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An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.n average the cost per patient for orphan drugs is six times that of non-orphan drugs, a clear indication of their pricing power.. Partly as a result of the 1983 US Orphan Drug Act, Japan adopted it in 1993 as did the European Union in 2000.
adjective. noun. The definition of orphan is a child or something related to a child who's lost their parents. An example of orphan is a home for children without parents; an orphan home. An orphan is defined as a child whose parents have died. An example of an orphan is a little girl whose mother and father died in a car accident.