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This is the third form of hypersensitivity in the Gell-Coombs classification, called Type III hypersensitivity. Immune complex deposition is a prominent feature of several autoimmune diseases, including systemic lupus erythematosus, cryoglobulinemia, rheumatoid arthritis, scleroderma and SjÃ¶gren's syndrome.
Five types of hypersensitivity reactions have been described: types I, II, III and V depend on antigen antibody interactions and have been termed âimmediateâ and type IV reactions depend on interaction of antigen with T lymphocytes and has been called âdelayedâtype hypersensitivityâ, or DTH.ive types of hypersensitivity reactions have been described: types I, II, III and V depend on antigen antibody interactions and have been termed âimmediateâ and type IV reactions depend on interaction of antigen with T lymphocytes and has been called âdelayedâtype hypersensitivityâ, or DTH.