Siege of Khartoum support of the Mahdi, and cut the Egyptian traffic on the Nile and the telegraph to Cairo. Communications were not entirely cut, as runners could still get through, but the siege had begun and Khartoum could only rely on its own food stores, which could last five or six months. On 16 March an abortive sortie from Khartoum was launched, which led to the death of 200 Egyptian troops as the combined forces besieging Khartoum grew to over 30,000 men. Through the months of April, May, June, and July, Gordon and the garrison dealt with being cut off as food
HMS Khartoum (F45) screening and patrol duties. "Khartoum" and "Kandahar" detached with other K-class destroyers and for surveillance of Italian warship movements from Massawa on the Red Sea. In June 1940, "Khartoum" deployed in the Red Sea with sloops of the East Indies Squadron and her other sister destroyers and prepared for war service in defense of Red Sea shipping. On 10 June, after the outbreak of war, she deployed for patrol and convoy defense based at Aden. On 21 June she carried out an attack on , a , which was unsuccessful. Then on 23 June she was deployed with "Kandahar", "Kingston"