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Injury can also affect the ligaments, cartilage, and bones within the joint. Pain is also a feature of joint inflammation (arthritis, such as rheumatoid arthritis and osteoarthritis) and infection, and extremely rarely it can be a cause of cancer of the joint.Pain within the joint is a common cause of shoulder pain, ankle pain, and knee pain.Joint pain is also referred to as arthralgia.njury can also affect the ligaments, cartilage, and bones within the joint. Pain is also a feature of joint inflammation (arthritis, such as rheumatoid arthritis and osteoarthritis) and infection, and extremely rarely it can be a cause of cancer of the joint.
Painful Joints and Inflamed Joints. Inflammation is a physiological response to injury characterized by four cardinal features â pain, swelling, redness and heat. When a joint is inflamed, it is referred to as arthritis. However, pain in the joints may occur without inflammation and in this case it is simply referred to as arthralgia. However, the term âarthralgiaâ is broad and can still be attributed to pain associated with inflammation.