Also, be sure to see the Game of Thrones Characters chart, here. Below is a simpler chart focusing only on the four main families. It primarily shows the royal bloodline with all the claimants and possible claimants, including popular fan theories (SPOILERS!). Click it to enlarge.
Other drugs, known as prodrugs, are activated by the action of CYP2D6. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver.
Tamoxifen is a drug used to treat breast cancer in both pre-menopausal women (women who have not yet gone through the menopause) and post-menopausal women (women who have gone through the menopause). It can also be taken by men who have breast cancer. It is a type of hormone treatment, also known as endocrine therapy.