Tendon the presence of denatured collagen are factors that are believed to cause weakening of the tendon ECM and an increase in the potential for another rupture to occur. In response to repeated mechanical loading or injury, cytokines may be released by tenocytes and can induce the release of MMPs, causing degradation of the ECM and leading to recurring injury and chronic tendinopathies. A variety of other molecules are involved in tendon repair and regeneration. There are five growth factors that have been shown to be significantly upregulated and active during tendon healing: insulin-like growth factor 1 (IGF-I), platelet-derived growth factor
Inelastic neutron scattering Inelastic neutron scattering Inelastic neutron scattering is an experimental technique commonly used in condensed matter research to study atomic and molecular motion as well as magnetic and crystal field excitations. It distinguishes itself from other neutron scattering techniques by resolving the change in kinetic energy that occurs when the collision between neutrons and the sample is an inelastic one. Results are generally communicated as the dynamic structure factor (also called inelastic scattering law) formula_1, sometimes also as the dynamic susceptibility formula_2 where the scattering vector formula_3 is the difference between incoming and outgoing wave vector, and "formula_4" is the energy