In 2016, you paid $600 interest on a car loan. During 2016, you used the car 60% for business and 40% for personal purposes. You are claiming actual expenses on the car. You can only deduct $360 (60% Ã $600) for 2016 on Schedule C or C-EZ. The remaining interest of $240 is a nondeductible personal expense.
A nonsense mutation is a point mutation that introduces a premature stop codon into the part of the gene that encodes a protein. A stop codon is like a period at the end of a sentence: it instructs the ribosome to stop making the protein.
However, these mistakes are rare, and the cell has repair mechanisms that can repair some damage. - Sometimes a permanent change occurs in a cell's DNA and this is called a mutation. - Because a mutation in a gene causes a change in the protein that is made, the enzyme is nonfunctional. Types of mutations - Mutations can range from changes in a single base pair in the coding sequence of DNA to the deletions of large pieces of chromosomes. - Point mutations involve a chemical change in just one base pair and can be enough to cause a genetic disorder. - A point mutation in which one base is exchanged for another is called a substitution. - Most substitutions are missense mutations, where the DNA code is altered so that it codes for the wrong amino acid. - Other substitutions, called nonsense mutations, change the codon for an amino acid to a stop codon. Nonsense mutations cause translation to terminate early. Nearly all nonsense mutations lead to proteins that cannot function normally. - Another type of mutation that can occur involves the gain or loss of a nucleotide in the DNA sequence.