Wholesale cost from Ford on a radiator for a 2006-2009 Explorer runs as high as $470 for the part alone, and labor costs can take replacing the unit much, much higher.
SAM-e, which is sold as a dietary supplement, is either made from fermented yeast or totally synthesized. 1  SAM-e is produced by methionine (a sulfur-containing amino acid) and ATP (adenosine triphosphate) in the body.
SAM-e can also trigger an allergic reaction in some people. Risks. If you have any medical issues, check with a doctor before you start using SAM-e supplements. SAM-e might not be safe for people with conditions such as bipolar disorder, Parkinson's disease, and diabetes.