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Necrotizing enterocolitis (NEC) is a serious intestinal illness in babies. Necrotizing means damage and death of cells. Entero refers to the intestine. Colitis means inflammation of the colon (lower part of the intestine). Although NEC may develop in any newborn, most cases occur in premature babies and in up to 5 percent of babies in newborn intensive care units.
Acute tubular necrosis (ATN) is the death of tubular cells, which may result when tubular cells do not get enough oxygen (ischemic ATN) or when they have been exposed to a toxic drug or molecule (nephrotoxic ATN). Fortunately, new tubular cells usually replace those that have died.