Cultured pearl is calcium carbonate and a fibrous protein called conchiolin. As the nacre builds up in layers of minute aragonite tablets, it fills the growing pearl sac and eventually forms a pearl. Natural pearls are formed by nature, more or less by chance. On the other hand, cultured pearls are human creations formed by inserting a tissue graft from a donor oyster, upon which a pearl sac forms, and the inner side precipitates calcium carbonate, in the form of nacre or "mother-of-pearl". The most popular and effective method for creating cultured pearls are made from the shells of freshwater river mussels
Pearl Slaghoople to date is in the 1993 animated film "", in which she is voiced by Janet Waldo. Pearl Slaghoople appears in both live-action adaptations of the series: Pearl Slaghoople Pearl Slaghoople is a fictional character on the animated TV show "The Flintstones". She is the mother of Wilma Flintstone, who is married to Fred Flintstone. In the original series, she portrays Fred's stereotypically antagonistic mother-in-law, acting as a nagging irritant. Her appearance was similar to Wilma's, although Pearl was noticeably larger-figured, similar in build to the men of Bedrock rather than the more shapely Wilma and Betty. In the original