Atmosphere of Earth International Space Station orbits in this layer, between . The mesosphere is the third highest layer of Earth's atmosphere, occupying the region above the stratosphere and below the thermosphere. It extends from the stratopause at an altitude of about to the mesopause at above sea level. Temperatures drop with increasing altitude to the mesopause that marks the top of this middle layer of the atmosphere. It is the coldest place on Earth and has an average temperature around . Just below the mesopause, the air is so cold that even the very scarce water vapor at this altitude can be
Ozone layer This type of UV radiation is significantly less harmful to DNA, although it may still potentially cause physical damage, premature aging of the skin, indirect genetic damage, and skin cancer. The thickness of the ozone layer varies worldwide and is generally thinner near the equator and thicker near the poles. Thickness refers to how much ozone is in a column over a given area and varies from season to season. The reasons for these variations are due to atmospheric circulation patterns and solar intensity. The majority of ozone is produced over the tropics and is transported towards the poles by