Patients with insulin-resistant type 1 or type 2 diabetes who require daily insulin doses of more than 200 units may find U-500 insulin to be useful; larger doses may be administered subcutaneously in a reasonable volume.
Definition of beam 1 a: a long piece of heavy often squared timber suitable for use in construction b weaving: a wood or metal cylinder in a loom on which the warp (see 1 warp 1a) is wound
Meaning strong horizontal beam is from c.1600. Meaning dormant or inoperative thing is from 1620s. Meaning railroad sleeping car is from 1875. Sense of something whose importance proves to be greater than expected first attested 1892, originally in American English sports jargon, probably from earlier (1856) gambling slang sense of unexpected winning card.