Leiden University at the university. The learning and reputation of Jacobus Gronovius, Herman Boerhaave, Tiberius Hemsterhuis and David Ruhnken, among others, enabled Leiden to maintain its reputation for excellence down to the end of the 18th century. At the end of the nineteenth century, Leiden University again became one of Europe's leading universities. At the world’s first university low-temperature laboratory, professor Heike Kamerlingh Onnes achieved temperatures of only one degree above absolute zero of −273 degrees Celsius. In 1908 he was also the first to succeed in liquifying helium and can be credited with the discovery of the superconductivity in metals. The
Big Science expertise only partially overlaps. Galison introduced the notion of "trading zones," borrowed from the sociolinguistic study of pidgins, to characterize how such groups learn to interact. Other historians have postulated many "precursors" to Big Science in earlier times: the Uraniborg of Tycho Brahe (in which massive astronomical instruments were made, often with little practical purpose) and the large cryogenics laboratory established by Heike Kamerlingh Onnes in 1904 have been cited as early examples of Big Science. Big Science Big science is a term used by scientists and historians of science to describe a series of changes in science which occurred