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But when you stop using opiates abruptly, your body will react, leading to symptoms of withdrawal. Opiate withdrawal occurs in two phases. The first includes a number of symptoms, such as: 1  muscle aches. 2  restlessness. 3  anxiety. 4  tearing eyes. 5  runny nose. 6  excessive sweating.
Early stage â The first symptoms of opiate withdrawal typically begin within eight to sixteen hours of the last use, but may take as long as thirty hours to occur depending on the opiate involved. Symptoms are initially mild but rapidly increase in severity.