Tendon the presence of denatured collagen are factors that are believed to cause weakening of the tendon ECM and an increase in the potential for another rupture to occur. In response to repeated mechanical loading or injury, cytokines may be released by tenocytes and can induce the release of MMPs, causing degradation of the ECM and leading to recurring injury and chronic tendinopathies. A variety of other molecules are involved in tendon repair and regeneration. There are five growth factors that have been shown to be significantly upregulated and active during tendon healing: insulin-like growth factor 1 (IGF-I), platelet-derived growth factor
What She Is (Is a Woman in Love) What She Is (Is a Woman in Love) "What She Is (Is a Woman in Love)" is a song written by Bob McDill and Paul Harrison and recorded by American country music artist Earl Thomas Conley. It was released in February 1988 as the lead single from the album, "The Heart of It All". The song was Earl Thomas Conley's fifteenth number one on the country chart. The single went to number one for one week and spent a total of thirteen weeks on the country chart. "What She Is (Is a Woman in Love)" debuted on the U.S. "Billboard"