Tympanic part of the temporal bone upper part of the posterior wall by the squama. Its inner end is closed, by the tympanic membrane which originates from the tympanic sulcus; the upper limit of its outer orifice is formed by the posterior root of the zygomatic process, immediately below which there is sometimes seen a small spine, the "suprameatal spine", situated at the upper and posterior part of the orifice. The auditory bulla (pl. bullae) is a hollow bony structure on the ventral, posterior portion of the skull that encloses parts of the middle and inner ear. In most species, it is formed by the tympanic
Integral membrane protein at atomic resolution by X-ray crystallography or nuclear magnetic resonance spectroscopy. They are challenging subjects for study owing to the difficulties associated with extraction and crystallization. In addition, structures of many water-soluble protein domains of IMPs are available in the Protein Data Bank. Their membrane-anchoring α-helices have been removed to facilitate the extraction and crystallization. Search integral membrane proteins in the PDB (based on gene ontology classification) IMPs can be divided into two groups: The most common type of IMP is the transmembrane protein (TM), which spans the entire biological membrane. Single-pass membrane proteins cross the membrane only once, while