Acetyl group known as paracetamol), and acetylsalicylic acid (better known as aspirin). The introduction of an acetyl group into a molecule is called acetylation. In biological organisms, acetyl groups are commonly transferred from acetyl-CoA to other organic molecules. Acetyl-CoA is an intermediate both in the biological synthesis and in the breakdown of many organic molecules. Acetyl-CoA is also created during the second stage of cellular respiration, the Krebs Cycle, by the action of pyruvate dehydrogenase on pyruvic acid. Histones and other proteins are often modified by acetylation. For example, on the DNA level, histone acetylation by acetyltransferases (HATs) causes an expansion of
U Should've Known Better U Should've Known Better "U Should've Known Better" is a song by American recording artist Monica. It was written in collaboration with Harold Lilly and Jermaine Dupri, and produced by the latter along with frequent co-producer Bryan Michael Cox for her original third studio album, "All Eyez on Me" (2002). When the album was shelved for release outside Japan, the song was one out of five original records that were transferred into its new version, "After the Storm" (2003). A contemporary R&B slow jam, "U Should've Known Better" contains elements of soul music and rock music. Built on an pulsating