If there is a bulge in something, there is a sudden large increase in it. ...a bulge in aircraft sales. ...the huge bulge of payments due over the next two years. Synonyms: increase, rise, boost, surge More Synonyms of bulge.
Two types of herpes simplex virus infections can cause genital herpes: 1  HSV-1. 2  This is the type that usually causes cold sores or fever blisters around your mouth, though it can be spread to your genital area during oral sex. 3  Recurrences are much less frequent than they are with HSV-2 infection.
HSV-1 and HSV-2 cause herpes, whereas the varicella-zoster virus typically causes chickenpox in children and shingles later in life (Siakallis 2009; Odom 2012; Wolz 2012; Roizman 2001; Odom 2012).owever, they are both caused by members of the herpes virus family. Several members of this virus family can cause disease, but this protocol will focus on herpes simplex virus-1 (HSV-1) , herpes simplex virus-2 (HSV-2) , and varicella-zoster virus.