Bone cancer in cats and dogs Bone cancer in cats and dogs The most common bone tumor is called osteosarcoma, and typically affects middle-age to older dogs of large and giant breeds. Osteosarcoma is less common in cats. Osteosarcoma is an aggressive cancer that can develop in any bone of the body but the majority is seen in the limbs (e.g. long bones such as radius, humerus, femur, and tibia). Dogs with limb osteosarcoma typically show lameness and swelling at the affected site. For other sites, dogs may show difficulty to open their mouth (if jaw bone cancer), nasal discharge (if nasal cavity bone cancer) or
The Biggest Douche in the Universe are friends of Trey Parker and Matt Stone and have stated that this is their favorite episode. According to the commentary for this episode, Trey Parker described the creation of the episode as being centered on John Edward who the entire crew of South Park Studios agreed was "the biggest douche in the universe." That was until Matt Stone asked the question "Well, what about Rob Schneider?" leading to the fictional trailers. Parker and Stone credit James Randi with Stan's explanation of cold reading. The Biggest Douche in the Universe "The Biggest Douche in the Universe" is the 15th episode