Glycogen storage disease type III enzymes to further convert these branched glycogen polymers to glucose, limit dextrinosis abnormally accumulates in the cytoplasm. Glycogen is a molecule the body uses to store carbohydrate energy. Symptoms of GSD-III are caused by a deficiency of the enzyme amylo-1,6 glucosidase, or debrancher enzyme. This causes excess amounts of an abnormal glycogen to be deposited in the liver, muscles and, in some cases, the heart. Glycogen storage disease type III presents during infancy with hypoglycemia and failure to thrive. Clinical examination usually reveals hepatomegaly. Muscular disease, including hypotonia and cardiomyopathy, usually occurs later. The liver pathology typically regresses as the
Campbell's Stores 1858-59, Sands Directory lists the following at Campbell's Wharf: Campbell & Co; Sugar Company's stores; JC Dibbs & Co, commission agents and wharfingers; Robert Nash, storekeeper; WH Eldred, Capt, Chili Flour Co; Chilian Consulate - Consul, WH Eldred. In 1861, it shows: Campbell & Co; Colonial Sugar Refining Co, stores; Peruvian guano stores; George Lloyd & Co stores; Robey & Co's stores; George Lewis custom house officer; and WH Eldred, broker & general agent. In 1863, it shows: 4. Merry Willis and Co, merchants; 3. Henry Fisher & Son, sugar factors; 2. Brown & Co, merchants; 1. EM Sayers &