neurofibrillary tangle. noun. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of nerve cells of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.weet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.
Personal life. Stephens was born in Plantation, Florida to Sybil Smith (who, in 1988 as a swimmer at Boston University, became the first African-American female to be named First Team All-American in Division I history) and John Stephens, a professional American football player.
Stephen Edward Ambrose (January 10, 1936 â October 13, 2002) was an American historian and biographer of U.S. Presidents Dwight D. Eisenhower and Richard Nixon.He was a longtime professor of history at the University of New Orleans and the author of many best selling volumes of American popular history.mbrose's earliest works concerned the Civil War. He wrote biographies of the generals Emory Upton and Henry Halleck, the first of which was based on his dissertation. Early in his career, Ambrose was mentored by World War II historian Forrest Pogue.