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You can use most sugar substitutes if you have diabetes, including: 1  Saccharin (Sweet'N Low) 2  Aspartame (NutraSweet, Equal) 3  Acesulfame potassium (Sunett)  Sucralose (Splenda)
Aspartame in diet sodas, or aspartame in other liquid form are absorbed more quickly and have been shown to spike plasma levels of aspartic acid. The exact mechanism of acute reactions to excess free glutamate and aspartate is currently being debated.