What is DUEXIS Â® (ibuprofen and famotidine)? DUEXIS contains two medicines: ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and famotidine, a histamine H 2-receptor antagonist.
Various factors contribute to foot and ankle swelling during pregnancy. For starters, your body retains more fluid during pregnancy. Also, your growing uterus puts pressure on your veins, which impairs return of blood to your heart. This can lead to swelling in the legs, ankles and feet.
Swelling (oedema) can happen in pregnancy because your body is holding on to more fluid than usual. Oedema can happen anywhere in the body, but it's particularly common in the legs, ankles, feet and hands. As your baby grows, your womb (uterus) puts pressure on the blood vessels in your pelvis.