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prostate specific antigen, PSA (noun). a protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer.see more on Definitions.net Â». protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer. see more on Definitions.net Â».
What is the PSA test? Prostate-specific antigen, or PSA, is a protein produced by cells of the prostate gland. The PSA test measures the level of PSA in a manâs blood. For this test, a blood sample is sent to a laboratory for analysis. The results are usually reported as nanograms of PSA per milliliter (ng/mL) of blood.