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Tooth Abscess Antibiotics. Penicillin V. This is an earlier form of penicillin, and it is still very effective. It works against a relatively small number of bacteria types, the ones most commonly involved in dental infections. Because of this, it is less likely to cause antibiotic resistance.
Beta-lactam antibiotics. The Beta-lactam antibiotics are a broad class of antibiotics that includes the penicillins and the cephalosporins. Ceftriaxone (Rocephin), a cephalosporin, is sometimes given intravenously to patients with Lyme disease.enicillin antibiotics are historically significant because they were the first drugs that were effective against many previously serious diseases such as tuberculosis, syphilis, and staphylococcus infections. Penicillins are still widely used today, though many types of bacteria are now resistant.