The influx and outflux of ions (through ion channels during neurotransmission) will make the inside of the target neuron more positive (hence, de-polarized). When this depolarization reaches a point of no return called a threshold, a large electrical signal is generated. This is the action potential.
Pico Rivera, California. Pico Rivera is a city located in southeastern Los Angeles County, California, United States. The city is situated approximately 11 miles (18 km) southeast of downtown Los Angeles, on the eastern edge of the Los Angeles basin, and on the southern edge of the area known as the San Gabriel Valley.
Imperial County is a county located in the U.S. state of California. As of the 2010 census, the population was 174,528. The county seat is El Centro. Established in 1907, it was the last county to be formed in California. Imperial County comprises the El Centro, CA Metropolitan Statistical Area. It is also part of the Southern California border region, the smallest but most economically diverse region in the state. It is located in the Imperial Valley, in the far southeast of California, bordering both Arizona and Mexico.