Deep vein thrombosis â Perhaps the most important disease not to miss when dealing with legs that have suddenly become swollen. Years after the deep vein thrombosis has subsided and forgotten, post-phlebitic changes can still be a cause for a swollen leg.
1 A patent foramen ovale (PFO) is an opening covered by a flap of tissue in the wall of the heart that separates the two upper chambers or atria. 2  PFOs are very common, more than 20% of all humans have one.3  Estimates range from 20-30% depending on the decade of life. A patent foramen ovale (PFO) is an opening covered by a flap of tissue in the wall of the heart that separates the two upper chambers or atria. 2  PFOs are very common, more than 20% of all humans have one. 3  Estimates range from 20-30% depending on the decade of life.
A patent foramen ovale (PFO) is a defect in the septum (wall) between the two upper (atrial) chambers of the heart. Specifically, the defect is an incomplete closure of the at â¦ rial septum that results in the creation of a flap or a valve-like opening in the atrial septal wall (see illustration).