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Those of us in the animal sheltering and rescue world usually recommend early-age spay/neuter at 8 weeks of age, or as soon as possible after that. Promoting early-age spay neuter is part of the social responsibility we feel to do all we can to reduce 5,000 dogs and cats euthanized in animal shelters every day. We see the number of puppies and kittens barely 6 months old that come to shelters, suffering from such an early pregnancy.
The mother cat can be spayed as soon as the kittens are weaned, usually when they around 10 to 12 weeks old. Some shelters will have their kittens neutered at 8 weeks - 12 weeks or 2.0 lbs also. Neutering does not make cats fat or change their personalities regardless of when it's done.