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Pseudogout is caused by the formation of calcium pyrophosphate crystals in the synovial fluid in the joints. Crystals can also deposit in the cartilage, where they can cause damage.seudogout most often affects the knees, but also affects ankles, wrists, and elbows. General symptoms may include: 1  periodic episodes of joint pain. 2  swelling of the affected joint.
If the level of uric acid in your body is too high, it can form tiny crystals that collect in your tissues. These can collect in and around your joints in particular. This is what may cause your swelling and pain. When you have pseudogout, the crystals that form aren't uric acid crystals, as they are with 'real' gout.