Horn River formed along the middle course of the Horn River, and is followed downstream by the "Second Lake". The river turns south-west, where the "Mink Lake" is formed along its course. The Laferte River also flows into the Mink Lake. Horn River then flows south, and it receives the waters of the Bluefish River before it empties into the Mackenzie River, downstream from the Great Slave Lake), immediately upstream from Mills Lake, at an elevation of . The arch made by the river defines the "Horn Plateau", a flat elevated area that rises up to ) to the north and east,
Mackenzie River Lakes are remnants. Today's Mackenzie River is very young in geologic terms – its channel formed over a period of no more than several thousand years as the ice sheet retreated. Prior to the ice ages, only the Peel River tributary flowed through what is now the Mackenzie Delta into the Arctic Ocean. The other tributaries of the Mackenzie combined into the "Bell River" which flowed east into Hudson Bay. During glaciation the weight of the ice sheet depressed northern Canada's terrain to such an extent that when the ice retreated, the Mackenzie system was captured to lower elevations in