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A lack of appetite is usually one of the earliest signs that your dog might be pregnant. Not all females go through this doggie version of morning sickness, but a small percentage of dogs will eat less during the first few weeks of gestation and will usually make up for it later in the pregnancy.
Remember that the first stage in the pregnancy of your dog will be the gestation. There are no clear symptoms to diagnose pregnancy in dog right after it happens. Thus, a dog is likely to show signs of pregnancy only after the first 25 to 36 days since mating.