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Hypersecretion of growth hormone causes gigantism in children and acromegaly in adults. Evaluation of growth hormone hypersecretion cannot be excluded with a single normal GH level due to diurnal variation.However, a random blood sample showing markedly elevated GH is adequate for diagnosis of GH hypersecretion.n humans, this condition is caused by over-production of growth hormone in childhood resulting in persons between 2.13 m (7 feet or 84 inches) and 2.74 m (9 feet or 108 inches) in height.
Hypersecretion of human growth hormone (GH) by the pituitary before puberty resulting in abnormal and accelerated growth is. acromegaly. Hypersecretion of GH that causes overgrowth of the hands and feet, abnormal thickening of the bones of the face, the excessive overgrowth of soft tissue, occurring after puberty.