(IS, 4S)-4-(3, 4-dichlorophenyl)-l, .2, 3, 4- tetrahydro-N-metihyl-1-naphthalenamine, commonly known as Sertraline, is marketed in the form of its hydrochloride salt. Sertraline is used in the treatment of depression, obsessive-compulsive disorder and panic disorder.UMMARY OF THE INVENTION. The present invention discloses a novel method for the preparation of racemic sertraline starting from the known tetralone and cis(+) sertraline hydrochloride form II from cis(+) sertraline mandelate.
The mitral valve (also known as the bicuspid valve or left atrioventricular valve) is a dual-flap (bi-from the Latin, meaning double, and mitral-from the Latin, meaning shaped like a mitre) valve in the heart that lies between the left atrium (LA) and the left ventricle (LV).
Called the Mitral valve. Entrance valve that sees only oxygenated blood. Valve that prevents the backflow of blood from the left ventricle. Atrioventricular valve between the left atrium and the left ventricle.