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1 Urethral cancer is a disease in which malignant (cancer) cells form in the tissues of the urethra, the tube that carries urine from the bladder to outside the body. It is a rare cancer that occurs more often in women than in men.  Squamous cell carcinoma is the most common type of urethral cancer.
Tumors of the renal calyces, renal pelvis and ureters start in the layer of tissue that lines the bladder and the upper urinary tract, called the urothelium. Cancer that starts in the urothelium is called urothelial (or transitional cell) cancer. This is the most common type of cancer found in the bladder, as well. Because many of the organs in the urinary system share common cells, cancers found in these organs often look and act alike. Parts of the kidney. Image Â© 2003 Fairman Studios, LLC.