Professor Marston and the Wonder Women upon a lingerie shop in New York City run by Charles Guyette, who introduces him to fetish art themed comics and photos. The art captures William's imagination as a demonstration of his DISC theory. Elizabeth initially disapproves of the art, but she relents during a presentation wherein Olive tries out an outfit that later would be the prototype for Wonder Woman's costume. After finding limited work as a writer, Marston comes up with the idea of creating a female Amazonian super-heroine for a comic book. The comic would feature his ideas on DISC theory, drawing inspiration from the Marstons' work
Professor Marston and the Wonder Women praised Robinson's direction and the performances of its stars. The story is told in flashbacks set during a 1945 testimony that William Moulton Marston gives to representatives of the Child Study Association of America. In the year 1928, William and his wife Elizabeth teach and work on their research at the associated Harvard and Radcliffe Colleges. One day, William hires one of his students, Olive Byrne (daughter of Ethel Byrne and niece of Margaret Sanger – two famous suffragists and feminists of the 20th century) as a research assistant. Olive aids in the Marstons' work in inventing the lie detector