Other signs and symptoms of HIV infection include: 1  genital ulcers. 2  genital warts. 3  severe mucosal herpes infections.
1 Pain, swelling, redness, and warmth that develop suddenly in a big toe joint may be caused by gout. 2  Other conditions or diseases that may cause inflammation include: 3  Arthritis or rheumatic diseases. 4  Retrocalcaneal bursitis and tendinitis, which can occur from overuse injuries.
This affects all the toes of the foot, especially the big toe. It is caused by excessive wear and tear of the feet joints and is associated with stiffness and pain in the joints. Trauma to the great toe can also cause osteoarthritis of the toe. It is more common in older individuals.