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terminator codon mutations and hypofunctional genes responsible for various Î±-thalassemia syndromes [6]. Î±-thalassemia can be suspected based on factors such as a family history of anemia and ethnic and geographic backgrounds, particularly if the patients
Point mutations in Î² globin. different types of Î² thalassaemia are caused by different location and types of mutations in the Î² globin gene. but missense mutations of Î² globin gene result in specific phenotypes (sickle cell) and not Î² thalassaemia.