The steady-state plasma concentration that is reached is 4.0 mg/L, so TC = 4.0 mg/L loading dose = 8 mg/hour Vd = loading dose/TC Vd = 8 mg/hour / 4 mg/L = 2 L What is the volume of distribution? CL = kVd t1/2 = 0.7 / k t1/2 = 0.7 Vd/CL Vd = CL * t1/2 / 0.7 Note that Clearance at a steady state can be calculated by: Dose <steady state> = CL * TC, so
As a regulator of sensory information, the thalamus also controls sleep and awake states of consciousness. Function: The thalamus is involved in several functions of the body including: 1  Motor Control. 2  Receives Auditory, Somatosensory and Visual Sensory Signals. 3  Relays Sensory Signals to the Cerebral Cortex.
Thalamus/thalamus. Thalamus is a large elliptical grey mass of nuclei positioned in each hemisphere on each side of the third ventricle interconnected by the interthalamic adhesion/ adhesio interthalamica. Myelinated fiber bundles emerge from the lateral surface of thalamus and terminate in the cerebral cortex.halamus is the principle relay station for sensory impulses from the spinal cord, brainstem, cerebellum and other parts of the cerebrum to the cortex. The anterior choroidal artery provides blood supply of the thalamus.