At first, you may barely notice the symptoms of hypothyroidism, such as fatigue and weight gain, or you may simply attribute them to getting older. But as your metabolism continues to slow, you may develop more-obvious signs and symptoms. Hypothyroidism signs and symptom may include: Fatigue.
Studies have estimated that, in the United States, antibiotic resistance adds $20 billion in excess direct health care costs, with additional costs to society for lost productivity as high as $35 billion a year. The use of antibiotics is the single most important factor leading to antibiotic resistance.
The drug, tailor-made for each patient to spur his immune system to attack the tumor, costs $93,000 for a course of treatment, far more than most patients can pay. In the critical clinical trial, it extended median survival time by only four months compared with a placebo. In a second case, Medicare said it would pay for an expensive drug that provides almost no benefit for the typical woman with advanced breast cancer. The drug, Genentechâs Avastin, costs $88,000 a year.