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Hypertrichosis can be congenital or acquired. The acquired condition is usually caused by an illness or drugs. Illnesses that might cause this condition are hypothyroidism, malnutrition, AIDS, dermatomyositis (a connective tissue disease), and porphyria cutanea tarda (a condition involving enzymes).
Thyrotoxicosis-induced bone resorption can result in mild hypercalcemia. Volume expansion and glucocorticoid replacement can correct the hypercalcemia that occasionally occurs in patients with adrenal insufficiency. Pheo-chromocytoma is thought to cause hypercalcemia through the production of PTHrP.