Self-actualization, according to Maslow, represents the growth of an individual toward fulfillment of the highest needs. Maslow argues that only high acheivers are self-actualizers, but we are all in fact capable of self-actualization.
In a thrombotic stroke, a blood clot (thrombus) forms inside one of the brain's arteries. The clot blocks blood flow to a part of the brain. This causes brain cells in that area to stop functioning and die quickly.
HHMI researchers identify gene mutations that cause a potentially fatal clotting disorder. Researchers have determined the cause of a potentially deadly inherited blood-clotting disorder that can lead to kidney failure or stroke. The researchers found that the disorder, thrombotic thrombocytopenic purpura (TTP), is caused by mutations in a gene that render the ADAMTS13 enzyme ineffective.