Antibiotic resistance in gonorrhea Antibiotic resistance in gonorrhea The Gonorrhea bacterium Neisseria gonorrhoeae has developed antibiotic resistance to many antibiotics. The bacteria was first identified in 1879, although some Biblical scholars believe that references to the disease can be found as early as Parshat Metzora of the Old Testament. In the 1940s effective treatment with penicillin became available, but by the 1970s resistant strains predominated. Resistance to penicillin has developed through two mechanisms: chromasomally mediated resistance (CMRNG) and penicillinase-mediated resistance (PPNG). CMRNG involves step wise mutation of penA, which codes for the penicillin-binding protein (PBP-2); mtr, which encodes an efflux pump that removes penicillin
This Was Supposed to Be the Future This Was Supposed to Be the Future This Was Supposed to Be the Future is the third studio album by The Nextmen. It was released in June 2007 on Antidote Records. It was a change in their sound; a prevalence of songs over rap tracks. Ten different vocalists appear on the album. Zarif appears the most, with three tracks, and LSK and Dynamite MC both appear twice. The first single was "Let It Roll", featuring Alice Russell. The second single was "Something Got You", featuring singer-songwriter Zarif. At their album launch, The Nextmen performed as a full 10 piece band,