Itai-itai disease (ã¤ã¿ã¤ã¤ã¿ã¤ç, itai-itai byÅ? ), (literally: ouch-ouch disease) was the first documented case of mass cadmium poisoning in the world in Toyama Prefecture, Japan in 1950. The cadmium poisoning caused softening of the bones and kidney failures.
Weighted grades are number or letter grades that are assigned a numerical advantage when calculating a grade point average, or GPA.
Take AP/IB classes and get good grades. I think GPA (unweighted) is looked at first and then the HPA (what we called the weighted GPA) is looked at. To know the rigor of your classes, schools look at your transcript. HS can use whatever weighted GPA system they want to.