It felt wintry cold that day. 5 verb If you feel an object, you touch it deliberately with your hand, so that you learn what it is like, for example what shape it is or whether it is rough or smooth. The doctor felt his head... When dry, feel the surface and it will no longer be smooth...
We studied daratumumab, a CD38-targeting, human IgG1Îº monoclonal antibody, in a phase 1â2 trial involving patients with relapsed myeloma or relapsed myeloma that was refractory to two or more prior lines of therapy.e studied daratumumab, a CD38-targeting, human IgG1Îº monoclonal antibody, in a phase 1â2 trial involving patients with relapsed myeloma or relapsed myeloma that was refractory to two or more prior lines of therapy.
âThe current median PFS in the 16-mg/kg group is 23 weeks, which is also the longest follow-up of any patient in this cohort,â Lokhorst said. The median PFS in the 8-mg/kg group was 14.9 months. Several phase III studies are exploring daratumumab as a treatment for patients with relapsed or refractory multiple myeloma. One study is exploring the drug with lenalidomide and dexamethasone compared with lenalidomide and dexamethasone alone. This study is currently recruiting patients.