When I was first diagnosed with thyroid cancer, I didn't feel any odd lumps or nodules in my neck, but I was suffering from muscle weakness, tiredness and getting constant colds. After a particularly nasty bug I noticed that my lymph nodes never seemed to go down in size.
SIRS is nonspecific and can be caused by ischemia, inflammation, trauma, infection, or several insults combined. Thus, SIRS is not always related to infection. Venn diagram showing overlap of infection, bacteremia, sepsis, systemic inflammatory response syndrome (SIRS), and multiorgan dysfunction.
WHAT CAUSES SCHMORL'S NODULES? Schmorl's nodules tend to occur after trauma to the spine that causes wear and tear to it over time. Usually, if repeated trauma caused the formation of Schmorl's nodule, the patient does not remember a specific motion that caused the pain to begin.