Atmosphere of Earth International Space Station orbits in this layer, between . The mesosphere is the third highest layer of Earth's atmosphere, occupying the region above the stratosphere and below the thermosphere. It extends from the stratopause at an altitude of about to the mesopause at above sea level. Temperatures drop with increasing altitude to the mesopause that marks the top of this middle layer of the atmosphere. It is the coldest place on Earth and has an average temperature around . Just below the mesopause, the air is so cold that even the very scarce water vapor at this altitude can be
International Day for the Preservation of the Ozone Layer of the hole in the ozone layer was observed 30 years after the protocol was signed. Due to the nature of the gases responsible for ozone depletion their chemical effects are expected to continue for between 50 to 100 years. International Day for the Preservation of the Ozone Layer September 16 was designated by the United Nations General Assembly as the International Day for the Preservation of the Ozone Layer. This designation had been made on December 19, 2000, in commemoration of the date, in 1987, on which nations signed the Montreal Protocol on Substances that Deplete the Ozone Layer.