Huntgoddess.....yes, I agree that many people seem to think Jack and Rose were real and yes, what I'm saying is that the fictional character of Rose was modeled after the very real Beatrice Wood. The very real Beatrice Wood had nothing to do with the Titanic.
Fampridine is a lipid-soluble medicinal product which readily crosses the blood-brain barrier. Fampridine is largely unbound to plasma proteins (bound fraction varied between 3-7% in human plasma). Fampridine has a volume of distribution of approximately 2.6 l/kg. Fampridine is not a substrate for P-glycoprotein.
FirdapseÂ® is amifampridine phosphate or 3,4-diaminopyridine phosphate (3,4-DAP). It has received an orphan drug designation in the U.S. and orphan medicinal product designation in the European Union for the treatment of Lambert-Eaton Myasthenic Syndrome (LEMS).