Insulin glargine has a substitution of glycine for asparagine at N21 (Asn21) and two arginines added to the carboxy terminal of B chain. The arginine amino acids shifts the isoelectric point from a pH of 5.4 to 6.7, making the molecule more soluble at an acidic pH and less soluble at physiological pH.
If you have money in other employer's plans, you may be able to transfer or roll it over to the The Pennsylvania State University retirement plan to increase your maximum loan amount. This is only if the The Pennsylvania State University retirement plan accepts rollovers.
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