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What causes a fistula? After an abscess has been drained, a passage may remain between the anal gland and the skin, resulting in a fistula. If the gland does not heal, there will be persistent drainage through this passage. If the outside opening of the fistula heals first, a recurrent abscess may develop.
Perianal fistula. A perianal fistula is an abnormal connection between the epithilialised surface of the anal canal and the skin. The causes of perianal fistulas: Primary Obstruction of anal gland which leads to stasis and infection with absces and fistula formation (most common cause).