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All parts are affected in some manner, since it is a disease that affects the brain. It is a disease of nervous system. So it affects the parts wherever nerves are and nerves are about everywhere in body. Huntington's is a neurological disease that affects the brain.
Lupus is an autoimmune disease that can affect almost any part of your body, including your joints, skin, kidneys, heart, lungs, or blood. Lupus can also affect the nervous system and brain. There are several terms doctors use to describe this: neuropsychiatric lupus (NPSLE), neurocognitive dysfunction, or central nervous system lupus (CNS lupus). The nervous system has three parts, any of which may be affected by lupus. 1  The central nervous system (CNS)âThe brain and spinal cord.