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Psychologically disturbed children who bite and suck their fingers cause thickenings that resemble knuckle pads to occur in the skin in the traumatized areas. Patients with bulimia who use their knuckles or fingers to induce emesis sometimes develop fibrotic papules resembling knuckle pads. [8] Some cases of knuckle pads are familial.
By far the most common carpal tunnel syndrome cause is repetitive, forceful movements of the hand, especially with the wrist bent or the hand in an awkward position, that irritate the tendons and cause them to swell.