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From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. For example, the epitope is the specific piece of the antigen to which an antibody binds. The part of an antibody that binds to the epitope is called a paratope.
Antibody â a molecule produced by the body in response to a specific antigen; for example, the presence of the poliovirus in the blood provokes the body to create amino acid molecules (antibodies) to counteract it. Antigen refers to any substance that stimulates the body to make antibodies.