The purpose of this study is to better understand the genetic factors related to the Chiari I malformation. In people with this abnormality, the lower part of the skull is smaller than normal.andidates for this study are: 1) Patients with Chiari I malformation who also have a family member with the abnormality or a family member with syringomyelia (a cyst in the spinal cord that is often associated with the Chiari I malformation).
A hemoglobin electrophoresis test is a blood test used to measure and identify the different types of hemoglobin in your bloodstream. Hemoglobin is the protein inside red blood cells that is responsible for transporting oxygen throughout your circulatory system to your tissues and organs.he types of hemoglobin include: 1  hemoglobin F: This type is found in growing fetuses and newborns. 2  hemoglobin A: This is the most common type of hemoglobin found in healthy children and adults. 3  hemoglobin C, D, E, M, and S: These (and many other, rarer variations) are types of abnormal hemoglobin.
Methods for hemoglobinometry can be grouped into 4 main classes depending on the basic technique employed with variants within each class: 1. Colorimetric Methods. 2. Gasometric Methods. 3. Specific Gravity Methods. 4. Chemical Methods. The method of choice for hemoglobin determination is the cyanmethemoglobin method (This is a type of colorimetric method). The principle of this method is that when blood is mixed with a solution containing potassium ferricyanide and potassium cyanide, the potassium ferricyanide oxidizes iron to form methemoglobin.