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Injury can also affect the ligaments, cartilage, and bones within the joint. Pain is also a feature of joint inflammation (arthritis, such as rheumatoid arthritis and osteoarthritis) and infection, and extremely rarely it can be a cause of cancer of the joint.Pain within the joint is a common cause of shoulder pain, ankle pain, and knee pain.Joint pain is also referred to as arthralgia.njury can also affect the ligaments, cartilage, and bones within the joint. Pain is also a feature of joint inflammation (arthritis, such as rheumatoid arthritis and osteoarthritis) and infection, and extremely rarely it can be a cause of cancer of the joint.
Inflammation in the structures around your joint â Inflammation may occur: 1  in a bursa, which normally allows your muscles and tendons to run smoothly over your joints â this often happens in your shoulder and hip joints. 2  in the ligaments that hold your joints together â this frequently happens around your knee joint. in a bursa, which normally allows your muscles and tendons to run smoothly over your joints â this often happens in your shoulder and hip joints. 2  in the ligaments that hold your joints together â this frequently happens around your knee joint.