Skin (Marvel Comics) had a greyish tone and, because of the extra amount, gave him the appearance of a melted candle. At one point, along with compressing his skin tighter against his body, Skin was learning to manipulate the pigment melanin in his epidermis in order to appear normal. However, performing these two stunts together caused him to have migraines and he soon gave up on the idea of being normal. In the alternate timeline of the Age of Apocalypse, Skin was featured in "Generation Next" as one of the protégés tapped by Colossus and Shadowcat to rescue Illyana Rasputin from enslavement at
Retinal pigment epithelium degeneration and retinitis pigmentosa. RPE are also involved in diabetic retinopathy. Gardner syndrome is characterized by FAP (Familial Adenomatous Polyps), osseous and soft tissue tumors, retinal pigment epithelium hypertrophy and impacted teeth. Retinal pigment epithelium The pigmented layer of retina or retinal pigment epithelium (RPE) is the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells. The RPE was known in the 18th and 19th centuries as the pigmentum nigrum, referring to the observation that the RPE is dark (black in many animals,