Inflammation and degradation of bone are two closely linked processes. Chronic inflammatory arthritis not only leads to inflammatory bone loss but it also involves local erosion of articular bone. This osteo-destructive feature of chronic inflammatory arthritis is a major cause of disability in patients with rheumatoid arthritis.
[ËÄ§alab]) is the largest city in Syria and serves as the capital of the Aleppo Governorate, the most populous Syrian governorate. With an official population of 2,132,100 (2004 census), it is also one of the largest cities in the Levant.
More than four million refugees of the Syrian Civil War have left the country during the course of the war. Most of them fled to neighboring Turkey, Lebanon, Jordan, and Iraq, while thousands also ended up in more distant countries of the Caucasus, the Persian Gulf, North Africa and Europe.