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My dog has only been on prednisone for 2.5 days (approximately 5 doses) at 60 mg a dose. This was for a low platelet count in case it was autoimmune mediated. The vet has now ruled out autoimmune from lab work that has just come back and wants us to wean him off gradually by reducing the doseage in half amounts. I... show more My dog has only been on prednisone for 2.5 days (approximately 5 doses) at 60 mg a dose.
Your dog is on a massive dose of prednisone, which would be expected to cause polyuria and could lead to overflow incontinence. The maintenance dosage of prednisone for an adult human patient is 5-mg, so your dog should not be on more than that dosage if the drug is being given just for Addison's replacement.hat's what I was hoping you would say (about the weight). The dose of prednisone or prednisonlone that I recommend for dogs with Addison's is between 0.1-0.2 mg/kg/day. That calculates to 1.6-3.2 mg per day.