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De Quervain's tenosynovitis is inflammation of tendons on the side of the wrist at the base of the thumb. These tendons include the extensor pollicis brevis and the abductor pollicis longus tendons, which extend the joints of the thumb. De Quervain's tenosynovitis can be brought on by simple strain injury to the extensor pollicis longus and abductor pollicis tendons (tendinitis). Often this form of tendinitis is a result of repetitive motion injury.
Constantly lifting children can also strain the tendons in the wrist and lead to this condition. If you have De Quervain tendinitis, you may notice: 1  Pain on the back of your thumb when you make a fist, grab something, or turn your wrist. 2  Numbness in the thumb and index finger.  Swelling of the wrist.