Mutations in the VWF gene cause von Willebrand disease. The VWF gene provides instructions for making a blood clotting protein called von Willebrand factor, which is essential for the formation of blood clots.ype 3 is the most severe and rarest form of the condition. The four subtypes of type 2 von Willebrand disease are intermediate in severity. Another form of the disorder, acquired von Willebrand syndrome, is not caused by inherited gene mutations.
A vaporizer or vaporiser (a âvapeâ) is a device used to vaporize the active ingredients of plant material, commonly cannabis, tobacco, or other herbs or blends for the purpose of inhalation. However, they can also be filled with a mixture of propylene glycol, glycerin, and nicotine. (e.g. tobacco-free nicotine).
They're not hard to find. Stores selling them -- called vape shops -- are everywhere across the country. In the summer of 2016, new rules about their sale went into effect. So you have to be 18 to buy them and show an ID if you're under 27.