Basal metabolic rate be elevated in stress, illness, and diabetes. Menopause may also affect metabolism. Heart rate is determined by the medulla oblongata and part of the pons, two organs located inferior to the hypothalamus on the brain stem. Heart rate is important for basal metabolic rate and resting metabolic rate because it drives the blood supply, stimulating the Krebs cycle. During exercise that achieves the anaerobic threshold, it is possible to deliver substrates that are desired for optimal energy utilization. The anaerobic threshold is defined as the energy utilization level of heart rate exertion that occurs without oxygen during a standardized test
The Centre of the Heart although multiple promotional singles were issued which titled the track "The Centre of the Heart (Is a Suburb to the Brain)". Non-album track "Entering Your Heart" appears as a b-side on most editions of the single. An extended version of the b-side, containing an extra verse, also appeared on Japanese editions of "Room Service". A maxi single was also issued, containing four remixes of the song by Swedish DJ StoneBridge, as well as an additional remix created by Jens Bjurman and Per Kalenius, titled the 'Yoga Remix'. The StoneBridge Club Mix was featured in several "Dance Dance Revolution" video games