Postgraduate programs are getting a lot more practical with hands-on learning and job-focused training. By Christopher J. Gearon, Contributor | March 13, 2013, at 8:30 a.m. Focus on Job Skills With a Professional Master's Degree.
PARK2 (OMIM *602544) is the parkin gene that may cause a form of autosomal recessive juvenile Parkinson disease (OMIM 600116) due to a mutation in the parkin protein. This form of genetic mutation may be one of the most common known genetic causes of early-onset Parkinson disease.In one study of patients with onset of Parkinson disease prior to age 40 (10% of all PD patients), 18% had parkin mutations, with 5% homozygous mutations.his form of genetic mutation may be one of the most common known genetic causes of early-onset Parkinson disease. In one study of patients with onset of Parkinson disease prior to age 40 (10% of all PD patients), 18% had parkin mutations, with 5% homozygous mutations.
Background & Aims: The NOD2 gene, which is strongly associated with susceptibility to Crohnâs disease (CD) of the terminal ileum, interacts with bacterial lipopolysaccharide (LPS), inducing cellular activation.aneth cells detect and respond to bacteria, and the NOD2 protein may mediate their interaction with bacterial products. Inherited mutations in the NOD2 gene therefore may abrogate the appropriate responses of Paneth cells, and instead promote a maladaptive pro-inflammatory response.