A hole or rupture in the eardrum, a thin membrane that separates the ear canal and the middle ear, is called a perforated eardrum. The medical term for eardrum is tympanic membrane.n this case,there may be infected or bloody drainage from the ear. Infections can cause a hole in the eardrum as a side effect of otitis media. Symptoms of acuteotitis media (middle ear fluid with signs of infection) include a senese of fullness in the ear, some hearing loss, pain, and fever.
Letâs start with what is the meaning of sensitivity and specificity: Sensitivity means that: how much the test can detect the positive cases. Specificity means that: how much the test can detect the negative cases.
Specificity is a property of the enzyme and describes how restrictive the enzyme is in its choice of substrate; a completely specific enzyme would have only one substrate. The specificity of the serine proteases is usually not very high since they have similar active sites and act through the same proteolytic mechanism.