Certain sub-stances in grapefruit juice block the action of CYP3A4, so instead of being metabolized, more of the drug enters the bloodstream and stays in the body longer. The result: potentially dangerous levels of the drug in your body. The amount of the CYP3A4 enzyme in the intestine varies from one per-son to another, says Huang. Some people have a lot, and others have just a littleâso grapefruit juice may affect people differently when they take the same drug.
3. Splitting Fruit. Like the foliage thatâs dying back, splitting tomato fruit is a sign of uneven watering. As the fruit is ripening if the plant receives too much water the skin will split because the fruitâs skin can no longer expand.
Q. I have 4'x 8' raised beds in my garden. My peppers, squash, and beans grow well, but my tomatoes have a horrible disease. The leaves get spotty, turn yellow, and eventually fall off. The fruits do fine, but the vines look horrible. Through the help of garden books, I think it's Verticillium Wilt, Fusarium Wilt, or Septoria Leaf Spot.