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A Barr body is the inactivated X chromosome that is usually found in the nuclei of female somatic cells. It can also occur in males when there is an abnormality and the male is XXY instead of the normal XY, a condition known as Klinefelter's syndrome.
A Barr body (named after discoverer Murray Barr) is the inactive X chromosome in a female somatic cell, rendered inactive in a process called lyonization, in those species in which sex is determined by the presence of the Y (including humans) or W chromosome rather than the diploidy of the X or Z. typical human female has only one Barr body per somatic cell, while a typical human male has none. Mammalian X-chromosome inactivation is initiated from the X inactivation centre or Xic, usually found near the centromere.