In vivo, in separate experiments using murine models of CML, dasatinib prevented the progression of chronic CML to blast phase and prolonged the survival of mice bearing patient-derived CML cell lines grown at various sites, including the central nervous system.
I separate eksperimenter med murine modeller af CML, forebyggede dasatinib in- vivo progression af kronisk CML til blastfase og forlængede overlevelsen hos mus med patient- deriverede CML - cellelinier placeret forskellige steder, inklusive centralnervesystemet.