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Tobacco would be the salvation not only of Jamestown but of the  state of Virginia. Tobacco remain a profitable case crop in the  region until the negative campaign against â¦the tobacco industry  decreased the demand.
Jamestown was successful because they grew tobacco and that made them a lot of money, which led to many people buying tobacco. Tobacco is a cash crop, so obviously the people â¦ in Jamestown made a lot of money. 7 people found this useful.hat made Jamestown the first successful colony? In 1692, a settler named John Rolfe began growing a new type of tobacco using seed from West Indies then smoking soon became popular in England, and the Jamestown colonists fo â¦ und that they could sell as much Tabasco a s could be produced.