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Thatâs likely the concern among women who use popular osteoporosis drugs like alendronate (Fosamax and generic), ibandronate (Boniva), risedronate (Actonel) and zoledronic acid (Reclast) after it was reported this week by ABC News that these drugs could be associated with a risk of thigh bone (femur) fractures.
âTaking Boniva makes your bones more prone to fracture, and hereâs why this happens. Exactly like its main competitors, Fosamax, Actonel, and Reclast, Boniva works against natural bone metabolism. You see, Boniva binds to the bone matrix and stops normal bone resorption by inhibiting bone cells known as osteoclasts.