Forces That Drive Tertiary Structure. Most proteins fold into their tertiary structure in an aqueous environment-a cell is, after all, 60% water. The chemical properties of the various R-groups (sidechains) of the amino acids within the protein chain will influence the way that the protein folds in its environment.
This cold sensation will last approximately three to five minutes until a burning sensation appears. The burning sensation will fade into an ache, followed by numbness. Beware that once numbing occurs, remove and discontinue the ice. Continued application following numbing may result in tissue damage.
You can ice beyond 48 hours, until swelling, tenderness or inflammation are gone. Ice massage: Freeze water in a Dixie cup, peel back the top, and massage the tender area until itâs numb. (Best for targeted icing after injury or for areas too awkward for ice packs, like the elbow or heel).