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Nitrates are one of a type of drug known as vasodilators, that are used to treat angina in people with coronary artery disease or chest pain caused by blocked blood vessels of the heart. They work to control angina by relaxing the coronary arteries so blood can flow more easily to the heart.
How It Works. Nitrates open (dilate) the arteries to the heart. This increases blood flow to the heart, relieving angina symptoms such as chest pain or pressure. Nitrates also dilate veins throughout the body so that they can hold more blood.This reduces the amount of blood going back to the heart, reducing the heart's workload.ide Effects. All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.