A debit card issued by or in conjunction with a certain company. For example, a retail shop may issue a proprietary debit card along with a bank.The use of a proprietary debit card may entitle one to discounts or other incentives to buy from the issuer (or co-issuer). debit card issued by or in conjunction with a certain company. For example, a retail shop may issue a proprietary debit card along with a bank. The use of a proprietary debit card may entitle one to discounts or other incentives to buy from the issuer (or co-issuer). 1  Facebook.
Rheumatoid arthritis is a chronic (long-lasting) inflammatory disease that causes pain, stiffness, warmth, redness and swelling in joints. Over time, the affected joints may become misshapen, misaligned and damaged.
However, many people with HLA-DR4 or HLA-DR1 do not get rheumatoid arthritis. Thus, your genes, HLA-DR4 or HLA-DR1 may increase the chances that you get rheumatoid arthritis, but they are not one of the causes of rheumatoid arthritis.