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Vial: Once the vial is punctured, it is OPEN. Once you stick a needle in the vial, it is OPEN. OPEN vials can be stored in the fridge or at CONTROLLED room temperature. Regardless of where it is stored, OPEN insulin will only last 28 days before it must be thrown in the trash.
Quote from lpnandloveit1 I have always been told that the manufacturers exp date was for sealed unopened vials. Jun 9, '05. All multi-dose vials are marked when opened, usually insulin and such have a 30 day expiration date from date opened, but they never lasted that long on any unit I worked. If there is a change in color, nature, or if nurse feels vial was unsafe they were tossed.