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Fluid-mosaic model. 1  Plasma membrane consists of a phospholipid bilayer studded with proteins, polysaccharides, lipids. 2  The lipid bilayer is semipermeable Regulates passage of substances into and out of the cell. H2O and some small, uncharged, molecules (O2, CO2) can pass through.
Neurons carry out their specialized functions of communication and integration because their outer cell membrane has special properties. The cell membrane separates the inside of a cell (all cells, not just neurons) from the outside, and all chemicals that get into and out of the cell must go thorough it. As in all cells, the cell membrane of a neuron is polarized. This means that there is an electrical difference across the cell membrane. The polarization of a cell can be measured by putting a very thin electrode inside a cell, as illustrated in Figure 3.