Apparent mineralocorticoid excess syndrome cases recorded worldwide. Liquorice consumption may also cause a temporary form of AME due to its ability to block 11β-hydroxysteroid dehydrogenase type 2, in turn causing increased levels of cortisol. Cessation of licorice consumption will reverse this form of AME. Apparent mineralocorticoid excess syndrome Apparent mineralocorticoid excess (AME) is an autosomal recessive disorder causing hypertension (high blood pressure) and hypokalemia (abnormally low levels of potassium). It was found by Dr Maria I. New at Weil Cornell Hospital in New York City. It results from mutations in the "HSD11B2" gene, which encodes the kidney isozyme of 11β-hydroxysteroid dehydrogenase type 2. In
Bidder's organ oocytes (egg cells). Only rudimentary oviducts are developed, though, preventing eggs from actually being laid. The Bidder's organ only develops into an ovary analogue when testes are removed experimentally or not functioning properly (e.g. due to exposure to endocrine-disrupting chemicals). Importantly, females can have Bidder's organs in addition to true ovaries, which suggests that the Bidder's organ might not be a rudimentary ovary. It is named in honour of Friedrich Bidder. The organ's internal anatomy consists of two parts; the central portion, consisting of connective tissue and rich in blood vessels, and its periphery, consisting of the cortex, which contains