In DIC, the processes of coagulation and fibrinolysis are dysregulated, and the result is widespread clotting with resultant bleeding. Regardless of the triggering event of DIC, once initiated, the pathophysiology of DIC is similar in all conditions. One critical mediator of DIC is the release of a transmembrane glycoprotein called tissue factor (TF).
Rigid polyurethane and polyisocyanurate foams will, when ignited, burn rapidly and produce intense heat, dense smoke and gases which are irritating, flammable and/or toxic. As with other organic materials the most significant gas is usually carbon monoxide. Thermal decomposition products from polyurethane foam, consist mainly of carbon monoxide, benzene, toluene, oxides of nitrogen, hydrogen cyanide, acetaldehyde, acetone, propene, carbon dioxide, alkenes and water vapor.
A number of these fires have involved flammable medications in the form of prepping agents (alcohol and alcohol-containing iodophors), eye lubricants, ointments, and wound dressings (tincture of benzoin and collodion). These are just some examples of how flammable some products can be. According to the material safety data sheet for ethyl chloride, it is heavier than air, and the vapors may hug the ground, making distant ignition and flashback possible. Even static electricity may ignite it.