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Full Definition of DIPHTHERIA. : an acute febrile contagious disease typically marked by the formation of a false membrane especially in the throat and caused by a gram-positive bacterium (Corynebacterium diphtheriae) that produces a toxin causing inflammation of the heart and nervous system.
Diphtheria is an acute, toxin-mediated disease caused by the bacterium Corynebacterium diphtheriae. The name of the disease is derived from the Greek diphthera, meaning leather hide. The disease was described in the 5th century BCE by Hippocrates, and epidemics were described in the 6th century AD by Aetius.TaP (diphtheria and tetanus toxoids and acellular pertussis vaccine) is the vaccine of choice for children 6 weeks through 6 years of age. The usual schedule is a primary series of 4 doses at 2, 4, 6, and 15-18 months of age.