The Nutty Professor (character) recently fallen in love with grad student and chemistry teacher Carla Purty (Jada Pinkett Smith), Klump uses his latest discovery, a weight-loss serum that rewrites the subject's genes, to lose weight in order to spend time with her. Unfortunately, this serum creates the confident but mean-spirited individual known as Buddy Love, due to the testosterone imbalance caused by the transformation causing Buddy to manifest as an independent personality. When Klump's student and assistant Jason learns what has happened, he realizes that Buddy is gaining increasingly greater freedom from the professor's influence. This encourages Klump to take back control of his
Nutty Professor II: The Klumps out in the same crass manner Buddy does. Sherman tries proposing to Denise, but then Buddy kicks in and makes it a perverted sex request, causing Denise to become mortified against him. Determined to be rid of Buddy permanently, and despite Jason warning him of potentially catastrophic consequences for his health, Sherman uses Denise's methodology to isolate and remove the gene in Sherman's DNA where Buddy has manifested and extracts it from inside his body. However, he does not dispose of the genetic material and as a result, Buddy becomes a sentient being when a hair from a Basset Hound