Itai-itai disease (ã¤ã¿ã¤ã¤ã¿ã¤ç, itai-itai byÅ? ), (literally: ouch-ouch disease) was the first documented case of mass cadmium poisoning in the world in Toyama Prefecture, Japan in 1950. The cadmium poisoning caused softening of the bones and kidney failures.
Weighted grades are number or letter grades that are assigned a numerical advantage when calculating a grade point average, or GPA.
Bum....my son's school has weighted and unweighted numbers reported on his transcript, and these schools know what to look for. Also, what most schools look at is what is called the Carnegie GPA, which is the unweighted GPA in core courses. For example, my son is in a special arts magnet program and has been throughout high school.