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Patients with cardiomyopathy, a stiffening and thickening of the heart muscle that weakens it, may develop an enlarged heart as it labors to pump an adequate supply of blood to the body. Coronary artery disease, in which plaque in the arteries interferes with the flow of blood, can cause the heart to enlarge.
The heart enlarges because of damage to the heart muscle. Up to a point, an enlarged heart can still pump blood normally. As the condition progresses, though, the heart's pumping ability declines. Dilated cardiomyopathy is the main type of enlarged heart. The walls of both sides (also known as ventricles) become thin and stretched. This enlarges your heart.