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From the WebMD Archives. May 25, 2011 -- Just in time for the start of grilling season, the U.S. Department of Agriculture has updated guidelines for safely preparing pork. The USDA recommends that pork be cooked to an internal temperature of 145 degrees Fahrenheit.
It's about 20 minutes per pound at 350 degrees, but it's more important to test the doneness with an instant read thermometer. The pork is done when the temperature measured at the thickest part of the meat (away from the bone) is 145-150 degrees. I would reduce the heat to 325Â° and bake 22 min.