Acetaminophen (Tylenol) liver damage facts. 1  Acetaminophen is a very safe drug when taken as directed, even for people with liver disease. 2  Liver damage from acetaminophen, which can be severe, can result either from an overdose or from regular doses that are taken while drinking alcohol. Most cases of acetaminophen-induced liver injury are caused by an intentional or suicidal overdose.
Pioglitazone is an oral diabetes medicine that helps control blood sugar levels. Pioglitazone is for people with type 2 diabetes. Pioglitazone is sometimes used in combination with insulin or other medications, but it is not for treating type 1 diabetes.
Pioglitazone (brand name Actos) is a prescription drug of the class thiazolidinedione (TZD) with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes.Actos was the tenth-best selling drug in the U.S. in 2008, with sales exceeding $2.4 billion.ioglitazone cannot be used in patients with a known hypersensitivity to pioglitazone, other thiazolidinediones or any of components of its pharmaceutical forms. It is ineffective and possibly harmful in diabetes mellitus type 1 and diabetic ketoacidosis.