Wholesale cost from Ford on a radiator for a 2006-2009 Explorer runs as high as $470 for the part alone, and labor costs can take replacing the unit much, much higher.
SAM-e, which is sold as a dietary supplement, is either made from fermented yeast or totally synthesized. 1  SAM-e is produced by methionine (a sulfur-containing amino acid) and ATP (adenosine triphosphate) in the body.
SAM-e Side Effects Nausea, insomnia, and loss of appetite are some of the more common problems reported by people taking SAM-e. These problems are more likely to occur with a higher dosage of the supplement. Several less common -- but potentially serious -- side effects of SAM-e are also possible and require immediate medical attention, including restlessness, panic attacks, and suicidal thoughts or behavior.