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In the prokaryotic bacterium E. coli, replication can occur at a rate of 1,000 nucleotides per second. In comparison, eukaryotic human DNA replicates at a rate of 50 nucleotides per second. In both cases, replication occurs so quickly because multiple polymerases can synthesize two new strands at the same time by using each unwound strand from the original DNA double helix as a template.
DNA is found in the chromosomes of the nucleus in a cell and it carries hereditary information. RNA is located in the cell but not in the nucleus. Just as proteins consist of long chains of amino acids, DNA and RNA consists of nucleic acid chains called nucleotides. Nucleotides are composed of three units: base, sugar (monosaccharide) and phosphate. Bases are found in both DNA and RNA. As seen below, they are adenine, cytosine, guanine, thymine, and uracil.