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Salmeterol is a long-acting beta2-adrenoceptor agonist (LABA), used in moderate to severe persistent asthma following previous treatment with a short-acting beta2-adrenoceptor agonist (SABA) such as salbutamol (albuterol).he primary noticeable difference of salmeterol from salbutamol, and other short-acting beta2-adrenoceptor agonists (SABAs), is its duration of action. Salmeterol lasts approximately 12 hours in comparison with the salbutamol, which last about 4â6 hours.
Picloram is the most persistent of its family of herbicides. It does not adhere to soil and so may leach to groundwater, and has in fact been detected there. It is degraded in soil and water mainly by microbes. Picloram has very little tendency to accumulate in aquatic life.icloram is of moderate toxicity to the eyes and only mildly toxic on the skin. There is no documented history of human intoxication by picloram so symptoms of acute exposure are difficult to characterize.