MALIGNANCY. Low back pain at night that is not relieved by lying down may be caused by a tumor in the cauda equina (the roots of the spinal nerves controlling sensation in and movement of the legs), or a cancer that has spread to the spine from the prostate, breasts, or lungs. The pain is caused by irritation of a nerve root. 2  Sciatica is an example of radicular pain. 3  Referred. 4  The pain is perceived in the lower back but is caused by inflammation elsewhereâoften in the kidneys or lower abdomen.
Skin Cancer Symptoms and Signs. BCC is the most common type of skin cancer and has a predilection for sun-exposed skin. Tumors may appear as a pearly or waxy bumps usually with visible blood vessels (nodular BCC), or as a flat scaly reddish patch (superficial BCC) with a brown border, or as a hard or scar-like lesion (sclerosing BCC).
Rarer types of non melanoma skin cancer. There are other less common types of skin cancer. These make up only about 1 out of every 100 (1%) skin cancers diagnosed in the UK. They are: Merkel cell carcinoma; Kaposiâs sarcoma; T cell lymphoma of the skin; These are all treated differently from basal cell and squamous cell skin cancers.