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Physiological and pathological changes are main inducing factors of diminished kidney function, which includes trauma, infection, inflammation, immune response, blood circulatory disorder, etc.
Sometimes the kidneys can stop working very suddenly (within two days). 1  This type of kidney failure is called acute kidney injury or acute renal failure. Common causes of acute renal failure include: 2  Heart attack. 3  Illegal drug use and drug abuse. 4  Not enough blood flowing to the kidneys. 5  Urinary tract problems.