Hemoglobin failure, or abnormal hemoglobin (such as that of sickle-cell disease). The ability of each hemoglobin molecule to carry oxygen is normally modified by altered blood pH or CO, causing an altered oxygen–hemoglobin dissociation curve. However, it can also be pathologically altered in, e.g., carbon monoxide poisoning. Decrease of hemoglobin, with or without an absolute decrease of red blood cells, leads to symptoms of anemia. Anemia has many different causes, although iron deficiency and its resultant iron deficiency anemia are the most common causes in the Western world. As absence of iron decreases heme synthesis, red blood cells in iron deficiency
Hemoglobin D-Punjab Angeles”. Hemoglobin D is the 4th most common hemoglobin variant. It developed as a response to the selective pressures of malaria in these regions of Asia. Hemoglobin is the main ingredient in red blood cells. People with hemoglobin D trait have slightly more hemoglobin A than hemoglobin D. People with Hemoglobin D trait do not have health problems related to having the trait. People with hemoglobin D trait do not have Hemoglobin D disease or sickle cell disease. They cannot develop these diseases later in life. Hemoglobin helps red blood cells carry oxygen from the lungs to other parts of