Glycogen debranching enzyme at Duke University suggest that the human AGL gene contains at minimum 2 promotor regions, sites where the transcription of the gene begins, that result in differential expression of isoform, different forms of the same protein, mRNAs in a manner that is specific for different tissues. When GDE activity is compromised, the body cannot effectively release stored glycogen, type III Glycogen Storage Disease (debrancher deficiency), an autosomal recessive disorder, can result. In GSD III glycogen breakdown is incomplete and there is accumulation of abnormal glycogen with short outer branches. Most patients exhibit GDE defiency in both liver and muscle (TypeIIIa),
Love in Excess; or, The Fatal Enquiry included several prefatory poems. The poems flatter Haywood's narrative skills and her ability to present "the power of physical and emotional love". The poems that were published in the early editions praised "Love in Excess", but in the 6 edition, they also noticed Haywood's body of work, suggesting her higher reputation as a writer. Positive reaction to her work influenced more women to publish. (109-110) Love in Excess; or, The Fatal Enquiry Love in Excess (1719–1720) is Eliza Haywood's best known novel. It details the amorous escapades of Count D'Elmont, a rake who becomes reformed over the course of the