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Clostridium difficile is a gram-positive, anaerobic, spore-forming bacillus that is responsible for the development of antibiotic-associated diarrhea and colitis. C difficile infection (CDI) commonly manifests as mild to moderate diarrhea, occasionally with abdominal cramping.
Clostridium difficile, also known as C. difficile, or C. diff, is a bacterium which infects and can make humans ill, as well as other animals. Symptoms can range from diarrhea to serious and potentially fatal inflammation of the colon.igns and symptoms in more severe cases may include: C. diff infection can be fatal; however, this is very rare. The risk of a life-threatening condition is higher among very elderly patients, as well as individuals with existing serious health conditions.