Noun[edit] legacy â(plural legacies) ( 1 law) Money or property bequeathed to someone in a will.  Something inherited from a predecessor; a heritage.
Seropositive Rheumatoid Arthritis. Seropositive rheumatoid arthritis is nothing but the same rheumatoid arthritis, the blood test done for which shows presence of rheumatoid factor, or RF, in it.here is no definite cure for this disease and the treatment is mainly based on symptom relief. In seropositive rheumatoid arthritis, it can only be said that the patient definitely has the disease, which is not certain with the seronegative counterpart.
The pathophysiology of rheumatoid arthritis is mediated by an inter-related network of cytokines, proteolytic enzymes and prostanoids. IL-1, TNF-alpha, etc. are proinflammatory cytokines and are the central mediators in the disease.nterleukin (IL)-1 is highly responsible for the signs and symptoms of rheumatoid arthritis. First it mediates inflammation by recruiting neutrophils into the joint, activating macrophages, and stimulating T-and B-cell proliferation and differentiation.