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Lipase is a digestive enzyme produced by the following organs: pancreas (pancreatic lipase), liver (hepatic lipase), and stomach (stomach/gastric lipase). Enzymes are responsible for the metabolism of carbohydrates, proteins, and fats.
Most lipid digestion takes place in the small intestine, but some gastric lipase is sectreted in the stomach and some lingual lipase is secreted in saliva and remains active in the low pH of the stomach. The most functionally important lipase is pancreatic lipase.