ATP Synthase is the terminal step of oxidative phosphorylation (cellular respiration). Complexes I, II, III, and IV take electrons from NADH or FADH(2) and transfer them to O2 to form H2O. During this process protons (H+) are pumped out of the mitochondrial matrix into the outer mitochondrial space. The proton gradient that is formed as a result of this pumping action is what drives ATP synthase to favor the formation of ATP from ADP plus phosphate. The transfer of electrons to O2 is coupled to the formation of ATP such that if there is no ADP and phosphate, the rate of respiration dramatically decreases.
GENERAL. 1  The Giant Maso Mastiff is a new and still a developing breed that is being developed with the aim to produce a healthier version of Old English Mastiff dog that can live longer. Originating in Germany, these dogs have more English Mastiff in them than the other parent breed, the Cane Corso Itliano.
As to the extent that Latinate words such as  Dogo  or  Dogge  may be translated as mastiff, molosser breeds such as the Dogo Argentino and Dogo Canario may also be considered mastiffs. However, these terms may refer not only to breeds called mastiffs in English, but also to Bulldogs and pit bulls.