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It is the innermost part of the adrenal gland, consisting of cells that secrete epinephrine (adrenaline), norepinephrine (noradrenaline), and a small amount of dopamine in response to stimulation by sympathetic preganglionic neurons.he adrenal medulla consists of irregularly shaped cells grouped around blood vessels. These cells are intimately connected with the sympathetic division of the autonomic nervous system (ANS).
The two most important hormones of the adrenal medulla are the catecholamines. epinephrine and norepinephrine (Figure 1). The synthesis pathway for. norepinephrine is identical to that used by adrenergic neurons. However, the. adrenal medulla expresses an additional enzyme, phenylethanolamine-N-methyl-.