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Causes of sepsis. Sepsis can be triggered by an infection in any part of the body. The most common sites of infection leading to sepsis are the lungs, urinary tract, tummy (abdomen) and pelvis. Sepsis may develop when you're already in hospital. For example, you're more likely to develop sepsis if:
Early onset sepsis appears before the age of 3 days and late onset sepsis is when symptoms appear after 3 days of life. The cause of sepsis in newborns can be viral, bacterial, or fungal. Viral causes include enterovirus, herpex virus simplex, or adenovirus. The most common bacterial causes are Escherichia coli (E. coli) and group B streptococcus (GBS), which can be passed on to the infant during delivery.