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The most common and less serious side effects of metformin are bloating, gas, stomach pain, weakness, diarrhea, constipation, heartburn, sneezing, headaches, cough, flushing of the skin, vomiting, runny nose, nausea and muscle pain.
Lactic Acidosis. Metformin may cause lactic acidosis, which is a condition caused by excessive buildup of lactic acid in the body. Symptoms of lactic acidosis include weakness, drowsiness, decreased heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, lightheadedness and fainting.