Gravette, Arkansas. Gravette is a city in Benton County, Arkansas, United States. The population was 2,325 at the 2010 census. It is part of the FayettevilleâSpringdaleâRogers, AR-MO Metropolitan Statistical Area.
congenital nephrotic syndrome. At least 170 mutations in the NPHS2 gene have been found to cause congenital nephrotic syndrome. This condition is a kidney disorder that begins in infancy and typically leads to irreversible kidney failure (end-stage renal disease) by early childhood.
Researchers have not determined how mutations in the PKHD1 gene lead to the formation of numerous cysts characteristic of polycystic kidney disease. Although polycystic kidney disease is usually a genetic disorder, a small percentage of cases are not caused by gene mutations.