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Anaphylactic reactions are excluded by the presence of red plasma or urine, discordant pretransfusion and posttransfusion ABO blood types, or a positive direct antiglobulin (Coombs) test result. Demonstration of anti-IgA in a pretransfusion sample of the recipient's serum or plasma establishes the diagnosis.
Abstract. The first experiments in blood transfusion took place in the seventeenth century, using blood drawn from animals. After the death of a French patient and the trial of his physician for manslaughter, transfusion was abandoned for a century and a half.he first experiments in blood transfusion took place in the seventeenth century, using blood drawn from animals. After the death of a French patient and the trial of his physician for manslaughter, transfusion was abandoned for a century and a half.