2. R EGIONAL S ETTING The Mumbai Metropolitan Region extends over an area of 4355 sq. km and comprises Municipal Corporations of Greater Mumbai, Thane, Kalyan, Navi Mumbai and Ulhasnagar; 15 municipal towns; 7 non-municipal urban centers; and 995 villages.. R EGIONAL S ETTING The Mumbai Metropolitan Region extends over an area of 4355 sq. km and comprises Municipal Corporations of Greater Mumbai, Thane, Kalyan, Navi Mumbai and Ulhasnagar; 15 municipal towns; 7 non-municipal urban centers; and 995 villages.
PROPHASE: During the prophase the nucleoli in the nucleus disappear. The chromatin fibers become tightly ccoiled and condense into chromosomes. Chromosomes line up in pairs and are joined at the centromere. In the cytoplasm, the spindle fibers begin to form and are made of microtubules. The centrosomes move away from each other, propelled by the lengthening microtubules, or spindle fibers, between them.
For a complete description of the events during Interphase, read about the Cell Cycle. Prophase: During this first mitotic stage, the nucleolus fades and chromatin (replicated DNA and associated proteins) condenses into chromosomes. Each replicated chromosome comprises two chromatids, both with the same genetic information. Microtubules of the cytoskeleton, responsible for cell shape, motility and attachment to other cells during interphase, disassemble.