Babe Ruth three-run home run off Charlie Root in the first inning, but soon revived, and the Cubs tied the score at 4–4 in the fourth inning. When Ruth came to the plate in the top of the fifth, the Chicago crowd and players, led by pitcher Guy Bush, were screaming insults at Ruth. With the count at two balls and one strike, Ruth gestured, possibly in the direction of center field, and after the next pitch (a strike), may have pointed there with one hand. Ruth hit the fifth pitch over the center field fence; estimates were that it traveled nearly
Barry Bonds May 20, Bonds tied Ruth, hitting his 714th career home run to deep right field to lead off the top of the 2nd inning. The home run came off left-handed pitcher Brad Halsey of the Oakland A's, in an interleague game played in Oakland, California. Since this was an interleague game at an American League stadium, Bonds was batting as the designated hitter in the lineup for the Giants. Bonds was quoted after the game as being "glad it's over with" and stated that more attention could be focused on Albert Pujols, who was on a very rapid home run