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PREPARATIONS: Polymyxin B sulfate/trimethoprim is a sterile eye drop, containing polymyxin B sulfate 10,000 units/ml and trimethoprim sulfate 1 mg/ml, available in 10 ml dispenser bottles. DRUG INTERACTIONS: Drug interactions have not been established for polymyxin B sulfate/trimethoprim combination eye drops.
It works mainly by increasing the activity of norepinephrine (noradrenaline) on adrenergic receptors. It is most usually marketed as the hydrochloride or sulfate salt. The herb Ephedra sinica, used in traditional Chinese medicine, contains ephedrine and pseudoephedrine as its principal active constituents. The same may be true of other herbal products containing extracts from other Ephedra species.