Glipizide 10 milligrams. Glipizide sensitizes the beta cells of pancreatic islets of Langerhans insulin response, meaning that more insulin is released in response to glucose than would be without glipizide ingestion. Glipizide acts by partially blocking potassium channels among beta cells of pancreatic islets of Langerhans. By blocking potassium channels, the cell depolarizes, which results in the opening of voltage-gated calcium channels. The resulting calcium influx encourages insulin release from beta cells. Glipizide Glipizide is an oral rapid- and short-acting anti-diabetic medication from the sulfonylurea class. It is classified as a second-generation sulfonylurea, which means that it undergoes enterohepatic circulation. Second-generation
Ryan Langerhans Ryan Langerhans Ryan David Langerhans (born February 20, 1980) is an American former professional baseball outfielder. Langerhans was drafted in the third round of the 1998 Major League Baseball draft by the Atlanta Braves, and made his debut with them in 2002. He has also played in Major League Baseball for the Oakland Athletics, Washington Nationals, Seattle Mariners, Los Angeles Angels of Anaheim, and Toronto Blue Jays. Langerhans attended Round Rock High School in Round Rock, Texas. During the 1996 season, Langerhans batted .442 and was selected to the All-State team. His next season, 1997, Langerhans batted .427 and was