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On either 10 or 11 June 323 BC, Alexander died in the palace of Nebuchadnezzar II, in Babylon, at age 32. There are two different versions of Alexander's death and details of the death differ slightly in each.
How did Alexander the Great build his empire? Alexander the Great became king after his father, King Phillip II, died. Alexander began his conquest of the Persian Empire 334 B.C. with the Battle of Granicus. Alexander's forces destroyed the Persian forces. A year later, Alexander the Great, defeated the Persian army at the Battle of Issus and freed the Greek city-states of Asia Minor. He then captured Syrian and Egypt. Alexander built the city of Alexandria in Egypt as a center of business.