Frederick Banting in the blood which was then excreted in urine. Attempts to extract insulin from ground-up pancreas cells were unsuccessful, likely because of the destruction of the insulin by the proteolysis enzyme of the pancreas. The challenge was to find a way to extract insulin from the pancreas prior to its being destroyed. Moses Barron published an article in 1920 which described experimental closure of the pancreatic duct by ligature; this further influenced Banting's thinking. The procedure caused deterioration of the cells of the pancreas that secrete trypsin which breaks down insulin, but it left the islets of Langerhans intact. Banting
The Pad and How to Use It The Pad and How to Use It The Pad and How to Use It is a 1966 comedy film directed by Brian G. Hutton. It was based on the one-act play "The Private Ear" by Peter Shaffer. A sensitive man named Bob Handman (Brian Bedford), who lives alone in his apartment, encounters what he believes to be his ideal woman, Doreen (Julie Sommars), at a classical music concert. They arrange to meet at a later date at his pad. Because he is so unwordly he asks his best friend Ted (James Farentino) along to the date as well for moral