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terminator codon mutations and hypofunctional genes responsible for various Î±-thalassemia syndromes [6]. Î±-thalassemia can be suspected based on factors such as a family history of anemia and ethnic and geographic backgrounds, particularly if the patients
Sickle cell anemia is a genetic disease that causes the red blood cells to develop as a crescent shape. This can lead to blood clots when the red blood cells clump together. The disease also causes anemia, fatigue, and shortness of breath.ay Sachs Disease. Tay Sachs is a recessive genetic disease caused by a mutation in the hexosaminidase A gene, HEXA. A mutation in the gene causes fat molecules to accumulate in the brain.