Progesterone nervous tissue, especially in the brain, and in adipose (fat) tissue, as well. During human pregnancy, progesterone is produced in increasingly high amounts by the ovaries and placenta. At first, the source is the corpus luteum that has been "rescued" by the presence of human chorionic gonadotropin (hCG) from the conceptus. However, after the 8th week, production of progesterone shifts to the placenta. The placenta utilizes maternal cholesterol as the initial substrate, and most of the produced progesterone enters the maternal circulation, but some is picked up by the fetal circulation and used as substrate for fetal corticosteroids. At term
Menstrual cup investigated whether silicone menstrual cups are a viable alternative to tampons and found that approximately 91% of women in the menstrual cup group said they would continue to use the cup and recommend it to others. In a 1991 clinical study involving 51 women, 23 of the participants (45%) found rubber menstrual cups to be an acceptable way of managing menstrual flow. In a randomized controlled feasibility study in rural western Kenya, adolescent primary school girls were provided with menstrual cups or sanitary pads instead of traditional menstrual care items of cloth or tissue. Girls provided with menstrual cups had