MTHFR C677T Mutation Basics. The MTHFR C677T mutation affects the enzyme methylenetetrahydrofolate reductase, which is the rate-limiting enzyme in the formation of 5-methyltetraydrofolate (5-MTHF), or methylfolate.If you have the C677T mutation, your ability to convert folic acid into methylfolate is significantly reduced.olate found naturally in foods, such as leafy green vegetables, does not pose a problem.The MTHFR C677T mutation may also cause high homocysteine levels, as methylfolate plays an important role in homocysteine metabolism. Elevated homocysteine levels can cause oxidative stress and increase your risk of heart disease.
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Rotating abrasive wheel on a bench grinder. 8 in (200 mm) wire brush mounted to bench grinder (tool rest in foreground). A bench grinder is a benchtop type of grinding machine used to drive abrasive wheels. A pedestal grinder is a similar or larger version of grinder that is mounted on a pedestal, which may be bolted to the floor or may sit on rubber feet.