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The mean terminal plasma elimination half-lives of racemic tramadol and racemic M1 are 6.3Â±1.4 and 7.4Â±1.4 hours, respectively. The plasma elimination half-life of racemic tramadol increased from approximately six hours to seven hours upon multiple dosing.
Lorcet is a combination, narcotic pain reliever containing both hydrocodone and acetaminophen. The half-life of hydrocodone can range from 3.5 to 4.1 hours. The acetaminophen plasma half-life ranges from 1.25 to 3 hours, but may be increased in the presence of liver damage or overdosage.: How long Lorcet (hydrocodone/acetaminophen) stays in urine may vary depending upon several patient specific factors, such as dosage and acute versus chronic administration. However, the main variable for how long Lorcet stays in urine is the half-life of the medication.