Nuclear chain reaction the last one called ""Perfectionnement aux charges explosives"" was the first patent for the atomic bomb and is filed as patent n°445686 by the Caisse nationale de Recherche Scientifique. In parallel, Szilárd and Enrico Fermi in New York made the same analysis. This discovery prompted the letter from Szilárd and signed by Albert Einstein to President Franklin D. Roosevelt, warning of the possibility that Nazi Germany might be attempting to build an atomic bomb. On December 2, 1942, a team led by Enrico Fermi produced the first artificial self-sustaining nuclear chain reaction with the Chicago Pile-1 (CP-1) experimental reactor in
Enrico Fermi resulted in the denial of Oppenheimer's security clearance. Fermi did important work in particle physics, especially related to pions and muons, and he speculated that cosmic rays arose when material was accelerated by magnetic fields in interstellar space. Many awards, concepts, and institutions are named after Fermi, including the Enrico Fermi Award, the Enrico Fermi Institute, the Fermi National Accelerator Laboratory, the Fermi Gamma-ray Space Telescope, the Enrico Fermi Nuclear Generating Station, and the synthetic element fermium, making him one of 16 scientists who have elements named after them. Enrico Fermi was born in Rome, Italy, on 29 September 1901.