What is the definition of a dominant trait in biology? What is the difference between biology and AP biology? What is the difference between molecular biology and cell biology?
DNA gyrase, often referred to simply as gyrase, is an enzyme that relieves strain while double-strand DNA is being unwound by helicase. It is also known as DNA topoisomerase II. This causes negative supercoiling of the DNA. Bacterial DNA gyrase is the target of many antibiotics, including nalidixic acid, novobiocin, and ciprofloxacin.
DNA gyrase is an important enzyme found in species that have circular strands of DNA. 1  When the helicase enzyme separates the annealed DNA helix, due to the cyclic nature of the DNA, supercoiling occurs (stressed, âoverâ coiling of the DNA strands).