A slight chance of showers between 9pm and 3am, then a chance of showers and thunderstorms after 3am. Some of the storms could produce heavy rain. Cloudy, with a low around 58. East wind around 8 mph. Chance of precipitation is 50%.
As per ACCF/AHA guidelines, a loading dose to initiate digoxin therapy in patients with heart failure is not necessary. 0.125-0.25 mg PO/IV qDay; higher doses including 0.375-0.5 mg/day rarely needed. Use lower end of dosing (0.125 mg/day) in patients with impaired renal function or low lean body mass.
Therapeutic serum digoxin levels range from 0.5â2 ng/mL. Serum levels may be drawn 6â8 hr after a dose is administered, although they are usually drawn immediately before the next dose. Bacteria in the GI tract can metabolize a substantial amount of digoxin before it is absorbed.