Thienopyridines, a class of oral antiplatelet agents, permanently inhibit P2RY12 signaling, which is sufficient to block platelet activation. F2R, TBXA2R and P2RY1 couple to the Gq-PLC-IP3-Ca2+ pathway, inducing shape change and platelet aggregation.
On April 1, 2001, the Austrian Regulatory Authority for Broadcasting and Telecommunications (RTR) was established under Austrian law.
Definition: The modified internal rate of return, or MIRR, is a financial formula used to measure the return of a project and compare it with other potential projects. It uses the traditional internal rate of return of a project and adapted to assume the difference between the reinvestment rate and the investment return. What Does the Modified Internal Rate of Return Mean? MIRR is a revised version of the internal rate of return (IRR), which calculates a reinvestment rate and accounts even or uneven cash flows.