Banting Research Foundation endowment. A large bequest in 1948 from the estate of Kate E Taylor of Toronto added to the endowment. From its inception, the intent was to create a fund for researchers with "good ideas but no money", as was the situation for Banting when he approached JJR Macleod in 1921 with a request for facilities and resources to pursue his ideas about insulin. The Foundation continues that tradition by making grant funds available only to investigators whose research funding is limited. The Foundation was the first and virtually the only organization funding medical research in Canada until 1938 when the
Highest and best use Since their use predates these regulations, they are "grandfathered in". However, some such uses may not be reproduced if the legally nonconforming improvement is destroyed or damaged beyond a certain point. "Legally permissible" can be a tricky conceptual test, because even uses that are currently not permitted may be considered. This happens when there is a reasonable prospect (at least 50%) that the regulation, zoning, deed restriction, etc. can be changed to permit the proposed use. Any potential use must be physically possible given the size, shape, topography, and other characteristics of the site. For example, a single story warehouse