When I was first diagnosed with thyroid cancer, I didn't feel any odd lumps or nodules in my neck, but I was suffering from muscle weakness, tiredness and getting constant colds. After a particularly nasty bug I noticed that my lymph nodes never seemed to go down in size.
SIRS is nonspecific and can be caused by ischemia, inflammation, trauma, infection, or several insults combined. Thus, SIRS is not always related to infection. Venn diagram showing overlap of infection, bacteremia, sepsis, systemic inflammatory response syndrome (SIRS), and multiorgan dysfunction.
This is a group of conditions caused by dysfunctional or poorly formed blood cells. These syndromes happen when an event of some sort goes wrong in the bone marrow which is the spongy matter inside the bones and is where blood cells are created. There is no cure for this group of syndromes.