Raf-1 proto-oncogene, serine/threonine kinase. Normal Function. The RAF1 gene provides instructions for making a protein that is part of a signaling pathway called the RAS/MAPK pathway, which transmits chemical signals from outside the cell to the cell's nucleus.
The first was The Goonies in 1984, followed closely by Short Circuit in 1985. Actually only a fraction of Short Circuit was actually filmed in Astoria, but this cozy town, with it's unique winding streets and Victorian houses and the unmistakable Astoria Bridge, leaves a lasting impression. There's something pretty special about it even when it is not seen through the lens of a movie camera.
'The Wonder Years'-style show being filmed in Des Moines. Scenes from a new '90s-era sitcom will be easily recognizable to Des Moines residents. The comedy series Play by Play is being filmed in and around the capital city â most notably at Roosevelt High School and North High School's Grubb Stadium. The show's producer, Kevin Mann, describes it as a coming-of-age story in the same vein as The Wonder Years..