Tendon induce endothelial cell proliferation and migration, and VEGF mRNA has been shown to be expressed at the site of tendon injuries along with collagen I mRNA. Bone morphogenetic proteins (BMPs) are a subgroup of TGF-β superfamily that can induce bone and cartilage formation as well as tissue differentiation, and BMP-12 specifically has been shown to influence formation and differentiation of tendon tissue and to promote fibrogenesis. In animal models, extensive studies have been conducted to investigate the effects of mechanical strain in the form of activity level on tendon injury and healing. While stretching can disrupt healing during the initial
Tendon-driven robot Tendon-driven robot Tendon-driven robots (TDR) are robots whose limbs mimic biological musculoskeletal systems. They use plastic straps to mimic muscles and tendons. Such robots are claimed to move in a "more natural" way than traditional robots that use rigid metal or plastic limbs controlled by geared actuators. TDRs can also help understand how biomechanics relates to embodied intelligence and cognition. Challenges include effectively modeling the human body’s complex motions and ensuring accurate positioning, given that the tendons are prone to stretch, which costs them strength and smooth operation. TDRs are the subject of considerable research and commercial systems followed. Myorobotics