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Physiological and pathological changes are main inducing factors of diminished kidney function, which includes trauma, infection, inflammation, immune response, blood circulatory disorder, etc.
Acute kidney failure can occur for many reasons. Among the most common reasons are: acute tubular necrosis (ATN) severe or sudden dehydration; toxic kidney injury from poisons or certain medications; autoimmune kidney diseases, such as acute nephritic syndrome and interstitial nephritis; urinary tract obstruction; Reduced blood flow can damage your kidneys.