University of Pittsburgh had begun immunization experiments in monkeys using dead polio virus. Soon, however, Salk began to test inoculations in paralyzed polio patients and by 1953 human trials among the general population were initiated. By the spring of the following year, the largest controlled field trials in medical history were underway, and by 1955 the vaccine developed by Salk and his researchers was declared effective. By 1962, Salk's vaccine had reduced the incidence of polio in the United States by 95 percent. The breakthroughs in immunology and vaccine development at Pitt by Salk and his team are considered one of the most
Salk Hall Roosevelt's Public Works Administration. The 225-bed hospital was originally part of the Medical Center associated with the University and was intended to be used primarily to treat communicable diseases. However, when antibiotics virtually eliminated the need to quarantine patients, the building had become a financial burden on the city. Therefore, in September 1949, work began on remodeling the building, and it temporarily housed Pitt's School of Public Health. In October 1957, the Municipal Hospital was formally acquired from the city for $1.3 million ($ million today) and renamed Jonas Salk Hall. For a time, the upper floors of the building