Glycogen synthase regulating glycogen/glucose levels and is activated by dephosphorylation. In humans, there are two paralogous isozymes of glycogen synthase: The liver enzyme expression is restricted to the liver, whereas the muscle enzyme is widely expressed. Liver glycogen serves as a storage pool to maintain the blood glucose level during fasting, whereas muscle glycogen synthesis accounts for disposal of up to 90% of ingested glucose. The role of muscle glycogen is as a reserve to provide energy during bursts of activity. Meanwhile, the muscle isozyme plays a major role in the cellular response to long-term adaptation to hypoxia. Notably, hypoxia only induces
Love in Excess; or, The Fatal Enquiry included several prefatory poems. The poems flatter Haywood's narrative skills and her ability to present "the power of physical and emotional love". The poems that were published in the early editions praised "Love in Excess", but in the 6 edition, they also noticed Haywood's body of work, suggesting her higher reputation as a writer. Positive reaction to her work influenced more women to publish. (109-110) Love in Excess; or, The Fatal Enquiry Love in Excess (1719–1720) is Eliza Haywood's best known novel. It details the amorous escapades of Count D'Elmont, a rake who becomes reformed over the course of the