About SLP. Established in 1987, SLP has stood for quality performance enhancements for late-model American Muscle cars from the beginning, and it continues this commitment today.
Mispriming in PBAT libraries causes methylation bias and poor mapping efficiencies. Random priming in PBAT libraries introduces drastic biases in the base composition and methylation levels especially at the 5â² end of all reads. As a result, affected bases should be removed from the libraries before the alignment step.
Spontaneous mutations. Spontaneous mutations arise from a variety of sources, including errors in DNA replication, spontaneous lesions, and transposable genetic elements. The first two are considered in this section; the third is examined in Chapter 20. Errors in DNA replication.