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Radioactive iodine is typically used in thyroid tests, including a thyroid scan. Your thyroid and most types of thyroid cancer absorb iodine naturally. The radioactive iodine builds up in your thyroid tissue. A gamma camera or scanner detects the radioactive emissions.
A nonfunctioning nodule does not take up iodine and produces a localized  cold  area on the image of the thyroid gland. In addition, thyroid scanning can be done to help determine if thyroid cancer has spread beyond the bed of the thyroid in the neck. For this purpose, usually a whole body thyroid scan is performed.n this case the scan reveals increased iodine uptake by the whole gland. In addition, a thyroid scan can provide information on specific areas within the thyroid gland and can help to determine whether any localized areas are hyperfunctioning or under functioning compared to the rest of the gland.