Anatomy of the cerebellum major part of the cerebellum by mass, but in other vertebrates, it is typically the spinocerebellum. In amphibians, lampreys, and hagfish the cerebellum is little developed; in the latter two groups it is barely distinguishable from the brain-stem. Although the spinocerebellum is present in these groups, the primary structures are small paired nuclei corresponding to the vestibulocerebellum. The cerebellum follows the general groups-of-three pattern found in anatomy, with three major input and output cerebellar peduncles (fiber bundles). These are the superior (brachium conjunctivum), middle (brachium pontis), and inferior (restiform and juxtarestiform bodies) cerebellar peduncles. There are three sources of input
Anatomy of the cerebellum the numerous and tiny granule cells, the slightly larger unipolar brush cells and the much larger Golgi cells. Mossy fibers enter the granular layer from their main point of origin, the pontine nuclei. These fibers form excitatory synapses with the granule cells and the cells of the deep cerebellar nuclei. The granule cells send their T-shaped axons—known as parallel fibers—up into the superficial molecular layer, where they form hundreds of thousands of synapses with Purkinje cell dendrites. The human cerebellum contains on the order of 60 to 80 billion granule cells, making this single cell type by far the most