Inflammation and degradation of bone are two closely linked processes. Chronic inflammatory arthritis not only leads to inflammatory bone loss but it also involves local erosion of articular bone. This osteo-destructive feature of chronic inflammatory arthritis is a major cause of disability in patients with rheumatoid arthritis.
[ËÄ§alab]) is the largest city in Syria and serves as the capital of the Aleppo Governorate, the most populous Syrian governorate. With an official population of 2,132,100 (2004 census), it is also one of the largest cities in the Levant.
Aleppo: Who controls what. Aleppo, once Syria's largest city, is an important battleground in the war with at least 250,000 besieged in the east. Aleppo is one of the key battlegrounds in the Syrian war. Since that conflict started in 2011, the northern city has been the stage of hard-fought battles. At least four major factions keep fighting for control of the strategically important city, which has seen some of the worst violence of the conflict.