Kakisa River a while, then turns east, where it builds a complex lake and channel system before it empties into the Tathlina Lake at its western extremity. It flows out the north side of the lake and continues north, receives the waters of Gull Creek, then flows into the Kakisa Lake at its southern shore. It flows out at the eastern side of the lake, drops through the Lady Evelyn Falls before it is crossed by the Mackenzie Highway. It continues northwards, then empties into the Mackenzie River, downstream from the Great Slave Lake, at an elevation of . Kakisa River The
Mackenzie River and riparian habitat. There are 53 fish species in the basin, none of them endemic. The Mackenzie River has a similar range of fish fauna to the Mississippi River system. It is believed that the two river systems were connected during the Ice Ages by meltwater lakes and channels, allowing fish in the two rivers to interbreed. Fish in the Mackenzie River proper include the northern pike, several minnow species, and lake whitefish. Fish in the southern half of the watershed are genetically isolated from those of the northern half due to large rapids on the Slave River preventing fish