(Redirected from Opportunistic infections) An opportunistic infection is an infection caused by pathogens (bacteria, viruses, fungi, or protozoa) that take advantage of an opportunity not normally available, such as a host with a weakened immune system, an altered microbiota (such as a disrupted gut flora), or breached integumentary barriers.
If someone is described as being 'rough around the edges' it means they are generally good but have a few faults on the outside. Rough around the edges has many meanings: Worn out; Not polished or refined; Not great but not bad either; ans Unkempt.
Burning Pain on Outside Edge of Foot. Burning foot pain may be the result of poor footwear Photo Credit Feet image by Tomasz Pawlowski from Fotolia.com. Burning pain on the outside edge of the foot can be caused by improper footwear, infection or a serious medical condition. Diabetes, peripheral neuropathy and obesity are all factors that can affect the foot, causing pain and burning sensations.