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The goal of treatment for advanced Parkinsonâs disease should be on providing patients with safety, comfort, and quality of life. Levadopa (L-dopa) Levodopa, also called L-dopa, which is converted to dopamine in the brain, remains the gold standard for treating Parkinson's disease. The standard preparations (Sinemet, Atamet) combine levodopa with carbidopa, which improves the action of levodopa and reduces some of its side effects, particularly nausea.
The goal of medical management of Parkinson's disease is to control signs and symptoms as long as possible, while minimizing side effects. Medications usually provide good control for 4 to 6 years. After this time period, disability usually progresses despite medical management, and many people develop long-term motor complications including fluctuations and an inability to control their muscles called dyskinesia.