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The aim of Bertoli was to determine the long-term effects of a ketogenic diet on body composition and bone mineral status of patients with GLUT-1 DS. Changes in body composition and bone mineral status were observed in adult patients with GLUT-1 DS who have been treated with a ketogenic diet for more than 5 years.
Could some of the adverse metabolic effects reported in this study support the long-expressed concerns about the high-fat Atkins diet? Specifically, should the conclusion of Johnston et al have been that a ketogenic diet that is high in saturated fat and cholesterol is not warranted for weight loss? It can be shown that a blanket rejection of ketogenic diets for weight loss is not warranted.