Eustachian Tube Growth and Development: Anatomy/Function. Protocol Description. This study measures Eustachian tube function and facial growth over time in three groups of children: one with recurrent ear infections, one with chronic middle ear fluid, and one with little past history of otitis media.
Causes of Kartagener syndrome. Kartagener syndrome is caused by a mutation in the DNAI1 gene, which makes a cellular protein required for normal functioning cilia (cilia line the respiratory tract) and sperm motility.
Causes of Li-Fraumeni syndrome Li-Fraumeni syndrome is caused by mutations in the TP53 or CHEK2 genes, both of which produce tumor suppressor genes. The mutations can lead to uncontrolled growth of cells and tumors.