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The condition leads to hormone imbalances that affect a woman's menstrual cycle â and can lead to excess body hair growth and acne. Women with this condition are resistant to insulin, which may cause weight gain. The weight tends to gravitate to the abdomen, putting women at greater risk of heart disease.
So estrogen can be directly responsible for weight gain. Estrogen is also the hormone in the female body responsible for ovulation. It is the reason women can produce eggs and these eggs fertilize with sperm to form a baby. Estrogen can increase due to many reasons including birth control pills and menopause. Birth control pills add to the existing hormone in the body and increase the womanâs appetite. This, in turn, leads to weight gain. In the case of menopause, hormonal fluctuations lead to an increase in appetite and eventual weight gain. During menopause, the body rapidly produces lesser hormones to stop ovulation.