Glycogen phosphorylase the site at which the enzyme binds to glycogen granules before initiating cleavage of terminal glucose molecules. In fact, 70% of dimeric phosphorylase in the cell exists as bound to glycogen granules rather than free floating. The inhibition of glycogen phosphorylase has been proposed as one method for treating type 2 diabetes. Since glucose production in the liver has been shown to increase in type 2 diabetes patients, inhibiting the release of glucose from the liver’s glycogen’s supplies appears to be a valid approach. The cloning of the human liver glycogen phosphorylase (HLGP) revealed a new allosteric binding site near
Campbell's Stores 1858-59, Sands Directory lists the following at Campbell's Wharf: Campbell & Co; Sugar Company's stores; JC Dibbs & Co, commission agents and wharfingers; Robert Nash, storekeeper; WH Eldred, Capt, Chili Flour Co; Chilian Consulate - Consul, WH Eldred. In 1861, it shows: Campbell & Co; Colonial Sugar Refining Co, stores; Peruvian guano stores; George Lloyd & Co stores; Robey & Co's stores; George Lewis custom house officer; and WH Eldred, broker & general agent. In 1863, it shows: 4. Merry Willis and Co, merchants; 3. Henry Fisher & Son, sugar factors; 2. Brown & Co, merchants; 1. EM Sayers &