Most drugs found to cause nephrotoxicity exert toxic effects by one or more common pathogenic mechanisms. These include altered intraglomerular hemodynamics, tubular cell toxicity, inflammation, crystal nephropathy, rhabdomyolysis, and thrombotic microan-giopathy.
Leclercia adecarboxylata is an opportunistic human pathogen that phenotypically resembles Escherichia coli. The natural susceptibilities of 101 Leclercia strains to 70 antimicrobial agents were investigated. MICs were determined with a microdilution procedure in cation-adjusted MuellerâHinton broth (all strains) and IsoSensitest broth (some strains).
Pasteurella is a genus of Gram-negative, facultatively anaerobic bacteria. Pasteurella species are non motile and pleomorphic. Most species are catalase-and oxidase-positive.The genus is named after the French chemist and microbiologist, Louis Pasteur, who first identified the bacteria now known as Pasteurella multocida as the agent of chicken cholera.ommon symptoms of pasteurellosis in humans include swelling, cellulitis, and bloody drainage at the site of the wound. Infections may progress to nearby joints where it can cause swelling and arthritis. Pasteurella spp. are generally susceptible to chloramphenicol, the penicillins, tetracycline, and the macrolides.