Red blood cell synthesised by the kidney. Just before and after leaving the bone marrow, the developing cells are known as reticulocytes; these constitute about 1% of circulating red blood cells. The functional lifetime of a red blood cell is about 100–120 days, during which time the red blood cells are continually moved by the blood flow push (in arteries), pull (in veins) and a combination of the two as they squeeze through microvessels such as capillaries. They are also recycled in the bone marrow. The aging red blood cell undergoes changes in its plasma membrane, making it susceptible to selective recognition by
Trabecular veins radicle of a vein. On the outer surfaces of these cells are seen delicate transverse lines or markings, which are due to minute elastic fibrillæ arranged in a circular manner around the sinus. Thus the channel obtains an external investment, and gradually becomes converted into a small vein, which after a short course acquires a coat of ordinary connective tissue, lined by a layer of flattened epithelial cells which are continuous with the supporting cells of the pulp. The smaller veins unite to form larger ones; these do not accompany the arteries, but soon enter the trabecular sheaths of the