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Simply put, Colitis is swelling (inflammation) of the large intestine (colon). In medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).n medicine, colitis refers to an inflammation of the colon and is often used to describe an inflammation of the large intestine (colon, caecum and rectum).
Colitis Topic Guide. Colitis (Symptoms, Types, and Treatments): Colitis is an inflammation of the colon. There are many cause of colitis, infectious colitis (bacterial or viral), ischemic colitis, inflammatory bowel disease (Crohn's disease, ulcerative colitis), microscopic colitis (lymphocytic and collagenous), and chemical colitis.