Leg hair follicle it pushed older cells out and that is what becomes the leg hair. After the older cells become hard and leave the follicle, they form a hair shaft. The hair shaft is mostly made up of dead tissue and a protein that is known as keratin. It is said that hair growth occurs during the "growing" phase of the follicle, and then retained as dead club hair during the "resting" phase. The old club hair might be lost within the following "growing" phase. Men are seen to be much hairier than women, even though men and women are much
Microphthalmia-associated transcription factor MITF protein. The new MITF protein is unable to bind to DNA and melanocyte development and subsequently melanin production is altered. A reduced number of melanocytes can lead to hearing loss, and decreased melanin production can account for the light skin and hair color that make Tietz syndrome so noticeable. Melanocytes are commonly known as cells that are responsible for producing the pigment melanin which gives coloration to the hair, skin, and nails. The exact mechanisms of how exactly melanocytes become cancerous are relatively unclear, but there is ongoing research to gain more information about the process. For example, it