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Geriatric â In a study involving 24 healthy subjects, the mean elimination half-life of olanzapine was about 1.5 times greater in elderly (â¥65 years) than in nonelderly subjects (<65 years).
The half-life of Seroquel is about 6 hours. This means that in 6 hours, half of the dose is gone. In another 6 hours, half the remaining dose is gone, so your serum level is about down to 25. In 24 hours, you are down to about 6mg, which is probably negligible, and in 30 hours or so it will have cleared your system.