Red blood cell red blood cell cell membrane comprises a typical lipid bilayer, similar to what can be found in virtually all human cells. Simply put, this lipid bilayer is composed of cholesterol and phospholipids in equal proportions by weight. The lipid composition is important as it defines many physical properties such as membrane permeability and fluidity. Additionally, the activity of many membrane proteins is regulated by interactions with lipids in the bilayer. Unlike cholesterol, which is evenly distributed between the inner and outer leaflets, the 5 major phospholipids are asymmetrically disposed, as shown below: Outer monolayer Inner monolayer This asymmetric phospholipid distribution
Neonatal red cell transfusion baby (e.g. wristband). Paedipacks are multiple aliquots made from one adult blood donation. By using paedipacks, the baby is exposed to blood from fewer blood donors. ABO blood grouping and screening for antibodies in neonates differs from blood grouping in adults and older children. Any antibodies detected are the mother's antibodies rather than the baby's. Therefore, any donor blood given to the baby must be ABO and D compatible with both mother and baby; and antigen-negative for any clinically significant maternal antibodies. Necrotising enterocolitis may occur after a red cell transfusion in neonates, although there is an association between the