Postgraduate programs are getting a lot more practical with hands-on learning and job-focused training. By Christopher J. Gearon, Contributor | March 13, 2013, at 8:30 a.m. Focus on Job Skills With a Professional Master's Degree.
PARK2 (OMIM *602544) is the parkin gene that may cause a form of autosomal recessive juvenile Parkinson disease (OMIM 600116) due to a mutation in the parkin protein. This form of genetic mutation may be one of the most common known genetic causes of early-onset Parkinson disease.In one study of patients with onset of Parkinson disease prior to age 40 (10% of all PD patients), 18% had parkin mutations, with 5% homozygous mutations.his form of genetic mutation may be one of the most common known genetic causes of early-onset Parkinson disease. In one study of patients with onset of Parkinson disease prior to age 40 (10% of all PD patients), 18% had parkin mutations, with 5% homozygous mutations.
These genes are names for their recessive mutant phenotypes, so mice homozygous mutant at the albino locus have no pigmentation (white fur and pink eyes) and heterozygotes and wild type for albino have pigmentation (dark fur and eyes). The albino gene product, tyrosinase, is necessary for the synthesis of all pigment. Mice have two different pigments in each hair, yellow at the tip and black in the rest of the hair. In albino mutants, neither pigment is made. The nonagouti gene product is necessary for the production of the yellow pigment, so mutant nonagouti mice have black hair.