Louise de Kérouaille, Duchess of Portsmouth died in Paris on 14 November 1734, aged 85. Some of Louise's descendants, Diana, Princess of Wales, Camilla, Duchess of Cornwall, Sarah, Duchess of York and Princess Alice, Duchess of Gloucester, would eventually play major roles in the lives of later princes of the United Kingdom: Charles, Prince of Wales, Andrew, Duke of York and Prince Henry, Duke of Gloucester. Louise de Kérouaille, Duchess of Portsmouth Louise Renée de Penancoët de Kérouaille, Duchess of Portsmouth (September 1649 – 14 November 1734) was a mistress of Charles II of England. Through her son by Charles II, Charles Lennox, 1st Duke of
Sarah, Duchess of York in Crisis, a children's charity focused on education and grant making to international programmes. The Duchess serves as Founder and Life President. She founded the charity after meeting a young cancer victim named Anya during her visit to Poland in 1992. In June 1998, the Duchess made a brief trip to Bethesda in order to receive an award from the Journal of Women's Health. She also visited the National Institutes of Health (NIH) Clinical Center. NIH associate director for communications said, "The Duchess has many opportunities to talk to women via television, at lectures and through print media interviews" and