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The serotonin transporter gene (5-HTT) is considered as a candidate gene for BPD as multiple lines of evidence have suggested that it plays an important role in suicide, impulsive behaviour, and emotional liability.ompared with healthy controls, patients with BPD showed higher frequencies of the 10 repeat of the VNTR marker and the S-10 haplotype, and fewer 12 repeat and L A -12 haplotype. These results suggest that the serotonin transporter gene may play a role in the aetiology of BPD.
Image Credit: Main Image: Gene Amplification, also known as gene duplication or chromosomal duplication, is a cellular process in which multiple copies of a gene are produced. The result is an amplification of the phenotype, or expressed trait, associated with the gene.ot all gene amplification has great importance to evolution. Sometimes, the amplified trait dies with the single organism that experiences the gene duplication. This happens when a gene is over expressed and the trait it codes for is expressed to a level that is unhealthy to the organism.