Tendon the presence of denatured collagen are factors that are believed to cause weakening of the tendon ECM and an increase in the potential for another rupture to occur. In response to repeated mechanical loading or injury, cytokines may be released by tenocytes and can induce the release of MMPs, causing degradation of the ECM and leading to recurring injury and chronic tendinopathies. A variety of other molecules are involved in tendon repair and regeneration. There are five growth factors that have been shown to be significantly upregulated and active during tendon healing: insulin-like growth factor 1 (IGF-I), platelet-derived growth factor
Tendon, Vosges the Bonne Fontaine col at an altitude of 677 m. The "ban" of Tendon ("Tandon"), comprising the villages of Tendon, Houx, Laveline, Dehiex, Chamontaruz and La Poirie, belonged to the bailiwick of Remiremont under the Ancien Régime and depended on the mastery of the waters and forests Épinal. It followed the dress of Lorraine. In the church, the inhabitants of the current parish of Tendon were part of that of Docelles. This ended on 3 September 1707 when the bishow of Toul elevated the small Tendon chapel, which had been built 25 years earlier, into a parish. The bishop's decision