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In addition, evidence on their combined effect on all-cause mortality is conflicting (17, 18). To address the interaction of obesity and OSA, we used a large historical cohort of patients with suspected OSA and investigated whether obesity influences the effect of nocturnal hypoxemia on cardiovascular events.
Medical Causes of Obesity Obesity is usually the result of overeating, but in a small percentage of people excess weight gain is a symptom of another disease. Medical causes of obesity can include: Hypothyroidism. This is a condition where the thyroid gland, located in the neck, produces too little thyroid hormone. Thyroid hormone regulates our metabolism. So too little hormone slows the metabolism and often causes weight gain.