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Medical Definition of nitro. : containing or being the monovalent group NO2 united through nitrogen.
Advertisement-Continue Reading Below. Turns out, Kickshaw was on to the biggest coffee trend of the summer, only without the nitrogen. Whereas draft coffee comes straight from the tap, nitro, as brew geeks call it, is coffee infused with nitrogen. Similar to a soda fountain, nitrogenated coffee is extra smooth and looks a little like a Guinness. Stumptown Coffee, a famed roaster out of Portland, released nitro cold brew in a can in April and has supplied many coffee shops (both its own and others) in New York City with kegs of the stuff.