Base is used broadly in both literal and figurative contexts: the wide base of the pyramid; a party seeking to expand its power base. Basis is used in a nonphysical sense: Healthy scepticism is the basis of all accurate observation (Arthur Conan Doyle).
Omega-3 fats also lower blood pressure and heart rate, improve blood vessel function, and, at higher doses, lower triglycerides and may ease inflammation, which plays a role in the development of atherosclerosis. Several large trials have evaluated the effect of fish or fish oils on heart disease.
We investigated the function of the NR1 subunit of the NMDA receptor and neuronal activation in ARC in mediobasal hypothalamic slices from rats suffering from peripheral inflammatory injury. We found that peripheral inflammation enhanced NR1 phosphorylation and increased neuronal activation in ARC.