Nav1.5 kb. The gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5’ untranslated region (5’UTR) and exon 28 the 3’ untranslated region (3’UTR) of the RNA. SCN5A is part of a family of 10 genes that encode different types of sodium channels, i.e. brain-type (Na1.1, Na1.2, Na1.3, Na1.6), neuronal channels (Na1.7, Na1.8 and Na1.9), skeletal muscle channels (Na1.4) and the cardiac sodium channel Na1.5. SCN5A is mainly expressed in the heart, where expression is abundant in working myocardium and conduction tissue. In contrast, expression is low in the sinoatrial node and atrioventricular node.
Exposed node problem Exposed node problem In wireless networks, the exposed node problem occurs when a node is prevented from sending packets to other nodes because of a neighboring transmitter. Consider an example of 4 nodes labeled R1, S1, S2, and R2, where the two receivers (R1, R2) are out of range of each other, yet the two transmitters (S1, S2) in the middle are in range of each other. Here, if a transmission between S1 and R1 is taking place, node S2 is prevented from transmitting to R2 as it concludes after carrier sense that it will interfere with the transmission by