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From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. For example, the epitope is the specific piece of the antigen to which an antibody binds. The part of an antibody that binds to the epitope is called a paratope.
The modern definition encompasses all substances that can be recognized by the adaptive immune system. In the strict sense, immunogens are those substances that elicit a response from the immune system, whereas antigens are defined as substances that bind to specific antibodies.Not all antigens produce an immunogenic response, but all immunogens are antigens. Antigens are usually proteins or polysaccharides.ntigens are any proteinaceous substances that enter into our body and elicit an immune response and antibodies are the substances that are produced by the body's immune system to fight against these anigens.... Shanti Â· 7 years ago. Thumbs up. 2. Thumbs down. 1.