Incontinence-associated dermatitis (IAD) is predominantly a chemical irritation resulting from urine or stool coming in contact with the skin. Ammonia from urine and enzymes from stool can disrupt the acid mantle of the skin and eventually cause the skin to break down. As with the other forms of MASD discussed above, maceration also plays a key role in the formation of IAD, and can makes the skin more susceptible to friction damage.
DNA Replication. DNA replication is a process wherein copies of DNA molecules are produced within the cell nucleus. This replication process is vital because it facilitates the transfer of genetic information from one generation to another.he DNA replication process is a procedure wherein the DNA double helix splits and duplicates itself to make copies of the strands of DNA.
The replication fork is a structure that forms within the nucleus during DNA replication. It is created by helicases, which break the hydrogen bonds holding the two DNA strands together. The resulting structure has two branching prongs, each one made up of a single strand of DNA.he leading strand is the strand of nascent DNA which is being synthesized in the same direction as the growing replication fork. A polymerase reads the leading strand template and adds complementary nucleotides to the nascent leading strand on a continuous basis.