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Causes of sepsis. Sepsis can be triggered by an infection in any part of the body. The most common sites of infection leading to sepsis are the lungs, urinary tract, tummy (abdomen) and pelvis. Sepsis may develop when you're already in hospital. For example, you're more likely to develop sepsis if:
Any infection can lead to sepsis, but certain infections and their germs are more likely to cause it. Sepsis is most often associated with infections of the skin, gut, lungs (like pneumonia) and urinary tract (such as a kidney infection). Urosepsis complicates a urinary tract infection.