Pharmacodynamics of progesterone women, this effect being the result of suppression of the mid-cycle surge in gonadotropin secretion, is 300 mg/day. However, this figure is based on limited clinical data. Conversely, treatment with a high dosage of oral progesterone of 100 mg four times per day (or 400 mg/day total) in men for 10 days that resulted in approximately mid-luteal phase levels of progesterone (7.9–9.4 ng/mL; measured by ) did not cause any change in testosterone levels, suggesting that progesterone has little or no antigonadotropic effect in males at typical clinical dosages. In addition, a study found that administration of 1,000 mg/day oral
Menstrual cycle extra-pair flirtations and demonstrate a preference for extra pair copulation. Preferences for voice pitch change across the cycle. When seeking a short term mating partner, women may prefer a male with a low voice pitch, particularly during the fertile phase. During the late follicular phase, it is common for women demonstrate a preference for mates with a masculine, deep voice. Research has also been conducted on the attractiveness of the female voice throughout the cycle. During their most fertile phase of the menstrual cycle, there is some evidence that female voices are rated as significantly more attractive. This effect is