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Macrophages are important cells of the immune system that are formed in response to an infection or accumulating damaged or dead cells. Macrophages are large, specialized cells that recognize, engulf and destroy target cells. The term macrophage is formed by the combination of the Greek terms makro meaning big and phagein meaning eat.
Macrophages The macrophage is one of the most important cells of the immune system. For many years it has been known as the main phagocyte of the immune system. Macrophages eat and destroy pathogens, such as bacteria, viruses and fungi, thus they are a critical part of the body's defense against microorganisms.acrophages are produced in the bone marrow, where red blood cells, platelets and granulocytes are made. In the bone marrow, macrophage precursor cells are called promonocytes. Promonocytes eventually mature and migrate into the blood, where they are called monocytes. Monocytes are only found in the blood.