Causes of transsexuality Docter and others, but opposed by Charles Allen Moser, Larry Nuttbrock, Julia Serano, and the World Professional Association for Transgender Health.<section end="factors" /> A 2008 study compared 112 male-to-female transsexuals (both androphilic and gynephilic), mostly already undergoing hormone treatment, with 258 cisgender male controls. Male-to-female transsexuals were more likely than cisgender males to have a longer version of a receptor gene (longer repetitions of the gene) for the sex hormone androgen or testosterone, which reduced its effectiveness at binding testosterone. The androgen receptor (NR3C4) is activated by the binding of testosterone or dihydrotestosterone, where it plays a critical role in
Sexual desire and intimate relationships primary goal of sexual desire. It has also been suggested that women are more likely than men to develop a “relational” or “person-centered” orientation to sexual desire, whereas men are more likely to adopt a “recreational” or “body-centered” orientation to sexuality. These results further support the suggestion that despite generally consistent definitions of sexual desire, perceived differing end goals of sexual desire may exist between the sexes. In keeping with providing definitions of sexual desire consistent with those of theorists, both men and women have consistently expressed their beliefs that the causes of male sexual desire differ from female causes