Actor. Daniel Zovatto; Stephen Lang; Jane Levy; Maika Monroe; Keir Gilchrist; Olivia Luccardi; Jake Weary; Lili Sepe + See more; John Weary; Mark Margolis; Dylan Minnette; Griffin Newman; Bonnie Dennison; Danny Zovatto; Mackenzie Rosman-See Less; Director. Fede Alvarez; David Robert Mitchell; Larry Fessenden; Craig Zisk; Michael Uppendahl; TV Networks & Studios. AMC; Avg. Customer Review
The 5-HT1B receptor as an example of a metabotropic serotonin receptor. The serotonin receptors, also known as 5-hydroxytryptamine receptors or 5-HT receptors, are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.
The human serotonin transporter (SERT) and norepinephrine transporter (NET) are membrane proteins that are responsible for the reuptake of serotonin and norepinephrine. Balanced dual inhibition of monoamine reuptake can possibly offer advantages over other antidepressants drugs by treating a wider range of symptoms. SNRIs, along with selective serotonin reuptake inhibitors (SSRIs) and norepinephrine reuptake inhibitors (NRIs), are second-generation antidepressants.