Sickle cell disease other genetic diseases) among African Americans compared to West Africans. Another factor that limits the spread of sickle cell genes in North America is the relative absence of polygamy, which allows affected males to continue to produce many children with multiple partners. The loss of red blood cell elasticity is central to the pathophysiology of sickle cell disease. Normal red blood cells are quite elastic, which allows the cells to deform to pass through capillaries. In sickle cell disease, low oxygen tension promotes red blood cell sickling and repeated episodes of sickling damage the cell membrane and decrease the cell's
The Blood Cell The Blood Cell The Blood Cell is a BBC Books original novel written by James Goss and based on the long-running British science fiction television series "Doctor Who". It features the Twelfth Doctor and Clara Oswald. The book was released on 11 September 2014 along with "Silhouette" and "The Crawling Terror". "The Blood Cell" gained generally positive reviews, calling it an "effective chiller". Most of them commented the unusual way of narration from the first-person perspective of the administrator of the prison in which the book is set known as the Governor. More grim and darker tone is also noted.