Hemoglobin failure, or abnormal hemoglobin (such as that of sickle-cell disease). The ability of each hemoglobin molecule to carry oxygen is normally modified by altered blood pH or CO, causing an altered oxygen–hemoglobin dissociation curve. However, it can also be pathologically altered in, e.g., carbon monoxide poisoning. Decrease of hemoglobin, with or without an absolute decrease of red blood cells, leads to symptoms of anemia. Anemia has many different causes, although iron deficiency and its resultant iron deficiency anemia are the most common causes in the Western world. As absence of iron decreases heme synthesis, red blood cells in iron deficiency
Blood–gas partition coefficient (lipid) tissues of the brain where it can exert its effect. The potency of an anesthetic is associated with its lipid solubility which is measured by its oil/gas partition coefficient. Minimum Alveolar Concentration (MAC) is defined as the alveolar concentration of anesthetic gas that prevents a movement response in half of subjects undergoing a painful (surgical) stimulus; simplified, it is the exhaled gas concentration required to produce anaesthetic effects - an inverse indicator of anesthetic gas potency. Partition coefficients at 37 °C. Blood–gas partition coefficient Blood–gas partition coefficient, also known as Ostwald coefficient for blood–gas, is a term used in