In bacteria, transcription begins with the binding of RNA polymerase to the promoter in DNA. RNA polymerase is a core enzyme consisting of five subunits: 2 Î± subunits, 1 Î² subunit, 1 Î²' subunit, and 1 Ï subunit.
Untreated gout can cause a risk for diabetes and heart disease. Chronic gout can also cause kidney stones. Gout is caused by a buildup of uric acid in the blood. It cristalizes in the joints, with the big toe being the location in half of the cases. This is called podagra.
COLCRYS reduces gout attack pain. 1  Gout pain strikes hard, fast, and at any time, especially at night. 2  In a clinical study, COLCRYS reduced the pain of gout attacks by at least half. 3  COLCRYS is used for the treatment of gout flares. It is not a general pain medication, and it shouldn't be taken to relieve pain from other conditions.