Androgen receptor the development and maintenance of the male sexual phenotype. In some cell types, testosterone interacts directly with androgen receptors, whereas, in others, testosterone is converted by 5-alpha-reductase to dihydrotestosterone, an even more potent agonist for androgen receptor activation. Testosterone appears to be the primary androgen receptor-activating hormone in the Wolffian duct, whereas dihydrotestosterone is the main androgenic hormone in the urogenital sinus, urogenital tubercle, and hair follicles. Hence, testosterone is responsible primarily for the development of male primary sexual characteristics, whereas dihydrotestosterone is responsible for secondary male characteristics. Androgens cause slow epiphysis, or maturation of the bones, but more of
Male lactation where male lactation occurs and it is not well understood what evolutionary factors control the development of this trait. The phenomenon of male lactation occurs in some species, notably the Dayak fruit bat ("Dyacopterus spadiceus"), and the lactating males may assist in the nursing of their infants. In addition, male goats are known to lactate on occasion. Human male breastfeeding is possible, but production of the hormone prolactin is necessary to induce lactation, so male lactation does not occur under normal conditions. Domperidone is a drug that can be used to increase lactation. Male lactation has also been seen during