Triple test Triple test The triple test, also called triple screen, the Kettering test or the Bart's test, is an investigation performed during pregnancy in the second trimester to classify a patient as either high-risk or low-risk for chromosomal abnormalities (and neural tube defects). The term "multiple-marker screening test" is sometimes used instead. This term can encompass the "double test" and "quadruple test" (described below). The Triple screen measures serum levels of AFP, estriol, and beta-hCG, with a 70% sensitivity and 5% false-positive rate. It is complemented in some regions of the United States, as the "Quad screen" (adding inhibin A to
Quadruple-precision floating-point format implement nearly quadruple precision using "pairs" of double-precision values is sometimes called double-double arithmetic. Using pairs of IEEE double-precision values with 53-bit significands, double-double arithmetic can represent operations with at least a 2×53=106-bit significand (actually 107 bits except for some of the largest values, due to the limited exponent range), only slightly less precise than the 113-bit significand of IEEE binary128 quadruple precision. The range of a double-double remains essentially the same as the double-precision format because the exponent has still 11 bits, significantly lower than the 15-bit exponent of IEEE quadruple precision (a range of for double-double versus for