in the x direction, the water wants to flow in that direction) For a given hydraulic. conductivity, the vertical flow rate depends on the sum of the gravitational potential energy. gradient per unit weight of water (dz/dz =1) and the vertical gradient in soil water pressure.
Origin and spread of the 1278insTATC mutation causing TayâSachs disease in Ashkenazi Jews: Genetic drift as a robust and parsimonious hypothesis. Human Genetics 114 (4): 366â376. pmid 14727180.
Tay-Sachs disease is caused by a genetic mutation in the HEXA gene. This mutation affects the production of an enzyme called Hexosaminidase-A (Hex-A). Enzymes are proteins the body uses for chemical reactions.