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Depending on the species, the blastopore has been reported to become the mouth (protostomy), the anus (deuterostomy), both mouth and anus (amphistomy), or neither (i.e., the blastopore closes).
The hallmark of gastrulation in some organisms is the formation of the blastopore. The blastopore is the site at which endoderm and/or mesoderm formation begins. The physical forces involved in molding the gastrula are currently being revisited, and much research remains to be done.