Terminal illness is a disease that cannot be cured or adequately treated and that is reasonably expected to result in the death of the patient within a short period of time.he six-month standard is arbitrary, and best available estimates of longevity may be incorrect. Consequently, though a given patient may properly be considered terminal, this is not a guarantee that the patient will die within six months.
1 Stop metformin if the eGFR is below 30 ml/minute/1.73m2.  Prescribe metformin with caution for those at risk of a sudden deterioration in kidney function and those at risk of eGFR falling below 45ml/minute/1.73m2.
To make sure metformin is safe for you, tell your doctor if you have: 1  kidney disease; 2  liver disease; 3  a history of heart disease or recent heart attack;  if you have recently taken chlorpropamide; 1  or. if you are over 80 years old and have not recently had your kidney function checked.