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1. karyotype-the appearance of the chromosomal makeup of a somatic cell in an individual or species (including the number and arrangement and size and structure of the chromosomes). physical composition, composition, make-up, makeup, constitution-the way in which someone or something is composed. Translations.
A karyotype will consist of all the homologous pairs of chromosomes and also one pair of chromosomes representing the sex of the organism (male/female). In Humans, a karyotype â¦ will consist of 22 homologous pairs of chromosomes and 1 pair of either XX or XY chromosomes.