Antibiotic resistance in gonorrhea mechanism for beta-lactam resistance. There have been over 200 beta-lactamases described and some of them are antibiotic specific. TEM-1 is a penicillinase specific for penicillins. This enzyme will bind to the beta-lactam ring which is a structural characteristic for beta-lactams and hydrolyze the ring. This renders the antibiotic inactive. The spread of the penicillinase resistance was much faster compared to the chromosomal-mediated resistance mechanisms. The plasmids containing TEM-1 could be passed from bacterium to bacterium via conjugation Quinolones are a class of synthetic antibiotics that inhibit DNA replication, recombination, and repair by interacting with the bacterial DNA gyrase and/or topoisomerase
This Was Supposed to Be the Future Johnny Tarr." This Was Supposed to Be the Future This Was Supposed to Be the Future is the third studio album by The Nextmen. It was released in June 2007 on Antidote Records. It was a change in their sound; a prevalence of songs over rap tracks. Ten different vocalists appear on the album. Zarif appears the most, with three tracks, and LSK and Dynamite MC both appear twice. The first single was "Let It Roll", featuring Alice Russell. The second single was "Something Got You", featuring singer-songwriter Zarif. At their album launch, The Nextmen performed as a full 10