Antibiotics effective against procaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum . If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum.
Sofia: Annual Weather Averages. July is the hottest month in Sofia with an average temperature of 21Â°C (70Â°F) and the coldest is January at -1Â°C (30Â°F) with the most daily sunshine hours at 10 in July. The wettest month is April with an average of 70mm of rain. Average Temperature: Sofia. Loading weather data.
Sofia (ÑÐ¾ÑÐ¸Ñ) is the capital of Bulgaria. It is also the biggest city in the country with about 1.4 million citizens (including suburbs). Today, Sofia is a dynamic Eastern European capital, distinguished by its unique combination of European and Communist-style architecture as well as many beautiful orthodox churches.