The steady-state plasma concentration that is reached is 4.0 mg/L, so TC = 4.0 mg/L loading dose = 8 mg/hour Vd = loading dose/TC Vd = 8 mg/hour / 4 mg/L = 2 L What is the volume of distribution? CL = kVd t1/2 = 0.7 / k t1/2 = 0.7 Vd/CL Vd = CL * t1/2 / 0.7 Note that Clearance at a steady state can be calculated by: Dose <steady state> = CL * TC, so
As a regulator of sensory information, the thalamus also controls sleep and awake states of consciousness. Function: The thalamus is involved in several functions of the body including: 1  Motor Control. 2  Receives Auditory, Somatosensory and Visual Sensory Signals. 3  Relays Sensory Signals to the Cerebral Cortex.
The diencephalon lies above the brain stem and embodies the thalamus and hypothalamus. The thalamus is an important relay station for sensory information, interpreting sensations of sound, smell, taste, pain, pressure, temperature, and touch; the thalamus also regulates some emotions and memory.he diencephalon lies above the brain stem and embodies the thalamus and hypothalamus. The thalamus is an important relay station for sensory information, interpreting sensations of sound, smell, taste, pain, pressure, temperature, and touch; the thalamus also regulates some emotions and memory.