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It's true that protein can help you stay satisfied longer and help you build muscle that will boost your body's calorie-burning potential. Even so, eating too much of any kind of foodâincluding proteinâwill eventually lead to weight gain. Plus, going too heavy on the stuff can have more serious health consequences. Too much protein might mess with your body's ability to metabolize glucose, and can also cause problems with kidney function, says study coauthor MÃ²nica BullÃ³, PhD.
But trans fats also slow down your body's ability to burn fat. They have an altered shape and make your biochemistry run funny, Hyman says, explaining that trans fat binds to fat and liver cells and slows metabolism. Eating trans fat can also lead to insulin resistance and inflammation, both of which cripple metabolism and can cause weight gain.