Malignancy rate of ground-glass nodules at baseline CT. Compared to a malignancy rate of 4.6% for all solid nodules, nodular GGO (nGGO) had a higher malignancy rate of 5.4%, pure nodular GGO (pnGGO) had a malignancy rate of 3.3%, and mixed nodular GGO (mnGGO) had a malignancy rate of 14.3%.
In the most common form of tetanus, the first sign is spasm of the jaw muscles, followed by stiffness of the neck, difficulty in swallowing, and stiffness of the abdominal muscles.Other signs include fever, sweating, elevated blood pressure, and rapid heart rate.
These signs and symptoms of clinical tetanus occur when inhibitory neurons in the spinal cord and brain stem are affected. The spastic paralysis seen in tetanus is the result of excessive acetylcholine release caused by the disinhibition of motor neurons (Cook 2001).