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Macrophages are important cells of the immune system that are formed in response to an infection or accumulating damaged or dead cells. Macrophages are large, specialized cells that recognize, engulf and destroy target cells. The term macrophage is formed by the combination of the Greek terms makro meaning big and phagein meaning eat.
Macrophages Macrophages are the body's first line of defense and have many roles. A macrophage is the first cell to recognize and engulf foreign substances (antigens). Macrophages break down these substances and present the smaller proteins to the T lymphocytes. (T cells are programmed to recognize, respond to and remember antigens).