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The most common skin disorders that a vitamin D allergy can cause include hives and eczema, according to Drugs.com. Both allergic skin conditions are extremely itchy and cause inflammation and irritation in the skin. Hives may indicate a severe allergic reaction and needs to be evaluated by a physician.
Vitamin D response element (VDRE) is a DNA sequence that is found in the promoter region of vitamin D regulated genes. The receptor for 1,25(OH)2D (VDR) binds to and regulates the expression of some genes. These response elements typically consist of two conserved hexameric half-sites separated by a three nucleotide spacer, referred to as a DR3 type element.