Life their DNA inside the cell nucleus and some of their DNA in organelles, such as mitochondria or chloroplasts. In contrast, prokaryotes (bacteria and archaea) store their DNA only in the cytoplasm. Within the chromosomes, chromatin proteins such as histones compact and organize DNA. These compact structures guide the interactions between DNA and other proteins, helping control which parts of the DNA are transcribed. DNA was first isolated by Friedrich Miescher in 1869. Its molecular structure was identified by James Watson and Francis Crick in 1953, whose model-building efforts were guided by X-ray diffraction data acquired by Rosalind Franklin. Life is
Timeline of United States discoveries chloride 1936 Elliptical galaxies 1936 Muons 1936 Vitamin E 1936 Sodium thiopental 1937 Niacin 1937 Electron capture 1938 Fluropolymers 1938 Animal echolocation 1938 Carme 1938 Lysithea 1940 Plutonium 1942 Cyanoacrylate 1943 Streptomycin 1944 Americium 1944 Curium 1946 Cloud seeding 1948 Warfarin 1948 Miranda 1948 Serotonin 1948 Tetracycline 1949 Nereid 1949 Berkelium 1950 Californium 1951 Barium stars 1951 Ananke 1952 Polio vaccine 1952 Einsteinium 1952 Rapid eye movement 1953 DNA structure In 1953, based on X-ray diffraction images and the information that the bases were paired, James D. Watson along with Francis Crick co-discovered what is now widely accepted as the