$500 Bill. The Treasury minted several versions of the $500 bill, featuring a portrait of President William McKinley on the front. The last $500 bill rolled off the presses in 1945, and was formally discontinued 24 years later in 1969. Like all the bills featured here, the $500 bill remains legal tender.
Confidence votes 21. Selective breeding has been a way of enhancing preferable genetic qualities in mainly dogs, cats and horses. Often the results can cause mild to severe problems.For example ;breeding for the flat face of the pekingese can cause breathing problems and jaw and teeth deformities.ften the results can cause mild to severe problems.For example ;breeding for the flat face of the pekingese can cause breathing problems and jaw and teeth deformities.
lactose intolerance-caused by mutations in the LCT gene. At least nine LCT gene mutations cause congenital lactase deficiency, also called congenital alactasia. In this disorder, infants are unable to break down lactose (lactose intolerance) in breast milk or formula.The LCT gene mutations change single protein building blocks (amino acids) in the lactase enzyme or result in an enzyme that is abnormally short.he mutations are believed to interfere with the function of the lactase enzyme, leading to undigested lactose in the small intestine and causing severe diarrhea. Lactose intolerance in adulthood is caused by gradually decreasing activity (expression) of the LCT gene after infancy, which occurs in most humans.