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The most common and less serious side effects of metformin are bloating, gas, stomach pain, weakness, diarrhea, constipation, heartburn, sneezing, headaches, cough, flushing of the skin, vomiting, runny nose, nausea and muscle pain.
In addition, taking metformin in the long run can lead to kidney failure, digestive disease, diarrhea, etc.so, despite of no kidney problems, patients with diabetes should not rely on metformin in the long term. As a consequent, we can know that metformin has side effects on kidney, doing harm to kidney function.