Frederick Banting realized that this procedure would destroy the trypsin-secreting cells but not the insulin. Once the trypsin-secreting cells had died, insulin could be extracted from the islets of Langerhans. Banting discussed this approach with J. J. R. Macleod, Professor of Physiology at the University of Toronto. Macleod provided experimental facilities and the assistance of one of his students, Charles Best. Banting and Best, with the assistance of biochemist James Collip, began the production of insulin by this means. As the experiments proceeded, the required quantities could no longer be obtained by performing surgery on living dogs. In November 1921, Banting hit
Banting and Best Centre for Innovation and Entrepreneurship developed in 1921. The Centre, managed by the University of Toronto, set up facilities to foster collaborative work between students, faculty and private enterprise by providing office space, courses and equipment. The centre has also provided jobs for students and recent graduates of the university. Soon after its establishment, the centre began raising money from private investors to fund startup companies. During the first year about $23 million was raised. As of 2016, the centre operates nine business accelerators. Banting and Best Centre for Innovation and Entrepreneurship The Banting and Best Centre for Innovation and Entrepreneurship is an initiative of