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Pizza Hut, Thin Crust Pepperoni, Large, 1 Slice (1 serving) Calories: 300, Fat: 14g, Carbs: 29g, Protein: 14g.
Report Abuse. The calories in a slice of pizza varies depending on the size of the slice, the thickness of the crust, and the toppings. For example, -- One serving (one slice) of Pizza Hut cheese pizza with a thin crust has 225 calories. Based on one-eighth of a 14-inch pizza. -- One serving (two slices) of Pizza Hut Supreme with pan-style crust has 622 calories.