Chest pain and shortness of breath if blood clots form in the blood vessels in your lungs and heart. Pain, redness, warmth, and swelling in the lower leg if blood clots form in the deep veins of your leg. Headaches, speech changes, paralysis (an inability to move), dizziness, and trouble speaking and understanding if blood clots form in the blood vessels in your brain. These signs and symptoms may indicate a stroke.
From Wikipedia, the free encyclopedia. A gene knockout (abbreviation: KO) is a genetic technique in which one of an organism 's genes is made inoperative (knocked out of the organism). knockout mouse (left) that is a model of obesity, compared with a normal mouse. A conditional knockout allows gene deletion in a tissue or time specific manner. This is done by introducing short sequences called loxP sites around the gene.
A laboratory mouse in which a gene affecting hair growth has been knocked out (left), is shown next to a normal lab mouse. Knocking out the activity of a gene provides information about what that gene normally does. Humans share many genes with mice.n some instances, the gene may serve a different function in adults than in developing embryos. Knocking out a gene also may fail to produce an observable change in a mouse or may even produce different characteristics from those observed in humans in which the same gene is inactivated.