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The following adverse effects have been attributed to the consumption of food additives: eczema, urticaria, angioedema, exfoliative dermatitis, irritable bowel syndrome, nausea, vomiting, diarrhoea, rhinitis, bronchospasm, migraine, anaphylaxis, hyperactivity and other behavioural disorders.
Answers from John E. Huxsahl, M.D. Food additives include artificial colors, artificial sweeteners and preservatives. There's no solid evidence that food additives cause attention-deficit/hyperactivity disorder (ADHD). However, the topic of food additives and their possible effects is controversial. Some studies indicate that certain food colorings and preservatives may increase hyperactive behavior in some children.