Rosalind Franklin and DNA Rosalind Franklin and DNA Rosalind Franklin and DNA is a biography of an English chemist Rosalind Franklin (1920–1958) written by her American friend Anne Sayre in 1975. Franklin was a physical chemist who made pivotal research in the discovery of the structure of DNA, known as "the most important discovery" in biology. DNA itself had become "life's most famous molecule". While working at the King's College London in 1951, she discovered two types of DNA called A-DNA and B-DNA. Her X-ray images of DNA indicated helical structure. Her X-ray image of B-DNA (called Photo 51) taken in 1952 became the
Fiber diffraction eliminates fiber tilt, unwarps the detector image, and corrects the scattering intensity. The correct equation for the determination of β has been presented by Norbert Stribeck. Fiber diffraction data led to several important advances in the development of structural biology, e.g., the original models of the α-helix and the Watson-Crick model of double-stranded DNA. The animation shows the geometry of fiber diffraction. It is based on the notions proposed by Polanyi. Reference direction is the primary beam (label: X-ray). If the fiber is tilted away from the perpendicular direction by an angle β, as well the information about its molecular