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Simply put, Colitis is swelling (inflammation) of the large intestine (colon). In medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).n medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).
Ulcerative colitis is an inflammatory bowel disease (IBD) of unknown cause. It is characterized by chronic inflammation and ulceration of the lining of the major portion of the large intestine (colon). In most affected individuals, the lowest region of the large intestine, known as the rectum, is initially affected.