The Mediterranean Sea is a large sea that is located between Europe, northern Africa and southwestern Asia. Its total area is 970,000 square miles (2,500,000 sq km) and its greatest depth is located off the coast of Greece at around 16,800 feet (5,121 m) deep.
3. Inflammation of the nodes: buboes; Lymph nodes can become cancerous tissues and metastesize. Other Lymphoid Organs. Spleen: Filters and purifies lymph nodes. (macrophages and lymphocytes in spleen fights bacteria, toxins and viruses, removes cellular debris). Distributes and recycles aged RBC);.
Another function of macrophages involves the inflammatory response. After tissue has been injured, macrophages in the area will release chemicals that promote blood flow to the region and cause inflammation.