Protein signalling in heart development Protein signalling in heart development The heart is the first functional organ in a vertebrate embryo. There are 5 stages to heart development. Specification of cardiac precursor cells: The lateral plate mesoderm delaminates to form two layers: the dorsal somatic (parietal) mesoderm and the ventral splanchnic (visceral) mesoderm. The heart precursor cells come from the two regions of the splanchnic mesoderm called the cardiogenic mesoderm. These cells can differentiate into endocardium which lines the heart chamber and valves and the myocardium which forms the musculature of the ventricles and the atria. The heart cells are specified in anterior mesoderm by
How Many Drinks? How Many Drinks? "How Many Drinks?" is a song by American recording artist Miguel, taken from his critically acclaimed second studio album, "Kaleidoscope Dream". The song was produced by Salaam Remi. A remixed single featuring Kendrick Lamar on an added third verse was released as the album's third single on March 3, 2013. It received a nomination for Best R&B Performance at the 56th Grammy Awards held in January 2014. The music video, directed by Clark Jackson, was released on April 22, 2013 on VEVO. The song debuted at 88 on the "Billboard" Hot 100 on week ending May 4,