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Researchers do know from twin studies that genetics plays a role in personality disorders. Environmental factors, such as childhood abuse, neglect and separation from caregivers, as well as brain abnormalities, emotion regulation, impulsivity, aggression and serotonin levels all play a role.ecause many personality domains are heritable, borderline personality disorder may be a result of a genotype interacting with adverse environmental factors. This would in turn lead to the expression of borderline symptoms or other dysfunctional personality traits.
They found, in addition to the 10 previously known gene regions for CAD, 13 new gene regions. The findings were unexpected. âThe majority reside in gene regions that were not previously suspected in the pathogenesis of CAD,â the researchers write. Genetics play a major role in the development of heart disease. Identifying genes that put people at increased risk could aid in the development of both prevention strategies and new treatments. But first, more study is needed to determine how the genes contribute to CAD.