In simple linear regression a single independent variable is used to predict the value of a dependent variable. In multiple linear regression two or more independent variables are used to predict the value of a dependent variable. The difference between the two is the number of independent variables.
Watching for Systemic Symptoms. 1  1. Watch from swollen glands. Serious cases of cellulitis will spread beyond the initially infected region to become systemic and impact the rest of the body. 2  2. Notice if you experience fever and/or chills.
Additional symptoms. Cellulitis can also cause additional symptoms that may develop before or alongside the changes to your skin. Occasionally the infection can spread to other parts of the body, such as the deeper layers of tissue, blood, muscle and bone. This can be very serious and potentially life threatening.