Oak Ridge National Laboratory was completed, later renamed to "Oak Ridge National Laboratory". The site was chosen for the X-10 Graphite Reactor, used to show that plutonium can be created from enriched uranium. Enrico Fermi and his colleagues developed the world's second self-sustaining nuclear reactor after Fermi's previous experiment, the Chicago Pile-1. The X-10 was the first reactor designed for continuous operation. After the end of World War II the demand for weapons-grade plutonium fell and the reactor and the laboratory's 1000 employees were no longer involved in nuclear weapons. Instead, it was used for scientific research. In 1946 the first medical isotopes were
Enrico Fermi He made significant contributions to the development of statistical mechanics, quantum theory, and nuclear and particle physics. Fermi's first major contribution was to statistical mechanics. After Wolfgang Pauli formulated his exclusion principle in 1925, Fermi followed with a paper in which he applied the principle to an ideal gas, employing a statistical formulation now known as Fermi–Dirac statistics. Today, particles that obey the exclusion principle are called "fermions". Pauli later postulated the existence of an uncharged invisible particle emitted along with an electron during beta decay, to satisfy the law of conservation of energy. Fermi took up this idea, developing