Gene therapy of the human retina levels of light. What follows often is the death of cone cells, responsible for color vision and acuity, at light levels present during the day. Loss of cones leads to full blindness as early as five years old, but may not onset until many years later. There have been multiple hypotheses about how the lack of rod cells can lead to the death of cone cells. Pinpointing a mechanism for RP is difficult because there are more than 39 genetic loci and genes correlated with this disease. In an effort to find the cause of RP, there have been different
Laser safety near-infrared light onto the retina. A laser beam can be focused to an intensity on the retina which may be up to 200,000 times higher than at the point where the laser beam enters the eye. Most of the light is absorbed by melanin pigments in the pigment epithelium just behind the photoreceptors, and causes burns in the retina. Ultraviolet light with wavelengths shorter than 400 nm tends to be absorbed by lens and 300 nm in the cornea, where it can produce injuries at relatively low powers due to photochemical damage. Infrared light mainly causes thermal damage to the