History of genetics code for specific proteins, leading to the "one gene, one enzyme" hypothesis. Oswald Avery, Colin Munro MacLeod, and Maclyn McCarty showed in 1944 that DNA holds the gene's information. In 1952, Rosalind Franklin and Raymond Gosling produced a strikingly clear x-ray diffraction pattern indicating a helical form, and in 1953, James D. Watson and Francis Crick demonstrated the molecular structure of DNA. Together, these discoveries established the central dogma of molecular biology, which states that proteins are translated from RNA which is transcribed by DNA. This dogma has since been shown to have exceptions, such as reverse transcription in retroviruses.
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid autobiographical account of the discovery of the double-helical, molecular structure of DNA called "The Double Helix", which was not publicly accepted either by Crick or Wilkins. Furthermore, Erwin Chargaff also printed a rather "unsympathetic review" of Watson's book in the March 29, 1968 issue of "Science". In the book, Watson stated among other things that he and Crick had access to some of Franklin's data from a source that she was not aware of, and also that he had seen—without her permission—the B-DNA X-ray diffraction pattern obtained by Franklin and Gosling in May 1952 at King's in London. In particular,