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The usual total daily dose is 200 mg to 400 mg in two divided doses. Some patients may require doses up to 800 mg per day which is the maximum dose. It is recommended that therapy be initiated at a low dose, followed by titration to an effective dose.
Please refer to the dosing table for calculations regarding GATTEX dose. Dosing. â¢ The recommended daily dose of GATTEX is 0.05 mg/kg1. â¢ Reduce the dose by 50% in patients with moderate and severe renal impairment (creatinine clearance less than 50 mL/min), and end-stage renal disease1. â¢ Milliliter dosing is calculated by dividing the weight of the patient (kg) by 200.