Mechanism of action. Aminoglycosides like neomycin irreversibly bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit.This region interacts with the wobble base in the anticodon of tRNA.pecifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA.
Inflammation of the surface of the eye (conjunctivitis) and inflammation of the eyelids (blepharitis) are common causes of swollen eyes. Other common causes include crying, lack of sleep, or excessive rubbing of the eyes. Wearing contact lenses can also result in eye swelling. Depending on the cause, swelling may occur in one or both eyes, and it may be accompanied by redness, pain, itching, excessive tear production, or other types of discharge from the affected eyes.
1 Mosquito bites are a common cause. It can also be from an irritant (e.g. food) transferred to the eye by the hands.  Suspect mosquito bites if there are bites on other parts of the body. Insect bites of the upper face can cause the eyelid to swell.