Ruth Handler Club children's television show, Mattel invested heavily in television advertising. The TV commercials for the Barbie doll paid off and Barbie rocketed Mattel and the Handlers to fame and fortune. Subsequently, they would add a boyfriend for Barbie named Ken, after the Handlers' son, and many other "friends and family" to Barbie's world. Handler was diagnosed with breast cancer in 1970. She had a modified radical mastectomy, which was often used at the time to combat the disease, and because of difficulties in finding a good breast prosthesis, she decided to make her own. Handler went on to found a
Chelsea Handler entertainment anchor, Adrianna Costa. In April 2006, Handler began hosting "The Chelsea Handler Show" on E!, which lasted two seasons. In 2007, Handler performed with Comedy Central's Hour Stand-Up Comedy Tour across the United States. Her stand-up comedy has also been televised on VH1's "Love Lounge", Comedy Central's "Premium Blend", and HBO's broadcast of the "Aspen Comedy Festival". She was a guest on "Red Eye w/ Greg Gutfeld" and "The View", and she co-hosted "The View" on August 2, 2007, and September 5, 2008. On August 18, 2010, it was announced that Handler would be the host of the 2010