MTHFR C677T Mutation Basics. The MTHFR C677T mutation affects the enzyme methylenetetrahydrofolate reductase, which is the rate-limiting enzyme in the formation of 5-methyltetraydrofolate (5-MTHF), or methylfolate.If you have the C677T mutation, your ability to convert folic acid into methylfolate is significantly reduced.olate found naturally in foods, such as leafy green vegetables, does not pose a problem.The MTHFR C677T mutation may also cause high homocysteine levels, as methylfolate plays an important role in homocysteine metabolism. Elevated homocysteine levels can cause oxidative stress and increase your risk of heart disease.
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After that, you just have to work the spudger around releasing the rest of the clips, and the top will come off. The drive itself is held into the bottom part of the case by two plastic pegs that protrude slightly from the case into the screw holes of the drive on the side away from the USB plug.