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Glucosamine is a naturally occurring substance found in the fluid around our joints. It is naturally present in animal bones, bone marrow, shellfish and fungi. Glucosamine plays a vital role in building cartilage and is commonly consumed as a supplement by people with arthritis, especially osteoarthritis. Glucosamine, especially glucosamine sulfate, is harvested from the shells of shellfish and put into dietary supplements. It can also be made in the laboratory.
Commonly sold forms of glucosamine are glucosamine sulfate, glucosamine hydrochloride, and N-acetylglucosamine. Glucosamine is often sold in combination with other supplements such as chondroitin sulfate and methylsulfonylmethane.Of the three commonly available forms of glucosamine, only glucosamine sulfate is given a likely effective rating for treating osteoarthritis.lucosamine is one of the most abundant monosaccharides. It is produced commercially by the hydrolysis of crustacean exoskeletons or, less commonly, by fermentation of a grain such as corn or wheat. Glucosamine appears to be safe for use as a dietary supplement; effectiveness has not been established for any condition.