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Pizza Hut, Thin Crust Pepperoni, Large, 1 Slice (1 serving) Calories: 300, Fat: 14g, Carbs: 29g, Protein: 14g.
How Many Calories in a Slice of Pizza. Depends on the ingredients used to make the pizza. A simple Cheese and Pepperoni Pizza can cost an average of 250-350 calories per small slice. This is mainly due to the pizza dough, cheese and seasoning as well as the processed meat slices.