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This supports the idea that in embryos from wild-type mothers, dpp H~- mutations cause the transformation of dorsal into ven-tral epidermis. If tissue determined to become dorsal epidermis dies in the dpp rim-null embryos, then one should not see ventral or lateral tissue formed in the double-mutant combination.
Entrez Gene Summary for ASPM Gene. This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts.Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis.SPM (Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila)) is a Protein Coding gene.