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Summary Summary. Abetalipoproteinemia is a condition characterized by the inability to fully absorb dietary fats, cholesterol and fat-soluble vitamins. Signs and symptoms appear in the first few months of life and can include failure to thrive; diarrhea; acanthocytosis; and stool abnormalities.
3. Pleiotropy (or pliotropy) is the phenomenon in which a single gene conditions several different phenotypical traits. Some phenotypical traits may be sensitive to the pleiotropic effects (for example, inhibition) of other genes, even when conditioned by a pair of alleles in simple dominance.A mixture of pleiotropy and gene interaction is characteristic of these cases.1  Non-Mendelian Inheritance-Image Diversity: pleiotropy.ome phenotypical traits may be sensitive to the pleiotropic effects (for example, inhibition) of other genes, even when conditioned by a pair of alleles in simple dominance. A mixture of pleiotropy and gene interaction is characteristic of these cases. 1  Non-Mendelian Inheritance-Image Diversity: pleiotropy.