Hypoadrenocorticism in dogs Hypoadrenocorticism in dogs Hypoadrenocorticism in dogs, or, as it is known in people, Addison's disease, is an endocrine system disorder that occurs when the adrenal glands fail to produce enough hormones for normal function. The adrenal glands secrete glucocorticoids such as cortisol and mineralocorticoids such as aldosterone; when proper amounts of these are not produced, the metabolic and electrolyte balance is upset. Mineralocorticoids control the amount of potassium, salt and water in the body. Hypoadrenocorticism is fatal if left untreated. All causes for hypoadrenocorticism are not yet known. The usual causes are genetic, often related to autoimmune disorders, where the
Toxic Substances Control Act of 1976 later explained during a 1975 Congressional Testimony, "While some authority exists to control the production of certain categories of toxic substances, such as pesticides, drugs, and food additives, most existing Federal authorities are designed to prevent harmful exposure only after the substances have been introduced into production." In Order to adequately regulate what chemicals should enter the environment, CEQ recommended that the government create a more comprehensive chemical policy to identify and control the chemicals that are manufactured, produced, and used in the U.S economy. Specifically, CEQ recommended that TSCA strengthen government oversight by requiring the following measures: First, manufacturers