Banting Research Foundation endowment. A large bequest in 1948 from the estate of Kate E Taylor of Toronto added to the endowment. From its inception, the intent was to create a fund for researchers with "good ideas but no money", as was the situation for Banting when he approached JJR Macleod in 1921 with a request for facilities and resources to pursue his ideas about insulin. The Foundation continues that tradition by making grant funds available only to investigators whose research funding is limited. The Foundation was the first and virtually the only organization funding medical research in Canada until 1938 when the
Highest and best use a series of tests. The exact definition of highest and best use varies, but generally the use must be the following: Only those uses that are, or may be, legally permitted are potential highest and best uses. This may exclude uses that are not, and unlikely to become, permitted by zoning, land use planning, uses forbidden by government regulations, and uses prohibited by deed restrictions or covenants. Properties with a use that predates existing zoning or other property regulations may be "legally nonconforming". Such "grandfathered uses" are generally legal even though they do not meet current zoning or other regulations.