Extrachromosomal Circular DNA are composed of chromatin and replicate in the nucleus of the cell during cell division. Unlike typical chromosomes, they are composed of circular fragments of DNA, up to only a few million base pairs in size and contain no centromere or telomere. Extrachromosomal Circular DNA Extrachromosomal circular DNA (eccDNA) is circular DNA found in the nuclei of plant and animal cells, including human cells, in addition to chromosomal DNA. eccDNA can be from 200 up to 5 million base pairs in length. eccDNA has been found in the nuclei of human cancer cells and shown to carry many copies of
Nuclear DNA mitochondrial DNA is haploid, coming only from the mother. The mutation rate for nuclear DNA is less than 0.3% while that of mitochondrial DNA is generally higher. Nuclear DNA is known as the molecule of life and contains the genetic instructions for the development of all living organisms. It is found in almost every cell in the human body, with exceptions such as red blood cells. Everyone has a unique genetic blueprint, even identical twins. Forensic departments such as the Bureau of Criminal Apprehension (BCA) and Federal Bureau of Investigation (FBI) are able to use techniques involving nuclear DNA to