Nirenberg and Leder experiment acid. Oswald Avery discovered that the substance responsible for producing inheritable change in the disease-causing bacteria was neither a protein nor a lipid, rather deoxyribonucleic acid (DNA). He and his colleagues Colin MacLeod and Maclyn McCarty suggested that DNA was responsible for transferring genetic information. Later, Erwin Chargaff discovered that the makeup of DNA differs from one species to another. These experiments helped pave the way for the discovery of the structure of DNA. In 1953, with the help of Maurice Wilkins and Rosalind Franklin’s X-ray crystallography, James Watson and Francis Crick proposed DNA is structured as a double helix.
Maurice Wilkins deduced from her X-ray diffraction data. Watson and Crick published their proposed DNA double helical structure in a paper in the journal "Nature" in April 1953. In this paper Watson and Crick acknowledged that they had been "stimulated by... the unpublished results and ideas" of Wilkins and Franklin. The first Watson-Crick paper appeared in "Nature" on 25 April 1953. The members of the Cambridge and King's College laboratories agreed to report their interlocking work in three papers with continuous pagination in "Nature". Sir Lawrence Bragg, the director of the Cavendish Laboratory, where Watson and Crick worked, gave a talk at