Overwhelming evidence shows that testing drugs on animals is meaningless for humans, with a successful prediction rate for side effects of only 5-30%. For example, in a review of drugs withdrawn from the market (1960-90) only four out of 24 side effects were predicted by animal tests.he major reason new drugs are still tested on animals is to protect companies in court when people are injured or killed by adverse drug reactions. Pharmaceutical companies admit, in private and sometimes even in public, that animal testing is ineffective but is done because it provides liability protection.
Skin pigmentation disorders occur as a result of the body producing either too much or too little melanin. Skin pigmentation creates a darker or lighter skin tone that may be blotchy and uneven.Causes of skin pigmentation can range from auto immune conditions to drug reactions or genetic inheritance.ormonal therapy, childbirth or birth control pills can cause skin pigmentation changes. Many people suffer from skin pigmentation problems as a result of locally increased skin pigment production. They appear as age spots, moles, liver spots or hyper pigmentation after local skin damage.
If you have any doubt about a spot on your skin, have it checked out by a doctor or skin specialists. Skin Discoloration â Some Causes. The purpose of our bodies pigment is to absorb ultraviolet light from the sun and protect it from radiation damage. For some folks exposure to the sun produces a nice even tan. For others, particularly those with lighter skin tones, patchy areas of tanned skin or an increase in freckles is more than likely. Simply getting older can cause skin to change color. Melanin is the compound that takes care of how much pigment is produced, and as people get older, like a lot of other things, melanin production often gets a little off kilter.