Mechanism of action. Aminoglycosides like neomycin irreversibly bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit.This region interacts with the wobble base in the anticodon of tRNA.pecifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA.
Swelling of Eye: Clues to the Cause. 1  Swelling of 1 eye is often due to an insect bite. 2  Suspect mosquito bites if there are bites on other parts of the body. 3  Swelling of both eyes is usually due to pollen that's airborne.  Swelling of the face is usually due to allergic reactions to swallowed substances.
In addition to the disorders listed in Some Causes of Eyelid Swelling, eyelid swelling may result from the following: Disorders that may involve the eyelid but do not cause swelling unless very advanced (eg, eyelid tumors, including squamous cell carcinomas and melanoma) Disorders that cause swelling that begins and is usually most severe in structures near, but not part of, the eyelids (eg, dacryocystitis, canaliculitis) Disorders in which swelling occurs but is not the presenting symptom (eg, basilar skull fracture, burns, trauma, postsurgery)