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From Wikipedia, the free encyclopedia. Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
A gastrin test measures the level of the hormone gastrin in the blood. Gastrin is produced by cells, called G cells, in the stomach lining. When food enters the stomach, G cells trigger the release of gastrin in the blood.As blood levels of gastrin rise, the stomach releases acid (gastric acid) that helps break down and digest food.When enough gastric acid has been produced by the stomach, gastrin levels in the blood drop.hen food enters the stomach, G cells trigger the release of gastrin in the blood. As blood levels of gastrin rise, the stomach releases acid (gastric acid) that helps break down and digest food. When enough gastric acid has been produced by the stomach, gastrin levels in the blood drop.