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Quick Answer. Endometrial hyperplasia is an abnormal thickening of the lining of the uterus, according to the American Congress of Obstetricians and Gynecologists. The condition usually develops during menopause and perimenopause when ovulation is irregular or absent. It can also occur in women affected by polycystic ovary syndrome or obesity.
Endometrial hyperplasia is an excessive or abnormal thickening of the lining of the uterus. This lining, called the endometrium, thickens every month in preparation for pregnancy. If pregnancy does not occur, the lining is shed. This shedding process is called a menstrual period or menstruation. Most women have a normal menstrual period approximately every 28 days.