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Stomach upset - Aspirin can upset a dog's stomach, which can interfere with the ultimate goal of relieving your dog's pain if he throws up the medication. Buffered aspirin is usually easier on a dog's stomach than non-buffered aspirin, especially if your vet advises you to give repeated doses.
Some of the Risks Associated with Aspirin For Dogs Are: 1  Aspirin are potent and have high toxicity. In the short term, aspirin may cause some serious gastrointestinal problem that may result in severe stomach irritation with side effects like vomiting, loss of appetite and diarrhea.