Asphyxiant gas can smell the odorants, and assigning a different smell to each gas may be impractical. Another difficulty is that most odorants (e.g., the thiols) are chemically reactive. This is not a problem with natural gas intended to be burned as fuel, which is routinely odorized, but a major use of asphyxiants such as nitrogen, helium, argon and krypton is to protect reactive materials from the atmosphere. The dangers of excess concentrations of nontoxic gases has been recognized for centuries within the mining industry. The concept of black damp (or "stythe") reflects an understanding that certain gaseous mixtures could lead to
Reducing atmosphere had a reducing atmosphere, along with Mars and Venus. This would have proven to be a good environment for "Cyanobacteria" to evolve the first photosynthetic metabolic pathways which gradually increased the oxygen portion of the atmosphere, changing it to what is known as an oxidizing atmosphere. With increased levels of oxygen, the evolution of the more efficient aerobic respiration might have been enabled, allowing animal life to evolve and thrive. Though most scientists conceive of the early atmosphere as reducing, a 2011 article in "Nature" found that cerium oxidation in zircon—which comprises the oldest rocks on Earth at roughly 4.4