Acetanilide: Acetanilide,, synthetic organic compound introduced in therapy in 1886 as a fever-reducing drug. Its effectiveness in relieving pain was discovered soon thereafter, and it
MidÂ·west. A region of the north-central United States around the Great Lakes and the upper Mississippi Valley. It is generally considered to include Ohio, Indiana, Illinois, Michigan, Wisconsin, Minnesota, Iowa, Missouri, Kansas, and Nebraska. The area is known for its rich farmlands and highly industrialized centers.
The division contains five states: Illinois, Indiana, Michigan, Ohio, and Wisconsin. It is one of two divisions used to categorize the region of the U.S. generally called the  Midwest  or  Great Lakes region ; the other such division is the West North Central States (The Great Plains States).