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1. karyotype-the appearance of the chromosomal makeup of a somatic cell in an individual or species (including the number and arrangement and size and structure of the chromosomes). physical composition, composition, make-up, makeup, constitution-the way in which someone or something is composed. Translations.
Analysis of a Karyotype. It is often easier to understand a karyotype if a picture is taken. A karyogram is a photograph of an organism's chromosomes, in which the chromosomes have been sorted and arranged by size. Humans have a total of 46 chromosomes (23 from each parent), which you can see in the karyograms.he number and appearance of chromosomes vary among species. A karyotype is the number, size, and shape of chromosomes in an organism. To determine the karyotype of an organism, scientists must follow these steps: 1  Collect a cell from an individual.