The Battle of Normandy was fought during World War II in the summer of 1944, between the Allied nations and German forces occupying Western Europe.
serum tsh is usually regarded as a marker of thyroid function on the basis of a simple feedback model tsh is released from the anterior pituitary gland in response to thyroid releasing hormone from the hypothalamus and causes the synthesis and secretion of thyroxine t4 and triiodothyronine t3 by the thyroid gland
When maternal TSH is elevated, measurement of serum FT4 concentration is necessary to classify the patient's status as either subclinical (SCH) or overt hypothyroidism (OH). SCH is defined as a serum TSH between 2.5 and 10 mIU/L with a normal FT4 concentration. Women with a TSH concentration above the trimester-specific reference interval with a decreased FT4, and all women with a TSH concentration above 10.0 mIU/L irrespective of the level of FT4 are also considered to have OH. [3]