Forces That Drive Tertiary Structure. Most proteins fold into their tertiary structure in an aqueous environment-a cell is, after all, 60% water. The chemical properties of the various R-groups (sidechains) of the amino acids within the protein chain will influence the way that the protein folds in its environment.
This cold sensation will last approximately three to five minutes until a burning sensation appears. The burning sensation will fade into an ache, followed by numbness. Beware that once numbing occurs, remove and discontinue the ice. Continued application following numbing may result in tissue damage.
Put ice on your ankle to reduce pain and swelling. Do this for 20 to 30 minutes, every three to four hours, for two to three days or until the pain has gone. After that, ice your ankle once a day until you have no other symptoms. Never put ice directly against the skin, wrap it in a cloth. Compress your ankle.