Grandfathered, The Grinder Cancelled. Fox just wiped out half of its Tuesday-night comedy block. The network has cancelled rookie sitcoms Grandfathered and The Grinder, TVLine has learned. Also axed: Fellow freshman comedies Bordertown. and Cooper Barrettâs Guide To Surviving Life. Grinder leading man Rob Lowe broke news of his showâs demise on Twitter Thursday.
An aspartate aminotransferase (AST) test measures the amount of this enzyme in the blood. AST is normally found in red blood cells, liver, heart, muscle tissue, pancreas, and kidneys. AST formerly was called serum glutamic oxaloacetic transaminase (SGOT).
AST catalyzes the reversible transfer of an Î±-amino group between aspartate and glutamate and, as such, is an important enzyme in amino acid metabolism. AST is found in the liver, heart, skeletal muscle, kidneys, brain, and red blood cells.Serum AST level, serum ALT (alanine transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels.s a prototypical transaminase, AST relies on PLP (Vitamin B6) as a cofactor to transfer the amino group from aspartate or glutamate to the corresponding ketoacid.