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Medications to treat gout attacks. Nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs include over-the-counter options such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve, others), as well as more-powerful prescription NSAIDs such as indomethacin (Indocin) or celecoxib (Celebrex).
10 Gout Treatments. Treatment for gout focuses on pain relief to better cope with a gout attack. There are a number of natural and medicinal options available that can also be enhanced by lifestyle changes to prevent future attacks. Most mild to moderate gout symptoms can be managed by resting the joints.