1 Non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke, either of which can lead to death. 2  There are a large number of studies that support this finding, with varying estimates of how much the risk is increased, depending on the drugs and the doses studied.
Symptoms of thalassemia may include one or more of the following: 1  Paleness. 2  Tiredness, low energy, or muscle weakness (also called fatigue) 3  Lightheadedness or shortness of breath.  Lack of 1  appetite. Dark urine.  Jaundice (yellowing of the skin and the whites of the 1  eyes) In children, slow growth and delayed puberty.  Bone deformities in the face.
Anemia can happen when your body isnât producing enough red blood cells or the red blood cells donât contain enough iron-rich hemoglobin, says Amy L. Doneen, ARNP, medical director of the Heart Attack & Stroke Prevention Center. That lack of oxygen-rich blood in your body can make you feel tired and weak. While iron deficiency is the most common cause of anemia, other causes include heavy periods, sluggish bone marrow, vitamin B12 deficiency or a lack of folate in the diet, says Dr. Rindfleisch.