Digestion (largely the glucose-insulin system) have been uncovered in recent years. Digestion is a complex process controlled by several factors. pH plays a crucial role in a normally functioning digestive tract. In the mouth, pharynx and esophagus, pH is typically about 6.8, very weakly acidic. Saliva controls pH in this region of the digestive tract. Salivary amylase is contained in saliva and starts the breakdown of carbohydrates into monosaccharides. Most digestive enzymes are sensitive to pH and will denature in a high or low pH environment. The stomach's high acidity inhibits the breakdown of carbohydrates within it. This acidity confers two
Calponin 3, acidic in mouse CC myoblasts inhibited cell fusion during "in vitro" differentiation, whereas "Cnn3" gene knockdown promoted cell fusion and the expression of skeletal muscle myosin. The inhibitory effect of calponin 3 was reversed upon phosphorylation by Rho-associated kinase 1/2 (ROCK1/2). Calponin 3, acidic Calponin 3. acidic is a protein that in humans is encoded by the "CNN3" gene. The "CNN3" gene is located at 1p22-p21 in the human chromosomal genome. "CNN3" gene contains 7 exons and encodes calponin 3, a 36.4-kDa protein consisting of 329 amino acids with isoelectric point (pI) of 5.84. Calponin 3 is known as acidic calponin.