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Nephritis is inflammation of the kidneys and may involve the glomeruli, tubules, or interstitial tissue surrounding the glomeruli and tubules. Lupus nephritis is inflammation of the kidney caused by systemic lupus erythematosus (SLE), a disease of the immune system. 2  Athletic nephritis is nephritis resulting from strenuous exercise.
Interstitial nephritis is a kidney disorder in which the spaces between the kidney tubules become swollen (inflamed). This can cause problems with the way your kidneys work. Interstitial nephritis may be temporary (acute), or it may be long-lasting (chronic) and get worse over time. The acute form of interstitial nephritis is most often caused by side effects of certain drugs. The following can cause interstitial nephritis: Allergic reaction to a drug (acute interstitial allergic nephritis).