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Because anencephaly is caused by abnormalities of the neural tube, it is classified as a neural tube defect. Because the neural tube fails to close properly, the developing brain and spinal cord are exposed to the amniotic fluid that surrounds the fetus in the womb.
Iron is needed to make red blood cells that transport oxygen to the baby, affecting the babyâs brain and body growth. 5. Folic acid deficiency â This leads to the babyâs neural tube being unable to close properly. The neural tube is the tissue from which the brain and spinal cord develop.he damage to the baby is possibly caused by increased stress hormone cortisol interfering with fetal development. 9. Motherâs mental state â A fetus is sensitive to and can be affected by the motherâs mental state. It is already preparing for life after birth based on the messages that the mom is providing.