Model organism anticonvulsant properties of lithium salts, which revolutionized the treatment of bipolar disorder, replacing the previous treatments of lobotomy or electroconvulsive therapy. Modern general anaesthetics, such as halothane and related compounds, were also developed through studies on model organisms, and are necessary for modern, complex surgical operations. In the 1940s, Jonas Salk used rhesus monkey studies to isolate the most virulent forms of the polio virus, which led to his creation of a polio vaccine. The vaccine, which was made publicly available in 1955, reduced the incidence of polio 15-fold in the United States over the following five years. Albert Sabin
Jonas Salk talks continually about getting out of the limelight and back to his laboratory ... because of his genuine distaste for publicity, which he believes is inappropriate for a scientist." During a 1980 interview, 25 years later, he said, "It's as if I've been a public property ever since, having to respond to external, as well as internal, impulses. ... It's brought me enormous gratification, opened many opportunities, but at the same time placed many burdens on me. It altered my career, my relationships with colleagues; I am a public figure, no longer one of them." "If Salk the scientist sounds