Source(s): immigration nationality directorate border immigration uk border agency reference no: https://tinyurl.im/UEZro.
About 99% of mouse genes have a homolog in the human genome, and for 80% of these genes, the best match in the human genome has, in turn, its best match against the orthologous mouse gene in the conserved syntenic interval.
The researchers found that, at a general level, gene regulation and other systems important to mammalian biology have many similarities between mice and humans. Specific DNA sequence differences linked to diseases in humans often have counterparts in the mouse genome. Genes whose expression patterns are related in one species also tend to be similarly related in the other species. These findings validate the importance of using mouse models to study certain human diseases.