Muscarinic antagonist brain, involving both increased levels of acetylcholine and degeneration of dopaminergic pathways (nigrostriatal pathway). Thus, in parkinsonism there is decreased level of dopaminergic activity. One method of balancing the neurotransmitters is through blocking central cholinergic activity using muscarinic receptor antagonists. Atropine acts on the M2 receptors of the heart and antagonizes the activity of acetylcholine. It causes tachycardia by blocking vagal effects on the sinoatrial node. Acetylcholine hyperpolarizes the sinoatrial node, which is overcome by MRA and thus increases the heart rate. If atropine is given by intramuscular or subcutaneous injection, it causes initial bradycardia. This is because by i.m/s.c
Node graph architecture in which a number of input images have been layered. By connecting many different node types together complex image effects can be produced. The node graph architecture often allows grouping of nodes inside other group nodes. This hides complexity inside of the group nodes, and limits their coupling with other nodes outside the group. This leads to a hierarchy where smaller graphs are embedded in group nodes. In Nuke the group node is simply called the Group node. In the paper Hierarchical Small Worlds in Software Architecture they argue that most large software systems are built in a modular and