Sinoatrial node therefore cause ischaemia and cell death in the SA node. This can disrupt the electrical pacemaker function of the SA node, and can result in sick sinus syndrome. If the SA node does not function, or the impulse generated in the SA node is blocked before it travels down the electrical conduction system, a group of cells further down the heart will become its pacemaker. The sinoatrial node was first discovered by a young medical student, Martin Flack, in the heart of a mole, whilst his mentor, Sir Arthur Keith, was on a bicycle ride with his wife. They made
Node graph architecture Node graph architecture Node graph architecture is a type of software design which builds around modular node components which can be connected to form a graph. Often the software's underlying node graph architecture is also exposed to the end user as a two-dimensional visualization of the node graph. The node graph architecture is popular in the film and computer games industry. There are often many different node types participating in the node graph. For example, in the Nuke Manual they list hundreds of nodes. Each node type performs one specific task. For example, Nuke's Merge node produces an output image