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As with other thyroid-related problems, nodules are more common in women than men and the risk in both sexes increases with age. Most thyroid nodules do not cause any symptoms. However, if they grow large enough, they can cause swelling in the neck and lead to breathing and swallowing difficulties, pain, and goiter.
Graves' disease. The most common cause of hyperthyroidism is an autoimmune condition called Graves' disease. The body's immune system creates an antibody that causes the gland to make an excessive amount of thyroid hormone. Graves' disease runs in families, and usually affects younger women.Thyroiditis.hyroiditis is inflammation of the thyroid. A virus or problem with the immune system causes the gland to swell, leaking thyroid hormone into the bloodstream. There are several types of thyroiditis. 1  Subacute: A sudden, painful form of thyroiditis of unknown cause.