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Potential side effects of common diabetes drugs*. 1  Sulfonylureas: low blood sugar, upset stomach, skin rash or itching, weight gain. 2  Biguanides/Metformin: sickness with alcohol, kidney complications, upset stomach, tiredness or dizziness, metal taste. 3  Alpha-glucosidase inhibitors: gas, bloating and diarrhoea.
In people with diabetic nephropathy, common side effects with losartan include: 1  Diarrhea -- up to 15 percent of people. 2  Fatigue -- up to 14 percent. 3  Anemia -- up to 14 percent. 4  Increase in blood potassium levels -- up to 7 percent.  Low blood pressure -- up to 7 percent.