Natural scientific research in Canada Queen's/Hotel Dieu Hospital, Kingston, 1845, U of T/Hospital for Sick Children, Toronto, 1875, UBC/Vancouver General Hospital, 1886, Dalhousie/Victoria General Hospital, Halifax, 1887 and the U of A/ the University of Alberta Hospital, Edmonton, 1906. The Connaught Laboratories in Toronto conducted groundbreaking research in the fifties with respect to the world's first polio vaccine. Working with Dr. Jonas Salk in the US, the laboratories developed a safe inactive vaccine using a new synthetic base, Medium 199. This permitted large volume production through a technique that came to be known as the "Toronto Method", which in turn allowed the mass vaccination campaigns
Jonas Salk Crick, codiscoverer of the structure of the DNA molecule, was a leading professor at the institute until his death in 2004. The institute also served as the basis for Bruno Latour and Steve Woolgar's 1979 book "Laboratory Life: The Construction of Scientific Facts". Beginning in the mid-1980s, Salk also engaged in research to develop a vaccine for another, more recent plague, AIDS. To further this research, he cofounded the Immune Response Corporation with Kevin Kimberlin, to search for a vaccine, and patented Remune, an immune-based therapy. He was unable to secure product liability Insurance. The AIDS vaccine project was discontinued