Apparent mineralocorticoid excess syndrome cases recorded worldwide. Liquorice consumption may also cause a temporary form of AME due to its ability to block 11β-hydroxysteroid dehydrogenase type 2, in turn causing increased levels of cortisol. Cessation of licorice consumption will reverse this form of AME. Apparent mineralocorticoid excess syndrome Apparent mineralocorticoid excess (AME) is an autosomal recessive disorder causing hypertension (high blood pressure) and hypokalemia (abnormally low levels of potassium). It was found by Dr Maria I. New at Weil Cornell Hospital in New York City. It results from mutations in the "HSD11B2" gene, which encodes the kidney isozyme of 11β-hydroxysteroid dehydrogenase type 2. In
The Foolish Old Man Removes the Mountains The Foolish Old Man Removes the Mountains The Foolish Old Man Removes the Mountains () is a well-known fable from Chinese mythology about the virtues of perseverance and willpower. The tale first appeared in Book 5 of the "Liezi", a Daoist text of the 4th century BC, and was retold in the "Garden of Stories" by the Confucian scholar Liu Xiang in the 1st century BC. It was also used by Mao Zedong in a famous speech in 1945. The myth concerns a Foolish Old Man of 90 years who lived near a pair of mountains (given in some tellings