And you may be familiar with some of the symptoms: anxiety, depression, distractability, irritability or frequent crying. Through counseling and guidance, I help teens and college students de-stress and regain a sense of confidence and enjoyment in life.
Comparing carvedilol and metoprolol: results of the COMET trial. The Carvedilol or Metoprolol European Trial (COMET) compared overall mortality in patients with heart failure, randomised to receive either carvedilol or metoprolol tartrate.t is important to note that in the COMET trial, carvedilol was compared with metoprolol tartrate. The MERIT-HF trial compared metoprolol succinate to placebo and it was found that metoprolol succinate reduced the mortality rate by 34% in patients with heart failure.
CHOICE OF BETA BLOCKER. Carvedilol (Coreg), bisoprolol (Zebeta) and metoprolol succinate (Toprol XL) have all been shown to be beneficial in patients with chronic heart failure. At present, the U.S. Food and Drug Administration has labeled only carvedilol for use in slowing the progression of chronic heart failure.atients with severe heart failure, especially inotrope-dependent and hospitalized patients, and those with hypotension, bradycardia or higher than first-degree heart block are not considered appropriate candidates for beta blocker therapy. Optimal diuresis is essential for maximal tolerability.