Pacemaker current on hyperpolarization, and very slow kinetics. The funny current is highly expressed in spontaneously active cardiac regions, such as the sinoatrial node (SAN, the natural pacemaker region), the atrioventricular node (AVN) and the Purkinje fibres of conduction tissue. The funny current is a mixed sodium–potassium current that activates upon hyperpolarization at voltages in the diastolic range (normally from −60/−70 mV to −40 mV). When, at the end of a sinoatrial action potential, the membrane repolarizes below the I threshold (about −40/−50 mV), the funny current is activated and supplies inward current, which is responsible for starting the diastolic depolarization phase
Exposed node problem Exposed node problem In wireless networks, the exposed node problem occurs when a node is prevented from sending packets to other nodes because of a neighboring transmitter. Consider an example of 4 nodes labeled R1, S1, S2, and R2, where the two receivers (R1, R2) are out of range of each other, yet the two transmitters (S1, S2) in the middle are in range of each other. Here, if a transmission between S1 and R1 is taking place, node S2 is prevented from transmitting to R2 as it concludes after carrier sense that it will interfere with the transmission by