Model organism anticonvulsant properties of lithium salts, which revolutionized the treatment of bipolar disorder, replacing the previous treatments of lobotomy or electroconvulsive therapy. Modern general anaesthetics, such as halothane and related compounds, were also developed through studies on model organisms, and are necessary for modern, complex surgical operations. In the 1940s, Jonas Salk used rhesus monkey studies to isolate the most virulent forms of the polio virus, which led to his creation of a polio vaccine. The vaccine, which was made publicly available in 1955, reduced the incidence of polio 15-fold in the United States over the following five years. Albert Sabin
Salk Institute for Biological Studies have directly influenced Kahn in his design. Ultimately, the Salk Institute's meaning can be interpreted as transcending function and physical place as a reflection of Western civilization's pursuit of truth through science. In 2014, the Getty Conservation Institute partnered with the Salk Institute to preserve the concrete and teak building which is, due to its coastal location, subject to the punishing rigors of a marine environment. Although the Salk Institute is not a degree-granting institution, it runs a graduate program together with the neighboring UCSD, and all Salk Institute professors receive adjunct appointments in the Division of Biological Sciences at