The following books and articles on Hawk's Nest Tunnel Disaster can be found at the West Virginia Archives and History Library. BOOKS. Cherniack, Martin. The Hawk's Nest Incident; America's Worst Industrial Disaster. New Haven, Connecticut, Yale University Press, 1986. 363.179 C521.
There are three different types of myofilaments: thick, thin, and elastic filaments. Thick filaments consist primarily of the protein myosin. Each thick filament is approximately 15 nm in diameter, and each is made of several hundred molecules of myosin. A myosin molecule is shaped like a golf club, with a tail formed of two intertwined chains and a double globular head projecting from it at an angle.
Actin -forms the bulk of the thin filaments. a. Myosin binding sites-on each actin molecule. Myosin cross bridges can attach to these myosin binding sites. b. 2 Regulatory Proteins in the Thin Filaments 1) Tropomyosin -covers the myosin binding sites on actin molecules when muscles are relaxed. This protein blocks the attachment of myosin heads to actin. 2) Troponin -holds the tropomyosin in place in relaxed muscle tissue.