Light skin of UVA can penetrate deeply into the dermis in persons with light skin pigmentation with little protective melanin pigment. The characteristic of fair skin, red hair, and freckling is associated with high amount of pheomelanin, little amounts of eumelanin. This phenotype is caused by a loss-of-function mutation in the melanocortin 1 receptor (MC1R) gene. However, variations in the MC1R gene sequence only have considerable influence on pigmentation in populations where red hair and extremely fair skin is prevalent. The gene variation’s primary effect is to promote eumelanin synthesis at the expense of pheomelanin synthesis, although this contributes to very little
Pigment pigment derived from a parasitic insect found in Central and South America—attained great status and value in Europe. Produced from harvested, dried, and crushed cochineal insects, carmine could be—and still is—used in fabric dye, food dye, body paint, or—in its solid lake form—almost any kind of paint or cosmetic. According to Diana Magaloni, the Florentine Codex contains a variety of illustrations with multiple variations of the red pigments. Specifically in the case of "achiotl (light red)," technical analysis of the paint reveals multiple layers of the pigment although the layers of the pigment is not visible to the naked eye.