Pituitary gland types of cells can be differentiated. The posterior lobe develops as an extension of the hypothalamus. The posterior pituitary hormones are synthesized by cell bodies in the hypothalamus. The magnocellular neurosecretory cells, of the supraoptic and paraventricular nuclei located in the hypothalamus, project axons down the infundibulum to terminals in the posterior pituitary. This simple arrangement differs sharply from that of the adjacent anterior pituitary, which does not develop from the hypothalamus. The release of pituitary hormones by both the anterior and posterior lobes is under the control of the hypothalamus, albeit in different ways. The anterior pituitary synthesizes and
Pituitary pars intermedia dysfunction increased predisposition to infection usually take between 30 days and 1 year to improve. Cyproheptadine may be added to the treatment regime in horses that are inadequately responding to pergolide, but is usually only used in horses with advanced PPID on high doses of pergolide. Pituitary pars intermedia dysfunction Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, and is classically associated with the formation of a long, wavy coat (hirsutism) and chronic laminitis. Unlike the human and canine forms of Cushing's