Antibiotic synergy with enterococcal endocarditis experienced a high relapse rate when penicillin G alone was used for treatment and a demonstrably lower relapse rate when streptomycin was combined with penicillin G to combat the infection. Since that time the research community has conducted numerous studies regarding the effects and possibilities of antibiotic combinations. Today, combination therapy is recognized as providing a broad spectrum of antibiotic coverage, effectively fighting polymicrobial infections, minimizing selection for antibiotic resistant strains, lowering dose toxicity where applicable, and in some cases providing synergistic activity. Antibiotic synergy is desirable in a clinic sense for several reasons. At the patient
Antibiotic Resistance Lab Network Antibiotic Resistance Lab Network The Antibiotic Resistance Lab Network (ARLN) is a group of laboratories of the United States Centers for Disease Control and Prevention established to supplement the work of local and state public health laboratories in the identification and research of antibiotic resistance. It was created as part of the CDC's "National Action Plan for Combating Antibiotic Resistant Bacteria". The network is part of the National Center for Emerging and Zoonotic Infectious Diseases. Laboratories in this network cover seven regions and are located in Maryland, Minnesota, New York, Tennessee, Texas, Washington, and Wisconsin, as part of their state