(Redirected from Opportunistic infections) An opportunistic infection is an infection caused by pathogens (bacteria, viruses, fungi, or protozoa) that take advantage of an opportunity not normally available, such as a host with a weakened immune system, an altered microbiota (such as a disrupted gut flora), or breached integumentary barriers.
If someone is described as being 'rough around the edges' it means they are generally good but have a few faults on the outside. Rough around the edges has many meanings: Worn out; Not polished or refined; Not great but not bad either; ans Unkempt.
When someone or something is said to be rough around the edges, it means that he/she/it has great potential, but lacks polish.. It's kinda a compliment ... kinda a slam. It's saying that the person or thing in question could be great, but needs work. *Sombra* Â· 9 years ago.