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RDW-CV and RDW-SD are a measurement of the size of red blood cells, according to Med-Health.net. RDW-SD is an actual measurement, while RDW-CV involves some calculations using the RDW-SD deviation.
A high RDW blood test result may indicate anemia due to either iron deficiency or a deficiency of folate and vitamin B12, according to Wikipedia. It may also be a result of a recent hemorrhage. False high RDW readings sometimes occur when the wrong type of blood is used for the test. As MedFriendly explains, other causes for a high RDW test result include liver disease and hemolytic anemia.