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DRUG DESCRIPTION. WELLBUTRIN XLÂ® (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin reuptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines.
Bupropion is an atypical antidepressant that&#039;s sold as Wellbutrin and Wellbutrin XL. Desipramine--Norpramin--is an older antidepressant in the tricyclic group of antidepressants. Another tricyclic antidepressant, trazodone--. Desyrel--may also yield a false positive for amphetamines if you take this medication.ore sophisticated drug testing, as with one of the spectrometry methods, should reveal that the person is not an abuser. The numerous cold medications that contain ephedrine and pseudoephedrine can also cause a false positive for amphetamine or methamphetamine on a urine drug screen.