Certain sub-stances in grapefruit juice block the action of CYP3A4, so instead of being metabolized, more of the drug enters the bloodstream and stays in the body longer. The result: potentially dangerous levels of the drug in your body. The amount of the CYP3A4 enzyme in the intestine varies from one per-son to another, says Huang. Some people have a lot, and others have just a littleâso grapefruit juice may affect people differently when they take the same drug.
3. Splitting Fruit. Like the foliage thatâs dying back, splitting tomato fruit is a sign of uneven watering. As the fruit is ripening if the plant receives too much water the skin will split because the fruitâs skin can no longer expand.
Water. A lack of water may be causing your tomato plants to wilt. Tomato plants need approximately 1 inch of water each week to remain healthy. If your plants perk up after watering, a lack of moisture in the soil could be the cause of the wilt. Over-watering your tomato plants may also cause wilt. Tomatoes react badly to wet feet, a condition that refers to their roots being trapped in wet soil for extended periods of time.