1 Non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke, either of which can lead to death. 2  There are a large number of studies that support this finding, with varying estimates of how much the risk is increased, depending on the drugs and the doses studied.
Symptoms of thalassemia may include one or more of the following: 1  Paleness. 2  Tiredness, low energy, or muscle weakness (also called fatigue) 3  Lightheadedness or shortness of breath.  Lack of 1  appetite. Dark urine.  Jaundice (yellowing of the skin and the whites of the 1  eyes) In children, slow growth and delayed puberty.  Bone deformities in the face.
Iron deficiency anemia can cause you to fatigue earlier during exercise and make you feel more short of breath. You may have nausea, be more irritable and feel generally run down. Visibly, you may appear pale and washed out.