Β-lactam antibiotic reactions to any β-lactam antibiotic may occur in up to 10% of patients receiving that agent (a small fraction of which are truly IgE-mediated allergic reactions, see amoxicillin rash). Anaphylaxis will occur in approximately 0.01% of patients. There is perhaps a 5%-10% cross-sensitivity between penicillin-derivatives, cephalosporins, and carbapenems; but this figure has been challenged by various investigators. Nevertheless, the risk of cross-reactivity is sufficient to warrant the contraindication of all β-lactam antibiotics in patients with a history of severe allergic reactions (urticaria, anaphylaxis, interstitial nephritis) to any β-lactam antibiotic. A Jarisch–Herxheimer reaction may occur after initial treatment of a spirochetal
Who I Was Born to Be to Be" was composed by Johan Fransson, Tim Larsson, and Tobias Lundgren. Among her most notable performances of "Who I Was Born to Be", Boyle's first live performance of this song was on 7 December 2009 in London before an audience for the taping of her television special "". "Who I Was Born to Be" was used as the theme song for the anime "Welcome to the Space Show" which was released in 2010. Boyle performed the song on The Oprah Winfrey Show in Chicago on 19 January 2010. On 10 July 2011 she performed it in front of a