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Anaphylactic reactions are excluded by the presence of red plasma or urine, discordant pretransfusion and posttransfusion ABO blood types, or a positive direct antiglobulin (Coombs) test result. Demonstration of anti-IgA in a pretransfusion sample of the recipient's serum or plasma establishes the diagnosis.
These risks are often associated with urinary catheterization, or the use of a catheter to withdraw urine from the bladder. Problematic issues may also arise during some blood transfusions. When selecting a catheter for a blood transfusion, the primary consideration should be the size of the patient's vein.