The Nutty Professor (1996 film) spawned a sequel, "", which was released in 2000. The film was re-released on Blu-ray combo pack on March 6, 2012, to celebrate the 100th anniversary of Universal Studios. At Wellman College, thousands of hamsters overrun the campus after being accidentally released by Sherman Klump, a morbidly obese but very kind-hearted professor. Meanwhile, Sherman has created an experimental formula that reconstructs the DNA of an obese person in a way that allows them to lose weight more easily. After his lecture, Sherman meets and instantly falls in love with Carla Purty, a chemistry graduate who is a big fan of
The Nutty Professor (character) Denise (Janet Jackson). In an attempt to eliminate this, Klump uses a risky experiment to extract Buddy's DNA from his system, but his plan backfires and results in Buddy manifesting as an independent entity (albeit with some dog-like traits as his genetic make-up filled in the gaps with samples of canine DNA). Klump proposes to Denise, who happily accepts, but Klump gradually begins to lose his intelligence due to the damage his brain cells have sustained as a result of Buddy being extracted from his system. Eventually, he is able to reabsorb Buddy by using a powerful version of his