Also, be sure to see the Game of Thrones Characters chart, here. Below is a simpler chart focusing only on the four main families. It primarily shows the royal bloodline with all the claimants and possible claimants, including popular fan theories (SPOILERS!). Click it to enlarge.
Other drugs, known as prodrugs, are activated by the action of CYP2D6. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver.
Tamoxifen is a drug that binds to your estrogen receptors. Therefore it was thought that it could prevent excess estrogen binding, hence halting cancer from forming. It is generally prescribed to high-risk women to prevent breast cancer, and is usually taken for five years. However, Tamoxifen has been found to cause cancer instead. According to a study published in the International Journal of Gynecological Cancer, the treatment of breast cancer with tamoxifen results in an increased risk of uterine cancer incidence and mortality.