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You can use most sugar substitutes if you have diabetes, including: 1  Saccharin (Sweet'N Low) 2  Aspartame (NutraSweet, Equal) 3  Acesulfame potassium (Sunett)  Sucralose (Splenda)
When the blood glucose level goes up. 1  Blood sugar (glucose) rises; 2  The pancreas detects the rise; 3  The pancreas pumps out insulin into the blood; 4  Insulin helps the uptake of glucose into muscles and other cells; 5  This causes the blood glucose level to fall to its normal set point; and. 6  The pancreas detects the fall and switches off insulin production. When the blood glucose level goes down. Blood sugar (glucose) drops; The pancreas detects the drop in blood sugar; The pancreas switches on the output of glucagon into the blood; Glucagon signals the liver to break down glycogen into glucose;