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Lipase is a digestive enzyme produced by the following organs: pancreas (pancreatic lipase), liver (hepatic lipase), and stomach (stomach/gastric lipase). Enzymes are responsible for the metabolism of carbohydrates, proteins, and fats.
1 Gastric Lipase: Gastric lipase is an acidic lipase secreted by the gastric chief cells in the fundic mucosa in the stomach. 2  It has a pH optimum of 3-6. 3  Gastric lipase, together with lingual lipase, comprise the two acidic lipases.