Pharmacokinetics of progesterone concentrations was around 4 hours and the elimination half-life was in the range of 30 to 40 hours. The venous blood levels observed were very low. Because progesterone is a lipophilic and hydrophobic compound, it is not absorbed efficiently by the skin. Moreover, because the body produces about 25 mg progesterone per day on average during the luteal phase, around 50% of the body would need to be used as a surface of absorption to deliver a similar quantity of progesterone. As such, the transdermal route cannot easily achieve adequate circulating progesterone levels, and this makes transdermal progesterone impractical for
Menstrual synchrony of northwestern California, according to one ethnographic study, "all of a household's fertile women who were not pregnant menstruated at the same time..." The phenomenon of menstrual synchrony is the closeness in time of the menstrual cycle onsets of two or more women. The phenomenon is not synchronization in the strict sense of concordance of menstrual cycle onsets but the term "menstrual synchrony" is still used perhaps misleadingly. As an undergraduate, Martha McClintock published the first study on menstrual synchrony; her report detailed the menstrual synchrony of undergraduate women living in a dormitory in Wellesley College. Since then, there have