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Interactions With Medications. Even though vitamin B-12 is safe if you take too much, it can interact negatively with certain medications. Chloramphenicol, a type of antibiotic, affects how your body responds to B-12.Even though you're taking a large dose of B-12, the medication limits the vitamin's function.ost vitamins and minerals can be toxic if you take too much. However, vitamin B-12 is a little different. Your system only absorbs a small amount at a time and gets rid of what it doesn't need, which means it's generally safe, even if you take too much.
Vitamin B12 can help your body to reduce your homocysteine levels. And because homocysteine is one thing that can cause heart disease, vitamin B12 will be helping you to reduce your chance of getting it. Taking a Vitamin B12 Supplement. If you feel as though vitamin B12 can help you and your body.he truth is that if you get enough vitamin B12 in your daily diet, you don't need to take any additional vitamin B12 supplements. But, you may need to take vitamin B12 if you are not getting enough of it. Here are some signs that you may need to take a vitamin B12 supplement: