Indirect Cost: Definition and Example. To facilitate preparation of an indirect cost proposal, shown below are (1) some definitions of the term indirect costs, (2) a brief discussion of indirect cost rate structures and (3) a simple example of an indirect cost rate computation.
Chancre: The classic painless ulcer of syphilis. The chancre forms in the first (primary) stage of syphilis. It is highly contagious and can last 1-5 weeks. The disease can be transmitted from contact with the ulcer, which is teeming with spirochetes. If the ulcer is outside of the vagina or on the scrotum of the male, the use of condoms may not help in preventing transmission of the disease.
This stage typically starts with the development of a rash on one or more areas of the body. Rashes associated with secondary syphilis can appear when the primary chancre is healing or several weeks after the chancre has healed. The rash usually does not cause itching.t appears at the location where syphilis entered the body. These painless chancres can occur in locations that make them difficult to find (e.g., the vagina or anus). The chancre lasts 3 to 6 weeks and heals regardless of whether a person is treated or not.