Hanks, who has won two Oscars but hasnât been nominated in 13 years, was overlooked for both âCaptain Phillipsâ and âSaving Mr. Banks.â. SNUB: âInside Llewyn Davis.â Even with nine best picture nominees, the Coen brothers, a perennial Academy favorite, lost out this time in the top category with their musical dramedy.
Anti-parallel strands. The DNA molecule is composed of two strands held together by hydrogen bonds. A single strand is different at its two ends. One end is called 5' (5 prime), the other is called 3' (3 prime). The names come from the notation for the two sugar carbon atoms which participate in the phosphodiester bonds. The different strands in the helix run in opposite (anti-parallel) directions. At each end of the double helix, one strand is 5' and the other is 3'. In the illustration, the 3' end is shown with a red arrowhead and the 5' end with the yellow connector.
Helicase, made of six proteins arranged in a ring shape, unwinds the DNA double helix into two individual strands. Single-strand binding proteins, or SSBs, are tetramers that coat the single-stranded DNA.This prevents the DNA strands from reannealing to form double-stranded DNA.Primase is an RNA polymerase that synthesizes the short RNA primers needed to start the strand replication process. DNA polymerase is a hand-shaped enzyme that strings nucleotides together to form a DNA strand.his prevents the DNA strands from reannealing to form double-stranded DNA. Primase is an RNA polymerase that synthesizes the short RNA primers needed to start the strand replication process. DNA polymerase is a hand-shaped enzyme that strings nucleotides together to form a DNA strand.