Tendon the presence of denatured collagen are factors that are believed to cause weakening of the tendon ECM and an increase in the potential for another rupture to occur. In response to repeated mechanical loading or injury, cytokines may be released by tenocytes and can induce the release of MMPs, causing degradation of the ECM and leading to recurring injury and chronic tendinopathies. A variety of other molecules are involved in tendon repair and regeneration. There are five growth factors that have been shown to be significantly upregulated and active during tendon healing: insulin-like growth factor 1 (IGF-I), platelet-derived growth factor
Tendon-driven robot larger than Roboy and includes 160 pulley-like muscles and aluminum bones that allow it to perform simple bends and poses. Bionic Robotics offered BioRob, a tendon-driven robotic arm for industrial use. It has a flexible mechanical structure that allows it to pick up heavy payloads even though it weighs much less than the conventional robotic arm that the company also makes. BioRob’s light weight and flexible design is claimed to offer greater safety for use around human workers. Caliper is a framework for the simulation of tendon-driven robots. It consists of a generic physics simulator capable of utilizing computer-aided design