Use a comma to separate nonessential elements from a sentence. More specifically, when a sentence includes information that is not crucial to the message or intent of the sentence, enclose it in or separate it by commas.
Genital warts are a sexually transmitted infection (STI) caused by certain strains of the human papillomavirus (HPV). These skin growths can cause pain, discomfort, and itching. They are especially dangerous for women because some types of HPV can also cause cancer of the cervix and vulva.
Viruses called human papillomavirus (HPV) cause warts. It is easier to catch a virus that causes warts when you have a cut or scrape on your skin. This explains why so many children get warts.