What is the definition of a dominant trait in biology? What is the difference between biology and AP biology? What is the difference between molecular biology and cell biology?
DNA gyrase, often referred to simply as gyrase, is an enzyme that relieves strain while double-strand DNA is being unwound by helicase. It is also known as DNA topoisomerase II. This causes negative supercoiling of the DNA. Bacterial DNA gyrase is the target of many antibiotics, including nalidixic acid, novobiocin, and ciprofloxacin.
1 This guidance is intended to assist the pharmaceutical industry and other investigators engaged. in new drug development in evaluating how variations in the human genome, specifically DNA. sequence variants, could affect a drugâs pharmacokinetics (PK), pharmacodynamics (PD), efficacy, or safety.