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An underactive thyroid gland, a disorder called hypothyroidism, would cause a sensation of lump in the throat. General enlargement, nodules and inflammation in the thyroid gland can be caused by both hypo as well as hyperthyroidism. These nodules can cause a feeling of lump in the throat. Diagnosis usually rests on physical examination, blood tests, a needle biopsy and possibly an ultra sound examination.
Synthroid and shrinking Thyroid Lumps. I have a question I'm sure you've been asked many times. During my annual check up my Dr. found a lump on the left side of my throat. I was sent for an ultrasound which determined a solid lump. At which time I was sent for a biopsy which turned out to be non-cancerous.