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Lumbosacral Radiculopathy Definition. Lumbosacral radiculopathy is a broad term referring to a range of symptoms associated with the nerves of the lumbosacral plexus in the lower back. The lumbosacral plexus encompasses the nerves that exit the spinal cord at the lumbar, sacral and coccygeal regions of the spine. Radiculopathy occurs when an anatomical abnormality has caused one or more of these nerves to become irritated, pinched or impinged.
Answers. Best Answer: Sunshine, a great question! A radiculopathy is a problem at the root of a nerve. So in your case of S-2 the problem would be something pushing against the nerve root at that level. A neuropathy is a term that is used for the cranial nerves, autonomic nervous system, or the peripheral nerves.t the horn level is a Motor Neuron Disease, at the spinal root level it is called a radicular problem or radiculopathy, and in the peripheral nerves then it is a neuropathy or peripheral nerve problem. Source(s): physical therapist. Richard C Â· 5 years ago. Thumbs up.