Myocyte coordinate contraction throughout the remaining heart muscle via the electrical conduction system of the heart. Sinoatrial node activity is modulated, in turn, by nerve fibres of both the sympathetic and parasympathetic nervous systems. These systems act to increase and decrease, respectively, the rate of production of electrical impulses by the sinoatrial node. There are numerous methods employed for fiber-typing, and confusion between the methods is common among non-experts. Two commonly confused methods are histochemical staining for myosin ATPase activity and immunohistochemical staining for Myosin heavy chain (MHC) type. Myosin ATPase activity is commonly—and correctly—referred to as simply "fiber type", and
Node 4 Node 4 Node 4, also known as the Docking Hub System (DHS), is a proposed module of the International Space Station (ISS). As of 2011 NASA was considering a 40-month design and development effort for Node 4 that would result in its launch in late 2013. Node 4 would be built using the Node Structural Test Article (STA) and docked to the forward port of the Harmony module. The Structural Test Article was built to facilitate testing of ISS hardware and was intended to become Node 1. However, during construction, structural design flaws were discovered. The under-construction Node 2 was