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As in the arteries, the walls of veins have three layers, or coats: an inner layer, or tunica intima; a middle layer, or tunica media; and an outer layer, or tunica adventitia. Each coat has a number of sublayers.
Varicose veins may be more common in some families (inherited). Increased pressure in the veins may cause varicose veins. Deep vein thrombosis (DVT) is a serious condition with blood clots in the deep veins. This condition does not usually occur with varicose veins. That is because varicose veins affect the veins close to the surface of the skin.