New dance craze Harlem Shake spreads across internet. 1  The Harlem Shake is the latest dance meme taking the internet by storm. 2  Follows the huge success of K-pop rapper Psyâs 2012 hit. 3  Videos are about 30 seconds long, set to Harlem Shake by DJ Baauer.
Other antiplatelet regimens â Prior to the randomized trials of NOAC agents (see 'Select an anticoagulant' above), alternatives to warfarin (or aspirin) monotherapy using various antiplatelet regimens were studied, including low-dose warfarin plus aspirin, and aspirin plus clopidogrel.
Mechanism of action of novel oral anticoagulants. Unlike traditional anticoagulant agents, the VKAs and heparins, novel OACs have been designed to inhibit specific single targets in the coagulation cascade (Figure 1) [9]. Rivaroxaban and apixaban directly inhibit Factor Xa, whereas dabigatran targets thrombin (Factor IIa).