Gem for OneNote is a powerful toolkit designed to provide users with expanded functionality in OneNote 2010 and OneNote 2013. It is installed as an add-in for the Microsoft application and delivers over 150 new features to users, all of which are grouped together into six new tabs.
Protease inhibitors (PIs) are a class of antiviral drugs that are widely used to treat HIV/AIDS and hepatitis caused by hepatitis C virus.iven the specificity of the target of these drugs there is the risk, as in antibiotics, of the development of drug-resistant mutated viruses. To reduce this risk it is common to use several different drugs together that are each aimed at different targets.
The structure of a protease (TEV protease) complexed with its peptide substrate in black with catalytic residues in red. (PDB: 1LVBâ) A protease (also called a peptidase or proteinase) is any enzyme that performs proteolysis; protein catabolism by hydrolysis of peptide bonds. Proteases have evolved multiple times, and different classes of protease can perform the same reaction by completely different catalytic mechanisms.