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an antigenic determinant located in an unexposed region of a molecule so that it is prevented from interacting with receptors on lymphocytes, or with antibody molecules, and is unable to induce an immune response; it may appear following stereochemical alterations of molecular structure.
Definition. noun, plural: antigens. Any of the various substances that when recognized as non-self by the adaptive immune system triggers an immune response, stimulating the production of an antibody that specifically reacts with it. Supplement