Antibiotics effective against procaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum . If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum.
Sofia: Annual Weather Averages. July is the hottest month in Sofia with an average temperature of 21Â°C (70Â°F) and the coldest is January at -1Â°C (30Â°F) with the most daily sunshine hours at 10 in July. The wettest month is April with an average of 70mm of rain. Average Temperature: Sofia. Loading weather data.
SOFIA is based on a Boeing 747SP wide-body aircraft. The aircraft has been modified to carry a 2.5 meter diameter reflecting telescope in the aft section of the fuselage. This telescope is designed for infrared astronomy observations at altitudes of about 41,000 feet (about 12 km) in the stratosphere.