Allan Rockwell McCann was in charge of the development of a submarine rescue chamber, which bears his name, "The McCann Submarine Rescue Chamber". Additionally he was assigned as Liaison Officer / Engineer when the submarine was converted for use in the under ice attempt to circumnavigate the Arctic Ice cap and voyage to the North Pole. Modifications to the submarine were extensive, and contained innovations of a telescoping conning tower, an ice drill, an incorporated diving bell and an Air Lock, designed by Simon Lake. The submarine was designated "Nautilus" and leased for one dollar to Lake and Danenhower, Inc., of Bridgeport, Connecticut,
Nuclear cap-binding protein complex Nuclear cap-binding protein complex Nuclear cap-binding protein complex is a RNA-binding protein which binds to the 5' cap of pre-mRNA. The cap and nuclear cap-binding protein have many functions in mRNA biogenesis including splicing, 3'-end formation by stabilizing the interaction of the 3'-end processing machinery, nuclear export and protection of the transcripts from nuclease degradation. When RNA is exported to the cytoplasm the nuclear cap-binding protein complex is replaced by cytoplasmic cap binding complex. The nuclear cap-binding complex is a functional heterodimer and composed of Cbc1/Cbc2 in yeast and CBC20/CBC80 in multicellular eukaryotes. Human nuclear cap-binding protein complex shows the