Neurovascular bundle fluid and blood, they tend to have large surface area and short diffusion path. Normally, capillaries consist of a central lumen lined with an endothelium, a single layer of smooth epithelial cells. In contrast, deep neurovascular bundles, with arteries in them, have a more complicated composition. Arteries are the vessels that transfer the blood pumped by the heart to the entire body. Arteries have high intraluminal blood pressure, relative to capillaries and veins. To compensate arteries have a smooth muscle and a connective tissue structure outside the endothelium. This composition allows arteries to contract/relax, be flexible under pressure, and transfer
Angiopoietin Angiopoietin Angiopoietin is part of a family of vascular growth factors that play a role in embryonic and postnatal angiogenesis. Angiopoietin signaling most directly corresponds with angiogenesis, the process by which new arteries and veins form from preexisting blood vessels. Angiogenesis proceeds through sprouting, endothelial cell migration, proliferation, and vessel destabilization and stabilization. They are responsible for assembling and disassembling the endothelial lining of blood vessels. Angiopoietin cytokines are involved with controlling microvascular permeability, vasodilation, and vasoconstriction by signaling smooth muscle cells surrounding vessels. There are now four identified angiopoietins: ANGPT1, ANGPT2, ANGPTL3, ANGPT4. In addition, there are a number