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Fluid-mosaic model. 1  Plasma membrane consists of a phospholipid bilayer studded with proteins, polysaccharides, lipids. 2  The lipid bilayer is semipermeable Regulates passage of substances into and out of the cell. H2O and some small, uncharged, molecules (O2, CO2) can pass through.
All cells have an outer plasma membrane that regulates not only what enters the cell, but also how much of any given substance comes in. Unlike prokaryotes, eukaryotic cells also possess internal membranes that encase their organelles and control the exchange of essential cell components. Both types of membranes have a specialized structure that facilitates their gatekeeping function.