Apparent mineralocorticoid excess syndrome cases recorded worldwide. Liquorice consumption may also cause a temporary form of AME due to its ability to block 11β-hydroxysteroid dehydrogenase type 2, in turn causing increased levels of cortisol. Cessation of licorice consumption will reverse this form of AME. Apparent mineralocorticoid excess syndrome Apparent mineralocorticoid excess (AME) is an autosomal recessive disorder causing hypertension (high blood pressure) and hypokalemia (abnormally low levels of potassium). It was found by Dr Maria I. New at Weil Cornell Hospital in New York City. It results from mutations in the "HSD11B2" gene, which encodes the kidney isozyme of 11β-hydroxysteroid dehydrogenase type 2. In
Water organ a working replica of hydraulis was made based on the archaeological finding and on ancient descriptions. The remains of the ancient hydraulis are exhibited at the Archaeological Museum of Dion. Water organ The water organ or hydraulic organ () (early types are sometimes called hydraulos, hydraulus or hydraula) is a type of pipe organ blown by air, where the power source pushing the air is derived by water from a natural source (e.g. by a waterfall) or by a manual pump. Consequently, the water organ lacks a bellows, blower, or compressor. The hydraulic organ is often confused with the hydraulis.