Insulin characterized by abnormally high blood glucose concentrations, and generalized body wasting. In type 2 diabetes mellitus the destruction of beta cells is less pronounced than in type 1 diabetes, and is not due to an autoimmune process. Instead there is an accumulation of amyloid in the pancreatic islets, which likely disrupts their anatomy and physiology. The pathogenesis of type 2 diabetes is not well understood but patients exhibit a reduced population of islet beta-cells, reduced secretory function of islet beta-cells that survive, and peripheral tissue insulin resistance. Type 2 diabetes is characterized by high rates of glucagon secretion into the
Insulin pen pen systems: durable and prefilled: Most brands of insulin are now available for use in pens, these include: Insulin pens are used by 95% of insulin-treated patients in Europe, Asia, Australia and Scandinavia with excellent results. They are currently underutilized but growing in use in the United States. Insulin pens offer several significant advantages over insulin syringes: ease of handling, accuracy, and they are more discreet to use and easier to transport. Insulin pens have a number of advantages: It is important that proper injection sites on the body be used. A healthcare provider helps determine the best injection site