Skin Cancer Foundation. http://visualsonline.cancer.gov/about.cfm. The ABCDEs of melanoma skin cancer are: 1  Asymmetry. One half doesn't match the appearance of the other half.  Border irregularity. The edges are ragged, notched, or blurred.
Effects of Hemolysis on Clinical Specimens. Hemolysis due to the breakdown of red blood cells is important to the laboratory because it can have an effect on laboratory results. The effects can be the result of products liberated from the red cells themselves, or due to interferences with laboratory analyzers.
Hemolysis refers to the destruction of red blood cells which leads to the release of haemoglobin from within the cells. Hemolysis affects specimen quality and, consequently, can affect the results for certain laboratory tests.Site personnel can prevent hemolysis by avoiding the circumstances that can cause it. These include: Too great a vacuum in the vein, causing the red cells to be drawn toward the bore of the needle too quickly. Make note of the Visit Type in the Visit Type section of the requisition (e.g. Visit 3 or Repeat of Week 9). 2  Use the checkboxes in the Test section of the requisition to indicate the test(s) to be performed based on the study-specific testing for the subjectâs actual visit.