Overwhelming evidence shows that testing drugs on animals is meaningless for humans, with a successful prediction rate for side effects of only 5-30%. For example, in a review of drugs withdrawn from the market (1960-90) only four out of 24 side effects were predicted by animal tests.he major reason new drugs are still tested on animals is to protect companies in court when people are injured or killed by adverse drug reactions. Pharmaceutical companies admit, in private and sometimes even in public, that animal testing is ineffective but is done because it provides liability protection.
Skin pigmentation disorders occur as a result of the body producing either too much or too little melanin. Skin pigmentation creates a darker or lighter skin tone that may be blotchy and uneven.Causes of skin pigmentation can range from auto immune conditions to drug reactions or genetic inheritance.ormonal therapy, childbirth or birth control pills can cause skin pigmentation changes. Many people suffer from skin pigmentation problems as a result of locally increased skin pigment production. They appear as age spots, moles, liver spots or hyper pigmentation after local skin damage.
However, there are also other factors that can increase or decrease melanin production. Generally, there are two kinds of pigmentation abnormalities that can happen which are: 1  Hyperpigmentation â this is when melanin production is higher than normal, which causes the appearance of brown or tan spots on the skin.