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Subcutaneous emphysema can be caused by medical procedures and medical conditions that cause the pressure in the alveoli of the lung to be higher than that in the tissues outside of them. Its most common causes are pneumothorax and a chest tube that has become occluded by a blood clot or fibrinous material.
Cigarette smoke also causes inflammation and irritation in the lungs leading to an increase in mucus production. Too much mucus in the lungs places you at an increased risk for lung infections, as mucus provides bacteria with the perfect hide-away. Air pollution also plays a role in the development of emphysema.