Telechelic polymer. A telechelic polymer or oligomer is a prepolymer capable of entering into further polymerization or other reactions through its reactive end-groups. It can be used for example to synthesize block copolymers. By definition, a telechelic polymer is a di-end-functional polymer where both ends possess the same functionality. Where the chain-ends of the polymer are not of the same functionality they are termed di-end-functional polymers.
The cause of Tay-Sachs disease is a genetic defect (mutation) that is passed from parent to child. This genetic defect is located in the HEXA gene, which is found on chromosome 15.The HEXA gene makes part of an enzyme called beta-hexosaminidase A, which plays a critical role in the nervous system.he cause of Tay-Sachs disease is a genetic defect (mutation) that is passed from parent to child. This genetic defect is located in the HEXA gene, which is found on chromosome 15.
Tay-Sachs disease is a rare disorder passed from parents to child. In the most common form, a baby about 6 months old will begin to show symptoms. Tay-Sachs disease results when an enzyme that helps break down fatty substances is absent. These fatty substances build up to toxic levels in the child's brain and affect the nerve cells. As the disease progresses, the child's body loses function, leading to blindness, deafness, paralysis and death. There is no cure for Tay-Sachs disease. Gene therapy or enzyme replacement therapy research may eventually lead to a cure or treatment to slow the progression of Tay-Sachs disease.