Antibiotics effective against procaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum . If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum.
Sofia: Annual Weather Averages. July is the hottest month in Sofia with an average temperature of 21Â°C (70Â°F) and the coldest is January at -1Â°C (30Â°F) with the most daily sunshine hours at 10 in July. The wettest month is April with an average of 70mm of rain. Average Temperature: Sofia. Loading weather data.
Sofia Vergara's Wedding Photos From When She Was 18 are as Glorious and Gorgeous as You'd Imagine: See Them Here! Sofia Vergara, 18, on her wedding day in Barranquilla, Colombia in 1991. Here comes the brideâthe first time! Sofia Vergara, 42, may be heading down the aisle again soonâthis time, to wed her hunk of a fiancÃ©, Joe Manganiello.