Therefore, whenever a ddNTP is added to a growing DNA strand, it is unable to chemically bind with the next nucleotide in the chain, and the DNA strand stops growing. Figure 3: By adding together information about all of the truncated strands, researchers can determine the nucleotide sequence of the DNA target.
Functions of the Bladder. Temporary store of urine â The bladder is a hollow organ. The walls are very distensible, with a folded internal lining (known as rugae), this allows it to hold up to 600ml. Assists in the expulsion of urine â During voiding, the musculature of the bladder contracts, and the sphincters relax.
The urinary bladder is made of several distinct tissue layers: 1  The innermost layer of the bladder is the mucosa layer that lines the hollow lumen. 2  Surrounding the mucosal layer is the submucosa, a layer of connective tissue with blood vessels and nervous tissue that supports and controls the surrounding tissue layers. The visceral muscles of the muscularis layer surround the submucosa and provide the urinary bladder with its ability to expand and contract.