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Usually, receptors are proteins found on or within the membrane. Many different types of molecules can bind to receptors on the cell surface, including hormones. An insulin receptor is an example of a receptor that binds to a hormones, specifically insulin.
In order for insulin to act, it must first bind to specific receptors located on. the plasma membranes of cells (1,2). These receptors were first defined by. virtue of their insulin-binding characteristics, which typically included high. affinity for insulin, rapid and saturable binding, and specificity for insulin.