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Small-scale mutations. 1  Point mutation â a change in one base in the DNA sequence. 2  Substitution â when one or more bases in the sequence is replaced by the same number of bases (for example, a cytosine substituted for an adenine).3  Inversion â when a segment of a chromosome is reversed end to end.arge-scale mutations. 1  Copy number variation (CNV) is a type of mutation where large chunks of DNA are inserted, repeated or lost. 2  These regions of DNA can be between 10,000 and 5,000,000 bases long. 3  Duplication of genes. 4  When there is an increase in the number of copies of a gene.
In this kind of mutations, DNA molecule divides even before the cell division starts. Types of Mutations:- Point Mutations:- Point mutations occur when a single nucleotide is replaced with another nucleotide base.Insertion and deletion come in this category. Error in the process of replication of DNA molecule results in point mutations.rameshift Mutations:- Mispairing of the DNA molecule causes the frameshift mutations. The changes in the single base pair nucleotide sequence usually insertion or deletion result in these mutations. The whole information coded in the amino acid changes due to frameshift mutations.