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Pancreatitis caused by gallstones. Pancreatitis caused by gallstones Gallstones are a common cause of pancreatitis. Gallstones, produced in the gallbladder, can block the bile duct, stopping pancreatic enzymes from traveling to the small intestine and forcing them back into the pancreas.
One of the most common causes of acute pancreatitis is gallstones. Gallstones that escape from the gallbladder can block the pancreatic duct. (The pancreatic duct delivers digestive enzymes from the pancreas to the small intestine.) When the pancreatic duct becomes blocked, enzymes can't flow properly.