Product Development and Drug Testing. To predict toxicity, corrosivity, and other safety variables as well as the effectiveness of new products, traditional testing of chemicals, consumer products, medical devices, and new drugs has involved the use of animals.r. Gerhard Zbinden, one of the world's leading toxicologists, once described a standard in vivo test as little more than âa ritual mass execution of animals.â The testing of just one substance alone, be it a potential drug or toxic chemical, can involve using up to 800 animals and cost over $6 million. [1].
Paleness should be distinguished from other causes of prominent white skin 1  : Fair skin is genetically determined skin hue with low concentration of skin pigment (melanin) in the skin.
22q11.2 deletion syndrome is a genetic disorder. In this syndrome, a tiny piece of chromosome 22 is missing. This can cause many medical problems. These problems may range from heart defects and developmental delays to seizures and effects on facial appearance. These might include cleft palate (an opening in the roof of the mouth). In 22q11.2 deletion syndrome, a tiny piece of chromosome 22 is missing from the long arm of chromosome 22, at a location called q11.2.