All protested trades are sent to the League Office for review, and will be evaluated within 12 hours of their submission for review. Note that the 12 hour League Office review period does not necessarily begin at the time the trade is first protested, but will not delay a trade beyond the original process time.
The nucleolus is contained within the cell nucleus. The nucleolus (/nuËËkliËÉµlÉs/ ; plural nucleoli /nuËËkliËÉµlaÉª/) is the largest structure in the nucleus of eukaryotic cells, where it primarily serves as the site of ribosome synthesis and assembly.ucleoli also have other important functions like assembly of signal recognition particles and playing a role in the cell's response to stress. Nucleoli are made of proteins and RNA and form around specific chromosomal regions.
Figure 1: Chromosomes are composed of DNA tightly-wound around histones. Chromosomal DNA is packaged inside microscopic nuclei with the help of histones. These are positively-charged proteins that strongly adhere to negatively-charged DNA and form complexes called nucleosomes.Each nuclesome is composed of DNA wound 1.65 times around eight histone proteins. Nucleosomes fold up to form a 30-nanometer chromatin fiber, which forms loops averaging 300 nanometers in length.he haploid human genome contains approximately 3 billion base pairs of DNA packaged into 23 chromosomes. Of course, most cells in the body (except for female ova and male sperm) are diploid, with 23 pairs of chromosomes.