Tendon the presence of denatured collagen are factors that are believed to cause weakening of the tendon ECM and an increase in the potential for another rupture to occur. In response to repeated mechanical loading or injury, cytokines may be released by tenocytes and can induce the release of MMPs, causing degradation of the ECM and leading to recurring injury and chronic tendinopathies. A variety of other molecules are involved in tendon repair and regeneration. There are five growth factors that have been shown to be significantly upregulated and active during tendon healing: insulin-like growth factor 1 (IGF-I), platelet-derived growth factor
Schilling tendon procedure the surgery to be able to pitch for the Boston Red Sox in Game 6 of the 2004 American League Championship Series and Game 2 of the 2004 World Series. Schilling tendon procedure The Schilling tendon procedure is a temporary surgical procedure developed by the former Boston Red Sox team physician William Morgan, MD to stabilize the peroneus brevis tendon so that it is prevented from anterior displacement during ankle eversion. If the peroneal retinaculum is torn, the peroneal tendons are no longer stabilized. This allows the peroneus brevis tendon to move untethered over the lateral malleolus, creating pain. During