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Scarred glomeruli in the kidney of a person with diabetic nephropathy. [edit on Wikidata] Diabetic nephropathy (or diabetic kidney disease) is a progressive kidney disease caused by damage to the capillaries in the kidneys' glomeruli. It is characterized by nephrotic syndrome and diffuse scarring of the glomeruli.
The cause of diabetic nephropathy is not well understood, but it is thought that high blood sugar, advanced glycation end product formation, and cytokines may be involved in the development of diabetic nephropathy. Kidney damage is likely if one or more of the following is present: Poor control of blood glucose.