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Medroxyprogesterone subcutaneous injection (depo-subQ Provera 104Â®) is a prescription medication approved to prevent pregnancy and to manage pain caused by endometriosis. This product contains medroxyprogesterone, a progestin hormone. It is given as a subcutaneous (below the skin) injection every three months.
This method of drug or fluid delivery reduces the risk of infection at the injection site and eliminates concerns about air emboli in the blood vessels. There are a number of subcutaneous infusion sites on the body which can be rotated to keep a patient more comfortable if long term therapy is being used. Patients and caregivers should be aware that some medications can cause skin irritation when they are infused subcutaneously.