Dimetapp Paediatric Elixir is contra-indicated in patients sensitive to any of the ingredients and in infants or neonates. It should not be given to patients whose sensitivity to small doses of sympathomimetic substances is manifested by sleeplessness, dizziness, light headaches, weakness, tremulousness or cardiac arrhythmia.
In fact, worrying (or anxiety) can stimulate the release of epinephrine into your system, whereby it will bind with your beta-adrenergic receptors in your liver, causing your blood vessels to constrict and your blood pressure to rise, along with your heart rate (pulse).
Adrenaline is the original name for what we now call epinephrine. Stimulation of the adrenal medulla by the sympathetic nervous system causes the secretion of both epinephrine (E) (80%) and norepinephrine (NE)(20%) into circulation. Epinephrine is a hormone; norepinephrine is both a hormone and a neurotransmitter.lpha 2 Receptors. Alpha 2 receptors are located on secretory terminals of some postsynaptic adrenergic neurons. When these terminals secrete norepinephrine the neurotransmitter binds with these receptors as well as with adrenergic receptors on the other side of the synapse.