Gem for OneNote is a powerful toolkit designed to provide users with expanded functionality in OneNote 2010 and OneNote 2013. It is installed as an add-in for the Microsoft application and delivers over 150 new features to users, all of which are grouped together into six new tabs.
Protease inhibitors (PIs) are a class of antiviral drugs that are widely used to treat HIV/AIDS and hepatitis caused by hepatitis C virus.iven the specificity of the target of these drugs there is the risk, as in antibiotics, of the development of drug-resistant mutated viruses. To reduce this risk it is common to use several different drugs together that are each aimed at different targets.
The binding of an inhibitor can stop a substrate from entering the enzyme's active site and/or hinder the enzyme from catalyzing its reaction. Inhibitor binding is either reversible or irreversible. Irreversible inhibitors usually react with the enzyme and change it chemically (e.g. via covalent bond formation).n enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.