Tendon the presence of denatured collagen are factors that are believed to cause weakening of the tendon ECM and an increase in the potential for another rupture to occur. In response to repeated mechanical loading or injury, cytokines may be released by tenocytes and can induce the release of MMPs, causing degradation of the ECM and leading to recurring injury and chronic tendinopathies. A variety of other molecules are involved in tendon repair and regeneration. There are five growth factors that have been shown to be significantly upregulated and active during tendon healing: insulin-like growth factor 1 (IGF-I), platelet-derived growth factor
Tendon-driven robot models and tools for simulation control, data acquisition and system investigation. The Anatomically Correct Testbed robotic hand uses tendons and woven finger extensor hoods to capture the biomechanical properties of the human hand. The tendons slide over 3D printed bones matching human bone shapes, reproducing the variable moment arms and some of the tendon network interactions found in the human hand. The tendons are actuated by direct drive (without gearing), allowing them to spool out freely when other tendons oppose them in the skeleton. Tendon-driven robot Tendon-driven robots (TDR) are robots whose limbs mimic biological musculoskeletal systems. They use plastic