invitation noun (ASK TO AN EVENT). A2 [C or U] the âact of âinviting someone to go to an âevent: Thanks for the invitation to âyour âbirthday âparty. I'm âhappy to âaccept âyour invitation. The first âday of the âexhibition will be by invitation (only) (= only those who have been âinvited can come).
fibrodysplasia ossificans progressiva. Description. Fibrodysplasia ossificans progressiva (FOP) is a disorder in which muscle tissue and connective tissue such as tendons and ligaments are gradually replaced by bone (ossified), forming bone outside the skeleton (extra-skeletal or heterotopic bone) that constrains movement.
FOP may eventually result in complete immobilization. Affected individuals may experience progressive pain and stiffness in affected areas, complete fusion of the spine, and/or pain in certain areas of the body caused by abnormal bony growths that compress the nerves in these areas (entrapment neuropathies).