Protein signalling in heart development Protein signalling in heart development The heart is the first functional organ in a vertebrate embryo. There are 5 stages to heart development. Specification of cardiac precursor cells: The lateral plate mesoderm delaminates to form two layers: the dorsal somatic (parietal) mesoderm and the ventral splanchnic (visceral) mesoderm. The heart precursor cells come from the two regions of the splanchnic mesoderm called the cardiogenic mesoderm. These cells can differentiate into endocardium which lines the heart chamber and valves and the myocardium which forms the musculature of the ventricles and the atria. The heart cells are specified in anterior mesoderm by
How Many Licks? "a celebration of autonomous female sexuality" to a "vulgar, demeaning moment of black female objectification". Some critics compared "How Many Licks?" to Trinidadian-American rapper Nicki Minaj's 2014 single, "Anaconda". Alex Kristelis of "Bustle" noted that both songs focused on men's appreciation of the singer's body. A "Khaleej Times" writer called "Anaconda" a "blatant copy" of "How Many Licks?", with Minaj's song sharing "the lyrical blue print and theme" of Lil' Kim's. "Westword"'s Cory Lamz wrote that Minaj parodied "How Many Licks?" and its associated visuals in the music video for her 2011 single "Stupid Hoe". According to Michael Arceneaux, "How