Transgender hormone therapy (male-to-female) medical professional. Inducers of CYP3A4 and other cytochrome P450 enzymes can reduce the effects of MTF HRT. A variety of different sex-hormonal medications are used in feminizing hormone therapy for transgender women. These include estrogens to induce feminization and suppress testosterone levels; antiandrogens such as androgen receptor antagonists, antigonadotropins, GnRH modulators, and 5α-reductase inhibitors to further oppose the effects of androgens like testosterone; and progestogens for various possible though uncertain benefits. Estrogens are the major sex hormones in women, and are responsible for the development and maintenance of feminine secondary sexual characteristics, such as breasts, wide hips, and a feminine
Sexual Preference (book) Sexual Preference (book) Sexual Preference: Its Development in Men and Women (1981) is a book about the development of sexual orientation by the psychologist Alan P. Bell and the sociologists Martin S. Weinberg and Sue Kiefer Hammersmith, in which the authors reevaluate what were at the time of its publication widely held ideas about the origins of heterosexuality and homosexuality, sometimes rejecting entirely the factors proposed as causes, and in other cases concluding that their importance had been exaggerated. Produced with the help of the American National Institute of Mental Health, the study was a publication of the Institute for