Holoaden Holoaden Holoaden (common name: highland frogs) is a small genus of craugastorid frogs endemic to southeastern Brazil. "Holoaden" is the type genus of subfamily Holoadeninae that was erected in 2008 and placed in family Strabomantidae, erected at the same time. Before that, it was in Brachycephalidae. However, later research has led the whole Strabomantidae, Holoadeninae included, to become included in Craugastoridae. This arrangement is not followed by all, and the AmphibiaWeb still keeps Holoadeninae, and consequently "Holoaden", in Strabomantidae. "Holoaden" grow to snout–vent length at most. Head is narrower than the body. Differentiated tympanic membrane and tympanic annulus are absent.
Membrane operating conditions, cost and performance, it should prevented, and if necessary, removed. Optimizing the operation conditions is important to prevent fouling. However, if fouling has already taken place, it should be removed by using physical or chemical cleaning. Physical cleaning techniques for membrane include membrane relaxation and membrane backwashing. Chemical cleaning. Relaxation and backwashing effectiveness will decrease with operation time as more irreversible fouling accumulates on the membrane surface. Therefore, besides the physical cleaning, chemical cleaning may also be recommended. They include: Optimizing the operation condition. Several mechanisms can be carried out to optimize the operation conditions of the membrane