Certain sub-stances in grapefruit juice block the action of CYP3A4, so instead of being metabolized, more of the drug enters the bloodstream and stays in the body longer. The result: potentially dangerous levels of the drug in your body. The amount of the CYP3A4 enzyme in the intestine varies from one per-son to another, says Huang. Some people have a lot, and others have just a littleâso grapefruit juice may affect people differently when they take the same drug.
3. Splitting Fruit. Like the foliage thatâs dying back, splitting tomato fruit is a sign of uneven watering. As the fruit is ripening if the plant receives too much water the skin will split because the fruitâs skin can no longer expand.
Your tomato plant could have blightâ¦. The other option is, as the indeterminate plant grows it produces from the âground upâ. Tomato plants grown in controlled environments, such as a greenhouse, are usually kept producing for two years. The grower keeps the plant growing on a string up and will ârollâ the plant down.