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The most common and less serious side effects of metformin are bloating, gas, stomach pain, weakness, diarrhea, constipation, heartburn, sneezing, headaches, cough, flushing of the skin, vomiting, runny nose, nausea and muscle pain.
Your doctor may need to change the doses of your medications or monitor you carefully for side effects. ... Metformin side effects can also affect other parts of the body. It can leave a metallic taste in the mouth, cause heartburn or headache, flushing of the skin, nail changes or muscle pain. More serious metformin side effects include chest pain or rash. ...