Symptoms of Spinal Tumors. Symptoms of spinal tumors depend on the location and type of tumor. In general, symptoms of spinal tumors include: 1  Back pain. 2  Unusual feelings in the legs, such as numbness or tingling. 3  Problems with bowel or bladder control. 4  Weakness in the muscles, especially the legs.
There are three reasons to conduct a bioburden recovery test: to evaluate the test procedure in order to improve recovery, to assess antimicrobial qualities of the product against certain organisms, or merely to establish a recovery factor for adjusting future bioburden data.
Method Validation Summary. The laser scanner method for detecting bioburden in mammalian cell culture systems is being validated according to a master method validation plan. The validation consists of four phases: method evaluation, concurrent testing, method validation and crossover studies.