Charles Best House Charles H. Best was born. Best was educated at the University of Toronto, and in 1921 began a fruitful collaboration with Drs. Frederick Banting and J.J.R. Macleod. On January 11, 1922, Best administered the first dose of insulin to a human subject. Although he was did not formally share in the Nobel Prize in Medicine awarded in 1923 to Banting and Macleod, the latter shared his prize money with Best. Best continued his successful research career with the development of several enzyme-based therapies. He died in 1978. His birthplace was purchased in 1959 by the American Diabetes Association, and transferred
Charles Best (medical scientist) ignoring Best and Collip. Banting chose to share half of the prize money with Best. The key contribution by Collip was recognised in the Nobel speech of McLeod, who also gave one-half of his prize money to Collip. Best succeeded Macleod as professor of physiology at University of Toronto in 1929. During World War II he was influential in establishing a Canadian program for securing and using dried human blood serum. In his later years, he was an adviser to the Medical Research Committee of the United Nations World Health Organization. Best was elected a foreign member of the Royal