Abby Jackson Â· Business Insider 01 Sep 2017. South Africa just saw its credit rating downgraded after two of the three major ratings agencies issued depressing assessments of the state of the countryâs economy.
Mastocytosis (say mass-toe-sigh-toe-sis) is the abnormal growth of mast cells in the body. Mast cells are part of the immune system, which helps protect your body against infection. The most common form of mastocytosis is when mast cells accumulate on the skin, causing reddish-brown spots or bumps.In rare cases, mastocytosis can affect other parts of the body, such as the stomach, the intestines and the bone marrow. Mastocytosis can occur in people of any age.he most common form of mastocytosis is when mast cells accumulate on the skin, causing reddish-brown spots or bumps. In rare cases, mastocytosis can affect other parts of the body, such as the stomach, the intestines and the bone marrow. Mastocytosis can occur in people of any age.
The presence of too many mast cells, or mastocytosis, can occur in two formsâcutaneous and systemic. The most common cutaneous (skin) form is also called urticaria pigmentosa, which occurs when mast cells infiltrate the skin.Systemic mastocytosis is caused by mast cells accumulating in the tissues and can affect organs such as the liver, spleen, bone marrow, and small intestine.Researchers first described urticaria pigmentosa in 1869. Systemic mastocytosis was first reported in the scientific literature in 1949.ystemic mastocytosis is caused by mast cells accumulating in the tissues and can affect organs such as the liver, spleen, bone marrow, and small intestine. Researchers first described urticaria pigmentosa in 1869. Systemic mastocytosis was first reported in the scientific literature in 1949.