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This small nucleus contains almost half of all the brain neurons that use norepinephrine as a neurotransmitter. The locus coeruleus also projects its axons to those parts of the brain that may be associated with panic disorders (the amygdala, hippocampus, septum, cortex, brainstem, reticular formation, etc). Stimulating an animal's locus coeruleus, like stimulating its amygdala, produces anxiety behaviours.
There are two reasons that fear exists. First, because anxiety causes fears - it's a symptom of the anxiety itself. Second, because anxiety can also lead to heart and brain symptoms that are considered identical to actual diseases and illnesses. In this article, we'll explore some of the many neurological symptoms of anxiety.