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Hypersecretion of growth hormone causes gigantism in children and acromegaly in adults. Evaluation of growth hormone hypersecretion cannot be excluded with a single normal GH level due to diurnal variation.However, a random blood sample showing markedly elevated GH is adequate for diagnosis of GH hypersecretion.n humans, this condition is caused by over-production of growth hormone in childhood resulting in persons between 2.13 m (7 feet or 84 inches) and 2.74 m (9 feet or 108 inches) in height.
Acromegaly is a rare disease typically caused by a noncancerous tumor in the pituitary gland. Acromegaly is caused by the excess secretion of growth hormone (GH). It can cause noticeable changes in your appearance, such as enlarged hands, feet, and facial features, and increased spaces between teeth. It also can affect your metabolism.