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Drinking coffee before blood test can affect the results of tests that measure blood sugar and cholesterol levels. Coffee contains caffeine that is easily absorbed into the system at a fast rate. Caffeine can temporarily raise blood sugar levels resulting to an inaccurate fasting blood sugar (FBS) result.
Quick Answer. Coffee is one of the specific items Mayo Clinic advises people to avoid while fasting before a cholesterol test. Typically, doctors ask people to fast for nine to 12 hours before a cholesterol test and drink nothing but water. Keep Learning.