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In addition, evidence on their combined effect on all-cause mortality is conflicting (17, 18). To address the interaction of obesity and OSA, we used a large historical cohort of patients with suspected OSA and investigated whether obesity influences the effect of nocturnal hypoxemia on cardiovascular events.
Obesity can sometimes be traced to a medical cause, such as Prader-Willi syndrome, Cushing's syndrome, and other diseases and conditions. However, these disorders are rare and, in general, the principal causes of obesity are:1  Inactivity. 2  If you're not very active, you don't burn as many calories.3  With a sedentary lifestyle, you can easily take in more calories every day than you use through exercise and normal daily activities.besity can sometimes be traced to a medical cause, such as Prader-Willi syndrome, Cushing's syndrome, and other diseases and conditions. However, these disorders are rare and, in general, the principal causes of obesity are: