State microbe is noteworthy because it is: the first significant antibiotic discovered after penicillin; the first systemic antibiotic discovered in America; the first antibiotic active against tuberculosis; first-line treatment for plague. Moreover, New Jersey was the home of Selman Waksman, who was awarded the Nobel Prize in Physiology or Medicine for his systematic studies of antibiotic production by "S. griseus" and other soil microbes. On May 15, 2017, Senate Bill 3190 (S3190) was introduced by Senator Samuel D. Thompson (R-12); the bill designates "Streptomyces griseus" as the New Jersey State Microbe, to be added to the state's other state symbols. On June
Quinolone antibiotic 4-quinolones, are gemifloxacin (Factive) and trovafloxacin (Trovan) (removed from clinical use). In development. Quinolones have been widely used in animal husbandry, and several agents have veterinary-specific applications. Quinolone antibiotic A quinolone antibiotic is any member of a large group of broad-spectrum bactericides that share a bicyclic core structure related to the compound 4-quinolone. They are used in human and veterinary medicine to treat bacterial infections, as well as in animal husbandry. Nearly all quinolone antibiotics in use are fluoroquinolones, which contain a fluorine atom in their chemical structure and are effective against both Gram-negative and Gram-positive bacteria. One example is