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Necrotizing enterocolitis (NEC) is a serious intestinal illness in babies. Necrotizing means damage and death of cells. Entero refers to the intestine. Colitis means inflammation of the colon (lower part of the intestine). Although NEC may develop in any newborn, most cases occur in premature babies and in up to 5 percent of babies in newborn intensive care units.
Necrotizing Enterocolitis Involves Infection of the Intestines. Preemies. Necrotizing enterocolitis, usually called NEC, is a condition where the intestines become infected and can begin to die. The disease usually affects premature babies, although term babies may also get NEC. Necrotizing enterocolitis is a serious condition that may require surgery, and has a high morbidity and mortality rate.