All cells require folic acid and it can diffuse easily into human cells. But the vitamin cannot enter bacterial cells and thus bacteria must make their own. The sulfa drugs such as sulfonamides inhibit a critical enzyme--dihydropteroate synthase--in this process. Once the process is stopped, the bacteria can no longer grow.
Sonoma Countyâs natural beauty and moderate temperatures seldom dip below freezing, even in the winter. The areaâs 25- to 30-inch annual rainfall happens primarily from November through April. January â Average high /low. Inland: 58 F (14 C) / 36 F (2 C) Coast: 56 F (13 C) / 35 F (2 C)
Harvest Fair. October 6 - 8. The Harvest Fair marks its 43rd year of showcasing our countys grand harvest which continues to result in world-class wines, beer, cider and a plethora of culinary wealth. The epicenter of the Harvest Fair is still the Grand Tasting Pavilion, which features over 150 Sonoma County wineries.