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Fluid-mosaic model. 1  Plasma membrane consists of a phospholipid bilayer studded with proteins, polysaccharides, lipids. 2  The lipid bilayer is semipermeable Regulates passage of substances into and out of the cell. H2O and some small, uncharged, molecules (O2, CO2) can pass through.
How does the cell membrane control what substances enter and leave the cell? The cell membrane is partially permeable and it is designed in a way such that only particular objects can enter and leave; the process by which they enter and exit the ce â¦ ll is known as diffusion which occurs due to osmosis.