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De Quervain's tenosynovitis is inflammation of tendons on the side of the wrist at the base of the thumb. These tendons include the extensor pollicis brevis and the abductor pollicis longus tendons, which extend the joints of the thumb. De Quervain's tenosynovitis can be brought on by simple strain injury to the extensor pollicis longus and abductor pollicis tendons (tendinitis). Often this form of tendinitis is a result of repetitive motion injury.
Signs of De Quervain's tendinosis: 1  Pain may be felt over the thumb side of the wrist. 2  Swelling may be seen over the thumb side of the wrist. 3  A catching or snapping sensation may be felt when moving the thumb.  Pain and swelling may make it difficult to move the thumb and wrist.