Corpus luteum is essential for establishing and maintaining pregnancy in females. The corpus luteum secretes progesterone, which is a steroid hormone responsible for the decidualization of the endometrium (its development) and maintenance, respectively. It also produces relaxin, a hormone responsible for softening of the pubic symphysis which helps in parturition. If the egg is not fertilized, the corpus luteum stops secreting progesterone and decays (after approximately 10 days in humans). It then degenerates into a corpus albicans, which is a mass of fibrous scar tissue. The uterine lining (endometrium) is expelled through the vagina (in mammals that go through a menstrual cycle).
Menstrual cycle coinciding with the time of menstruation, or coinciding with the time of ovulation), and the frequency with which they occur has not been firmly established. Using one particular definition, one group of scientists found that around one-third of women with intractable partial epilepsy has catamenial epilepsy. An effect of hormones has been proposed, in which progesterone declines and estrogen increases would trigger seizures. Recently, studies have shown that high doses of estrogen can cause or worsen seizures, whereas high doses of progesterone can act like an antiepileptic drug. Studies by medical journals have found that women experiencing menses are 1.68