Drugs versus Biologics. 1  A biologic is manufactured in a living system such as a microorganism, or plant or animal cells. 2  Most biologics are very large, complex molecules or mixtures of molecules.enerics Drugs versus Follow-On Biologics. 1  To be approved as a generic, a drug must have the same active ingredient, strength, dosage form, and route of administration as the reference drug, and it must also be bioequivalent..
Acute watery diarrhea is most commonly seen with traveler's diarrhea caused by enterotoxigenic E. coli (ETEC), parasite-induced diarrhea from Giardia and Cryptosporidium spp. and, in cases of food poisoning (ingestion of preformed toxins), from B. cereus and S. aureus.
1 Chronic cases of infectious diarrhea may be seen in immunocompromised patients (as seen in HIV diarrhea) or associated with a Clostridium difficile infection (as seen in antibiotic-associated diarrhea).  Malabsorption syndromes are another common cause of watery stool or watery diarrhea. In these cases, there is failure of the small intestine to absorb nutrients, which is further compounded by decreased water absorption in the large intestine.