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The aging process is associated with changes in the composition and function of the immune system and these changes may occur at an accelerated rate in men as compared to women. Moreover, after the age of menopause, the incidence of chronic inflammatory disease in women approaches or exceeds that observed in males.he mechanisms responsible for sex-specific differences in the immune response are complex and likely involve effects of the sex hormones on the immune system, genetic factors, and gender-specific behaviors and exposures.
Autoimmune diseases affect the immune system, the bodyâs natural defenses for fighting disease. The immune system normally protects the body against foreign materials, such as viruses and bacteria. Autoimmune diseases result from a failure of the bodyâs own defenses against disease. The immune system loses its ability to tell the difference between foreign materials and its own cells. So the body starts attacking its own organs and tissues. There are three kinds of lupus. Discoid lupus affects only the skin and can be identified by red marks on the face or neck.