Gonadal dysgenesis If a single or combination of these genes are mutated or deleted, downstream signalling is disrupted, leading to malformation of male external genitalia. SRY acts on gene SOX9 which drives Sertoli cell formation and testis differentiation. An absence in SRY causes SOX9 to not be expressed at the appropriate time or concentration, leading to a deficiency in testosterone and Anti-Müllerian hormone production. Inadequate levels of testosterone and Anti-Müllerian hormone disrupts the development of Wolffian ducts and internal genitalia that are key to male reproductive tract development. The lack of the male associated steroid hormones drives Müllerian duct development and perusal
Causes of sexual violence decreased the incidence of rape. Social learning theory of rape is similar to the feminist theory and links cultural traditions such as imitation, sex-violence linkages, rape myths (e.g., "women secretly desire to be raped"), and desensitization to be the core causes of rape. Rape culture is a term used within women's studies and feminism, describing a culture in which rape and other sexual violence (usually against women) are common and in which prevalent attitudes, norms, practices, and media condone, normalize, excuse, or encourage sexualized violence. Within the paradigm, acts of sexism are commonly employed to validate and rationalize normative misogynistic