Red blood cell synthesised by the kidney. Just before and after leaving the bone marrow, the developing cells are known as reticulocytes; these constitute about 1% of circulating red blood cells. The functional lifetime of a red blood cell is about 100–120 days, during which time the red blood cells are continually moved by the blood flow push (in arteries), pull (in veins) and a combination of the two as they squeeze through microvessels such as capillaries. They are also recycled in the bone marrow. The aging red blood cell undergoes changes in its plasma membrane, making it susceptible to selective recognition by
Urinary bladder mediate bladder diseases such as overactive bladder. The bladder is supplied by the vesical arteries and drained by the vesical veins. The superior vesical artery supplies blood to the upper part of the bladder. The lower part of the bladder is supplied by the inferior vesical artery in males and by the vaginal artery in females, both of which are branches of the internal iliac arteries. In females, the uterine arteries provides additional blood supply. Venous drainage begins in a network of small vessels on the lateral and posterior surfaces of the bladder, which coalesce and pass backwards along the