When I was first diagnosed with thyroid cancer, I didn't feel any odd lumps or nodules in my neck, but I was suffering from muscle weakness, tiredness and getting constant colds. After a particularly nasty bug I noticed that my lymph nodes never seemed to go down in size.
SIRS is nonspecific and can be caused by ischemia, inflammation, trauma, infection, or several insults combined. Thus, SIRS is not always related to infection. Venn diagram showing overlap of infection, bacteremia, sepsis, systemic inflammatory response syndrome (SIRS), and multiorgan dysfunction.
The cause of MDS remains unknown. It occasionally develops after treatment with drugs or radiation for another medical condition, or after exposure to chemicals such as benzene or toluene. MDS occurs in older patients, often age 65 or older, which suggests that age may be the strongest risk factor for developing MDS.