I have a '5 Way Reflector' that I want to use in my photography, which includes the following 5 options: 1  Gold reflective. 2  Silver reflective. 3  Gold/silver alternating pattern reflective. 4  White. 5  Scrim/opaque. 6  Black*.
The endoplasmic reticulum (ER) resident PKR-like kinase (PERK) is necessary for Akt activation in response to ER stress. We demonstrate that PERK harbors intrinsic lipid kinase, favoring diacylglycerol (DAG) as a substrate and generating phosphatidic acid (PA). This activity of PERK correlates with activation of mTOR and phosphorylation of Akt on Ser473. PERK lipid kinase activity is regulated in a phosphatidylinositol 3-kinase (PI3K) p85Î±-dependent manner. Moreover, PERK activity is essential during adipocyte differentiation.
Note that the hinge exposure is independent of the active state of the kinase, reflecting rather the ``membrane-bound conformation'' of the enzyme (67) . Figure 3: Model for the regulation of protein kinase C by 1) phosphorylation and 2) membrane binding and pseudosubstrate release. Newly synthesized protein kinase C (PKC) associates with the detergent-insoluble fraction of cells (72) (bottom left).