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BUT Wellbutrin is also known to increase anxiety in certain patients. It's not an SSRI medication like most anti-depressants prescribed today (SSRIs are serotonin related) such as Paxil, Prozac, Zoloft and other popular SSRIs. Wellbutrin deals with dopamine receptors in our brain.
Wellbutrin is a norepinephrine and dopamine reuptake inhibitor, or NDRI for short. NDRIs affect specific chemicals within the brain, known as norepinephrine and dopamine. These are two of several chemicals used to send messages from one nerve cell to another.