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However, long-term fatigue and other CFS symptoms can be signs of more serious medical or psychological problems. It is important to rule out other conditions that can cause these symptoms by performing a careful evaluation and laboratory tests. Infectious Mononucleosis and Epstein-Barr Virus. Infectious mononucleosis causes fatigue and swollen glands. It primarily affects adolescents and young adults. Research finds that fatigue may last for a year or more in a small percentage of adolescents who have had mononucleosis. Females and people with more severe fatigue are more likely to develop chronic fatigue syndrome after mononucleosis. Blood tests can detect the Epstein-Barr virus (EBV), which causes mononucleosis. Autoimmune Diseases. Some diseases, including systemic lupus erythematosus, multiple sclerosis, and rheumatoid arthritis are caused by autoimmunity, a condition in which the person's immune system attacks the body's own tissues.
The virus spreads through saliva, which is why it's sometimes called kissing disease. Mono occurs most often in teens and young adults. However, you can get it at any age. Symptoms of mono include. Fever; Sore throat; Swollen lymph glands; Sometimes you may also have a swollen spleen. Serious problems are rare. A blood test can show if you have mono. Most people get better in two to four weeks. However, you may feel tired for a few months afterward. Treatment focuses on helping symptoms and includes medicines for pain and fever, warm salt water gargles and plenty of rest and fluids.