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The vaccines have been shown to offer 100 percent protection against the development of cervical pre-cancers and genital warts caused by the HPV types in the vaccine, with few or no side effects. The protective effects of the vaccine are expected to last a minimum of 4.5 years after the initial vaccination.
For women, it's best to get three doses of the same vaccine, but if that is not possible, either vaccine can be given. Both vaccines will protect you against HPV for at least five years. It may last much longer, or you may need a booster shot. More studies need to be done to show how long it lasts.