Thrombocytosis is defined as a platelet count above the upper limit of the normal range (450 x 10 9 /L in adults). This article aims to outline diagnosis, investigation and management of patients with thrombocytosis and to highlight possible complications.
  Dr Edward Jenner discovered the vaccine in 1796 and published his findings in 1798. Edward Jenner invented the vaccine for small pox in 1798.He  prepared the vaccine f â¦ rom the cow pox virus. His discovery could  save more lives than any other medical discovery. Dr Edward Jenner discovered the vaccine in 1796 and published his findings in 1798. Edward Jenner invented the vaccine for small pox in 1798. He  prepared the vaccine f â¦ rom the cow pox virus.
Although the first vaccine against smallpox was developed in 1796, greater than 100 years later its use had not been widespread enough to fully control the disease (4). Four other vaccines -- against rabies, typhoid, cholera, and plague -- had been developed late in the 19th century but were not used widely by 1900.lthough the first vaccine against smallpox was developed in 1796, greater than 100 years later its use had not been widespread enough to fully control the disease (4). Four other vaccines -- against rabies, typhoid, cholera, and plague -- had been developed late in the 19th century but were not used widely by 1900.