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Fluid-mosaic model. 1  Plasma membrane consists of a phospholipid bilayer studded with proteins, polysaccharides, lipids. 2  The lipid bilayer is semipermeable Regulates passage of substances into and out of the cell. H2O and some small, uncharged, molecules (O2, CO2) can pass through.
The cell membrane is freely permeable to water. The membrane cannot prevent water from entering or leaving the cell. Water diffuses through the membrane by a process we call. osmosis. . Osmosis is the movement of water through a. membrane from high to low concentration. Whether water goes in or out of a cell depends upon the water. concentration inside and outside the cell. Some dissolved substances can diffuse through a cell membrane too.