Scar muscular power and possibly heart failure. However, there are some tissues (e.g. bone) that can heal without any structural or functional deterioration. All scarring is composed of the same collagen as the tissue it has replaced, but the composition of the scar tissue, compared to the normal tissue, is different. Scar tissue also lacks elasticity unlike normal tissue which distributes fiber elasticity. Scars differ in the amounts of collagen overexpressed. Labels have been applied to the differences in overexpression. Two of the most common types are hypertrophic and keloid scarring, both of which experience excessive stiff collagen bundled growth overextending
Neural tissue engineering into the injury site, delivering morphogens to the injury site, or growing neural tissue "in vitro" with neural stem or progenitor cells in a 3D scaffold. Proposed use of electrospun polymeric fibrous scaffolds for neural repair substrates dates back to at least 1986 in a NIH SBIR application from Simon. For the PNS, a severed nerve can be reconnected and reinnervated using grafts or guidance of the existing nerve through a channel. Recent research into creating miniature cortexes, known as corticopoiesis, and brain models, known as cerebral organoids, are techniques that could further the field of neural tissue regeneration. The