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DNA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule. Thus, it is a POLAR molecule which allows it to interact in an aqueous environment.NA is a polar molecule because it has a negatively (-) charged phosphate group attached to the 5' end of the molecule and a negatively charge hydroxl group (OH) attached to t â¦ he 3' prime end of the molecule.
Salt, which is used along with ethanol to force DNA to precipitate, interacts with DNA molecules to make it much less hydrophilic. Ethanol makes it easier for this interaction to take place. DNA is hydrophilic because of the negatively charged phosphate groups found along its sugar phosphate backbone.