Henry Jones Shrapnell tympanic membrane is known as "Shrapnell's membrane". During the same year, Shrapnell published two other articles in the same journal, these being in regards to the function of the tympanic membrane and the nerves of the ear. In 1833, he published an article (again in the same journal) on the anatomy of the incus. Henry Jones Shrapnell Henry Jones Shrapnell (1792–1834) was an English anatomist. For a period of time during his career he was a colleague to Edward Jenner (1749-1823), creator of the vaccine for smallpox. Shrapnell is remembered for his pioneer work in otology. He was the first
Integral membrane protein at atomic resolution by X-ray crystallography or nuclear magnetic resonance spectroscopy. They are challenging subjects for study owing to the difficulties associated with extraction and crystallization. In addition, structures of many water-soluble protein domains of IMPs are available in the Protein Data Bank. Their membrane-anchoring α-helices have been removed to facilitate the extraction and crystallization. Search integral membrane proteins in the PDB (based on gene ontology classification) IMPs can be divided into two groups: The most common type of IMP is the transmembrane protein (TM), which spans the entire biological membrane. Single-pass membrane proteins cross the membrane only once, while