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Anaphylactic reactions are excluded by the presence of red plasma or urine, discordant pretransfusion and posttransfusion ABO blood types, or a positive direct antiglobulin (Coombs) test result. Demonstration of anti-IgA in a pretransfusion sample of the recipient's serum or plasma establishes the diagnosis.
Introduction. A blood transfusion involves taking blood from one person (the donor) and giving it to someone else. You may need a blood transfusion for a number of reasons, including: 1  to replace blood lost during major surgery, childbirth or a severe accident. 2  to treat anaemia that has failed to respond to other treatments; anaemia is a condition where a person has low levels of red blood cells.