Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian Trifa Valerian Trifa Valerian Trifa (; monastic name of Viorel D. Trifa , known in Eastern Orthodox Church records as Valerian (Trifa); June 28, 1914 – January 28, 1987) was a Romanian Orthodox cleric and former fascist political activist, who served as archbishop of the Romanian Orthodox Church in America and Canada. For part of his life, he was a naturalized citizen of the United States. A prominent affiliate of the Iron Guard, a Romanian fascist organization also known as "the Legionnaire Movement", Trifa played a part in provoking the Legionnaires' Rebellion of 1941. His antisemitic discourse was suspected of helping