Jim Fixx Jim Fixx James Fuller "Jim" Fixx (April 23, 1932 – July 20, 1984) was an American who wrote the 1977 best-selling book "The Complete Book of Running". He is credited with helping start America's fitness revolution, popularizing the sport of running and demonstrating the health benefits of regular jogging. He died of a heart attack while jogging at 52 years of age. His genetic predisposition for heart problems and other previous lifestyle factors may have caused his heart attack. Born in New York City, Fixx was a graduate of Trinity School in New York and Oberlin College in Ohio. His
Promoter activity Promoter activity Promoter activity is a term that encompasses several meanings around the process of gene expression from regulatory sequences —promoters and enhancers. Gene expression has been commonly characterized as a measure of how much, how fast, when and where this process happens. Promoters and enhancers are required for controlling where and when a specific genes is transcribed. Traditionally the measure of gene products (i.e. mRNA, proteins, etc.) has been the major approach of measure promoter activity. However, this method confront with two issues: the stochastic nature of the gene expression and the lack of mechanistic interpretation of the thermodynamical