Origin of the domestic dog matched across Eurasia and its branch is phylogenetically rooted in the same sequence as the Altai dog (not a direct ancestor). The subclade d2 hybrid haplotypes are found in 2.6% of South-West Asian dogs. Haplogroup E: Derived from post-domestication wolf–dog hybridization in East Asia, (rare distribution in South-East Asia, Korea and Japan). Haplogroup F: Derived from post-domestication wolf–dog hybridization in Japan. A study of 600 dog specimens found only one dog whose sequence indicated hybridization with the extinct Japanese wolf. It is not known whether this hybridization was the result of humans selecting for phenotypic traits from local wolf populations
Ticks of domestic animals create a potentially fatal inflammatory crisis of the blood. The name redwater (coloured urine) derives from the hemoglobinuria caused by the destruction of red blood cells infected with the merozoite stage of "Babesia"; anemia results from the same destruction. Horses suffer babesiosis or biliary fever when infected by "Ba. equi" or "B. caballi". This occurs in many countries where vector ticks are found, such as "R. e. evertsi", "Hy. truncatum", and "D. nitens". Dogs are at risk from severe infection with "Ba. canis" and its subspecies, transmitted by the dog ticks "R. sanguineus", "D. reticulatus", and "Ha. leachi". Domestic cats