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Risk factors for bladder cancer. A risk factor is something that increases the risk of developing cancer. It could be a behaviour, substance or condition. Most cancers are the result of many risk factors. Smoking is the most important risk factor for bladder cancer. The risk of developing bladder cancer increases with age. It usually occurs in people older than 65 years of age. Bladder cancer is most common in Caucasians, and men develop this disease more often than women.
Risk factors for gall bladder cancer include a  porcelain gallbladder , or calcium deposits in the wall of the gall bladder, and an abnormal pancreatic duct. Cholecystectomy can prevent the relapse of pancreatitis that is caused by gall stones that block the common bile duct.