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But when you stop using opiates abruptly, your body will react, leading to symptoms of withdrawal. Opiate withdrawal occurs in two phases. The first includes a number of symptoms, such as: 1  muscle aches. 2  restlessness. 3  anxiety. 4  tearing eyes. 5  runny nose. 6  excessive sweating.
Most addicts experience 3 phases of withdrawal while detoxing from opiates. During Phase 1, also known as acute withdrawal, symptoms begin about 12 hours after your last opiate use (or within 30 hours of the last methadone dose), peak around the 3-day mark, and last for approximately 5 days total.hat to Expect: An Opiate Withdrawal Timeline. By the time some people realize that they have to stop using opiates and drugs altogether, its clear to them that withdrawal is going to be excruciating because theyâve already experienced the pain of going a day or two without their pills.