I-motif DNA of 0.2 ppm. I-motif DNA i-motif DNA is a type of deoxyribonucleic acid, discovered in 2018, that is found in the nuclei of human cells. An abbreviation of intercalated motif, the four-strand i-motif is unlike the iconic double helix DNA. I-motifs are four-stranded quadruplex structures formed by cytosine-rich DNA, similar to the G-quadruplex structures that guanine-rich DNA forms. C-rich DNA regions are common in gene regulation portions of the genome. Recently, i-motifs were discovered in human cells and were shown to play a role in cell reproduction. I-motifs have potential applications in nanotechnology and nanomedicine due to their unique pH
Extrachromosomal DNA that cell matures and expands, containing fully mature plastids. Extrachromosomal circular DNA (eccDNA) is present in all eukaryotic cells, is usually derived from genomic DNA, and consists of repetitive sequences of DNA found in both coding and non-coding regions of chromosomes. EccDNA can vary in size from less than 2000 base pairs to more than 20,000 base pairs. In plants, eccDNA contains repeated sequences similar to those that are found in the centromeric regions of the chromosomes and in repetitive satellite DNA. In animals, eccDNA molecules have been shown to contain repetitive sequences that are seen in satellite DNA, 5S