People with Treacher Collins syndrome often have eyes that slant downward, sparse eyelashes, and a notch in the lower eyelids called an eyelid coloboma. Some affected individuals have additional eye abnormalities that can lead to vision loss.
Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin. For many animals, pantothenic acid is an essential nutrient.Animals require pantothenic acid to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats.hen found in foods, most pantothenic acid is in the form of CoA or acyl carrier protein (ACP). For the intestinal cells to absorb this vitamin, it must be converted into free pantothenic acid. Within the lumen of the intestine, CoA and ACP are hydrolyzed into 4'-phosphopantetheine.
Pantothenic acid was discovered in 1933 by Dr. R. J. Williams and was found to be a true vitamin shortly thereafter.Its name is derived from the Greek word pantos that means everywhere, which is appropriate for this widely distributed vitamin.Pantothenic acid is an integral part of coenzyme A and plays the important role of decarboxylating pyruvate in the citric acid cycle.ts name is derived from the Greek word pantos that means everywhere, which is appropriate for this widely distributed vitamin. Pantothenic acid is an integral part of coenzyme A and plays the important role of decarboxylating pyruvate in the citric acid cycle.