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anophthalmos (anÂ´opthalÂ´mÉs), n a congenital absence of all tissues of the eyes. anophthalmia, anophthalmos. a developmental anomaly marked by complete absence of one or both eyes or the presence of rudimentary eyes. Occurs most commonly in pigs and sheep.
Parents that already have a child who suffers from anophthalmia has a 1 in 8 chance of having another child with anophthalmia. Approximately 2/3 of all cases of anophthalmia are determined to be of genetic basis.