Also, be sure to see the Game of Thrones Characters chart, here. Below is a simpler chart focusing only on the four main families. It primarily shows the royal bloodline with all the claimants and possible claimants, including popular fan theories (SPOILERS!). Click it to enlarge.
Other drugs, known as prodrugs, are activated by the action of CYP2D6. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver.
Metabolism. Fluticasone propionate is metabolized in the liver by cytochrome P450 3A4-mediated hydrolysis of the 5-fluoromethyl carbothioate grouping. This transformation occurs in 1 metabolic step to produce the inactive 17-(beta)-carboxylic acid metabolite, the only known metabolite detected in man.