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Stomach upset - Aspirin can upset a dog's stomach, which can interfere with the ultimate goal of relieving your dog's pain if he throws up the medication. Buffered aspirin is usually easier on a dog's stomach than non-buffered aspirin, especially if your vet advises you to give repeated doses.
That said, this type of aspirin can be carefully given to dogs to help with short-term pain. Itâs acceptable but the risks are somewhat higher for pets. Baby aspirin in particular, on a short term basis only, is okay but longer term canine use is more dangerous.