Similar results have been found in other studies [17] [18]. Based on these reports we have defined hard-to-heal ulcers in this study as venous leg ulcers with an initial area of 10cm2 or greater and a duration of six months or more.
A gene is a segment of DNA containing the code used to synthesize a protein. A chromosome contains hundreds to thousands of genes. Every human cell contains 23 pairs of chromosomes, for a total of 46 chromosomes. A trait is any gene-determined characteristic and is often determined by more than one gene. Some traits are caused by abnormal genes that are inherited or that are the result of a new mutation.
The nucleus of a cell contains chromosomes that carry genetic information. Most body cells have the same number of chromosomes, but this varies between species. Human body cells, for example, each have 23 matching pairs of chromosomes. Chromosomes are made from long, coiled molecules of DNA.