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Research suggests that taking L-arginine by mouth or intravenously (by IV) for up to 8 weeks increases blood flow in people with peripheral arterial disease. However, long-term use (up to 6 months) does not improve walking speed or distance in people with peripheral arterial disease.
Benefits of L-arginine. L-arginine has two effects: it turns into nitric oxide and helps the body build protein. These effects give L-arginine an array of potential benefits that range from heart health and chest pain to helping to build muscles, repair wounds, and improve male fertility.