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Meatloaf is done when a meat thermometer inserted in its center reads 160 degrees Fahrenheit. Ground beef used for food items like hamburgers or meatloaf should be at this temperature after it is cooked.
Instructions. Preheat your oven to 325 degrees F. Place the frozen, foil-wrapped meatloaf in a shallow baking pan. Place the baking pan on the preheated oven's center rack. Bake the meatloaf for one hour.Remove the meatloaf from the oven using pot holders. Unwrap the foil, and brush the top of meatloaf with a glaze if desired. Place the meatloaf back into the oven and bake, uncovered, for another 30 to 40 minutes, or until it reaches the proper temperature.Place an instant-read food thermometer into the center of the meatloaf to check it's temperature, which should register 165 degrees F.lace the meatloaf back into the oven and bake, uncovered, for another 30 to 40 minutes, or until it reaches the proper temperature. Place an instant-read food thermometer into the center of the meatloaf to check it's temperature, which should register 165 degrees F.