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A: Prednisone is a corticosteroid medication which is used to treat various inflammatory conditions including temporary use for relief of allergic reactions. Side effects associated with short term use of prednisone include insomnia, stomach upset, mood changes, increased appetite, and weight gain.
The longer the prednisone was taken and the higher the dose, the longer it will take to taper down and stop it. The body itself produces a substance that is equivalent to about 5 mg of prednisone. A short course of 10 mg of prednisone a day may not cause side effects. However, either a dosage of 10 to 20 mg a day for a month or moreâor a dosage of more than 20 mg a day for any length of timeâcould cause some adverse effects. As the prednisone dosage is tapered down below 10 mg a day and eventually discontinued, the temporary side effects will lessen and reverse.