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A decongestant (or nasal decongestant) is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract.The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed efficacy).These are alpha-agonists which on topical application as dilute solution (0.05-0.1%) produce local vasoconstriction.he active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed efficacy). These are alpha-agonists which on topical application as dilute solution (0.05-0.1%) produce local vasoconstriction.
All products from the makers of SUDAFEDÂ® contain a nasal decongestant, either pseudoephedrine or phenylephrine. These medicines act on the nasal passages to narrow blood vessels that are causing nasal congestion. When the blood vessels in the nose and sinus region narrow, tissue shrinks to allow the normal flow of air and mucus. Decongestants act on the nasal passages to narrow blood vessels in the nose and sinus region that cause congestion.