Antibiotic synergy with enterococcal endocarditis experienced a high relapse rate when penicillin G alone was used for treatment and a demonstrably lower relapse rate when streptomycin was combined with penicillin G to combat the infection. Since that time the research community has conducted numerous studies regarding the effects and possibilities of antibiotic combinations. Today, combination therapy is recognized as providing a broad spectrum of antibiotic coverage, effectively fighting polymicrobial infections, minimizing selection for antibiotic resistant strains, lowering dose toxicity where applicable, and in some cases providing synergistic activity. Antibiotic synergy is desirable in a clinic sense for several reasons. At the patient
Antibiotic Action drug development, and Antimicrobial stewardship. Antibiotic Action Antibiotic Action is a UK-based initiative that works to raise global awareness about antibiotic resistance, and is funded by the British Society for Antimicrobial Chemotherapy (BSAC), a UK registered charity. Antibiotic Action seeks to inform and educate people from various backgrounds, ranging from politicians to healthcare professionals to the public, about the need for discovery, research, and development of new treatments for bacterial infections to combat antibiotic resistance. It also aims to strengthen and enhance academic-industrial partnerships by bringing together communities that need antibiotics with academia, health-care professionals, and pharmaceutical companies to address