The so-called classic catabolic hormones known since the early 20th century are cortisol, glucagon, and adrenaline (and other catecholamines). In recent decades, many more hormones with at least some catabolic effects have been discovered, including cytokines, orexin (also known as hypocretin), and melatonin.
The Medici family, also known as the House of Medici, first attained wealth and political power in Florence in the 13th century through its success in commerce and banking.
The city of Florence is really where the Renaissance began. In those days, Italy was not one single country. It was lots of little states, all governed in different ways and all fighting or making allies with each other all the time.