environment applies to all the external factors that have a formative influence on one's physical, mental, or moral development. the kind of environment that produces juvenile delinquents; milieu applies especially to the physical and social surroundings of a person or group of persons.
Myocardial ischemia is an imbalance between myocardial oxygen supply and demand. Left untreated, it results in angina pectoris, myocardial stunning, myocardial hibernation, ischemic preconditioning, postconditioning, or under the most severe instances, acute coronary syndrome and myocardial infarction.
Ischemia at this critical threshold level for an extended period results in irreversible myocardial cell damage or death. Critical myocardial ischemia can occur as a result of increased myocardial metabolic demand, decreased delivery of oxygen and nutrients to the myocardium via the coronary circulation, or both.