Transgender hormone therapy (male-to-female) medical professional. Inducers of CYP3A4 and other cytochrome P450 enzymes can reduce the effects of MTF HRT. A variety of different sex-hormonal medications are used in feminizing hormone therapy for transgender women. These include estrogens to induce feminization and suppress testosterone levels; antiandrogens such as androgen receptor antagonists, antigonadotropins, GnRH modulators, and 5α-reductase inhibitors to further oppose the effects of androgens like testosterone; and progestogens for various possible though uncertain benefits. Estrogens are the major sex hormones in women, and are responsible for the development and maintenance of feminine secondary sexual characteristics, such as breasts, wide hips, and a feminine
Causes of sexual violence use of sexual violence, including as a tactic of war to humiliate, dominate, instil fear in, disperse and/or forcibly relocate civilian members of a community or ethnic group." Refugees and internally displaced people who flee their homes during war and major disasters can experience human trafficking for sexual or labour exploitation due to the breakdown of economies and law and order. Speaking at the UN General Assembly in 2010, the UN Special Rapporteur on Violence Against Women, its Causes and Consequences noted women’s particular vulnerability and increased risk of experiencing violence following disasters. Following the 2010 Haiti earthquake, large numbers