Certain sub-stances in grapefruit juice block the action of CYP3A4, so instead of being metabolized, more of the drug enters the bloodstream and stays in the body longer. The result: potentially dangerous levels of the drug in your body. The amount of the CYP3A4 enzyme in the intestine varies from one per-son to another, says Huang. Some people have a lot, and others have just a littleâso grapefruit juice may affect people differently when they take the same drug.
3. Splitting Fruit. Like the foliage thatâs dying back, splitting tomato fruit is a sign of uneven watering. As the fruit is ripening if the plant receives too much water the skin will split because the fruitâs skin can no longer expand.
The appearance of yellow leaves on your tomato plant is usually not a death sentence. However, it does mean that your plant has a problem in need of attention and correction. Tomatoes need nitrogen; their leaves will turn yellow without it. Mix some compost or used coffee grounds in with the soil to determine if a lack of nitrogen is the problem. If the bottom leaves of your tomato plant turn yellow, it's probably lacking in important nutrients. It may not be getting adequate sunlight.