Thrombocytosis is defined as a platelet count above the upper limit of the normal range (450 x 10 9 /L in adults). This article aims to outline diagnosis, investigation and management of patients with thrombocytosis and to highlight possible complications.
  Dr Edward Jenner discovered the vaccine in 1796 and published his findings in 1798. Edward Jenner invented the vaccine for small pox in 1798.He  prepared the vaccine f â¦ rom the cow pox virus. His discovery could  save more lives than any other medical discovery. Dr Edward Jenner discovered the vaccine in 1796 and published his findings in 1798. Edward Jenner invented the vaccine for small pox in 1798. He  prepared the vaccine f â¦ rom the cow pox virus.
This gave the susceptible person a cowpox infection (which was usually mild) and conveyed protection from smallpox. After a time, a virus similar to cowpox, called vaccinia, was substituted in the vaccine. The last naturally occurring case of smallpox was in Somalia in 1977. In 1980, the World Health Organization (WHO) certified that the world was finally free of smallpox. Thus, smallpox was the first disease to be entirely eradicated.