Marshall Space Flight Center previous Spacelab missions were operated. The advent of the Space Shuttle made possible several major space programs in which MSFC had significant responsibilities. These were the International Space Station, the Hubble Space Telescope, the Chandra X-Ray Observatory, and the Compton Gamma-Ray Observatory. The latter three are part of NASA's series of Great Observatories; this series also includes the Spitzer Space Telescope, but this was not launched by a Space Shuttle and MSFC had no significant role in its development. A manned space station had long been in the plans of visionaries. Wernhar von Braun, in his widely read "Collier's Magazine"
Space Shuttle program and were formally initiated in 1983 by President Ronald Reagan, but the ISS suffered from long delays, design changes and cost over-runs and forced the service life of the Space Shuttle to be extended several times until 2011 when it was finally retired—serving twice as long than it was originally designed to do. In 2004, according to President George W. Bush's Vision for Space Exploration, use of the Space Shuttle was to be focused almost exclusively on completing assembly of the ISS, which was far behind schedule at that point. The first experimental orbiter "Enterprise" was a high-altitude glider, launched