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Meatloaf is done when a meat thermometer inserted in its center reads 160 degrees Fahrenheit. Ground beef used for food items like hamburgers or meatloaf should be at this temperature after it is cooked.
Mix ground beef, bread crumbs, ... on bottom rack of oven. Final internal temperature should be 170F for ground beef. Ovens vary, so check meatloaf after 1 hour. Mix all ingredients in a bowl and then put into a baking dish and bake at 375F degrees for about 50 minutes or until done. Then add the topping mixture and ...