Cyclodextrins are cyclic a-(1-4) -linked maltooligosaccharides. a-, p-, and y-cyclodextrin consist of 6, 7, and 8 glucose units, respectively. Cyclodextrins were first isolated by Villiers in 189 1 from a culture medium of Bacillus amylobacter (Clostridium butvricum) grown on a medium containing starch.During studies on microbial food spoilage, Schardinger isolated Bacillus macerans, a heat-resistant cyclodextrin-producing microorganism.yclodextrins were first isolated by Villiers in 189 1 from a culture medium of Bacillus amylobacter (Clostridium butvricum) grown on a medium containing starch. During studies on microbial food spoilage, Schardinger isolated Bacillus macerans, a heat-resistant cyclodextrin-producing microorganism.
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