Chemical ionization source, the reagent gas is present in large excess compared to the analyte. Electrons entering the source with energy around 200-500 eV will preferentially ionize the reagent gas. Then, the ion/molecule reactions produces more stable reagent ions and the resultant collisions with other reagent gas molecules will create an ionization plasma. Positive and negative ions of the analyte are formed by reactions with this plasma. The following reactions are possible with methane as the reagent gas. If ammonia is the reagent gas, For isobutane as the reagent gas, Self chemical ionization is possible if the reagent ion is an ionized
Negative number the rules of signs for expanding the multiplication formula_3, and al-Karaji wrote in his "al-Fakhrī" that "negative quantities must be counted as terms". In the 10th century, Abū al-Wafā' al-Būzjānī considered debts as negative numbers in "A Book on What Is Necessary from the Science of Arithmetic for Scribes and Businessmen". By the 12th century, al-Karaji's successors were to state the general rules of signs and use them to solve polynomial divisions. As al-Samaw'al writes: the product of a negative number — "al-nāqiṣ" — by a positive number — "al-zāʾid" — is negative, and by a negative number is positive.