Progesterone and is responsible for approximately 70% of cytochrome P450-mediated progesterone metabolism. Other routes include 6α-, 16α-, and 16β-hydroxylation. However, treatment of women with ketoconazole, a strong CYP3A4 inhibitor, had minimal effects on progesterone levels, producing only a slight and non-significant increase, and this suggests that cytochrome P450 enzymes play only a small role in progesterone metabolism. In women, progesterone levels are relatively low during the preovulatory phase of the menstrual cycle, rise after ovulation, and are elevated during the luteal phase, as shown in diagram below. Progesterone levels tend to be less than 2 ng/mL prior to ovulation, and greater
Half the Sky and when seen by patriarchal husbands and affected wives can change household dynamics. Another solution is sponsored by Always, Always provides feminine care products to school girls so that they do not miss school during their menstrual cycle, which often happens because they feel ashamed. The final and probably most empowering solution is an education. Allowing girls to attend school and go beyond elementary school can truly help women advance in developing countries. Carolyn See, a book critic from "The Washington Post", said in her review: "'Half the Sky' is a call to arms, a call for help, a call