The Nutty Professor (1996 film) spawned a sequel, "", which was released in 2000. The film was re-released on Blu-ray combo pack on March 6, 2012, to celebrate the 100th anniversary of Universal Studios. At Wellman College, thousands of hamsters overrun the campus after being accidentally released by Sherman Klump, a morbidly obese but very kind-hearted professor. Meanwhile, Sherman has created an experimental formula that reconstructs the DNA of an obese person in a way that allows them to lose weight more easily. After his lecture, Sherman meets and instantly falls in love with Carla Purty, a chemistry graduate who is a big fan of
Nutty Professor II: The Klumps out in the same crass manner Buddy does. Sherman tries proposing to Denise, but then Buddy kicks in and makes it a perverted sex request, causing Denise to become mortified against him. Determined to be rid of Buddy permanently, and despite Jason warning him of potentially catastrophic consequences for his health, Sherman uses Denise's methodology to isolate and remove the gene in Sherman's DNA where Buddy has manifested and extracts it from inside his body. However, he does not dispose of the genetic material and as a result, Buddy becomes a sentient being when a hair from a Basset Hound