Insulin (medication) testing and occasionally skin biopsy. First line therapy against insulin hypersensitivity reactions include symptomatic therapy with antihistamines. The affected persons are then switched to a preparation that does not contain the specific agent they are reacting to or undergo desensitization. Insulin is an endogenous hormone, which is produced by the pancreas. The insulin protein has been highly conserved across evolutionary time, and is present in both mammals and invertebrates. The insulin/insulin-like growth factor signalling pathway (IIS) has been extensively studied in species including nematode worms (e.g."C. elegans"), flies ("Drosophila melanogaster") and mice ("Mus musculus"). Its mechanisms of action are highly
Insulin shock therapy recent films include "Frances" (1982) in which actress Frances Farmer undergoes insulin shock treatment, and "A Beautiful Mind", which depicted genius John Nash undergoing insulin treatment. In an episode of the medical drama "House_M.D.", Dr. House puts himself in an insulin shock to try to make his hallucinations disappear. Insulin shock therapy Insulin shock therapy or insulin coma therapy (ICT) was a form of psychiatric treatment in which patients were repeatedly injected with large doses of insulin in order to produce daily comas over several weeks. It was introduced in 1927 by Austrian-American psychiatrist Manfred Sakel and used extensively in