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Stomach upset - Aspirin can upset a dog's stomach, which can interfere with the ultimate goal of relieving your dog's pain if he throws up the medication. Buffered aspirin is usually easier on a dog's stomach than non-buffered aspirin, especially if your vet advises you to give repeated doses.
For a 60lb dog, use 1 aspirin tablet (320 mg) or or 4 baby aspirins every 12 hours, if needed. If 1/2 a tablet works, it's alway better to use less, if you can get away with iâ¦t. Give the aspirin dose with food. Use buffered aspirin, or regular (non-coated) aspirin only.