At a high level, the certification is split into seven different domains: 1  Monitoring and Metrics (15 percent) 2  High Availability (15 percent) 3  Analysis (15 percent) 4  Deployment and Provisioning (15 percent) 5  Data Management (12 percent) 6  Security (15 percent) 7  Networking (13 percent)
Mitochondrial diseases result from failures of the mitochondria, specialized compartments present in every cell of the body except red blood cells. Mitochondria are responsible for creating more than 90% of the energy needed by the body to sustain life and support growth.When they fail, less and less energy is generated within the cell. Cell injury and even cell death follow.henocopies of Mitochondrial Disease. The converse is also true: different mutations in mtDNA and nDNA can lead to the same diseases. In genetics, these are known as phenocopies. A good example is Leigh syndrome, which can be caused by about a dozen different gene defects.
Furthermore, the different proportions of mutant mitochondrial DNA that result in altered nuclear gene expression correspond to the same proportions of mutations in mitochondrial DNA that are associated with diabetes and autism; brain, heart and muscle disease; or lethal infantile disease.allaceâs current study rests on his investigations into the mysteries of mitochondria for over 40 years. In 1988, he was the first to demonstrate that mitochondrial DNA mutations can cause human disease.