Charles Best House Charles H. Best was born. Best was educated at the University of Toronto, and in 1921 began a fruitful collaboration with Drs. Frederick Banting and J.J.R. Macleod. On January 11, 1922, Best administered the first dose of insulin to a human subject. Although he was did not formally share in the Nobel Prize in Medicine awarded in 1923 to Banting and Macleod, the latter shared his prize money with Best. Best continued his successful research career with the development of several enzyme-based therapies. He died in 1978. His birthplace was purchased in 1959 by the American Diabetes Association, and transferred
Banting House headed during the Second World War, and an entire gallery filled with artwork done by Banting. Adjacent to the museum is Sir Frederick G. Banting Square, a garden with several information plaques, and three main attractions. Two of the attractions, a full-sized sculpture of Banting writing his life-altering idea down, and the Flame of Hope, were unveiled by Her Majesty Queen Elizabeth The Queen Mother. The Flame of Hope, symbolizing the hope for a final cure for diabetes, was kindled by Her Majesty during her visit. The third attraction is the globe sculpture, which was added more recently in 2010.