1 Non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke, either of which can lead to death. 2  There are a large number of studies that support this finding, with varying estimates of how much the risk is increased, depending on the drugs and the doses studied.
Symptoms of thalassemia may include one or more of the following: 1  Paleness. 2  Tiredness, low energy, or muscle weakness (also called fatigue) 3  Lightheadedness or shortness of breath.  Lack of 1  appetite. Dark urine.  Jaundice (yellowing of the skin and the whites of the 1  eyes) In children, slow growth and delayed puberty.  Bone deformities in the face.
The most common symptom of all types of anemia is fatigue (tiredness). Fatigue occurs because your body doesn't have enough red blood cells to carry oxygen to its many parts. Also, the red blood cells your body makes have less hemoglobin than normal.Hemoglobin is an iron-rich protein in red blood cells.nemia also can cause shortness of breath, dizziness, headache, coldness in your hands and feet, pale skin, chest pain, weakness, and fatigue (tiredness). If you don't have enough hemoglobin-carrying red blood cells, your heart has to work harder to move oxygen-rich blood through your body.