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Risk factors for bladder cancer. A risk factor is something that increases the risk of developing cancer. It could be a behaviour, substance or condition. Most cancers are the result of many risk factors. Smoking is the most important risk factor for bladder cancer. The risk of developing bladder cancer increases with age. It usually occurs in people older than 65 years of age. Bladder cancer is most common in Caucasians, and men develop this disease more often than women.
Although we do not know all the causes of kidney cancer, the following factors may increase the risk of developing this disease: 1  Age. The risk of kidney cancer significantly increases with age, most kidney cancers occur in people over 45 years of age; with the highest incidences between the ages of 55 and 84. 2  Gender.