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From Wikipedia, the free encyclopedia. Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
A hormone released by the stomach and the small intestine when you eat. Gastrin stimulates the release hydrochloric acid and pepsinogen in the stomach, and it speeds up digestion. Also, gastrin stimulates glucagon, a hormone that works with insulin to regulate blood sugar. Secretin.