Combination therapies with agents such as indoleamine 2,3-dioxygenase (IDO) inhibitors may have the potential to synergize with immunotherapeutic approaches to improve immune function against tumor cells.ombination therapies, such as with IDO inhibitors, have the potential to synergize with immunotherapeutic approaches.â Completion of the study is anticipated for November 2017. Alex A. Adjei, MD, PhD, FACP.
Cavities are caused by tooth decay â a process that occurs over time. Plaque forms. Your mouth naturally contains many types of bacteria. Some thrive on food and drinks that contain certain forms of sugar. When these sugars aren't cleaned off your teeth, the bacteria quickly begin feeding on them and producing acids.
Tooth decay, also known as a cavity, or cavities, occurs when bacteria living in your mouth make acid that then begins to eat away at your teeth. Untreated tooth decay may cause infection, extreme pain and the loss of tooth. The decay process begins with the unnoticeable damage to the enamel of your teeth and then steadily progresses to deeper layers of the tooth, eventually leading to the pulp.