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an antigenic determinant located in an unexposed region of a molecule so that it is prevented from interacting with receptors on lymphocytes, or with antibody molecules, and is unable to induce an immune response; it may appear following stereochemical alterations of molecular structure.
ANTIGEN - A molecule which can be specifically bound by an antibody (typically a. protein or carbohydrate recognized as foreign). EPITOPE (= â antigenic determinantâ =  antigenic specificity) - The minimum. target structure on an antigen which is bound by a particular antibody molecule. A. particular antigen molecule may (and generally does) bear many different epitopes or. âdeterminantsâ, each of which can be a target for antibody binding.