Antibiotics effective against procaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum . If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum.
Sofia: Annual Weather Averages. July is the hottest month in Sofia with an average temperature of 21Â°C (70Â°F) and the coldest is January at -1Â°C (30Â°F) with the most daily sunshine hours at 10 in July. The wettest month is April with an average of 70mm of rain. Average Temperature: Sofia. Loading weather data.
Time difference between New York, USA and Sofia, Bulgaria is: +7:0 hours. Sofia is 7:0 hours ahead of New York. That means when it is 8:00 am in New York, it is 3:00 pm in Sofia. Daylight Saving Time (DST) / Summer Time is taken into account for all time difference calculations on this page.