Self-actualization, according to Maslow, represents the growth of an individual toward fulfillment of the highest needs. Maslow argues that only high acheivers are self-actualizers, but we are all in fact capable of self-actualization.
In a thrombotic stroke, a blood clot (thrombus) forms inside one of the brain's arteries. The clot blocks blood flow to a part of the brain. This causes brain cells in that area to stop functioning and die quickly.
Any device inserted into the vascular system increases the risk of thrombus formation, either in the vessel or in the catheter. The 3 primary causes of thrombus formation in a vessel are known as the Triad of Virchow. The first cause is alteration of the vein wall by injury, irritation, or disease process. Vein irritation can occur during PICC insertion or when the vessel is too small to accommodate the diameter of the PICC. A PICC that is too large will abrade the intima of the vein into which it has been inserted.