Helicine arteries of penis Helicine arteries of penis The helicine arteries of penis are arteries in the penis. They are found in the corpora cavernosa penis. They are involved in the process of erection. On entering the cavernous structure from the deep artery of the penis the arteries divide into branches, which are supported and enclosed by the trabeculae. Some of these arteries end in a capillary net-work, the branches of which open directly into the cavernous spaces; others assume a tendril-like appearance, and form convoluted and somewhat dilated vessels, which were named by Rosenmüller "helicine arteries". These arteries have two unique features: an
Helicine arteries of penis in increased levels of cyclic guanosine monophosphate (cGMP). cGMP in turn triggers relaxation of the smooth muscle and results in dilation of blood vessels. This signal is terminated when cGMP is broken down by the enzyme cGMP specific phosphodiesterase type 5 (PDE5), the enzyme that is targeted by sildenafil and other drugs that treat erectile dysfunction. By preventing PDE5 from breaking down cGMP, the effects of NO are amplified and vasodilation occurs, thus resulting in increased penile erection. Helicine arteries of penis The helicine arteries of penis are arteries in the penis. They are found in the corpora cavernosa penis.