Red blood cell Much of this potential appears to be contributed by the exposed sialic acid residues in the membrane: their removal results in zeta potential of −6.06 mV. When red blood cells undergo shear stress in constricted vessels, they release ATP, which causes the vessel walls to relax and dilate so as to promote normal blood flow. When their hemoglobin molecules are deoxygenated, red blood cells release S-nitrosothiols, which also act to dilate blood vessels, thus directing more blood to areas of the body depleted of oxygen. Red blood cells can also synthesize nitric oxide enzymatically, using L-arginine as substrate, as do
Neonatal red cell transfusion baby (e.g. wristband). Paedipacks are multiple aliquots made from one adult blood donation. By using paedipacks, the baby is exposed to blood from fewer blood donors. ABO blood grouping and screening for antibodies in neonates differs from blood grouping in adults and older children. Any antibodies detected are the mother's antibodies rather than the baby's. Therefore, any donor blood given to the baby must be ABO and D compatible with both mother and baby; and antigen-negative for any clinically significant maternal antibodies. Necrotising enterocolitis may occur after a red cell transfusion in neonates, although there is an association between the