Organ procurement of kidneys is a relatively widespread practice. For the heart normothermic preservation has been used in which the heart is provided with warm oxygenated blood and so continues to beat ex-vivo during its preservation. This technique has also been applied to lungs and led to the emergence of donor lung reconditioning centres in North America. For the liver, hypothermic and normothermic techniques are being used with evidence to suggest that both may be beneficial . The HOPE (HIV Organ Policy Equity) Act allows for clinical research on organ transplantation from HIV+ donors to HIV+ recipients. The Act was passed by
Base excess data. The term and concept of base excess were first introduced by Poul Astrup and Ole Siggaard-Andersen in 1958. Base excess can be estimated from the bicarbonate concentration ([HCO]) and pH by the equation: formula_1 with units of mEq/L. The same can be alternatively expressed as formula_2 Calculations are based on the Henderson-Hasselbalch equation: Ultimately the end result is: Base excess beyond the reference range indicates Blood pH is determined by both a metabolic component, measured by base excess, and a respiratory component, measured by PaCO (partial pressure of carbon dioxide). Often a disturbance in one triggers a partial compensation