Parasympathetic nervous system act in a complementary way increasing or slowing the heart rate. In this context, the vagus nerve acts on sinoatrial node slowing its conduction thus actively modulating vagal tone accordingly. This modulation is mediated by the neurotransmitter acetylcholine and downstream changes to ionic currents and calcium of heart cells. The vagus nerve plays a crucial role in heart rate regulation by modulating the response of sinoatrial node, vagal tone can be quantified by investigating heart rate modulation induced by vagal tone changes. As a general consideration, increased vagal tone (and thus vagal action) is associated with a diminished and more
Node (circuits) Node (circuits) In electrical engineering, a node is any point on a circuit where the terminals of two or more circuit elements meet. In circuit diagrams, connections are ideal wires with zero resistance, so a node may consist of the entire section of wire between elements, not just a single point. According to Ohm's law, "V = IR", the voltage across any two points of a node with negligible resistance is showing that the voltage at every point of a node is the same. However, there are some notable exceptions where the voltage difference is large enough to become significant: