All substances take up the least amount of volume in their (1.) solid phase, a little more volume in their (2.) liquid phase, and the largest amount of volume in their (3.) gas phase. The closer atoms or molecules get to one another, the less volume is occupied by the substance that they comprise.
A large, retrospective series examining human bite wounds in children found that none of the bites manifesting as abrasions became infected, while the rate of infection was much higher in bite wounds that caused punctures or lacerations.
One of few common spiders whose bites can have a seriously harmful effect on humans, the brown recluse has venom that contains a rare protein that can cause a blackened lesion at the site of a bite, or a much less common, but more dangerous, systemic reaction in humans.