What is DUEXIS Â® (ibuprofen and famotidine)? DUEXIS contains two medicines: ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and famotidine, a histamine H 2-receptor antagonist.
Various factors contribute to foot and ankle swelling during pregnancy. For starters, your body retains more fluid during pregnancy. Also, your growing uterus puts pressure on your veins, which impairs return of blood to your heart. This can lead to swelling in the legs, ankles and feet.
Swollen ankles occur when fluid is retained in the spaces between our cells. This fluid buildup can have a number of different causes, most notably insufficiency of the venus system, water retention secondary to heart, kidney, liver, or endocrine disease, as well as local musculoskeletal issues such as trauma, infections, or tumors. All of these can cause swollen ankles. Pregnant women deal with swollen ankles on a daily basis due to weight gain and water retention. Waiters and waitresses also deal with swollen ankles after standing and walking for long periods.