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This is the third form of hypersensitivity in the Gell-Coombs classification, called Type III hypersensitivity. Immune complex deposition is a prominent feature of several autoimmune diseases, including systemic lupus erythematosus, cryoglobulinemia, rheumatoid arthritis, scleroderma and SjÃ¶gren's syndrome.
The incidence of rheumatoid arthritis is predicted by rheumatoid factor titer in a longitudinal population study. del Puente A(1), Knowler WC, Pettitt DJ, Bennett PH. Author information: (1)National Institute of Arthritis and Musculoskeletal and Skin Diseases, Phoenix, Arizona 85014.he incidence of rheumatoid arthritis is predicted by rheumatoid factor titer in a longitudinal population study. del Puente A(1), Knowler WC, Pettitt DJ, Bennett PH. Author information: (1)National Institute of Arthritis and Musculoskeletal and Skin Diseases, Phoenix, Arizona 85014.