Organ donation rabbinic authorities believe that organ donation may be mandatory, whereas a minority opinion considers any donation of a live organ as forbidden. The demand for organs significantly surpasses the number of donors everywhere in the world. There are more potential recipients on organ donation waiting lists than organ donors. In particular, due to significant advances in dialysis techniques, patients suffering from end-stage renal disease (ESRD) can survive longer than ever before. Because these patients don't die as quickly as they used to, and as kidney failure increases with the rising age and prevalence of high blood pressure and diabetes in
Base excess data. The term and concept of base excess were first introduced by Poul Astrup and Ole Siggaard-Andersen in 1958. Base excess can be estimated from the bicarbonate concentration ([HCO]) and pH by the equation: formula_1 with units of mEq/L. The same can be alternatively expressed as formula_2 Calculations are based on the Henderson-Hasselbalch equation: Ultimately the end result is: Base excess beyond the reference range indicates Blood pH is determined by both a metabolic component, measured by base excess, and a respiratory component, measured by PaCO (partial pressure of carbon dioxide). Often a disturbance in one triggers a partial compensation