Forces That Drive Tertiary Structure. Most proteins fold into their tertiary structure in an aqueous environment-a cell is, after all, 60% water. The chemical properties of the various R-groups (sidechains) of the amino acids within the protein chain will influence the way that the protein folds in its environment.
This cold sensation will last approximately three to five minutes until a burning sensation appears. The burning sensation will fade into an ache, followed by numbness. Beware that once numbing occurs, remove and discontinue the ice. Continued application following numbing may result in tissue damage.
However, do not put the ice directly on top of the wound until it is completely healed (at least 14 days). 1  Place ice in a clean plastic bag. 2  Put a single layer of towel between the ice bag and your skin. 3  Check your skin under the ice.  Leave the ice in place for no more than 10 minutes each time you use it.