Thienopyridines, a class of oral antiplatelet agents, permanently inhibit P2RY12 signaling, which is sufficient to block platelet activation. F2R, TBXA2R and P2RY1 couple to the Gq-PLC-IP3-Ca2+ pathway, inducing shape change and platelet aggregation.
On April 1, 2001, the Austrian Regulatory Authority for Broadcasting and Telecommunications (RTR) was established under Austrian law.
DEFINITION of 'Internal Rate Of Return-IRR'. A metric used in capital budgeting measuring the profitability of potential investments. Internal rate of return is a discount rate that makes the net present value (NPV) of all cash flows from a particular project equal to zero.EFINITION of 'Internal Rate Of Return-IRR'. A metric used in capital budgeting measuring the profitability of potential investments. Internal rate of return is a discount rate that makes the net present value (NPV) of all cash flows from a particular project equal to zero.