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The calculation of minute ventilation is simple: MV=TV*Rf or minute volume is equal to tidal volume (amount of air for one breath, ml) multiplied by the respiratory frequency (number of breaths per minute). This table shows normal minute ventilation (liters of air per minute) in healthy subjects at rest (14 studies).
1 Measure minute ventilation, arterial partial pressure of carbon dioxide (pCO 2) and oxygen (pO 2), and arterial pH after breathing normal air and then gas mixtures with either high carbon dioxide or low oxygen concentrations. 2  Discuss the role of arterial pCO 2, pO 2, and pH in regulation of pulmonary ventilation.