Thomas Wolfe of an immense exuberance, organic in its form, kinetic, and drenched with the love of life... I rejoice over Mr. Wolfe." Both in his 1930 Nobel Prize for Literature acceptance speech and original press conference announcement, Sinclair Lewis, the first American to win the Nobel Prize for literature, said of Wolfe, "He may have a chance to be the greatest American writer... In fact I don't see why he should not be one of the greatest world writers." Upon publication of his second novel, "Of Time and the River", most reviewers and the public remained supportive, though some critics found
Nobel Prize in Physiology or Medicine award. The front side of the medal displays the same profile of Alfred Nobel depicted on the medals for Physics, Chemistry, and Literature. The reverse side is unique to this medal. The most recent Nobel prize was announced by Karolinska Institute on 1 October 2018, and has been awarded to American James P. Allison and Japanese Tasuku Honjo – for their discovery of cancer therapy by inhibition of negative immune regulation. As of 2015, 106 Nobel Prizes in Physiology or Medicine have been awarded to 198 men and 12 women. The first one was awarded in 1901 to the German