A 2014 image of product shortages in Venezuela. In economics, a shortage or excess demand is a situation in which the demand for a product or service exceeds its supply in a market. It is the opposite of an excess supply (surplus).
Addisonâs disease is a severe or total deficiency of the hormones made in the adrenal cortex, caused by its destruction.There are normally two adrenal glands, located one above each kidney. The adrenal glands are really two endocrine (ductless or hormone producing) glands in one.ortisol production is regulated by another hormone, adrenocorticotrophic hormone (ACTH), made in the pituitary gland which is located just below the brain. Classical Addisonâs disease results from a loss of both cortisol and aldosterone secretion due to the near total or total destruction of both adrenal glands.
Addisonâs disease, the common term for primary adrenal insufficiency, occurs when the adrenal glands are damaged and cannot produce enough of the adrenal hormone cortisol. The adrenal hormone aldosterone may also be lacking. Addisonâs disease affects 110 to 144 of every 1 million people in developed countries.1.