Members of the DEWS Definition and Classification. Subcommittee developed a contemporary definition of dry eye disease and a three-. part classification system based on etiology, causative mechanisms and disease. severity.
Metaplasia. Definition: Metaplasia is the reversible replacement of one differentiated cell type with another differentiated cell type. Metaplasia causes precursor cells to change their cell fate, and do not change existing differentiated cells.he most common epithelial metaplasia is columnar to squamous (squamous metaplasia), as occurs in the respiratory tract in response to chronic irritation.
Pseudostratified columnar epithelium is a type of tissue that has a single layer of cells arranged in a fashion that appears to be stratified, whereas transitional epithelial tissue is an elastic-like epithelial tissue that swells, contracts, and changes shape as necessary.