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Vitamin B 12 (cobalamin) deficiency is a common cause of macrocytic anemia and has been implicated in a spectrum of neuropsychiatric disorders.The role of B 12 deficiency in hyperhomocysteinemia and the promotion of atherosclerosis is only now being explored.itamin B 12 deficiency, therefore, can lead to increased levels of serum methylmalonic acid. In the second reaction, homocysteine is converted to methionine by using vitamin B 12 and folic acid as cofactors. In this reaction, a deficiency of vitamin B 12 or folic acid may lead to increased homocysteine levels.
Vitamin B12 is a water-soluble vitamin that keeps your nerves and red blood cells healthy. It is responsible for the smooth functioning of several critical body processes. It is possible for the body to develop a vitamin B12 deficiency.This deficiency is usually reported... health, benefits, of, vitamin, b12, benefits, of, vitamin, b12, vitamin, b12, benefits, b12, supplement, and, health, benefits, vitamin, b, 12, health, benefits.t is possible for the body to develop a vitamin B12 deficiency. This deficiency is usually reported with symptoms of fatigue. Strict vegetarians, heavy drinkers and smokers, pregnant and breast-feeding women, and the elderly usually require vitamin B12 supplements.