Spectral sensitivity Spectral sensitivity Spectral sensitivity is the relative efficiency of detection, of light or other signal, as a function of the frequency or wavelength of the signal. In visual neuroscience, spectral sensitivity is used to describe the different characteristics of the photopigments in the rod cells and cone cells in the retina of the eye. It is known that the rod cells are more suited to scotopic vision and cone cells to photopic vision, and that they differ in their sensitivity to different wavelengths of light. It has been established that the maximum spectral sensitivity of the human eye under daylight
Retina of the retina. Recombinant adeno-associated virus (rAAV) vectors possess a number of features that render them ideally suited for retinal gene therapy, including a lack of pathogenicity, minimal immunogenicity, and the ability to transduce postmitotic cells in a stable and efficient manner. rAAV vectors are increasingly utilized for their ability to mediate efficient transduction of retinal pigment epithelium (RPE), photoreceptor cells and retinal ganglion cells. Each cell type can be specifically targeted by choosing the appropriate combination of AAV serotype, promoter, and intraocular injection site. Several clinical trials have already reported positive results using rAAV to treat Leber's congenital amaurosis,