Light skin of UVA can penetrate deeply into the dermis in persons with light skin pigmentation with little protective melanin pigment. The characteristic of fair skin, red hair, and freckling is associated with high amount of pheomelanin, little amounts of eumelanin. This phenotype is caused by a loss-of-function mutation in the melanocortin 1 receptor (MC1R) gene. However, variations in the MC1R gene sequence only have considerable influence on pigmentation in populations where red hair and extremely fair skin is prevalent. The gene variation’s primary effect is to promote eumelanin synthesis at the expense of pheomelanin synthesis, although this contributes to very little
What Bird is That? according to their usual habitat. The accompanying text included brief notes on distribution, breeding and behaviour. While initial sales were poor, history tells us that Cayley had accurately discerned a market need and successfully responded to it. During WWII sales accelerated and Cayley’s first collection, reprinted time and time again, eventually became a household name among birdwatchers and the book was recognised as an Australian classic. The original sponsorship of "What Bird is That?" proved a great investment for the Gould League, who benefited from the sale of its numerous reprints and revised editions. By 1960, it was rated the