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GERD or acid reflux symptoms are caused by the regurgitation of acidic liquid stomach contents back up into the esophagus. The most common symptom of GERD is heartburn. Other symptoms that can occur as a result of GERD include: nausea,
In general, certain medications contribute to GERD by: 1  Weakening the esophageal sphincter. 2  Some medicine makes acid reflux more likely by weakening the lower esophageal sphincter (LES), the valve that connects the esophagus and the stomach.3  This allows acid to backflow into the esophagus. Other medications worsen GERD symptoms by exacerbating existing inflammation in the esophagus that has been caused by acid reflux. 2  Slowing digestion. 3  Some medications slow down the body's digestive system, allowing food to collect in the stomach and causing an increase in gastric acid production.