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The DEPO will stay in your system for 3 months but you can become pregnant and conceive, before the 3 month time frame is up. One in a 100 women getting a Depo shot every 12 weeks will get pregnant in a year. After stopping it takes on average a further 9-10 months to get pregnant.he DEPO will stay in your system for 3 months but you can become pregnant and conceive, before the 3 month time frame is up. One in a 100 women getting a Depo shot every 12 weeks will get pregnant in a year. After stopping it takes on average a further 9-10 months to get pregnant.
Review this sheet carefully and report any questions or concerns to your health care provider. Return to the clinic every 11â13 weeks or 12â14 weeks (104 mg) for your shot. FPEM-6 Revised 7/11. Women who use Depo-Provera Contraceptive Injection (CI) may lose significant bone mineral density. Bone loss is greater with increasing duration of use and may not be completely reversible.