Amikacin was patented in 1971 and came into commercial use in 1976. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is 13.80 to 130.50 USD for a month.
olfactory. pertaining to smell. olfactory nerve the first cranial nerve; it is purely sensory and is concerned with the sense of smell. The nerve cell bodies are situated in the olfactory area of the mucous membrane of the nose.lfactory system. includes the olfactory part of the nasal mucosa, the olfactory nerves and the olfactory bulbs of the cerebrum. olfactory tract. a band of white nerve fibers visible on the ventral surface of the brain running caudally from the olfactory bulbs.
The olfactory epithelium is a specialized epithelial tissue inside the nasal cavity that is involved in smell. In humans, it measures about 3 square centimeters (on each side) and lies on the roof of the nasal cavity about 7 cm above and behind the nostrils.he olfactory nerves go through the cribriform plate and terminate on the dendrites of the mitral cells located in the glomeruli of the olfactory bulb. The apical poles of these neurons are covered with non-motile cilia, with the plasma membrane containing odorant-binding proteins acting as olfactory receptors.