Abby Jackson Â· Business Insider 01 Sep 2017. South Africa just saw its credit rating downgraded after two of the three major ratings agencies issued depressing assessments of the state of the countryâs economy.
Mastocytosis (say âmas-toe-sigh-toe-sisâ) is a rare disease of the skin (the most common form), or of other parts of the body (very rare), like the stomach, the intestines and the bone marrow.It's caused by having too many mast cells. Mast cells are a kind of blood cell.Mastocytosis can occur at any age.astocytosis (say âmas-toe-sigh-toe-sisâ) is a rare disease of the skin (the most common form), or of other parts of the body (very rare), like the stomach, the intestines and the bone marrow.
Langerhans cell histiocytosis (LCH) is a rare disease involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes.Clinically, its manifestations range from isolated bone lesions to multisystem disease.angerhans cell histiocytosis (LCH) is a rare disease involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes.