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Donât ignore possible physical symptoms of depression: Pain and other changes in your health can actually be the first signs of depression, and knowing about possible physical effects of depression may help you get diagnosed and treated earlier.
1 The causes of depression are not fully understood but are likely to be a complex combination of genetic, biological, environmental and psychosocial factors.  In addition to the mental symptoms, such as inappropriate feelings of guilt, physical ones may include problems with sleep and a loss of energy.