Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian Sidamon-Eristavi 1930s, he mostly retired to teaching arts. Valerian Sidamon-Eristavi Valerian Sidamon-Eristavi (; 2 July 1889 – 9 June 1943) was a Georgian Modernist artist and set designer. Born in the town of Kvareli into a noble family, Valerian Sidamon-Eristavi studied arts at Tiflis and Moscow. Returning to Georgia in 1915, he made a name as a caricaturist and illustrator and later switched to historical painting. He became best known for his set design for the Georgian theatre and cinema, for which he fruitfully collaborated with the leading director Kote Marjanishvili. He worked as an art director for about 35 films