Sofia first appears with her mother on the way to Enchancia Castle to deliver slippers to King Roland II. When her mother and the King marry, Sofia becomes Enchancia's second Princess and the Royal Family's youngest member. Sofia says good-bye to her friends Ruby and Jade before heading to the castle.
Generally, the recommended starting dosage for treating water retention in children is 2 mg per kilogram per day, up to a maximum of 6 mg per kilogram per day. The dose of LasixÂ® (furosemide) your healthcare provider recommends will vary depending on a number of factors, including:
The onset of action after oral administration is within one hour, and the diuresis lasts about 6-8 hours. The onset of action after injection is five minutes and the duration of diuresis is two hours. The diuretic effect of furosemide can cause depletion of sodium, chloride, body water and other minerals. Therefore, careful medical supervision is necessary during treatment. The FDA approved furosemide in July 1982.