Enrico Fermi to be nuclear fission products. Fermi left Italy in 1938 to escape new Italian racial laws that affected his Jewish wife, Laura Capon. He emigrated to the United States, where he worked on the Manhattan Project during World War II. Fermi led the team that designed and built Chicago Pile-1, which went critical on 2 December 1942, demonstrating the first human-created, self-sustaining nuclear chain reaction. He was on hand when the X-10 Graphite Reactor at Oak Ridge, Tennessee, went critical in 1943, and when the B Reactor at the Hanford Site did so the next year. At Los Alamos, he
Enrico Fermi a much larger scale. Fermi and Szilárd collaborated on a design of a device to achieve a self-sustaining nuclear reaction—a nuclear reactor. Owing to the rate of absorption of neutrons by the hydrogen in water, it was unlikely that a self-sustaining reaction could be achieved with natural uranium and water as a neutron moderator. Fermi suggested, based on his work with neutrons, that the reaction could be achieved with uranium oxide blocks and graphite as a moderator instead of water. This would reduce the neutron capture rate, and in theory make a self-sustaining chain reaction possible. Szilárd came up with