The skin involvement of dermatomyositis is absent in polymyositis. Dysphagia (difficulty swallowing) or other problems with esophageal motility occur in as many as 1/3 of patients. Low grade fever and peripheral adenopathy may be present.
In 1524, Michelangelo was commissioned by the Medici pope to design the library for the San Lorenzoâs Church in Florence, Italy. Michelangelo designed both the interior of the library itself and its vestibule. He pioneered the Mannerist style in his design of the library which became renowned for its architecture. The Laurentian Library is one of Michelangeloâs most important architectural achievements and his innovations and use of space in the library were revolutionary.
There are stairs at the end that take you down to the Oficina de Turismo ColÃ³n. The tourist office was designed by Portuguese architect, Alvaro Siza, who worked with Spaniards, Juan Miguel Hernandez de Leon and Carlos Riano. Below the Plaza de ColÃ³n there was an ancient subterranean passage.