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The recommended starting dose of Zoloft for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is Zoloft 25 mg once a day.
1 The medication comes in tablet and liquid form. You take Zoloft by mouth -- usually once a day.  Zoloft oral concentrate (the liquid form) must be diluted before each use. Measure the correct amount, then mix it with 4 ounces (half a cup) of water, ginger ale, lemon-lime soda, lemonade, or orange juice.