Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian Pletnev by essentially arguing for continued state subsidies fro Proletkult which were being reduced under the New Economic Policy. He praised the organisations literary output, including the role of drama as well as the development of production art. From 1933 to 1936 he was Deputy Head of the General Directorate of the Film Industry at the SNK of the USSR. However he was subsequenlty purged and shot in 1942. Valerian Pletnev Valerian Fedorovich Pletnev (1886–1942) () was a Russian revolutionary who after many years as a joiner became a playwright and activist in Proletkult, following the Russian Revolution. He joined the