Sinoatrial node also activates a potassium channel, which allows K to flow out of the cell, making the membrane potential more negative and slowing the pacemaker potential, therefore decreasing the rate of action potential production and therefore decreasing heart rate. A decrease in heart rate is known as negative chronotropy. The first cell to produce the action potential in the SA node isn’t always the same, this is known as pacemaker shift. In certain species of animals, for example, in dogs, a superior shift (i.e. the cell that produces the fastest action potential in the SA node is higher than previously) usually
Sentinel node list, can be simplified remarkably using a sentinel node to demarcate the beginning and end of the list. Following is a Python implementation of a circular doubly-linked list: Notice how the codice_13 method takes the node that will be displaced by the new node in the parameter codice_14. For appending to the left, this is the head of a non-empty list, while for appending to right, it is the tail. But because of how the linkage is setup to refer back to the sentinel, the code just works for empty lists as well, where codice_14 will be the sentinel node.