Collagen is an important protein that can be found throughout your body. In fact, it is found in all the connective tissues in your body ranging from your skin and bones, all the way down to your organs and blood vessels. Collagen functions several different ways in your body.
Upper gastrointestinal bleeding. Upper gastrointestinal bleeding (sometimes upper GI, UGI bleed, Upper gastrointestinal hemorrhage, gastrorrhagia) is gastrointestinal bleeding in the upper gastrointestinal tract, commonly defined as bleeding arising from the esophagus, stomach, or duodenum. Blood may be observed in vomit (hematemesis) or in altered form in the stool (melena).
The goal of medical therapy in upper gastrointestinal bleeding (UGIB) is to correct shock and coagulation abnormalities and to stabilize the patient so that further evaluation and treatment can proceed. High doses may reduce the need for endoscopic therapy (see treatment with proton pump inhibitors).atients should be considered for upper endoscopy if blood loss from the upper gastrointestinal tract is suspected. The patient should undergo upper endoscopy prior to any operative intervention in order to diagnose and localize the bleeding site. Most patients (85-90%) respond to endoscopic therapy.