Inflammation and degradation of bone are two closely linked processes. Chronic inflammatory arthritis not only leads to inflammatory bone loss but it also involves local erosion of articular bone. This osteo-destructive feature of chronic inflammatory arthritis is a major cause of disability in patients with rheumatoid arthritis.
[ËÄ§alab]) is the largest city in Syria and serves as the capital of the Aleppo Governorate, the most populous Syrian governorate. With an official population of 2,132,100 (2004 census), it is also one of the largest cities in the Levant.
There were large communities in Aleppo (Halabi Jews, Aleppo is Halab in Arabic) and Damascus (Shami Jews) for centuries, and a smaller community in Qamishli on the Turkish border near Nusaybin. In the first half of the 20th century a large percentage of Syrian Jews immigrated to the U.S., Latin America and Israel.