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myasthenia gravis myasthenia gravÂ·is (grÄv'Ä­s) n. A disease characterized by progressive fatigue and generalized weakness of the skeletal muscles, especially those of the face, neck, arms, and legs, caused by impaired transmission of nerve impulses following an autoimmune attack on acetylcholine receptors. Also called Goldflam disease.
Myasthenia gravis is a neuromuscular disorder that causes weakness and fatigue in the muscles that control voluntary movement in the body.The weakness is caused by a disruption in the communication between the muscles and the nerves that control them.hile myasthenia gravis can affect any voluntary muscles in the body, most patients will first notice its effects in the muscles that control the movement of the eyes and eyelids. The weakening of these muscles can result in droopy eyelids, double vision and partial paralysis of eye movements.