prodrug A substance which, after metabolic action in the body, is coverted to an active drug. prodrug drug modified by biotransformation (i.e. metabolic processes) to achieve desired pharmacological action proÂ·drug (prÅ'drÅ­g) A class of drugs, the pharmacologic action of which results from conversion by metabolic processes within the body.
verb (used without object), sagged, sagging. 1. to sink or bend downward by weight or pressure, especially in the middle: The roof sags. 2. to hang down unevenly; droop: Her skirt was sagging.
If the sagging appears in the plane of the roof, that is, up and down between the ridge and the eave and from side to side, the sagging is probably due to deflection and creep of the rafters themselves (Figures 8 and 9).f the sagging appears in the plane of the roof, that is, up and down between the ridge and the eave and from side to side, the sagging is probably due to deflection and creep of the rafters themselves (Figures 8 and 9).