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Patients with cardiomyopathy, a stiffening and thickening of the heart muscle that weakens it, may develop an enlarged heart as it labors to pump an adequate supply of blood to the body. Coronary artery disease, in which plaque in the arteries interferes with the flow of blood, can cause the heart to enlarge.
Causes of heart palpitations. Heart palpitations are frequently caused by stress or anxiety. In addition to making you feel terrible emotionally, stress can have a physical effect on your body. As a result, stress can cause the nerve endings that control your heart to fire more frequently or irregularly. Anxiety and panic attacks can also trigger palpitations by elevating adrenaline levels. Food and drink can cause heart palpitations. Caffeine, nicotine, and alcohol can all affect your heart rate and may also increase the likelihood of irregular heartbeats. Some medications can cause heart palpitations. These include asthma inhalers, over the counter medications such as pseudoephedrine, and thyroid medications.