Itai-itai disease (ã¤ã¿ã¤ã¤ã¿ã¤ç, itai-itai byÅ? ), (literally: ouch-ouch disease) was the first documented case of mass cadmium poisoning in the world in Toyama Prefecture, Japan in 1950. The cadmium poisoning caused softening of the bones and kidney failures.
Weighted grades are number or letter grades that are assigned a numerical advantage when calculating a grade point average, or GPA.
Coursework/GPA. Your weighted GPA in high school tells colleges a lot about your ability to take on academic challenges. In this article, Iâll go through a basic description of what a weighted GPA is, why it matters for you, and how you can calculate your own weighted GPA if your school uses this type of scale.