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De Quervain's tenosynovitis is inflammation of tendons on the side of the wrist at the base of the thumb. These tendons include the extensor pollicis brevis and the abductor pollicis longus tendons, which extend the joints of the thumb. De Quervain's tenosynovitis can be brought on by simple strain injury to the extensor pollicis longus and abductor pollicis tendons (tendinitis). Often this form of tendinitis is a result of repetitive motion injury.
DeQuervain's disease is a swelling and inflammation of the tendon around the thumb, causing pain in the thumb and lower arm. Trauma or injury to any of the structures in the hand is another common cause of hand pain.