A number of non-infectious causes can result in diarrhea. These include lactose intolerance, irritable bowel syndrome, non-celiac gluten sensitivity, celiac disease, inflammatory bowel disease, hyperthyroidism, and a number of medications. In most cases, stool cultures to confirm the exact cause are not required.
Most dogs are first bred between the 10th and 14th day after the onset of proestrus. As long as the bitch will accept the male, mating every other day for a total of two or three matings is generally considered sufficient. However, signs of proestrus are not obvious in some bitches.
The breeding gets on a 5 min cooldown and the cub starts his 20min journey to maturity. By the time your first cub reaches maturity and is also able to mate you have an additional 3 cubs maturing in 5 - 10 and 15 minutes. So after just 25 minutes you have a second pair of animals which you can breed.This wil double your breeding rate and nog have 2 cubs every 5 minutes. This takes 20 minutes to get effect as for the produced cubs take 20 minutes to reach maturity.In about 1 hour you have around 14 mature animals and around 10 cubs.s stated below on the minecraft wiki about breeding. Breeding has a 5 minute cooldown before they can be bred again. Each animal which is fed its food will enter love mode, preparing to breed with another animal in love mode.