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Antibiotics can take two to three weeks to leave your system. They seem to work overtime to clean up your system even after you stop taking the pills. Also, some antibiotics work longer or shorter depending on the kind. For instance, Neomycin, is not completely absorbed into the blood system and is excreted out through urine and fecal matter. In this case, it is only in the system for 4-5 days.
ten to 14 days depending on the antibiotic prescribed although your symptoms may improve or disappear before you have taken all of your antibiotics you should complete your full course of treatment by taking all of the pills that were prescribed