Androgen receptor the development and maintenance of the male sexual phenotype. In some cell types, testosterone interacts directly with androgen receptors, whereas, in others, testosterone is converted by 5-alpha-reductase to dihydrotestosterone, an even more potent agonist for androgen receptor activation. Testosterone appears to be the primary androgen receptor-activating hormone in the Wolffian duct, whereas dihydrotestosterone is the main androgenic hormone in the urogenital sinus, urogenital tubercle, and hair follicles. Hence, testosterone is responsible primarily for the development of male primary sexual characteristics, whereas dihydrotestosterone is responsible for secondary male characteristics. Androgens cause slow epiphysis, or maturation of the bones, but more of
Sexual Preference (book) Sexual Preference (book) Sexual Preference: Its Development in Men and Women (1981) is a book about the development of sexual orientation by the psychologist Alan P. Bell and the sociologists Martin S. Weinberg and Sue Kiefer Hammersmith, in which the authors reevaluate what were at the time of its publication widely held ideas about the origins of heterosexuality and homosexuality, sometimes rejecting entirely the factors proposed as causes, and in other cases concluding that their importance had been exaggerated. Produced with the help of the American National Institute of Mental Health, the study was a publication of the Institute for