ESIM - Evaporative System Integrity Monitor, All Acronyms, viewed April 16, 2017, <https://www.allacronyms.com/ESIM/Evaporative_System_Integrity_Monitor>.
Acetylcholine is the neurotransmitter used at the neuromuscular junction âin other words, it is the chemical that motor neurons of the nervous system release in order to activate muscles.
When an action potential reaches the axon terminal of a motor neuron, vesicles carrying neurotransmitters (mostly acetylcholine) are exocytosed and the contents are released into the neuromuscular junction. These neurotransmitters bind to receptors on the postsynaptic membrane and lead to its depolarization.In the absence of an action potential, acetylcholine vesicles spontaneously leak into the neuromuscular junction and cause very small depolarizations in the postsynaptic membrane.hen an action potential causes the release of many acetylcholine vesicles, acetylcholine diffuses across the neuromuscular junction and binds to ligand gated nicotinic receptors (non-selective cation channels) on the muscle fiber.