Color blindness as part of the retinal damage caused by diabetes. Vitamin A deficiency may also cause color blindness. Some subtle forms of color blindness may be associated with chronic solvent-induced encephalopathy (CSE), caused by long-time exposure to solvent vapors. Red–green color blindness can be caused by ethambutol, a drug used in the treatment of tuberculosis. The typical human retina contains two kinds of light cells: the rod cells (active in low light) and the cone cells (active in normal daylight). Normally, there are three kinds of cone cells, each containing a different pigment, which are activated when the pigments absorb light.
Von Kries coefficient law von Kries coefficient law built upon theories and research done by Hermann von Helmholtz. A German physicist and physician, Helmholtz asserted that “the nervous substance in question is less sensitive to reacting light falling on it than the rest of the retina that was not previously stimulated”. Helmholtz, along with Thomas Young, proposed the trichromatic theory, or the Young–Helmholtz theory, that stated that the retina contains three types of cones, which respond to light of three different wavelengths, corresponding to red, green, or blue. Activation of these cones in different combinations and to different degrees results in the perception of