Nav1.5 kb. The gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5’ untranslated region (5’UTR) and exon 28 the 3’ untranslated region (3’UTR) of the RNA. SCN5A is part of a family of 10 genes that encode different types of sodium channels, i.e. brain-type (Na1.1, Na1.2, Na1.3, Na1.6), neuronal channels (Na1.7, Na1.8 and Na1.9), skeletal muscle channels (Na1.4) and the cardiac sodium channel Na1.5. SCN5A is mainly expressed in the heart, where expression is abundant in working myocardium and conduction tissue. In contrast, expression is low in the sinoatrial node and atrioventricular node.
Node graph architecture Node graph architecture Node graph architecture is a type of software design which builds around modular node components which can be connected to form a graph. Often the software's underlying node graph architecture is also exposed to the end user as a two-dimensional visualization of the node graph. The node graph architecture is popular in the film and computer games industry. There are often many different node types participating in the node graph. For example, in the Nuke Manual they list hundreds of nodes. Each node type performs one specific task. For example, Nuke's Merge node produces an output image