Weather Averages for Cities in California. Select a link for the average weather, by month or year, in cities throughout California. The links take you to data for normal temperatures, precipitation, sunshine and humidity. Farther down the page you'll find links to in-depth weather information for Los Angeles, San Diego, San Francisco and many other places in the state. Temperature.
Vaginal intraepithelial neoplasia (VAIN) is a condition that describes premalignant histological findings in the vagina characterized by dysplastic changes. The disorder is rare and generally has no symptoms. VAIN can be detected by the presence of abnormal cells in a Papanicolaou test (Pap smear). Like cervical intraepithelial neoplasia, VAIN comes in three stages, VAIN 1, 2, and 3. In VAIN 1, a third of the thickness of the cells in the vaginal skin are abnormal, while in VAIN 3, the full thickness is affected. VAIN 3 is also known as carcinoma in-situ, or stage 0 vaginal cancer. Infection with certain types of the human papillomavirus (high-risk types) may be associated with up to 80% of cases of VAIN. Vaccinating girls with HPV vaccine before initial sexual contact has been shown to reduce incidence of VAIN.
Full Definition of HOPELESS. 1. a: having no expectation of good or success: despairing b: not susceptible to remedy or cure c: incapable of redemption or improvement. 2.