Thrombocytosis is defined as a platelet count above the upper limit of the normal range (450 x 10 9 /L in adults). This article aims to outline diagnosis, investigation and management of patients with thrombocytosis and to highlight possible complications.
  Dr Edward Jenner discovered the vaccine in 1796 and published his findings in 1798. Edward Jenner invented the vaccine for small pox in 1798.He  prepared the vaccine f â¦ rom the cow pox virus. His discovery could  save more lives than any other medical discovery. Dr Edward Jenner discovered the vaccine in 1796 and published his findings in 1798. Edward Jenner invented the vaccine for small pox in 1798. He  prepared the vaccine f â¦ rom the cow pox virus.
Successful use of smallpox vaccine led to the gradual reduction of smallpox cases. The last U.S. wild smallpox case occurred in 1949. After intensive vaccination campaigns in the 1960s and 1970s, the last case of wild smallpox in the world occurred in 1977.