Tympanic cavity Tympanic cavity The tympanic cavity is a small cavity surrounding the bones of the middle ear. Within it sit the ossicles, three small bones that transmit vibrations used in the detection of sound. On its lateral surface, it abuts the external auditory meatus [ ear canal ] from which it is separated by the tympanic membrane (eardrum). The tympanic cavity is bounded by: It is formed from the tubotympanic recess, an expansion of the first pharyngeal pouch. If damaged, the tympanic membrane can be repaired in a procedure called tympanoplasty. Should fluid accumulate within the middle ear as the result
Translocase of the inner membrane modified complex containing Tim12, on the outer surface of the TIM22 complex. Tim12 is membrane bound and thus may act as a linker molecule docking Tim9 and Tim10 to the face of the TIM22 complex. The carrier preprotein is then inserted into the inner mitochondrial membrane in a potential-dependent fashion. The membrane potential is necessary for both insertion of the precursor into the carrier translocase and lateral release of the protein into the lipid phase of the inner mitochondrial membrane, which completes protein translocation. However this membrane potential-dependent process takes place in absence of ATP-driven machinery. TIM17A; TIMM17A; TIMM17B; TIMM22;