This factor works with calcium and Christmas factor to enable activation of Stuart factor. It is solely activated by thrombin that originates from platelets and endothelium lining of blood vessels. It is intrinsic in pathway. Anti-hemophilic factor A and globulin are its other designations.
Shock (circulatory) Circulatory shock, commonly known as shock, is a life-threatening medical condition of low blood perfusion to tissues resulting in cellular injury and inadequate tissue function.
Shock: In medicine, a critical condition that is brought on by a sudden drop in blood flow through the body. The circulatory system fails to maintain adequate blood flow, sharply curtailing the delivery of oxygen and nutrients to vital organs.