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mirtazapine is a newer antidepressant that exhibits both noradrenergic and serotonergic activity it is at least as effective as the older antidepressants for treating mild to severe depressionsedation is the most common side effectirtazapine is a newer antidepressant that exhibits both noradrenergic and serotonergic activity it is at least as effective as the older antidepressants for treating mild to severe depression
Mirtazapine is a tetracyclic piperazinoazepine, which has a different structure from any other currently used antidepressant. It enhances central noradrenergic and serotonergic activity by blocking alpha 2 receptors and selectively antagonizing 5HT 2 and 5HT 3 receptors.