Horn River formed along the middle course of the Horn River, and is followed downstream by the "Second Lake". The river turns south-west, where the "Mink Lake" is formed along its course. The Laferte River also flows into the Mink Lake. Horn River then flows south, and it receives the waters of the Bluefish River before it empties into the Mackenzie River, downstream from the Great Slave Lake), immediately upstream from Mills Lake, at an elevation of . The arch made by the river defines the "Horn Plateau", a flat elevated area that rises up to ) to the north and east,
Mackenzie River the northwest, establishing the present flow direction to the Arctic. Fluvial deposits and other erosional evidence indicate that around the end of the Pleistocene, about 13,000 years ago, the Mackenzie channel was scoured by one or more massive glacial lake outburst floods unleashed from Lake Agassiz, formed by melting ice west of the present-day Great Lakes. At its peak, Agassiz had a greater volume than all present-day freshwater lakes combined. This is believed to have disrupted currents in the Arctic Ocean and led to an abrupt 1,300-year-long cold temperature shift called the Younger Dryas. The Mackenzie carries a very large