Mechanism of action. Aminoglycosides like neomycin irreversibly bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit.This region interacts with the wobble base in the anticodon of tRNA.pecifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA.
Swelling of Eye: Clues to the Cause. 1  Swelling of 1 eye is often due to an insect bite. 2  Suspect mosquito bites if there are bites on other parts of the body. 3  Swelling of both eyes is usually due to pollen that's airborne.  Swelling of the face is usually due to allergic reactions to swallowed substances.
Puffy eyes generally result from a variety of factors, including: 1  Overconsumption of salt, which causes fluid retention. 2  Allergies that can cause inflammation and swelling. 3  Sinus problems. 4  Dehydration. 5  Fatigue and lack of sleep. 6  Stress. 7  Crying. 8  Aging. 9  Inherited facial features.