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Antibiotics can take two to three weeks to leave your system. They seem to work overtime to clean up your system even after you stop taking the pills. Also, some antibiotics work longer or shorter depending on the kind. For instance, Neomycin, is not completely absorbed into the blood system and is excreted out through urine and fecal matter. In this case, it is only in the system for 4-5 days.
0. 1. How long antibiotics stay in your system after you finish taking them totally depends upon the antibiotic the person is taking, doses, and the person`s metabolism as well.Generally antibiotics should stay for a week in the system after you finish taking them.jack Perry.. 1. How long antibiotics stay in your system after you finish taking them totally depends upon the antibiotic the person is taking, doses, and the person`s metabolism as well.Generally antibiotics should stay for a week in the system after you finish taking them.