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myasthenia gravis myasthenia gravÂ·is (grÄv'Ä­s) n. A disease characterized by progressive fatigue and generalized weakness of the skeletal muscles, especially those of the face, neck, arms, and legs, caused by impaired transmission of nerve impulses following an autoimmune attack on acetylcholine receptors. Also called Goldflam disease.
Myasthenia gravis, a rare, chronic disorder that causes weakness and rapid muscle fatigue. Muscle weakness that is slowly getting worse requires a visit to a doctor. Sudden muscle weakness and loss of function in one area of the body can indicate a serious problem within the brain (such as a stroke or transient ischemic attack) or spinal cord or with a specific nerve in the body.