adjective. 1  regardless of sin reparar en; buy it regardless of the cost cÃ³mpralo, cueste lo que cueste; they shot them all regardless of rank los fusilaron a todos sin miramientos a su graduaciÃ³n; we did it regardless of the consequences lo hicimos sin tener en cuenta las consecuencias.
Yes, their are two active ingredients in tramacet. Tramadol hydrochloride and paracetamol. Tramadol hydrochloride is an opioid and is closely related to morphine. It is actually synthetic form of morphine.
The two-step strategy considers the use of low doses of strong opioid for the moderate pain in contrast to the three-step conventional ladder that recommends the use of codeine or tramadol (weak opioid) for the treatment of moderate pain.