To research the causes of Erdheim-Chester Disease, consider researching the causes of these these diseases that may be similar, or associated with Erdheim-Chester Disease: 1  Polyostotic sclerosing histiocytosis. 2  Bone pain. 3  Retroperitoneal fibrosis. 4  Diabetes insipidus. 5  Exophthalmos. 6  Dyspnea. 7  Ataxia.
1 The optimal temperature for Taq polymerase is about 75-80 o C, but it is partially active even at typical annealing temperatures so primer extension begins during the annealing step. 2  The rate of primer extension by Taq polymerase is about 50-100 nucleotides/sec.
A pH of about 7 is the optimum and as the pH moves further away from the optimum pH the enzyme activity starts to slow down. Every enzyme shows highest activity at a specific temperature which is called the optimum temperature. The rate of reaction above or below this temperature is slower. Increasing the temperature causes the frequency of collisions to increase as the molecules move faster when the heat is supplied.