Origin of the domestic dog matched across Eurasia and its branch is phylogenetically rooted in the same sequence as the Altai dog (not a direct ancestor). The subclade d2 hybrid haplotypes are found in 2.6% of South-West Asian dogs. Haplogroup E: Derived from post-domestication wolf–dog hybridization in East Asia, (rare distribution in South-East Asia, Korea and Japan). Haplogroup F: Derived from post-domestication wolf–dog hybridization in Japan. A study of 600 dog specimens found only one dog whose sequence indicated hybridization with the extinct Japanese wolf. It is not known whether this hybridization was the result of humans selecting for phenotypic traits from local wolf populations
Origin of the domestic dog agriculture, which was approximately 10,000 years before present (YBP). The earlier association of dogs with humans may have allowed dogs to have a profound influence on the course of early human history and the development of civilization. However, the timing, geographic locations, and ecological conditions that led to dog domestication are not agreed. Genetic studies indicate that the gray wolf is the closest living relative of the dog, with no evidence of any other canine species having contributed. Attempting to reconstruct the dog's lineage through the phylogenetic analysis of DNA sequences from modern dogs and wolves has given conflicting results