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After getting the Tdap vaccine as a preteen or teen, adults need to get a Td (tetanus and diphtheria) booster shot every 10 years to stay protected. For adults who didn't get Tdap as a preteen or teen, the easiest thing to do is to get Tdap instead of their next regular Td booster.
The recommended dose of the tetanus booster is a 0.5 mL injection every 10 years. Immunosuppressive drugs like corticosteroids, antimetabolites, alkylating agents, cytotoxic drugs and radiation may interact with the tetanus booster. Tell your doctor all medications you use. Exercise caution if you get the tetanus booster and have had Guillain-Barre syndrome, have thrombocytopenia, or are prone to blood clots. If you are pregnant and have not received the tetanus booster it is recommended to receive the vaccine after the second trimester.