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Quick Answer. Endometrial hyperplasia is an abnormal thickening of the lining of the uterus, according to the American Congress of Obstetricians and Gynecologists. The condition usually develops during menopause and perimenopause when ovulation is irregular or absent. It can also occur in women affected by polycystic ovary syndrome or obesity.
In medical parlance, thickening of uterus is known as Endometrial Hyperplasia. The endometrium is the lining of the uterus, that grows and thickens every month, in sexually mature women. It is shed during the menstrual period, in the absence of pregnancy.strogen builds or thickens the lining of the uterus, and progesterone controls its growth. Mid-cycle ovulation occurs and the egg is released from the ovary. In case the egg is not fertilized, it can result in a drop in the hormonal levels, causing a regular menstrual period.