Symptoms of Spinal Tumors. Symptoms of spinal tumors depend on the location and type of tumor. In general, symptoms of spinal tumors include: 1  Back pain. 2  Unusual feelings in the legs, such as numbness or tingling. 3  Problems with bowel or bladder control. 4  Weakness in the muscles, especially the legs.
There are three reasons to conduct a bioburden recovery test: to evaluate the test procedure in order to improve recovery, to assess antimicrobial qualities of the product against certain organisms, or merely to establish a recovery factor for adjusting future bioburden data.
Timely results for microbial bioburden monitoring of in-process cell culture samples are critical to the production process for recombinant proteins and other biopharmaceutical products.