Nav1.5 kb. The gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5’ untranslated region (5’UTR) and exon 28 the 3’ untranslated region (3’UTR) of the RNA. SCN5A is part of a family of 10 genes that encode different types of sodium channels, i.e. brain-type (Na1.1, Na1.2, Na1.3, Na1.6), neuronal channels (Na1.7, Na1.8 and Na1.9), skeletal muscle channels (Na1.4) and the cardiac sodium channel Na1.5. SCN5A is mainly expressed in the heart, where expression is abundant in working myocardium and conduction tissue. In contrast, expression is low in the sinoatrial node and atrioventricular node.
Longitude of the ascending node it is not possible to tell which node is ascending and which is descending. In this case the orbital parameter which is recorded is the longitude of the node, Ω, which is the longitude of whichever node has a longitude between 0 and 180 degrees. In astrodynamics, the longitude of the ascending node can be calculated from the specific relative angular momentum vector h as follows: Here, n=<"n", "n", "n"> is a vector pointing towards the ascending node. The reference plane is assumed to be the "xy"-plane, and the origin of longitude is taken to be the positive "x"-axis. k