Mechanism of action. Aminoglycosides like neomycin irreversibly bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit.This region interacts with the wobble base in the anticodon of tRNA.pecifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA.
Inflammation of the surface of the eye (conjunctivitis) and inflammation of the eyelids (blepharitis) are common causes of swollen eyes. Other common causes include crying, lack of sleep, or excessive rubbing of the eyes. Wearing contact lenses can also result in eye swelling. Depending on the cause, swelling may occur in one or both eyes, and it may be accompanied by redness, pain, itching, excessive tear production, or other types of discharge from the affected eyes.
Heredity and Age: Individuals with family history of swollen under eyes are more prone to it and are likely to develop it at some point in life. Aging is another contributing factor towards the occurrence of puffy under eyes. Injury: Injury close to eyes or around the eyelids can also cause the eyes to swell.