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You can use most sugar substitutes if you have diabetes, including: 1  Saccharin (Sweet'N Low) 2  Aspartame (NutraSweet, Equal) 3  Acesulfame potassium (Sunett)  Sucralose (Splenda)
Some studies have linked artificial sweeteners, such as the aspartame (NutraSweet) used in many diet sodas, with weight gain. Weight gain increases insulin resistance, which leads to an increase in blood sugar level. However, this finding has not been confirmed in other studies.