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Usually, receptors are proteins found on or within the membrane. Many different types of molecules can bind to receptors on the cell surface, including hormones. An insulin receptor is an example of a receptor that binds to a hormones, specifically insulin.
A G-protein-linked receptor activates G protein, which activates phospholipase C, which cleaves a membrane lipid to form IP3, which binds to a calcium channel on the ER, which opens to release calcium ions into the cytoplasm, which bind to an intracellular enzyme that carries out a response.