ATP Synthase is the terminal step of oxidative phosphorylation (cellular respiration). Complexes I, II, III, and IV take electrons from NADH or FADH(2) and transfer them to O2 to form H2O. During this process protons (H+) are pumped out of the mitochondrial matrix into the outer mitochondrial space. The proton gradient that is formed as a result of this pumping action is what drives ATP synthase to favor the formation of ATP from ADP plus phosphate. The transfer of electrons to O2 is coupled to the formation of ATP such that if there is no ADP and phosphate, the rate of respiration dramatically decreases.
GENERAL. 1  The Giant Maso Mastiff is a new and still a developing breed that is being developed with the aim to produce a healthier version of Old English Mastiff dog that can live longer. Originating in Germany, these dogs have more English Mastiff in them than the other parent breed, the Cane Corso Itliano.
The Old English Mastiff is a massive dog. The Mastiff has a large, heavy, square head with a well-marked stop between the eyes. The muzzle should be half the length of the skull.hat is the only way your relationship with your dog can be a complete success. Height, Weight Height: Males from 30 inches (76 cm) Females from 27 inches (69 cm) Weight: Males about 160 pounds (72 kg) Females about 150 pounds (68 kg) One of the heaviest breeds, a male Mastiff can exceed 200 pounds.