Multiple endocrine neoplasia type 1 ATR. The exact function of MEN1 and the protein, menin, produced by this gene is not known, but following the inheritance rules of the "two-hit hypothesis" indicates that it acts as a tumor suppressor. In a diagnostic workup individuals with a combination of endocrine neoplasias suggestive of the "MEN1 syndrome" are recommended to have a mutational analysis of the MEN1 gene if additional diagnostic criteria are sufficiently met, mainly including: Multiple endocrine neoplasia or MEN is part of a group of disorders that affect the body's network of hormone-producing glands (the endocrine system). Hormones are chemical messengers that travel through
Building control body Building control body A building control body is an organisation authorised to control building work that is subject to the Building Regulations in England and Wales (similar systems are provided in Northern Ireland, and in Scotland where the term 'building standards' is used). Building control roles are exercised by officers in local authorities and by private sector Approved Inspectors. The title "Building control officer" (BCO) (also known as a "building inspector" or a "building control surveyor") is used predominantly by local authorities, which confer the title of "officer" to many staff who have regulatory, supervision or enforcement roles. Private sector