In which case, it depends on the type of inhibitor. A competitive inhibitor has a structure similar to the substrate, hence would bind to the active site as well, competing with the substrate for the enzyme active sites, decreasing enzymatic activity. A non-competitive inhibitor binds to the allosteric site of the enzyme, causing a structural change in the enzyme active site shape.
There's a difference between the effects of cold-brewed coffee vs. hot-brewed coffee: because different chemical reactions are achieved at higher temperatures, cold-brewed coffee will have a smoother caffeine effect and overall less acidity, which some people experience as part of the kick..
Coffee Allergy Symptoms. Coffee allergies are caused when you have an immune response to the protein that is found in it. After drinking coffee, you can end up with a collection of symptoms. The symptoms of a coffee allergy are similar to many other food allergies. Runny noses and watery eyes are often associated with a cold, but they are also symptoms of a coffee allergy.