When I was first diagnosed with thyroid cancer, I didn't feel any odd lumps or nodules in my neck, but I was suffering from muscle weakness, tiredness and getting constant colds. After a particularly nasty bug I noticed that my lymph nodes never seemed to go down in size.
SIRS is nonspecific and can be caused by ischemia, inflammation, trauma, infection, or several insults combined. Thus, SIRS is not always related to infection. Venn diagram showing overlap of infection, bacteremia, sepsis, systemic inflammatory response syndrome (SIRS), and multiorgan dysfunction.
In some cases, MDS is caused by chemotherapy used to treat a different disease. This is called secondary MDS. In most cases, the cause of MDS is unknown. There are many different types of MDS. Doctors look at cells in the blood and in the bone marrow to determine what type of MDS a patient has. Long-term survival and the risk that MDS might turn into AML are different for each type of MDS.