Transgender hormone therapy (male-to-female) medical professional. Inducers of CYP3A4 and other cytochrome P450 enzymes can reduce the effects of MTF HRT. A variety of different sex-hormonal medications are used in feminizing hormone therapy for transgender women. These include estrogens to induce feminization and suppress testosterone levels; antiandrogens such as androgen receptor antagonists, antigonadotropins, GnRH modulators, and 5α-reductase inhibitors to further oppose the effects of androgens like testosterone; and progestogens for various possible though uncertain benefits. Estrogens are the major sex hormones in women, and are responsible for the development and maintenance of feminine secondary sexual characteristics, such as breasts, wide hips, and a feminine
Trophic hormone causes hyperplasia of enterochromaffin cells which may transform into carcinoid tumors. Trophic hormone Trophic hormone is a hormone that has a growth effect, hyperplasia or hypertrophy, on the tissue it is stimulating. The term "trophic" is from Ancient Greek τροφικός ("trophikós") meaning "pertaining to food or nourishment", here used to mean "growth"; this is the same origin as "atrophy." This should not be confused with "tropic," as in the similar-sounding tropic hormone – the words and concepts are both unrelated. A key example of this is thyroid-stimulating hormone stimulating the thyroid; excess thyroid-stimulating hormone can create a goitre. Trophic hormones