Source(s): immigration nationality directorate border immigration uk border agency reference no: https://tinyurl.im/UEZro.
About 99% of mouse genes have a homolog in the human genome, and for 80% of these genes, the best match in the human genome has, in turn, its best match against the orthologous mouse gene in the conserved syntenic interval.
For example, the three mouse models depicted on the right in Figure 4 carry different portions of MMU16, and all display some symptoms of DS. Of the three, the most faithful model of DS is the Ts65Dn mouse, which carries 132 genes that are syntenic with human chromosome 21.