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Full Definition of DIPHTHERIA. : an acute febrile contagious disease typically marked by the formation of a false membrane especially in the throat and caused by a gram-positive bacterium (Corynebacterium diphtheriae) that produces a toxin causing inflammation of the heart and nervous system.
Diphtheria. Diphtheria is a serious bacterial disease that affects the respiratory system or the skin. diphtheria causes a sore throat and fever, and sometimes swelling of the neck. In severe cases it can cause a membrane to form over the throat, which results in breathing problems.iphtheria. Diphtheria is a serious bacterial disease that affects the respiratory system or the skin. diphtheria causes a sore throat and fever, and sometimes swelling of the neck. In severe cases it can cause a membrane to form over the throat, which results in breathing problems.