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Otitis media with effusion (OME) and ear infections are connected in two ways: 1  After most ear infections have been treated, fluid (an effusion) remains in the middle ear for a few days or weeks.  When the Eustachian tube is partially blocked, fluid builds up in the middle ear.
In some cases, otitis media can be more chronic (with fluid in the middle ear for 6 weeks or longer) or, in otitis media with effusion, fluid in the middle ear can be temporary and not necessarily infected. Doctors try to distinguish between the different forms of otitis because this affects treatment options.