Marine life appeared in the form of fish, which live exclusively in water. Some of these evolved into amphibians which spend portions of their lives in water and portions on land. Other fish evolved into land mammals and subsequently returned to the ocean as seals, dolphins or whales. Plant forms such as kelp and algae grow in the water and are the basis for some underwater ecosystems. Plankton, and particularly phytoplankton, are key primary producers forming the general foundation of the ocean food chain. Marine invertebrates exhibit a wide range of modifications to survive in poorly oxygenated waters including breathing tubes (see
Microscopic colitis of 7.1 per 100,000 person-years and 12.6 per 100,000 person-years for collagenous colitis for lymphocytic colitis, respectively. Prevalence has been estimated as 103 cases per 100,000 persons. People who develop microscopic colitis are characteristically, though not exclusively, middle-aged females. The average age of diagnosis is 65 but 25% of cases are diagnosed below the age of 45. The condition of microscopic colitis was first described as such in 1982. Lymphocytic colitis was described in 1989. Collagenous colitis was recognised earlier, in 1976. Microscopic colitis Microscopic colitis refers to two related medical conditions which cause diarrhea: collagenous colitis and lymphocytic colitis.