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Pancreatitis caused by gallstones. Pancreatitis caused by gallstones Gallstones are a common cause of pancreatitis. Gallstones, produced in the gallbladder, can block the bile duct, stopping pancreatic enzymes from traveling to the small intestine and forcing them back into the pancreas.
1 Gallstones and alcohol are common causes of acute pancreatitis. Other causes include high levels of fats in the blood, certain drugs, certain medical procedures, and some infections.  Chronic pancreatitis is inflammation that gets worse over time and leads to permanent damage in the pancreas. Heavy alcohol use is the most common cause. Other causes include heredity, cystic fibrosis, high levels of calcium or fats in the blood, certain medications, and some autoimmune conditions.