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Researchers do know from twin studies that genetics plays a role in personality disorders. Environmental factors, such as childhood abuse, neglect and separation from caregivers, as well as brain abnormalities, emotion regulation, impulsivity, aggression and serotonin levels all play a role.ecause many personality domains are heritable, borderline personality disorder may be a result of a genotype interacting with adverse environmental factors. This would in turn lead to the expression of borderline symptoms or other dysfunctional personality traits.
Gene regulation is the switching on or off of certain genes in order to create different effects. This is vital so that cells are able to react to changes, and so that special â¦ ised cells can perform different functions. 2 people found this useful.