Versican other inflammatory cells) can migrate more easily through extracellular matrix that has a higher versican content. Deposits of versican are not present in normal skin but are found in the reticular dermis during keloid scarring, a condition where scar formation becomes uncontrolled and overgrowth of skin tissue occurs at the site of the wound. Versican has been shown to interact with hyaluronan and a link protein (hyaluronan and proteoglycan link protein 1; HAPLN1). Versican Versican is a large extracellular matrix proteoglycan that is present in a variety of human tissues. It is encoded by the "VCAN" gene. Versican is a
Scar Tissue Scar Tissue "Scar Tissue" is the first single from the American rock band Red Hot Chili Peppers' seventh studio album "Californication", released in 1999. It is one of their most successful songs, spending a then-record 16 consecutive weeks on top of the "Billboard" Hot Modern Rock Tracks chart, as well as 10 weeks at the top of the "Billboard" Mainstream Rock Tracks chart and reached number eight on "Billboard" Hot 100 Airplay. It peaked at number nine on the "Billboard" Hot 100. In the UK, the song reached number 15 on the UK Singles Chart. It was also successful in