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Benadryl Dosage for Dogs: It is administered by giving 1 milligram for every pound of a dogâs weight after every 8 hours or three times per day. A good example would be, a dog weighing 40lb should take 40mg of Benadryl three times within a single day.
The usual dose of Benadryl for dogs (adult) is 2 to 4 milligrams per kilogram of body weight, which corresponds to a dose of 0.9 to 1.8 miligrams per pound of body weight, according to the Merck Veterinary Manual.