Video: Nondisjunction and Aneuploidy. Learn why proper chromosome segregation is essential during meiosis. We'll see how having an extra chromosome can lead to Down Syndrome and also examine the consequences of having too few chromosomes. Disruptions to the delicate balance of cell division can have far-reaching effects. Biology 101: Intro to Biology / Science Courses.
The rights for the first four novels in the series were sold to Warner Bros. for Â£1,000,000 by J.K. Rowling. After the release of the fourth book in July 2000, the first film, Harry Potter and the Philosopher's Stone, was released on 16 November 2001.
The first movie in the series, Harry Potter and the Sorcererâs Stone, opened in America on November 16, 2001. Directed by Chris Columbus (Home Alone, Mrs. Doubtfire), the film starred British actor Daniel Radcliffe as Harry, Rupert Grint as Ron and Emma Watson in the role of Hermione.