Sickle cell nephropathy Sickle cell nephropathy Sickle cell nephropathy is a type of nephropathy associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla, coupled with the slow blood flow in the vasa recta, favors sickling of red blood cells, with resultant local infarction (papillary necrosis). Functional tubule defects in patients with sickle cell disease are likely the result of partial ischemic injury to the renal tubules. Also the sickle cell disease in young patients is characterized by renal hyperperfusion,
White blood cell underlying cause, though the cause may not always be found. The complete blood cell count is a blood panel that includes the overall WBC count and various subsets such as the absolute neutrophil count. Reference ranges for blood tests specify the typical counts in healthy people. TLC- (Total leucocyte count): Normal TLC in an adult person is 6000-8000WBC/mm^3 of blood. DLC- (Differential leucocyte count): Number/ (%) of different type of leucocyte in per cubic mm. of blood. White blood cell White blood cells (also called leukocytes or leucocytes and abbreviated as WBCs) are the cells of the immune system that