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Research suggests that taking L-arginine by mouth or intravenously (by IV) for up to 8 weeks increases blood flow in people with peripheral arterial disease. However, long-term use (up to 6 months) does not improve walking speed or distance in people with peripheral arterial disease.
Proponents claim that L-arginine can also benefit: 1  colds. 2  dementia. 3  hair. 4  high blood pressure. 5  intermittent claudication. 6  interstitial cystitis. 7  male infertility. 8  migraines. 9  preeclampsia. 10  sexual dysfunction in women.