Hand cramping can occur for many reasons and cause significant discomfort in some people. Often, hand cramps are caused by muscle spasms, which are described as an uncontrollable or involuntary muscle contraction. These spasms or contractions do not allow the muscle to become relaxed and can become excruciating in some cases.
Serum levels of prolactin may increase as a consequence of epileptic seizures. The hormone release is caused by the propagation of epileptic activity, usually from the temporal lobe to the hypothalamic-pituitary axis.
1 Breast stimulation can modestly increase the amount of prolactin in the blood. 2  Chest wall trauma (for example, an injury from a car steering wheel after an accident) can lead to increased levels of prolactin.  Marijuana use is also a well documented cause of elevated levels of prolactin.