2. R EGIONAL S ETTING The Mumbai Metropolitan Region extends over an area of 4355 sq. km and comprises Municipal Corporations of Greater Mumbai, Thane, Kalyan, Navi Mumbai and Ulhasnagar; 15 municipal towns; 7 non-municipal urban centers; and 995 villages.. R EGIONAL S ETTING The Mumbai Metropolitan Region extends over an area of 4355 sq. km and comprises Municipal Corporations of Greater Mumbai, Thane, Kalyan, Navi Mumbai and Ulhasnagar; 15 municipal towns; 7 non-municipal urban centers; and 995 villages.
PROPHASE: During the prophase the nucleoli in the nucleus disappear. The chromatin fibers become tightly ccoiled and condense into chromosomes. Chromosomes line up in pairs and are joined at the centromere. In the cytoplasm, the spindle fibers begin to form and are made of microtubules. The centrosomes move away from each other, propelled by the lengthening microtubules, or spindle fibers, between them.
DNA exists in Chromatin form in the nucleus. The chromatin condenses to form Chromosomes during cell division. Inside the nucleus. The chromatin in the nucleus forms a ' beads-on-string ' structure or Nucleosome. The 'beads' are octamer histone proteins and the 'string' is the double-stranded DNA.About 147 base pairs wrap around the 8-part histone protein to form a nucleosome. The nucleosomes condense to form a chromatin fiber.Chromatin fiber organises into Chromosomes upon cell division.The chromatin is elaborately arranged and paired in mitosis. Sister chromatids are formed in case of meiosis along with pairing.he nucleosomes condense to form a chromatin fiber. Chromatin fiber organises into Chromosomes upon cell division. The chromatin is elaborately arranged and paired in mitosis. Sister chromatids are formed in case of meiosis along with pairing.