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Subcutaneous emphysema can be caused by medical procedures and medical conditions that cause the pressure in the alveoli of the lung to be higher than that in the tissues outside of them. Its most common causes are pneumothorax and a chest tube that has become occluded by a blood clot or fibrinous material.
Some possible causes of blood streaked sputum include: 1  Inflammation and irritation of the airways from repeated coughing. 2  Bronchitis. 3  Bronchiectasis. Lung cancer. 4  Pneumonia. Pulmonary edema.  Blood clots in the lungs (pulmonary embolus) - With pulmonary emboli, people often have pain, redness or swelling in their calves due to deep vein thrombosis.