Amikacin was patented in 1971 and came into commercial use in 1976. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is 13.80 to 130.50 USD for a month.
olfactory. pertaining to smell. olfactory nerve the first cranial nerve; it is purely sensory and is concerned with the sense of smell. The nerve cell bodies are situated in the olfactory area of the mucous membrane of the nose.lfactory system. includes the olfactory part of the nasal mucosa, the olfactory nerves and the olfactory bulbs of the cerebrum. olfactory tract. a band of white nerve fibers visible on the ventral surface of the brain running caudally from the olfactory bulbs.
Olfactory sensory neurons project axons to the brain within the olfactory nerve, (cranial nerve I). These nerve fibers, lacking myelin sheaths, pass to the olfactory bulb of the brain through perforations in the cribriform plate, which in turn projects olfactory information to the olfactory cortex and other areas.lfaction, along with taste, is a form of chemoreception. The chemicals themselves that activate the olfactory system, in general at very low concentrations, are called odorants. Although taste and smell are separate sensory systems in land animals, water-dwelling organisms often have one chemical sense.