This alters the concentration of carbon dioxide in the blood, shifting the above reaction according to Le Chatelier's principle, which in turn alters the pH. The basic reaction governed by this principle is as follows: H2O + CO2 <--> H2CO3 <--> H+ + CO3-.
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Taguchi Orthogonal Array Designs. Taguchi Orthogonal Array (OA) design is a type of general fractional factorial design. It is a highly fractional orthogonal design that is based on a design matrix proposed by Dr. Genichi Taguchi and allows you to consider a selected subset of combinations of multiple factors at multiple levels.