What is DUEXIS Â® (ibuprofen and famotidine)? DUEXIS contains two medicines: ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and famotidine, a histamine H 2-receptor antagonist.
Various factors contribute to foot and ankle swelling during pregnancy. For starters, your body retains more fluid during pregnancy. Also, your growing uterus puts pressure on your veins, which impairs return of blood to your heart. This can lead to swelling in the legs, ankles and feet.
This causes edema of the hands, face, legs, ankles and feet, and is a normal part of pregnancy Swelling can also be pronounced in the legs and feet because of the enlarged womb (uterus) taking up space in the abdomen and inhibiting return of fluids from the legs.