Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian (emperor) have forced Valerian to swallow molten gold (the other version of his death is almost the same but it says that Valerian was killed by being flayed alive) and then had Valerian skinned and his skin stuffed with straw and preserved as a trophy in the main Persian temple. It was further alleged that it was only after a later Persian defeat against Rome that his skin was given a cremation and burial. The captivity and death of Valerian has been frequently debated by historians without any definitive conclusion. According to the modern scholar Touraj Daryaee, contrary to the account