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The vaccines have been shown to offer 100 percent protection against the development of cervical pre-cancers and genital warts caused by the HPV types in the vaccine, with few or no side effects. The protective effects of the vaccine are expected to last a minimum of 4.5 years after the initial vaccination.
HPV vaccine produces the strongest immune response in preteens. To work best, the HPV vaccines should be given at age 11 or 12. The vaccines are given in a series of shots. The American Cancer Societyâs recommendations for HPV vaccine use. Routine HPV vaccination for girls and boys should be started at age 11 or 12. The vaccination series can be started as early as age 9. HPV vaccination is also recommended for females 13 to 26 years old and for males 13 to 21 years old who have not started the vaccines, or who have started but not completed the series.