(carbamazepine) Extended-release Tablets 100 mg, 200 mg, 400 mg. WARNING. SERIOUS DERMATOLOGIC REACTIONS AND HLA-B*1502 ALLELE. SERIOUS AND SOMETIMES FATAL DERMATOLOGIC REACTIONS, INCLUDING TOXIC EPIDERMAL NECROLYSIS (TEN) AND STEVENS-JOHNSON SYNDROME (SJS), HAVE BEEN REPORTED DURING TREATMENT WITH TEGRETOL.
Von Willebrand disease (VWD) is a bleeding disorder. It affects your blood's ability to clot. If your blood doesn't clot, you can have heavy, hard-to-stop bleeding after an injury. The bleeding can damage your internal organs. Rarely, the bleeding may even cause death. In VWD, you either have low levels of a certain protein in your blood or the protein doesn't work well. The protein is called von Willebrand factor, and it helps your blood clot. Normally, when one of your blood vessels is injured, you start to bleed. Small blood cell fragments called platelets (PLATE-lets) clump together to plug the hole in the blood vessel and stop the bleeding.
hemophilia is an inherited bleeding disorder in which the blood does not clot properly this can lead to spontaneous bleeding as well as bleeding following injuries or surgery blood contains many proteins called clotting factors that can help to stop bleeding