What is the definition of a dominant trait in biology? What is the difference between biology and AP biology? What is the difference between molecular biology and cell biology?
DNA gyrase, often referred to simply as gyrase, is an enzyme that relieves strain while double-strand DNA is being unwound by helicase. It is also known as DNA topoisomerase II. This causes negative supercoiling of the DNA. Bacterial DNA gyrase is the target of many antibiotics, including nalidixic acid, novobiocin, and ciprofloxacin.
DNA gyrase has two subunits, which in turn have two subunits each, i.e. 2A and 2B SUBUNITS. The A and B subunits together bind to DNA, hydrolyze ATP, and introduce negative supertwists.The A subunit carries out nicking of DNA, B subunit introduces negative supercoils, and then A subunit reseals the strands.t is also known as DNA topoisomerase II. This causes negative supercoiling of the DNA. Bacterial DNA gyrase is the target of many antibiotics, including nalidixic acid, novobiocin, and ciprofloxacin.