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Quick Answer. Endometrial hyperplasia is an abnormal thickening of the lining of the uterus, according to the American Congress of Obstetricians and Gynecologists. The condition usually develops during menopause and perimenopause when ovulation is irregular or absent. It can also occur in women affected by polycystic ovary syndrome or obesity.
Endometrial hyperplasia is an abnormality of the lining of your uterus or endometrium. Your endometrium is what builds up and sheds each month in response to your regular cyclic hormonal changes. It is the major component of your monthly menstrual flow.