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Simply put, Colitis is swelling (inflammation) of the large intestine (colon). In medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).n medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).
Microscopic Colitis. Microscopic colitis, which includes collagenous colitis and lymphocytic colitis, is characterized by chronic diarrhea caused by inflammation in the colon. It is not related to ulcerative colitis or to Crohn's disease, which are more severe forms of inflammatory bowel disease.