John Jacob Abel the position of chair of the department until he retired at the age of 75 in 1932. Ever since his early years in Europe, Abel showed great interest in isolating pure form of internal gland hormones. The first work that led to his international reputation as a pharmacologist and biochemist was the isolation of epinephrine from adrenal medulla. However, he was only able to isolate a monobenzoyl derivative of epinephrine. While he was improving his processes on decomposing the benzoyl derivative to obtain salts of epinephrine using saponification, a Japanese chemist J. Takamine, who had visited his lab, was able
John Jacob Abel would have on managing the damaging effects of renal failure. The vividiffusion apparatus Abel devised is the precursor to the modern day dialysis machine. He summarized his work in a paper published in 1913, "On the Removal of Diffusable Substances from the Circulating Blood by Means of Dialysis" by Transfusion Science. Abel's work on insulin started with an invitation from his old friend Arthur A. Noyes at California Institute of Technology. Noyes had just received a grant from the Carnegie Corporation for research on insulin, and he thought that Abel would be the right person to lead that research. After