The names of some man-made satellites are Sputnik 1, Explorer 1, the International Space Station, ORBCOMM FM-107, Gonets-19 and SES-8. In 1957, Russia launched the first man-made satellite called Sputnik 1, and the United States sent Explorer 1 into orbit in 1958.
Many medications have been implicated in pedal edema, especially vasodilators, estrogens, NSAIDs, and calcium channel blockers. Dihydropyridine drugs are more likely than other calcium channel blockers to cause pedal edema.
NSAIDs, including ketoprofen immediate-release capsules and ketoprofen extended-release capsules, can cause serious gastrointestinal (GI) adverse events including inflammation, bleeding, ulceration, and perforation of the stomach, small intestine, or large intestine, which can be fatal.