Product Development and Drug Testing. To predict toxicity, corrosivity, and other safety variables as well as the effectiveness of new products, traditional testing of chemicals, consumer products, medical devices, and new drugs has involved the use of animals.r. Gerhard Zbinden, one of the world's leading toxicologists, once described a standard in vivo test as little more than âa ritual mass execution of animals.â The testing of just one substance alone, be it a potential drug or toxic chemical, can involve using up to 800 animals and cost over $6 million. [1].
Paleness should be distinguished from other causes of prominent white skin 1  : Fair skin is genetically determined skin hue with low concentration of skin pigment (melanin) in the skin.
Variation in genes and skin color. One gene responsible for the production of melanin pigment is SLC24A5. It is found that there are two variations of SLC24A5: 1) One variation is with the amino acid called threonine, which is responsible for the light color of the skin.he pigment that gives color to your skin is melanin. It is also responsible for the color of your eyes. Melanin protects our skin from harmful ultraviolet radiation of the sun by absorbing the rays. More melanin pigment is produced by people with dark skin as compared to light skinned persons.