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Interactions With Medications. Even though vitamin B-12 is safe if you take too much, it can interact negatively with certain medications. Chloramphenicol, a type of antibiotic, affects how your body responds to B-12.Even though you're taking a large dose of B-12, the medication limits the vitamin's function.ost vitamins and minerals can be toxic if you take too much. However, vitamin B-12 is a little different. Your system only absorbs a small amount at a time and gets rid of what it doesn't need, which means it's generally safe, even if you take too much.
â¢ Low levels of vitamin B 12 can cause pernicious anemia. Vegetarians who eat no animal products and the elderly who absorb less vitamin B 12 are most at risk. â¢ Vitamin B12 is found only in animal foods and fortified foods.People who avoid all animal products should look for meat alternatives, such as soy products fortified with vitamin B 12.â¢ Ten to thirty percent of older people may not absorb vitamin B 12 well. Vitamin B12 is found only in animal foods and fortified foods. People who avoid all animal products should look for meat alternatives, such as soy products fortified with vitamin B 12. â¢ Ten to thirty percent of older people may not absorb vitamin B 12 well.