Blood sugar regulation cells in the pancreatic islets are among the most well understood and important. If the blood glucose level falls to dangerous levels (as during very heavy exercise or lack of food for extended periods), the alpha cells of the pancreas release glucagon, a hormone whose effects on liver cells act to increase blood glucose levels. They convert glycogen into glucose (this process is called glycogenolysis). The glucose is released into the bloodstream, increasing blood sugar. Hypoglycemia, the state of having low blood sugar, is treated by restoring the blood glucose level to normal by the ingestion or administration of dextrose
Fifty nine Particulars laid down for the Regulating of things Fifty nine Particulars laid down for the Regulating of things Fifty nine Particulars laid down for the Regulating things is an English pamphlet that scholars attribute to publication in 1659 by George Fox, founding preacher of Quakerism. It calls for a long list of social reforms, and purports to have been sent to members of Parliament, which ignored it. The pamphlet was never reprinted, probably due to its politically assertive nature and the desire of post-Restoration Quakers to make themselves respectable and non-threatening to the established authorities, who ever since the execution of Charles I had been concerned about political