Sickle cell disease other genetic diseases) among African Americans compared to West Africans. Another factor that limits the spread of sickle cell genes in North America is the relative absence of polygamy, which allows affected males to continue to produce many children with multiple partners. The loss of red blood cell elasticity is central to the pathophysiology of sickle cell disease. Normal red blood cells are quite elastic, which allows the cells to deform to pass through capillaries. In sickle cell disease, low oxygen tension promotes red blood cell sickling and repeated episodes of sickling damage the cell membrane and decrease the cell's
Under a Blood Red Sky Under a Blood Red Sky Under a Blood Red Sky is a live album by Irish rock band U2, produced by Jimmy Iovine and released on 21 November 1983. Along with its companion concert film, "", the release helped establish U2's reputation globally as a live act. The album consists of live recordings from three shows on the band's War Tour, from Colorado and Boston in the US and from Germany. An accompanying concert video entitled "U2 Live at Red Rocks: Under a Blood Red Sky" was released the following year. The film was recorded entirely at the outdoor Red