Tendon the presence of denatured collagen are factors that are believed to cause weakening of the tendon ECM and an increase in the potential for another rupture to occur. In response to repeated mechanical loading or injury, cytokines may be released by tenocytes and can induce the release of MMPs, causing degradation of the ECM and leading to recurring injury and chronic tendinopathies. A variety of other molecules are involved in tendon repair and regeneration. There are five growth factors that have been shown to be significantly upregulated and active during tendon healing: insulin-like growth factor 1 (IGF-I), platelet-derived growth factor
Inelastic collision at the nucleus. However, in the case of the proton, the evidence suggested three distinct concentrations of charge (quarks) and not one. The formula for the velocities after a one-dimensional collision is: where In a center of momentum frame the formulas reduce to: For two- and three-dimensional collisions the velocities in these formulas are the components perpendicular to the tangent line/plane at the point of contact. The normal impulse is: Giving the velocity updates: A perfectly inelastic collision occurs when the maximum amount of kinetic energy of a system is lost. In a perfectly inelastic collision, i.e., a zero coefficient