These studies are now being done by GWAS in 2 patient groups, examining both baseline HbF and the HbF response to hydroxyurea. Genetic modulation of sickle cell disease: Homozygosity for a single Î²-globin gene mutation (HBB; glu6val) causes sickle cell anemia.hese studies are now being done by GWAS in 2 patient groups, examining both baseline HbF and the HbF response to hydroxyurea. Genetic modulation of sickle cell disease: Homozygosity for a single Î²-globin gene mutation (HBB; glu6val) causes sickle cell anemia.
Spiral Galaxies. Spiral galaxy M100. Spiral galaxies have three main components: a bulge, disk, and halo (see right). The bulge is a spherical structure found in the center of the galaxy. This feature mostly contains older stars. The disk is made up of dust, gas, and younger stars. The disk forms arm structures.
The Large Magellanic Cloud. The Milky Way has a number of satellite galaxies, but the biggest one is the Large Magellanic Cloud. It is about 163,000 light-years away and around 1/100th the size of the Milky Way. Unlike our spiral galaxy, this one lacks a clean spiral shape. Some scientists think that is because the Milky Way and other galaxies are pulling and warping it. In terms of distance, there are two contenders for closest satellite galaxy. One group of stars is small enough that astronomers consider it a âdwarf galaxy.â