Biconcave disc characteristic red color and transport oxygen from the lungs to the tissues. Mature red blood cells are round and biconcave because they lack a nucleus and unlike other cells, red cells require a small amount of oxygen for its metabolism and most oxygen is freed into the tissues. The absence of nucleus, ribosomes, and mitochondria partly contributes to the red blood cell’s disc-like structure which leaves room for hundreds of millions of hemoglobin molecules found within the cells. Hemoglobin is a red and iron-rich protein that merges with oxygen to carry oxygen from the lungs to the body tissues. Both
Blood volume Blood volume Blood volume is the volume of blood (both red blood cells and plasma) in the circulatory system of any individual. A typical adult has a blood volume of approximately 5 liters, with females and males having approximately the same blood volume. Blood volume is regulated by the kidneys. Blood volume (BV) can be calculated given the hematocrit (HC; the fraction of blood that is red blood cells) and plasma volume (PV), with the hematocrit being regulated via the blood oxygen content regulator: Blood volume measurement may be used in people with congestive heart failure, chronic hypertension, renal failure