Jovian Planets. A Jovian planet is a gas giant, the term is derived from Jupiter which describes the three other gas giants in the Solar System as Jupiter-like.Though the name may imply it, a gas giant is not composed only of gas. Jovian planet is a gas giant, the term is derived from Jupiter which describes the three other gas giants in the Solar System as Jupiter-like.
Drugs or toxins are broken down (metabolized) so that they can be eliminated from the body. Grapefruit juice decreases the activity of the cytochrome P450 3A4 (CYP3A4) enzymes that are responsible for breaking down many drugs and toxins. Grapefruit contains compounds known as furanocoumarins that block the CYP3A4 enzymes. When grapefruit juice is consumed, the enzymeâs ability to break down the drug for elimination is decreased. Blood levels of the drug may rise, resulting in the risk for new or worsened side effects.
One or more substances in grapefruit and grapefruit juice block the action of an enzyme called cytochrome P-450 3A4 (CYP3A4). This enzyme breaks down a wide array of medications, including atorvastatin (Lipitor). (For an extensive list of drugs affected by grapefruit juice, visit health.harvard.edu/165.) Knocking CYP3A4 out of action means higher blood levels of these medications. One glass of grapefruit juice, or eating half a grapefruit, is enough to suppress CYP3A4 activity by half, and the effect lasts up to 24 hours.