Pharmacokinetics of progesterone concentrations was around 4 hours and the elimination half-life was in the range of 30 to 40 hours. The venous blood levels observed were very low. Because progesterone is a lipophilic and hydrophobic compound, it is not absorbed efficiently by the skin. Moreover, because the body produces about 25 mg progesterone per day on average during the luteal phase, around 50% of the body would need to be used as a surface of absorption to deliver a similar quantity of progesterone. As such, the transdermal route cannot easily achieve adequate circulating progesterone levels, and this makes transdermal progesterone impractical for
Menstrual cup investigated whether silicone menstrual cups are a viable alternative to tampons and found that approximately 91% of women in the menstrual cup group said they would continue to use the cup and recommend it to others. In a 1991 clinical study involving 51 women, 23 of the participants (45%) found rubber menstrual cups to be an acceptable way of managing menstrual flow. In a randomized controlled feasibility study in rural western Kenya, adolescent primary school girls were provided with menstrual cups or sanitary pads instead of traditional menstrual care items of cloth or tissue. Girls provided with menstrual cups had