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Vitamin B 12 (cobalamin) deficiency is a common cause of macrocytic anemia and has been implicated in a spectrum of neuropsychiatric disorders.The role of B 12 deficiency in hyperhomocysteinemia and the promotion of atherosclerosis is only now being explored.itamin B 12 deficiency, therefore, can lead to increased levels of serum methylmalonic acid. In the second reaction, homocysteine is converted to methionine by using vitamin B 12 and folic acid as cofactors. In this reaction, a deficiency of vitamin B 12 or folic acid may lead to increased homocysteine levels.
10 Benefits of Vitamin B12. We all know that each vitamin (A, B, C, etc) all have different versions of themselves, but do many of us really know what their differences are? Itâs pretty uncommon knowledge, for instance, that the most common vitamin B you consume is actually vitamin B12 and itâs one of the most important, too. Vegetarians and vegans in particular miss out when they donât consume vitamin B12 which is a product of only meat, eggs, and fish. No plant food in the world contains this vitamin and if you want to know exactly what you might be missing out on, read on for the top 10 benefits of vitamin B12.