Tetrapod probably had a three-chambered heart, as do modern amphibians and reptiles, in which oxygenated blood from the lungs and de-oxygenated blood from the respiring tissues enters by separate atria, and is directed via a spiral valve to the appropriate vessel — aorta for oxygenated blood and pulmonary vein for deoxygenated blood. The spiral valve is essential to keeping the mixing of the two types of blood to a minimum, enabling the animal to have higher metabolic rates, and be more active than otherwise. The difference in density between air and water causes smells (certain chemical compounds detectable by chemoreceptors) to
Portal vein thrombosis of infection such as fever, chills, night sweats may be present. Causes can include pancreatitis, cirrhosis, diverticulitis, and cholangiocarcinoma. It is also a known complication of surgical removal of the spleen. The diagnosis of portal vein thrombosis is usually made by ultrasound, computed tomography with contrast or magnetic resonance imaging. D-dimer levels in the blood may be elevated as a result of fibrin breakdown. Treatments include anticoagulants, shunts, bypass surgery, and transplants. Portal vein thrombosis Portal vein thrombosis is a form of venous thrombosis affecting the hepatic portal vein, which can lead to portal hypertension and reduction in the blood