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Born Martha Wayles in 1748, Martha Jefferson was the first and only wife of President Thomas Jefferson. She, however, never got to fulfill any duties as first ladyâshe died years before he was elected president.
He had two daughters that lived to adulthood: Martha Patsy Jefferson Randolph and Mary Polly Jefferson Eppes. He also had three other daughters and a son who all died â¦ before they were three. The son was not named, two of the daughters were named Lucy and one Jane. There is DNA evidence that he or his nephew fathered a child with a slave, Sally Hemings. 25 people found this useful.