Raf-1 proto-oncogene, serine/threonine kinase. Normal Function. The RAF1 gene provides instructions for making a protein that is part of a signaling pathway called the RAS/MAPK pathway, which transmits chemical signals from outside the cell to the cell's nucleus.
The first was The Goonies in 1984, followed closely by Short Circuit in 1985. Actually only a fraction of Short Circuit was actually filmed in Astoria, but this cozy town, with it's unique winding streets and Victorian houses and the unmistakable Astoria Bridge, leaves a lasting impression. There's something pretty special about it even when it is not seen through the lens of a movie camera.
Main Street Station. Downtown. The movie opens with Robert De Niro getting into a car that explodes once the keyâs in the ignition. The scene was filmed in the parking lot of Main Street Station with the California Hotel & Casino in the background, and they had to blow-up at least three cars before they got the shot just right.