Endocrine gland hormones at target cells "Permissiveness" is the situation in which a hormone cannot exert its full effects without the presence of another hormone. "Synergism" occurs when two or more hormones produce the same effects in a target cell and their results are amplified. "Antagonism" occurs when a hormone opposes or reverses the effect of another hormone. The endocrine glands belong to the body's control system. The hormones which they produce help to regulate the functions of cells and tissues throughout the body. Endocrine organs are activated to release their hormones by humoral, neural or hormonal stimuli. Negative feedback is important
Endocrine disruptor was by Theo Colborn in 1993. In this paper, she stated that environmental chemicals disrupt the development of the endocrine system, and that effects of exposure during development are often permanent. Although the endocrine disruption has been disputed by some, work sessions from 1992 to 1999 have generated consensus statements from scientists regarding the hazard from endocrine disruptors, particularly in wildlife and also in humans. The Endocrine Society released a scientific statement outlining mechanisms and effects of endocrine disruptors on “male and female reproduction, breast development and cancer, prostate cancer, neuroendocrinology, thyroid, metabolism and obesity, and cardiovascular endocrinology,” and showing