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Glycolysis is a series of reactions that and extract energy from glucose by splitting it into two three-carbon molecules called pyruvates. Glycolysis is an ancient metabolic pathway, meaning that it evolved long ago, and it is found in the great majority of organisms alive today2,3^{2,3}â2,3ââstart superscript, 2, comma, 3, end superscript. In organisms that perform cellular respiration, glycolysis is the first stage of this process. However, glycolysis doesnât require oxygen, and many anaerobic organismsâorganisms that do not use oxygenâalso have this pathway.
Glycolysis produces energy in the form of ATP and NADH. The glycolytic pathway consists of 10 enzyme-catalyzed steps. During glycolysis, glucose, a six-carbon carbohydrate, is oxidized to form two molecules of pyruvate, a three-carbon molecule.For each glucose molecule metabolized, the pathway produces two molecules of ATP and two molecules of NADH.Glycolysis is not isolated from other metabolic pathways.or example, the product of glycogen breakdown, glucose-6-phosphate, can enter the glycolytic pathway at the second step. Glyceraldehyde-3-phosphate, which is produced by photosynthesis, is also a glycolytic intermediate, so it can be directed from this anabolic pathway into glycolysis when energy is needed.