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Human papilloma virus (HPV) is the major cause of cervical cancer. There are many different types of HPV. Some types of HPV cause genital warts and are sometimes called the genital wart virus.
The HPV type 1 causes most plantar warts. The virus gains access to the skin through direct contact. It is presumed that inoculation of the skin occurs in places likely to be contaminated by others with plantar warts, like communal showers. Once infected by HPV, spontaneous resolution seems to depend on the development of immune lymphocytes that destroy the virus-infected cells. Vaccines are available to protect against certain types of genital viral infections, but there are no vaccines for the HPV types that cause plantar warts.