Willow active extract of the bark, called salicin, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the compound in its pure state. In 1897, Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the "Spiraea" plant), which caused less digestive upset than pure salicylic acid. The new drug, formally acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Some of humans'
Worse is better Rise of Worse is Better", Gabriel claimed that "Worse-is-Better" is a model of software design and implementation which has the following characteristics (in approximately descending order of importance): Gabriel argued that early Unix and C, developed by Bell Labs, are examples of this design approach. Gabriel contrasted his philosophy with what he called the "MIT/Stanford style of design" or "MIT approach" (also known as "the Right Thing"), which he described as follows. Contrasts are in bold: Gabriel argued that "Worse is better" produced more "successful" software than the MIT approach: As long as the initial program is basically good, it