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All patients with stable angina should be treated with aspirin and a statin, unless contraindicated.1 ACE inhibitors are recommended for patients with co-existing conditions that would benefit from this treatment (Table 2). Table 2: Medicines to improve prognosis for stable angina (adapted from Abrams, 2005)2.
A Cochrane review found that for every 1,000 persons treated with a statin for five years, 18 avoid myocardial infarction, angina, or stroke (number needed to treat = 56). This review focused on studies that included fewer than 10% of participants with known cardiovascular disease.