Nuclear chain reaction the last one called ""Perfectionnement aux charges explosives"" was the first patent for the atomic bomb and is filed as patent n°445686 by the Caisse nationale de Recherche Scientifique. In parallel, Szilárd and Enrico Fermi in New York made the same analysis. This discovery prompted the letter from Szilárd and signed by Albert Einstein to President Franklin D. Roosevelt, warning of the possibility that Nazi Germany might be attempting to build an atomic bomb. On December 2, 1942, a team led by Enrico Fermi produced the first artificial self-sustaining nuclear chain reaction with the Chicago Pile-1 (CP-1) experimental reactor in
Enrico Fermi Nuclear Generating Station of threats to public health and the environment. The groups have filed 14 contentions with the NRC, claiming that a new plant would pose "radioactive, toxic and thermal impacts on Lake Erie's vulnerable western basin." In May 2015, the Nuclear Regulatory Commission approved a combined construction and operating license for Fermi 3, but DTE Energy stated there were no plans for construction at that time. The Nuclear Regulatory Commission's 2010 estimate of the risk each year of an earthquake intense enough to cause core damage to the reactor at Fermi was 1 in 238,095 making it the 88th least likely