Broad-spectrum antibiotic focusing on evidence-based approaches to minimize resistance. In humans: In veterinary medicine, co-amoxiclav, (in small animals); penicillin & streptomycin and oxytetracycline (in farm animals); penicillin and potentiated sulfonamides (in horses). Broad-spectrum antibiotic The term broad-spectrum antibiotic can refer to an antibiotic that acts on the two major bacterial groups, gram-positive and gram-negative, or any antibiotic that acts against a wide range of disease-causing bacteria. These medications are used when a bacterial infection is suspected but the group of bacteria is unknown (also called empiric therapy) or when infection with multiple groups of bacteria is suspected. This is in contrast to
Antibiotic use in livestock common foods harboring these pathogens. There is evidence that a large proportion of resistant "E. coli" isolates causing blood stream infections in people are from livestock produced as food. When manure from antibiotic-fed swine is used as fertilizer elsewhere, the manure may be contaminated with bacteria which can infect humans. Studies have also shown that direct contact with livestock can lead to the spread of antibiotic-resistant bacteria from animals to humans. Sampling of retail meats such as turkey, chicken, pork and beef consistently show high levels of Enterobacteriaceae. Rates of resistant bacteria in these meats are high as well. Sources