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OPANAÂ® ER is an opioid agonist indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Limitations of Use.
Generic versions are made by manufacturers such as Actavis Elizabeth, LLC, and Global Pharmaceuticals. In December 2011, a new version of Opana ER was approved. This new version is supposedly more resistant to crushing, making it less likely to be abused.