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The recommended starting dose of Zoloft for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is Zoloft 25 mg once a day.
Maintenance doses for the treatment of obsessive-compulsive disorder with Zoloft range from 50 mg to 200 mg per day. Changes in dosage should not occur at intervals of less than one week because of the long elimination half-life of Zoloft of 24 hours.: Zoloft (sertraline) is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). It is commonly used to treat depression, social anxiety disorder, posttraumatic stress disorder (PTSD), panic disorder and obsessive-compulsive disorder (OCD).