Exercise physiology loss of integrity to the blood brain barrier. Hyperthermia also can lower cerebral blood flow, and raise brain temperature. Researchers once attributed fatigue to a build-up of lactic acid in muscles. However, this is no longer believed. Rather, lactate may stop muscle fatigue by keeping muscles fully responding to nerve signals. The available oxygen and energy supply, and disturbances of muscle ion homeostasis are the main factor determining exercise performance, at least during brief very intense exercise. Each muscle contraction involves an action potential that activates voltage sensors, and so releases Ca ions from the muscle fibre’s sarcoplasmic reticulum. The
The Debt (2014 film) family appears normal and happy. Her loving husband dotes on her and their beautiful daughter. But in her heart lies a secret that eats at her soul like a malignant cancer, causing irritability and unpredictable outbursts that make her a stranger in her own home. Shame and guilt from wartime experiences fill every waking and sleeping moment. Desperate, she decides to take an extreme action to escape her past. Instead, she comes face-to-face with a surprising truth." The Debt (2014 film) The Debt is a short film produced and directed by Mahmoud Shoolizadeh, that has participated in several international film