Acetanilide: Acetanilide,, synthetic organic compound introduced in therapy in 1886 as a fever-reducing drug. Its effectiveness in relieving pain was discovered soon thereafter, and it
MidÂ·west. A region of the north-central United States around the Great Lakes and the upper Mississippi Valley. It is generally considered to include Ohio, Indiana, Illinois, Michigan, Wisconsin, Minnesota, Iowa, Missouri, Kansas, and Nebraska. The area is known for its rich farmlands and highly industrialized centers.
In the Ranally city rating system, Chicago is ranked 1-AAA, which is the highest ranking of any Midwest city. Cleveland, Detroit, Minneapolis, and St. Louis are ranked 1-AA. Cincinnati, Columbus, Indianapolis, Kansas City, and Milwaukee are ranked 1-A. For the definition of the Midwest, I use the U.S. Census Bureau's official definition of the region, which is the 12-state region stretching from Ohio on the east to Kansas, Nebraska, South Dakota, and North Dakota on the west.