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Pap screen testing should begin at age 21. Routine screening is recommended every three years for women ages 21 to 65. For women ages 30 to 65 who have a normal Pap test result and negative HPV test, rescreening should be done in five years.
How often you have a Pap smear depends on your age and previous Pap smear results. The latest guidelines from ACOG suggest that: Women in their 20's should have a Pap smear every 3 years. Women in their 30's to 65 years of age should undergo screening every 3-5 years.