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The DEPO will stay in your system for 3 months but you can become pregnant and conceive, before the 3 month time frame is up. One in a 100 women getting a Depo shot every 12 weeks will get pregnant in a year. After stopping it takes on average a further 9-10 months to get pregnant.he DEPO will stay in your system for 3 months but you can become pregnant and conceive, before the 3 month time frame is up. One in a 100 women getting a Depo shot every 12 weeks will get pregnant in a year. After stopping it takes on average a further 9-10 months to get pregnant.
The absence of periods is not harmful, and periods usually return to normal after Depo-Provera is stopped. If unusually heavy or continuous bleeding occurs, you should see your doctor. Other possible side effects include weight gain, headaches, nervousness, abdominal discomfort, dizziness and weakness or fatigue.o. Depo-Provera only works for about 3 months. The shot must be repeated every 3 months to prevent pregnancy. After a woman stops using Depo-Provera, her normal ovarian function returns after a short time. However, it takes an average of 9 to 10 months to get pregnant after getting the last shot.