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âA.C., New York, New YorkThere are a number of substitutes for buttermilk in baking. For each cup of buttermilk, you can use 1 tablespoon of white vinegar or lemon juice plus enough milk to measure 1 cup.
Buttermilk contains less lactose than regular milk and may not cause common lactose intolerance symptoms in some people. Your doctor may recommend a challenge diet to determine whether you should use buttermilk instead of regular milk. If you have adverse reactions, stop drinking buttermilk and call your doctor.