ATP Synthase is the terminal step of oxidative phosphorylation (cellular respiration). Complexes I, II, III, and IV take electrons from NADH or FADH(2) and transfer them to O2 to form H2O. During this process protons (H+) are pumped out of the mitochondrial matrix into the outer mitochondrial space. The proton gradient that is formed as a result of this pumping action is what drives ATP synthase to favor the formation of ATP from ADP plus phosphate. The transfer of electrons to O2 is coupled to the formation of ATP such that if there is no ADP and phosphate, the rate of respiration dramatically decreases.
GENERAL. 1  The Giant Maso Mastiff is a new and still a developing breed that is being developed with the aim to produce a healthier version of Old English Mastiff dog that can live longer. Originating in Germany, these dogs have more English Mastiff in them than the other parent breed, the Cane Corso Itliano.
The mastiff is also one of the most powerful dog in the world. My friends mastiff Abraham  was the top weight pull dog in North America in 2004 PULLING 7300 POUNDS. The Old English Mastiff is the LARGEST breed of dog in the world..They can weigh anywhere from 110 pounds to the 343 pounds. Zorba,an English mastiff ,held the world record of the world's largest dog. Although most Mastiff males weigh around 160-230 pounds and females around 120-190 pounds.The height of a mastiff can range from 25 inches at the shoulder to 36 inches.s a Mastiff breeder, our kennel produces quality puppies. WHAT IS THE LARGEST BIGGEST HEAVIEST BREED OF DOG IN THE WORLD. The Old English Mastiff is the LARGEST breed of dog in the world.