Nav1.5 kb. The gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5’ untranslated region (5’UTR) and exon 28 the 3’ untranslated region (3’UTR) of the RNA. SCN5A is part of a family of 10 genes that encode different types of sodium channels, i.e. brain-type (Na1.1, Na1.2, Na1.3, Na1.6), neuronal channels (Na1.7, Na1.8 and Na1.9), skeletal muscle channels (Na1.4) and the cardiac sodium channel Na1.5. SCN5A is mainly expressed in the heart, where expression is abundant in working myocardium and conduction tissue. In contrast, expression is low in the sinoatrial node and atrioventricular node.
Node B Node B Node B is the telecommunications node in particular mobile communication networks, namely those that adhere to the UMTS standard. The Node B provides the connection between mobile phones (UEs) and the wider telephone network. UMTS is the dominating 3G standard. Node B corresponds to BTS (base transceiver station) in GSM. This is the hardware that is connected to the mobile phone network that communicates directly with mobile handsets. In contrast with GSM base stations, Node B uses WCDMA/TD-SCDMA as the air interface technology. As in all cellular systems, such as UMTS and GSM, the Node B contains radio