Parasympathetic nervous system act in a complementary way increasing or slowing the heart rate. In this context, the vagus nerve acts on sinoatrial node slowing its conduction thus actively modulating vagal tone accordingly. This modulation is mediated by the neurotransmitter acetylcholine and downstream changes to ionic currents and calcium of heart cells. The vagus nerve plays a crucial role in heart rate regulation by modulating the response of sinoatrial node, vagal tone can be quantified by investigating heart rate modulation induced by vagal tone changes. As a general consideration, increased vagal tone (and thus vagal action) is associated with a diminished and more
Node (Well of Echoes) or node-drainers that drain the node of the field and render anything that draws power from it useless. Mancers who cannot draw from a distat node's field must rely on charged crystals, while clankers, constructs and any other devices of the Art will not work. There are also rare places called anti-nodes, where the Art does not work or is at least greatly reduced. Node (Well of Echoes) Nodes are fictional, naturally occurring phenomena in Ian Irvine’s "The Three Worlds Cycle" of novels. They often occur in places where there is a significant landmark, such as on a hill or