Autoimmune GFAP Astrocytopathy The scar is formed by astrocytes interacting with fibrous tissue to re-establish the glial margins around the central injury core and is partially caused by up-regulation of GFAP. The reported symptoms are: Under MRI these patients show a characteristic radial enhancing and laminar patterns. In an early report, most patients had brain abnormalities (89.5%), of which eight (42.1%) revealed the characteristic radial enhancing and laminar patterns. Cortical abnormalities were found in one fifth of patients (21.1%). Other abnormalities were found in the hypothalamus, midbrain, pons, medulla cerebellum, meninges and skull. Eleven patients had longitudinally extensive spinal cord lesions. CSF abnormalities
Anterior median fissure of the medulla oblongata join the inferior peduncle. Anterior median fissure of the medulla oblongata The anterior median fissure (ventral or ventromedian fissure) contains a fold of pia mater, and extends along the entire length of the medulla oblongata: It ends at the lower border of the pons in a small triangular expansion, termed the foramen cecum. Its lower part is interrupted by bundles of fibers that cross obliquely from one side to the other, and constitute the pyramidal decussation. Some fibers, termed the anterior external arcuate fibers, emerge from the fissure above this decussation and curve lateralward and upward over the surface of