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Subcutaneous emphysema can be caused by medical procedures and medical conditions that cause the pressure in the alveoli of the lung to be higher than that in the tissues outside of them. Its most common causes are pneumothorax and a chest tube that has become occluded by a blood clot or fibrinous material.
The most common cause of emphysema is smoking. Pulmonary fibrosis involves scarring, or fibrosis, in the lungs. This process causes air sacs and the supporting lung tissue to become stiff and thick. Fibrosis worsens over time and the lungs are not able to move oxygen into the blood stream.