Collagen is a natural protein component of the skin that acts like a scaffold and the main building block for cells, tissues and organs. About a third of the protein content in your body is made up of collagen, which is found in the bones, muscles, and tissues of the organs.
1 There can be the accumulation of fluid on the knee after an accident. 2  In most cases, the fluid is blood which can be through a fracture caused to the knee. 3  The swelling of the knee often takes place within some minutes of the injury occurring. 4  Gout and pseudo-gout can also cause fluid on the knee.
Knee effusion. A small amount of fluid exists in normal joints. Knee effusion is a condition in which excess fluid accumulates around your knee joint as a result of overusing your knee, injuring your knee or having an underlying disease.