Bone vessels and cartilage. In the human body at birth, there are over 270 bones, but many of these fuse together during development, leaving a total of 206 separate bones in the adult, not counting numerous small sesamoid bones. The largest bone in the body is the femur or thigh-bone, and the smallest is the stapes in the middle ear. The Greek word for bone is ὀστέον ("osteon"), hence the many terms that use it as a prefix – such as osteopathy. Bone is not uniformly solid, but consists of a flexible matrix (about 30%) and bound minerals (about 70%) which
Effect of spaceflight on the human body on the bones, there is a rapid increase in bone loss, from 3% cortical bone loss per decade to about 1% every month the body is exposed to microgravity, for an otherwise healthy adult. The rapid change in bone density is dramatic, making bones frail and resulting in symptoms which resemble those of osteoporosis. On Earth, the bones are constantly being shed and regenerated through a well-balanced system which involves signaling of osteoblasts and osteoclasts. These systems are coupled, so that whenever bone is broken down, newly formed layers take its place—neither should happen without the other, in a healthy