Valerian (herb) particular binding site. Hydrophilic extractions of the herb commonly sold over the counter, however, probably do not contain significant amounts of isovaltrate. Valerenic acid in valerian stimulates serotonin receptors as a partial agonist, including 5-HT which is implicated in the sleep-wake cycle. The chief constituent of valerian is a yellowish-green to brownish-yellow oil present in the dried root, varying in content from 0.5 to 2.0%. This variation in quantity may be determined by location; a dry, stony soil yields a root richer in oil than moist, fertile soil. The volatile oils that form the active ingredient are pungent, somewhat reminiscent
Valerian (emperor) of Lactantius, Shapur I sent Valerian and some of his army to the city of Bishapur or Gundishapur where they lived in relatively good conditions. Shapur used the remaining soldiers in engineering and development plans. "Band-e Kaisar" (Caesar's dam) is one of the remnants of Roman engineering located near the ancient city of Susa. In all the stone carvings on Naghshe-Rostam, in Iran, Valerian is represented holding hands with Shapur I, a sign of submission. According to the early Persian Muslim scholar Abu Hanifa Dinawari, Shapur settled the prisoners of war in Gundishapur and released Valerian, as promised, after the