Anatomy of the cerebellum to describe the cellular structure is to begin with the inputs and follow the sequence of connections through to the outputs. The four deep nuclei of the cerebellum are the dentate, emboliform, globose, and fastigii nuclei and they act as the main centers of communication, sending and receiving information to and from specific parts of the brain. In addition, these nuclei receive both inhibitory and excitatory signals from other parts of the brain which in turn affect the nuclei's outgoing signals.(The globose and the emboliform nuclei make up the interposed nucleus). The cytoarchitecture (cellular organization) of the cerebellum is highly
Anatomy of the cerebellum has been shown to undergo synaptic plasticity. This allows the circuitry of the cerebellar cortex to continuously adjust and fine-tune the output of the cerebellum, forming the basis of some types of motor learning and coordination. Each layer in the cerebellar cortex contains the various cell types that comprise this circuitry. This outermost layer of the cerebellar cortex contains two types of inhibitory interneurons: the stellate and basket cells. It also contains the dendritic arbors of Purkinje neurons and parallel fiber tracts from the granule cells. Both stellate and basket cells form GABAergic synapses onto Purkinje cell dendrites. The middle