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Obesity hypoventilation (HI-po-ven-tih-LA-shun) syndrome (OHS) is a breathing disorder that affects some obese people. In OHS, poor breathing results in too much carbon dioxide (hypoventilation) and too little oxygen in the blood (hypoxemia). OHS sometimes is called Pickwickian syndrome. To understand OHS, it helps to understand how the lungs work.
The causes of both environmental and tissue hypoxia often result in the intermediate state of hypoxemia; thus the causes of any type of hypoxia are also potential causes of hypoxemia. Some of the many causes of hypoxia are the following: 1  Chemical or gas poisoning (for example cyanide, carbon monoxide)  Low or absent concentration of oxygen (for example, high altitudes reached without supplemental oxygen as seen in mountain climbing, and aviation, drowning or fires)