(1) Depositions Upon Consent of Parties: The deposition of an expert witness upon consent of all the parties to a case shall be governed by Rule 74 rather than this Rule, except that the provisions of paragraph (e) of this Rule shall apply to such a deposition.
Lysosomal storage diseases are caused by the accumulation of macromolecules (proteins, polysaccharides, lipids) in the lysosomes because of a genetic failure to manufacture an enzyme needed for their breakdown.
Single gene disorders are caused by DNA changes in one particular gene, and often have predictable inheritance patterns. 1  Over 10,000 human disorders are caused by a change, known as a mutation, in a single gene. Dominant diseases are single gene disorders that occur in the heterozygous state â when an individual has one mutant copy of the relevant gene and one healthy copy.