Nav1.5 kb. The gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5’ untranslated region (5’UTR) and exon 28 the 3’ untranslated region (3’UTR) of the RNA. SCN5A is part of a family of 10 genes that encode different types of sodium channels, i.e. brain-type (Na1.1, Na1.2, Na1.3, Na1.6), neuronal channels (Na1.7, Na1.8 and Na1.9), skeletal muscle channels (Na1.4) and the cardiac sodium channel Na1.5. SCN5A is mainly expressed in the heart, where expression is abundant in working myocardium and conduction tissue. In contrast, expression is low in the sinoatrial node and atrioventricular node.
Orbital node terms αναβιβάζων and καταβιβάζων were also used for the ascending and descending nodes, giving rise to the English words "anabibazon" and "catabibazon". For the orbit of the Moon around Earth, the plane is taken to be the ecliptic, not the equatorial plane. The gravitational pull of the Sun upon the Moon causes its nodes to gradually precess westward, completing a cycle in approximately 18.6 years. Orbital node An orbital node is either of the two points where an orbit intersects a plane of reference to which it is inclined. A non-inclined orbit, which is contained in the reference plane, has