Tendon induce endothelial cell proliferation and migration, and VEGF mRNA has been shown to be expressed at the site of tendon injuries along with collagen I mRNA. Bone morphogenetic proteins (BMPs) are a subgroup of TGF-β superfamily that can induce bone and cartilage formation as well as tissue differentiation, and BMP-12 specifically has been shown to influence formation and differentiation of tendon tissue and to promote fibrogenesis. In animal models, extensive studies have been conducted to investigate the effects of mechanical strain in the form of activity level on tendon injury and healing. While stretching can disrupt healing during the initial
Conjoint tendon Conjoint tendon The conjoint tendon (previously known as the inguinal aponeurotic falx) is a structure formed from the lower part of the common aponeurosis of the internal oblique muscle and the transversus abdominis as it inserts into the crest of the pubis and pectineal line immediately behind the superficial inguinal ring. It is usually conjoint with the tendon of the internal oblique muscle, but they may be separate as well. It forms the medial part of the posterior wall of the inguinal canal. The conjoint tendon serves to protect what would otherwise be a weak point in the abdominal wall.