Frederick Banting realized that this procedure would destroy the trypsin-secreting cells but not the insulin. Once the trypsin-secreting cells had died, insulin could be extracted from the islets of Langerhans. Banting discussed this approach with J. J. R. Macleod, Professor of Physiology at the University of Toronto. Macleod provided experimental facilities and the assistance of one of his students, Charles Best. Banting and Best, with the assistance of biochemist James Collip, began the production of insulin by this means. As the experiments proceeded, the required quantities could no longer be obtained by performing surgery on living dogs. In November 1921, Banting hit
The Pad and How to Use It The Pad and How to Use It The Pad and How to Use It is a 1966 comedy film directed by Brian G. Hutton. It was based on the one-act play "The Private Ear" by Peter Shaffer. A sensitive man named Bob Handman (Brian Bedford), who lives alone in his apartment, encounters what he believes to be his ideal woman, Doreen (Julie Sommars), at a classical music concert. They arrange to meet at a later date at his pad. Because he is so unwordly he asks his best friend Ted (James Farentino) along to the date as well for moral