Light skin of UVA can penetrate deeply into the dermis in persons with light skin pigmentation with little protective melanin pigment. The characteristic of fair skin, red hair, and freckling is associated with high amount of pheomelanin, little amounts of eumelanin. This phenotype is caused by a loss-of-function mutation in the melanocortin 1 receptor (MC1R) gene. However, variations in the MC1R gene sequence only have considerable influence on pigmentation in populations where red hair and extremely fair skin is prevalent. The gene variation’s primary effect is to promote eumelanin synthesis at the expense of pheomelanin synthesis, although this contributes to very little
Pigment chemicals also have their own reflection and absorption patterns, which can affect the final spectrum. For example, in pigment/binder mixtures, individual rays of light may not encounter pigment molecules and may be reflected unchanged. These stray rays of source light make the mixture appear to have a less saturated color. Pure pigment allows very little white light to escape, producing a highly saturated color, while a small quantity of pigment mixed with a lot of white binder will appear unsaturated and pale due to incident white light escaping unchanged. Naturally occurring pigments such as ochres and iron oxides have been