Dimetapp Paediatric Elixir is contra-indicated in patients sensitive to any of the ingredients and in infants or neonates. It should not be given to patients whose sensitivity to small doses of sympathomimetic substances is manifested by sleeplessness, dizziness, light headaches, weakness, tremulousness or cardiac arrhythmia.
In fact, worrying (or anxiety) can stimulate the release of epinephrine into your system, whereby it will bind with your beta-adrenergic receptors in your liver, causing your blood vessels to constrict and your blood pressure to rise, along with your heart rate (pulse).
Epinephrine acts by binding to a variety of adrenergic receptors. Epinephrine is a nonselective agonist of all adrenergic receptors, including the major subtypes Î± 1, Î± 2, Î² 1, Î² 2, and Î² 3. Epinephrine's binding to these receptors triggers a number of metabolic changes.