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1 A typical level of HDL-C is between 40-50 mg/dL (1.0-1.3 mmol/L) for men and between 50-59 mg/dl (1.3-1.5 mmol/L) for women and is associated with average risk of heart disease. 2  Based on many epidemiologic studies, HDL-C of 60 mg/dL (1.55 mmol/L) or higher is associated with a less than average risk of heart disease.
These guidelines can be used to determine healthy cholesterol ratios as well. For example, a patient with total cholesterol number 200, LDL number 100, and HDL number 60 has a Total/HDL cholesterol ratio of 200/60 and an LDL/HDL ratio of 100/60. This gives an optimal Total/HDL ratio of about 3.3:1 and an optimal LDL/HDL ratio of about 1.7:1.