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The vaccines have been shown to offer 100 percent protection against the development of cervical pre-cancers and genital warts caused by the HPV types in the vaccine, with few or no side effects. The protective effects of the vaccine are expected to last a minimum of 4.5 years after the initial vaccination.
Protection from HPV vaccination is expected to be long-lasting. The best way a person can be sure to get the most benefit from HPV vaccination is to complete all three doses before being exposed to HPV infection. Women should still get regular Pap tests in addition to receiving HPV vaccine.