Tangier Protocol Tangier Protocol The Tangier Protocol (formally the Convention regarding the Organisation of the Statute of the Tangier Zone) was an agreement signed between France, Spain and the United Kingdom by which the city of Tangier in Morocco became the Tangier International Zone. The protocol was signed in Paris on 18 December 1923 and entered into force with ratification on 14 May 1924. Starting from 1929, Spain assumed the policing of the city. An international legislative body was created to govern the city. Spain occupied Tangier from 1940 to 1945, taking advantage of France's occupation by Germany in 1940. The status
Tangier disease enlarged. Affected people often develop premature atherosclerosis, which is characterized by fatty deposits and scar-like tissue lining the arteries. Other signs of this condition may include an enlarged spleen (splenomegaly), an enlarged liver (hepatomegaly), clouding of the cornea, and early-onset cardiovascular disease. Tangier disease is a rare disorder with approximately 50 cases identified worldwide. This disorder was originally discovered on Tangier Island off the coast of Virginia, but has now been identified in people from many different countries. There are drugs that can increase serum HDL such as niacin or gemfibrozil. While these drugs are useful for patients with hyperlipidemia,