Hanks, who has won two Oscars but hasnât been nominated in 13 years, was overlooked for both âCaptain Phillipsâ and âSaving Mr. Banks.â. SNUB: âInside Llewyn Davis.â Even with nine best picture nominees, the Coen brothers, a perennial Academy favorite, lost out this time in the top category with their musical dramedy.
Anti-parallel strands. The DNA molecule is composed of two strands held together by hydrogen bonds. A single strand is different at its two ends. One end is called 5' (5 prime), the other is called 3' (3 prime). The names come from the notation for the two sugar carbon atoms which participate in the phosphodiester bonds. The different strands in the helix run in opposite (anti-parallel) directions. At each end of the double helix, one strand is 5' and the other is 3'. In the illustration, the 3' end is shown with a red arrowhead and the 5' end with the yellow connector.
A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface.Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome.Each DNA spot contains picomoles (10 â12 moles) of a specific DNA sequence, known as probes (or reporters or oligos).NA microarrays can be used to detect DNA (as in comparative genomic hybridization), or detect RNA (most commonly as cDNA after reverse transcription) that may or may not be translated into proteins. The process of measuring gene expression via cDNA is called expression analysis or expression profiling.