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Stomach upset - Aspirin can upset a dog's stomach, which can interfere with the ultimate goal of relieving your dog's pain if he throws up the medication. Buffered aspirin is usually easier on a dog's stomach than non-buffered aspirin, especially if your vet advises you to give repeated doses.
Aspirin can be used to treat dogs that are in pain. However, it's important to understand the correct dosage for your individual dog, as well as the possible side-effects it can have on your pet, before you give it to him.