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1 Anxiety: An initial dose of 0.25 mg to 0.5 mg of Xanax is administered orally, three times a day. 2  The dose can be increased gradually every three to four days up to maximum daily dose of 4 mg in divided doses.3  Panic: An initial dose of 0.5 mg of Xanax is administered orally, three times a day. Depression: An initial dose of 0.5 mg of Xanax is administered orally three times a day. 2  The dose can be increased by no more than 1 mg every three to four days. 3  An average dose of 3 mg of Xanax daily in divided doses has shown to be most effective.
For elderly people or those with liver disease or other serious health problems, the recommended starting Xanax dose for anxiety is 0.25 mg two or three times daily. Higher dosages are often necessary to control the symptoms of panic disorder.s always, do not adjust your dose unless your healthcare provider specifically instructs you to do so. The recommended starting dose for treating anxiety is Xanax 0.25 mg to 0.5 mg three times daily.