Glycogen debranching enzyme at Duke University suggest that the human AGL gene contains at minimum 2 promotor regions, sites where the transcription of the gene begins, that result in differential expression of isoform, different forms of the same protein, mRNAs in a manner that is specific for different tissues. When GDE activity is compromised, the body cannot effectively release stored glycogen, type III Glycogen Storage Disease (debrancher deficiency), an autosomal recessive disorder, can result. In GSD III glycogen breakdown is incomplete and there is accumulation of abnormal glycogen with short outer branches. Most patients exhibit GDE defiency in both liver and muscle (TypeIIIa),
The body in traditional Chinese medicine trunk, and ends under the collarbone. (2)The Bladder, a Yang organ, stores and removes fluid from the body by receiving Kidney chi. Imbalance of the Bladder leads to frequent or uncontrolled urination. The Bladder Meridian begins in the corner of the eye, moves down the back, and ends on the back of the knee. The Bladder also has another line, which starts alongside the previous line, moves down to the outer edge of the foot and ends on the small toe. The body in traditional Chinese medicine The model of the body in traditional Chinese medicine (TCM) has the following