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The function of the immunological barrier in the epididymis is to protect the sperm from attack by the immune system. Primarily, this function is carried out by the BEB, which sequesters sperm antigens and restricts entry of immunoglobulins and immune cells (Fig. 2 B).
blood-brain barrier, n barrier formed by epithelial cells in the capillaries that supply the brain and central nervous system. This barrier selectively allows entry of substances such as glucose, some ions, and oxygen, while blocking entry of other substances.he blood-brain barrier prevents or slows the passage of some drugs and other chemical compounds, radioactive ions, and disease-causing organisms such as viruses from the blood into the central nervous system.