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Malaria - and its cousin, yellow fever - had significant implications during the war and the debilitating consequences of the disease were already certain before the Civil War had started in earnest and well before its final history had been written.
Epidemiology of Yellow Fever and Malaria. By 1904, medical researchers had established that yellow fever and malaria were mosquito-borne diseases. In Cuba, the Walter Reed Commission confirmed Carlos Finlayâs hypothesis and proved that the mosquito of the genus Aedes transmits yellow fever.pidemiology of Yellow Fever and Malaria. By 1904, medical researchers had established that yellow fever and malaria were mosquito-borne diseases. In Cuba, the Walter Reed Commission confirmed Carlos Finlayâs hypothesis and proved that the mosquito of the genus Aedes transmits yellow fever.