Polonium the Curies while they were investigating the cause of pitchblende radioactivity. Pitchblende, after removal of the radioactive elements uranium and thorium, was more radioactive than the uranium and thorium combined. This spurred the Curies to search for additional radioactive elements. They first separated out polonium from pitchblende in July 1898, and five months later, also isolated radium. German scientist Willy Marckwald successfully isolated 3 milligrams of polonium in 1902, though at the time he believed it was a new element, which he dubbed "radio-tellurium", and it was not until 1905 that it was demonstrated to be the same as polonium.
Polonium dioxide reaction of polonium dioxide with potassium hydroxide or potassium nitrate in air gives the colourless potassium polonite (KPoO): Polonium dioxide is closely related to the polonite anion (), similar to the relationship between polonium trioxide and the polonate anion (). Polonium dioxide has no uses outside of basic research. All polonium compounds, such as polonium dioxide, are extremely radioactive and thus must be handled in a glove box. The glove box must further be enclosed in another box similar to the glove box, maintained at a slightly lower pressure than the glove box to prevent the radioactive materials from leaking