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Mastoiditis is a serious bacterial infection that affects the mastoid bone behind the ear. It's usually more common in children, although adults can also sometimes be affected. The mastoid bone has a honeycomb-like structure that contains air spaces called mastoid cells.
The mastoid is a part of the side (temporal bone) of the skull. It can be felt as a bony bump just behind and slightly above the level of the earlobe. The mastoid has been described as resembling a honeycomb of tiny partitioned-off airspaces. The mastoid is connected with the middle ear, so that when there is a collection of fluid in the middle ear, there is usually also a slight collection of fluid within the airspaces of the mastoid.