Also, be sure to see the Game of Thrones Characters chart, here. Below is a simpler chart focusing only on the four main families. It primarily shows the royal bloodline with all the claimants and possible claimants, including popular fan theories (SPOILERS!). Click it to enlarge.
Other drugs, known as prodrugs, are activated by the action of CYP2D6. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver.
Tamoxifen is a drug that is given to women who have estrogen-sensitive breast cancer. What does this tell you about the relationship between tamoxifen and the tumor cells in this case? The tumor cells must have receptors for estrogen, and tamoxifen is an agonist of estrogen receptors. The tumor cells have receptors for tamoxifen only.