The influx and outflux of ions (through ion channels during neurotransmission) will make the inside of the target neuron more positive (hence, de-polarized). When this depolarization reaches a point of no return called a threshold, a large electrical signal is generated. This is the action potential.
Pico Rivera, California. Pico Rivera is a city located in southeastern Los Angeles County, California, United States. The city is situated approximately 11 miles (18 km) southeast of downtown Los Angeles, on the eastern edge of the Los Angeles basin, and on the southern edge of the area known as the San Gabriel Valley.
Indio is a city in Riverside County, California, United States, located in the Coachella Valley of Southern California 's Colorado Desert region. It lies 23 miles (37 km) east of Palm Springs, 77 miles (124 km) east of Riverside, and 127 miles (204 km) east of Los Angeles. It is about 98 miles (158 km) north of Mexicali, Baja California on the U.S.-Mexican border. The word Indio is Spanish for Indian.