Cold War tensions and the polio vaccine polio vaccine. By the 1950, Jonas Salk had tested both live, attenuated polio vaccines and formaldehyde killed polio vaccines in monkeys and by 1952, began testing on humans. The killed vaccine was found to be effective, with proper filtration of the biological culture. A problem with this vaccine was the perception that to be adequately protected; a child had to get three Salk shots, properly spaced, and a recommended booster shot once a year, which was expensive. It should be noted however, that Jonas Salk, himself, has stated in interviews that this perception is not at all true. This vaccine
SAV001 a feasible option for an HIV vaccine. Indeed, Jonas Salk developed a therapeutic HIV vaccine in 1987, called Remune now being developed by Immune Response BioPharma, Inc., is based on the killed whole virus approach. Remune vaccine has completed over 25 clinical studies to date and showed a robust mechanism of action restoring white blood cell counts in CD4 & CD8 T cells by reducing viral load and increasing immunity. Also, a group of researchers and professionals in the field of HIV strongly advocates that the killed HIV approach must be taken to fight back the global HIV and AIDS