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Potential side effects of common diabetes drugs*. 1  Sulfonylureas: low blood sugar, upset stomach, skin rash or itching, weight gain. 2  Biguanides/Metformin: sickness with alcohol, kidney complications, upset stomach, tiredness or dizziness, metal taste. 3  Alpha-glucosidase inhibitors: gas, bloating and diarrhoea.
Liver issues in diabetes are complicated. An article in the journal Clinical Diabetes explained that diabetes can cause liver disease; liver disease can cause diabetes; or both can arise together from other causes. Whichever comes first, the sick liver may produce way too much glucose, enough to overwhelm the bodyâs insulin.