In E. coli the main enzyme is DNA polymerase III and the enzyme that replaces the RNA primer with DNA is DNA polymerase I. When the RNA primer has been replaced with DNA, there is a gap between the two Okazaki fragments and this is sealed by DNA ligase.
Little Richard's Tutti Frutti (1955) was included in the National Recording Registry of the Library of Congress in 2010, which stated that his unique vocalizing over the irresistible beat announced a new era in music..
Originally recorded by McDonald's rock group The Doobie Brothers for their seventh studio album, Livin' on the Fault Line (1977), the song was made famous by Simon herself when she recorded it for her seventh studio album, Boys in the Trees (1978). It was recorded in Finnish by Finnish singer Maarit for her 1978 album Siivet saan, retitled Yhteen kuulutaan. 2  Los Hooligans, a traditional ska band from Fresno, California, covered the song on their Mafioso Ska CD released in 2006 with lead vocals sung by Randy Young.