Computed tomography of the thyroid bone, before it loops posteriorly and inferiorly to the hyoid bone. Then it continues its descent into the infra-hyoid portion of the neck, anterior to the trachea, thyroid cartilage, and thyroid membrane. Any thyroid residual along the descent course may lead to the development of ectopic thyroid glands. Thyroid carcinomas, thyroiditis, and goiter may develop within any ectopic thyroid tissue. Thyroid scanning with technetium-99 m (Tc99m) plays an important role in detecting orthotopic and ectopic thyroid tissue. Both CT scans and US can help detect ectopic tissue when a lesion demonstrates imaging and enhancement characteristics of thyroid tissue. The absence
Thyroid genes being highly thyroid specific. The corresponding specific proteins are mainly involved in thyroid hormone synthesis, such as thyroglobulin, TPO and IYD, and expressed in follicular cells. Other proteins elevated in the thyroid are calcitonin related proteins such as CALCA and CALCB, expressed in the parafollicular c-cells. Excessive production of the thyroid hormones is called hyperthyroidism, which is most commonly a result of Graves' disease, a toxic multinodular goitre, a solitary thyroid adenoma, or inflammation. Other causes include drug-induced excess of iodine, particularly from amiodarone, an antiarrhythmic medication; an excess caused by the preferential uptake of iodine by the thyroid