Transgender hormone therapy (male-to-female) medical professional. Inducers of CYP3A4 and other cytochrome P450 enzymes can reduce the effects of MTF HRT. A variety of different sex-hormonal medications are used in feminizing hormone therapy for transgender women. These include estrogens to induce feminization and suppress testosterone levels; antiandrogens such as androgen receptor antagonists, antigonadotropins, GnRH modulators, and 5α-reductase inhibitors to further oppose the effects of androgens like testosterone; and progestogens for various possible though uncertain benefits. Estrogens are the major sex hormones in women, and are responsible for the development and maintenance of feminine secondary sexual characteristics, such as breasts, wide hips, and a feminine
Asia Pacific Coalition on Male Sexual Health Asia Pacific Coalition on Male Sexual Health The Asia Pacific Coalition on Male Sexual Health, also known as APCOM, is a network of non-profit organizations which share the mission of improving male sexual health in South Asia, East Asia, and the Pacific Islands. APCOM was launched in July 2007 after delegates to the Delhi 2006 International Consultation on Male Sexual Health and HIV in Asia and the Pacific identified a need for more organization in the field of male sexual health. APCOM was founded as an autonomous, regional coalition of citizen groups, government representatives, funders, technical consultants and the United