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Homozygous and Heterozygous. If an organism has two copies of the same allele, for example AA or aa, it is homozygous for that trait. If the organism has one copy of two different alleles, for example Aa, it is heterozygous. Keep in mind that an organism can't simply be 'homozygous,' period. For each of the organism's thousands of genes, it is either homozygous or heterozygous at that genetic locus.
A diploid organism is heterozygous at a gene locus when its cells contain two different alleles of a gene. The cell or organism is called a heterozygote specifically for the allele in question, therefore, heterozygosity refers to a specific genotype.f both alleles of a diploid organism are the same, the organism is homozygous at that locus. If they are different, the organism is heterozygous at that locus. If one allele is missing, it is hemizygous, and, if both alleles are missing, it is nullizygous.