When DNA replication starts, one primer is needed at the start of the leading strand. The lagging strand will need new primers regularly, and they mark the start of the stretches known as Okazaki fragments.
The recommended dose of Alimta is 500 mg/m2 administered as an intravenous infusion over 10 minutes on Day 1 of each 21-day cycle. The recommended dose of cisplatin is 75 mg/m2 infused over 2 hours beginning approximately 30 minutes after the end of Alimta administration. See cisplatin package insert for more information.
3 tablets. kg=kilogram; mg=milligram; ml=milliliter. Dose may be given every 6-8 hours. Do not give more than four doses within 24 hours. For children less than 6 months old: Ask the doctor for dosing instructions. For children 12 years old or older: Give 200 mg every 4-6 hours.If needed, you can increase the dose to 400 mg every 4-6 hours.o not give more than four doses within 24 hours. For children less than 6 months old: Ask the doctor for dosing instructions. For children 12 years old or older: Give 200 mg every 4-6 hours.