodes calponin 3, a 36.4-kDa protein consisting of 329 amino acids with isoelectric point (pI) of 5.84. Calponin 3 is known as acidic calponin. Among three isoforms of calponin, less is known for the gene regulation and function of calponin 3. Nonetheless, much has been learned from extensive studies on the homologous genes "CNN1" and "CNN2" that encode calponin 1 and calponin 2. "CNN3"