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Medical Definition of degenerative. : of, relating to, involving, or tending to cause degeneration degenerative conditions of the nervous systemâMorris Fishbein degenerative changes a degenerative muscle disorder.
Define degenerative. degenerative synonyms, degenerative pronunciation, degenerative translation, English dictionary definition of degenerative. adj. Of, relating to, causing, or characterized by degeneration: a degenerative disease. adj getting steadily worse adj. 1. tending to degenerate. Degenerative - definition of degenerative by The Free Dictionary