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The vaccines have been shown to offer 100 percent protection against the development of cervical pre-cancers and genital warts caused by the HPV types in the vaccine, with few or no side effects. The protective effects of the vaccine are expected to last a minimum of 4.5 years after the initial vaccination.
The primary target group in most of the countries recommending HPV vaccination is young adolescent girls, aged 9-14. For both HPV vaccines, the vaccination schedule depends on the age of the vaccine recipient. Females <15 years at the time of first dose: a 2-dose schedule (0, 6 months) is recommended. If the interval between doses is shorter than 5 months, then a third dose should be given at least 6 months after the first dose.