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Botox is remarkably safe, especially considering it's a powerful toxin. Occasionally, a mild headache that lasts a few hours may occur after an injection in muscles of the forehead. Very rarely, though, that headache may become excruciating and can last as long as a month.
Side effects of Botox include: allergic reactions, rash, itching, headache, neck or back pain, muscle stiffness, difficulty swallowing, shortness of breath, nausea, diarrhea, stomach pain, loss of appetite, muscle weakness, injection site reactions including; bruising, bleeding, pain, redness, swelling, or ; infection, fever, cough, sore throat,