The steady-state plasma concentration that is reached is 4.0 mg/L, so TC = 4.0 mg/L loading dose = 8 mg/hour Vd = loading dose/TC Vd = 8 mg/hour / 4 mg/L = 2 L What is the volume of distribution? CL = kVd t1/2 = 0.7 / k t1/2 = 0.7 Vd/CL Vd = CL * t1/2 / 0.7 Note that Clearance at a steady state can be calculated by: Dose <steady state> = CL * TC, so
As a regulator of sensory information, the thalamus also controls sleep and awake states of consciousness. Function: The thalamus is involved in several functions of the body including: 1  Motor Control. 2  Receives Auditory, Somatosensory and Visual Sensory Signals. 3  Relays Sensory Signals to the Cerebral Cortex.
All sensory inputs to the brain, except that of the sense of smell, are through the thalamus. The hypothalamus is involved with the body's vital drives and activities, such as eating, drinking, temperature regulation, sleep, emotional behavior, and sexual activity. Mapping the Human Brain: Location of the Thalamus The thalamus is an important part of the human brain. 2  It is responsible for sending and receiving signals to and from many different parts of the body back to the brain.