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A slough is a swamp or shallow lake system, usually a backwater to a larger body of water. The Elkhorn Slough NERR is a narrow meandering inlet located off Monterey Bay on California's central coast (Image credit: Elkhorn Slough NERR).A slough (pronounced slew) is typically used to describe wetlands.Sloughs along the edges of rivers form where the old channel of the river once flowed.hile this term is used differently across the country, on the West Coast a slough is referred to as a swamp or shallow lake system, usually a backwater to a larger body of water.
1 v, to shed or cast off dead tissue, such as cells of the endometrium, shed during menstruation. 2 n, the tissue that has been shed. slough. noun A deprecating term for a patient that a doctor, ward or hospital tries to pass off on another doctor, ward or hospital without appropriate indications. noun Dead skin or tissue that has fallen off of decubital ulcers or other parts of the patientâs body.