Atmosphere of Earth International Space Station orbits in this layer, between . The mesosphere is the third highest layer of Earth's atmosphere, occupying the region above the stratosphere and below the thermosphere. It extends from the stratopause at an altitude of about to the mesopause at above sea level. Temperatures drop with increasing altitude to the mesopause that marks the top of this middle layer of the atmosphere. It is the coldest place on Earth and has an average temperature around . Just below the mesopause, the air is so cold that even the very scarce water vapor at this altitude can be
Ozone depletion spectrophotometers led an international panel to conclude that the ozone layer was in fact being depleted, at all latitudes outside of the tropics. These trends were confirmed by satellite measurements. As a consequence, the major halocarbon-producing nations agreed to phase out production of CFCs, halons, and related compounds, a process that was completed in 1996. Since 1981 the United Nations Environment Programme, under the auspices of the World Meteorological Organization, has sponsored a series of technical reports on the Scientific Assessment of Ozone Depletion, based on satellite measurements. The 2007 report showed that the hole in the ozone layer was