Owing to melatonin's antioxidant properties, the use of melatonin for the prevention of postoperative pericardial adhesion formation has been investigated. Twelve dogs received pericardial abrasions to promote adhesion and were randomized to receive either melatonin 10 mg/kg plus ethanol 5% in 10 mL sodium chloride or 10 mL sodium chloride dilution with ethanol 5%.
Definition of multifactorial. 1  1 : having characters or a mode of inheritance dependent on a number of genes at different loci. 2  2 or multifactorplay \-Ëfak-tÉr\ : having, involving, or produced by a variety of elements or causes.
Effects of those genes are cumulative, i.e. no single gene is considered to be dominant or recessive to another. On the other hand, multifactorial inheritance describes a trait whose manifestations are determined by two or more genes, accompanied by environmental factors.ounseling for multifactorial disorders. A number of factors can influence the recurrence risk in multifactorial disorders, which should be taken into account when counseling. In general, the recurrence risk is slightly greater for consanguineous parents when compared to those who are unrelated.