Nucleated red blood cell in the normal development of a normoblast. A megaloblast is an unusually large erythroblast that can be associated with vitamin B deficiency (caused by pernicious anemia or dietary insufficiency), folic acid deficiency, or both (such anemias are collectively called megaloblastic anemias). This kind of anemia leads to macrocytes (abnormally large red cells) and the condition called macrocytosis. The cause of this cellular gigantism is an impairment in DNA replication that delays nuclear maturation and cell division. Because RNA and cytoplasmic elements are synthesized at a constant rate despite the cells' impaired DNA synthesis, the cells show nuclear-cytoplasmic asynchrony. NRB's can
The Blood Cell characterisation perfectly". The audio addition to the book was released on 13 November 2014, read by Colin McFarlane who played General Austin Pierce in "" and guest starred in the "Doctor Who" episodes "Under the Lake" and "Before the Flood" as Moran. This was the first new series audio to be released since AudioGo went into administration in 2013. The Blood Cell The Blood Cell is a BBC Books original novel written by James Goss and based on the long-running British science fiction television series "Doctor Who". It features the Twelfth Doctor and Clara Oswald. The book was released on