This alters the concentration of carbon dioxide in the blood, shifting the above reaction according to Le Chatelier's principle, which in turn alters the pH. The basic reaction governed by this principle is as follows: H2O + CO2 <--> H2CO3 <--> H+ + CO3-.
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A jewelry designer or jewellery designer (see American and British English spelling differences) is a person who renders original jewelry creations and usually constructs them as well.