Antibiotics effective against procaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum . If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum.
Sofia: Annual Weather Averages. July is the hottest month in Sofia with an average temperature of 21Â°C (70Â°F) and the coldest is January at -1Â°C (30Â°F) with the most daily sunshine hours at 10 in July. The wettest month is April with an average of 70mm of rain. Average Temperature: Sofia. Loading weather data.
Weather Overview for Sofia. 1  Sofiaâs climate is continental; it is cold and snowy in winter and hot and wet in summer. 2  Sofia is the historic capital of Bulgaria - one of the oldest cities in Europe. 3  Summer. While summers in Sofia can get very hot, it is in fact cooler than many other, lower lying, areas of Bulgaria.