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From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. For example, the epitope is the specific piece of the antigen to which an antibody binds. The part of an antibody that binds to the epitope is called a paratope.
In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism. Sometimes antigens are part of the host itself in an autoimmune disease. Antigens are targeted by antibodies. Each antibody (immune response) is specifically produced by the immune system to match an antigen after cells in the immune system come into contact with it; this allows a precise identification/matching of the antigen and the initiation of a tailored response.