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Certain medications may also lead to a low white blood cell count because they can destroy white blood cells or damage the bone marrow. For example, taking antibiotics may sometimes cause an abnormal drop in neutrophils, a condition known as neutropenia.
Because a low white blood count can be life threatening, itâs a good idea to familiarize yourself with the symptoms and terminology. When you get your blood work, the lab will be looking for: 1  Leukopenia â A decrease in the total number of white blood cells, which can lead to a lowered white blood cell count. Leukopenia â A decrease in the total number of white blood cells, which can lead to a lowered white blood cell count. 2  Neutropenia â A decrease in the number of neutrophils, also creating a lower WBC. 3  Granulocytopenia â Another term that may be used for Neutropenia.