Charles Best House Charles H. Best was born. Best was educated at the University of Toronto, and in 1921 began a fruitful collaboration with Drs. Frederick Banting and J.J.R. Macleod. On January 11, 1922, Best administered the first dose of insulin to a human subject. Although he was did not formally share in the Nobel Prize in Medicine awarded in 1923 to Banting and Macleod, the latter shared his prize money with Best. Best continued his successful research career with the development of several enzyme-based therapies. He died in 1978. His birthplace was purchased in 1959 by the American Diabetes Association, and transferred
William Banting the Public" which contained the particular plan for the diet he followed. It was written as an open letter in the form of a personal testimonial. Banting accounted all of his unsuccessful fasts, diets, spa and exercise regimens in his past. His previously unsuccessful attempts had been on the advice of various medical experts. He then described the dietary change which finally had worked for him, following the advice of another medical expert. "My kind and valued medical adviser is not a doctor for obesity, but stands on the pinnacle of fame in the treatment of another malady, which, as