Indications for mitochondrial DNA whole genome sequencing in the following clinical scenarios: 1  Confirmation of a suspected clinical diagnosis of a mitochondrial DNA disorder. 2  Mitochondrial DNA disorders caused by specific point mutation(s) are detected by this testing: 3  Leber hereditary optic neuropathy (LHON).
Androgen antagonists are compounds which inhibit or antagonize the biosynthesis or actions of androgens. Abbot Mcintosh 0 7 years ago Insulin lowers the level of glucose in the blood, whereas glucagon raises it; therefore, glucagon is an antagonist of insulin.
Opioid antagonist. An opioid antagonist, or opioid receptor antagonist, is a receptor antagonist that acts on one or more of the opioid receptors. Naloxone and naltrexone are commonly used opioid antagonist drugs which are competitive antagonists that bind to the opioid receptors with higher affinity than agonists but do not activate the receptors. This effectively blocks the receptor, preventing the body from responding to opioids and endorphins.