The neuromuscular junction is the site of the signal exchange. The steps of this process in vertebrates occur as follows:(`) The action potential reaches the axon terminal. (2) Voltage-dependent calcium gates open, allowing calcium to enter the axon terminal.he neuromuscular junction is the site of the signal exchange. The steps of this process in vertebrates occur as follows:(`) The action potential reaches the axon terminal. (2) Voltage-dependent calcium gates open, allowing calcium to enter the axon terminal.
Find out more about the common causes, symptoms, diagnosis and treatment options for pain on outside of foot in the ankle sprain section. 3) Cuboid Syndrome Cuboid Syndrome is a less common cause of lateral foot pain (i.e. outer side of foot pain) but it frequently goes undiagnosed which can lead to symptoms being present for long periods. It is caused by one of the small foot bones, the cuboid, being partially dislocated out of position following an injury like an ankle sprain or from repetitive strain on the foot.
Sciatica is a condition caused by irritation of the sciatic nerve and you'll feel the effects as numbness in one leg or foot, a shooting pain down the back of one thigh or in your buttock, and pain in the leg when you sit, stand, strain, cough and sneeze.. Guillain-Barre Syndrome Can Cause Numb Legs. Guillain-Barre syndrome is a condition where your immune system attacks your own nerves. The condition causes weakness and tingling in your hands and feet, which spreads to the rest of the body including the legs.