Valerian (herb) particular binding site. Hydrophilic extractions of the herb commonly sold over the counter, however, probably do not contain significant amounts of isovaltrate. Valerenic acid in valerian stimulates serotonin receptors as a partial agonist, including 5-HT which is implicated in the sleep-wake cycle. The chief constituent of valerian is a yellowish-green to brownish-yellow oil present in the dried root, varying in content from 0.5 to 2.0%. This variation in quantity may be determined by location; a dry, stony soil yields a root richer in oil than moist, fertile soil. The volatile oils that form the active ingredient are pungent, somewhat reminiscent
Valerian Madatov Lieutenant General. He concluded his career fighting the Turks once again on the Danube during the Russo-Turkish War, 1828-1829. On September 4, 1829, two days after the signing of a peace treaty that ended the war, Madatov died from a pulmonary disease, which was sharply aggravated as a result of the burdens of marching during the war. His remains are interred at the Alexander Nevsky Lavra in Saint Petersburg. Valerian Madatov Prince Valerian Grigoryevich Madatov (, , Rostom Madatyan) (1782 – September 4, 1829) was a Russian prince and a lieutenant-general of the Russian Empire. Madatov was born Rostom Madatyan