This is at least 100-fold less than the level of residual plasmid DNA (1.2â6.3 % of the total rAAV vg) reported by Chadeuf et al. , and, when expressed as ng of residual DNA per 1 Ã 10 12 vg of rAAV, is comparable with the lowest amount of residual plasmid DNA reported by Hauck et al. (10 ng vs 8.6 ng).
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