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Hypersecretion of growth hormone causes gigantism in children and acromegaly in adults. Evaluation of growth hormone hypersecretion cannot be excluded with a single normal GH level due to diurnal variation.However, a random blood sample showing markedly elevated GH is adequate for diagnosis of GH hypersecretion.n humans, this condition is caused by over-production of growth hormone in childhood resulting in persons between 2.13 m (7 feet or 84 inches) and 2.74 m (9 feet or 108 inches) in height.
Acromegaly is a disorder caused by excess levels of growth hormone, commonly as a result of a tumour in a personâs pituitary gland. It causes an irreversible overgrowth of bones, particularly those of the face, hands and feet. The personâs skin is also affected and becomes thick, coarse and hairy.