Tendon and degeneration or weakening of the tendons, which may eventually lead to tendon rupture. Tendinopathies can be caused by a number of factors relating to the tendon extracellular matrix (ECM), and their classification has been difficult because their symptoms and histopathology often are similar. The first category of tendinopathy is paratenonitis, which refers to inflammation of the paratenon, or paratendinous sheet located between the tendon and its sheath. Tendinosis refers to non-inflammatory injury to the tendon at the cellular level. The degradation is caused by damage to collagen, cells, and the vascular components of the tendon, and is known to
Golgi tendon reflex relaxation before the tendon tension becomes high enough to cause damage. First, as a load is placed on the muscle, the afferent neuron from the Golgi tendon organ fires into the central nervous system. Second, the motor neuron from the spinal cord is inhibited via an IPSP and muscle relaxes. The stretch reflex operates as a feedback mechanism to control muscle length by causing muscle contraction. In contrast, the tendon reflex operates as a feedback mechanism to control muscle tension by causing muscle relaxation before muscle force becomes so great that tendons might be torn. Although the tendon reflex is