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1 Cystic fibrosis primarily affects the lungs and digestive system. 2  It leads to the production of mucus that is much thicker and more sticky than usual. 3  Cystic fibrosis is a hereditary condition, caused by a defective gene. 4  The cystic fibrosis gene must be present in both parents for a child to have the condition.
Relevance. Rating Newest Oldest. Best Answer: cystic fibrosis is caused by a defect in the channel protein affecting the transport of chlorine molecules. This causes excess salt to be lost in sweat and also causes mucus to thicken up :) this causes thick mucus to clog up lungs and lead to suffocation.IT also causes malnourishment as the mucus prevents food from being absorbed.his causes excess salt to be lost in sweat and also causes mucus to thicken up :) this causes thick mucus to clog up lungs and lead to suffocation. IT also causes malnourishment as the mucus prevents food from being absorbed.