Antibiotics effective against procaryotes which kill or inhibit a wide range of Gram-positive and Gram-negative bacteria are said to be broad spectrum . If effective mainly against Gram-positive or Gram-negative bacteria, they are narrow spectrum.
Sofia: Annual Weather Averages. July is the hottest month in Sofia with an average temperature of 21Â°C (70Â°F) and the coldest is January at -1Â°C (30Â°F) with the most daily sunshine hours at 10 in July. The wettest month is April with an average of 70mm of rain. Average Temperature: Sofia. Loading weather data.
Sofia the First is an American computer-animated television series that incorporates characters from the Disney Princess franchise. The series stars Ariel Winter as Sofia, a young girl who becomes a princess when her mother, Miranda, marries King Roland II of the kingdom of Enchancia.It features songs written by John Kavanaugh and Erica Rothschild and a musical score by Kevin Kliesch. Kate Higgins as Aurora from Sleeping Beauty-she teaches Sofia that in a crisis she can always count on her animal friends in episode 23 Holiday in Enchancia. 2  She is the first Disney Princess who doesn't sing in the series.