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Botox is remarkably safe, especially considering it's a powerful toxin. Occasionally, a mild headache that lasts a few hours may occur after an injection in muscles of the forehead. Very rarely, though, that headache may become excruciating and can last as long as a month.
Botox is a neurotoxin that temporarily paralyzes nerves. It is most commonly used in the face to minimize the frown muscles. The three areas commonly treated are the upper nose, forehead, and around the eyes. The result is a smoothing effect that lasts approximately 3 months.