What is DUEXIS Â® (ibuprofen and famotidine)? DUEXIS contains two medicines: ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and famotidine, a histamine H 2-receptor antagonist.
Various factors contribute to foot and ankle swelling during pregnancy. For starters, your body retains more fluid during pregnancy. Also, your growing uterus puts pressure on your veins, which impairs return of blood to your heart. This can lead to swelling in the legs, ankles and feet.
Puffy ankles are common during pregnancy and though it causes discomfort to you it is a sign that your pregnancy is going just the way it should be. Almost 3 in every 4 pregnant women experience edema, and it starts somewhere around weeks 22 and 27 of pregnancy.