Insulin oscillation oscillations. The insulin oscillations are generated by pulsatile release of the hormone from the pancreas. Insulin originates from beta cells located in the islets of Langerhans. Since each islet contains up to 2000 beta cells and there are one million islets in the pancreas it is apparent that pulsatile secretion requires sophisticated synchronization both within and among the islets of Langerhans. Pulsatile insulin secretion from individual beta cells is driven by oscillation of the calcium concentration in the cells. In beta cells lacking contact, the periodicity of these oscillations is rather variable (2-10 min). However, within an islet of Langerhans
Ryan Langerhans RBIs, and 19 stolen bases. In 2000, Langerhans was assigned to the Class-A Advanced Myrtle Beach Pelicans of the Carolina League. He appeared in 116 games with the Pelicans and batted .212 with 14 doubles, 7 triples, 6 home runs, 37 RBIs, and 25 stolen bases. Langerhans's 7 triples was tied for third most in the league with Choo Freeman (7), was and behind Damione Merriman (9), and Chone Figgins (14). Langerhans continued playing with the Class-A Advanced Myrtle Beach Pelicans in 2001. He batted .287 with 30 doubles, 3 triples, 7 home runs, 48 RBIs, and 22 stolen bases.