When DNA replication starts, one primer is needed at the start of the leading strand. The lagging strand will need new primers regularly, and they mark the start of the stretches known as Okazaki fragments.
The recommended dose of Alimta is 500 mg/m2 administered as an intravenous infusion over 10 minutes on Day 1 of each 21-day cycle. The recommended dose of cisplatin is 75 mg/m2 infused over 2 hours beginning approximately 30 minutes after the end of Alimta administration. See cisplatin package insert for more information.
With others, it is given every day for 14 days, or weekly for 2 weeks. Then, at the end of the cycle, the chemo schedule repeats to start the next cycle. Cycles are most often 2 or 3 weeks long, but they vary according to the specific drug or combination of drugs. Some drugs are given more often.Adjuvant and neoadjuvant chemo is often given for a total of 3 to 6 months, depending on the drugs that are used. Treatment may be longer for advanced breast cancer and is based on how well it is working and what side effects you have.ith others, it is given every day for 14 days, or weekly for 2 weeks. Then, at the end of the cycle, the chemo schedule repeats to start the next cycle. Cycles are most often 2 or 3 weeks long, but they vary according to the specific drug or combination of drugs. Some drugs are given more often.