Blood gas tension constant 0.0031 represents the amount of oxygen dissolved in plasma. The dissolved-oxygen term is generally small relative to the term for hemoglobin-bound oxygen, but becomes significant at very high PO (as in a hyperbaric chamber) or in severe anemia. This is an estimation and does not account for differences in temperature, pH and concentrations of 2,3 DPG. Blood gas tension Blood gas tension refers to the partial pressure of gases in blood. There are several significant purposes for measuring gas tension; the most common gas tensions measured are oxygen tension (PO), the carbon dioxide tension (PCO) and carbon monoxide tension
Glycated hemoglobin the degree of control of glucose metabolism in diabetic patients was proposed in 1976 by Anthony Cerami, Ronald Koenig and coworkers. Glycated hemoglobin causes an increase of highly reactive free radicals inside blood cells. Radicals alter blood cell membrane properties. This leads to blood cell aggregation and increased blood viscosity which results in impaired blood flow. Another way glycated Hb causes damage is via inflammation which results in atherosclerotic plaque (atheroma) formation. Free radical build-up promotes the excitation of Fe-Hb through into abnormal ferryl Hb (Fe-Hb). Fe is unstable and reacts with specific amino acids in Hb to regain its