The names of some man-made satellites are Sputnik 1, Explorer 1, the International Space Station, ORBCOMM FM-107, Gonets-19 and SES-8. In 1957, Russia launched the first man-made satellite called Sputnik 1, and the United States sent Explorer 1 into orbit in 1958.
Many medications have been implicated in pedal edema, especially vasodilators, estrogens, NSAIDs, and calcium channel blockers. Dihydropyridine drugs are more likely than other calcium channel blockers to cause pedal edema.
Usually, we run to the medicine cabinet for a supposedly harmless over the counter headache reliever, usually a NSAID (nonsteroidal anti-inflammatory drugs) like aspirin, ibuprofen and naproxen. But most of us are unaware that NSAIDS may cause ulcers, bleeding, or holes in the stomach or intestine.