Social Security Timeline. 1  1935 The 37-page Social Security Act signed August 14 by President Franklin D. Roosevelt. 2  1937 First Social Security Cards issued by post offices, over 20 million issued in first year. 3  1937 Ernest Ackerman receives first lump-sum payout (of 17 cents) in January.
The proportion of subjects who permanently discontinued treatment due to adverse events was 0%, less than 1%, and 1% for subjects receiving Harvoni for 8, 12, and 24 weeks, respectively. The most common adverse reactions (at least 10%) were fatigue and headache in subjects treated with 8, 12, or 24 weeks of Harvoni.
When Gilead Sciences introduced an upgraded drug called Harvoni (90mg ledipasvir/400mg sofosbuvir) on the market, the main issue was the Harvoni cost on the US market, and what cost of Harvoni pills can other countries in Europe and Asia expect. Harvoni price in the USA was set to $94,500 per 12-week treatment.