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As in the arteries, the walls of veins have three layers, or coats: an inner layer, or tunica intima; a middle layer, or tunica media; and an outer layer, or tunica adventitia. Each coat has a number of sublayers.
Spider veins and varicose veins are common conditions that affect many adults. These abnormally enlarged vessels, which affect women more often than men, appear most often on the legs and become more prevalent with age. Spider veins and varicose veins affect up to 50% of the adult population.