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Mole is the generic name for a number of sauces originally used in Mexican cuisine, as well as for dishes based on these sauces. Outside Mexico, it often refers specifically to mole poblano. In contemporary Mexico, the term is used for a number of sauces, some quite dissimilar, including black, red/colorado, yellow, green, almendrado, de olla, huaxmole and pipiÃ¡n. Generally, a mole sauce contains a fruit, chili pepper, nut and such spices as black pepper, cinnamon, cumin, and chocolate.
Medical Definition of mole. : the base unit in the International System of Units for the amount of pure substance that contains the same number of elementary entities as there are atoms in exactly 12 grams of the isotope carbon 12 a mole of photons a mole of sodium chloride.