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During the digestive period, intestinal phase signals stimulate the release of bile into the small intestine. Fatty acids in the lumen of the duodenum stimulate endocrine cells to release the hormone cholecystokinin (CCK). CCK stimulates contractions in the smooth muscle of the gallbladder. Views.
A polypeptide hormone produced principally by the small intestine in response to the presence of fats, causing contraction of the gallbladder, release of bile, and secretion of pancreatic digestive enzymes.Also called pancreozymin. gastrointestinal hormone liberated from the intestinal mucosa in response to arrival of the products of digestion from the stomach. It stimulates secretion of pancreatic enzymes and gallbladder contraction. Abbreviated CCK, CCK-PZ. Called also cholecystokinin-pancreozymin, pancreozymin.