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On either 10 or 11 June 323 BC, Alexander died in the palace of Nebuchadnezzar II, in Babylon, at age 32. There are two different versions of Alexander's death and details of the death differ slightly in each.
Alexander died young, at the age of 33, so a Westward push, if he was planning one, never happened. However, some years after the death of Alexander the Great, his second cousin King Pyrrhus of Epirus, another brilliant general, did invade Italy and clashed with the Romans. His army, which included elephants, did manage some victories against the Romans, but at the cost of many of his finest troops, whereas the Romans were resilient and kept coming back for more rounds.