Hand cramping can occur for many reasons and cause significant discomfort in some people. Often, hand cramps are caused by muscle spasms, which are described as an uncontrollable or involuntary muscle contraction. These spasms or contractions do not allow the muscle to become relaxed and can become excruciating in some cases.
Serum levels of prolactin may increase as a consequence of epileptic seizures. The hormone release is caused by the propagation of epileptic activity, usually from the temporal lobe to the hypothalamic-pituitary axis.
Prolactin-secreting tumors. Overproduction of prolactin from a pituitary tumor (prolactinoma) can cause a decrease in normal levels of sex hormones â estrogen in women and testosterone in men. Excessive prolactin in the blood affects men and women differently.