Origin of the domestic dog to the domestic dog and modern wolf lineages. The gray wolf is thought to be ancestral to the domestic dog, however its relationship to "C. variabilis", and the genetic contribution of "C. variabilis" to the dog, is the subject of debate. The Zhokhov Island (8,700 YBP) and Aachim (1,700 YBP) canid haplotypes fell within the domestic dog clade, cluster with S805, and also share their haplotypes with – or are one mutation away from – the Tibetan wolf ("C. l. chanco") and the recently-extinct Japanese wolf ("C. l. hodophilax"). This may indicate that these canids retained the genetic signature of
Origin of the domestic dog agriculture, which was approximately 10,000 years before present (YBP). The earlier association of dogs with humans may have allowed dogs to have a profound influence on the course of early human history and the development of civilization. However, the timing, geographic locations, and ecological conditions that led to dog domestication are not agreed. Genetic studies indicate that the gray wolf is the closest living relative of the dog, with no evidence of any other canine species having contributed. Attempting to reconstruct the dog's lineage through the phylogenetic analysis of DNA sequences from modern dogs and wolves has given conflicting results