Valerian (herb) some affinity for the GABA receptor, a class of receptors on which benzodiazepines are known to act. Valeric acid, which is responsible for the typical odor of mostly older valerian roots, does not have any sedative properties. Valeric acid is related to valproic acid, a widely prescribed anticonvulsant; valproic acid is a derivative of valeric acid. Valerian also contains isovaltrate, which has been shown to be an inverse agonist for adenosine A receptor sites. This action likely does not contribute to the herb's possible sedative effects, which would be expected from an agonist, rather than an inverse agonist, at this
They Don't Make Them Like They Used To #2. Two singles came from the album. The title cut, released at the end of 1986, only made #53 in the country charts although it did well by hitting #10 on the contemporary charts. When RCA released "Twenty Years Ago" in 1987, however, Rogers returned to the top five at #2, matching this feat in Canada as well. They Don't Make Them Like They Used To They Don't Make Them Like They Used To (also referred to as "They Don't Make 'Em...") is the nineteenth studio album by country superstar Kenny Rogers. The album's title cut was used as the