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Sooo apparently some antibiotics cause a sore tongue. I had strep throat about a week and a half ago and I was prescribed an antibiotic (penicillin) for like 10 days. My strep went away and all but now my tongue is sore when I consume stuff, Especially when I eat any kind of sauce or carbonated drink.
Some likely causes are: 1  Though they donât seem to be caused by bacteria or viruses, they can be triggered by an allergy to bacteria commonly found in the mouth.6 They may occur with viral infections. 2  A fault in the immune system can cause it to attack normal cells in the tongue and mouth.7.