Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian (herb) of well-matured cheese. Though some people remain partial to the earthy scent, some find it unpleasant, comparing the odor to that of unwashed feet. Although valerian is a common traditional medicine used for treating insomnia, there is no good evidence it is effective for this purpose, and there is some concern it may be harmful. Valerian is not helpful in treating restless leg syndrome or anxiety. There is insufficient evidence for efficacy and safety of valerian for anxiety disorders. The European Medicines Agency (EMA) approved the health claim that valerian can be used as a traditional herbal medicine to relieve