Salicylic acid Salicylic acid Salicylic acid (from Latin "salix", "willow tree") is a lipophilic monohydroxybenzoic acid, a type of phenolic acid, and a beta hydroxy acid (BHA). It has the formula CHO. This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone. It is derived from the metabolism of salicin. In addition to serving as an important active metabolite of aspirin ("acetylsalicylic acid"), which acts in part as a prodrug to salicylic acid, it is probably best known for its use as a key ingredient in topical anti-acne products. The salts and esters of salicylic
Aminohippuric acid was given along with penicillin in order to prolong the time penicillin circulated in the blood. Because both penicillin and "para"-aminohippurate compete for the same transporter in the kidney, administering "para"-aminohippurate with penicillin decreased the clearance of penicillin from the body by the kidney, providing better antibacterial therapy. Transporters found in the kidney eliminate organic anions and cations from the blood by moving substances, in this case, drug metabolites, from blood into urine. In vultures, the NSAID diclofenac, which is extraordinarily toxic to vultures, interferes with the renal transport of uric acid via the PAH channel. p"K" = 3.83 Aminohippuric