Similar results have been found in other studies [17] [18]. Based on these reports we have defined hard-to-heal ulcers in this study as venous leg ulcers with an initial area of 10cm2 or greater and a duration of six months or more.
A gene is a segment of DNA containing the code used to synthesize a protein. A chromosome contains hundreds to thousands of genes. Every human cell contains 23 pairs of chromosomes, for a total of 46 chromosomes. A trait is any gene-determined characteristic and is often determined by more than one gene. Some traits are caused by abnormal genes that are inherited or that are the result of a new mutation.
Body cells have pairs of chromosomes while sex cells have only single sets of chromosomes. The human body cells have 22 pairs of autosomes and 1 pair of sex chromosomes for a total of 23 pairs or 46 chromosomes. But sex cells (sperm or ovum, known as gametes or diploid cells) contain only 23 chromosomes (unpaired), when they meet (forming a Zygote), the 23 from each male and female gamete form a cell containing 46 chromosomes to make a Haploid cell. Normal body cells (known as a haploid cells) contain 46 chromosomes (or 23 pairs of chromosomes).