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Psychologically disturbed children who bite and suck their fingers cause thickenings that resemble knuckle pads to occur in the skin in the traumatized areas. Patients with bulimia who use their knuckles or fingers to induce emesis sometimes develop fibrotic papules resembling knuckle pads. [8] Some cases of knuckle pads are familial.
Vitamins E, B1, B6, B12 and niacin are essential for healthy nerve function. A lack of B12 can lead to pernicious anaemia, an important cause of peripheral neuropathy. However, too much B6 can also cause tingling in the hands and feet. Alcoholism. Alcoholics are more likely to have vitamin deficiencies because of poor dietary habits. Itâs also possible that alcoholism can cause nerve damage.