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Expectorants are medications that break apart mucus and make it easier to cough up and expel from your body. There are many over-the-counter expectorants available at drug stores, but you can go to your doctor for a prescription as well.
Expectorants are the most common medication used to reduce the amount of mucus in the chest. These medications work by thinning mucus in the chest and providing lubrication so coughing is more productive, according to the University of Iowa. The most common expectorant drug is guaifenisin.