Triple test Triple test The triple test, also called triple screen, the Kettering test or the Bart's test, is an investigation performed during pregnancy in the second trimester to classify a patient as either high-risk or low-risk for chromosomal abnormalities (and neural tube defects). The term "multiple-marker screening test" is sometimes used instead. This term can encompass the "double test" and "quadruple test" (described below). The Triple screen measures serum levels of AFP, estriol, and beta-hCG, with a 70% sensitivity and 5% false-positive rate. It is complemented in some regions of the United States, as the "Quad screen" (adding inhibin A to
Quadruple-precision floating-point format the double-double technique above, although that technique does not implement IEEE quadruple precision), since direct hardware support for quadruple precision is, as of 2016, less common (see "Hardware support" below). One can use general arbitrary-precision arithmetic libraries to obtain quadruple (or higher) precision, but specialized quadruple-precision implementations may achieve higher performance. A separate question is the extent to which quadruple-precision types are directly incorporated into computer programming languages. Quadruple precision is specified in Fortran by the codice_2 (module codice_3 from Fortran 2008 must be used, the constant codice_4 is equal to 16 on most processors), or as codice_5, or in