Menstrual cycle enhanced during the luteal phases of the menstrual cycle. This is due to the higher metabolic demand during this phase. In particular, women tend to show a cravings for chocolate, with higher cravings during the luteal phase. Females with premenstrual syndrome (PMS) report changes in appetite across the menstrual cycle more than non-sufferers of PMS, possibly due to their oversensitivity to changes in hormone levels. In women with PMS, food intake is higher in the luteal phase than follicular. The remaining symptoms of PMS, including mood changes and physical symptoms, also occur during the luteal phase. No difference for preference
Progesterone (medication) are up to 100-fold higher than during normal menstrual cycling, although levels increase gradually over the course of pregnancy. Oral dosages of progesterone of as high as 3,600 mg/day have been assessed in clinical trials, with the main side effect being sedation. There is a case report of progesterone misuse with an oral dosage of 6,400 mg per day. Administration of as much as 1,000 mg progesterone by intramuscular injection in humans was uneventful in terms of toxicity, but did induce extreme sedation and somnolence accompanied by nearly unarousable sleep, though the individuals were still able to be awakened with