Amputation may also be done for serious infections that do not respond to antibiotics or other treatment. In some cases, it may be done due to frostbite or neuroma. This is a thickening of nerve tissue. There may be other reasons you may need an amputation. What are the risks for amputation?
Muscular System. The muscular system is made up of tissues that work with the skeletal system to control movement of the body. Some musclesâlike the ones in your arms and legsâare voluntary, meaning that you decide when to move them. Other muscles, like the ones in your stomach, heart, intestines and other organs, are involuntary.
1 The bones of the skeletal system protect the body's internal organs, support the weight of the body, and serve as the main storage system for calcium and phosphorus.  The muscles of the muscular system keep bones in place; they assist with movement by contracting and pulling on the bones.