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1 Cystic fibrosis primarily affects the lungs and digestive system. 2  It leads to the production of mucus that is much thicker and more sticky than usual. 3  Cystic fibrosis is a hereditary condition, caused by a defective gene. 4  The cystic fibrosis gene must be present in both parents for a child to have the condition.
Best Answer: People with cystic fibrosis inherit a defective gene on chromosome 7 called CFTR (cystic fibrosis transmembrane conductance regulator).ssociated Disorders: Defective versions of this protein, caused by CFTR gene mutations, can lead to the development of cystic fibrosis (CF) and congenital bilateral aplasia of the vas deferens (CBAVD). You can click on this link to see a diagram of the gene: http://www.ornl.gov/sci/techresources/Hu...