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Pathophysiology of COPD. COPD is a complex syndrome comprised of airway inflammation, mucociliary dysfunction and consequent airway structural changes.1. Airway inflammation. COPD is characterized by chronic inflammation of the airways, lung tissue and pulmonary blood vessels as a result of exposure to inhaled irritants such as tobacco smoke.
The reference to a complication or comorbid condition does not imply that improper or inadequate care has been provided. For example, a patient admitted to the hospital for treatment of an exacerbation of COPD would assign to one of three MS-DRGs for COPD as follows: