Dark skin gives seven to eightfold protection against DNA damage, but even the darkest skin colour cannot protect against all damage to DNA. Dark skin offers great protection against UVR because of its eumelanin content, the UVR-absorbing capabilities of large melanosomes, and because eumelanin can be mobilized faster and brought to the surface of the skin from the depths of the epidermis. For the same body region, light- and dark-skinned individuals have similar numbers of melanocytes (there is considerable variation between different body regions), but pigment-containing organelles, called melanosomes, are larger and more numerous in dark-skinned individuals. Keratocytes from dark skin cocultured
Diarylide pigment with the same coupling partners. The molecular structures of these molecules is more conjugated than represented in the images shown below. The pigments' colors can range from yellow to green. One of the most common diarylide yellow pigments is Pigment Yellow 12. Its CAS number is . Other diarylide yellow pigments include ‘’’yellow 13’’’ , ‘’’yellow 17’’’ and ‘’’yellow 83’’’ . These pigments share the same backbone and vary in color depending on substitution of the benzene rings. Worldwide production of color organic pigments was estimated to be about 250,000 metric tons (t) in 2006, with about 25%, or 62,500