What is DUEXIS Â® (ibuprofen and famotidine)? DUEXIS contains two medicines: ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and famotidine, a histamine H 2-receptor antagonist.
Various factors contribute to foot and ankle swelling during pregnancy. For starters, your body retains more fluid during pregnancy. Also, your growing uterus puts pressure on your veins, which impairs return of blood to your heart. This can lead to swelling in the legs, ankles and feet.
A bandage may help if ankle swelling is due to an injury. Photo Credit abdone/iStock/Getty Images. Swollen ankles are common during pregnancy or immediately following an injury, but if your ankles are swelling mainly at night, you may have an underlying medical condition.