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Clostridium difficile is a gram-positive, anaerobic, spore-forming bacillus that is responsible for the development of antibiotic-associated diarrhea and colitis. C difficile infection (CDI) commonly manifests as mild to moderate diarrhea, occasionally with abdominal cramping.
â¢ Promptly identify patients with C diff. Patients will exhibit clinical symptoms (watery diarrhea, fever, nausea, abdominal pain or tenderness, loss of appetite) and test positive for the C diff organism or its toxin. â¢ Place patients with C diff in private rooms or isolate them with other patients with C diff infections.