Itai-itai disease (ã¤ã¿ã¤ã¤ã¿ã¤ç, itai-itai byÅ? ), (literally: ouch-ouch disease) was the first documented case of mass cadmium poisoning in the world in Toyama Prefecture, Japan in 1950. The cadmium poisoning caused softening of the bones and kidney failures.
Weighted grades are number or letter grades that are assigned a numerical advantage when calculating a grade point average, or GPA.
For example, if your teacher tells you that the assignments are worth 30 percent, the tests are worth 25 percent and the final exam is worth 45 percent, these are the weights â this is how much each of these categories contribute to your overall grade. The weighted average is 78.25, which is your final grade. About the Author.