Stimulus modality lit area, the eyes require time for a good quantity of rhodopsin to regenerate. As more time passes, there is a higher chance that the photons will split an unbleached photopigment because the rate of regeneration will have surpassed the rate of bleaching. This is called adaptation. Humans are able to see an array of colours because light in the visible spectrum is made up of different wavelengths (from 380 to 760 nm). Our ability to see in colour is due to three different cone cells in the retina, containing three different photopigments. The three cones are each specialized to
Intrinsically photosensitive retinal ganglion cells able to isomerize "all-trans-"retinal into "11-cis-"retinal when stimulated with light without help from additional cells. The two isoforms of melanopsin differ in their spectral sensitivity, for the "11-cis"-retinal isoform is more responsive to shorter wavelengths of light, while the "all-trans" isoform is more responsive to longer wavelengths of light. ipRGCs are both pre- and postsynaptic to dopaminergic amacrine cells (DA cells) via reciprocal synapses, with ipRGCs sending excitatory signals to the DA cells and the DA cells sending inhibitory signals to the ipRGCs. These inhibitory signals are mediated through GABA which is co-released from the DA cells along with dopamine.