Model organism anticonvulsant properties of lithium salts, which revolutionized the treatment of bipolar disorder, replacing the previous treatments of lobotomy or electroconvulsive therapy. Modern general anaesthetics, such as halothane and related compounds, were also developed through studies on model organisms, and are necessary for modern, complex surgical operations. In the 1940s, Jonas Salk used rhesus monkey studies to isolate the most virulent forms of the polio virus, which led to his creation of a polio vaccine. The vaccine, which was made publicly available in 1955, reduced the incidence of polio 15-fold in the United States over the following five years. Albert Sabin
Salk Institute for Biological Studies becoming greener. The Salk Institute's open environment replete with empty space is symbolic of an open environment for creation, the symmetry stands for scientific precision, and submerging crevasses allow warm, natural light to enter the buildings like the intellectual light that leads to discovery. The contrast between balance and dynamic space manifests a pluralistic invitation for scientific study in structures developed to accommodate their respective functions as parts of a research facility. Although modern in appearance, it is essentially an isolated compound for individual and collaborative study, not unlike monasteries as sanctuaries for religious discovery, and they are thought to