Aspirin to salicylic acid, the active component of willow extract. In 1853, chemist Charles Frédéric Gerhardt treated sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time; in the second half of the nineteenth century, other academic chemists established the compound's chemical structure and devised more efficient methods of synthesis. In 1897, scientists at the drug and dye firm Bayer began investigating acetylsalicylic acid as a less-irritating replacement for standard common salicylate medicines, and identified a new way to synthesize it. By 1899, Bayer had dubbed this drug Aspirin and was selling it around the world. The word
Acid rock Acid rock Acid rock is a loosely defined type of rock music that evolved out of the mid-1960s garage punk movement and helped launch the psychedelic subculture. The style is generally defined by heavy, distorted guitars, lyrics with drug references, and long improvised jams. Its distinctions from other genres can be tenuous, as much of the style overlaps with '60s punk, proto-metal, and early heavy, blues-based hard rock. The term, which derives its name from lysergic acid diethylamide (LSD), is sometimes used interchangeably with "psychedelic rock", but may refer more specifically to a more musically intense subgenre or sibling to