Development of the endocrine system of gestation, somatotroph cells begin to develop with cytoplasmic expression of human growth hormone. Once a fetus reaches 12 weeks of development, the thyrotrophs begin expression of Beta subunits for TSH, while gonadotrophs being to express beta-subunits for LH and FSH. Male fetuses predominately produced LH-expressing gonadotrophs, while female fetuses produce an equal expression of LH and FSH expressing gonadotrophs. At 24 weeks of gestation, prolactin-expressing lactotrophs begin to emerge. Development of the endocrine system The fetal endocrine system is one of the first systems to develop during prenatal development. The fetal adrenal cortex can be identified within four weeks
Endocrine bone disease Endocrine bone disease An endocrine bone disease is a bone disease associated with a disorder of the endocrine system. An example is osteitis fibrosa cystica. The thyroid, parathyroid, pituitary, or adrenal glands, and the pancreas are parts of the endocrine system, and, therefore are associated with the endocrine bone disease. Some common endocrine disorders are hypothyroidism, hyperthyroidism, Paget’s disease, Osteoporosis, and diabetes. The thyroid gland produces thyroxin (T3, and T4) which is necessary for normal development of the nervous system. Its functions include: promoting growth, increasing basal metabolic rate and controlling body temperature. Adequate iodine intake is necessary for the