Gem for OneNote is a powerful toolkit designed to provide users with expanded functionality in OneNote 2010 and OneNote 2013. It is installed as an add-in for the Microsoft application and delivers over 150 new features to users, all of which are grouped together into six new tabs.
Protease inhibitors (PIs) are a class of antiviral drugs that are widely used to treat HIV/AIDS and hepatitis caused by hepatitis C virus.iven the specificity of the target of these drugs there is the risk, as in antibiotics, of the development of drug-resistant mutated viruses. To reduce this risk it is common to use several different drugs together that are each aimed at different targets.
Without the reverse transcriptase enzyme, the virus HIV cannot make DNA copies of its genetic material (i.e. , the RNA), because the activation energy for the uncatalyzed reaction is too large. The DNA copy is essential for the virus to take over the infected cell's machinery and produce new copies of itself.his class of drug acts by inhibiting protease, the enzyme required by HIV to cut its protein into the proper segments to assemble new viral particles. Protease inhibitors, used in combination with two reverse transcriptase inhibitors, have proven to be quite successful.