Basal metabolic rate be elevated in stress, illness, and diabetes. Menopause may also affect metabolism. Heart rate is determined by the medulla oblongata and part of the pons, two organs located inferior to the hypothalamus on the brain stem. Heart rate is important for basal metabolic rate and resting metabolic rate because it drives the blood supply, stimulating the Krebs cycle. During exercise that achieves the anaerobic threshold, it is possible to deliver substrates that are desired for optimal energy utilization. The anaerobic threshold is defined as the energy utilization level of heart rate exertion that occurs without oxygen during a standardized test
Brain of the soul lies in the brain or heart. Aristotle favored the heart, and thought that the function of the brain was merely to cool the blood. Democritus, the inventor of the atomic theory of matter, argued for a three-part soul, with intellect in the head, emotion in the heart, and lust near the liver. The unknown author of "On the Sacred Disease", a medical treatise in the Hippocratic Corpus, came down unequivocally in favor of the brain, writing: The Roman physician Galen also argued for the importance of the brain, and theorized in some depth about how it might