Just a couple of thoughts. As cells get bigger, the components (used to be called organelles but I guess that's changed) get further from the cell walls or membranes.
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Middlesex County, Massachusetts. Middlesex County is a county in the Commonwealth of Massachusetts, in the United States. As of 2014, the estimated population was 1,570,315, making it the twenty-third most populous county in the United States, and the most populous county in both Massachusetts and New England.