Sickle cell nephropathy Sickle cell nephropathy Sickle cell nephropathy is a type of nephropathy associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla, coupled with the slow blood flow in the vasa recta, favors sickling of red blood cells, with resultant local infarction (papillary necrosis). Functional tubule defects in patients with sickle cell disease are likely the result of partial ischemic injury to the renal tubules. Also the sickle cell disease in young patients is characterized by renal hyperperfusion,
Blood red wound, and it does not change color upon exposure to air. The color "blood red", therefore, covers both these states: the darker deoxygenated color and the brighter oxygenated one. Also, dried blood often has a darker, rust-colored quality: all dried blood has been oxygenated and then desiccated, causing the cells within it to die. This blood is often darker than either shade of red that can be seen in fresh blood. In the RGB color spectrum blood red often consists only of the color red, with no green or blue component; in the CYMK color model blood red has no