Polonium in the Earth's crust are not harmful. Polonium has been found in tobacco smoke from tobacco leaves grown with phosphate fertilizers. Because it is present in small concentrations, isolation of polonium from natural sources is a tedious process. The largest batch of the element ever extracted, performed in the first half of the 20th century, contained only (9 mg) of polonium-210 and was obtained by processing 37 tonnes of residues from radium production. Polonium is now usually obtained by irradiating bismuth with high-energy neutrons or protons. In 1934, an experiment showed that when natural Bi is bombarded with neutrons, Bi
Manhattan Project radioactive polonium was directed by Charles Allen Thomas of the Monsanto Company and became known as the Dayton Project. Testing required up to 500 curies per month of polonium, which Monsanto was able to deliver. The whole assembly was encased in a duralumin bomb casing to protect it from bullets and flak. The ultimate task of the metallurgists was to determine how to cast plutonium into a sphere. The difficulties became apparent when attempts to measure the density of plutonium gave inconsistent results. At first contamination was believed to be the cause, but it was soon determined that there were