When I was first diagnosed with thyroid cancer, I didn't feel any odd lumps or nodules in my neck, but I was suffering from muscle weakness, tiredness and getting constant colds. After a particularly nasty bug I noticed that my lymph nodes never seemed to go down in size.
SIRS is nonspecific and can be caused by ischemia, inflammation, trauma, infection, or several insults combined. Thus, SIRS is not always related to infection. Venn diagram showing overlap of infection, bacteremia, sepsis, systemic inflammatory response syndrome (SIRS), and multiorgan dysfunction.
Familial, or hereditary, amyloidosis (AF). This is a rare form that is passed down through families. It is caused by an abnormal amyloid transthyretin (TTR) protein, which is made in the liver. This protein is responsible for the most common forms of hereditary amyloidosis. Senile systemic amyloidosis (SSA).