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All blood donations are processed and available for use usually within 24 hours. Whole blood is processed into components (red blood cells, platelets, plasma). After processing, the red blood cells can be stored for 42 days.
How long after blood donation are you low on blood? Following a 500 ml (+/- 50 ml) whole blood donation, lost volume is replaced within 2-4 hours as fluid is recruited from the interstitial tissue space. Red cell mass is replac â¦ ed within 2-4 weeks by the bone marrow, if adequate iron stores are present.