Development of the nervous system in humans optical vesicle (which will eventually become the optic nerve, retina and iris) forms at the basal plate of the prosencephalon. In the fifth week, the alar plate of the prosencephalon expands to form the cerebral hemispheres (the telencephalon). The basal plate becomes the diencephalon. The diencephalon, mesencephalon and rhombencephalon constitute the brain stem of the embryo. It continues to flex at the mesencephalon. The rhombencephalon folds posteriorly, which causes its alar plate to flare and form the fourth ventricle of the brain. The pons and the cerebellum form in the upper part of the rhombencephalon, whilst the medulla oblongata forms
Anterior median fissure of the medulla oblongata join the inferior peduncle. Anterior median fissure of the medulla oblongata The anterior median fissure (ventral or ventromedian fissure) contains a fold of pia mater, and extends along the entire length of the medulla oblongata: It ends at the lower border of the pons in a small triangular expansion, termed the foramen cecum. Its lower part is interrupted by bundles of fibers that cross obliquely from one side to the other, and constitute the pyramidal decussation. Some fibers, termed the anterior external arcuate fibers, emerge from the fissure above this decussation and curve lateralward and upward over the surface of