Marshall Space Flight Center previous Spacelab missions were operated. The advent of the Space Shuttle made possible several major space programs in which MSFC had significant responsibilities. These were the International Space Station, the Hubble Space Telescope, the Chandra X-Ray Observatory, and the Compton Gamma-Ray Observatory. The latter three are part of NASA's series of Great Observatories; this series also includes the Spitzer Space Telescope, but this was not launched by a Space Shuttle and MSFC had no significant role in its development. A manned space station had long been in the plans of visionaries. Wernhar von Braun, in his widely read "Collier's Magazine"
Spitzer Space Telescope environment was poorly suited to an onboard infrared telescope due to contamination from the relatively "dirty" vacuum associated with the orbiters. By September 1983 NASA was considering the "possibility of a long duration [free-flyer] SIRTF mission". "Spitzer" is the only one of the Great Observatories not launched by the Space Shuttle, as was originally intended. However, after the 1986 Challenger disaster, the Centaur LH2–LOX upper stage, which would have been required to place it in its final orbit, was banned from Shuttle use. The mission underwent a series of redesigns during the 1990s, primarily due to budget considerations. This resulted