DOSAGE AND ADMINISTRATION. Methimazole is administered orally. The total daily dosage is usually given in 3 divided doses at approximately 8-hour intervals. Adult-The initial daily dosage is 15 mg for mild hyperthyroidism, 30 to 40 mg for moderately severe hyperthyroidism, and 60 mg for severe hyperthyroidism, divided into 3 doses at 8-hour intervals.
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