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The recommended starting dose of Zoloft for people with panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is Zoloft 25 mg once a day.
Zoloft and its generic forms come in both tablet and oral concentrate form. Typical dosage for treating depression is 50 mg once a day. But, the dose varies for other indications. Zoloft has a 24-hour elimination half-life, so changes in dose should not occur in intervals less than one week.