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This small nucleus contains almost half of all the brain neurons that use norepinephrine as a neurotransmitter. The locus coeruleus also projects its axons to those parts of the brain that may be associated with panic disorders (the amygdala, hippocampus, septum, cortex, brainstem, reticular formation, etc). Stimulating an animal's locus coeruleus, like stimulating its amygdala, produces anxiety behaviours.
Anxiety is seen as a psychological condition, but the causes of anxiety are far more complex. Anxiety can be caused muscle energy-you can genuinely get mental stresses simply because you're not moving your muscles enough. Anxiety can also be caused by nutrition. Anxiety can be caused by thousands of different things. So it should come as no surprise that hormonal imbalances may cause anxiety as well. The term hormonal imbalance has a variety of meanings, but it's also very clear that it can lead to anxiety.