Recreational drug use are caused by an excessive response of the body to allergens, such as the pollen released by grasses and trees. An allergic reaction causes release of histamine by the body. Other uses of antihistamines are to help with normal symptoms of insect stings even if there is no allergic reaction. Their recreational appeal exists mainly due to their anticholinergic properties, that induce anxiolysis and, in some cases such as diphenhydramine, chlorpheniramine, and orphenadrine, a characteristic euphoria at moderate doses. High dosages taken to induce recreational drug effects may lead to overdoses. Antihistamines are also consumed in combination with alcohol, particularly
Pollen cell. In flowering plants the vegetative tube cell produces the pollen tube, and the generative cell divides to form the two sperm cells. Pollen is produced in the microsporangia in the male cone of a conifer or other gymnosperm or in the anthers of an angiosperm flower. Pollen grains come in a wide variety of shapes, sizes, and surface markings characteristic of the species (see electron micrograph, right). Pollen grains of pines, firs, and spruces are winged. The smallest pollen grain, that of the forget-me-not ("Myosotis" spp.), is around 6 µm (0.006 mm) in diameter. Wind-borne pollen grains can be