Tofranil (imipramine): 1  Is generally used in children older than 6 years. 2  Has a success rate of 10 to 50 percent. 3  Starts working in a few days. 4  Is relatively inexpensive. 5  Will likely stop working when the child stops taking the medication.
The plateau pressure is the pressure applied (in positive pressure ventilation) to the small airways and alveoli. It is believed that control of the plateau pressure is important, as excessive stretch of alveoli has been implicated as the cause of ventilator induced lung injury.
Now letâs go back to peak and plateau pressures: Peak inspiratory pressure (PIP) = plateau pressure (Pplat) + pressure required to overcome airway resistance. Consequently, plateau pressure can never be higher than the peak, because thereâs always going to be intrinsic resistance which must be overcome.