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According to The Pill Book Guide to Medication For Your Dog and Cat (Kate A.W. Roby, VMD, et al, 1998), cats are started off at 1 mg of prednisone per pound that the cat weighs. This is given one or two times a day. When the cat seems better, one dose is given every other day until the cat is cured.
Your dog is on a massive dose of prednisone, which would be expected to cause polyuria and could lead to overflow incontinence. The maintenance dosage of prednisone for an adult human patient is 5-mg, so your dog should not be on more than that dosage if the drug is being given just for Addison's replacement.hat's what I was hoping you would say (about the weight). The dose of prednisone or prednisonlone that I recommend for dogs with Addison's is between 0.1-0.2 mg/kg/day. That calculates to 1.6-3.2 mg per day.