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The signs and symptoms of acute coronary syndrome, which usually begin abruptly, include the following: Chest pain (angina) or discomfort, often described as aching, pressure, tightness or burning. Pain radiating from the chest to the shoulders, arms, upper abdomen, back, neck or jaw. Nausea or vomiting. Indigestion.
Cardiovascular symptoms of MCAS. MCAS patients often have a number of cardiovascular symptoms. In true mast cell disease fashion, these symptoms often represent both ends of the spectrum. Heart palpitations are the most common cardiac complaint, with true rhythmic abnormalities being fairly rare.