Frederick Banting in the blood which was then excreted in urine. Attempts to extract insulin from ground-up pancreas cells were unsuccessful, likely because of the destruction of the insulin by the proteolysis enzyme of the pancreas. The challenge was to find a way to extract insulin from the pancreas prior to its being destroyed. Moses Barron published an article in 1920 which described experimental closure of the pancreatic duct by ligature; this further influenced Banting's thinking. The procedure caused deterioration of the cells of the pancreas that secrete trypsin which breaks down insulin, but it left the islets of Langerhans intact. Banting
Kolej MARA Banting Kolej MARA Banting Kolej MARA Banting (; abbreviated KMB or MCB; formerly known as "MRSM Banting") is one of the four pre-university colleges operated by MARA. The school is state funded and headed by a director. It is a top-ranked IB world school, scoring above the international average in candidates with 45 IB points and candidates obtaining higher than 42 IB points. MCB is an International Baccalaureate World School since October 1990. Its history began in 1985 when the GCE A-Level programme was introduced in MARA Junior Science College Seremban (MRSM Seremban, now known as Kolej MARA Seremban). To diversify