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You can use most sugar substitutes if you have diabetes, including: 1  Saccharin (Sweet'N Low) 2  Aspartame (NutraSweet, Equal) 3  Acesulfame potassium (Sunett)  Sucralose (Splenda)
Ordering a diet Coke (filled with aspartame a very serious chemical) does not reverse pre diabetic high glucose and either does using Splenda. These are weak and ineffective choices that will not stop the power of high blood sugar wrecking your cells.rdering a diet Coke (filled with aspartame a very serious chemical) does not reverse pre diabetic high glucose and either does using Splenda. These are weak and ineffective choices that will not stop the power of high blood sugar wrecking your cells.