Tofranil (imipramine): 1  Is generally used in children older than 6 years. 2  Has a success rate of 10 to 50 percent. 3  Starts working in a few days. 4  Is relatively inexpensive. 5  Will likely stop working when the child stops taking the medication.
The plateau pressure is the pressure applied (in positive pressure ventilation) to the small airways and alveoli. It is believed that control of the plateau pressure is important, as excessive stretch of alveoli has been implicated as the cause of ventilator induced lung injury.
Answer and interpretation. To prevent lung injury, alveolar pressure (aka the plateau pressure) should be kept <30 cmH2O. High alveolar pressures can be due to excessive tidal volume, gas trapping, PEEP or low compliance as shown by this relationship: alveolar pressure = (volume/ compliance) + PEEP.