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DRUG DESCRIPTION. WELLBUTRIN XLÂ® (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin reuptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines.
Last Updated Thursday, July 25, 2013 1:56PM EDT. Doctors are warning that an antidepressant sold under such names as Wellbutrin, as well as a smoking cessation drug called Zyban, is increasingly being abused by drug users â with often fatal results. The drug is a medication called bupropion that has long been hailed as a wonder drug. Itâs an antidepressant that has been used at different strengths for years to helped thousands of Canadians battle mood disorders, depression, seasonal affective disorder and to quit smoking.