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All blood donations are processed and available for use usually within 24 hours. Whole blood is processed into components (red blood cells, platelets, plasma). After processing, the red blood cells can be stored for 42 days.
Qualified donors are allowed to donate whole blood every 8 weeks (56 days). So far that is the US standard safe interval which is an ample time for the body to replenish the lost blood and iron keeping the donor's health uncompromised.