All cells require folic acid and it can diffuse easily into human cells. But the vitamin cannot enter bacterial cells and thus bacteria must make their own. The sulfa drugs such as sulfonamides inhibit a critical enzyme--dihydropteroate synthase--in this process. Once the process is stopped, the bacteria can no longer grow.
Sonoma Countyâs natural beauty and moderate temperatures seldom dip below freezing, even in the winter. The areaâs 25- to 30-inch annual rainfall happens primarily from November through April. January â Average high /low. Inland: 58 F (14 C) / 36 F (2 C) Coast: 56 F (13 C) / 35 F (2 C)
So where is Sonoma again? Located just 35 miles north of the San Francisco Bay area, Sonoma County has a total land area of 1,576 square miles and boasts 76 miles of Pacific coastline on the west. Over 100 miles of the Russian River wind through Sonoma County bringing the valley's vineyards a great natural resource.