Endocrine disruptor own hormones. These regulation effects are intertwined so that a hormone that is level affected by another hormone in turn affects the levels of multiple other hormones produced by the body itself, leaving no endogenous hormones or traits affected by them unaffected by endocrine disruptors. Most toxicants, including endocrine disruptors, have been claimed to follow a U-shaped dose response curve. This means that very low and very high levels have more effects than mid-level exposure to a toxicant. Endocrine disrupting effects have been noted in animals exposed to environmentally relevant levels of some chemicals. For example, a common flame retardant,
Multiple endocrine neoplasia is a genetic disorder characterized by endocrine neoplastic features involving endocrine glands that overlap with those involved in MEN1 or MEN2. Percentages in table below refer to how large fraction of people with the MEN type develop the neoplasia type. <nowiki>*</nowiki>- of patients with MEN1 and gastrinoma FMTC = familial medullary thyroid cancer MEN 2B is sometimes known as MEN 3 and the designation varies by institution (c.f. www.ClinicalReview.com). Although a variety of additional eponyms have been proposed for MEN2B (e.g. Williams-Pollock syndrome, Gorlin-Vickers syndrome, and Wagenmann–Froboese syndrome), none ever gained sufficient traction to merit continued use and, indeed, are