Forces That Drive Tertiary Structure. Most proteins fold into their tertiary structure in an aqueous environment-a cell is, after all, 60% water. The chemical properties of the various R-groups (sidechains) of the amino acids within the protein chain will influence the way that the protein folds in its environment.
This cold sensation will last approximately three to five minutes until a burning sensation appears. The burning sensation will fade into an ache, followed by numbness. Beware that once numbing occurs, remove and discontinue the ice. Continued application following numbing may result in tissue damage.
Place ICE on your ankle for 10-20 minutes every 1.5 to 2 hours for the first 2 to 3 days or until the pain goes away. COMPRESS the area by having a trainer or physiotherapist use an ankle wrap with a tensor. This helps decrease swelling and internal bleeding.