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Those of us in the animal sheltering and rescue world usually recommend early-age spay/neuter at 8 weeks of age, or as soon as possible after that. Promoting early-age spay neuter is part of the social responsibility we feel to do all we can to reduce 5,000 dogs and cats euthanized in animal shelters every day. We see the number of puppies and kittens barely 6 months old that come to shelters, suffering from such an early pregnancy.
Best Answer: For female, sexual maturity can be as soon as 4 months old. For male, the normal age is between 5-6 months of age. Therefore, it will be very important to neuter your kittens before that. Early spay and neuter can be performed at the age of 8 weeks old or when they weigh at least 2 lbs. There are no side effects with early spay and neuter and does not cause any development of behavioral problems later on. Cats are opportunist breeder. They can mate with any other cats, mother son, father daughter, brother and sisters.