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anophthalmos (anÂ´opthalÂ´mÉs), n a congenital absence of all tissues of the eyes. anophthalmia, anophthalmos. a developmental anomaly marked by complete absence of one or both eyes or the presence of rudimentary eyes. Occurs most commonly in pigs and sheep.
Phakomatoses (or neuro-oculo-cutaneous syndromes, neurocutaneous disorders) are multisystem disorders that have characteristic central nervous system, ocular, and cutaneous lesions of variable severity. The skin and the brain have a common ectodermal origin, so there are many genetic and acquired diseases that affect both tissues.