Alleles for a particular phenotype determine what characteristic an organism will express, as with the following example where. 1  Chromosome 1 contains an allele for blonde hair. 2  Chromosome 2 contains an allele for brown hair. 3  Chromosome 3 contains an allele for blue eyes. 4  Chromosome 4 contains an allele for brown eyes.
Because of the patient's smoking history and abnormal chest radiograph, a neoplasm was initially suspected as a cause of SIADH. The head trauma was too remote to be of concern. Although 1 case of risperidone-associated hyponatremia has been reported, the risk seems low with this agent and with olanzapine.
Drugs Causing Lowering of Sodium Level or Hyponatremia. Drugs are one of the causes implicated in the development of lowering of sodium level or hyponatremia. Diuretics: Thiazides, bumetanide, indapamide, ethacrynic acid, furosemide. Diuretics affect the balance between sodium and water and are among the most common drugs implicated in the development of hyponatremia. Antidepressants: Selective serotonin reuptake inhibitors, tricyclic antidepressants (amitriptyline, protriptyline, desipramine), monoamine oxidase inhibitors, venlafaxine.