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How soon before sexual intercourse should I take Viagra? A good rule of thumb is to take Viagra 45 minutes or an hour before you expect to have sex. After a few hours, its effects lessen considerably, so timing is of a concern. Unfortunately, there's no one-size-fits-all answer to this question.
Cialis tends to take effect more quickly than other ED drugs, with onset of effectiveness within 30 minutes typically. The recommendation is to take Cialis 30 minutes prior to sexual activity, while with Viagra and Levitra, users are instructed to take the drug 60 minutes before sexual activity. Generally, the effects of Cialis last 24 to 36 hours after taking it.