Effect of spaceflight on the human body of muscle fibre prominent in muscles also change. Slow twitch endurance fibres used to maintain posture are replaced by fast twitch rapidly contracting fibres that are insufficient for any heavy labour. Advances in research on exercise, hormone supplements and medication may help maintain muscle and body mass. Bone metabolism also changes. Normally, bone is laid down in the direction of mechanical stress. However, in a microgravity environment there is very little mechanical stress. This results in a loss of bone tissue approximately 1.5% per month especially from the lower vertebrae, hip and femur. Due to microgravity and the decreased load
What's Bred in the Bone and provides Cornish with plenty, most obviously at the hands of his childhood classmates and his artistic master in Germany, but also in two love affairs and in a friendship with a young man who in some ways is Cornish's apprentice. Another form of adversity is Cornish's situation as a talented artist whose interests and skills are out of fashion. First published by Macmillan of Canada in 1985, "What's Bred in the Bone" was on the short list for the 1986 Booker Prize. "What's Bred in the Bone" is the second novel of the "Cornish Trilogy". It was followed by