Frederick Banting realized that this procedure would destroy the trypsin-secreting cells but not the insulin. Once the trypsin-secreting cells had died, insulin could be extracted from the islets of Langerhans. Banting discussed this approach with J. J. R. Macleod, Professor of Physiology at the University of Toronto. Macleod provided experimental facilities and the assistance of one of his students, Charles Best. Banting and Best, with the assistance of biochemist James Collip, began the production of insulin by this means. As the experiments proceeded, the required quantities could no longer be obtained by performing surgery on living dogs. In November 1921, Banting hit
What I Do the Best Grand on his 1998 debut album "Famous First Words". As listed in liner notes. What I Do the Best What I Do the Best is the fourth studio album by American country music artist John Michael Montgomery. The tracks "Ain't Got Nothin' on Us", "Friends", "How Was I to Know" and "I Miss You a Little" were all released as singles, peaking at #15, #2, #2 and #6, respectively on the Hot Country Songs charts, making this the first album of his career not to produce a #1 hit. The album was certified platinum by the RIAA for one million