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Risk factors for bladder cancer. A risk factor is something that increases the risk of developing cancer. It could be a behaviour, substance or condition. Most cancers are the result of many risk factors. Smoking is the most important risk factor for bladder cancer. The risk of developing bladder cancer increases with age. It usually occurs in people older than 65 years of age. Bladder cancer is most common in Caucasians, and men develop this disease more often than women.
At present, there are several possible ways in which alcohol may raise the risk of cancer. Some of these theories include: Increasing estrogen levels: We know that increased estrogen levels can elevate the risk of breast cancer, and the metabolism of alcohol in the body can increase estrogen levels. Oxidative stress: Oxidative stress - or damage to DNA that occurs via reactions involving oxygen may contribute.