Nav1.5 kb. The gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5’ untranslated region (5’UTR) and exon 28 the 3’ untranslated region (3’UTR) of the RNA. SCN5A is part of a family of 10 genes that encode different types of sodium channels, i.e. brain-type (Na1.1, Na1.2, Na1.3, Na1.6), neuronal channels (Na1.7, Na1.8 and Na1.9), skeletal muscle channels (Na1.4) and the cardiac sodium channel Na1.5. SCN5A is mainly expressed in the heart, where expression is abundant in working myocardium and conduction tissue. In contrast, expression is low in the sinoatrial node and atrioventricular node.
Node (Well of Echoes) or node-drainers that drain the node of the field and render anything that draws power from it useless. Mancers who cannot draw from a distat node's field must rely on charged crystals, while clankers, constructs and any other devices of the Art will not work. There are also rare places called anti-nodes, where the Art does not work or is at least greatly reduced. Node (Well of Echoes) Nodes are fictional, naturally occurring phenomena in Ian Irvine’s "The Three Worlds Cycle" of novels. They often occur in places where there is a significant landmark, such as on a hill or