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Home > Health A â Z > Psychosis. A severe mental disorder in which a person loses the ability to recognize reality or relate to others. Symptoms include being paranoid, having false ideas about what is taking place or who one is, and seeing, hearing, or feeling things that are not there. PubMed Health Glossary.
Medical Definition of Psychosis. Psychosis: In the general sense, a mental illness that markedly interferes with a person's capacity to meet life's everyday demands. In a specific sense, it refers to a thought disorder in which reality testing is grossly impaired.