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Common glucocorticoids include prednisone, dexamethasone, and hydrocortisone. While glucocorticoids are widely used as drugs to treat various inflammatory conditions, prolonged glucocorticoid use may have adverse side effects such as immunosuppression, fluid shifts, brain changes, and psychological changes.
Glucocorticoids are potent anti-inflammatory agents and their administration results in a wide range of effects on inflammatory and immunologically mediated disease processes. The precise mechanisms by which glucocorticoids impair the human immune response are unknown.