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1 Anxiety: An initial dose of 0.25 mg to 0.5 mg of Xanax is administered orally, three times a day. 2  The dose can be increased gradually every three to four days up to maximum daily dose of 4 mg in divided doses.3  Panic: An initial dose of 0.5 mg of Xanax is administered orally, three times a day. Depression: An initial dose of 0.5 mg of Xanax is administered orally three times a day. 2  The dose can be increased by no more than 1 mg every three to four days. 3  An average dose of 3 mg of Xanax daily in divided doses has shown to be most effective.
Panic Disorder. The successful treatment of many panic disorder patients has required the use of XANAX at doses greater than 4 mg daily. In controlled trials conducted to establish the efficacy of XANAX in panic disorder, doses in the range of 1 to 10 mg daily were used.The mean dosage employed was approximately 5 to 6 mg daily.Among the approximately 1700 patients participating in the panic disorder development program, about 300 received XANAX in dosages of greater than 7 mg/day, including approximately 100 patients who received maximum dosages of greater than 9 mg/day.anic Disorder. The successful treatment of many panic disorder patients has required the use of XANAX at doses greater than 4 mg daily. In controlled trials conducted to establish the efficacy of XANAX in panic disorder, doses in the range of 1 to 10 mg daily were used.