In sickle cell disease, red blood cells are produced but then become deformed into the sickle shape, which causes red blood cells to lose their oxygen carrying capacity. The body subsequently becomes dehydrated, or with a fever.
some bipolar depression symptoms are the same as major depression symptoms persistent sadness feelings of hopelessness worthlessness and helplessness loss of interest in activities or hobbies once pleasurable including sex
Bipolar depression is a prolonged state (at least 2 weeks at a time) of low energy levels and sadness or irritability. Symptoms of the bipolar depression may include a pessimistic attitude, social withdrawal, thoughts of death or suicide, extreme sadness, and irritability. Manic or depressive symptoms also sometime co-occur as part of the same episode.