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Pathophysiology of COPD. COPD is a complex syndrome comprised of airway inflammation, mucociliary dysfunction and consequent airway structural changes.1. Airway inflammation. COPD is characterized by chronic inflammation of the airways, lung tissue and pulmonary blood vessels as a result of exposure to inhaled irritants such as tobacco smoke.
Understanding COPD: Comorbidities. Comorbidities are two or more diseases existing at the same time in the body. They are common for people with COPD because organ systems work differently when they do not receive enough oxygen. When a resulting condition occurs, it can be considered comorbidity. Comorbidities are also difficult to manage for people who have COPD. People who have COPD should pay particular attention to their health at all times, and especially when another condition occurs. Below is a list of common comorbidities.