In sickle cell disease, red blood cells are produced but then become deformed into the sickle shape, which causes red blood cells to lose their oxygen carrying capacity. The body subsequently becomes dehydrated, or with a fever.
some bipolar depression symptoms are the same as major depression symptoms persistent sadness feelings of hopelessness worthlessness and helplessness loss of interest in activities or hobbies once pleasurable including sex
Some of the following have been found to trigger bipolar symptoms from depression to mania: 1  Substance abuse. 2  Stress. 3  Hormonal imbalances. 4  Divorce, loss of a job, or other devastating life impacts. 5  Antidepressant medications. 6  Excessive caffeine. 7  Excessive medications.