A slight chance of showers between 9pm and 3am, then a chance of showers and thunderstorms after 3am. Some of the storms could produce heavy rain. Cloudy, with a low around 58. East wind around 8 mph. Chance of precipitation is 50%.
As per ACCF/AHA guidelines, a loading dose to initiate digoxin therapy in patients with heart failure is not necessary. 0.125-0.25 mg PO/IV qDay; higher doses including 0.375-0.5 mg/day rarely needed. Use lower end of dosing (0.125 mg/day) in patients with impaired renal function or low lean body mass.
Digoxin Metabolism in the Elderly By GOBDON A. Ewy, M.D., GEETA G. K.APADiA, PH.D., LINDA YAO,MURIEL LULLIN, AND FRANx I. MARCUS, M.D.SUMMARYTritiated digoxin (0.5 mg) was given intravenously to five elderly men (mean age,77years) andnineyoung men (meanage, 27years). Theelderly were not in congestiveheart failure.