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Anaphylactic reactions are excluded by the presence of red plasma or urine, discordant pretransfusion and posttransfusion ABO blood types, or a positive direct antiglobulin (Coombs) test result. Demonstration of anti-IgA in a pretransfusion sample of the recipient's serum or plasma establishes the diagnosis.
Before you get a blood transfusion, your blood is tested to find out your blood type. And the blood you will get in the transfusion is tested to make sure it matches your blood. You may have a mild allergic reaction even if you get the correct blood type. Signs of a reaction include: 1  A fever.2  Hives.3  Shortness of breath. 4  Pain. 5  A fast heart rate.nd the blood you will get in the transfusion is tested to make sure it matches your blood. You may have a mild allergic reaction even if you get the correct blood type. Signs of a reaction include: 1  A fever. 2  Hives. 3  Shortness of breath.