Other signs and symptoms of HIV infection include: 1  genital ulcers. 2  genital warts. 3  severe mucosal herpes infections.
1 Pain, swelling, redness, and warmth that develop suddenly in a big toe joint may be caused by gout. 2  Other conditions or diseases that may cause inflammation include: 3  Arthritis or rheumatic diseases. 4  Retrocalcaneal bursitis and tendinitis, which can occur from overuse injuries.
A traumatic injury, such as an ankle sprain or a broken ankle, is the most common cause of ankle swelling. Patients almost always remember the particular injury, but occasionally even subtle injuries can also lead to ankle swelling. Also, stress fractures can occur around the ankle joint leading to swelling. Gout.