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Rarely do toxins settle in the body. Your body is very good at removing unwanted material, usually via the liver and kidneys. There are no toxins building up in your colon, they don't cause most diseases, and you certainly don't need to detox anything ever. Edit - Naturopaths are crooks and liars, not doctors.
One of the main ways that the body rids itself of toxins is through the liver. In fact, the liver is one of the hardest working organs in our body. It works tirelessly to detoxify our blood, produce the bile needed to digest fat, break down hormones, and store essential vitamins, minerals and iron.