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Lorraine Day, M.D. What is Mad Cow Disease? Mad Cow Disease is the common term for Bovine Spongiform Encepholopathy (BSE), a progressive neurological disorder of cattle which can be transmitted to other species, including humans. In humans, it is called Creutzfeldt-Jakob Disease, after the two doctors who first described the symptoms of the disease.
Mad cow disease is an infectious disease caused by prions that affect the brains of cattle. The actual name of the disease is bovine spongiform encephalopathy (BSE), a name that refers to the changes seen in brain tissue of affected cows.nfection leads to tiny holes in parts of the brain, giving the tissue a sponge-like appearance when viewed with a microscope. These so-called spongy holes cause slow deterioration within the cow's brain and eventually other symptoms develop affecting the whole body. Death follows.