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The function of the immunological barrier in the epididymis is to protect the sperm from attack by the immune system. Primarily, this function is carried out by the BEB, which sequesters sperm antigens and restricts entry of immunoglobulins and immune cells (Fig. 2 B).
Presentation Transcript. blood-testis barrier: blood-testis barrier The blood-testis barrier (BTB) is a physical barrier between the blood or lymph vessels and the lumen of seminiferous tubules of the animal testes.lood-testis barrier: HOW IT FORM Myoid layer Sertoli cell junction Sertoli cell junction formed by tight connections between the Sertoli cells, which are sustentacular cells (nurse cells) of the seminiferous tubules, and nourish the spermatogonia.