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Pathophysiology of COPD. COPD is a complex syndrome comprised of airway inflammation, mucociliary dysfunction and consequent airway structural changes.1. Airway inflammation. COPD is characterized by chronic inflammation of the airways, lung tissue and pulmonary blood vessels as a result of exposure to inhaled irritants such as tobacco smoke.
Share on Google +. COPD, or chronic obstructive pulmonary disease, is a common lung disease that restricts airflow to the lungs, making it difficult to breathe. There are two forms of COPD: chronic bronchitis and emphysema.Regardless of the form, symptoms of the disease typically worsen over time.There are, however, a number of medications that assist with the symptoms of COPD, which include coughing, wheezing, shortness of breath, and life-threatening flare-ups.here are two forms of COPD: chronic bronchitis and emphysema. Regardless of the form, symptoms of the disease typically worsen over time. There are, however, a number of medications that assist with the symptoms of COPD, which include coughing, wheezing, shortness of breath, and life-threatening flare-ups.