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Interactions With Medications. Even though vitamin B-12 is safe if you take too much, it can interact negatively with certain medications. Chloramphenicol, a type of antibiotic, affects how your body responds to B-12.Even though you're taking a large dose of B-12, the medication limits the vitamin's function.ost vitamins and minerals can be toxic if you take too much. However, vitamin B-12 is a little different. Your system only absorbs a small amount at a time and gets rid of what it doesn't need, which means it's generally safe, even if you take too much.
A deficiency of either B6 or B12 can cause anemia, so these vitamins may be taken to treat this condition, which leads to low energy. Adults ages 19 to 50 need 1.3 milligrams of vitamin B6 daily, while older women need 1.5 milligrams and senior men need 1.7 milligrams.ufficient amounts of vitamin B6 and vitamin B12 are needed to stay well and feel your best, but itâs possible to get too much of these vitamins if you take supplements. Taking too much vitamin B6 can be harmful because excess amounts of B6 can cause nerve damage.