Inflammation and degradation of bone are two closely linked processes. Chronic inflammatory arthritis not only leads to inflammatory bone loss but it also involves local erosion of articular bone. This osteo-destructive feature of chronic inflammatory arthritis is a major cause of disability in patients with rheumatoid arthritis.
[ËÄ§alab]) is the largest city in Syria and serves as the capital of the Aleppo Governorate, the most populous Syrian governorate. With an official population of 2,132,100 (2004 census), it is also one of the largest cities in the Levant.
Grafton had a population of almost 1,500 just before the American Civil War. The town suffered severe losses during the Civil War. Local cemeteries in the village hold many tombstones of casualties from the Battle of Gettysburg. After the war, the community declined in population.