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1 Replicate (biology), the exact copy resulting from self-replication of genetic material, a cell, or an organism.  Replicate (statistics), a fully repeated experiment or set of test conditions.
replication. 1  1. a turning back of a part so as to form a duplication. 2  2. repetition of an experiment to ensure accuracy. 3  3. the process of duplicating or reproducing, as replication of an exact copy of a polynucleotide strand of DNA or RNA.