Blood air to all of the cells of the body, and venous blood carries carbon dioxide, a waste product of metabolism by cells, to the lungs to be exhaled. However, one exception includes pulmonary arteries, which contain the most deoxygenated blood in the body, while the pulmonary veins contain oxygenated blood. Additional return flow may be generated by the movement of skeletal muscles, which can compress veins and push blood through the valves in veins toward the right atrium. The blood circulation was famously described by William Harvey in 1628. In vertebrates, the various cells of blood are made in the
Vein and veins; these were later discovered by Marcello Malpighi in 1661. In 1956, André Frédéric Cournand, Werner Forssmann and Dickinson W. Richards were awarded the Nobel Prize in Medicine "for their discoveries concerning heart catheterization and pathological changes in the circulatory system." In his Nobel lecture, Forssmann credits Harvey as birthing cardiology with the publication of his book in 1628. In the 1970s, Diana McSherry developed computer-based systems to create images of the circulatory system and heart without the need for surgery. Vein Veins are blood vessels that carry blood toward the heart. Most veins carry deoxygenated blood from the