Itai-itai disease (ã¤ã¿ã¤ã¤ã¿ã¤ç, itai-itai byÅ? ), (literally: ouch-ouch disease) was the first documented case of mass cadmium poisoning in the world in Toyama Prefecture, Japan in 1950. The cadmium poisoning caused softening of the bones and kidney failures.
Weighted grades are number or letter grades that are assigned a numerical advantage when calculating a grade point average, or GPA.
Students receive grades at the end of a unit in any study course, and the grade point average or the GPA is the average of these grades obtained in a term (term GPA) or over the entire course (GPA). There are two different types of GPA called weighted and unweighted GPA.