Pan-African flag - History. 1  The flag was created in 1920 by members of UNIA in response to the enormously popular 1900 coon song Every Race Has a Flag but the Coon. [4] which has been cited as one of the three songs that firmly established the term coon in the American vocabulary.
A ligand is any molecule that binds to a specific site on a protein or other molecule. In this case, the estrogen hormone 17-beta-estradiol is the ligand, and the estrogen receptor is the protein. Binding turns on, or activates, a hormone receptor.
A signaling molecule. The term ligand is used for a molecule that specifically binds to another molecule, often a larger one. Ligand binding generally causes a receptor protein to undergo a change in shape.For many receptors, this shape change directly activates the receptor, enabling it to interact with other cellular molecules.For other kinds of receptors, the immediate effect of a ligand binding is to cause the aggregation of two or more receptor molecules, which leads to further molecular events inside the cell.or many receptors, this shape change directly activates the receptor, enabling it to interact with other cellular molecules. For other kinds of receptors, the immediate effect of a ligand binding is to cause the aggregation of two or more receptor molecules, which leads to further molecular events inside the cell.