Artificial cell for disease transmission, artificial red blood cells are desired because they eliminate drawbacks associated with allogenic blood transfusions such as blood typing, immune reactions and its short storage life of 42 days. A hemoglobin substitute may be stored at room temperature and not under refrigeration for more than a year. Attempts have been made to develop a complete working red blood cell which comprises carbonic not only an oxygen carrier but also the enzymes associated with the cell. The first attempt was made in 1957 by replacing the red blood cell membrane by an ultrathin polymeric membrane which was followed
Blood red dark red state, but quickly oxygenates upon exposure to air, turning a brighter shade of red. This happens more quickly with smaller volumes of blood such as a pinprick and less quickly from cuts or punctures that cause greater blood flows such as a puncture in the basilic vein: all blood collected during a phlebotomy procedure is deoxygenated blood, and it does not usually have a chance to become oxygenated upon leaving the body. Arterial blood, which is already oxygenated, is also already a brighter shade of red— this is the blood see from a pulsating neck, arm, or leg