Tweet. There are no known adverse reactions between Plavix (Clopidogrel) and eating grapefruit, or drinking grapefruit juice. Furthermore, there is no sufficient evidence that illustrates grapefruit juice, or the fruit itself would interfere with the effectiveness of Plavix.
Other, more minor side effects include constipation, headache, dry mouth and insomnia (because the chemicals in these drugs also influence sleep patterns). Herbal diet pills, even though they're all natural, can have potentially dangerous side effects depending upon their ingredients.
Other effects of mixing alcohol and sleeping pills include:3,4,5. 1  Drowsiness. 2  Dizziness/disorientation. 3  Impaired motor control. 4  Memory problems. 5  Slowed heart rate. 6  Slowed or difficulty breathing. 7  Lowered blood pressure. 8  Unusual behavior. 9  Increased risk of overdose. 10  Death.