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Quick Answer. Endometrial hyperplasia is an abnormal thickening of the lining of the uterus, according to the American Congress of Obstetricians and Gynecologists. The condition usually develops during menopause and perimenopause when ovulation is irregular or absent. It can also occur in women affected by polycystic ovary syndrome or obesity.
Thickening of uterine wall is also known as endometrial hyperplasia. 1  The condition is often observed in women who are nearing their menopause of have reached menopause. 2  This is because most of the time, changes or imbalance of estrogen and progesterone hormones occurs during this period.reatment For Thickening Of The Uterus. 1  The treatment of thickened uterus lining may depend on several factors such as the age of a woman, the severity of the symptoms and the risk of developing endometrial cancer.