Atmosphere of Earth International Space Station orbits in this layer, between . The mesosphere is the third highest layer of Earth's atmosphere, occupying the region above the stratosphere and below the thermosphere. It extends from the stratopause at an altitude of about to the mesopause at above sea level. Temperatures drop with increasing altitude to the mesopause that marks the top of this middle layer of the atmosphere. It is the coldest place on Earth and has an average temperature around . Just below the mesopause, the air is so cold that even the very scarce water vapor at this altitude can be
Ozone only in low concentrations. Ozone is a powerful oxidant (far more so than dioxygen) and has many industrial and consumer applications related to oxidation. This same high oxidising potential, however, causes ozone to damage mucous and respiratory tissues in animals, and also tissues in plants, above concentrations of about . While this makes ozone a potent respiratory hazard and pollutant near ground level, a higher concentration in the ozone layer (from two to eight ppm) is beneficial, preventing damaging UV light from reaching the Earth's surface. The trivial name "ozone" is the most commonly used and preferred IUPAC name. The