MALIGNANCY. Low back pain at night that is not relieved by lying down may be caused by a tumor in the cauda equina (the roots of the spinal nerves controlling sensation in and movement of the legs), or a cancer that has spread to the spine from the prostate, breasts, or lungs. The pain is caused by irritation of a nerve root. 2  Sciatica is an example of radicular pain. 3  Referred. 4  The pain is perceived in the lower back but is caused by inflammation elsewhereâoften in the kidneys or lower abdomen.
While most moles donât turn into melanoma, researchers are unsure why some do. Like basal and squamous cell skin cancer, melanoma can be caused by UV rays. However, some melanomas can appear in body parts not exposed to sunlight. Both types of skin cancer occur when your skin cellsâ DNA has errors (or mutations). According to the Mayo Clinic, these errors cause skin cells to grow uncontrollably and form a mass of cancer cells.
Non melanoma skin cancer includes 2 main types: basal cell skin cancer and squamous cell skin cancer. They are named after the types of skin cells from which the cancers develop. It is possible for a non melanoma skin cancer to be a mixture of both these types. Non melanoma skin cancer is different from melanoma.