The steady-state plasma concentration that is reached is 4.0 mg/L, so TC = 4.0 mg/L loading dose = 8 mg/hour Vd = loading dose/TC Vd = 8 mg/hour / 4 mg/L = 2 L What is the volume of distribution? CL = kVd t1/2 = 0.7 / k t1/2 = 0.7 Vd/CL Vd = CL * t1/2 / 0.7 Note that Clearance at a steady state can be calculated by: Dose <steady state> = CL * TC, so
As a regulator of sensory information, the thalamus also controls sleep and awake states of consciousness. Function: The thalamus is involved in several functions of the body including: 1  Motor Control. 2  Receives Auditory, Somatosensory and Visual Sensory Signals. 3  Relays Sensory Signals to the Cerebral Cortex.
The Quick Facts. Location: Part of the forebrain, below the corpus callosum. Function: Responsible for relaying information from the sensory receptors to proper areas of the brain where it can be processed. The thalamus is similar to a doctor that diagnoses, or identifies, a patient's disease or sickness. It diagnoses different sensory information that is being transmitted to the brain including auditory (relating to hearing or sound), visual, tactile (relating to touch), and gustatory (relating to taste) signals. After that, it directs the sensory information to the different parts and lobes of the cortex.