Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian Gunia Valerian Gunia Valerian "Valiko" Gunia (; 21 January 1862 – 31 July 1938) was a Georgian dramatist, actor, director, critic, and translator. His contribution to the Georgian scene won him the title of People's Artist in 1934. Born in the village of Eki, Kutais Governorate, Russian Empire, in what is now the Senaki Municipality of a family of untitled Mingrelian nobility, Gunia attended the "realschule" in Tiflis until being expelled for participation in student protests in 1881. He then studied at the Petrovsko-Razumovsky Agricultural Academy in Moscow. In 1882 he joined the Georgian Dramatical Troupe in Tiflis. As an actor,