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Indian Journal of Biotechnology. Vol 7, July 2008, pp 341-348. Enhanced production of streptomycin and hydrolytic enzymes by Streptomyces. griseus strains using different types of organic solvents and detergent compounds. Kamal Y I El-shahed*, Ahmed I El-Diwany and Hassan M M Awad. National Research Center, Chemistry of Natural and Microbial Products Department, Dokki-Cairo-Egypt.
Structure of the Month: Beta-lactamase Enzyme Structures. Beta-lactamases are enzymes produced by some Gram-negative and Gram-positive bacteria and are responsible for resistance to a broad class of-beta-lactam antibiotics, including penicillin.There are several groups and classes of beta-lactamases that result in antibiotic resistance.For example, several class C beta-lactamases result in cephalosporin resistance and some class A beta-lactamases confer resistance to oxyimino-cephalosporins, cephamycins and carbapenems.Two different beta â lactamase structures have recently been determined by the Center for Structural Genomics of Infectious Diseases.or example, several class C beta-lactamases result in cephalosporin resistance and some class A beta-lactamases confer resistance to oxyimino-cephalosporins, cephamycins and carbapenems. Two different beta â lactamase structures have recently been determined by the Center for Structural Genomics of Infectious Diseases.