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Insulin and glucagon are hormones that work to regulate the level of sugar (glucose) in the body to keep it within a healthy range. Unlike the acinar cells, the islets of Langerhans do not have ducts and secrete insulin and glucagon directly into the bloodstream. Depending on what youâve eaten, how much exercise your muscles are doing, and how active your body cells are, the amount of glucose in your bloodstream and cells varies.
A counterregulatory hormone that works against the action of insulin. Most people with diabetes know that insulin is secreted by the beta cells of the pancreas. What many donât know is that other cells in the pancreas called alpha cells secrete the hormone glucagon. Glucagon is one of the counterregulatory hormones that helps the body regulate blood glucose levels. In people who donât have diabetes, when blood glucose levels fall, the beta cells secrete less insulin. In addition, the alpha cells secrete more glucagon.