Polio vaccine 900 developed polio; in the group receiving the vaccine, only one out of 7,500 developed polio, making the vaccine 88% effective during the first year. However, other researchers believed that the one case was likely caused by the vaccine, and two more possible cases were reported later. After this meeting, Brodie, whose polio vaccine was at least partially effective and reasonably safe, and who developed several ground-breaking ideas about vaccination whose validity was confirmed two decades later with the development of the Salk vaccine, was immediately fired and had trouble finding employment again. Brodie died three and a half years
Jonas Salk Crick, codiscoverer of the structure of the DNA molecule, was a leading professor at the institute until his death in 2004. The institute also served as the basis for Bruno Latour and Steve Woolgar's 1979 book "Laboratory Life: The Construction of Scientific Facts". Beginning in the mid-1980s, Salk also engaged in research to develop a vaccine for another, more recent plague, AIDS. To further this research, he cofounded the Immune Response Corporation with Kevin Kimberlin, to search for a vaccine, and patented Remune, an immune-based therapy. He was unable to secure product liability Insurance. The AIDS vaccine project was discontinued