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The most common and less serious side effects of metformin are bloating, gas, stomach pain, weakness, diarrhea, constipation, heartburn, sneezing, headaches, cough, flushing of the skin, vomiting, runny nose, nausea and muscle pain.
Unfortunately, the side effects of Metformin may require twice a day dosing to decrease the incidence and the severity of side effects. The side effects for Metformin include abdominal cramping, abdominal pain, nausea, vomiting, gas, and diarrhea.