' 'M*A*S*H' and the medium,' Gelbart added, 'were made for each other.' For 11 years (10 in the Top 20), the show deftly blended sharp, thoughtful humor wi (moreâ¦)A beloved, multi-Emmy-winning series about Army surgeons cutting up amid the Korean War. 'War is hell.
CHAPTER 24 Plasma Membrane Receptors Cells use about 20 different families of receptor proteins to detect and respond to the myriad of incoming chemical and physical stimuli (Appendix 24-1). Most receptors are plasma membrane proteins that interact with chemical ligands or are stimulated by physical events such as light absorption. A few chemical stimuli, including steroid hormones and the gas nitric oxide, cross the plasma membrane and bind receptors inside the cell. Figure 24-1 sixteen classes of receptors with signal transduction mechanisms.
Water-soluble hormones: -do NOT pass readily through the lipid-rich plasma membrane that surrounds the target cell. -Instead, they bind with receptors on the surface of the target cell. -The receptors are glycoprotein complexes. Process of water-soluble hormones: -The receptors have a binding domain that projects beyond the outside of the plasma membrane and a catalytic domain that projects into the cytoplasm of the cell. -Directly or indirectly, most receptors initiate cellular responses by activating protein kinases, which catalyze the transfer of phosphate groups from ATP to specific proteins.