When I was first diagnosed with thyroid cancer, I didn't feel any odd lumps or nodules in my neck, but I was suffering from muscle weakness, tiredness and getting constant colds. After a particularly nasty bug I noticed that my lymph nodes never seemed to go down in size.
SIRS is nonspecific and can be caused by ischemia, inflammation, trauma, infection, or several insults combined. Thus, SIRS is not always related to infection. Venn diagram showing overlap of infection, bacteremia, sepsis, systemic inflammatory response syndrome (SIRS), and multiorgan dysfunction.
Mutations in the genes for the following normal proteins may cause hereditary systemic amyloidosis, in order from the most to the least common: transthyretin (TTR)- ATTR amyloid â over 100 known variants, of which the most common is Familial Amyloid Polyneuropathy (FAP).