Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
Valerian Gracias of the Republic of India, on 26 January 1966. Valerian Gracias Valerian Gracias (23 October 1900 – 11 September 1978) was an Indian Cardinal of the Roman Catholic Church. He served as Archbishop of Bombay from 1950 until his death and was elevated to the rank of cardinal in 1953 by Pope Pius XII. Valerian Gracias was born in Karachi, British India (in modern Pakistan), to José (d. 1902) and Carlota Gracias. His parents were from Dramapur/Navelim, Goa, working in Karachi. He studied at St. Patrick's High School in Karachi, St. Joseph Seminary in Mangalore, and the Pontifical Seminary of