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Design of Experiments. Design of Experiments (DOE) is a study of the factors that the team has determined are the key process input variables (KPIV's) that are the source of the variation or have an influence on the mean of the output. A DOE (or set of DOE's) will help develop a prediction equation for the process in terms of Y = f(X1,X2,X3,X4,....Xn).
Independent variables are values that can be changed in a given equation or experiment. Think of an independent variable as your input. An independent variable represents information that you put in to the equation. Dependent variables are values that result directly from the independent variable.