The Mediterranean Sea is a large sea that is located between Europe, northern Africa and southwestern Asia. Its total area is 970,000 square miles (2,500,000 sq km) and its greatest depth is located off the coast of Greece at around 16,800 feet (5,121 m) deep.
3. Inflammation of the nodes: buboes; Lymph nodes can become cancerous tissues and metastesize. Other Lymphoid Organs. Spleen: Filters and purifies lymph nodes. (macrophages and lymphocytes in spleen fights bacteria, toxins and viruses, removes cellular debris). Distributes and recycles aged RBC);.
Macrophages are a primary source of pro-inflammatory cytokines secreted by adipose tissue. The primary adipokine responsible for this infiltration is monocyte chemotactic protein-1 (MCP-1). As the level of macrophages increases in adipose tissue the level of pro-inflammatory cytokine secretion by the tissue increases.dipose tissue is not merely an organ designed to passively store excess carbon in the form of fatty acids esterified to glycerol (triglycerides).