102 video review lessons. Review AP US History by watching and listening to over 18 hours worth of videos carefully coordinated to the AP US History syllabus. 290 AP US History practice questions. Test your understanding of each concept without having to take an entire AP US History practice exam. Customized AP US History study plan.
In fact the most common cause of microcytic anemia is iron deficiency, and in low risk patients physicians often confirm the diagnosis of iron deficiency as the cause by a good response to iron therapy.
Therefore, if the increase in MCV is not related to macrocytic anemia, the mean cell hemoglobin concentration (MCHC) also increases in proportion. Causes of macrocytosis are many and range from benign to malignant; thus, a complete workup to determine etiology is essential.itamin B-12 deficiency is a cause of macrocytosis. Because DNA synthesis requires cyanocobalamin (vitamin B-12) as a cofactor, a deficiency of the vitamin leads to decreased DNA synthesis in the erythrocyte, thus resulting in macrocytosis.