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The most common and less serious side effects of metformin are bloating, gas, stomach pain, weakness, diarrhea, constipation, heartburn, sneezing, headaches, cough, flushing of the skin, vomiting, runny nose, nausea and muscle pain.
Less commonly, runny nose can be caused by polyps, a foreign body, a tumor or migraine-like headaches. Causes of runny nose include: Acute sinusitis. Allergies. Chronic sinusitis. Churg-strauss syndrome. Common cold. Decongestant nasal spray overuse.