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Research suggests that taking L-arginine by mouth or intravenously (by IV) for up to 8 weeks increases blood flow in people with peripheral arterial disease. However, long-term use (up to 6 months) does not improve walking speed or distance in people with peripheral arterial disease.
While the long list of l-arginine benefits continue to be studied, its heart health benefits get most of the attention, but other l-arginine benefits include: 1  Improves recovery after injury or extensive exercise. 2  Accelerated wound healing. 3  Better kidney function.  Immune system and hormone 1  support. Cholesterol support.  Blood pressure support.