Antibiotic improve treatment outcome as the combined effect of both antibiotics is better than their individual effect. Methicillin-resistant Staphylococcus aureus infections may be treated with a combination therapy of fusidic acid and rifampicin. Antibiotics used in combination may also be antagonistic and the combined effects of the two antibiotics may be less than if the individual antibiotic was given as part of a monotherapy. For example, chloramphenicol and tetracyclines are antagonists to penicillins and aminoglycosides. However, this can vary depending on the species of bacteria. In general, combinations of a bacteriostatic antibiotic and bactericidal antibiotic are antagonistic. Antibiotics are commonly classified
Antibiotic properties of nanoparticles enhanced or induced with the addition of organic drugs. Gold particles, while not inherently antimicrobial, were discovered to express antimicrobial properties when functionalized with ampicillin. In addition to this, gold nanoparticles demonstrated improved membrane permeability with the addition of 4,6-diamino-2-pyrimidenthiol (DAPT) and non-antiobiotic amines (NAA) to their surfaces. Antibiotic properties of nanoparticles Nanoparticles have been studied extensively for their antimicrobial properties in order to fight super bug bacteria. Several characteristics in particular make nanoparticles strong candidates as a traditional antibiotic drug alternative. Firstly, they have a high surface area to volume ratio, which increases contact area with target organisms. Secondly,