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nephrosclerosis nephÂ·roÂ·scleÂ·roÂ·sis (nÄf'rÅ-sklÉ-rÅ'sÄ­s) n. Induration of the kidney from overgrowth and contraction of the interstitial connective tissue.
Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque. Initially, there are generally no symptoms. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems depending on the arteries which are affected.