Pancreatic juice Pancreatic juice Pancreatic juice is a liquid secreted by the pancreas, which contains a variety of enzymes, including trypsinogen, chymotrypsinogen, elastase, carboxypeptidase, pancreatic lipase, nucleases and amylase. The pancreas is located in the visceral region, and is a major part of the digestive system required for proper digestion and subsequent assimilation of macronutrient substances required for living. Pancreatic juice is alkaline in nature due to the high concentration of bicarbonate ions. Bicarbonate is useful in neutralizing the acidic gastric acid, allowing for effective enzymic changes. Pancreatic juice secretion is principally regulated by the hormones secretin and cholecystokinin, which are produced
Calponin 3, acidic Calponin 3, acidic Calponin 3. acidic is a protein that in humans is encoded by the "CNN3" gene. The "CNN3" gene is located at 1p22-p21 in the human chromosomal genome. "CNN3" gene contains 7 exons and encodes calponin 3, a 36.4-kDa protein consisting of 329 amino acids with isoelectric point (pI) of 5.84. Calponin 3 is known as acidic calponin. Among three isoforms of calponin, less is known for the gene regulation and function of calponin 3. Nonetheless, much has been learned from extensive studies on the homologous genes "CNN1" and "CNN2" that encode calponin 1 and calponin 2. "CNN3"