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In children and adolescents, risperidone may be more effective than lithium or divalproex, but has more metabolic side effects. As maintenance therapy, risperidone is effective for the prevention of manic episodes but not depressive episodes.
Risperidone, a medication used to treat mental disorders, may cause weight gain. Photo Credit Jupiterimages/Comstock/Getty Images. Risperidone is a prescription medication used to control the symptoms associated with a variety of mental disorders.Risperidone use may cause several side effects, including significant weight gain.isperidone and Weight. Risperidone does not induce weight loss; by contrast, risperidone use is associated with an increase in appetite, a rise in blood cholesterol levels and potentially significant weight gain in up to 5 percent of its users.