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Patients with cardiomyopathy, a stiffening and thickening of the heart muscle that weakens it, may develop an enlarged heart as it labors to pump an adequate supply of blood to the body. Coronary artery disease, in which plaque in the arteries interferes with the flow of blood, can cause the heart to enlarge.
Get the facts on the causes, risk factors, and symptoms of an enlarged heart (cardiomegaly). An enlarged heart, or cardiomegaly, is the term used to describe a heart that has a thickened wall or dilated chambers.Having a heart that is enlarged is not a disease but a symptom of an underlying medical condition.When there is an increase workload on the heart due to disease, viruses, inflammation, or high blood pressure the heart must work harder to maintain normal function, which can result in an enlarged heart.auses of an Enlarged Heart. An enlarged heart can result from a variety of different causes. Hypertension (high blood pressure) and coronary artery disease are the most common underlying problems that result in heart enlargement.