When I was first diagnosed with thyroid cancer, I didn't feel any odd lumps or nodules in my neck, but I was suffering from muscle weakness, tiredness and getting constant colds. After a particularly nasty bug I noticed that my lymph nodes never seemed to go down in size.
SIRS is nonspecific and can be caused by ischemia, inflammation, trauma, infection, or several insults combined. Thus, SIRS is not always related to infection. Venn diagram showing overlap of infection, bacteremia, sepsis, systemic inflammatory response syndrome (SIRS), and multiorgan dysfunction.
â¢ Triplet expansion repeat mutations can cause fragile X syndrome or Huntington's disease, by modification of gene expression or gain of function, respectively. â¢ Defective genes are often inherited from the parents. In this case, the genetic disorder is known as a hereditary disease.