Raf-1 proto-oncogene, serine/threonine kinase. Normal Function. The RAF1 gene provides instructions for making a protein that is part of a signaling pathway called the RAS/MAPK pathway, which transmits chemical signals from outside the cell to the cell's nucleus.
The first was The Goonies in 1984, followed closely by Short Circuit in 1985. Actually only a fraction of Short Circuit was actually filmed in Astoria, but this cozy town, with it's unique winding streets and Victorian houses and the unmistakable Astoria Bridge, leaves a lasting impression. There's something pretty special about it even when it is not seen through the lens of a movie camera.
Bill Owen (who played Compo) made the area his second home. He died in July 1999 and is buried nearby in the village of Upperthong. Many of the canal scenes in Last of the Summer Wine were filmed at Slaithwaite, which is frequently used as a location in ITV's 'Where the Heart Is'.Slaithwaite features in the canal section of this web site.Bamforths produced their saucy seaside postcards of nagging (buxom) wives and their (scrawny) hen pecked husbands at Holmfirth. Bamforths were also producers of 'Magic Lantern' slide shows and silent films.t's 'easy watching' TV, in the same mould as Heartbeat, Monarch Of The Glen, Where the Heart is and Ballykissangel. Downham's village pub, the Assheton Arms features in the programme as The Signalman's Arms. Damens railway station (Britain's smallest) is 20 miles from Downham and is seen as Ormston in the TV series.