Enrico Fermi and moved to the Argonne Woods site. There Fermi directed experiments on nuclear reactions, revelling in the opportunities provided by the reactor's abundant production of free neutrons. The laboratory soon branched out from physics and engineering into using the reactor for biological and medical research. Initially, Argonne was run by Fermi as part of the University of Chicago, but it became a separate entity with Fermi as its director in May 1944. When the air-cooled X-10 Graphite Reactor at Oak Ridge went critical on 4 November 1943, Fermi was on hand just in case something went wrong. The technicians woke
Enrico Fermi a much larger scale. Fermi and Szilárd collaborated on a design of a device to achieve a self-sustaining nuclear reaction—a nuclear reactor. Owing to the rate of absorption of neutrons by the hydrogen in water, it was unlikely that a self-sustaining reaction could be achieved with natural uranium and water as a neutron moderator. Fermi suggested, based on his work with neutrons, that the reaction could be achieved with uranium oxide blocks and graphite as a moderator instead of water. This would reduce the neutron capture rate, and in theory make a self-sustaining chain reaction possible. Szilárd came up with