Relapse levels and a decrease in estradiol levels during the luteal phase. Anxiety, irritability, and depression, three symptoms of both withdrawal and the human menstrual cycle, are most severe in the luteal phase. Symptoms of withdrawal not associated with the cycle, such as hunger, are also enhanced during the luteal phase, which suggests the role of estradiol and progesterone in enhancing symptoms above the naturally occurring level of the menstrual cycle. The symptoms of craving also increase during the luteal phase in humans (it is important to note that the opposite result occurs in female subjects with cocaine addiction suggesting that
Menstrual synchrony of northwestern California, according to one ethnographic study, "all of a household's fertile women who were not pregnant menstruated at the same time..." The phenomenon of menstrual synchrony is the closeness in time of the menstrual cycle onsets of two or more women. The phenomenon is not synchronization in the strict sense of concordance of menstrual cycle onsets but the term "menstrual synchrony" is still used perhaps misleadingly. As an undergraduate, Martha McClintock published the first study on menstrual synchrony; her report detailed the menstrual synchrony of undergraduate women living in a dormitory in Wellesley College. Since then, there have