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Risk factors for bladder cancer. A risk factor is something that increases the risk of developing cancer. It could be a behaviour, substance or condition. Most cancers are the result of many risk factors. Smoking is the most important risk factor for bladder cancer. The risk of developing bladder cancer increases with age. It usually occurs in people older than 65 years of age. Bladder cancer is most common in Caucasians, and men develop this disease more often than women.
Other factors associated with increased bladder cancer risk include chronic bladder irritation and infections, cancer in any part of the urinary tract lining, bladder birth defects, and genetic mutations for bladder cancer.ladder cancer (BC) most commonly strikes men, and is the fourth leading type of cancer in males. Most people who will get this cancer are older than 55, and risk increases with age.