1 Distance between North Carolina, NC and cities in North Carolina. 2  Distance between North Dakota, ND and cities in North Dakota. 3  Distance between Ohio, OH and cities in Ohio.
HER2 is a proto-oncogene that encodes an 185 k Datrans membrane receptor tyrosine kinase which exhibits extensive homology to epidermal growth factor receptor (EGFR) .HER2 is also known as the neu and cerbB2 proto-oncogene.ER2 is a proto-oncogene that encodes an 185 k Datrans membrane receptor tyrosine kinase which exhibits extensive homology to epidermal growth factor receptor (EGFR) .
BRCA2 and the link to homologous recombination. Affected individuals with mutation in the BRCA2 gene have a dominant heritable predisposition to breast, ovarian and other types of cancers. Tumorigenesis is associated with loss of heterozygosity of the non-mutated allele.bstract. BRCA2 is the product of a breast cancer susceptibility gene in humans and the founding member of an emerging family of proteins present throughout the eukaryotic domain that serve in homologous recombination.