Itai-itai disease (ã¤ã¿ã¤ã¤ã¿ã¤ç, itai-itai byÅ? ), (literally: ouch-ouch disease) was the first documented case of mass cadmium poisoning in the world in Toyama Prefecture, Japan in 1950. The cadmium poisoning caused softening of the bones and kidney failures.
Weighted grades are number or letter grades that are assigned a numerical advantage when calculating a grade point average, or GPA.
Weighted GPA, Unweighted GPA, Class Rank, and College Admission. Why do high schools give extra weights to honors, Advanced Placement (AP), and International Baccalaureate (IB) courses? Readers of some of my other posts related to GPA have expressed confusion.