In DIC, the processes of coagulation and fibrinolysis are dysregulated, and the result is widespread clotting with resultant bleeding. Regardless of the triggering event of DIC, once initiated, the pathophysiology of DIC is similar in all conditions. One critical mediator of DIC is the release of a transmembrane glycoprotein called tissue factor (TF).
Rigid polyurethane and polyisocyanurate foams will, when ignited, burn rapidly and produce intense heat, dense smoke and gases which are irritating, flammable and/or toxic. As with other organic materials the most significant gas is usually carbon monoxide. Thermal decomposition products from polyurethane foam, consist mainly of carbon monoxide, benzene, toluene, oxides of nitrogen, hydrogen cyanide, acetaldehyde, acetone, propene, carbon dioxide, alkenes and water vapor.
Flammable and combustible liquids such as solvents, paint thinners are some of the most hazardous chemicals used on a regular basis. You are han-dling flammable and combus-tible liquids every time you fill your carâs gas tank, thin paint with turpentine, or start a bar-becue with lighter fluid. At work, flammable and combustible liquids are used as solvents, cleaners, fuels, processing aids, and raw materials - sometimes in large quantities. There are no training require-ments in OSHAâs standard on flammable and combustible liquids, but you do need training on the hazards of these chemicals to meet the requirements of the hazard