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1 Cystic fibrosis primarily affects the lungs and digestive system. 2  It leads to the production of mucus that is much thicker and more sticky than usual. 3  Cystic fibrosis is a hereditary condition, caused by a defective gene. 4  The cystic fibrosis gene must be present in both parents for a child to have the condition.
Cystic Fibrosis: Introduction. Cystic fibrosis is a chronic, progressive and debilitating disease that affects the lungs, intestines, liver, and pancreas. Cystic fibrosis is caused by a genetic defect that triggers the mucous producing glands of the body to make excessive amounts of abnormally thick and sticky mucus. Cystic fibrosis results in the clogging of the tubes, ducts and air passages of the body with mucus. This leads to serious problems with digestion and breathing.