During this handshake, the client and server agree on various parameters used to establish the connection's security: 1  The handshake begins when a client connects to a TLS-enabled server requesting a secure connection and the client presents a list of supported cipher suites (ciphers and hash functions).
Allele frequency. Allele frequency is a term of population genetics that is used in characterizing the genetic diversity of a species population, or equivalently the richness of its gene pool.
An allele frequency is calculated by dividing the number of times the allele of interest is observed in a population by the total number of copies of all the alleles at that particular genetic locus in the population.Allele frequencies can be represented as a decimal, a percentage, or a fraction.In a population, allele frequencies are a reflection of genetic diversity. Changes in allele frequencies over time can indicate that genetic drift is occurring or that new mutations have been introduced into the population.llele frequencies can be represented as a decimal, a percentage, or a fraction. In a population, allele frequencies are a reflection of genetic diversity. Changes in allele frequencies over time can indicate that genetic drift is occurring or that new mutations have been introduced into the population.