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The vaccines have been shown to offer 100 percent protection against the development of cervical pre-cancers and genital warts caused by the HPV types in the vaccine, with few or no side effects. The protective effects of the vaccine are expected to last a minimum of 4.5 years after the initial vaccination.
American Cancer Society recommendations. To work best, the HPV vaccine should be given before the young person has had any type of sexual contact with another person. 1  Routine HPV vaccination is recommended for girls 11 to 12 years old. 2  Girls as young as age 9 can get HPV vaccination.