Thioglycolic acid corresponding disulfide (2-[(carboxymethyl)disulfanyl]acetic acid or dithiodiglycolic acid): Thioglycolic acid, usually as its dianion, forms complexes with metal ions. Such complexes have been used for the detection of iron, molybdenum, silver, and tin. Thioglycolic acid reacts with diethyl acetylmalonate to form acetylmercaptoacetic acid and diethyl malonate, the reducing agent in conversion of Fe(III) to Fe(II). Scientist David R. Goddard, in the early 1930s, identified TGA as a useful reagent for reducing the disulfide bonds in proteins, including keratin (hair protein), while studying why protease enzymes could not easily digest hair, nails, feathers, and such. He realized that while the disulfide bonds,
Debra Nails Debra Nails Debra Nails (born November 15, 1950) is an American philosophy professor and well known classics scholar who taught at Michigan State University. Nails earned her M.A. in philosophy and classical Greek from Louisiana State University before going on to earn a Ph.D. in philosophy at the University of the Witwatersrand, Johannesburg in 1993. Previously, she taught in the Department of Classics, Philosophy, and Religion at Mary Washington College. Nails taught courses on the history of philosophy, continental rationalism, metaphysics, and modern philosophy. Nails' work primarily focuses on ancient Greek philosophy, metaphysics, feminist philosophy, and early modern philosophy. She