Valerian (herb) particular binding site. Hydrophilic extractions of the herb commonly sold over the counter, however, probably do not contain significant amounts of isovaltrate. Valerenic acid in valerian stimulates serotonin receptors as a partial agonist, including 5-HT which is implicated in the sleep-wake cycle. The chief constituent of valerian is a yellowish-green to brownish-yellow oil present in the dried root, varying in content from 0.5 to 2.0%. This variation in quantity may be determined by location; a dry, stony soil yields a root richer in oil than moist, fertile soil. The volatile oils that form the active ingredient are pungent, somewhat reminiscent
Valerian (emperor) have forced Valerian to swallow molten gold (the other version of his death is almost the same but it says that Valerian was killed by being flayed alive) and then had Valerian skinned and his skin stuffed with straw and preserved as a trophy in the main Persian temple. It was further alleged that it was only after a later Persian defeat against Rome that his skin was given a cremation and burial. The captivity and death of Valerian has been frequently debated by historians without any definitive conclusion. According to the modern scholar Touraj Daryaee, contrary to the account