Acquired. 1  Liver dysfunction or disease â almost all coagulation factors are produced in the liver; liver disease may result in decreased production of factors. 2  Vitamin K deficiency â the synthesis of several coagulation factors (II, VII, IX, X) requires vitamin K. bleeding disorder may be due to a lack of one or more clotting factors or the result of factors that do not function properly. Deficiency or dysfunction of coagulation factors may have genetic causes (inherited) or may be the result of another disease or condition. The following are a few examples: Inherited.
messenger RNA. noun. : an RNA produced by transcription that carries the code for a particular protein from the nuclear DNA to a ribosome in the cytoplasm and acts as a template for the formation of that proteinâcalled also mRNA; compare transfer rna.
Translating the code into an actual protein chain is complicated by the fact that individual amino acids won't interact with the messenger RNA chain. The amino acids have to be carried to the messenger RNA by another type of RNA known as transfer RNA-abbreviated to tRNA (as opposed to mRNA for messenger RNA). All of this is controlled by a ribosome-a hugely complicated structure involving protein molecules and yet another form of RNA (ribosomal RNA or rRNA).