The neuromuscular junction is the site of the signal exchange. The steps of this process in vertebrates occur as follows:(`) The action potential reaches the axon terminal. (2) Voltage-dependent calcium gates open, allowing calcium to enter the axon terminal.he neuromuscular junction is the site of the signal exchange. The steps of this process in vertebrates occur as follows:(`) The action potential reaches the axon terminal. (2) Voltage-dependent calcium gates open, allowing calcium to enter the axon terminal.
Sudden onset pain on the outer side of the foot can be from a fracture of the 5th Metatarsal and injuries to this bone are a common sports injury. Causes of pain on the outside of the foot are listed here: 1  Midtarsal Joint Sprain A mid tarsal joint sprain is an injury to the ligaments holding the mid tarsal joint together causing pain in the outside middle of the foot. 2  Peroneus Brevis Tendon Injury The Peroneus Brevis tendon inserts into the 5th matatarsal bone on the outside of the foot.
Sciatica is a condition caused by irritation of the sciatic nerve and you'll feel the effects as numbness in one leg or foot, a shooting pain down the back of one thigh or in your buttock, and pain in the leg when you sit, stand, strain, cough and sneeze.. Guillain-Barre Syndrome Can Cause Numb Legs. Guillain-Barre syndrome is a condition where your immune system attacks your own nerves. The condition causes weakness and tingling in your hands and feet, which spreads to the rest of the body including the legs.