Biologics indicated for psoriasis work inside the body to target an overactive immune system, a possible cause of plaque psoriasis. When you talk to your dermatologist about plaque psoriasis treatment options, here are some things to think about: Once every 12 weeks (after 2 starter doses at weeks 0 and 4)
SKIP-BO(IPA: /skÉªpË-boÊ/) is a popular card game. In 1967, Ms. Hazel Bowman of Brownfield, Texas began producing a boxed edition of the game under the name Skip-bo. International Games, Inc. purchased the game in 1980. The company was subsequently bought by Mattel. It is a commercial version of the card-game Spite and Malice.
In the sport of curling, the skip is the captain of a team. The skip determines strategy, and holds the broom in the house to indicate where a teammate at the other end of the curling sheet should aim the stone. The skip usually throws the last two stones in the fourth position, but may play in any other position.