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This supports the idea that in embryos from wild-type mothers, dpp H~- mutations cause the transformation of dorsal into ven-tral epidermis. If tissue determined to become dorsal epidermis dies in the dpp rim-null embryos, then one should not see ventral or lateral tissue formed in the double-mutant combination.
DMD, the largest known human gene, provides instructions for making a protein called dystrophin. This protein is located primarily in muscles used for movement (skeletal muscles) and in heart (cardiac) muscle. Small amounts of dystrophin are present in nerve cells in the brain.he damaged cells weaken and die over time, causing the characteristic muscle weakness and heart problems seen in Duchenne and Becker muscular dystrophy. Genetics Home Reference provides information about familial dilated cardiomyopathy, which is also associated with changes in the DMD gene.