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The DEPO will stay in your system for 3 months but you can become pregnant and conceive, before the 3 month time frame is up. One in a 100 women getting a Depo shot every 12 weeks will get pregnant in a year. After stopping it takes on average a further 9-10 months to get pregnant.he DEPO will stay in your system for 3 months but you can become pregnant and conceive, before the 3 month time frame is up. One in a 100 women getting a Depo shot every 12 weeks will get pregnant in a year. After stopping it takes on average a further 9-10 months to get pregnant.
Each injection gives you protection against pregnancy for 12 weeks. When you have the Depo-Provera injection within the first five days of your menstrual cycle, it works 24hrs after the injection. When you have the Depo-Provera injection after the first five days of your menstrual cycle, it works after 14 days. When the Depo-Provera injection is given to a woman after she has given birth, or had a miscarriage or an abortion, it works immediately. You can get Depo-Provera from your health care provider.