Other signs and symptoms of HIV infection include: 1  genital ulcers. 2  genital warts. 3  severe mucosal herpes infections.
1 Pain, swelling, redness, and warmth that develop suddenly in a big toe joint may be caused by gout. 2  Other conditions or diseases that may cause inflammation include: 3  Arthritis or rheumatic diseases. 4  Retrocalcaneal bursitis and tendinitis, which can occur from overuse injuries.
There are several diseases that can cause joint pain and swelling. Examples of these diseases include: Gout: This is a type of arthritis which causes acute pain stiffness and joint swelling. The disorder commonly affects the big toe and the joint swelling can be continuous unless the disorder is treated.