A slight chance of showers between 9pm and 3am, then a chance of showers and thunderstorms after 3am. Some of the storms could produce heavy rain. Cloudy, with a low around 58. East wind around 8 mph. Chance of precipitation is 50%.
As per ACCF/AHA guidelines, a loading dose to initiate digoxin therapy in patients with heart failure is not necessary. 0.125-0.25 mg PO/IV qDay; higher doses including 0.375-0.5 mg/day rarely needed. Use lower end of dosing (0.125 mg/day) in patients with impaired renal function or low lean body mass.
The incidence of digoxin toxicity increases with age, largely because the two most common conditions that benefit from use of digoxin, congestive heart failure and atrial fibrillation, are markedly more prevalent in old age.hether the elderly are more sensitive to the effects of digoxin because of age per se is unclear. However, several other factors render the elderly more susceptible to digoxin toxicity. These include an age-related decline in renal function and a decrease in volume of digoxin distribution.