1 The medicine may be given every six to eight hours, as needed, up to 40 mg per kg per day. 2  Infants younger than 6 months of ageâUse and dose must be determined by your doctor. 3  For menstrual cramps: 4  Adultsâ400 milligrams (mg) every four hours, as needed.
Diclofenac and misoprostol combination is used to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis) in patients who may develop stomach ulcers from taking nonsteroidal anti-inflammatory drugs (NSAIDs).
To make sure you can safely take diclofenac and misoprostol, tell your doctor if you have any of these other conditions: 1  a history of heart attack, stroke, or blood clot; 2  heart disease, congestive heart failure, high blood pressure; 3  a history of stomach ulcers or bleeding;