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Layers of the Heart Wall. The wall of the heart consists of three layers: the epicardium (external layer), the myocardium (middle layer) and the endocardium (inner layer). The epicardium is the thin, transparent outer layer of the wall and is composed of delicate connective tissue.
  Three layers of tissue form the heart wall. The outer layer of the heart wall is the epicardium, the middle layer is the myocardium, and the inner layer is the endocardi â¦ um.24 people found this useful.aking the world better, one answer at a time. The walls of the heart are made from an epithelial tissue. The walls of the heart are made from an epithelial tissue.