Since Imodium is an opiate, many people mistakenly assume that it will act as an opiate replacement medication. Since it does not activate receptors in the same way as replacement medications like buprenorphine, it will not work in the same manner. Opiate detox should always be done under medical supervision. At-home detox attempts using Imodium or other methods should be avoided as complications can occur.
reverse. 1  opposite or contrary in position, direction, order, or character: an impression reverse to what was intended; in reverse sequence. 2  with the back or rear part toward the observer: the reverse side of a fabric.
A third means for creating the opposite of an adjective is to combine it with less or least to create a comparison which points in the opposite direction. Interesting shades of meaning and tone become available with this usage.