Sinoatrial node rate, and increasing heart rate. An increase in heart rate is known as positive chronotropy. The parasympathetic nerves supplying the SA node (in particular the Vagus nerves) originate in the brain. These nerves release a neurotransmitter called acetylcholine (ACh). ACh binds to a receptor called an M2 muscarinic receptor, located on the SA node membrane. Activation of this M2 receptor, then activates a protein called a G-protein (in particular G protein, i for inhibitory). Activation of this G-protein, blocks the cAMP pathway, reducing its effects, therefore inhibiting sympathetic activity and slowing action potential production. As well as this, the G-protein
Node (circuits) Dots used to mark nodes on a circuit diagram are sometimes referred to as "meatballs". Node (circuits) In electrical engineering, a node is any point on a circuit where the terminals of two or more circuit elements meet. In circuit diagrams, connections are ideal wires with zero resistance, so a node may consist of the entire section of wire between elements, not just a single point. According to Ohm's law, "V = IR", the voltage across any two points of a node with negligible resistance is showing that the voltage at every point of a node is the same. However,