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The juice contains a number of important digestive enzymes, including trypsin, chymotrypsin, carboxypeptidase, lipase, and amylase. Pancreatic juice is alkaline in nature because of a high concentration of bicarbonate ions; this helps to neutralize the acidic gastric juice from the stomach.
Pancreatic juice is composed of two secretory products critical to proper digestion: digestive enzymes and bicarbonate. The enzymes are synthesized and secreted from the exocrine acinar cells, whereas bicarbonate is secreted from the epithelial cells lining small pancreatic ducts.. Proteases Digestion of proteins is initiated by pepsin in the stomach, but the bulk of protein digestion is due to the pancreatic proteases.