The Mediterranean Sea is a large sea that is located between Europe, northern Africa and southwestern Asia. Its total area is 970,000 square miles (2,500,000 sq km) and its greatest depth is located off the coast of Greece at around 16,800 feet (5,121 m) deep.
3. Inflammation of the nodes: buboes; Lymph nodes can become cancerous tissues and metastesize. Other Lymphoid Organs. Spleen: Filters and purifies lymph nodes. (macrophages and lymphocytes in spleen fights bacteria, toxins and viruses, removes cellular debris). Distributes and recycles aged RBC);.
Macrophages Macrophages are the body's first line of defense and have many roles. A macrophage is the first cell to recognize and engulf foreign substances (antigens). Macrophages break down these substances and present the smaller proteins to the T lymphocytes.