âThatâs something we can test. If it does, caspase-1 inhibitors mightâand I emphasize mightâbecome a component of a curative cocktail.â G. Doitsh et al., âCell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection,â Nature, doi:10.1038/nature12940, 2013.
Decades ago it was believed that a cascade of enzymes controls the activity of HMG-CoA reductase: an HMG-CoA reductase kinase was thought to inactivate the enzyme, and the kinase in turn was held to be activated via phosphorylation by HMG-CoA reductase kinase kinase.
exists and is an alternate of . Each hormone is a signal for the cell, that a specific chemical reaction must be done. As the molecules of hormones attach to cell receptors, adenylyl cyclase (transmembrane protein) is activated. Activated Adenylyl cyclase modifies ATP to form cyclic adenine monophosphate (cAMP). cAMP then activates various enzymes that catalyse the necessary reaction. Therefore, cAMP is an intermedium between the hormone and the result (chemical reaction).