Hand cramping can occur for many reasons and cause significant discomfort in some people. Often, hand cramps are caused by muscle spasms, which are described as an uncontrollable or involuntary muscle contraction. These spasms or contractions do not allow the muscle to become relaxed and can become excruciating in some cases.
Serum levels of prolactin may increase as a consequence of epileptic seizures. The hormone release is caused by the propagation of epileptic activity, usually from the temporal lobe to the hypothalamic-pituitary axis.
Typical antipsychotics block dopamine inhibition of the pituitary and cause prolactin rise. Secretion of prolactin by the pituitary is under inhibitory control via dopamine from the hypothalamus. Interference with dopamine secretion or action leads to an increase in serum prolactin.