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Vitamin B 12 (cobalamin) deficiency is a common cause of macrocytic anemia and has been implicated in a spectrum of neuropsychiatric disorders.The role of B 12 deficiency in hyperhomocysteinemia and the promotion of atherosclerosis is only now being explored.itamin B 12 deficiency, therefore, can lead to increased levels of serum methylmalonic acid. In the second reaction, homocysteine is converted to methionine by using vitamin B 12 and folic acid as cofactors. In this reaction, a deficiency of vitamin B 12 or folic acid may lead to increased homocysteine levels.
Vitamin B12 (Cyanocobalamin) deficiency causes white spots on the skin. Vitamin B12 is a water soluble vitamin of the B complex and one of its form is known as Cyanocobalamin. Vit B12 is vital for the normal functioning of the nervous system and in the production of other B complex vitamins.itamin B12 deficiency causes white spots on the skin. These vit B12 deficiency white spots on skin, lack melanin and occur anywhere on the body. These vit B12 deficiency caused white spots may be itchy, often occurring on the outside of the forearm.