Organ procurement of kidneys is a relatively widespread practice. For the heart normothermic preservation has been used in which the heart is provided with warm oxygenated blood and so continues to beat ex-vivo during its preservation. This technique has also been applied to lungs and led to the emergence of donor lung reconditioning centres in North America. For the liver, hypothermic and normothermic techniques are being used with evidence to suggest that both may be beneficial . The HOPE (HIV Organ Policy Equity) Act allows for clinical research on organ transplantation from HIV+ donors to HIV+ recipients. The Act was passed by
Subcommissural organ neuronal cell bodies within the subcommissural organ, although the specialized cells receive some innervation from outside neurons. Ependymal cells secrete high molecular mass glycoproteins into the cerebrospinal fluid, in which the bulk of them condense to form a filamentous structure named Reissner’s fiber. The subcommissural organ/Reissner’s fiber complex is thought to be involved in the reabsorption and circulation of the cerebrospinal fluid, and with functions related to electrolyte and water balance. One of the proteins secreted by the subcommissural organ, and which is present in Reissner’s fiber, is spondin. SCO-spondin is a “giant” (5000 amino acids) glycoprotein (thrombospondin superfamily) found