Sofia first appears with her mother on the way to Enchancia Castle to deliver slippers to King Roland II. When her mother and the King marry, Sofia becomes Enchancia's second Princess and the Royal Family's youngest member. Sofia says good-bye to her friends Ruby and Jade before heading to the castle.
Generally, the recommended starting dosage for treating water retention in children is 2 mg per kilogram per day, up to a maximum of 6 mg per kilogram per day. The dose of LasixÂ® (furosemide) your healthcare provider recommends will vary depending on a number of factors, including:
The protein binding of furosemide was investigated in plasma from 22 old and 11 young subjects by equilibrium dialysis.The unbound fraction of furosemide was 3.16% in plasma from the elderly and 1.71% in plasma from the young.A significant correlation was found between the unbound fraction of furosemide and the plasma concentration of albumin. The average number of binding sites was 3.8 (elderly) and 2.7 (young) 10 â6 mol/g albumin.The average association constant (K) was 4.3 (elderly) and 4.2 (young) 10 5 M â1. significant correlation was found between the unbound fraction of furosemide and the plasma concentration of albumin. The average number of binding sites was 3.8 (elderly) and 2.7 (young) 10 â6 mol/g albumin. The average association constant (K) was 4.3 (elderly) and 4.2 (young) 10 5 M â1.