This factor works with calcium and Christmas factor to enable activation of Stuart factor. It is solely activated by thrombin that originates from platelets and endothelium lining of blood vessels. It is intrinsic in pathway. Anti-hemophilic factor A and globulin are its other designations.
Shock (circulatory) Circulatory shock, commonly known as shock, is a life-threatening medical condition of low blood perfusion to tissues resulting in cellular injury and inadequate tissue function.
Shock is a defence response. In medical terms, shock is the bodyâs response to a sudden drop in blood pressure. At first, the body responds to this life-threatening situation by constricting (narrowing) blood vessels in the extremities (hands and feet).