During this handshake, the client and server agree on various parameters used to establish the connection's security: 1  The handshake begins when a client connects to a TLS-enabled server requesting a secure connection and the client presents a list of supported cipher suites (ciphers and hash functions).
Allele frequency. Allele frequency is a term of population genetics that is used in characterizing the genetic diversity of a species population, or equivalently the richness of its gene pool.
The frequency of an allele within the gene pool is an important measure of evolution. Favorable mutations (variant alleles) will increase their frequency in the gene pool, while detrimental mutations will decrease their frequency.