In adults, eczema occurs most frequently on the hands and elbows, and in bending areas such as the inside of the elbows and back of the knees. In young children, eczema is often seen on the elbows, knees, face, neck, and scalp. Signs and symptoms of atopic eczema include: 1  Itchiness. 2  Skin redness.
Sphingolipids are composed of a backbone of sphingosine which is derived itself from glycerol. Sphingosine is N-acetylated by a variety of fatty acids generating a family of molecules referred to as ceramides. Sphingolipids predominate in the myelin sheath of nerve fibers.
The core of a sphingolipid is an amino alcohol called sphingosine. Complex sphingolipids located in the plasma membrane of animal cells (especially nerve cells) have a structural function and are believed to protect the cell surface from harmful environmental factors.