Recreational drug use are caused by an excessive response of the body to allergens, such as the pollen released by grasses and trees. An allergic reaction causes release of histamine by the body. Other uses of antihistamines are to help with normal symptoms of insect stings even if there is no allergic reaction. Their recreational appeal exists mainly due to their anticholinergic properties, that induce anxiolysis and, in some cases such as diphenhydramine, chlorpheniramine, and orphenadrine, a characteristic euphoria at moderate doses. High dosages taken to induce recreational drug effects may lead to overdoses. Antihistamines are also consumed in combination with alcohol, particularly
Bee pollen by herbalists as a treatment for a variety of medical conditions, but there is no good evidence that bee pollen has any health benefits other than as a source of nutrition. Potential risks of consuming bee pollen include contamination by fungal mycotoxins, pesticides, or toxic metals. Bee pollen is safe for short term use, but for those with pollen allergies, allergic reactions may occur (shortness of breath, hives, swelling, and anaphylaxis). Bee pollen is not safe for pregnant women and should not be used during breastfeeding. The Food and Drug Administration has warned against the use of some bee pollen