What is DUEXIS Â® (ibuprofen and famotidine)? DUEXIS contains two medicines: ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and famotidine, a histamine H 2-receptor antagonist.
Various factors contribute to foot and ankle swelling during pregnancy. For starters, your body retains more fluid during pregnancy. Also, your growing uterus puts pressure on your veins, which impairs return of blood to your heart. This can lead to swelling in the legs, ankles and feet.
Swelling is most likely to be noticeable in your face, hands, or feet. As your pregnancy progresses, your uterus puts pressure on the circulation to your legs and may cause swelling in your feet and ankles.