Preclinical evaluations to support the administration of hydrochlorothiazide in humans included in vitro genotoxicity assays and reproductive toxicity and carcinogenicity studies in rodents.
Prækliniske evalueringer, der støtter administrationen af hydrochlorthiazid til mennesker, omfattede in vitro - genotoksicitetsanalyser og reproduktionstoksicitets - og carcinogenicitetsstudier af gnavere.