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Pap screen testing should begin at age 21. Routine screening is recommended every three years for women ages 21 to 65. For women ages 30 to 65 who have a normal Pap test result and negative HPV test, rescreening should be done in five years.
In the United States, Pap smear screening is recommended starting around 21 years of age until the age of 65. Guidelines on frequency vary from every three to five years. If results are abnormal, and depending on the nature of the abnormality, the test may need to be repeated in six to twelve months. Pap smear is performed by opening the vaginal canal with a speculum, then collecting cells at the outer opening of the cervix at the transformation zone (where the outer squamous cervical cells meet the inner glandular endocervical cells).