Many urban legends are framed as complete stories with plot and characters. The compelling appeal of a typical urban legend is its elements of mystery, horror, fear or humor.Often they serve as cautionary tales.ecause people frequently allege that such tales happened to a  friend of a friend  (FOAF), the phrase has become a commonly used term when recounting this type of story. Sometimes urban legends are repeated in news stories, or distributed by e-mail or social media.
We have mast cells in the stomach wall. Somastatain-which is produced from d cells in the stomach wall is a known mast cell activator. We also know stress-in particular substance p and CRH also cause mast cells to spill contents. Histamine which we know is a chemical constantly released.
1 Non-mast cell histamine is released in the brain where it acts as a neurotransmitter. 2  The histamine neurons are found in the tuberomammillary nuclei of the posterior hypothalamus. 3  From there, they extend throughout the brain into the cortex and medial forebrain bundle.ites of histamine release. 1  Much of the histamine in the body is produced by the granules in mast cells and basophils as part of a local immune response to the presence of invading bodies. 2  Another important site where histamine is stored and released is in the enterochromaffin-like (ECL) cells of the stomach.