Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis. There may be associated erythema.
Blood Clots. A blood clot needs to be considered as a cause of calf pain, especially when the calf pain is not the immediate result of an injury. Blood clots can form is the deep veins of the leg, causing a blockage in circulation. This may cause swelling and pain in the calf.
The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. The exact mechanism is unknown, but the cramps are probably caused by muscle fatigue and nerve dysfunction rather than electrolyte or other abnormalities.