Glipizide 10 milligrams. Glipizide sensitizes the beta cells of pancreatic islets of Langerhans insulin response, meaning that more insulin is released in response to glucose than would be without glipizide ingestion. Glipizide acts by partially blocking potassium channels among beta cells of pancreatic islets of Langerhans. By blocking potassium channels, the cell depolarizes, which results in the opening of voltage-gated calcium channels. The resulting calcium influx encourages insulin release from beta cells. Glipizide Glipizide is an oral rapid- and short-acting anti-diabetic medication from the sulfonylurea class. It is classified as a second-generation sulfonylurea, which means that it undergoes enterohepatic circulation. Second-generation
Ryan Langerhans RBIs, and 19 stolen bases. In 2000, Langerhans was assigned to the Class-A Advanced Myrtle Beach Pelicans of the Carolina League. He appeared in 116 games with the Pelicans and batted .212 with 14 doubles, 7 triples, 6 home runs, 37 RBIs, and 25 stolen bases. Langerhans's 7 triples was tied for third most in the league with Choo Freeman (7), was and behind Damione Merriman (9), and Chone Figgins (14). Langerhans continued playing with the Class-A Advanced Myrtle Beach Pelicans in 2001. He batted .287 with 30 doubles, 3 triples, 7 home runs, 48 RBIs, and 22 stolen bases.