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Pathophysiology of COPD. COPD is a complex syndrome comprised of airway inflammation, mucociliary dysfunction and consequent airway structural changes.1. Airway inflammation. COPD is characterized by chronic inflammation of the airways, lung tissue and pulmonary blood vessels as a result of exposure to inhaled irritants such as tobacco smoke.
It can make your muscles ache and drain your energy. It can also cause you to have a headache, bad cough, and a fever. Most healthy people recover from these symptoms in a week or two. But for people with COPD or other long-term medical conditions, the flu can be worse and can cause serious complications.