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Common glucocorticoids include prednisone, dexamethasone, and hydrocortisone. While glucocorticoids are widely used as drugs to treat various inflammatory conditions, prolonged glucocorticoid use may have adverse side effects such as immunosuppression, fluid shifts, brain changes, and psychological changes.
Clinical pharmacology Any of the steroids elaborated by the adrenal cortexâexcluding the sex hormones of adrenal origin in response to the release of ACTH by the pituitary gland, to any of their synthetic equivalents or to angiotensin II; corticosteroids are used to manage arthropathies, inflammation, CA.he corticosteroids synthesized by the adrenal glands include the glucocorticoids and the mineralocorticoids. The principal glucocorticoids are cortisol and corticosterone. The only physiologically important mineralocorticoid in humans is aldosterone. These hormones may be manufactured and administered exogenously.