The symptoms vary enormously between people with myasthenia gravis: 1  The muscles around the eyes are most commonly affected first, as these are constantly used and can quickly tire. 2  Muscles around the face and throat are also often affected. 3  Weakness in the arms, hands, fingers, legs and neck may develop.
In its most general form, a nipple is a structure from which a fluid emanates. More specifically, it is the projection on the breasts or udder of a mammal by which, in females, breast milk is delivered to a mother's young.
The nipple is usually located at the rim end of the spoke but on some wheels is at the hub end to move its weight closer to the axis of the wheel, reducing the moment of inertia. Until recently there were only two types of nipples: brass and aluminum (often referred to as alloy).