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Blackouts can also be caused by a variety of drugs and other substances including: Alcohol intoxication. Medication side effects, such as the side effects of cancer treatments or seizure medications, or agents used for anesthesia. Poisons, such as cleaning chemicals or pesticides.
Other Causes of Blackouts. The other important causes of a blackout are epilepsy and a psychological cause. Whereas 50% of us may faint, only about 0.7% have epilepsy, so that a blackout is much more likely to be due to a faint than an epileptic attack.