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How long do the effects last? In mild cases, diarrhea may last up to 14 days after you stop taking the antibiotic. If you have a more severe case, the symptoms may not go away until several weeks after you begin treatment. Sometimes the symptoms return in spite of treatment.
Signs and symptoms. Acute diarrhea is defined as the abrupt onset of 3 or more loose stools per day and lasts no longer than 14 days; chronic or persistent diarrhea is defined as an episode that lasts longer than 14 days.