About SLP. Established in 1987, SLP has stood for quality performance enhancements for late-model American Muscle cars from the beginning, and it continues this commitment today.
Mispriming in PBAT libraries causes methylation bias and poor mapping efficiencies. Random priming in PBAT libraries introduces drastic biases in the base composition and methylation levels especially at the 5â² end of all reads. As a result, affected bases should be removed from the libraries before the alignment step.
Mutations occur, quite simply, because it's impossible to achieve 100% accuracy during DNA replication (think of the sheer numbers of base pairs involved) and then not all of the mistakes are detected and then not all of those are correctly repaired.