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Antibiotics can take two to three weeks to leave your system. They seem to work overtime to clean up your system even after you stop taking the pills. Also, some antibiotics work longer or shorter depending on the kind. For instance, Neomycin, is not completely absorbed into the blood system and is excreted out through urine and fecal matter. In this case, it is only in the system for 4-5 days.
Antibiotics usually start working in 24 to 36 hours.... Antibiotics usually start working in 24 to 36 hours, however when the infection is in a tooth or jaw (bone) it takes longer merely because the blood supply isn`t as good in that kind of tissue. Warm compresses help to increase the blood flow to the area and carry the meds to the area.