Abby Jackson Â· Business Insider 01 Sep 2017. South Africa just saw its credit rating downgraded after two of the three major ratings agencies issued depressing assessments of the state of the countryâs economy.
Mastocytosis (say âmas-toe-sigh-toe-sisâ) is a rare disease of the skin (the most common form), or of other parts of the body (very rare), like the stomach, the intestines and the bone marrow.It's caused by having too many mast cells. Mast cells are a kind of blood cell.Mastocytosis can occur at any age.astocytosis (say âmas-toe-sigh-toe-sisâ) is a rare disease of the skin (the most common form), or of other parts of the body (very rare), like the stomach, the intestines and the bone marrow.
1 MCAS-synonym: mast cell activation disorder (MCAD) - is characterised by the accumulation of genetically altered mast cells and/or abnormal release of mast cell mediators, affecting functions in potentially every organ system, particularly the skin, gastrointestinal tract, and cardiovascular and nervous systems. In systemic mastocytosis with associated haematological non-mast cell lineage disease (SM-AHNMD), the prognosis depends on the course of the associated haematological disorder. 2  Agressive systemic mastocytosis and mast cell leukaemia have a poorer prognosis.