Muscarinic antagonist brain, involving both increased levels of acetylcholine and degeneration of dopaminergic pathways (nigrostriatal pathway). Thus, in parkinsonism there is decreased level of dopaminergic activity. One method of balancing the neurotransmitters is through blocking central cholinergic activity using muscarinic receptor antagonists. Atropine acts on the M2 receptors of the heart and antagonizes the activity of acetylcholine. It causes tachycardia by blocking vagal effects on the sinoatrial node. Acetylcholine hyperpolarizes the sinoatrial node, which is overcome by MRA and thus increases the heart rate. If atropine is given by intramuscular or subcutaneous injection, it causes initial bradycardia. This is because by i.m/s.c
Exposed node problem Exposed node problem In wireless networks, the exposed node problem occurs when a node is prevented from sending packets to other nodes because of a neighboring transmitter. Consider an example of 4 nodes labeled R1, S1, S2, and R2, where the two receivers (R1, R2) are out of range of each other, yet the two transmitters (S1, S2) in the middle are in range of each other. Here, if a transmission between S1 and R1 is taking place, node S2 is prevented from transmitting to R2 as it concludes after carrier sense that it will interfere with the transmission by