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Risk factors for bladder cancer. A risk factor is something that increases the risk of developing cancer. It could be a behaviour, substance or condition. Most cancers are the result of many risk factors. Smoking is the most important risk factor for bladder cancer. The risk of developing bladder cancer increases with age. It usually occurs in people older than 65 years of age. Bladder cancer is most common in Caucasians, and men develop this disease more often than women.
Bladder cancer begins in the bladder lining. If it spreads beyond the bladder lining, it becomes more difficult to treat. Smoking is the single greatest risk factor for bladder cancer. According to the National Cancer Institute, there were 67,160 new cases of bladder cancer in 2007 and 13,750 bladder cancer-related deaths.