The steady-state plasma concentration that is reached is 4.0 mg/L, so TC = 4.0 mg/L loading dose = 8 mg/hour Vd = loading dose/TC Vd = 8 mg/hour / 4 mg/L = 2 L What is the volume of distribution? CL = kVd t1/2 = 0.7 / k t1/2 = 0.7 Vd/CL Vd = CL * t1/2 / 0.7 Note that Clearance at a steady state can be calculated by: Dose <steady state> = CL * TC, so
As a regulator of sensory information, the thalamus also controls sleep and awake states of consciousness. Function: The thalamus is involved in several functions of the body including: 1  Motor Control. 2  Receives Auditory, Somatosensory and Visual Sensory Signals. 3  Relays Sensory Signals to the Cerebral Cortex.
These roots become nerves that innervate (transmit nerve impulses to) muscles and organs throughout the body. Twelve pairs of cranial nerves transmit from special sensory receptors information on the senses of balance, smell, sight, taste, and hearing.he thalamus is a relay and preprocessing station for the many nerve impulses that pass through it. Impulses carrying similar messages are grouped in the thalamus, then relayed to the appropriate brain areas. The epithalamus is the most dorsal (posterior) portion of the diencephalon.