Muscarinic antagonist brain, involving both increased levels of acetylcholine and degeneration of dopaminergic pathways (nigrostriatal pathway). Thus, in parkinsonism there is decreased level of dopaminergic activity. One method of balancing the neurotransmitters is through blocking central cholinergic activity using muscarinic receptor antagonists. Atropine acts on the M2 receptors of the heart and antagonizes the activity of acetylcholine. It causes tachycardia by blocking vagal effects on the sinoatrial node. Acetylcholine hyperpolarizes the sinoatrial node, which is overcome by MRA and thus increases the heart rate. If atropine is given by intramuscular or subcutaneous injection, it causes initial bradycardia. This is because by i.m/s.c
Node B Node B Node B is the telecommunications node in particular mobile communication networks, namely those that adhere to the UMTS standard. The Node B provides the connection between mobile phones (UEs) and the wider telephone network. UMTS is the dominating 3G standard. Node B corresponds to BTS (base transceiver station) in GSM. This is the hardware that is connected to the mobile phone network that communicates directly with mobile handsets. In contrast with GSM base stations, Node B uses WCDMA/TD-SCDMA as the air interface technology. As in all cellular systems, such as UMTS and GSM, the Node B contains radio