History of diabetes further clarified in 1921, when Sir Frederick Grant Banting and Charles Herbert Best repeated the work of Von Mering and Minkowski, and went further to demonstrate they could reverse induced diabetes in dogs by giving them an extract from the pancreatic islets of Langerhans of healthy dogs. The islets of Langerhans was discovered in 1869 by an anatomist named Paul Langerhans. He identified the keys cells in the pancreas which produce the main substance that controls glucose levels in the body. Banting, Best, and colleagues (especially the chemist Collip) went on to purify the hormone insulin from bovine pancreases at
Karataş Islets material from the islets were used. Karataş Islets Karataş Islets are two Mediterranean islets in Turkey. The islands face Karataş ilçe (district) of Adana Province at and .Their distance to Karataş is less than . The area of the western islet is about and the area of the eastern islet is about . According to the municipality of Karataş these two islets were named "Didimae" in the antiquity. Currently, the islands are uninhabited. But, the ruins around the islets show that these islets were inhabited in the antiquity. According to the researcher İsa Besiç, during the construction of some 19th-century