Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes and extra fluid from the blood to form urine. Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. 2  Autosomal dominant PKD is the most common inherited form while autosomal recessive PKD is a rare.
Alabama's Mountain Region contains the state's largest lake: Lake Guntersville. Cradled in the Appalachian foothills of northern Alabama, Lake Guntersville is located between Bridgeport and Guntersville, stretching out over 75 miles into Tennessee (near Chattanooga) and occupying 69,000 acres.
Alabama has many rivers and water bodies. All the rivers of the state flow into the Gulf of Mexico. The major rivers are: Lakes. The major lakes of Alabama are: 1  East Gulf Coastal Plain: More than two-thirds of Alabama is covered by the East Gulf Coastal Plain. 2  The area consists of lowlands and low ridges. 3  Between the southern and northern east Coastal Plain lies the Black Belt Prairie, which is home to many plantations.