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Simply put, Colitis is swelling (inflammation) of the large intestine (colon). In medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).n medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).
Difference Between Colitis and Ulcerative Colitis. Definition. Colitis is a general term used to describe the inflammation of the lining of colon. Ulcerative colitis is one form of colitis, which results in the chronic inflammation of colonic mucosa and rectum giving rise to ulceration and bleeding.