Development of the digestive system As a result of the cephalocaudal and lateral folding of the embryo, a portion of the endoderm-lined yolk sac cavity is incorporated into the embryo to form the primitive gut. In the cephalic and caudal parts of the embryo, the primitive gut forms a tube, the foregut and hindgut, respectively. The middle part, the midgut, remains temporally connected to the yolk sac by means of the vitelline duct. The foregut gives rise to the esophagus, the trachea, lung buds, the stomach, and the duodenum proximal to the entrance of the bile duct. In addition, the liver, pancreas, and biliary apparatus
Chronic airway-digestive inflammatory disease Chronic airway-digestive inflammatory disease Sinus disease, allergies, and asthma have been shown to be intimately related through recent research. Moreover, gastroesophageal reflux disease (GERD), laryngopharyngeal reflux disease (LPRD) and/or snoring or sleep apnea are often present as well. “Chronic Airway-Digestive Inflammatory Disease” (CAID) is a phrase which has been coined by Dr. Jordan S. Josephson, M.D., F.A.C.S. and Dr. Jens Ponikeau, M.D. to describe this very complex set of problems which are caused by inflammation. This term was first described in a book entitled Sinus Relief Now .CAID directly affects the upper respiratory system (the nose and the sinuses), the