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Researchers do know from twin studies that genetics plays a role in personality disorders. Environmental factors, such as childhood abuse, neglect and separation from caregivers, as well as brain abnormalities, emotion regulation, impulsivity, aggression and serotonin levels all play a role.ecause many personality domains are heritable, borderline personality disorder may be a result of a genotype interacting with adverse environmental factors. This would in turn lead to the expression of borderline symptoms or other dysfunctional personality traits.
Genetics play a major role in the development of heart disease. Identifying genes that put people at increased risk could aid in the development of both prevention strategies and new treatments. But first, more study is needed to determine how the genes contribute to CAD.