Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis. There may be associated erythema.
Blood Clots. A blood clot needs to be considered as a cause of calf pain, especially when the calf pain is not the immediate result of an injury. Blood clots can form is the deep veins of the leg, causing a blockage in circulation. This may cause swelling and pain in the calf.
Tight calf muscles may be caused by a compartment syndrome. This is where the muscle becomes too big for the sheath surrounding the muscle causing pressure, sometimes pain and restricted movement. Biomechanical problems of the foot or from running style can increase the strain on the calf muscles.