The skin involvement of dermatomyositis is absent in polymyositis. Dysphagia (difficulty swallowing) or other problems with esophageal motility occur in as many as 1/3 of patients. Low grade fever and peripheral adenopathy may be present.
In 1524, Michelangelo was commissioned by the Medici pope to design the library for the San Lorenzoâs Church in Florence, Italy. Michelangelo designed both the interior of the library itself and its vestibule. He pioneered the Mannerist style in his design of the library which became renowned for its architecture. The Laurentian Library is one of Michelangeloâs most important architectural achievements and his innovations and use of space in the library were revolutionary.
The Most Important Building in the World. This is what the people of Florence might have called the Duomo Cathedral in the 1400s. To them, it probably was the most important building in the world. Instead of competing with other major cities through football games, Italian cities tried to outdo each other's buildings. Whoever had the best buildings, won.