History of aspirin Peto convinced the U.S. FDA and much of the medical community that the aspirin studies, in aggregate, showed aspirin's effectiveness with relative certainty. By the end of the 1980s, aspirin was widely used as a preventive drug for heart attacks and had regained its former position as the top-selling analgesic in the U.S. History of aspirin The history of aspirin (IUPAC name acetylsalicylic acid ) begins with its synthesis and manufacture in 1899. Before that, salicylic acid had been used medicinally since antiquity. Medicines made from willow and other salicylate-rich plants appear in clay tablets from ancient Sumer as well
Pyrophosphoric acid red heat of a sodium phosphate salt. It was found that phosphoric acid when heated to red heat formed pyrophosphoric acid that was readily converted to phosphoric acid by hot water. Pyrophosphoric acid Pyrophosphoric acid, also known under the name diphosphoric acid, is colorless, odorless, hygroscopic and is soluble in water, diethyl ether, and ethyl alcohol. The anhydrous acid has two different forms, which melt at 54.3 °C and 71.5 °C. It is best prepared by ion exchange from sodium pyrophosphate or by reacting hydrogen sulfide with lead pyrophosphate. When phosphoric acid is dehydrated pyrophosphoric acid is produced as one