Pre-symptomatic late infantile MLD patients, as well as those with juvenile or adult MLD that are either presymptomatic or displaying mild symptoms, can consider bone marrow transplantation (including stem cell transplantation), which may slow down progression of the disease in the central nervous system.
Dose-dependent effects of the indicated TBEV inhibitors on virus titres. PS cells were infected with TBEV at a multiplicity of infection (MOI) of 0.1 and treated with 2â²-C-methylguanosine (A), 2â²-C-methyluridine (B), RO-9187 (C) and (D) 4â²-azidocytidine at the indicated concentrations.
1 A CD4 + T cell that recognizes the displayed antigen is stimulated to release lymphokines. 2  These, in turn, stimulate the B cell to enter the cell cycle. 3  Because of the part they play in stimulating B cells, these CD4 + T cells are called Helper T cells ( Th ). A CD4 + T cell that recognizes the displayed antigen is stimulated to release lymphokines. 2  These, in turn, stimulate the B cell to enter the cell cycle. 3  Because of the part they play in stimulating B cells, these CD4 + T cells are called Helper T cells ( Th ).