Tooth discoloration decomposed gradually and a blue-brown discoloration develops. Teeth may turn grey following trauma-induced pulp necrosis (death of the pulp). This discoloration typically develops weeks or months after the injury and is caused by incorporation of pigments released during the breakdown of the pulpal tissue and blood into the dentin. Yellow discoloration may occur following pulp canal obliteration, i.e., the sealing up of the pulp. Trauma to a developing adult tooth (e.g., intrusion of a baby tooth into the bone) may affect the enamel layer of the adult tooth. This becomes apparent when the adult tooth erupts into the mouth. Teeth
Human tooth development through cementum. NGF-R is present in the condensing ectomesenchymal cells of the dental papilla in the early cap stage tooth germ and plays multiple roles during morphogenetic and cytodifferentiation events in the tooth. There is a relationship between tooth agenesis and absence of the peripheral trigeminal nerve (see Hypodontia). All stages (bud, cap, bell, crown), growth and morphogenesis of the teeth are regulated by a protein called sonic hedgehog. Various phenotypic inputs modulate the size of the teeth. Parathyroid hormone is required for tooth eruption. The following tables present the development timeline of human teeth. Times for the initial calcification