1.JOHN SMITH. Newton Jasper Smith, a son of James John and Emma (Rogers) Smith, was born in 1863 and died in 1927. He married Permilia Spencer. Permilia, a daughter of John White and Permilia (Andrews) Spencer, was. born in 1864 and died in 1923. Children of Newton Jasper and Permilia (Spencer) Smith.oseph Nelson Smith, a son of John and Frances (Cochran) Smith, was born. 54 in Roane County VA (WV) and died in 1944. He. married Anna Liza Crookshank in 1879. Anna, a daughter of David S. Crookshank, was born in 1863 and died in 1952.
Most opioids are derived from the opium poppy and include heroin, morphine, codeine and hydrocodone. Methadone is a synthetic opioid that is structurally dissimilar to naturally derived products, even though it acts at the same sites in the body.
Methadone was first marketed as âDolophineâ and was used as an analgesic (a painkiller) for the treatment of severe pain. It is still occasionally used for pain relief. Methadone is now primarily used today for the treatment of narcotic addiction. The effects of methadone are longer-lasting than those of morphine-based drugs. Methadoneâs effects can last up to 24 hours, thereby permitting administration only once a day in heroin detoxification and maintenance programs.