Other signs and symptoms of HIV infection include: 1  genital ulcers. 2  genital warts. 3  severe mucosal herpes infections.
1 Pain, swelling, redness, and warmth that develop suddenly in a big toe joint may be caused by gout. 2  Other conditions or diseases that may cause inflammation include: 3  Arthritis or rheumatic diseases. 4  Retrocalcaneal bursitis and tendinitis, which can occur from overuse injuries.
Some reasons for swelling may be: 1  Sprained ankle or joint. 2  Sunburn. 3  Allergic reaction to insect bites or plants.  Thrombosis (blockage in 1  veins) Lymphatic obstruction.  Fractured or broken 1  bones. Dislocation of a 2  joint. Complications with pregnancy.  Tendon or 1  muscle tears. Infection.  Pre-cancerous tumor.