Origin of the domestic dog to the domestic dog and modern wolf lineages. The gray wolf is thought to be ancestral to the domestic dog, however its relationship to "C. variabilis", and the genetic contribution of "C. variabilis" to the dog, is the subject of debate. The Zhokhov Island (8,700 YBP) and Aachim (1,700 YBP) canid haplotypes fell within the domestic dog clade, cluster with S805, and also share their haplotypes with – or are one mutation away from – the Tibetan wolf ("C. l. chanco") and the recently-extinct Japanese wolf ("C. l. hodophilax"). This may indicate that these canids retained the genetic signature of
Ticks of domestic animals create a potentially fatal inflammatory crisis of the blood. The name redwater (coloured urine) derives from the hemoglobinuria caused by the destruction of red blood cells infected with the merozoite stage of "Babesia"; anemia results from the same destruction. Horses suffer babesiosis or biliary fever when infected by "Ba. equi" or "B. caballi". This occurs in many countries where vector ticks are found, such as "R. e. evertsi", "Hy. truncatum", and "D. nitens". Dogs are at risk from severe infection with "Ba. canis" and its subspecies, transmitted by the dog ticks "R. sanguineus", "D. reticulatus", and "Ha. leachi". Domestic cats