Admission to graduate programs is competitive. Selection criteria differ by program and are established by departmental faculty. Applicants are evaluated on the strength of their academic background, results of standardized exams (if required by the program), work experience, and any additional evidence of potential success in the program.
Aortic insufficiency (AI), also known as aortic regurgitation (AR), is the leaking of the aortic valve of the heart that causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle. As a consequence, the cardiac muscle is forced to work harder than normal.
21 Serious vs Severe Serious : â Serious AEâ is a regulatory definition (21 CFR 312.32) Severe :Severe is defined as an intensity classification (mild, moderate, severe) Severe AE â Serious AE. 22 Assessment of Relatedness In a clinical trial the study product/intervention must always be suspect.1 Pre-existing Conditions Pre-existing condition is not an AE EXCEPT when it increases in severity or frequencyExample: A patient at baseline with mild asthma, continues to have mild asthma throughout study period: not an AE.Example: Same patient is hospitalized with severe asthma: is a serious adverse event.