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Design of Experiments. Design of Experiments (DOE) is a study of the factors that the team has determined are the key process input variables (KPIV's) that are the source of the variation or have an influence on the mean of the output. A DOE (or set of DOE's) will help develop a prediction equation for the process in terms of Y = f(X1,X2,X3,X4,....Xn).
The dependent variable represents the output or effect, or is tested to see if it is the effect. The independent variable represents the input or cause, or is tested to see if it is the cause. Other variables may also be observed for various reasons.