The frontal lobe contains most of the dopamine-sensitive neurons in the cerebral cortex. The dopamine system is associated with reward, attention, short-term memory tasks, planning, and motivation. Dopamine tends to limit and select sensory information arriving from the thalamus to the forebrain.
Na + concentration is lowered, indicating that Na + in-flux is responsible for the rising phase of the action po-tential. Their data also suggested that the falling phaseof the action potential was caused by a later increase inK+ permeability.
5-HT2A receptor Edit. Hallucinogens like LSD, mescaline and psilocybin act as 5-HT 2A agonists, and action at this receptor is thought to be primarily responsible for their hallucinogenic effects (although the 5-HT 1A and 5-HT 2C receptors are also involved to a lesser extent).