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A faulty valve. The main cause of acid reflux disease is a problem with the lower esophageal sphincter (LES) muscle. This muscle, which is the âvalveâ between the stomach and the esophagus, normally closes tightly after food has passed through to the stomach. The LES does not stay closed in people with acid reflux disease. When this happens, acid and stomach contents may back up (reflux) into the esophagus. This acid backup can sometimes cause the painful, burning sensation known as heartburn or other symptoms.
Stomach Ulcer. Left untreated, severe gastritis can lead to the formation of a hole in the stomach lining, which is also known as a peptic ulcer. After an ulcer has formed, the acidic liquids and foods can cause even greater pain than gastritis alone, an article in the June 1992 issue of the medical journal Gut reports.