Thioglycolic acid corresponding disulfide (2-[(carboxymethyl)disulfanyl]acetic acid or dithiodiglycolic acid): Thioglycolic acid, usually as its dianion, forms complexes with metal ions. Such complexes have been used for the detection of iron, molybdenum, silver, and tin. Thioglycolic acid reacts with diethyl acetylmalonate to form acetylmercaptoacetic acid and diethyl malonate, the reducing agent in conversion of Fe(III) to Fe(II). Scientist David R. Goddard, in the early 1930s, identified TGA as a useful reagent for reducing the disulfide bonds in proteins, including keratin (hair protein), while studying why protease enzymes could not easily digest hair, nails, feathers, and such. He realized that while the disulfide bonds,
Hair removal been used in attempts to eradicate lice or to minimize body odor due to accumulation of odor-causing micro-organisms in hair. Some people with trichiasis find it medically necessary to remove ingrown eyelashes. Shaving against the grain can often cause ingrown hairs. Many forms of cancer require chemotherapy, which often causes severe and irregular hair loss. For this reason, it is common for cancer patients to shave their heads even before starting chemotherapy. In extreme situations people may need to remove all body hair to prevent or combat infestation by lice, fleas and other parasites. Such a practice was used, for