Endocrine gland been implicated in proliferation, one of the required steps of oncogenesis. Other common diseases that result from endocrine dysfunction include Addison’s disease, Cushing’s disease and Grave’s disease. Cushing's disease and Addison's disease are pathologies involving the dysfunction of the adrenal gland. Dysfunction in the adrenal gland could be due to primary or secondary factors and can result in hypercortisolism or hypocortisolism . Cushing’s disease is characterized by the hypersecretion of the adrenocorticotropic hormone (ACTH) due to a pituitary adenoma that ultimately causes endogenous hypercortisolism by stimulating the adrenal glands. Some clinical signs of Cushing’s disease include obesity, moon face, and
Endocrine disruptor and toddlers ingest more contaminated house dust than the adults they live with, and therefore have much higher levels of pollutants in their systems. Consumer goods are another potential source of exposure to endocrine disruptors. An analysis of the composition of 42 household cleaning and personal care products versus 43 "chemical free" products has been performed. The products contained 55 different chemical compounds: 50 were found in the 42 conventional samples representing 170 product types, while 41 were detected in 43 "chemical free" samples representing 39 product types. Parabens, a class of chemicals that has been associated with reproductive-tract issues,