Work of breathing Work of breathing Work of breathing (WOB) is the energy expended to inhale and exhale a breathing gas. It is usually expressed as work per unit volume, for example, joules/litre, or as a work rate (power), such as joules/min or equivalent units, as it is not particularly useful without a reference to volume or time. It can be calculated in terms of the pulmonary pressure multiplied by the change in pulmonary volume, or in terms of the oxygen consumption attributable to breathing. In a normal resting state the work of breathing constitutes about 5% of the total body oxygen consumption.
The Logic of Scientific Discovery The Logic of Scientific Discovery The Logic of Scientific Discovery is a 1959 book about the philosophy of science by Karl Popper. Popper rewrote his book in English from the 1934 German original, titled "Logik der Forschung. Zur Erkenntnistheorie der modernen Naturwissenschaft", which literally translates as, "Logic of Research: On the Epistemology of Modern Natural Science"'. Popper argues that science should adopt a methodology based on falsifiability, because no number of experiments can ever prove a theory, but a reproducible experiment or observation can refute one. According to Popper: "non-reproducible single occurrences are of no significance to science. Thus a