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1. karyotype-the appearance of the chromosomal makeup of a somatic cell in an individual or species (including the number and arrangement and size and structure of the chromosomes). physical composition, composition, make-up, makeup, constitution-the way in which someone or something is composed. Translations.
Karyotype is a test to identify and evaluate the size, shape, and number of chromosomes in a sample of body cells. Results of a karyotype test are usually available within 1 to 2 weeks. There are 46 chromosomes that can be grouped as 22 matching pairs and 1 pair of sex chromosomes (XX for a female and XY for a male).