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The most common skin disorders that a vitamin D allergy can cause include hives and eczema, according to Drugs.com. Both allergic skin conditions are extremely itchy and cause inflammation and irritation in the skin. Hives may indicate a severe allergic reaction and needs to be evaluated by a physician.
Taking a vitamin D-3 supplement has the potential to trigger an allergic reaction in some people. This occurs when your body mistakenly recognizes the vitamin D-3 as a potentially harmful chemical and mounts an immune response against it.