Pharmacodynamics of progesterone women, this effect being the result of suppression of the mid-cycle surge in gonadotropin secretion, is 300 mg/day. However, this figure is based on limited clinical data. Conversely, treatment with a high dosage of oral progesterone of 100 mg four times per day (or 400 mg/day total) in men for 10 days that resulted in approximately mid-luteal phase levels of progesterone (7.9–9.4 ng/mL; measured by ) did not cause any change in testosterone levels, suggesting that progesterone has little or no antigonadotropic effect in males at typical clinical dosages. In addition, a study found that administration of 1,000 mg/day oral
Menstrual synchrony Israel. Twenty seven families, which had from two to seven sisters 13 years or older and collected data on menstrual cycle onsets over a three-month period. Using the methods of, they reported menstrual synchrony occurred for the first two months, but not for the third month for roommate sisters, close friend roommates, and for families as a whole. Strassmann investigated whether menstrual synchrony occurred in a natural fertility population of Dogon village women. Her study consisted of 122 Dogon women with an average lifetime fertility rate of 8.6 ± .3 live births per woman. Their median cycle length was 30