Here is a breakdown of the source code representation of a Java class. A class can be broken down into two things: 1  The first piece is a class-header which consists of the keyword  class  and the name you give to the class. 2  Names in programming languages are also known as identifiers. 3  The second piece is the body.
The long isoform consists of 1162 amino acids and is the only Leptin receptor isoform with clearly demonstrated signaling capability [1]. Leptin signaling occurs typically through the JAK/STAT pathway. Janus kinase 2 (JAK2) activation leads to tyrosine phosphorylation of Leptin receptor. Phosphorylated Tyr1138 of Leptin receptor serves as a binding site for STAT proteins.
Keryx is developing KRX-0401 (perifosine), a novel, potentially first-in-class, oral anti-cancer agent that inhibits Akt activation in the phosphoinositide 3-kinase (PI3K) pathway, and also affects a number of other key signal transduction pathways, including the JNK pathway, all of which are pathways associated with programmed cell death, cell ...