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Intrinsic factor. Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine. In humans, the gastric intrinsic factor protein is encoded by the GIF gene.
factor XIII, one of the blood clotting factors that converts soluble fibrin monomer to insoluble, stable fibrin polymer. intrinsic factor. a glycoprotein secreted by the parietal cells of the gastric glands, necessary for the absorption of vitamin B 12 (cyanocobalamin, extrinsic factor).Its absence in humans results in pernicious anemia. factor that, when activated, serves as a serine esterase in the alternate complement pathway. extrinsic factor. a hematopoietic vitamin that combines with intrinsic factor for absorption from the intestine and is needed for erythrocyte maturation; called also cyanocobalamin and vitamin B 12.