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The mean reticulocyte hemoglobin content (CHr) and reticulocyte hemoglobin equivalent (Ret-He) are two equivalent parameters that capture the amount of hemoglobin available to the reticulocytes within the previous 3-4 days. Both parameters directly correlate with the functional availability of iron in the bone marrow.he automated hematology analyzer can also report a measurement of reticulocyte-specific hemoglobin content as mean reticulocyte hemoglobin content (CHr) or reticulocyte hemoglobin equivalent (Ret-He), depending on the type of instrument used.
The normal fraction of reticulocytes in the blood depends on the clinical situation but is usually 0.5% to 2.5% in adults and 2% to 6% in infants. A reticulocyte percentage that is higher than normal can be a sign of anemia, but this depends on the health of a person's bone marrow. Calculating the reticulocyte production index is an important step in understanding whether or not the reticulocyte count is appropriate to the situation.