Tofranil (imipramine): 1  Is generally used in children older than 6 years. 2  Has a success rate of 10 to 50 percent. 3  Starts working in a few days. 4  Is relatively inexpensive. 5  Will likely stop working when the child stops taking the medication.
The peak pressure is the pressure measured by the ventilator in the major airways, and it strongly reflects airways resistance. For example, in acute severe asthma, there is a large gradient between the peak pressure (high) and the plateau pressure (normal). In pressure controlled ventilation, the pressure limit is (usually) the plateau pressure due to the dispersion of gas in inspiration.
believe the answer you're looking for has to do with the pressure-altitude-voltage derating related to corona discharge, which increases (gets worse) with higher altitude and peaks at around 80-100,000' Typically this is considered to occur at votlages above 300 V peak, but be sure you are accounting for all transients and internal voltages.