Dimetapp Paediatric Elixir is contra-indicated in patients sensitive to any of the ingredients and in infants or neonates. It should not be given to patients whose sensitivity to small doses of sympathomimetic substances is manifested by sleeplessness, dizziness, light headaches, weakness, tremulousness or cardiac arrhythmia.
In fact, worrying (or anxiety) can stimulate the release of epinephrine into your system, whereby it will bind with your beta-adrenergic receptors in your liver, causing your blood vessels to constrict and your blood pressure to rise, along with your heart rate (pulse).
Epinephrine bound to Î²-adrenergic receptors on smooth muscle cells of the intestine causes them to relax. Another type of epinephrine receptor, the Î±2-adrenergic receptor, is found on smooth muscle cells lining the blood vessels in the intestinal tract, skin, and kidneys.