Hilary Koprowski he is chair of the department of radiation oncology at Christiana Hospital in Delaware. While at Lederle Laboratories, Koprowski created the world's first polio vaccine, based on an orally administered attenuated polio virus. In researching a potential polio vaccine, he had focused on live viruses that were attenuated (rendered non-virulent) rather than on killed viruses (the latter became the basis for the injected vaccine subsequently developed by Jonas Salk). Koprowski viewed the live vaccine as more powerful, since it entered the intestinal tract directly and could provide lifelong immunity, whereas the Salk vaccine required booster shots. Also, administering a vaccine
The Immune Response Corporation The Immune Response Corporation The Immune Response Corporation (IRC), founded by Jonas Salk and Kevin Kimberlin and based in Carlsbad, California, pioneered immunotherapeutic products. Francis Crick once said about Salk, “Few have made one discovery that has benefited humanity so greatly. Jonas was a man who, right to his last day, was actively in pursuit of another.” That pursuit was The Immune Response Corporation. Kimberlin “asked Salk to become lead scientific advisor for a new biotech company specializing in ‘anti-idiotypes,’ a novel vaccine technology.” Salk called the proposal “liberating.” The management team included CEO Jim Glavin, former CEO of Genetic