Glycogen debranching enzyme Glycogen debranching enzyme A debranching enzyme is a molecule that helps facilitate the breakdown of glycogen, which serves as a store of glucose in the body, through glucosyltransferase and glucosidase activity. Together with phosphorylases, debranching enzymes mobilize glucose reserves from glycogen deposits in the muscles and liver. This constitutes a major source of energy reserves in most organisms. Glycogen breakdown is highly regulated in the body, especially in the liver, by various hormones including insulin and glucagon, to maintain a homeostatic balance of blood-glucose levels. When glycogen breakdown is compromised by mutations in the glycogen debranching enzyme, metabolic diseases such
The body in traditional Chinese medicine of all the Yin and Yang energy in the body. The Kidneys also govern the endocrine system, receive air from the lungs, govern bones, govern teeth, control water in the body, and store essence. Dysfunction of the Kidneys leads to deficiencies of Yin or Yang. It also leads to imbalanced hormones, weak bones, an impaired sex drive, and dizziness. Water in excess leads to bipolar disorder. Depressive episodes are characterized by Kidney Yin excess while manic episodes are characterized by Kidney Yang excess. The Kidney Meridian begins on the sole, moves up the inner leg to the groin, up the