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A: Prednisone is a corticosteroid medication which is used to treat various inflammatory conditions including temporary use for relief of allergic reactions. Side effects associated with short term use of prednisone include insomnia, stomach upset, mood changes, increased appetite, and weight gain.
1 Weakness: Weakness and fatigue is the most common prednisone withdrawal symptom. 2  One may feel extremely weak if prednisone is abruptly stopped. 3  Abdominal Pain: Frequent abdominal pain or a burning sensation is one of the withdrawal symptoms. 4  Weight Loss: There is a rapid weight loss which may lead to extreme fatigue.rednisone is a well-known steroid known as 'corticosteroid' in medical terms, which is prescribed for various diseases. Sudden stoppage of this steroid can lead to prednisone withdrawal symptoms.