MALIGNANCY. Low back pain at night that is not relieved by lying down may be caused by a tumor in the cauda equina (the roots of the spinal nerves controlling sensation in and movement of the legs), or a cancer that has spread to the spine from the prostate, breasts, or lungs. The pain is caused by irritation of a nerve root. 2  Sciatica is an example of radicular pain. 3  Referred. 4  The pain is perceived in the lower back but is caused by inflammation elsewhereâoften in the kidneys or lower abdomen.
Skin Cancer Symptoms and Signs. BCC is the most common type of skin cancer and has a predilection for sun-exposed skin. Tumors may appear as a pearly or waxy bumps usually with visible blood vessels (nodular BCC), or as a flat scaly reddish patch (superficial BCC) with a brown border, or as a hard or scar-like lesion (sclerosing BCC).
Skin cancers are cancers that arise from the skin. They are due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. There are three main types of skin cancers: basal-cell skin cancer, squamous-cell skin cancer and melanoma. The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer. Basal-cell cancer grows slowly and can damage the tissue around it but is unlikely to spread to distant areas or result