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Those of us in the animal sheltering and rescue world usually recommend early-age spay/neuter at 8 weeks of age, or as soon as possible after that. Promoting early-age spay neuter is part of the social responsibility we feel to do all we can to reduce 5,000 dogs and cats euthanized in animal shelters every day. We see the number of puppies and kittens barely 6 months old that come to shelters, suffering from such an early pregnancy.
They have to be at least 8 weeks old to be spayed or neutered. It doesn't have to be done so early, but it should be done sooner rather than later, as studies have shown that cats that are spayed/neutered later are at greater risk for certain serious conditions and diseases, such as breast cancer.