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an antigenic determinant located in an unexposed region of a molecule so that it is prevented from interacting with receptors on lymphocytes, or with antibody molecules, and is unable to induce an immune response; it may appear following stereochemical alterations of molecular structure.
An antigen is a substance that can invoke an immune response. While an antibody is the immune system's response to an antigen. Antibodies, act by directly neutralizing the antâ¦igen and/or bind to the antigen and signaling marcophages to phagocytose the antigen.