Sinoatrial node therefore cause ischaemia and cell death in the SA node. This can disrupt the electrical pacemaker function of the SA node, and can result in sick sinus syndrome. If the SA node does not function, or the impulse generated in the SA node is blocked before it travels down the electrical conduction system, a group of cells further down the heart will become its pacemaker. The sinoatrial node was first discovered by a young medical student, Martin Flack, in the heart of a mole, whilst his mentor, Sir Arthur Keith, was on a bicycle ride with his wife. They made
Node influence metric probabilities. The accessibility has been shown to reveal community structure in urban networks, corresponds to the number of nodes which can be visited in a defined time period, and is predictive of the outcome of epidemiological SIR model spreading processes on networks with large diameter and low density. The expected force measures node influence from an epidemiological perspective. It is the expected value of the force of infection generated by the node after two transmissions. The expected force of a node formula_4 is given by where the sum is taken over the set formula_9 of all possible transmission clusters resulting