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Patients with cardiomyopathy, a stiffening and thickening of the heart muscle that weakens it, may develop an enlarged heart as it labors to pump an adequate supply of blood to the body. Coronary artery disease, in which plaque in the arteries interferes with the flow of blood, can cause the heart to enlarge.
Some heart rhythm disorders can cause a fluttering in the chest, shortness of breath, chest pain or dizziness. Hyperthyroidism Hyperparathyroidism can cause fatigue and weakness, increased thirst, impaired thinking, and bone fractures. Atrial flutter. Atrial flutter is an abnormality of the heart's rhythm that causes rapid and sometimes irregular heartbeats. Aortic stenosis. Aortic stenosis is a condition of the heart causing shortness of breath, dizziness, or chest pain.