English Tangier English Tangier English Tangier refers to the Moroccan city of Tangier during the period of its colonial occupation by the Kingdom of England, which lasted from 1661 to 1684. Tangier had been under Portuguese rule before KingCharlesII acquired the city as part of the dowry when he married the Portuguese infanta Catherine. The marriage treaty was an extensive renewal of the Anglo-Portuguese Alliance; it was opposed by Spain (at war with Portugal) but clandestinely supported by France. England garrisoned and fortified the city against hostile (but disunited) Moroccan forces. When Morocco was later united under the Alaouites, the cost of
Tangier disease enlarged. Affected people often develop premature atherosclerosis, which is characterized by fatty deposits and scar-like tissue lining the arteries. Other signs of this condition may include an enlarged spleen (splenomegaly), an enlarged liver (hepatomegaly), clouding of the cornea, and early-onset cardiovascular disease. Tangier disease is a rare disorder with approximately 50 cases identified worldwide. This disorder was originally discovered on Tangier Island off the coast of Virginia, but has now been identified in people from many different countries. There are drugs that can increase serum HDL such as niacin or gemfibrozil. While these drugs are useful for patients with hyperlipidemia,