CNS depression is generally caused by the use of depressant drugs such as alcohol, opioids, barbiturates, benzodiazepines, general anesthetics, and anticonvulsants such as pregabalin used to treat epilepsy.n a study comparing the central nervous depression due to supra-therapeutic doses of Triazolam (Benzodiazepine), Pentobarbital (Barbiturate) and GHB it appeared as if GHB had the strongest dose-effect function.
If there is one landmark that says Hollywood to the world - literally! - it is the famous Hollywood Sign, perched high atop Mount Lee, the tallest peak in L.A. The Sign measures 450 feet long, its mammoth letters are 45 feet high, and it's visible from all parts of Hollywood.
Answers. 1  The change took place in 1949. The HOLLYWOOD sign is a famous landmark in Los Angeles, California that dates back to 1923, with periodic restoration since then. The sign originally read HOLLYWOODLAND, and its purpose was to advertise a new housing development in the hills above the Hollywood district of Los Angeles. The sign's letters were 30 feet (9 m) wide and 50 feet (15 m) high, and were originally studded with light bulbs. The sign was officially dedicated on July 13, 1923.