Heart valve chambers are lined with endocardium. Heart valves separate the atria from the ventricles, or the ventricles from a blood vessel. Heart valves are situated around the fibrous rings of the cardiac skeleton. The valves incorporate leaflets or cusps, which are pushed open to allow blood flow and which then close together to seal and prevent backflow. The mitral valve has two cusps, whereas the others have three. There are nodules at the tips of the cusps that make the seal tighter. The pulmonary valve has left, right, and anterior cusps. The aortic valve has left, right, and posterior cusps. The
How Many Licks? Neptunes has additional vocals from American artists Kelis, Lil' Cease, and Snoop Dogg. "How Many Licks?" was praised by music critics after its release and in retrospective reviews; the Neptunes remix also received positive reviews. However, African-American studies professor Mark Anthony Neal criticized the song's treatment of black female sexuality. Commentators compared its content to Trinidadian-American rapper Nicki Minaj's 2014 single, "Anaconda". "How Many Licks?" peaked at number 75 on the "Billboard" Hot 100 chart and charted in several other countries, but was not as commercially successful as Lil' Kim's previous releases. The song's music video was directed by Francis