Thyroid often carcinomas, although cancer can occur in any tissue that the thyroid consists of, including cancer of C-cells and lymphomas. Cancers from other sites also rarely lodge in the thyroid. Radiation of the head and neck presents a risk factor for thyroid cancer, and cancer is more common in women than men, occurring at a rate of about 2:1. In most cases, thyroid cancer presents as a painless mass in the neck. It is very unusual for thyroid cancers to present with other symptoms, although in some cases cancer may cause hyperthyroidism. Most malignant thyroid cancers are papillary, followed by
Computed tomography of the thyroid without suspicious features should not undergo further evaluation. Nevertheless, further workup might be necessary for such individuals if it is clinically warranted, or specifically requested by the referring physician or the patient. In patients with ITNs, it is important to inquire about pertinent historical factors predicting malignancy. These factors include history of childhood or adolescent head and neck or total body radiation exposure, and familial thyroid carcinoma or thyroid cancer syndrome. Syndromes associated with thyroid cancer include multiple endocrine neoplasia 2, familial adenomatous polyposis, Carney complex, Cowden’s disease, and Werner syndrome/progeria. If a patient has a first-degree relative with such