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[4,5] The accelerated vaccination schedule for monovalent hepatitis B vaccine, administered on days 0, 7 and 21, rapidly induces long-lasting (>12 months) hepatitis B antibodies (anti-HBs) and high rates of seroprotection.
The accelerated vaccination schedule calls for vaccine doses administered at days 0, 7, and 21â30; a booster should be administered at 12 months to promote long-term immunity. A combined hepatitis A and hepatitis B vaccine can also be used on the same 3-dose schedule (0, 7, and 21â30 days), with a booster at 12 months.