Nucleated red blood cell in the normal development of a normoblast. A megaloblast is an unusually large erythroblast that can be associated with vitamin B deficiency (caused by pernicious anemia or dietary insufficiency), folic acid deficiency, or both (such anemias are collectively called megaloblastic anemias). This kind of anemia leads to macrocytes (abnormally large red cells) and the condition called macrocytosis. The cause of this cellular gigantism is an impairment in DNA replication that delays nuclear maturation and cell division. Because RNA and cytoplasmic elements are synthesized at a constant rate despite the cells' impaired DNA synthesis, the cells show nuclear-cytoplasmic asynchrony. NRB's can
White blood cell underlying cause, though the cause may not always be found. The complete blood cell count is a blood panel that includes the overall WBC count and various subsets such as the absolute neutrophil count. Reference ranges for blood tests specify the typical counts in healthy people. TLC- (Total leucocyte count): Normal TLC in an adult person is 6000-8000WBC/mm^3 of blood. DLC- (Differential leucocyte count): Number/ (%) of different type of leucocyte in per cubic mm. of blood. White blood cell White blood cells (also called leukocytes or leucocytes and abbreviated as WBCs) are the cells of the immune system that