100 acres Holy Cross, IA 100 acres of prime hunting ground in Dubuque County. Native grasses, wildflowers, and food plots create an oasis for whitetail, turkey, and pheasants to thrive.
There are many combinations of MTHFR: 1  Homozygous: means you have both copies of either the 677 mutation, or the 1298 mutation, one from from each parent. 2  Heterozygous: means you have one copy of either the 677 mutation, or the 1298 mutation, plus a normal one from the other parent.ore than one mutation of the MTHFR gene. Genes are passed down by your mother and your father. Most literature states there are a good 40-50 different mutations of this important gene which could be passed down by one, or both or your parents.
Furthermore, a MTHFR C677T mutation may cause elevated levels of homocysteine in the body. Homocysteine contributes to oxidative stress and increases risk of heart disease when elevated. MTHFR A1298C MTHFR A1298C mutations affect conversion of methylfolate into BH4, or tetrahydrobiopterin.THFR A1298C mutations may also affect melatonin production, which often leads to sleep disturbances. Additionally, BH4 is important for heart health and deficiency may play a role in the development of cardiovascular disease. MTHFR Treatment The treatment of MTHFR mutations is often a two-pronged approach.