adjective. 1  regardless of sin reparar en; buy it regardless of the cost cÃ³mpralo, cueste lo que cueste; they shot them all regardless of rank los fusilaron a todos sin miramientos a su graduaciÃ³n; we did it regardless of the consequences lo hicimos sin tener en cuenta las consecuencias.
Yes, their are two active ingredients in tramacet. Tramadol hydrochloride and paracetamol. Tramadol hydrochloride is an opioid and is closely related to morphine. It is actually synthetic form of morphine.
Codeine, morphine, and meperidine are the opioids most commonly associated with pseudoallergy. Use of a more potent opioid is less likely to result in histamine release. The potency of opioids, from lower to higher: meperidine < codeine < morphine < hydrocodone < oxycodone < hydromorphone < fentanyl.