In order to get inside the cell, these molecules must pass through porins, which are protein channels that span the outer membrane. Antimicrobial resistance mechanisms in Pseudomonas aeruginosa Gram-negative bacteria possess proteins called porins in their outer membranes that, when altered, reduce or halt drug absorption.
The Code of Federal Regulations (CFR) is a codification (arrangement of) the general and permanent rules published in the Federal Register by the executive departments and agencies of the Federal Government. e-CFR Updated Daily; Beta Site.
e-CFR. 1  This is a non-mandatory appendix to the asbestos standards for construction and for shipyards. 2  In addition, none of the criteria, both mandatory and recommended, are meant to specify or imply the need for use of patented or licensed methods or equipment.