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An enlarged heart is medically known as cardiomegaly. Cardiomegaly can be caused by a number of different conditions, including diseases of the heart muscle or heart valves, high blood pressure, arrhythmias, and pulmonary hypertension. Cardiomegaly can also sometimes accompany longstanding anemia and thyroid diseases, among other conditions. Infiltrative diseases of the heart, for example, in which abnormal proteins (amyloidosis) or excess iron (hemochromatosis) accumulate within the tissues of the heart, can also cause an enlargement of the heart.
High Blood Pressure. One of the most common reasons of enlarged heart is uncontrolled high blood pressure. High blood pressure makes the heart more stressed causing it to push itself harder to supply the blood to the entire body, which can often lead to the thickening and stiffening of the heart muscles.