Max Perutz the onset of Huntington disease is related to the number of glutamine repeats as they bind to form what he called a polar zipper. During the early 1950s, while Watson and Crick were determining the structure of deoxyribonucleic acid (DNA), they made use of unpublished X-ray diffraction images taken by Rosalind Franklin, shown at meetings and shared with them by Maurice Wilkins, and of Franklin's preliminary account of her detailed analysis of the X-ray images included in an unpublished 1952 progress report for the King's College laboratory of Sir John Randall. Randall and others eventually criticised the manner in which
DNA coworkers Colin MacLeod and Maclyn McCarty, identified DNA as the transforming principle, supporting Griffith's suggestion (Avery–MacLeod–McCarty experiment). DNA's role in heredity was confirmed in 1952 when Alfred Hershey and Martha Chase in the Hershey–Chase experiment showed that DNA is the genetic material of the T2 phage. Late in 1951, Francis Crick started working with James Watson at the Cavendish Laboratory within the University of Cambridge. In 1953, Watson and Crick suggested what is now accepted as the first correct double-helix model of DNA structure in the journal "Nature". Their double-helix, molecular model of DNA was then based on one X-ray