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The mean terminal plasma elimination half-lives of racemic tramadol and racemic M1 are 6.3Â±1.4 and 7.4Â±1.4 hours, respectively. The plasma elimination half-life of racemic tramadol increased from approximately six hours to seven hours upon multiple dosing.
Tramadol (Ultram) is a drug similar to Codeine and is also an Opioid (derived from the Opium Poppy or similar to drugs derived from it). It will cause sedation, possible eupho â¦ ria, respiratory depression, pain relief, itching, constipation, nausea and a host of other side effects.