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Medications to treat gout attacks. Nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs include over-the-counter options such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve, others), as well as more-powerful prescription NSAIDs such as indomethacin (Indocin) or celecoxib (Celebrex).
Oral steroid medications or injections in the affected joint may be helpful in reducing pain and inflammation in severe attacks or chronic cases. However, steroids can have undesirable side effects and must always be given by a doctor. Another treatment for acute gout is colchicine.