Alpha thalassemia abnormal morphogenesis Alpha thalassemia abnormal morphogenesis Alpha Thalassemia-Abnormal Morphogensis is a group of blood disorders that affect the way the body makes hemoglobin. Hemoglobin is a protein found in red blood cells that carries oxygen throughout the body. It's made up of alpha globin and beta globin. Normally each person has four genes for alpha globin, Alpha thalassemia happens when one or more of the genes that control the making of alpha globin is absent or defective. It can cause anemia ranging from mild to severe. Also causing Genital abnormalities and terminal transverse limb defectiveness which is why it is called abnormal
Blood volume Blood volume Blood volume is the volume of blood (both red blood cells and plasma) in the circulatory system of any individual. A typical adult has a blood volume of approximately 5 liters, with females and males having approximately the same blood volume. Blood volume is regulated by the kidneys. Blood volume (BV) can be calculated given the hematocrit (HC; the fraction of blood that is red blood cells) and plasma volume (PV), with the hematocrit being regulated via the blood oxygen content regulator: Blood volume measurement may be used in people with congestive heart failure, chronic hypertension, renal failure