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Aldosterone, like ADH also acts on the distant tubules, but also at the kidneyâs collecting ducts. Water retention with the aid of aldosterone is more complex because it has to undergo the Sodium-Potassium exchange channels. In this set-up, potassium is excreted while sodium is retained.
Some sources say angiotensin II stimulates production of all of the enzymes used in the synthesis of aldosterone, others say it just acts on the first and last enzymes, and still others say it just on the last enzyme (aldosterone synthase). Same goes for ACTH.