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PREPARATIONS: Polymyxin B sulfate/trimethoprim is a sterile eye drop, containing polymyxin B sulfate 10,000 units/ml and trimethoprim sulfate 1 mg/ml, available in 10 ml dispenser bottles. DRUG INTERACTIONS: Drug interactions have not been established for polymyxin B sulfate/trimethoprim combination eye drops.
Polymyxin B sulfate/trimethoprim is effective against gram-positive and gram-negative bacteria such as Staphylococcus aureus and epidermis, Streptococcus pyogenes, Streptococcus faecalis, Streptococcus pneumonia, E. coli, Haemophilus influenzae, Klebsiella pneumoniae, and Pseudomonas aeruginosa.