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Many times, people are not aware they have colon polyps because there are no symptoms. Larger growths can bleed, causing blood in the stool. Sometimes bleeding polyps can cause fatigue and other symptoms of anemia (low levels of red blood cells). On rare occasions, a large polyp can cause diarrhea or secretion of large amounts of potassium. This can cause marked fatigue and muscle weakness.
Appointments & care. At Mayo Clinic, we take the time to listen, to find answers and to provide you the best care. Familial adenomatous polyposis (FAP) is a rare, inherited condition that causes extra tissue (polyps) to form in your large intestine (colon) and rectum.Polyps can also occur in the upper gastrointestinal tract, especially the upper part of your small intestine (duodenum).amilial adenomatous polyposis can cause other complications: 1  Duodenal polyps. 2  These polyps grow in the upper part of your small intestine and may become cancerous. 3  But with careful monitoring, duodenal polyps can often be detected and removed before cancer develops. 4  Periampullary polyps.