Aspirin to salicylic acid, the active component of willow extract. In 1853, chemist Charles Frédéric Gerhardt treated sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time; in the second half of the nineteenth century, other academic chemists established the compound's chemical structure and devised more efficient methods of synthesis. In 1897, scientists at the drug and dye firm Bayer began investigating acetylsalicylic acid as a less-irritating replacement for standard common salicylate medicines, and identified a new way to synthesize it. By 1899, Bayer had dubbed this drug Aspirin and was selling it around the world. The word
Should Have Known Better shroud into a tender lyric about shoving aside his fear, discovering an oasis of perspective when he looks to his brother’s newborn daughter and sees his mother in her face. When he sings 'nothing can be changed,' he doesn’t sound resigned, but ready to look forward. It’s the dawn at the end of a long night, a prayer that past traumas might be healed by a beautiful present." Should Have Known Better "Should Have Known Better" is a song by American singer-songwriter and multi-instrumentalist Sufjan Stevens. It is the second track and second single from his seventh studio album, "Carrie