Antibiotics effective against procaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum . If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum.
Sofia: Annual Weather Averages. July is the hottest month in Sofia with an average temperature of 21Â°C (70Â°F) and the coldest is January at -1Â°C (30Â°F) with the most daily sunshine hours at 10 in July. The wettest month is April with an average of 70mm of rain. Average Temperature: Sofia. Loading weather data.
Location: 101, Stamboliyski Blvd. City Center Sofia is a shopping mall situated to the south of the National Palace of Culture in the municipality of Triaditsa at the intersection of the Boulevards Cherni vrah and Arsenalski, diagonally opposed to the Hemus Hotel. It opened in the spring of 2006.