Most drugs found to cause nephrotoxicity exert toxic effects by one or more common pathogenic mechanisms. These include altered intraglomerular hemodynamics, tubular cell toxicity, inflammation, crystal nephropathy, rhabdomyolysis, and thrombotic microan-giopathy.
Leclercia adecarboxylata is an opportunistic human pathogen that phenotypically resembles Escherichia coli. The natural susceptibilities of 101 Leclercia strains to 70 antimicrobial agents were investigated. MICs were determined with a microdilution procedure in cation-adjusted MuellerâHinton broth (all strains) and IsoSensitest broth (some strains).
Etymology: L, arachos, a legume. a long-chain fatty acid that is a component of lecithin and a basic material in the biosynthesis of some prostaglandins. In mammals, arachidonic acid is synthesized from linoleic acid.Biochemistry. A polyunsaturated omega-6 fatty acid, which is an essential dietary component for mammals and the precursor for biosynthesis of prostaglandins, thromboxanes and hydroxy-eicosatetraenoic acid derivatives (e.g., leukotrienes). long-chain fatty acid that is a component of lecithin and a basic material in the biosynthesis of some prostaglandins. In mammals, arachidonic acid is synthesized from linoleic acid.