The names of some man-made satellites are Sputnik 1, Explorer 1, the International Space Station, ORBCOMM FM-107, Gonets-19 and SES-8. In 1957, Russia launched the first man-made satellite called Sputnik 1, and the United States sent Explorer 1 into orbit in 1958.
Many medications have been implicated in pedal edema, especially vasodilators, estrogens, NSAIDs, and calcium channel blockers. Dihydropyridine drugs are more likely than other calcium channel blockers to cause pedal edema.
NSAIDs can also exacerbate chronic urticaria, and usually, if one such drug does so, they all will. The exact mechanism underlying this phenomenon is unknown. However, since your friend seems to be able to tolerate all NSAIDs tried to date with the exception of ibuprofen, I would rule out the possibility of sensitivity to the entire class of these drugs. Finally, anaphylaxis and acute urticaria (generated de novo) can occur with NSAID administration.