Nonsteroidal anti-inflammatory drug more effective than salicin and, in addition to its fever-reducing properties, is anti-inflammatory and analgesic. In 1869, Hermann Kolbe synthesised salicylate, although it was too acidic for the gastric mucosa. The reaction used to synthesise aromatic acid from a phenol in the presence of CO2 is known as the Kolbe-Schmitt reaction. By 1897 the German chemist Felix Hoffmann and the Bayer company prompted a new age of pharmacology by converting salicylic acid into acetylsalicylic acid—named aspirin by Heinrich Dreser. Other NSAIDs were developed from the 1950s forward. In 2001, NSAIDs accounted for 70,000,000 prescriptions and 30 billion over-the-counter doses sold
Acid test (gold) to assess the liquidity of a business. The use of the term "acid test" for experiences with the psychedelic drug LSD was popularised by the Merry Pranksters, and derives from the drug's common name, "acid". Acid test (gold) An acid test is any qualitative chemical or metallurgical assay which uses acid; most commonly, and historically, the use of a strong acid to distinguish gold from base metals. Figuratively, acid test is any definitive test for some attribute, e.g. of a person's character, or of the performance of product. Testing for gold with acid focuses on the fact that gold is