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Certain medications may also lead to a low white blood cell count because they can destroy white blood cells or damage the bone marrow. For example, taking antibiotics may sometimes cause an abnormal drop in neutrophils, a condition known as neutropenia.
The human immunodeficiency virus (HIV), tuberculosis, viral hepatitis and typhoid fever are examples of infections that lower the lymphocyte count. A low lymphocyte or white blood cell count increases a person's risk of infection. The NHLBI advises people who have this condition to stay away from people who are sick, avoid foods that potentially are contaminated with bacteria and practice good oral hygiene. Regular hand-washing is important in reducing risk of infection, as well.