History of diabetes further clarified in 1921, when Sir Frederick Grant Banting and Charles Herbert Best repeated the work of Von Mering and Minkowski, and went further to demonstrate they could reverse induced diabetes in dogs by giving them an extract from the pancreatic islets of Langerhans of healthy dogs. The islets of Langerhans was discovered in 1869 by an anatomist named Paul Langerhans. He identified the keys cells in the pancreas which produce the main substance that controls glucose levels in the body. Banting, Best, and colleagues (especially the chemist Collip) went on to purify the hormone insulin from bovine pancreases at
Ryan Langerhans going a combined 0-for-4 with a walk and an error. On May 2, 2007, he was traded to the Washington Nationals for Chris Snelling. On June 28, he was traded to the Seattle Mariners for utility player Mike Morse. With the Mariners, Langerhans had better results hitting curve balls and sliders than fastballs and changeups, causing some speculation that this skill set could be responsible for his tendency to play in a part-time role. He was non-tendered at the deadline to offer arbitration on December 12, 2009. On December 18, however, the Mariners re-signed Langerhans to a minor league contract.