Nuclear chain reaction the last one called ""Perfectionnement aux charges explosives"" was the first patent for the atomic bomb and is filed as patent n°445686 by the Caisse nationale de Recherche Scientifique. In parallel, Szilárd and Enrico Fermi in New York made the same analysis. This discovery prompted the letter from Szilárd and signed by Albert Einstein to President Franklin D. Roosevelt, warning of the possibility that Nazi Germany might be attempting to build an atomic bomb. On December 2, 1942, a team led by Enrico Fermi produced the first artificial self-sustaining nuclear chain reaction with the Chicago Pile-1 (CP-1) experimental reactor in
Marshall Holloway as a laboratory instrument to test critical mass calculations and the effect of various tamper materials. The Water Boiler group was headed by Donald W. Kerst from the University of Illinois, and the group designed and built the Water Boiler, which achieved its criticality in May 1944 under the control of Enrico Fermi, after one final addition of uranium enriched to 14% uranium 235. It was world third reactor but the first reactor to use enriched uranium as a fuel, using most of the world's supply at the time, and the first to use liquid nuclear fuel in the form