Red blood cell Much of this potential appears to be contributed by the exposed sialic acid residues in the membrane: their removal results in zeta potential of −6.06 mV. When red blood cells undergo shear stress in constricted vessels, they release ATP, which causes the vessel walls to relax and dilate so as to promote normal blood flow. When their hemoglobin molecules are deoxygenated, red blood cells release S-nitrosothiols, which also act to dilate blood vessels, thus directing more blood to areas of the body depleted of oxygen. Red blood cells can also synthesize nitric oxide enzymatically, using L-arginine as substrate, as do
Blood cell are based on the inappropriate production of white blood cells. Platelets, or "thrombocytes", are very small, irregularly shaped clear cell fragments, 2–3 µm in diameter, which derive from fragmentation of megakaryocytes. The average lifespan of a platelet is normally just 5 to 9 days. Platelets are a natural source of growth factors. They circulate in the blood of mammals and are involved in hemostasis, leading to the formation of blood clots. Platelets release thread-like fibers to form these clots. If the number of platelets is too low, excessive bleeding can occur. However, if the number of platelets is too high,