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The vaccines have been shown to offer 100 percent protection against the development of cervical pre-cancers and genital warts caused by the HPV types in the vaccine, with few or no side effects. The protective effects of the vaccine are expected to last a minimum of 4.5 years after the initial vaccination.
Safety of HPV vaccine during pregnancy. Currently there are 2 inactive recombinant HPV vaccines available in Canada: a quadrivalent vaccine, which provides protection against HPV types 6, 11, 16, and 18, and a bivalent vaccine, which provides protection against HPV types 16 and 18. combined analysis of 5 randomized controlled trials reported outcomes of 3620 women who, during phase 3 clinical trials, were inadvertently exposed to the quadrivalent HPV vaccine or placebo either during or just before pregnancy.