Glipizide 10 milligrams. Glipizide sensitizes the beta cells of pancreatic islets of Langerhans insulin response, meaning that more insulin is released in response to glucose than would be without glipizide ingestion. Glipizide acts by partially blocking potassium channels among beta cells of pancreatic islets of Langerhans. By blocking potassium channels, the cell depolarizes, which results in the opening of voltage-gated calcium channels. The resulting calcium influx encourages insulin release from beta cells. Glipizide Glipizide is an oral rapid- and short-acting anti-diabetic medication from the sulfonylurea class. It is classified as a second-generation sulfonylurea, which means that it undergoes enterohepatic circulation. Second-generation
Ryan Langerhans In 2002, Langerhans was promoted to the Double-A Greenville Braves of the Southern League. He batted .251 with 23 doubles, 2 triples, 9 home runs, and 62 RBIs in 109 games. Langerhans was called up to the Atlanta Braves from the Double-A Greenville Braves in April, 2002. He appeared in one game that season where he had one at-bat against the Houston Astros where he did not record a hit. He was sent back down to the minors to start the 2003 season where he batted a combined .261 with 33 doubles, 4 triples, 10 home runs, and 49 RBIs