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Simply put, Colitis is swelling (inflammation) of the large intestine (colon). In medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).n medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).
Ulcerative colitis is an inflammatory bowel disease of unknown cause in which the gastrointestinal tract is unable to distinguish foreign from self-antigens. It is characterized by chronic inflammation of the colonic mucosa and submucosa, atrophy and possibly dysplasia limited to the colon.