In sickle cell disease, red blood cells are produced but then become deformed into the sickle shape, which causes red blood cells to lose their oxygen carrying capacity. The body subsequently becomes dehydrated, or with a fever.
some bipolar depression symptoms are the same as major depression symptoms persistent sadness feelings of hopelessness worthlessness and helplessness loss of interest in activities or hobbies once pleasurable including sex
Bipolar Symptoms: Depression. In bipolar disorder, manic episodes alternate with periods of emotional lows, which are known as depressive episodes. Signs of a depressive episode may include: 1  Sadness, anxiety, or a feeling of emptiness. 2  Hopelessness. 3  Feelings of guilt, feeling worthless, or feeling helpless.