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1 Cystic fibrosis primarily affects the lungs and digestive system. 2  It leads to the production of mucus that is much thicker and more sticky than usual. 3  Cystic fibrosis is a hereditary condition, caused by a defective gene. 4  The cystic fibrosis gene must be present in both parents for a child to have the condition.
Back to Top Causes. Cystic fibrosis (CF) is caused by a defective gene which causes the body to produce abnormally thick and sticky fluid, called mucus. This mucus builds up in the breathing passages of the lungs and in the pancreas, the organ that helps to break down and absorb food.ystic fibrosis is a disease passed down through families that causes thick, sticky mucus to build up in the lungs, digestive tract, and other areas of the body. It is one of the most common chronic lung diseases in children and young adults. It is a life-threatening disorder.