Grünenthal prohibited the research and manufacture of penicillin by German companies. When the ban was lifted, Grünenthal was the first company to introduce penicillin in the postwar period into the German market. This investment achieved a big financial boost for the company. Chemie Grünenthal synthesized thalidomide in 1954 and acquired a 20-year patent. Soon after obtaining a patent in April 1954, the company started clinical trials, and as early as November 1956, marketed the drug for the treatment of respiratory infections under the trade name Grippex, a combination drug that contained thalidomide, quinine, vitamin C, phenacetin, and acetylsalicylic acid. Researchers at
Should Have Known Better shroud into a tender lyric about shoving aside his fear, discovering an oasis of perspective when he looks to his brother’s newborn daughter and sees his mother in her face. When he sings 'nothing can be changed,' he doesn’t sound resigned, but ready to look forward. It’s the dawn at the end of a long night, a prayer that past traumas might be healed by a beautiful present." Should Have Known Better "Should Have Known Better" is a song by American singer-songwriter and multi-instrumentalist Sufjan Stevens. It is the second track and second single from his seventh studio album, "Carrie