Antibiotics effective against procaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum . If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum.
Sofia: Annual Weather Averages. July is the hottest month in Sofia with an average temperature of 21Â°C (70Â°F) and the coldest is January at -1Â°C (30Â°F) with the most daily sunshine hours at 10 in July. The wettest month is April with an average of 70mm of rain. Average Temperature: Sofia. Loading weather data.
Sofia is a young girl with shoulder-length wavy auburn hair. She has fair skin with rosy cheeks and large light blue eyes. Sofia's prominent princess gown has a lilac color and comes with a crystal tiara inset with diamonds and pearls, which also decorate her dress, and purple slippers with heels. Around her neck, she wears the royal family's amulet called the Amulet of Avalor.