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The most common and less serious side effects of metformin are bloating, gas, stomach pain, weakness, diarrhea, constipation, heartburn, sneezing, headaches, cough, flushing of the skin, vomiting, runny nose, nausea and muscle pain.
Metformin side effects. Get emergency medical help if you have signs of an allergic reaction to metformin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Some people develop lactic acidosis while taking metformin. Early symptoms may get worse over time and this condition can be fatal.