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There are several different types of globin chains, named alpha, beta, delta, and gamma. Normal hemoglobin types include: 1  Hemoglobin A (Hb A): makes up about 95%-98% of hemoglobin found in adults; it contains two alpha (Î±) chains and two beta (Î²) protein chains.
Hemoglobin is the main protein in mature red blood cells. Each RBC contains over 600 million hemoglobin molecules. It is tetramer, that is, one molecule of hemoglobin in adult is composed of four globin chains, 2 alpha and 2 beta. These chains are derived from chromosome, mainly chromosome 16 and 11. During the various stages of life such as embryonic, fetal and adult stages, different globin chains are expressed.