Tweet. There are no known adverse reactions between Plavix (Clopidogrel) and eating grapefruit, or drinking grapefruit juice. Furthermore, there is no sufficient evidence that illustrates grapefruit juice, or the fruit itself would interfere with the effectiveness of Plavix.
Other, more minor side effects include constipation, headache, dry mouth and insomnia (because the chemicals in these drugs also influence sleep patterns). Herbal diet pills, even though they're all natural, can have potentially dangerous side effects depending upon their ingredients.
Several things can affect who does and does not have a side effect when taking a drug â age, gender, allergies, how the body absorbs the drug, other drugs, vitamins and dietary supplements that you may be taking. Common side effects include upset stomach, dry mouth, and drowsiness.