You may be able to treat iron deficiency and decrease RLS symptoms by eating more iron-rich foods, such as: red meat; liver; spinach and other dark leafy greens; dried fruit; poultry; pork; seafood; iron-fortified cereals; beans; Eating foods rich in vitamin C along with iron-rich foods can help your body absorb iron better.
Parathyroid hormone (PTH) stimulates uptake of calcium into the bones (1) (and therefore osteoblast apoptosis (2)) and deportation of calcium from the bones (23), and inhibits excretion of calcium, generally increasing a low blood-calcium level. Low levels of PTH prevent bone loss.
Pathogenesis of the Increased Osteoclast Activity in Myeloma The adherence of abnormal myeloma cells in the bone marrow stromal cells (BMSCs), through the binding of VCAM-1 on stromal cells and Î±4Î²1 integrin on MM cells, leads to the upregulation of a broad spectrum of factors that stimulate osteoclast formation, differentiation and activity, as well as suppression of negative regulators of osteoclastogenesis.