Horn River formed along the middle course of the Horn River, and is followed downstream by the "Second Lake". The river turns south-west, where the "Mink Lake" is formed along its course. The Laferte River also flows into the Mink Lake. Horn River then flows south, and it receives the waters of the Bluefish River before it empties into the Mackenzie River, downstream from the Great Slave Lake), immediately upstream from Mills Lake, at an elevation of . The arch made by the river defines the "Horn Plateau", a flat elevated area that rises up to ) to the north and east,
Mackenzie River which empty into the Pacific Ocean. Lowland divides in the north separate the Mackenzie basin from the Arctic Ocean watersheds of the Anderson, Horton, Coppermine and Back Rivers. In the east, the Mackenzie borders on the Hudson Bay watersheds of the Thelon and Churchill Rivers, and to the south it is bordered by the Saskatchewan–Nelson River system, which also empties into Hudson Bay. The Mackenzie system is hydrologically connected to the Hudson Bay watershed via Wollaston Lake, which is not only the source of the Fond du Lac tributary of Lake Athabasca, but also of the Cochrane River, which flows