Antibiotic resistance in gonorrhea bacterial cell being inhibited. There is a possibility of future enzymes (made by the bacterium) that will be able to denature and inactivate the aminoglycosides. Antibiotic resistance in gonorrhea The Gonorrhea bacterium Neisseria gonorrhoeae has developed antibiotic resistance to many antibiotics. The bacteria was first identified in 1879, although some Biblical scholars believe that references to the disease can be found as early as Parshat Metzora of the Old Testament. In the 1940s effective treatment with penicillin became available, but by the 1970s resistant strains predominated. Resistance to penicillin has developed through two mechanisms: chromasomally mediated resistance (CMRNG) and penicillinase-mediated
Antibiotic use in dentistry prophylaxis to prevent post-operative infections, resulting from bacteraemia, and infective endocarditis was practiced by dentists, especially in patients at high risk (i.e. with heart problems). However, according to new recommendations from the National Institution for Health and Care Excellence (NICE), antibiotic prophylaxis should not be offered for all patients at risk of infective endocarditis. This is due to the ever-increasing antibiotic resistance and there is no or very little evidence to show whether antibiotic prophylaxis is effective or ineffective against post-operative infections. Moreover, it is yet to be established whether the benefits of administering antibiotics prophylactically outweighs the inherent risks,