Itai-itai disease (ã¤ã¿ã¤ã¤ã¿ã¤ç, itai-itai byÅ? ), (literally: ouch-ouch disease) was the first documented case of mass cadmium poisoning in the world in Toyama Prefecture, Japan in 1950. The cadmium poisoning caused softening of the bones and kidney failures.
Weighted grades are number or letter grades that are assigned a numerical advantage when calculating a grade point average, or GPA.
Weighted Grades. Many teachers put assignments in a variety of categories and then weight them to calculate final grades. So finding the final average is not as simple as adding up the points and dividing by the total possible.A similar scenario might be like the following problem.eighted Grades. Many teachers put assignments in a variety of categories and then weight them to calculate final grades. So finding the final average is not as simple as adding up the points and dividing by the total possible. A similar scenario might be like the following problem.