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In addition, evidence on their combined effect on all-cause mortality is conflicting (17, 18). To address the interaction of obesity and OSA, we used a large historical cohort of patients with suspected OSA and investigated whether obesity influences the effect of nocturnal hypoxemia on cardiovascular events.
Recent research shows that in some cases, certain genetic factors may cause the changes in appetite and fat metabolism that lead to obesity. For a person who is genetically prone to weight gain (e.g., has a lower metabolism) and who leads an inactive and unhealthy lifestyle, the risk of becoming obese is high.