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DRUG DESCRIPTION. WELLBUTRIN XLÂ® (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin reuptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines.
Doctors are warning that an antidepressant sold under such names as Wellbutrin, as well as a smoking cessation drug called Zyban, is increasingly being abused by drug users â with often fatal results. The drug is a medication called bupropion that has long been hailed as a wonder drug. Itâs an antidepressant that has been used at different strengths for years to helped thousands of Canadians battle mood disorders, depression, seasonal affective disorder and to quit smoking. Bupropion doesnât produce many of the side effects of other antidepressants and is considered non-habit-forming. But drug abusers have recently discovered that if the pills â particularly Wellbutrin -- are crushed and then snorted or injected, they produce a high similar to that from amphetamines or crack cocaine.