In simple linear regression a single independent variable is used to predict the value of a dependent variable. In multiple linear regression two or more independent variables are used to predict the value of a dependent variable. The difference between the two is the number of independent variables.
Watching for Systemic Symptoms. 1  1. Watch from swollen glands. Serious cases of cellulitis will spread beyond the initially infected region to become systemic and impact the rest of the body. 2  2. Notice if you experience fever and/or chills.
If there is high fever, chills, severe pain, no response to oral medicines; hospitalization may be required. Sepsis: It is probably the most serious and life endangering complication of Cellulitis. Sepsis is the systemic infectious condition where infection has spread in full body through blood.