(Redirected from Opportunistic infections) An opportunistic infection is an infection caused by pathogens (bacteria, viruses, fungi, or protozoa) that take advantage of an opportunity not normally available, such as a host with a weakened immune system, an altered microbiota (such as a disrupted gut flora), or breached integumentary barriers.
If someone is described as being 'rough around the edges' it means they are generally good but have a few faults on the outside. Rough around the edges has many meanings: Worn out; Not polished or refined; Not great but not bad either; ans Unkempt.
What Goes Around.../...Comes Around is about betrayal and forgiveness. Timberlake revealed that the song was written for the experience his friend went through. However, the public came up with different interpretation of the lyrics, that being a sequel to  Cry Me A River .