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[4,5] The accelerated vaccination schedule for monovalent hepatitis B vaccine, administered on days 0, 7 and 21, rapidly induces long-lasting (>12 months) hepatitis B antibodies (anti-HBs) and high rates of seroprotection.
It is given in a series of 3 injections on the same schedule as the hepatitis B vaccine: an initial dose followed by doses at 1 month and 6 months. It can also be given in 4 doses, with the initial dose followed by doses at 7 days, 21 to 30 days, and 12 months.