Transform Plate Boundaries. Transform Plate Boundaries are locations where two plates slide past one another. The fracture zone that forms a transform plate boundary is known as a transform fault. Most transform faults are found in the ocean basin and connect offsets in the mid-ocean ridges.
Laminin function and loss-of-function studies. Laminin exerts many different functions, including embryogenesis, vascular maturation, and neuromuscular development [8, 34, 35, 37, 38, 39, 40, 41]. These functions are highly dependent on laminin isoforms, their cellular sources, and developmental stages.
The smallest laminin G domain can be found in one of the collagen proteins (COL24A1; 77 AA) and the largest domain in TSPEAR (219 AA). The exact function of the Laminin G domains has remained elusive, and a variety of binding functions has been ascribed to different Laminin G modules. For example, the laminin alpha1 and alpha2 chains each have five C-terminal laminin G domains, where only domains LG4 and LG5 contain binding sites for heparin, sulphatides and the cell surface receptor dystroglycan.