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Pseudogout is caused by the formation of calcium pyrophosphate crystals in the synovial fluid in the joints. Crystals can also deposit in the cartilage, where they can cause damage.seudogout most often affects the knees, but also affects ankles, wrists, and elbows. General symptoms may include: 1  periodic episodes of joint pain. 2  swelling of the affected joint.
When uric acid overflow occurs in the blood, crystals deposit onto the joints and tissues of the body. A great deal of pain and swelling can be caused by gout, which is one of the many forms of arthritis. Many people who are worried they have gout may actually have the condition pseudogout.