A Honor Society of Nursing (STTI) answered. Tethered spinal cord syndrome is a neurological disorder caused by tissue attachments that limit the movement of the spinal cord within the spinal column. These attachments cause an abnormal stretching of the spinal cord.The course of the disorder is progressive. Honor Society of Nursing (STTI) answered. Tethered spinal cord syndrome is a neurological disorder caused by tissue attachments that limit the movement of the spinal cord within the spinal column. These attachments cause an abnormal stretching of the spinal cord. The course of the disorder is progressive.
Translocation Down syndrome: This type accounts for a small percentage of people with Down syndrome (about 3%). 2 This occurs when an extra part or a whole extra chromosome 21 is present, but it is attached or âtrans-locatedâ to a different chromosome rather than being a separate chromosome 21.
The most common translocation in humans involves chromosomes 13 and 14 and is seen in about 0.97 / 1000 newborns. Carriers of Robertsonian translocations are not associated with any phenotypic abnormalities, but there is a risk of unbalanced gametes that lead to miscarriages or abnormal offspring. For example, carriers of Robertsonian translocations involving chromosome 21 have a higher chance of having a child with Down syndrome.