KRT31 Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping KRT31 Keratin, type I cuticular Ha1 is a protein that in humans is encoded by the "KRT31" gene. The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. Model organisms have been
Nestin (protein) of actively growing pluripotent adult stem cells. Green fluorescent protein (GFP), whose expression is driven by the nestin regulatory element in transgenic mice, serves to mark hair follicle stem cells. These cells can differentiate into neurons, glia, keratinocytes, smooth muscle cells and melanocytes in vitro. Thus, hair follicle stem cells provide an effective, accessible, autologous source of stem cells for treatment of peripheral nerve injury. Nestin has recently received attention as a marker for detecting newly formed endothelial cells. Nestin is an angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue. Nestin (protein) has been shown to interact with