In accordance with FAR 52.232-22 paragraph (f)(1) âThe Government is not obligated to reimburse the Contractor for costs incurred in excess of the total amount allotted by the Government to this contract.â FYXX funding has not yet been received.
Myofibrils account for roughly 80% of cellular volume, and are the contractile elements of the muscle cell. Myofibrils consist of repeating units called sarcomeres (the contractile unit of the myofibril), which have overlapping myofilaments connected to Z discs at either end of the sarcomere.
Actin and myosin are contractile proteins in muscle tissue. Muscle tissue can be categorized into skeletal muscle tissue, smooth muscle tissue, and cardiac muscle tissue. Skeletal muscle fibers are cylindrical, multinucleated, striated, and under voluntary control. Smooth muscle cells are spindle shaped, have a single, centrally located nucleus, and lack striations. They are called involuntary muscles. Cardiac muscle has branching fibers, one nucleus per cell, striations, and intercalated disks. Its contraction is not under voluntary control.