Protein or the physical region of the protein that participates in chemical catalysis. In solution proteins also undergo variation in structure through thermal vibration and the collision with other molecules. Proteins can be informally divided into three main classes, which correlate with typical tertiary structures: globular proteins, fibrous proteins, and membrane proteins. Almost all globular proteins are soluble and many are enzymes. Fibrous proteins are often structural, such as collagen, the major component of connective tissue, or keratin, the protein component of hair and nails. Membrane proteins often serve as receptors or provide channels for polar or charged molecules to pass
Cleft lip and palate transmembrane protein 1 may belong to a new gene family. This family also contains the "Homo sapiens" cisplatin resistance related protein CRR9p which is associated with CDDP-induced apoptosis. Cleft lip and palate transmembrane protein 1 Cleft lip and palate transmembrane protein 1 is a protein that in humans is encoded by the "CLPTM1" gene. It belongs to a family of several eukaryotic cleft lip and palate transmembrane protein 1 sequences. Cleft lip with or without cleft palate is a common birth defect that is genetically complex. The nonsyndromic forms have been studied genetically using linkage and candidate-gene association studies with only partial success