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A Barr body is the inactivated X chromosome that is usually found in the nuclei of female somatic cells. It can also occur in males when there is an abnormality and the male is XXY instead of the normal XY, a condition known as Klinefelter's syndrome.
Medical Definition of BARR BODY. : a densely staining inactivated condensed X chromosome that is present in each somatic cell of most female mammals and is used as a test of genetic femaleness (as in a fetus or an athlete)âcalled also sex chromatin.efinition of BARR BODY. : a densely staining inactivated condensed X chromosome that is present in each somatic cell of most female mammals and is used as a test of genetic femaleness (as in a fetus) âcalled also sex chromatin. ADVERTISEMENT. Murray Llewellyn Barr â 1995 Canadian anatomist.