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10 Common Symptoms of a Blood Clot. Blood clots typically form deep within the veins of the legsâdeep vein thrombosis (DVT). However, the scary part is that most times blood clots can go undetected, resulting in pulmonary embolism and death when leg clots break free and lodge in the lungs. 1. Exhaustion or unexplained fatigue.
1 A blood clot is a mass formed by platelets and fibrin in the blood to stop bleeding. 2  There are a variety of risk factors and illness that can lead to blood clot formation. 3  Causes of blood clots may include: 4  certain heart conditions, 5  pregnancy, 6  prolonged immobility,7  smoking, 8  certain medications, 9  surgery, and. Blood clots can cause heart attack or stroke; or pain, swelling, redness and tenderness in the area of the clot. 2  The diagnosis is suggested by the history and physical examination and often confirmed with an imaging test. 3  Treatment may require surgery, anti-coagulation medications, or a combination of the two.