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About Mitral Valve Prolapse & Regurgitation. A heart murmur that is most pronounced when the stethoscope is positioned at the heart's apex and occurs in the late systolic phase may be caused by mitral valve prolapse. This is also known as floppy valve syndrome. The murmur is normally preceded by a series of clicks.
In brief: Left side. The mitral valve separates the left atrium (receives blood from the lungs) from the left ventricle (main pumping chamber that pumps to the body generating the blood pressure). In brief: Left side. The mitral valve is located on the left side of the heart, between the left atrium and the left ventricle.  The mitral valve is located on the left side of the heart, between the left atrium and the left ventricle.