Nirenberg and Leder experiment acid. Oswald Avery discovered that the substance responsible for producing inheritable change in the disease-causing bacteria was neither a protein nor a lipid, rather deoxyribonucleic acid (DNA). He and his colleagues Colin MacLeod and Maclyn McCarty suggested that DNA was responsible for transferring genetic information. Later, Erwin Chargaff discovered that the makeup of DNA differs from one species to another. These experiments helped pave the way for the discovery of the structure of DNA. In 1953, with the help of Maurice Wilkins and Rosalind Franklin’s X-ray crystallography, James Watson and Francis Crick proposed DNA is structured as a double helix.
Raymond Gosling of x-ray diffraction photography of DNA and obtained at the time the sharpest diffraction images of DNA. Gosling made the X-ray diffraction image of DNA known as "Photograph 51". This work led directly to the 1962 Nobel Prize for Physiology or Medicine being awarded to Francis Crick, James D. Watson and Maurice Wilkins. Gosling was the co-author with Franklin of one of the three DNA double helix papers published in "Nature" in April 1953. His other King's colleagues included Alex Stokes and Herbert Wilson. Gosling briefly remained at King's College following the completion of his thesis in 1954 before lecturing