Banting Research Foundation endowment. A large bequest in 1948 from the estate of Kate E Taylor of Toronto added to the endowment. From its inception, the intent was to create a fund for researchers with "good ideas but no money", as was the situation for Banting when he approached JJR Macleod in 1921 with a request for facilities and resources to pursue his ideas about insulin. The Foundation continues that tradition by making grant funds available only to investigators whose research funding is limited. The Foundation was the first and virtually the only organization funding medical research in Canada until 1938 when the
Frederick Banting Children, and the Toronto Western Hospital. At the Banting and Best Institute, he focused his research on silicosis, cancer, and the mechanisms of drowning. In 1938, Banting's interest in aviation medicine resulted in his participation with the Royal Canadian Air Force (RCAF) in research concerning the physiological problems encountered by pilots operating high-altitude combat aircraft. Banting headed the RCAF's Number 1 Clinical Investigation Unit (CIU), which was housed in a secret facility on the grounds of the former Eglinton Hunt Club in Toronto. During the Second World War he investigated the problems of aviators, such as "blackout" (syncope). He also