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Quick Answer. Endometrial hyperplasia is an abnormal thickening of the lining of the uterus, according to the American Congress of Obstetricians and Gynecologists. The condition usually develops during menopause and perimenopause when ovulation is irregular or absent. It can also occur in women affected by polycystic ovary syndrome or obesity.
Endometrial hyperplasia is an abnormal thickening or growth of the lining of the uterus. There are several varieties: Simple hyperplasia. Complex hyperplasia without atypia-this type is a little thicker than simple hyperplasia, and has more crowding and abnormal architecture to the glands.he uterus has three layers: the endometrium (or inner lining), the myometrium (muscle), and the serosa (outer surface lining, the same as the lining of the abdominal cavity).