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Heart failure can be ongoing (chronic), or your condition may start suddenly (acute). Heart failure signs and symptoms may include: 1  Shortness of breath (dyspnea) when you exert yourself or when you lie down. 2  Fatigue and weakness. 3  Swelling (edema) in your legs, ankles and feet. 4  Rapid or irregular heartbeat. 5  Reduced ability to exercise. 6  Persistent cough or wheezing with white or pink blood-tinged phlegm.
Heart and Lung Transplant Symptoms. Heart failure occurs when your heart is not able to pump enough blood to the tissues of your body. One of the first symptoms you will notice is shortness of breath. 1  Initially, shortness of breath occurs only with vigorous exertion or strenuous exercise.