Inflammation and degradation of bone are two closely linked processes. Chronic inflammatory arthritis not only leads to inflammatory bone loss but it also involves local erosion of articular bone. This osteo-destructive feature of chronic inflammatory arthritis is a major cause of disability in patients with rheumatoid arthritis.
[ËÄ§alab]) is the largest city in Syria and serves as the capital of the Aleppo Governorate, the most populous Syrian governorate. With an official population of 2,132,100 (2004 census), it is also one of the largest cities in the Levant.
The Syrian Civil War is an ongoing international armed conflict taking place in Syria. The unrest began in the early spring of 2011 within the context of Arab Spring protests, with nationwide protests against President Bashar al-Assad 's government, whose forces responded with violent crackdowns.