Kidney stone disease to a combination of genetics and environmental factors. Risk factors include high urine calcium levels, obesity, certain foods, some medications, calcium supplements, hyperparathyroidism, gout and not drinking enough fluids. Stones form in the kidney when minerals in urine are at high concentration. The diagnosis is usually based on symptoms, urine testing, and medical imaging. Blood tests may also be useful. Stones are typically classified by their location: nephrolithiasis (in the kidney), ureterolithiasis (in the ureter), cystolithiasis (in the bladder), or by what they are made of (calcium oxalate, uric acid, struvite, cystine). In those who have had stones, prevention is
Underactive bladder et al. (2014). "Pathophysiology and animal modeling of underactive bladder." Int Urol Nephrol 46 Suppl 1: 11-21. van Koeveringe, G. A., K. L. Rademakers, et al. (2014). "Detrusor underactivity: Pathophysiological considerations, models and proposals for future research. ICI-RS 2013." Neurourol Urodyn 33(5): 591-596. Underactive bladder Underactive bladder syndrome (UAB) describes symptoms of difficulty with bladder emptying, such as hesitancy to start the stream, a poor or intermittent stream, or sensations of incomplete bladder emptying. The physical finding of detrusor pressurization of insufficient strength or duration to ensure timely and efficient bladder emptying is properly termed "detrusor underactivity" (DU) (Abrams et