Recreational drug use are caused by an excessive response of the body to allergens, such as the pollen released by grasses and trees. An allergic reaction causes release of histamine by the body. Other uses of antihistamines are to help with normal symptoms of insect stings even if there is no allergic reaction. Their recreational appeal exists mainly due to their anticholinergic properties, that induce anxiolysis and, in some cases such as diphenhydramine, chlorpheniramine, and orphenadrine, a characteristic euphoria at moderate doses. High dosages taken to induce recreational drug effects may lead to overdoses. Antihistamines are also consumed in combination with alcohol, particularly
Juniperus virginiana female), 'Goldspire' (narrow conical with yellow foliage), and 'Kobold' (dwarf). Some cultivars previously listed under this species, notably 'Skyrocket', are actually cultivars of "J. scopulorum". In the Missouri, Oklahoma and Arkansas Ozarks, eastern juniper is commonly used as a Christmas tree. The pollen is a known allergen, although not as potent as that of the related "Juniperus ashei" (Ashe juniper), which sheds pollen a month earlier. People allergic to one are usually allergic to both. "J. virginiana" sheds pollen as early as late winter and through early spring. Consequently, what begins as an allergy to Ashe juniper in the winter