The Global Project on Anti-Tuberculosis Drug Resistance Surveillance has collected information on prevalence, patterns, and trends of drug resistance since 1994, focusing on resistance to first-line drugs and contributing much to our understanding of MDR-TB.  But surveillance for XDR-TB has been more limited, as drug susceptibility testing for second-line drugs is not well-standardized and for some drugs is poorly reproducible, while few countries perform such testing within the context of their national TB programs.
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