Nuclear chain reaction the last one called ""Perfectionnement aux charges explosives"" was the first patent for the atomic bomb and is filed as patent n°445686 by the Caisse nationale de Recherche Scientifique. In parallel, Szilárd and Enrico Fermi in New York made the same analysis. This discovery prompted the letter from Szilárd and signed by Albert Einstein to President Franklin D. Roosevelt, warning of the possibility that Nazi Germany might be attempting to build an atomic bomb. On December 2, 1942, a team led by Enrico Fermi produced the first artificial self-sustaining nuclear chain reaction with the Chicago Pile-1 (CP-1) experimental reactor in
Enrico Fermi him early so that he could see it happen. Getting X-10 operational was another milestone in the plutonium project. It provided data on reactor design, training for DuPont staff in reactor operation, and produced the first small quantities of reactor-bred plutonium. Fermi became an American citizen in July 1944, the earliest date the law allowed. In September 1944, Fermi inserted the first uranium fuel slug into the B Reactor at the Hanford Site, the production reactor designed to breed plutonium in large quantities. Like X-10, it had been designed by Fermi's team at the Metallurgical Laboratory, and built by DuPont,