2. R EGIONAL S ETTING The Mumbai Metropolitan Region extends over an area of 4355 sq. km and comprises Municipal Corporations of Greater Mumbai, Thane, Kalyan, Navi Mumbai and Ulhasnagar; 15 municipal towns; 7 non-municipal urban centers; and 995 villages.. R EGIONAL S ETTING The Mumbai Metropolitan Region extends over an area of 4355 sq. km and comprises Municipal Corporations of Greater Mumbai, Thane, Kalyan, Navi Mumbai and Ulhasnagar; 15 municipal towns; 7 non-municipal urban centers; and 995 villages.
PROPHASE: During the prophase the nucleoli in the nucleus disappear. The chromatin fibers become tightly ccoiled and condense into chromosomes. Chromosomes line up in pairs and are joined at the centromere. In the cytoplasm, the spindle fibers begin to form and are made of microtubules. The centrosomes move away from each other, propelled by the lengthening microtubules, or spindle fibers, between them.
Chromosomes are made up of a DNA-protein complex called chromatin that is organized into subunits called nucleosomes. The way in which eukaryotes compact and arrange their chromatin not only allows a large amount of DNA to fit in a small space, but it also helps regulate gene expression.eBooks.ach chromosome contains a single double-stranded piece of DNA along with the aforementioned packaging proteins. Figure 1: Chromatin condensation changes during the cell cycle. During interphase (1), chromatin is in its least condensed state and appears loosely distributed throughout the nucleus.