Light skin of UVA can penetrate deeply into the dermis in persons with light skin pigmentation with little protective melanin pigment. The characteristic of fair skin, red hair, and freckling is associated with high amount of pheomelanin, little amounts of eumelanin. This phenotype is caused by a loss-of-function mutation in the melanocortin 1 receptor (MC1R) gene. However, variations in the MC1R gene sequence only have considerable influence on pigmentation in populations where red hair and extremely fair skin is prevalent. The gene variation’s primary effect is to promote eumelanin synthesis at the expense of pheomelanin synthesis, although this contributes to very little
The Painted Skin "a typical piece of moral didacticism that denounces sexual promiscuity, extols faithfulness, and endorses belief in karma and retribution." "The Painted Skin" utilises both the "zhiguai" and "chuanqi" styles of writing in bringing out "the ghost's critical and creative writing", whereas the complexity of prose parallels the "cultural ramifications of the ghost." Skin is a major plot device in "The Painted Skin", serving as a "path between the separate worlds of human and animal, or the natural and the supernatural". Reality versus perception of it is another overarching issue; what Wang deems to be a pretty female is in fact