Kidney transplantation is required. Most people need two or three such injections, and many are not completely insulin-free. The transplant surgery takes about three hours. The donor kidney will be placed in the lower abdomen and its blood vessels connected to arteries and veins in the recipient's body. When this is complete, blood will be allowed to flow through the kidney again. The final step is connecting the ureter from the donor kidney to the bladder. In most cases, the kidney will soon start producing urine. Depending on its quality, the new kidney usually begins functioning immediately. Living donor kidneys normally require
Bladder pipe into the bladder. While the first creation of a double reed pipe with a bladder controlling breath is unknown, it is believed to have originated in Europe before the 13th century. As an intermediate phase between the almost pan-European bagpipe and the Renaissance crumhorn, the Bladder pipe flourished from the 14th to 16th centuries. Examples have been found from Germany, Poland, England, France, Italy, Spain (called the odrecillo) and Estonia (called the rakkopilli). As it declined in popularity, it became associated with beggars and peasants. The early bladder pipe is in a family of the early medieval "chorus" instruments, a