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During the digestive period, intestinal phase signals stimulate the release of bile into the small intestine. Fatty acids in the lumen of the duodenum stimulate endocrine cells to release the hormone cholecystokinin (CCK). CCK stimulates contractions in the smooth muscle of the gallbladder. Views.
Bile enters the duodenum when dietary fats are present. If any bile remains after the fat has been digested, it is taken back up by the gallbladder. The gallbladder is a small sac-shaped organ that stores and concentrates bile.The common bile duct is a common duct that carries bile from the liver and the gallbladder to the duodenum. If this duct is blocked, it can cause the yellowish-colored bile to back up and enter the bloodstream.This can lead to a yellowing of the skin and the whites of the eyes, known as jaundice.ile is produced by the liver and stored in the gallbladder. In this lesson, you will learn about bile and its role in the breakdown of dietary fats. You will also learn how the hormones secretin and cholecystokinin help regulate these organs.