History of aspirin Peto convinced the U.S. FDA and much of the medical community that the aspirin studies, in aggregate, showed aspirin's effectiveness with relative certainty. By the end of the 1980s, aspirin was widely used as a preventive drug for heart attacks and had regained its former position as the top-selling analgesic in the U.S. History of aspirin The history of aspirin (IUPAC name acetylsalicylic acid ) begins with its synthesis and manufacture in 1899. Before that, salicylic acid had been used medicinally since antiquity. Medicines made from willow and other salicylate-rich plants appear in clay tablets from ancient Sumer as well
Polyacrylic acid of PAA have been prepared that are responsive to pH and temperature stimuli, demonstrating the possibility to be used for drug delivery purposes. ATRP has been used to growth PAA brushes from the surface. One reported approach was with surface-initiated ATRP of tert-butyl acrylate that was subsequently deprotected through pyrolysis to form the carboxylic acid. These PAA brushes can form chelate complex with silver and can therefore exhibit antibacterial activity. Polyacrylic acid Poly(acrylic acid) (PAA; trade name Carbomer) is a synthetic high-molecular weight polymers of acrylic acid. The IUPAC name is poly(1-carboxyethylene. They may be homopolymers of acrylic acid, or