Silk silk during the Medieval age. The first center to introduce silk production to Italy was the city of Catanzaro during the 11th century in the region of Calabria. The silk of Catanzaro supplied almost all of Europe and was sold in a large market fair in the port of Reggio Calabria, to Spanish, Venetian, Genovese and Dutch merchants. Catanzaro became the lace capital of the world with a large silkworm breeding facility that produced all the laces and linens used in the Vatican. The city was world-famous for its fine fabrication of silks, velvets, damasks and brocades. Another notable center
Spider silk is believed to be due to antiseptic properties of spider silk and because the silk is rich in vitamin K, which can be effective in clotting blood. Due to the difficulties in extracting and processing substantial amounts of spider silk, the largest known piece of cloth made of spider silk is an textile with a golden tint made in Madagascar in 2009. Eighty-two people worked for four years to collect over one million golden orb spiders and extract silk from them. The silk of "Nephila clavipes" was used in research concerning mammalian neuronal regeneration. Spider silk has been used as