Dimetapp Paediatric Elixir is contra-indicated in patients sensitive to any of the ingredients and in infants or neonates. It should not be given to patients whose sensitivity to small doses of sympathomimetic substances is manifested by sleeplessness, dizziness, light headaches, weakness, tremulousness or cardiac arrhythmia.
In fact, worrying (or anxiety) can stimulate the release of epinephrine into your system, whereby it will bind with your beta-adrenergic receptors in your liver, causing your blood vessels to constrict and your blood pressure to rise, along with your heart rate (pulse).
While caffeine does not directly bind to any dopamine receptors, it influences the binding activity of dopamine at its receptors in the striatum by binding to adenosine receptors that have formed GPCR heteromers with dopamine receptors, specifically the A 1 âD 1 receptor heterodimer (this is a receptor complex with 1 adenosine A 1 receptor and 1 dopamine D 1 receptor) and the A 2A âD 2 receptor heterotetramer (this is a receptor complex with 2 adenosine A 2A receptors and 2 dopamine D 2 ...