(Redirected from Opportunistic infections) An opportunistic infection is an infection caused by pathogens (bacteria, viruses, fungi, or protozoa) that take advantage of an opportunity not normally available, such as a host with a weakened immune system, an altered microbiota (such as a disrupted gut flora), or breached integumentary barriers.
If someone is described as being 'rough around the edges' it means they are generally good but have a few faults on the outside. Rough around the edges has many meanings: Worn out; Not polished or refined; Not great but not bad either; ans Unkempt.
If you have ever had a hangnail, you probably know what a paronychia feels like. Paronychia is an infection around the fingernail in one of the folds around the nail. The skin fold swells and becomes tender or reddened. Sometimes a pocket of pus accumulates which creates more pressure against the edge of the nail and it becomes increasingly tender and sensitive to touch. Even a band-aid can be painful to apply.