Biography and career. Satterfield was born Louis Edward in Shaw, Mississippi, a city in Bolivar and Sunflower counties, Mississippi, in the Mississippi Delta region, on April 3, 1937.
Excitation-contraction coupling (ECC) is the process whereby an action potential triggers a myocyte to contract.When a myocyte is depolarized by an action potential, calcium ions enter the cell during phase 2 of the action potential through L-type calcium channels located on the sarcolemma.hen calcium binds to the TN-C, this induces a conformational change in the regulatory complex such that troponin-I (TN-I) exposes a site on the actin molecule that is able to bind to the myosin ATPase located on the myosin head.
Muscle Fiber Excitation. The events already described (calcium entry, cross-bridge cycling) occur when a muscle fiber is excited to fire an action potential. An action potential is triggered in a muscle fiber when it is depolarized due to excitation at its synapse, the neuromuscular junction.Each muscle fiber has one neuromuscular junction, receiving input from just one somatic efferent neuron.Ch binds to nicotinic receptors in a specialized region of the muscle fiber known as the motor endplate. ACh binding allows Na + ions to enter the cell, causing a depolarizing excitatory postsynaptic potential (EPSP) that is above threshold and triggers an action potential.