Vision in fishes layers of other neurons before it reaches them. The retina contains rod cells and cone cells. Within the retina, rod cells provide high visual sensitivity (at the cost of acuity), being used in low light conditions. Cone cells provide higher spatial and temporal resolution than rods can, and allow for the possibility of colour vision by comparing absorbances across different types of cones which are more sensitive to different wavelengths. The ratio of rods to cones depends on the ecology of the fish species concerned, "e.g.", those mainly active during the day in clear waters will have more cones than
Gene therapy of the human retina ability to target cone photoreceptors. The vertebrate neural retina composed of several layers and distinct cell types (see anatomy of the human retina). A number of these cell types are implicated in retinal diseases, including retinal ganglion cells, which degenerate in glaucoma, the rod and cone photoreceptors, which are responsive to light and degenerate in retinitis pigmentosa, macular degeneration, and other retinal diseases, and the retinal pigment epithelium (RPE), which supports the photoreceptors and is also implicated in retinitis pigmentosa and macular degeneration. In retinal gene therapy, AAV is capable of "transducing" these various cell types by entering the cells