1 Skin conditions and rashes. 2  Many skin conditions itch, including eczema (dermatitis), psoriasis, scabies, lice, chickenpox and hives. 3  The itching usually affects specific areas and is accompanied by other signs, such as red, irritated skin or bumps and blisters. 4  Internal diseases. Skin conditions and rashes. 2  Many skin conditions itch, including eczema (dermatitis), psoriasis, scabies, lice, chickenpox and hives. 3  The itching usually affects specific areas and is accompanied by other signs, such as red, irritated skin or bumps and blisters. 4  Internal diseases.
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