Biography and career. Satterfield was born Louis Edward in Shaw, Mississippi, a city in Bolivar and Sunflower counties, Mississippi, in the Mississippi Delta region, on April 3, 1937.
Excitation-contraction coupling (ECC) is the process whereby an action potential triggers a myocyte to contract.When a myocyte is depolarized by an action potential, calcium ions enter the cell during phase 2 of the action potential through L-type calcium channels located on the sarcolemma.hen calcium binds to the TN-C, this induces a conformational change in the regulatory complex such that troponin-I (TN-I) exposes a site on the actin molecule that is able to bind to the myosin ATPase located on the myosin head.
Excitationâcontraction coupling was a term coined in 1952 to describe the physiological process of converting an electrical stimulus to a mechanical response. This process is fundamental to muscle physiology, whereby the electrical stimulus is usually an action potential and the mechanical response is contraction.n contrast, a muscle contraction is isotonic if muscle length changes but the muscle tension remains the same. Furthermore, if the muscle length shortens, the contraction is concentric. But if the muscle length lengthens, then the contraction is eccentric.