I have a '5 Way Reflector' that I want to use in my photography, which includes the following 5 options: 1  Gold reflective. 2  Silver reflective. 3  Gold/silver alternating pattern reflective. 4  White. 5  Scrim/opaque. 6  Black*.
The endoplasmic reticulum (ER) resident PKR-like kinase (PERK) is necessary for Akt activation in response to ER stress. We demonstrate that PERK harbors intrinsic lipid kinase, favoring diacylglycerol (DAG) as a substrate and generating phosphatidic acid (PA). This activity of PERK correlates with activation of mTOR and phosphorylation of Akt on Ser473. PERK lipid kinase activity is regulated in a phosphatidylinositol 3-kinase (PI3K) p85Î±-dependent manner. Moreover, PERK activity is essential during adipocyte differentiation.
Abstract. Protein and lipid kinases are two important classes of biomedically relevant enzymes. The expression and activity of many kinases are known to be dysregulated in a variety of diseases, and proteomic tools that can assess the presence and activity of these enzymes are likely to be useful for their evaluation.