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At a basic level, Gluconeogensis is an anabolic process. It involves the creation of a 6 carbon glucose molecule from smaller precursors. The name gluco (glucose) neo (new) genesis (creation) is quite descriptive of what the pathway does. Ana-bolic is greek for upward-throw.
Gluconeogenesis Pathway. Basically Gluconeogenesis is the reversal of Glycolysis which is the process of breaking down of glucose to produce energy. [ 1 ]Glycolysis proceeds to another energy cycle called Citric acid cycle by forming a substance called pyruvate.So, Gluconeogenesis is just the reversal of Glycolysis â starting with pyruvate. This removes the inhibition on the key enzyme of Gluconeogenesis and stimulates it. 2  Thus it acts as a counter hormone to insulin. 3  It causes conversion of pyruvate kinase to its inactive form by phosphorylation thus inhibiting Glycolysis and favoring Gluconeogenesis.