MTHFR C677T Mutation Basics. The MTHFR C677T mutation affects the enzyme methylenetetrahydrofolate reductase, which is the rate-limiting enzyme in the formation of 5-methyltetraydrofolate (5-MTHF), or methylfolate.If you have the C677T mutation, your ability to convert folic acid into methylfolate is significantly reduced.olate found naturally in foods, such as leafy green vegetables, does not pose a problem.The MTHFR C677T mutation may also cause high homocysteine levels, as methylfolate plays an important role in homocysteine metabolism. Elevated homocysteine levels can cause oxidative stress and increase your risk of heart disease.
RPM: Always allow the disc sander to reach its full speed befoâ¦ Left: this is the down word side of the disc so your stock isâ¦ Table: this allows your stock to be supported and creates a 90â¦
Disc Sander. My primary sanding machine is a Makita GV5000 disc sander. Weighing in at just 2-1/2 pounds, this sander can be used for extended periods and at odd angles, works great for fascia boards, flat trim and wood siding. Be careful, this is a very powerful sander. If the sanding disk is to course or you stay in one place to long this sander could do some damage. I recommend practicing before using this disc sander on your home. Try sanding an old painted picket fence or a piece of trim that should be replaced anyway.