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Genetic engineering is used to create animal models of human diseases. Genetically modified mice are the most common genetically engineered animal model. They have been used to study and model cancer (the oncomouse), obesity, heart disease, diabetes, arthritis, substance abuse, anxiety, aging and Parkinson disease.
GMOs, or genetically modified organisms are organisms whose genetic material has been altered using genetic engineering. Genetic engineering is the modification of an organism's phenotype by altering its genetic make-up. Genetic engineering is primarily performed by simple mating or gene recombination.