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Pseudogout is caused by the formation of calcium pyrophosphate crystals in the synovial fluid in the joints. Crystals can also deposit in the cartilage, where they can cause damage.seudogout most often affects the knees, but also affects ankles, wrists, and elbows. General symptoms may include: 1  periodic episodes of joint pain. 2  swelling of the affected joint.
Pseudogout, also known as calcium pyrophosphate deposition (CPPD) disease, is a type of arthritis that causes spontaneous, painful swelling in your joints. This condition most commonly affects the knees, but it can also affect the ankles, elbows, and wrists.