Capillary embryonic development new capillaries are formed through vasculogenesis, the process of blood vessel formation that occurs through a "de novo" production of endothelial cells which then form vascular tubes. The term angiogenesis denotes the formation of new capillaries from pre-existing blood vessels and already present endothelium which divides. Blood flows from the heart through arteries, which branch and narrow into arterioles, and then branch further into capillaries where nutrients and wastes are exchanged. The capillaries then join and widen to become venules, which in turn widen and converge to become veins, which then return blood back to the heart through
Helicine arteries of penis in increased levels of cyclic guanosine monophosphate (cGMP). cGMP in turn triggers relaxation of the smooth muscle and results in dilation of blood vessels. This signal is terminated when cGMP is broken down by the enzyme cGMP specific phosphodiesterase type 5 (PDE5), the enzyme that is targeted by sildenafil and other drugs that treat erectile dysfunction. By preventing PDE5 from breaking down cGMP, the effects of NO are amplified and vasodilation occurs, thus resulting in increased penile erection. Helicine arteries of penis The helicine arteries of penis are arteries in the penis. They are found in the corpora cavernosa penis.