Early cases of BXO can appear similar to those of candidal balanitis or to those of one of the various penile dermatoses, such as vitiligo, scleroderma, or erythroplasia of Queyrat. Although physical findings can suggest BXO, cutaneous biopsy and histology are needed to make a definitive diagnosis (Figure 4).
The Apennines form the backbone of the country running down the full length of the Italian peninsula from the Cadibona Pass to the tip of Calabria, continuing onto the island of Sicily. The range is about 2,000 kilometres long.
The Mediterranean peninsula. Italy, meaning the entire peninsula south of the Alps, is known as such from about the 1st century BC. Several centuries earlier, when the name first appears, it is used only of the area in the extreme south - the toe of the peninsula.