The cells of the adaptive immune system are special types of leukocytes, called lymphocytes. B cells and T cells are the major types of lymphocytes and are derived from hematopoietic stem cells in the bone marrow.
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The symptoms may vary depending on the location of the ulcer: 1  Duodenal ulcers often cause a gnawing pain in the upper stomach area several hours after a meal, and patients can often relieve the pain by eating. 2  Many patients also have heartburn. 3  Gastric ulcers may cause a dull, aching pain, often right after a meal.