Sexual differentiation absence of the genes that generate male genitalia do not single-handedly lead to a female brain. The male brain requires more hormones, such as testosterone, in order to properly differentiate. These hormones are released due to a gene expressed during embryonic development. Sexual differentiation Sexual differentiation is the process of development of the differences between males and females from an undifferentiated zygote. As male and female individuals develop from zygotes into fetuses, into infants, children, adolescents, and eventually into adults, sex and gender differences at many levels develop: genes, chromosomes, gonads, hormones, anatomy, and psyche. Sex differences range greatly and
Familial male-limited precocious puberty combination of the androgen receptor antagonist bicalutamide and the aromatase inhibitor anastrozole may be used. Familial male-limited precocious puberty Familial male-limited precocious puberty, often abbreviated as FMPP, also known as familial sexual precocity or gonadotropin-independent testotoxicosis, is a form of gonadotropin-independent precocious puberty in which boys experience early onset and progression of puberty. Signs of puberty can develop as early as an age of 1 year. The spinal length in boys may be short due to a rapid advance in epiphyseal maturation. It is an autosomal dominant condition with a mutation of the luteinizing hormone (LH) receptor. Treatment is with