Pituitary gland types of cells can be differentiated. The posterior lobe develops as an extension of the hypothalamus. The posterior pituitary hormones are synthesized by cell bodies in the hypothalamus. The magnocellular neurosecretory cells, of the supraoptic and paraventricular nuclei located in the hypothalamus, project axons down the infundibulum to terminals in the posterior pituitary. This simple arrangement differs sharply from that of the adjacent anterior pituitary, which does not develop from the hypothalamus. The release of pituitary hormones by both the anterior and posterior lobes is under the control of the hypothalamus, albeit in different ways. The anterior pituitary synthesizes and
Pituitary adenoma only, with no other associated symptoms that occur in Multiple endocrine neoplasia Type 1 or Carney complex. FIPA was first described in a limited cohort of families by group in Liège, Belgium ; later FIPA was fully characterized in a multicenter international study of 64 families. FIPA families are divided into those that are homogenous and have the same type of pituitary adenoma in all the affected family members (e.g. only acromegaly, only prolactinoma, etc) , while heterogeneous FIPA families can have different pituitary adenomas in affected family members. FIPA has two known genetic causes, mutations in the "aryl hydrocarbon