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Definition of Epigenetic. Epigenetic: Something that affects a cell, organ or individual without directly affecting its DNA. An epigenetic change may indirectly influence the expression of the genome. See also: Epigenetics. From epi- meaning, in this context, after or beside + genetic.
Epigenetics: Fundamentals. What is Epigenetics? Epigenetics is the study of potentially heritable changes in gene expression (active versus inactive genes) that does not involve changes to the underlying DNA sequence â a change in phenotype without a change in genotype â which in turn affects how cells read the genes.