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Potential side effects of common diabetes drugs*. 1  Sulfonylureas: low blood sugar, upset stomach, skin rash or itching, weight gain. 2  Biguanides/Metformin: sickness with alcohol, kidney complications, upset stomach, tiredness or dizziness, metal taste. 3  Alpha-glucosidase inhibitors: gas, bloating and diarrhoea.
How diabetes affects the skin. Diabetes affect on the skin is usually a result of its affect on the nerves and circulation which can lead to dry skin, slow healing of cuts, burns and wounds, fungal and bacterial infections and loss of feeling in the foot.iabetes affects our blood vessels and nerves and therefore can affect any part of the body. However, certain parts of our body are affected more than other parts.