Most drugs found to cause nephrotoxicity exert toxic effects by one or more common pathogenic mechanisms. These include altered intraglomerular hemodynamics, tubular cell toxicity, inflammation, crystal nephropathy, rhabdomyolysis, and thrombotic microan-giopathy.
Leclercia adecarboxylata is an opportunistic human pathogen that phenotypically resembles Escherichia coli. The natural susceptibilities of 101 Leclercia strains to 70 antimicrobial agents were investigated. MICs were determined with a microdilution procedure in cation-adjusted MuellerâHinton broth (all strains) and IsoSensitest broth (some strains).
Alcaligenes is a genus of Gram-negative, pathogenic, opportunistic bacteria. Alcaligenes xylosoxidans has been found in the respiratory tracts of cystic fibrosis patients.Because species of this genus are often incorrectly identified, problems linked to cystic fibrosis are difficult to study and rectify. Isolates of this genus have been found in soil or water.lcaligenes xylosoxidans has been found in the respiratory tracts of cystic fibrosis patients. Because species of this genus are often incorrectly identified, problems linked to cystic fibrosis are difficult to study and rectify.