Social Determinants of Health. The complex, integrated, and overlapping social structures and economic systems that are responsible for most health inequities. These social structures and economic systems include the social environment, physical environment, health services, and structural and societal factors. Social determinants of health are shaped by the distribution of money, power, and resources throughout local communities, nations, and the world [9]. Socioeconomic Gradient in Health This term refers to the stepwise fashion health outcomes improve as socioeconomic position improves.
Causes. Maple syrup urine disease (MSUD) is caused by a gene defect. Persons with this condition cannot break down the amino acids leucine, isoleucine, and valine.
Maple syrup urine disease (MSUD) is a condition in which the body is unable to break down certain proteins. The condition is named for the sweet odor of the urine of untreated babies.orms of maple syrup urine disease (MSUD) vary widely in the severity of their signs. âClassic MSUDâ is the most common form and is seen in babies. Babies with classic MSUD usually begin showing signs shortly after birth. These signs include: 1  Poor appetite.