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E. Coli. Eating undercooked ground beef is one of the main causes of E. coli, which can cause symptoms including diarrhea, vomiting and stomach cramps. These symptoms usually occur between two and eight days after eating contaminated food and can last for up to a week.
Meatloaf is done when a meat thermometer inserted in its center reads 160 degrees Fahrenheit. Ground beef used for food items like hamburgers or meatloaf should be at this temperature after it is cooked. Eating undercooked ground beef can lead to E.coli poisoning, according to KidsHealth.