All cells require folic acid and it can diffuse easily into human cells. But the vitamin cannot enter bacterial cells and thus bacteria must make their own. The sulfa drugs such as sulfonamides inhibit a critical enzyme--dihydropteroate synthase--in this process. Once the process is stopped, the bacteria can no longer grow.
Sonoma Countyâs natural beauty and moderate temperatures seldom dip below freezing, even in the winter. The areaâs 25- to 30-inch annual rainfall happens primarily from November through April. January â Average high /low. Inland: 58 F (14 C) / 36 F (2 C) Coast: 56 F (13 C) / 35 F (2 C)
The total sales tax rate in any given location can be broken down into state, county, city, and special district rates. California has a 6.00% sales tax and Sonoma County collects an additional 0.25%, so the minimum sales tax rate in Sonoma County is 6.25% (not including any city or special district taxes). This table shows the total sales tax rates for all cities and towns in Sonoma County, including all local taxes.