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Levothyroxine is the generic name for the synthetic form of thyroxine, a thyroid hormone replacement drug. This drug contains the synthetic form of one thyroid hormone, T4. Levothyroxine is the most commonly prescribed thyroid hormone replacement drug. Brand names in the U.S: Synthroid, Levothroid, Levoxyl, Unithroid.
Lithium is a medication used in the treatment for certain psychiatric disorders. However, lithium prevents thyroid hormone release and can cause hypothyroidism. The hypothyroidism is usually mild (subclinical). This typically happens within the first two years of starting lithium. Risk factors include female gender, elderly patients, and the presence of underlying autoimmune thyroiditis.