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The most common and less serious side effects of metformin are bloating, gas, stomach pain, weakness, diarrhea, constipation, heartburn, sneezing, headaches, cough, flushing of the skin, vomiting, runny nose, nausea and muscle pain.
A large overdose of metformin may lead to lactic acidosis (with symptoms of deep and rapid breathing, vomiting, stomach pain, feeling of being very weak and unwell), which is a medical emergency and must be treated in hospital.