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Edema. Edema or oedema, formerly known as dropsy or hydropsy, is an abnormal accumulation of fluid in the interstitium, which are locations beneath the skin or in one or more cavities of the body. It is clinically shown as swelling.dema or oedema, formerly known as dropsy or hydropsy, is an abnormal accumulation of fluid in the interstitium, which are locations beneath the skin or in one or more cavities of the body.
Edema is observable swelling from fluid accumulation in body tissues. Edema most commonly occurs in the feet and legs, where it is referred to as peripheral edema. The swelling is the result of the accumulation of excess fluid under the skin in the spaces within the tissues.All tissues of the body are made up of cells and connective tissues that hold the cells together. The edema that occurs in diseases of the heart, liver, and kidneys is mainly caused by salt retention, which holds the excess fluid in the body. 2  In certain liver and kidney diseases, low levels of albumin in the blood can contribute to fluid retention.