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[edit on Wikidata] Pituitary ACTH hypersecretion (or Cushing disease) is a form of hyperpituitarism characterized by an abnormally high level of ACTH produced by the anterior pituitary. It is one of the causes of Cushing's syndrome. (However, Cushing's syndrome can be caused by many other causes, including exogenous administration.) ^ Drouin J, Bilodeau S, Vallette S (September 2007). Of old and new diseases: genetics of pituitary ACTH excess (Cushing) and deficiency.
Chronic excessive levels of cortisol are seen in a condition known as Cushing's syndrome. And chronically low, and insufficient levels of cortisol are seen in Addison's disease. The third group of steroids secreted by the adrenal cortex is the gonadocorticoids, or sex hormones.