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The function of the immunological barrier in the epididymis is to protect the sperm from attack by the immune system. Primarily, this function is carried out by the BEB, which sequesters sperm antigens and restricts entry of immunoglobulins and immune cells (Fig. 2 B).
Stem cell-derived blood-brain barrier gives more complete picture of Huntingtonâs disease. Like a sophisticated security fence, our bodies have evolved a barrier that protects the brain from potentially harmful substances in the blood but still allows the entry of essential molecules like blood sugar and oxygen.