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Full Text. Each protein has its own unique sequence of amino acids and the interactions between these amino acids create a specify shape. This shape determines the protein's function, from digesting protein in the stomach to carrying oxygen in the blood. Changing the Shape of a Protein.
For a large subset of proteins, phosphorylation is tightly associated with protein activity and is a key point of protein function regulation. Phosphorylation regulates protein function and cell signaling by causing conformational changes in the phosphorylated protein. These changes can affect the protein in two ways. First, conformational changes regulate the catalytic activity of the protein.