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calcine (third-person singular simple present calcines, present participle calcining, simple past and past participle calcined) ( 1 transitive) to heat something without melting in order to drive off water etc., and to decompose carbonates into oxides or to oxidize or reduce it; especially to heat limestone to form quicklime.
1 - Colchicine is an alkaloid derived from the dried seeds of Colchicum autumnale, also known as the autumn crocus or meadow saffron. The use of the Colchicum alkaloid for the treatment of acute gout dates back to 1810. The medicinal value of colchicum was reported back in the first century A.D.