Toxicodynamics into awareness by Our Stolen Future by Theo Colborn. Endocrine disrupting chemicals are known to accumulate in body tissue and are highly persistent in the environment. Many toxicants are known EDCs including pesticides, phthalates, phytoestrogens, some industrial/commercial products, and pharmaceuticals. These chemicals are known to cause endocrine disruption via a few different mechanisms. While the mechanism associated with the thyroid hormone receptor is not well understood, two more established mechanisms involve the inhibition of the androgen receptor and activation of the estrogen receptor. Certain toxicants act as endocrine disruptors by interacting with the androgen receptor. DDE is one example of
Endocrine surgery Endocrine surgery Endocrine surgery is a surgical sub-speciality focusing on surgery of the endocrine glands, including the thyroid gland, the parathyroid glands, the adrenal glands, glands of the endocrine pancreas, and some neuroendocrine glands. Surgery of the thyroid gland constitutes the bulk of endocrine surgical procedures worldwide. This may be done for a variety of conditions, ranging from benign multinodular goiter to thyroid cancer.In the United Kingdom it was developed as a separate speciality from general surgery at the Royal Postgraduate Medical School by Dick Welbourne and John Lynn. Operations involve removal of the thyroid gland (thyroidectomy) either as a