Endocrine disruptor own hormones. These regulation effects are intertwined so that a hormone that is level affected by another hormone in turn affects the levels of multiple other hormones produced by the body itself, leaving no endogenous hormones or traits affected by them unaffected by endocrine disruptors. Most toxicants, including endocrine disruptors, have been claimed to follow a U-shaped dose response curve. This means that very low and very high levels have more effects than mid-level exposure to a toxicant. Endocrine disrupting effects have been noted in animals exposed to environmentally relevant levels of some chemicals. For example, a common flame retardant,
European Chemicals Agency as well as substances which persist in the body or the environment and do not break down. Other substances considered as SVHCs include, for example, endocrine disrupting chemicals. Companies manufacturing or importing articles containing these substances in a concentration above 0,1% weight of the article, have legal obligations. They are required to inform users about the presence of the substance and therefore how to use it safely. Consumers have the right to ask the retailer whether these substances are present in the products they buy. Once a substance has been officially identified in the EU as being of very high