Tofranil (imipramine): 1  Is generally used in children older than 6 years. 2  Has a success rate of 10 to 50 percent. 3  Starts working in a few days. 4  Is relatively inexpensive. 5  Will likely stop working when the child stops taking the medication.
The plateau pressure is the pressure applied (in positive pressure ventilation) to the small airways and alveoli. It is believed that control of the plateau pressure is important, as excessive stretch of alveoli has been implicated as the cause of ventilator induced lung injury.
Based on work at Mayo Clinic, it now appears that the core pathogenic factor in SIH is decreased CSF volume rather than decreased CSF opening pressure. Patients can have normal CSF pressure and yet have this syndrome, Dr. Mokri says. Even orthostatic headache, the most common symptom of SIH, appears to vary.