Hand cramping can occur for many reasons and cause significant discomfort in some people. Often, hand cramps are caused by muscle spasms, which are described as an uncontrollable or involuntary muscle contraction. These spasms or contractions do not allow the muscle to become relaxed and can become excruciating in some cases.
Serum levels of prolactin may increase as a consequence of epileptic seizures. The hormone release is caused by the propagation of epileptic activity, usually from the temporal lobe to the hypothalamic-pituitary axis.
During pregnancy, high circulating concentrations of estrogen and progesterone increase prolactin levels by 10- to 20-fold. However, at the same time, estrogen, as well as progesterone, inhibit the stimulatory effects of prolactin on milk production.hysiologic levels of prolactin in males enhance luteinizing hormone-receptors in Leydig cells, resulting in testosterone secretion, which leads to spermatogenesis. Prolactin also stimulates proliferation of oligodendrocyte precursor cells.