(rÄâ²dÃ¤r) 1. A method of detecting distant objects and determining their position, speed, or other characteristics by causing radio waves to be reflected from them and analyzing the reflected waves. The waves can be converted into images, as for use on weather maps.
A high level of the marker may indicate a worsened prognosis in some situations. The most effective and common purpose of tumor markers is to monitor the cancer treatment. As the cancer levels go on decreasing in the body, the marker also goes down. If the marker remains stagnant or increases, it is usually an indication that the patient is not responding sufficiently to the treatment.
In addition, cell cycle progression can be halted at several points by the tumor suppressor gene product p53, activated in response to checkpoints sensing DNA and possibly also chromosome damage; loss of p53 would remove this brake to cycling (8).