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Pap screen testing should begin at age 21. Routine screening is recommended every three years for women ages 21 to 65. For women ages 30 to 65 who have a normal Pap test result and negative HPV test, rescreening should be done in five years.
One of the following for women aged 21 to 24: 1  Repeat Pap test at 12-month intervals; if two consecutive negative tests, return to routine screening. 2  Reflex HPV test; if HPV-positive, repeat Pap in 12 months; if HPV-negative, return for Pap testing in 3 years.