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Medical Definition of degenerative. : of, relating to, involving, or tending to cause degeneration degenerative conditions of the nervous systemâMorris Fishbein degenerative changes a degenerative muscle disorder.
Degeneration. go to hell in a handbasket To indulge in petty or sporadic dissipation; to carouse occasionally, in a small way; to degenerate bit by bit; gradually to go downhill morally. This slang expression is often used to describe typically adolescent anti-social behavior, usually of a temporary nature.. The state of being degenerate. 3. Medicine Gradual deterioration of specific tissues, cells, or organs with corresponding impairment or loss of function, caused by injury, disease, or aging. 4. Biology The evolutionary decline or loss of a function, characteristic, or structure in an organism or species.