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1 People often experience an upset stomach, diarrhea (possibly bloody), abdominal pain and painful swallowing when using aspartame as a sweetener.  Skin and Allergies. Hives and intense itching, lip or mouth swelling and worsening of asthma all can occur due to aspartame.
Sweeteners like aspartame and sorbitol are common ingredients and excessive ingestion of either can cause side effects. Sorbitol has been known to cause abdominal discomfort. Over consumption of chewing gum containing sorbitol has led to extreme weight loss, because of its laxative properties.