Compulsory voting papers. Compulsory voting is increasingly resented by citizens in some countries such as Brazil, the largest country where compulsory voting is enforced: at the last presidential election in 2014, some 30 million voters, about 21% of registered voters, did not vote, despite the fact that Brazil has some of the most severe penalties enforced against non voters. A study of a Swiss canton where compulsory voting was enforced found that compulsory voting significantly increased electoral support for leftist policy positions in referenda by up to 20 percentage points. Another study found that the effects of universal turnout in the United
Catalytic triad Catalytic triad A catalytic triad is a set of three coordinated amino acids that can be found in the active site of some enzymes. Catalytic triads are most commonly found in hydrolase and transferase enzymes (e.g. proteases, amidases, esterases, acylases, lipases and β-lactamases). An Acid-Base-Nucleophile triad is a common motif for generating a nucleophilic residue for covalent catalysis. The residues form a charge-relay network to polarise and activate the nucleophile, which attacks the substrate, forming a covalent intermediate which is then hydrolysed to release the product and regenerate free enzyme. The nucleophile is most commonly a serine or cysteine amino