Antibiotics effective against procaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum . If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum.
Sofia: Annual Weather Averages. July is the hottest month in Sofia with an average temperature of 21Â°C (70Â°F) and the coldest is January at -1Â°C (30Â°F) with the most daily sunshine hours at 10 in July. The wettest month is April with an average of 70mm of rain. Average Temperature: Sofia. Loading weather data.
Location of Sofia on a map. Sofia is a city found in Sofia-Capital, Bulgaria. It is located 42.70 latitude and 23.32 longitude and it is situated at elevation 562 meters above sea level. Sofia has a population of 1,152,556 making it the biggest city in Sofia-Capital. It operates on the CEST time zone.