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Interactions With Medications. Even though vitamin B-12 is safe if you take too much, it can interact negatively with certain medications. Chloramphenicol, a type of antibiotic, affects how your body responds to B-12.Even though you're taking a large dose of B-12, the medication limits the vitamin's function.ost vitamins and minerals can be toxic if you take too much. However, vitamin B-12 is a little different. Your system only absorbs a small amount at a time and gets rid of what it doesn't need, which means it's generally safe, even if you take too much.
Taking too much vitamin B12 can lead to side effects. Knowing the facts before you begin vitamin B12 supplementation can help you to make informed health decisions about the vitamins you choose to take. Consult with your physician before taking B12 supplements to treat a condition. Knowing the facts before you begin vitamin B12 supplementation helps you make informed health decisions and determine if B12 supplements or injections are the right fit for you. Potential Side Effects of Vitamin B12