Nonsteroidal anti-inflammatory drug more effective than salicin and, in addition to its fever-reducing properties, is anti-inflammatory and analgesic. In 1869, Hermann Kolbe synthesised salicylate, although it was too acidic for the gastric mucosa. The reaction used to synthesise aromatic acid from a phenol in the presence of CO2 is known as the Kolbe-Schmitt reaction. By 1897 the German chemist Felix Hoffmann and the Bayer company prompted a new age of pharmacology by converting salicylic acid into acetylsalicylic acid—named aspirin by Heinrich Dreser. Other NSAIDs were developed from the 1950s forward. In 2001, NSAIDs accounted for 70,000,000 prescriptions and 30 billion over-the-counter doses sold
Acid rock Acid rock Acid rock is a loosely defined type of rock music that evolved out of the mid-1960s garage punk movement and helped launch the psychedelic subculture. The style is generally defined by heavy, distorted guitars, lyrics with drug references, and long improvised jams. Its distinctions from other genres can be tenuous, as much of the style overlaps with '60s punk, proto-metal, and early heavy, blues-based hard rock. The term, which derives its name from lysergic acid diethylamide (LSD), is sometimes used interchangeably with "psychedelic rock", but may refer more specifically to a more musically intense subgenre or sibling to