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The recommended starting dose of Zoloft for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is Zoloft 25 mg once a day.
Here, the medication doses were high. In adults, the standard Zoloft dose for depression is 50 mg daily. A number of patients in my practice have done well on 25 mg. To treat anxiety, the starting doses tend to be low; at first, antidepressants can increase anxiety.But for unknown reasons, the final dose, to mitigate anxiety, can be substantial.f we assume that Zoloft distributes throughout the body, the children were taking a Zoloft dose equivalent to over 250 mg daily for an adult. So what the study seems to show is that, in children, if you use medication to pound the hell out of anxiety, it remits.