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What Is an Institutional Review Board (IRB)? An IRB is a committee within a university or other organization receiving federal funds to conduct research that reviews research proposals. The IRB reviews the proposals before a project is submitted to a funding agency to determine if the research project follows the ethical principles and federal regulations for the protection of human subjects. The IRB has the authority to approve, disapprove or require modifications of these projects.
The institution that the IRB serves provides administrative support for its activities including designation of an individual within the institution to oversee research and IRB functions. The institution also files an Assurance with the federal government that describes the procedures and guidelines that the IRB must follow.