Bipolar disorder patients die prematurely from a wide range of causes, from heart disease to the flu, a Swedish population study showed. But that grim trend might be eased by increased access to primary care providers, Casey Crump, MD, PhD, of Stanford University in Stanford, Calif., and colleagues reported online in JAMA Psychiatry.
LCMV is a viral infection in mice, but it can also be carried by other rodents such as. hamsters, gerbils and guinea pigs. Infected rodents can pass the disease to humans.
We used persistent murine CMV (MCMV) infection to dissect the impact of CD4 + T cells on virus-specific CD8 + T cells, distinguishing between increased viral load in the absence of CD4 + T cells and CD4 + T-cell-mediated helper mechanisms.requencies of M45- and M38-specific CD8 + T cells were not reduced in MCMV-infected IL-21R â/â in comparison with WT mice (Fig. 4A), making it unlikely that CD4 + T cells support CD8 + T-cell responses by IL-21 during MCMV infection, unlike in murine LCMV or human HIV-1 infection.