Valerian (herb) particular binding site. Hydrophilic extractions of the herb commonly sold over the counter, however, probably do not contain significant amounts of isovaltrate. Valerenic acid in valerian stimulates serotonin receptors as a partial agonist, including 5-HT which is implicated in the sleep-wake cycle. The chief constituent of valerian is a yellowish-green to brownish-yellow oil present in the dried root, varying in content from 0.5 to 2.0%. This variation in quantity may be determined by location; a dry, stony soil yields a root richer in oil than moist, fertile soil. The volatile oils that form the active ingredient are pungent, somewhat reminiscent
Valerian A. Frolov Valerian A. Frolov Valerian Aleksandrovich Frolov (; June 7 (O.S. May 26), 1895 – 1961) was a Soviet Colonel General (1943). Frolov participated in the First World War, the Russian Civil War, and the Soviet-Finnish war as an Army commander, and during the Second World War as the commander of the 14th Army, and from September 1941 to February 1944, the Karelian Front. After the war from 1945 to 1956 commanded the troops of Belomorsky Military District and Arkhangelsk Military District. From 1956 he was placed in reserve. Valerian Frolov was awarded three Orders of Lenin, four Orders of the