Prodrug not its intended target. This reduces adverse or unintended effects of a drug, especially important in treatments like chemotherapy, which can have severe unintended and undesirable side effects. Many herbal extracts historically used in medicine contain glycosides (sugar derivatives) of the active agent, which are hydrolyzed in the intestines to release the active and more bioavailable aglycone. For example, salicin is a β-D-glucopyranoside that is cleaved by esterases to release salicylic acid. Aspirin, acetylsalicylic acid, first made by Felix Hoffmann at Bayer in 1897, is a synthetic prodrug of salicylic acid. However, in other cases, such as codeine and morphine,
Love Is the Drug Love Is the Drug "Love Is the Drug" is a 1975 single from English rock band Roxy Music's fifth studio album "Siren". The song was the lead single taken from the album "Siren". A number two hit in the United Kingdom, it also gave the group its first substantial exposure in the United States, reaching number 30 in early 1976 on the US "Billboard" Hot 100 and doing even better on progressive rock radio. Its B-side in most countries was "Sultanesque", a non-LP instrumental track written by Ferry, which is now available on "The Thrill of It All" boxset. The