1.JOHN SMITH. Newton Jasper Smith, a son of James John and Emma (Rogers) Smith, was born in 1863 and died in 1927. He married Permilia Spencer. Permilia, a daughter of John White and Permilia (Andrews) Spencer, was. born in 1864 and died in 1923. Children of Newton Jasper and Permilia (Spencer) Smith.oseph Nelson Smith, a son of John and Frances (Cochran) Smith, was born. 54 in Roane County VA (WV) and died in 1944. He. married Anna Liza Crookshank in 1879. Anna, a daughter of David S. Crookshank, was born in 1863 and died in 1952.
Most opioids are derived from the opium poppy and include heroin, morphine, codeine and hydrocodone. Methadone is a synthetic opioid that is structurally dissimilar to naturally derived products, even though it acts at the same sites in the body.
Methadone, also known as Dolophine among other brand names, is a synthetic opioid. Mainly used for treatment of severe chronic pain medication, due to its long duration of action and strong analgesic effect.ethadone withdrawal symptoms are considered more severe than other opiates as morphine or heroin and it could last much longer, sometimes even 4 to weeks to 16 weeks.