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Full Text. Each protein has its own unique sequence of amino acids and the interactions between these amino acids create a specify shape. This shape determines the protein's function, from digesting protein in the stomach to carrying oxygen in the blood. Changing the Shape of a Protein.
For a large subset of proteins, phosphorylation is tightly associated with protein activity and is a key point of protein function regulation. Phosphorylation regulates protein function and cell signaling by causing conformational changes in the phosphorylated protein. These changes can affect the protein in two ways.