Also, be sure to see the Game of Thrones Characters chart, here. Below is a simpler chart focusing only on the four main families. It primarily shows the royal bloodline with all the claimants and possible claimants, including popular fan theories (SPOILERS!). Click it to enlarge.
Other drugs, known as prodrugs, are activated by the action of CYP2D6. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver.
By blocking the actions of estrogen in the breast tissue, tamoxifen helps slow the growth and reproduction of breast cancer cells. While taking tamoxifen may benefit many breast cancer patients (and women at high risk of the disease), tamoxifen has also been shown to cause bothersome side effects in some women.