Tweet. There are no known adverse reactions between Plavix (Clopidogrel) and eating grapefruit, or drinking grapefruit juice. Furthermore, there is no sufficient evidence that illustrates grapefruit juice, or the fruit itself would interfere with the effectiveness of Plavix.
Other, more minor side effects include constipation, headache, dry mouth and insomnia (because the chemicals in these drugs also influence sleep patterns). Herbal diet pills, even though they're all natural, can have potentially dangerous side effects depending upon their ingredients.
Most side effects of the pill are not serious. The most common such effects are nausea, vomiting, bleeding between menstrual periods, weight gain, breast tenderness, and difficulty wearing contact lenses. These side effects, especially nausea and vomiting, may subside within the first three months of use.