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Full Definition of DIPHTHERIA. : an acute febrile contagious disease typically marked by the formation of a false membrane especially in the throat and caused by a gram-positive bacterium (Corynebacterium diphtheriae) that produces a toxin causing inflammation of the heart and nervous system.
Diphtheria. Diphtheria (dif-THEER-e-uh) is a serious bacterial infection usually affecting the mucous membranes of your nose and throat. Diphtheria typically causes a sore throat, fever, swollen glands and weakness.edications are available to treat diphtheria. However, in advanced stages, diphtheria can damage your heart, kidneys and nervous system. Even with treatment, diphtheria can be deadly â up to 3 percent of people who get diphtheria die of it. The rate is higher for children under 15.