Cell cycle levels in S and at their lowest near mitosis. Cell cycle The cell cycle, or cell-division cycle, is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells. In bacteria, which lack a cell nucleus, the cell cycle is divided into the B, C, and D periods. The B period extends from the end of cell division to the beginning of DNA replication. DNA replication occurs during the C period. The D period refers to the stage between the end of DNA replication and
Calcium signaling in cell division cell lines, that the G2/M checkpoint is regulated by CaMKII and MAPK crosstalk. Here, CaMKII activates MEK/ERK, which degrades the cell cycle arresting p27 protein In general, transformed cells proliferate in a calcium-independent manner, whereas non-transformed cells show high sensitivity to extra-cellular calcium concentration, suggesting oncogenic growth may include disruption of calcium signaling. Condensation of chromatin is a vital step in cell division, allowing cells to equally distribute chromosomes to the daughter cells. Recent work has suggested that Ca is required for enabling chromatin condensation in prometaphase. Calcium was found to concentrate on condensed DNA to much higher levels compared