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The juice contains a number of important digestive enzymes, including trypsin, chymotrypsin, carboxypeptidase, lipase, and amylase. Pancreatic juice is alkaline in nature because of a high concentration of bicarbonate ions; this helps to neutralize the acidic gastric juice from the stomach.
Another enzyme present in the pancreatic juice is cholesterol esterase (EC 3.1.1.13). 1  The enzyme, synthesized and secreted in an active form by the exocrine pancreas, is a lipase with broad specificity, being active on: 2  cholesterol esters, with cholesterol and free fatty acids as reaction products;