What is the definition of a dominant trait in biology? What is the difference between biology and AP biology? What is the difference between molecular biology and cell biology?
DNA gyrase, often referred to simply as gyrase, is an enzyme that relieves strain while double-strand DNA is being unwound by helicase. It is also known as DNA topoisomerase II. This causes negative supercoiling of the DNA. Bacterial DNA gyrase is the target of many antibiotics, including nalidixic acid, novobiocin, and ciprofloxacin.
Some characteristic mechanisms and reactions that DNA gyrase can undergo are: 1  ATP-dependent negative supercoiling of closed-circular double-stranded DNA. 2  ATP-independent relaxation of negatively supercoiled DNA. 3  Nucleotide-dependent relaxation of positively supercoiled DNA. 4  Formation and resolution of catenated DNA. 5  Resolution of knotted DNA.