Fatigue may be related to: 1  Use of alcohol or drugs. 2  Excess physical activity. 3  Jet lag.  Lack of physical 1  activity. Lack of sleep.  Medications, such as antihistamines, cough 1  medicines. Unhealthy eating habits.
Difference between a Regulation, Directive and Decision. Regulations have binding legal force throughout every Member State and enter into force on a set date in all the Member States.
On the other hand, regulations refer to the directives or statute enforced by law, in a particular country. The primary difference between rules and regulation is that while the former do not as such have a legal binding, the latter have a legal binding.