Indirect Cost: Definition and Example. To facilitate preparation of an indirect cost proposal, shown below are (1) some definitions of the term indirect costs, (2) a brief discussion of indirect cost rate structures and (3) a simple example of an indirect cost rate computation.
Chancre: The classic painless ulcer of syphilis. The chancre forms in the first (primary) stage of syphilis. It is highly contagious and can last 1-5 weeks. The disease can be transmitted from contact with the ulcer, which is teeming with spirochetes. If the ulcer is outside of the vagina or on the scrotum of the male, the use of condoms may not help in preventing transmission of the disease.
During the primary stage, a sore (chancre) that is usually painless develops at the site where the bacteria entered the body. This commonly occurs within 3 weeks of exposure but can range from 10 to 90 days. A person is highly contagious during the primary stage. 1  In men, a chancre often appears in the genital area, usually (but not always) on the penis. 2  In women, chancres can develop on the outer genitals or on the inner part of the vagina.  Swelling of the lymph nodes may occur near the area of the chancre.