All cells require folic acid and it can diffuse easily into human cells. But the vitamin cannot enter bacterial cells and thus bacteria must make their own. The sulfa drugs such as sulfonamides inhibit a critical enzyme--dihydropteroate synthase--in this process. Once the process is stopped, the bacteria can no longer grow.
Sonoma Countyâs natural beauty and moderate temperatures seldom dip below freezing, even in the winter. The areaâs 25- to 30-inch annual rainfall happens primarily from November through April. January â Average high /low. Inland: 58 F (14 C) / 36 F (2 C) Coast: 56 F (13 C) / 35 F (2 C)
Sonoma County Harvest Fair - Taste the Best of Sonoma County. Taste the Best of Sonoma County - October 6 - 8, 2017. In 2017, the Harvest Fair will mark itâs 43rd year of showcasing our countyâs grand harvest which continues to result in world-class wines, award winning beer and a plethora of culinary wealth. In 2015, with over 26,000 votes, the Harvest Fair was voted the Best Annual Festival of Sonoma County bestowed by The Press Democrat readers.