This effect was not confirmed in vivo in the Mouse Micronucleus Test in the rat Unscheduled DNA Synthesis (UDS) test.
Denne mutagene effekt kan muligvis tilskrives rotigotins clastogene effekt, men denne effekt bekræftedes ikke in vivo i musemikronukleustesten eller i UDS- testen (Unscheduled DNA Synthesis) med rotter.