Scar healing which heals with a scar. The myofibroblasts make up a high proportion of the fibroblasts proliferating in the postembryonic wound at the onset of healing. In the rat model, for instance, myofibroblasts can constitute up to 70% of the fibroblasts, and is responsible for fibrosis on tissue. Generally, the myofibroblasts disappear from the wound within 30 days, but can stay around in pathological cases in hypertrophy, such as keloids. Myofibroblasts have plasticity and in mice can be transformed into fat cells, instead of scar tissue, via the regeneration of hair follicles. Early and effective treatment of acne scarring can
The Madness of King Scar primarily positive reviews from music critics. Ben Hewis of WhatsOnStage.com included the song in his list of his top five favorite show tunes, writing that it "shin[ed] a humanising light on the thought process of Scar is brilliantly effective storytelling". Hewis found the track to be an interesting exploration of Scar, and felt its removal from current productions of the musical was disappointing. Featuring it as an example of why Scar was one of the "15 most terrifying musical theater villains", "Backstage"'s KC Wright described it as a "snarling signature song". Megan Green of Australian Stage wrote that "The Madness