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All blood donations are processed and available for use usually within 24 hours. Whole blood is processed into components (red blood cells, platelets, plasma). After processing, the red blood cells can be stored for 42 days.
Donated plasma is replaced after 2â3 days. Red blood cells are replaced by bone marrow into the circulatory system at a slower rate, on average 36 days in healthy adult males. In one study, the range was 20 to 59 days for recovery. These replacement rates are the basis of how frequently a donor can donate blood.