Max Perutz the onset of Huntington disease is related to the number of glutamine repeats as they bind to form what he called a polar zipper. During the early 1950s, while Watson and Crick were determining the structure of deoxyribonucleic acid (DNA), they made use of unpublished X-ray diffraction images taken by Rosalind Franklin, shown at meetings and shared with them by Maurice Wilkins, and of Franklin's preliminary account of her detailed analysis of the X-ray images included in an unpublished 1952 progress report for the King's College laboratory of Sir John Randall. Randall and others eventually criticised the manner in which
Francis Crick some of which were performed by Crick. The details of the code came mostly from work by Marshall Nirenberg and others who synthesized synthetic RNA molecules and used them as templates for "in vitro" protein synthesis. Nirenberg first announced his results to a small audience in Moscow at a 1961 conference. Crick's reaction was to invite Nirenberg to deliver his talk to a larger audience. An enduring controversy has been generated by Watson and Crick's use of DNA X-ray diffraction data collected by Franklin and Wilkins. The controversy arose from the fact that some of Franklin's unpublished data were used