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1 People often experience an upset stomach, diarrhea (possibly bloody), abdominal pain and painful swallowing when using aspartame as a sweetener.  Skin and Allergies. Hives and intense itching, lip or mouth swelling and worsening of asthma all can occur due to aspartame.
Most chewing gum is sweetened with aspartame. Long term use of aspartame has been linked with cancer, diabetes, neurological disorders, and birth defects. If your gum isn't sweetened with aspartame, it is probably sweetened with sugar. Regular intake of refined sugar is most likely the single greatest dietary cause of chronic health challenges like cancer, atherosclerosis, and diabetes mellitus type 2.