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Thiazide Diuretics. Mechanism of Action: DIURETIC: Thiazides are sulfonamide related organic acids that are secreted into the proximal tubule by an organic secretory mechanism. (Thiazides compete for the same secretory process by which uric acid is secreted into the proximal tubule).
Most organic iodine compounds are in the -1 oxidation state. Most iodides are colorless or reddish-yellow and are weak reducing agents. +1 and +3 compounds are quite rare. They are both oxidizing agents. +1 compounds are found as iodine monochloride and hypoiodites. +3 compounds are found as iodine trichloride or iodine trifluoride. +5 compounds are found as iodates and iodic acid. Iodine pentafluoride and iodine pentoxide are iodine compounds in the +5 state.