Itai-itai disease (ã¤ã¿ã¤ã¤ã¿ã¤ç, itai-itai byÅ? ), (literally: ouch-ouch disease) was the first documented case of mass cadmium poisoning in the world in Toyama Prefecture, Japan in 1950. The cadmium poisoning caused softening of the bones and kidney failures.
Weighted grades are number or letter grades that are assigned a numerical advantage when calculating a grade point average, or GPA.
Grades can range from A+ to an F on the 4.0 Scale. For each class, choose a letter grade from the drop-down menu. Step 2 - Add Your Class Credits. Enter the grade and earned credit for each class. For example, if you have earned A for a 4 credit class, then enter 4 in the box next to the âA.â You can add both weighted and unweighted high school classes. Your weighted classes receive extra points on the GPA scale.