Heart valve tricuspid valve has anterior, posterior, and septal cusps; and the mitral valve has just anterior and posterior cusps. The valves of the human heart can be grouped in two sets: 1- Two Atrioventricular (AV) valves to prevent backflow of blood from the ventricles into the atria a) Tricuspid valve, located between the right atrium and right ventricle. b) Bicuspid or mitral valve, located between the left atrium and left ventricle. 2- Two Semilunar valves to prevent the backflow of blood into the ventricle a) Pulmonary semilunar valve, located at the opening between the right ventricle and the pulmonary trunk. b)
Hypoplastic right heart syndrome Expression of these genes expression is regulated by various processes, including transcription and growth factors, as well as proteins like fibrillin, Wnt, BMP2, BMP 4, BMP5, BMP7, which aid in different heart development features like the valves and septum, and other substances, such as retinoid and folic acid.[5] Crucial steps in heart formation are development of the ventricles and atrium formation, as well as septation and valve formation. Any disturbances of such processes may lead to various congenital heart diseases and defects that could be initiated by various genetic, epigenetic or environmental factors. The most common heart malformations from genetic