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myasthenia gravis myasthenia gravÂ·is (grÄv'Ä­s) n. A disease characterized by progressive fatigue and generalized weakness of the skeletal muscles, especially those of the face, neck, arms, and legs, caused by impaired transmission of nerve impulses following an autoimmune attack on acetylcholine receptors. Also called Goldflam disease.
What is myasthenia gravis (MG)? Myasthenia gravis (meye-uhss-THEEN-ee-uh GRAV uhss) (MG) is an autoimmune disease that weakens the muscles. The name comes from Greek and Latin words meaning grave muscle weakness. But most cases of MG are not as grave as the name implies. In fact, most people with MG can expect to live normal lives.