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myasthenia gravis myasthenia gravÂ·is (grÄv'Ä­s) n. A disease characterized by progressive fatigue and generalized weakness of the skeletal muscles, especially those of the face, neck, arms, and legs, caused by impaired transmission of nerve impulses following an autoimmune attack on acetylcholine receptors. Also called Goldflam disease.
Knowledge center. In Myasthenia gravis, also known as Goldflam disease, a neuromuscular disease, the muscles under our voluntary control become easily tired and weak because there is a problem with how the nerves stimulate the contraction of muscles.yasthenia gravis (MG) is distinguished from congenital myasthenic syndromes (which have similar symptoms) in that MG responds well to immunosuppressive interventions, while congenital myasthenic syndromes do not. Myasthenia gravis more commonly occurs in women under 40 years and men over 60.