The Philippines is in Southeast Asia but is not on a continent, strictly speaking. The Philippines is an archipelago (string of islands) separated by bodies of water from mainâ¦land Asia.
Hence, change in the operation is a suitable and optimized way to make the some drug more effective by slight alteration in the drug delivery. Sustained Release is also providing promising way to decrease the side effect of drug by preventing the fluctuation of the therapeutic concentration of the drug in the body. Keyword: Sustained Release Drug Delivery System, Controlled Drug Delivery 1.
Dechallenge = withdraw of drug â¢ resolution of suspected ADR when the drug is withdrawn is a strong, although not conclusive indication of drug-induced disease. â¢ In cases where a withdrawal reaction is experienced, a dechallenge is when the drug is again given to the patient. â¢ âPositiveâ dechallenge = improvement of reaction when dechallenge occurs Rechallenge = reintroducing the drug after a dechallenge. â¢ this is only justifiable when the benefit of re-introducing the drug to the patient outweighs the risk of recurrence of the reaction.