Bone still cartilaginous. The following steps are followed in the conversion of cartilage to bone: Bones have a variety of functions: Bones serve a variety of mechanical functions. Together the bones in the body form the skeleton. They provide a frame to keep the body supported, and an attachment point for skeletal muscles, tendons, ligaments and joints, which function together to generate and transfer forces so that individual body parts or the whole body can be manipulated in three-dimensional space (the interaction between bone and muscle is studied in biomechanics). Bones protect internal organs, such as the skull protecting the brain
Bone pain (C fiber) sensory neurons. In combination, they can provide an initial burst of pain, initiated by the faster myelinated fibers, followed by a slower and longer-lasting dull pain initiated by unmyelinated fibers. Nociceptors responsible for bone pain can be activated via several mechanisms including deterioration of surrounding tissue, bone destruction, and physical stress which shears the bone, vascular, muscle, and nervous tissue. Common causes of bone and joint pain in adults, such as osteoarthritis and gouty arthritis are rare in children, as these diseases are a sequelae of chronic wear and tear for several years. The use of anesthetics within