Nav1.5 kb. The gene consists of 28 exons, of which exon 1 and in part exon 2 form the 5’ untranslated region (5’UTR) and exon 28 the 3’ untranslated region (3’UTR) of the RNA. SCN5A is part of a family of 10 genes that encode different types of sodium channels, i.e. brain-type (Na1.1, Na1.2, Na1.3, Na1.6), neuronal channels (Na1.7, Na1.8 and Na1.9), skeletal muscle channels (Na1.4) and the cardiac sodium channel Na1.5. SCN5A is mainly expressed in the heart, where expression is abundant in working myocardium and conduction tissue. In contrast, expression is low in the sinoatrial node and atrioventricular node.
Node deletion Node deletion Node deletion is the procedure of removing a node from a network, where the node is either chosen randomly or directly. Node deletion is used to test the robustness and the attack tolerance of networks. Understanding how a network changes in response to node deletion is critical in many empirical networks. Application varies across many fields, including the breakdown of the World Wide Web via router removal, elimination of epidemics or fighting against criminal organizations. Removing a node or multiple nodes randomly from a network means that the elimination of a set of nodes happens with a certain