Protein signalling in heart development Protein signalling in heart development The heart is the first functional organ in a vertebrate embryo. There are 5 stages to heart development. Specification of cardiac precursor cells: The lateral plate mesoderm delaminates to form two layers: the dorsal somatic (parietal) mesoderm and the ventral splanchnic (visceral) mesoderm. The heart precursor cells come from the two regions of the splanchnic mesoderm called the cardiogenic mesoderm. These cells can differentiate into endocardium which lines the heart chamber and valves and the myocardium which forms the musculature of the ventricles and the atria. The heart cells are specified in anterior mesoderm by
Lateral ventricles lateral ventricle and the thalamus; this cleft constitutes the lower part of the choroid fissure. The thalamus primarily communicates with the structures bounding the lateral ventricles via the globus pallidus, and the anterior extremities of the fornix (the mamillary bodies). The lateral ventricles, similarly to other parts of the ventricular system of the brain, develop from the central canal of the neural tube. Specifically, the lateral ventricles originate from the portion of the tube that is present in the developing prosencephalon, and subsequently in the developing telencephalon. During the first three months of prenatal development, the central canal expands into