Horn River formed along the middle course of the Horn River, and is followed downstream by the "Second Lake". The river turns south-west, where the "Mink Lake" is formed along its course. The Laferte River also flows into the Mink Lake. Horn River then flows south, and it receives the waters of the Bluefish River before it empties into the Mackenzie River, downstream from the Great Slave Lake), immediately upstream from Mills Lake, at an elevation of . The arch made by the river defines the "Horn Plateau", a flat elevated area that rises up to ) to the north and east,
Mackenzie River watershed, reaching up to deep in the Mackenzie Delta. As a whole, the Mackenzie basin receives only meager to moderate rainfall, averaging over the entire basin, though mountain areas experience much higher precipitation, and areas near and north of the Arctic Circle receive much lower precipitation. The Mackenzie drainage basin is bordered by multiple major North American watersheds. Much of the western edge of the Mackenzie basin runs along the Continental Divide. The divide separates the Mackenzie watershed from that of the Yukon River, which flows to the Bering Strait; and the Fraser River and Columbia River systems, both of