Apparent mineralocorticoid excess syndrome cases recorded worldwide. Liquorice consumption may also cause a temporary form of AME due to its ability to block 11β-hydroxysteroid dehydrogenase type 2, in turn causing increased levels of cortisol. Cessation of licorice consumption will reverse this form of AME. Apparent mineralocorticoid excess syndrome Apparent mineralocorticoid excess (AME) is an autosomal recessive disorder causing hypertension (high blood pressure) and hypokalemia (abnormally low levels of potassium). It was found by Dr Maria I. New at Weil Cornell Hospital in New York City. It results from mutations in the "HSD11B2" gene, which encodes the kidney isozyme of 11β-hydroxysteroid dehydrogenase type 2. In
Water organ aspiration (using the Bernoulli effect) into the main pipe from a side-pipe holding its top above the water source. Both water and air arrive together in the camera aeolis (wind chamber). Here, water and air separate and the compressed air is driven into a wind-trunk on top of the camera aeolis, to blow the organ pipes. Two perforated ‘splash plates’ or ‘diaphragms’ prevent water spray from getting into the organ pipes. The water, having been separated from the air, leaves the camera aeolis at the same rate as it enters. It then drives a water wheel, which in turn drives