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Salmeterol is a long-acting beta2-adrenoceptor agonist (LABA), used in moderate to severe persistent asthma following previous treatment with a short-acting beta2-adrenoceptor agonist (SABA) such as salbutamol (albuterol).he primary noticeable difference of salmeterol from salbutamol, and other short-acting beta2-adrenoceptor agonists (SABAs), is its duration of action. Salmeterol lasts approximately 12 hours in comparison with the salbutamol, which last about 4â6 hours.
Seretide Accuhaler. Clinical trials have investigated the safety and efficacy data of fluticasone. propionate/salmeterol (Seretide) at three dose strengths (100/50ï­g, 250/50ï­g and 500/50ï­g) in the treatment of patients with reversible obstructive airways disease and asthma. Six.