Itai-itai disease (ã¤ã¿ã¤ã¤ã¿ã¤ç, itai-itai byÅ? ), (literally: ouch-ouch disease) was the first documented case of mass cadmium poisoning in the world in Toyama Prefecture, Japan in 1950. The cadmium poisoning caused softening of the bones and kidney failures.
Weighted grades are number or letter grades that are assigned a numerical advantage when calculating a grade point average, or GPA.
Replies to: Converting weighted GPA to unweighted. Anything above 4.0 is probably a weighted GPA, anything above 4.5 is definitely a weighted GPA. Add up all of the grades then divide by the number of classes you have taken. No extra points for honors or AP classes.