Other signs and symptoms of HIV infection include: 1  genital ulcers. 2  genital warts. 3  severe mucosal herpes infections.
1 Pain, swelling, redness, and warmth that develop suddenly in a big toe joint may be caused by gout. 2  Other conditions or diseases that may cause inflammation include: 3  Arthritis or rheumatic diseases. 4  Retrocalcaneal bursitis and tendinitis, which can occur from overuse injuries.
It is the effect of damage to the nerves in the big toe. The numb toe is accompanied by burning sensation sometimes. The cause of numbness in the toes includes chronic medical disorders, lifestyle factors and environmental exposures. In the following article, there are causes and treatment of big toe numbness.