The body in traditional Chinese medicine organs in the body. (1)The Liver, a Yin organ, influences emotional flexibility and the flow of energy on a cellular level. The organ has a strong impact on the efficiency and effectiveness of the immune system along with storing the body’s blood, a physical manifestation of one’s true self. The Liver rules one’s direction, vision, sense of self-purpose and opens into the eyes. Last, the Liver absorbs what is not digested and regulates blood sugar. Imbalance in the Liver can lead to great problems. Moodiness, anger, pain, poor self-esteem, lack of direction, addiction, and indecision are all associated with the
Glycogen synthase protein phosphatase 1 (PP1), which activates glycogen synthase via dephosphorylation. PP1 is targeted to the glycogen pellet by four targeting subunits, G, G, PTG and R6. These regulatory enzymes are regulated by insulin and glucagon signaling pathways. Mutations in the "GYS1" gene are associated with glycogen storage disease type 0. In humans, defects in the tight control of glucose uptake and utilization are also associated with diabetes and hyperglycemia. Patients with type 2 diabetes normally exhibit low glycogen storage levels because of impairments in insulin-stimulated glycogen synthesis and suppression of glycogenolysis. Insulin stimulates glycogen synthase by inhibiting glycogen synthase kinases