That's a good question. I can imagine that there was a time before there was life on Earth, and then clearly there was a time X-hundred thousand years or a million years later when there were things that we would all recognize as biological.
A high count indicates the presence of inflammation in the body. Because white blood cells are calculated by the number of cells per volume of blood, test results can vary between labs. Different labs use different degrees of measurements for the white blood cell count.
When I examined this person's chart, she had Neptune in Libra conjunct her Ascendant with three hard aspects, so I told her: Bottom line is, you have dirty blood and this is what is the root cause of your high white blood count.. At that point, I told her what to do to clean out her kidneys.