Origin of the domestic dog matched across Eurasia and its branch is phylogenetically rooted in the same sequence as the Altai dog (not a direct ancestor). The subclade d2 hybrid haplotypes are found in 2.6% of South-West Asian dogs. Haplogroup E: Derived from post-domestication wolf–dog hybridization in East Asia, (rare distribution in South-East Asia, Korea and Japan). Haplogroup F: Derived from post-domestication wolf–dog hybridization in Japan. A study of 600 dog specimens found only one dog whose sequence indicated hybridization with the extinct Japanese wolf. It is not known whether this hybridization was the result of humans selecting for phenotypic traits from local wolf populations
Origin of the domestic dog initial domestication and then later in breed formation. In 2018, a study identified 429 genes that differed between modern dogs and modern wolves. As the differences in these genes could also be found in ancient dog fossils, these were regarded as being the result of the initial domestication and not from recent breed formation. These genes are linked to neural crest and central nervous system development. These genes affect embryogenesis and can confer tameness, smaller jaws, floppy ears, and diminished craniofacial development, which distinguish domesticated dogs from wolves and are considered to reflect domestication syndrome. The study proposes that domestication