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You can use most sugar substitutes if you have diabetes, including: 1  Saccharin (Sweet'N Low) 2  Aspartame (NutraSweet, Equal) 3  Acesulfame potassium (Sunett)  Sucralose (Splenda)
Aspartame side effects According to the American Cancer Society, aspartame is approximately 200 times sweeter than sugar. So only a very small amount is needed to give food and beverages a sweet flavor.