Multiple endocrine neoplasia type 1 symptoms. These disorders greatly increase the risk of developing multiple cancerous and noncancerous tumors in glands such as the parathyroid, pituitary, and pancreas. Multiple endocrine neoplasia occurs when tumors are found in at least two of the three main endocrine glands (parathyroid, pituitary, and pancreatico-duodenum). Tumors can also develop in organs and tissues other than endocrine glands. If the tumors become cancerous, some cases can be life-threatening. The disorder affects 1 in 30,000 people. Although many different types of hormone-producing tumors are associated with multiple endocrine neoplasia, tumors of the parathyroid gland, pituitary gland, and pancreas are most frequent in
Ciaccio's glands sometimes called "Wolfring's glands" after Polish ophthalmologist Emilj von Wolfring (1832-1906), who described them during the same time period as did Ciaccio. Another type of accessory lacrimal gland are "Krause's glands", which are smaller, more numerous than "Ciaccio's glands" and are found along the superior and inferior fornices of the conjunctival sac. Ciaccio's glands Ciaccio's glands or Wolfring's glands are small tubular accessory lacrimal glands ("glandulae lacrimales accessoriae") found in the lacrimal caruncle of the eyelid. They are located in the upper border of the tarsus, approximately in the middle between the extremities of the tarsal glands. Sometimes they are