University of Pittsburgh had begun immunization experiments in monkeys using dead polio virus. Soon, however, Salk began to test inoculations in paralyzed polio patients and by 1953 human trials among the general population were initiated. By the spring of the following year, the largest controlled field trials in medical history were underway, and by 1955 the vaccine developed by Salk and his researchers was declared effective. By 1962, Salk's vaccine had reduced the incidence of polio in the United States by 95 percent. The breakthroughs in immunology and vaccine development at Pitt by Salk and his team are considered one of the most
Remune P < 0.05 & HIV-1 lymphocyte proliferation P < 0.001 both favoring the Remune Group. The International AIDS Vaccine Research (IAVA) issued a report on “Whole Killed AIDS Vaccines” in 1999 reviewing a diverse aspect of the killed virus approach. Remune Remune is the first therapeutic HIV vaccine based on the killed whole virus approach. Remune was initially invented by Jonas Salk in 1987 and is now being developed by Immune Response BioPharma, Inc. (IRBP) Remune is a therapeutic HIV/AIDS vaccine that has completed over 25 clinical studies to date and shows a robust mechanism of action restoring white blood