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About Mitral Valve Prolapse & Regurgitation. A heart murmur that is most pronounced when the stethoscope is positioned at the heart's apex and occurs in the late systolic phase may be caused by mitral valve prolapse. This is also known as floppy valve syndrome. The murmur is normally preceded by a series of clicks.
The mitral valve regulates the flow of oxygen rich blood from the lungs to pass from the left atrium to the left ventricle.There are two main diseases or malfunctions of heart valves: regurgitation (valve does not close tightly) and stenosis (valve does not open fully).itral Valve Regurgitation, Stenosis, and Prolapse. The mitral valve is referred to as atrioventricular valves because it is located between the left atria and the left ventricle.