Hair conditioner the hair a positive charge and creates more hydrogen bonds among the keratin scales, giving the hair a more compact structure. Organic acids such as citric acid are usually used to maintain acidity. Hair conditioner Hair conditioner is a hair care product used to improve the feel, appearance and manageability of hair. Its main purpose is to reduce friction between strands of hair to allow easier brushing or combing, which might otherwise cause damage. Various other benefits are often advertised, such as hair repair, strengthening, or a reduction in split-ends. Conditioners are available in a wide range of forms including
Retinoblastoma protein of DREAM requires DYRK1A (Ser/Thr kinase) dependant phosphorylation of the MuvB core component, Lin52 at Serine28. This mechanism is crucial for recruitment of p130/p107 to the MuvB core and thus DREAM assembly. The retinoblastoma protein is involved in the growth and development of mammalian hair cells of the cochlea, and appears to be related to the cells' inability to regenerate. Embryonic hair cells require Rb, among other important proteins, to exit the cell-cycle and stop dividing, which allows maturation of the auditory system. Once wild-type mammals have reached adulthood, their cochlear hair cells become incapable of proliferation. In studies where