XYLITOL Side Effects & Safety. Xylitol is safe in the amounts found in foods. It seems safe as a medicine for most adults in amounts up to about 50 grams per day. Avoid higher doses. There is some concern that extremely high doses for long periods of time (more than three years) can cause tumors.
Applying the patches for a longer time or using more than 3 patches at a time could result in. increased absorption of lidocaine and high blood concentrations, leading to serious side. effects. Lidocaine toxicity could be expected at lidocaine blood concentrations above 5 Âµg/mL. (1). Off Label Uses: Neuropathic pain: Lidoderm patches have been shown to be effective in treating neuropathic. pain of various types as monotherapy and as adjunctive therapy to an analgesic regimen.
Patients generally reported a decrease in their pain with minimal side effects. The effects of lidocaine on knee pain were also assessed in a 2008 study that used 143 patients with arthritis of the knee. These study subjects tried lidocaine patches in comparison with oral Celebrex for 12 weeks of treatment for pain. In this study, no difference was found between the two treatments, indicating that patients can expect the same level of relief from Lidoderm as Celebrex.