Although the exact mechanism of action is unknown, pregabalin selectively binds to alpha2delta (A2D) subunits of presynaptic voltage-dependent calcium channels (VDCCs) located in the central nervous system (CNS).
Hexane /ËhÉkseÉªn/ is an alkane of six carbon atoms, with the chemical formula C 6 H 14. typical laboratory use of hexanes is to extract oil and grease contaminants from water and soil for analysis. Since hexane cannot be easily deprotonated, it is used in the laboratory for reactions that involve very strong bases, such as the preparation of organolithiums.
Commercial hexane contains a mixture of hexane isomers (n-hexane, 2-methyl pentane, 3-methyl pentane, 2,3-dimethylbutane), cyclohexane, methyl cyclopentane,pentane and heptane isomers The n-hexane content varies from 20 to 80%. (IPCS 1991)