Social Security Timeline. 1  1935 The 37-page Social Security Act signed August 14 by President Franklin D. Roosevelt. 2  1937 First Social Security Cards issued by post offices, over 20 million issued in first year. 3  1937 Ernest Ackerman receives first lump-sum payout (of 17 cents) in January.
The proportion of subjects who permanently discontinued treatment due to adverse events was 0%, less than 1%, and 1% for subjects receiving Harvoni for 8, 12, and 24 weeks, respectively. The most common adverse reactions (at least 10%) were fatigue and headache in subjects treated with 8, 12, or 24 weeks of Harvoni.
However, Harvoni can interact with other medications, and in some cases this can worsen the side effects caused by those drugs. For example, Harvoni can raise the levels of rosuvastatin (Crestor) in the blood, increasing the risk of muscle pain and damage. This, in turn, can lead to liver and kidney problems. While you are taking Harvoni, if you develop any side effects that concern you or don't go away, be sure to tell your doctor.