If your bottle is not clean, or is questionable, or hasn't been used since last year, clean it first. 1  Empty the bottle. 2  Refill halfway with tap water. 3  Add a small amount of bleach (1 tablespoon)  Add a small amount of laundry detergent (1 1  teaspoon) Cap and shake vigorously. [Be careful of the cap: drips will bleach your clothes]
The blood of a person suffering from hemophilia doesnât coagulate easily or quickly. This genetic disorder was first discovered in 1803 by Philadelphian physician, Dr. John Conrad Otto. He verified that the disorder was hereditary and it affected males more as compared to females.
Hemophilia is an inherited disease. Hemophilia is caused by a defect in one of the genes that determines how the body makes blood clotting factors 8 and 9. These genes are located on the X chromosomes, which determine whether a baby is a boy or girl.8 and F9 Genes. Mutations in the F8 or F9 genes cause hemophilia. Mutations in the F8 gene cause hemophilia A, while hemophilia B is caused by mutations in the F9 gene. The proteins made by these genes play a critical role in the process of blood clotting.