Also, be sure to see the Game of Thrones Characters chart, here. Below is a simpler chart focusing only on the four main families. It primarily shows the royal bloodline with all the claimants and possible claimants, including popular fan theories (SPOILERS!). Click it to enlarge.
Other drugs, known as prodrugs, are activated by the action of CYP2D6. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver.
Except for the rifampin study, all reported drug interaction studies used a single 10-mg dose of rivaroxaban. Approximately 50% of rivaroxaban is metabolized (CYP3A4 [major pathway] and CYP2J2, based on in vitro studies), and approximately 40% of a dose is eliminated unchanged by the kidneys. Renal elimination is primarily by active renal secretion, perhaps via P-glycoprotein (P-gp) or breast cancer resistance protein.