It is a common complication of diabetes. The most common cause is poorly controlled blood sugar over time. Diabetic nerve pain can take years to develop. In the early stages, you may have no signs at all, and then only start to feel a tingling or numbness in your feet. As it progresses, you may also feel the pain in your hands and it is often worse at night.
Lastly, the aging process affects how drugs are excreted (eliminated) from the body. The elderly have a decrease in kidney function and blood flow to the kidneys. Due to this decrease, it is common to decrease the dose of drugs that are eliminated by the kidneys.
Effect of cancer drugs on your liver. Some cancer drugs can affect the way that your liver works. This is most likely to happen with some chemotherapy drugs and some biological therapy drugs. The effect is usually mild and usually goes back to normal when the treatment ends.f you are having drugs that may affect the liver you will have a blood test before each treatment to check how well your liver is working. If the blood tests show that the treatment is affecting your liver, your doctors may change the dose of your treatment or give you a different treatment. Back to top.