This alters the concentration of carbon dioxide in the blood, shifting the above reaction according to Le Chatelier's principle, which in turn alters the pH. The basic reaction governed by this principle is as follows: H2O + CO2 <--> H2CO3 <--> H+ + CO3-.
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A fashion designer designs clothes, basically. Sometimes they combine different styles together, and sometimes they make up entirely new stuff. They also just add accessories to stuff, like jeans for example, so that it would look better. They find new ways to attract customers to buy there stuff.