Abby Jackson Â· Business Insider 01 Sep 2017. South Africa just saw its credit rating downgraded after two of the three major ratings agencies issued depressing assessments of the state of the countryâs economy.
Mastocytosis (say âmas-toe-sigh-toe-sisâ) is a rare disease of the skin (the most common form), or of other parts of the body (very rare), like the stomach, the intestines and the bone marrow.It's caused by having too many mast cells. Mast cells are a kind of blood cell.Mastocytosis can occur at any age.astocytosis (say âmas-toe-sigh-toe-sisâ) is a rare disease of the skin (the most common form), or of other parts of the body (very rare), like the stomach, the intestines and the bone marrow.
releasing chemical âalarmsâ such as histamine and cytokines. The presence of too many mast cells, or mastocytosis, can occur in two formsâcutaneous and sysÂ­. temic. The most common cutaneous (skin) form is also called urticaria pigmentosa, which occurs. when mast cells infiltrate the skin.Systemic mastocytosis is caused by mast cells accumulating in the. tissues and can affect organs such as the liver, spleen, bone marrow, and small intestine.such as the liver and spleen), and the linings of the lung, stomach, and intestine. The presence of too many mast cells, or mastocytosis, can occur in two formsâcutaneous and sysÂ­. temic. The most common cutaneous (skin) form is also called urticaria pigmentosa, which occurs. when mast cells infiltrate the skin.