Antibiotic penicillin led to renewed interest in the search for antibiotic compounds with similar efficacy and safety. For their successful development of penicillin, which Fleming had accidentally discovered but could not develop himself, as a therapeutic drug, Chain and Florey shared the 1945 Nobel Prize in Medicine with Fleming. Florey credited Rene Dubos with pioneering the approach of deliberately and systematically searching for antibacterial compounds, which had led to the discovery of gramicidin and had revived Florey's research in penicillin. In 1939, coinciding with the start of World War II, Dubos had reported the discovery of the first naturally derived antibiotic,
Who I Was Born to Be to Be" was composed by Johan Fransson, Tim Larsson, and Tobias Lundgren. Among her most notable performances of "Who I Was Born to Be", Boyle's first live performance of this song was on 7 December 2009 in London before an audience for the taping of her television special "". "Who I Was Born to Be" was used as the theme song for the anime "Welcome to the Space Show" which was released in 2010. Boyle performed the song on The Oprah Winfrey Show in Chicago on 19 January 2010. On 10 July 2011 she performed it in front of a