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The serotonin transporter gene (5-HTT) is considered as a candidate gene for BPD as multiple lines of evidence have suggested that it plays an important role in suicide, impulsive behaviour, and emotional liability.ompared with healthy controls, patients with BPD showed higher frequencies of the 10 repeat of the VNTR marker and the S-10 haplotype, and fewer 12 repeat and L A -12 haplotype. These results suggest that the serotonin transporter gene may play a role in the aetiology of BPD.
BRAF gene mutation testing has emerged as an important tool for diagnosis, prognosis, treatment, and predicting patient outcome in response to targeted therapy.Evidence indicates BRAF gene mutation testing has a role in the following:he BRAF gene mutation test result is positive (ie, a mutation is present) if V600E is found in the BRAF gene. V600E is the most common gene mutation for the BRAF gene and is the most common mutation tested for in clinical laboratories.