Sinoatrial node rate, and increasing heart rate. An increase in heart rate is known as positive chronotropy. The parasympathetic nerves supplying the SA node (in particular the Vagus nerves) originate in the brain. These nerves release a neurotransmitter called acetylcholine (ACh). ACh binds to a receptor called an M2 muscarinic receptor, located on the SA node membrane. Activation of this M2 receptor, then activates a protein called a G-protein (in particular G protein, i for inhibitory). Activation of this G-protein, blocks the cAMP pathway, reducing its effects, therefore inhibiting sympathetic activity and slowing action potential production. As well as this, the G-protein
Orbital node terms αναβιβάζων and καταβιβάζων were also used for the ascending and descending nodes, giving rise to the English words "anabibazon" and "catabibazon". For the orbit of the Moon around Earth, the plane is taken to be the ecliptic, not the equatorial plane. The gravitational pull of the Sun upon the Moon causes its nodes to gradually precess westward, completing a cycle in approximately 18.6 years. Orbital node An orbital node is either of the two points where an orbit intersects a plane of reference to which it is inclined. A non-inclined orbit, which is contained in the reference plane, has