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Added 5 Mar 2011: Ok, I learned that the half-life of Suboxone is 36 hours, according to the Suboxone counselor I spoke to today. That is for one dose. This individual couldn't say how to calculate how long the stuff clears out of your system if you are taking a sub-clinical dose.
Suboxone is made of two drugs-buprenorphine and naloxone. The buprenorphine is what sticks around in your system and prevents withdrawl. It has a 36 hour half-life. So if yo â¦ u took 2mg of suboxone one time only, 36 hours later you'd have 1mg left in your system. 36 hours after that you'd have .5 mg in your system.Another 36 hours and there'd be .25mg left and so on.o if yo â¦ u took 2mg of suboxone one time only, 36 hours later you'd have 1mg left in your system. 36 hours after that you'd have .5 mg in your system. Another 36 hours and there'd be .25mg left and so on.