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All patients with stable angina should be treated with aspirin and a statin, unless contraindicated.1 ACE inhibitors are recommended for patients with co-existing conditions that would benefit from this treatment (Table 2). Table 2: Medicines to improve prognosis for stable angina (adapted from Abrams, 2005)2.
Statin users with either stable angina or non-ST-elevation acute coronary syndrome were randomized to a re-load dose of 80 mg of atorvastatin 12 hours before PCI plus an additional 40-mg dose on the way to the cath lab (177 patients). Placebo was administered to 175 patients on the same schedule.n the first study, compared with placebo, an 80-mg dose of atorvastatin delivered 24 hours before PCI reduced the rate of periprocedural myocardial infarction by 44% in statin-naive patients (P.