Multiple endocrine neoplasia type 1 symptoms. These disorders greatly increase the risk of developing multiple cancerous and noncancerous tumors in glands such as the parathyroid, pituitary, and pancreas. Multiple endocrine neoplasia occurs when tumors are found in at least two of the three main endocrine glands (parathyroid, pituitary, and pancreatico-duodenum). Tumors can also develop in organs and tissues other than endocrine glands. If the tumors become cancerous, some cases can be life-threatening. The disorder affects 1 in 30,000 people. Although many different types of hormone-producing tumors are associated with multiple endocrine neoplasia, tumors of the parathyroid gland, pituitary gland, and pancreas are most frequent in
Endocrine surgery performed by surgeons who do at least 100 thyroid operations per year.In the United Kingdom most thyroid surgery is performed by surgeons doing less than 20 thyroid operations per year. This results in a high risk of permanent voice change (up to 2%) and a high risk of parathyroid damage. In expert hands these risks should be nearer 0.5%.Permanent damage to both voice box nerves is an extreme rarity and needs in most cases a permanent tracheotomy. Endocrine surgery Endocrine surgery is a surgical sub-speciality focusing on surgery of the endocrine glands, including the thyroid gland, the parathyroid glands, the