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Answer Wiki. Anxiety, depression and paranoia go hand in hand. Depression and a negative outlook might cause anxiety, and that anxiety could cause paranoia, resulting in a cycle of self-deception, increasing intensity of fears and causing a lack of positive or any emotions.
Causes of paranoia. Researchers do not understand fully what chemical or physical changes in the brain cause paranoia. Paranoia is a prominent symptom that occurs in a variety of different mental disorders, as well as a symptom of certain physical diseases.Furthermore, use of certain drugs or chemicals may cause symptoms of paranoia in an otherwise normal individual.aranoia is a prominent symptom that occurs in a variety of different mental disorders, as well as a symptom of certain physical diseases. Furthermore, use of certain drugs or chemicals may cause symptoms of paranoia in an otherwise normal individual.