Vascular resistance recent results showing the sheath flow surrounding the plug flow in a vessel, the sheath flow size is not neglectible in the real blood flow velocity profile in a vessel. The velocity profile is directly linked to flow resistance in a vessel. The viscosity variations, according to Thurston, are also balanced by the sheath flow size around the plug flow. The secondary regulators of vascular resistance, after vessel radius, is the sheath flow size and its viscosity. Thurston, as well, shows that the resistance R is constant, where, for a defined vessel radius, the value η(δ)/δ is constant in the
Flow focusing seeded in hydrodynamic focussing which has been in existence since 1963, as was developed by flow cytometry scientist. The basic principle consists of a continuous phase fluid (focusing or sheath fluid) flanking or surrounding the dispersed phase (focused or core fluid), so as to give rise to droplet or bubble break-off in the vicinity of an orifice through which both fluids are extruded. The principle may be extended to two or more coaxial fluids; gases and liquids may be combined; and, depending of the geometry of the feed tube and orifices, the flow pattern may be cylindrical or planar. Both