In bacteria, transcription begins with the binding of RNA polymerase to the promoter in DNA. RNA polymerase is a core enzyme consisting of five subunits: 2 Î± subunits, 1 Î² subunit, 1 Î²' subunit, and 1 Ï subunit.
Untreated gout can cause a risk for diabetes and heart disease. Chronic gout can also cause kidney stones. Gout is caused by a buildup of uric acid in the blood. It cristalizes in the joints, with the big toe being the location in half of the cases. This is called podagra.
If left untreated, gout can lead to serious health issues. People who have chronic kidney disease (CKD) are at increased risk for gout and often are unaware of this risk. If left untreated, gout can lead to serious health issues. People who have chronic kidney disease (CKD) are at increased risk for gout and often are unaware of this risk.