Telechelic polymer. A telechelic polymer or oligomer is a prepolymer capable of entering into further polymerization or other reactions through its reactive end-groups. It can be used for example to synthesize block copolymers. By definition, a telechelic polymer is a di-end-functional polymer where both ends possess the same functionality. Where the chain-ends of the polymer are not of the same functionality they are termed di-end-functional polymers.
The cause of Tay-Sachs disease is a genetic defect (mutation) that is passed from parent to child. This genetic defect is located in the HEXA gene, which is found on chromosome 15.The HEXA gene makes part of an enzyme called beta-hexosaminidase A, which plays a critical role in the nervous system.he cause of Tay-Sachs disease is a genetic defect (mutation) that is passed from parent to child. This genetic defect is located in the HEXA gene, which is found on chromosome 15.
Tay-Sachs disease-caused by mutations in the HEXA gene. More than 120 mutations that cause Tay-Sachs disease have been identified in the HEXA gene.These mutations reduce or eliminate the activity of the enzyme beta-hexosaminidase A, which prevents the enzyme from breaking down GM2 ganglioside.ay-Sachs disease-caused by mutations in the HEXA gene. More than 120 mutations that cause Tay-Sachs disease have been identified in the HEXA gene.