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myasthenia gravis myasthenia gravÂ·is (grÄv'Ä­s) n. A disease characterized by progressive fatigue and generalized weakness of the skeletal muscles, especially those of the face, neck, arms, and legs, caused by impaired transmission of nerve impulses following an autoimmune attack on acetylcholine receptors. Also called Goldflam disease.
Definition. Myasthenia gravis (MG) is the most commonly occurring disorder of neuromuscular junction transmission and is characterized by weakness and fatigue of skeletal muscles. It is a T-cell dependent antibody-mediated autoimmune disease.Back to Top.yasthenia gravis (MG) is the most commonly occurring disorder of neuromuscular junction transmission and is characterized by weakness and fatigue of skeletal muscles.