Photopsin absorb light at different wavelengths as retinal-bound pigments. Humans have three different photoreceptor proteins ("photopsin" or "cone opsins") which are found in cone cells and which are responsible for colour vision: George Wald received the 1967 Nobel Prize in Physiology or Medicine for his experiments in the 1950s that showed the difference in absorbance by these photopsins (see image). Photopsin Photopsins (also known as Cone opsins) are the photoreceptor proteins found in the cone cells of the retina that are the basis of color vision. Iodopsin, the cone pigment system in chicken retina, is a close analog of the "visual
Retina of the retina. Recombinant adeno-associated virus (rAAV) vectors possess a number of features that render them ideally suited for retinal gene therapy, including a lack of pathogenicity, minimal immunogenicity, and the ability to transduce postmitotic cells in a stable and efficient manner. rAAV vectors are increasingly utilized for their ability to mediate efficient transduction of retinal pigment epithelium (RPE), photoreceptor cells and retinal ganglion cells. Each cell type can be specifically targeted by choosing the appropriate combination of AAV serotype, promoter, and intraocular injection site. Several clinical trials have already reported positive results using rAAV to treat Leber's congenital amaurosis,