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Eczema is an irritating, itchy rash on the skin. Hives can be very itchy. Wearing tight, scratchy clothing may cause an itchy rash. Contact with poison oak may result in an itchy rash.Allergies may manifest as skin rashes. It is important to keep a rash that has developed as a result of antibiotics as clean and as dry as possible. A topical cream can be applied to alleviate itchy skin.czema is an irritating, itchy rash on the skin. Hives can be very itchy. Wearing tight, scratchy clothing may cause an itchy rash. Contact with poison oak may result in an itchy rash.
1 Irritation and allergic reactions. 2  Wool, chemicals, soaps and other substances can irritate the skin and cause itching. 3  Sometimes the substance, such as poison ivy or cosmetics, causes an allergic reaction.auses. Possible causes of itchy skin include: 1  Dry skin. 2  If you don't see a crop of bright, red bumps or some other dramatic change in the itchy area, dry skin (xerosis) is a likely cause.