Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
A Is for Acid A Is for Acid A Is for Acid is a 2002 British television film based on the life of the serial killer John George Haigh, known as the Acid Bath Murderer, because he dissolved the bodies of six people in sulphuric acid. Haigh, hanged in 1949 for his crimes, had wrongly believed that murder could not be proven without the presence of a body. Starring Martin Clunes in the lead role, the film was shot in Scarborough, chosen because its appearance was believed similar to that of London when Haigh lived there during the 1940s. The film was produced by