I recently completed a roof project for a relative. This was roof #3 for the home- tore off the previous two layers. The home is about 40 years old with roof trusses and 1/2 (maybe 7/16) plywood sheathing, no clips. Plenty of roof and eave ventilation. As expected, the roof deck seemed to be quite brittle. A 220# guy with a bundle of shingles in hand could have stepped through the roof quite easily.
DSLR Definition: Digital Single Lens Reflex Camera. The Nikon D3000 is a DSLR camera. A DSLR, or digital single lens reflex camera is an advanced type of digital camera that provides high-level image quality, performance levels, and manual control options, typically much better than what you'd receive with a fixed lens camera.
Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system.They are single, membrane-spanning, non-catalytic receptors usually expressed in sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes.oth TLR3 and TLR4 utilize the TRIF-dependent pathway, which is triggered by dsRNA and LPS, respectively. For TLR3, dsRNA leads to activation of the receptor, recruiting the adaptor TRIF. TRIF activates the kinases TBK1 and RIPK1, which creates a branch in the signaling pathway.