Base is used broadly in both literal and figurative contexts: the wide base of the pyramid; a party seeking to expand its power base. Basis is used in a nonphysical sense: Healthy scepticism is the basis of all accurate observation (Arthur Conan Doyle).
Omega-3 fats also lower blood pressure and heart rate, improve blood vessel function, and, at higher doses, lower triglycerides and may ease inflammation, which plays a role in the development of atherosclerosis. Several large trials have evaluated the effect of fish or fish oils on heart disease.
Cimzia (certolizumab pegol), Enbrel (etanercept), Humira (adalimumab), Remicade (infliximab) and Simponi (golimumab) are drugs that block TNF-alpha. TNF-alpha is a cytokine, or a protein, that prompts the body to create inflammation. In psoriasis and psoriatic arthritis, there is excess production of TNF-alpha in the skin or joints. That leads to the rapid growth of skin cells and/or damage to joint tissue.