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Added 5 Mar 2011: Ok, I learned that the half-life of Suboxone is 36 hours, according to the Suboxone counselor I spoke to today. That is for one dose. This individual couldn't say how to calculate how long the stuff clears out of your system if you are taking a sub-clinical dose.
Suboxone is a very effective binder to the mu opiate receptor, its â¦ effective half life is 36 hours. So it would take 72 hours to leave your body entirely. Vicodin comes in small doses, to be effective within that 72 hours you would need a very large dose.