They do this by causing cramping and contractions of the uterus. Often multiple doses over many hours are required to get the cervix ready for labor. Your baby is monitored for 1 to 12 hours after the use of the agents (the length of monitoring depends on the method used). If you are having contractions on your own, it may not be safe to use these medicines.
Biltmore Estate was chosen as one of several locations for this film. Hannibal cast and crew also filmed in the venerable Florence, Italy. The magnetic and horrifying character of Hannibal Lecter, played by Anthony Hopkins, resurfaces after his escape in Silence of the Lambs, the movie that precedes this.
List of most expensive films. Ben-Hur (1925) was the most expensive film of the silent-era, possibly holding the record for over twenty years. Due to the secretive nature of Hollywood accounting it is not clear which film is the most expensive film ever made. Pirates of the Caribbean: On Stranger Tides officially holds the record with a budget of $378.5 million, while The Hobbit trilogy stands as the most expensive back-to-back film production with combined costs of $623 million after tax credits.