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Hypothyroidism (underactive thyroid) Overview. Hypothyroidism (underactive thyroid) is a condition in which your thyroid gland doesn't produce enough of certain important hormones. Women, especially those older than age 60, are more likely to have hypothyroidism. Hypothyroidism upsets the normal balance of chemical reactions in your body.
It's a small, butterfly-shaped gland that sits in your neck. It makes a hormone that helps control how you use energy. When your thyroid gland is out of whack, you're out of whack. People with an underactive thyroid are going to feel tired, Friedman says.