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Definition of span. 1  1 : the distance from the end of the thumb to the end of the little finger of a spread hand; also : an English unit of length equal to nine inches (22.9 centimeters)
8. to extend or reach over or across (space or time). 9. to provide with something that extends over or across: to span a river with a bridge. 10. to measure by the hand with the thumb and little finger extended. 11. to encircle with the hand or hands.