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According to The Pill Book Guide to Medication For Your Dog and Cat (Kate A.W. Roby, VMD, et al, 1998), cats are started off at 1 mg of prednisone per pound that the cat weighs. This is given one or two times a day. When the cat seems better, one dose is given every other day until the cat is cured.
Prednisone is indicated for patients with widespread inflammation who are very uncomfortable. Wet compresses are still used even if the patient requires prednisone. A typical dose of prednisone for the average size adult is prednisone 20 mg twice a day for 7-10 days followed by 20 mg a day in the morning for 3 days. That program should be adequate to treat most cases of poison ivy. Patients treated with steroid dose packs in which the dosage of prednisone or a similar oral steroid is rapidly decreased over several days will probably respond. However others may not improve or even get worse with this low dose rapid taper program.