Free fatty acid receptor 1 high abundance. FFA1 receptors are present over the entire brain, but in highest numbers in the medulla oblongata and the substantia nigra. Recent studies have also observed that FFA1 was present in the olfactory bulb, striatum, hippocampus, midbrain, hypothalamus, cerebellum, cerebral cortex and in the spinal cord. Fatty acids play an important role in normal brain development as well as maintaining proper neuronal function. It has been found that certain fatty acids that are in abundance in the brain may be linked with FFA1. These fatty acids likely activate FFA1, inducing an intracellular response. It has been found that docosahexaenoic
Anatomy of the cerebellum cerebellar cortex. Under resting conditions in animal experiments, groups of olivary neurons discharge synchronously at 5 to 10 Hz (impulses/s). In the cerebellar cortex, the response of Purkinje cells takes the form of complex spikes. The cerebellum send its projections back to the cerebral cortex via the Cerebellothalamic tract. The cerebellar lateral expansion, or the neocerebellum, may be associated with cognitive functions, and it is anatomically linked with the lateral prefrontal cortex. It shows greatest activity during speech, with a one-sided predominance consistent with a possible linkage (via the thalamus) with the motor speech area. When lesions occur in the