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The recommended starting dose of Zoloft for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is Zoloft 25 mg once a day.
Here, the medication doses were high. In adults, the standard Zoloft dose for depression is 50 mg daily. A number of patients in my practice have done well on 25 mg. To treat anxiety, the starting doses tend to be low; at first, antidepressants can increase anxiety.