Human digestive system the esophagus at its upper end and to the duodenum at its lower end. Gastric acid (informally "gastric juice"), produced in the stomach plays a vital role in the digestive process, and mainly contains hydrochloric acid and sodium chloride. A peptide hormone, gastrin, produced by G cells in the gastric glands, stimulates the production of gastric juice which activates the digestive enzymes. Pepsinogen is a precursor enzyme (zymogen) produced by the gastric chief cells, and gastric acid activates this to the enzyme pepsin which begins the digestion of proteins. As these two chemicals would damage the stomach wall, mucus is
Calponin 3, acidic in mouse CC myoblasts inhibited cell fusion during "in vitro" differentiation, whereas "Cnn3" gene knockdown promoted cell fusion and the expression of skeletal muscle myosin. The inhibitory effect of calponin 3 was reversed upon phosphorylation by Rho-associated kinase 1/2 (ROCK1/2). Calponin 3, acidic Calponin 3. acidic is a protein that in humans is encoded by the "CNN3" gene. The "CNN3" gene is located at 1p22-p21 in the human chromosomal genome. "CNN3" gene contains 7 exons and encodes calponin 3, a 36.4-kDa protein consisting of 329 amino acids with isoelectric point (pI) of 5.84. Calponin 3 is known as acidic calponin.