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Symptoms. Signs and symptoms of appendicitis may include: 1  Sudden pain that begins on the right side of the lower abdomen. 2  Sudden pain that begins around your navel and often shifts to your lower right abdomen. 3  Pain that worsens if you cough, walk or make other jarring movements. 4  Nausea and vomiting.
Rupture, the most serious complication of appendicitis, can occur within 24 hours after the appendix becomes inflamed. This can result in infection of the lining of the abdominal cavity (peritoneum), which has the potential to travel through the blood stream.