Erythema multiforme (EM) is a skin reaction that comes from an infection or another trigger. EM is a type of allergic reaction. In most cases, it occurs in response to an infection. In rare cases, it is caused by certain medicines or body-wide (systemic) illness. Infections that may lead to EM include:
The most common causes of sudden (acute) aortic valve regurgitation include: 1  Endocarditis, which is an infection in the heart. 2  Aortic dissection, which means that the inner layer of the aorta separates from the middle layer. 3  Problems with a replacement (artificial) aortic valve.  Trauma to the heart valve or aorta.
Regurgitation is the name for leaking heart valves. Sometimes the condition is minor and may not require treatment, but other times valve regurgitation places a strain on the heart. It can cause the heart to work harder to pump the same amount of blood.Regurgitation occurs when:egurgitation is the name for leaking heart valves. Sometimes the condition is minor and may not require treatment, but other times valve regurgitation places a strain on the heart. It can cause the heart to work harder to pump the same amount of blood. Regurgitation occurs when: