It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma. EC 2.3.1.43.
The chickenpox vaccine is a shot that can protect nearly anyone who receives the vaccine from catching chickenpox. It's also called the varicella vaccine, because chickenpox is caused by the varicella-zoster virus. The vaccine is made from a live but weakened, or attenuated, virus.lthough the virus in the chickenpox vaccine is generally incapable of causing a disease, it still stimulates a response from the body's immune system. That response is what gives someone who's had a shot for chickenpox immunity or protection from the illness.
Varicella is a live-attenuated vaccine. This means it's a live virus that's been weakened so that it's unlikely to cause the disease. Instead, the virus will replicate in the cells of the body and cause the body to produce an immune response, which should protect against a real chicken pox infection. Chicken pox can be serious and even deadly. 2  Before the vaccine, chicken pox caused an average of 10,600 hospitalizations and 100 to 150 deaths a year in the United States. 3  Complications included pneumonia and severe skin infections, and most deaths occurred in previously healthy people.