Overwhelming evidence shows that testing drugs on animals is meaningless for humans, with a successful prediction rate for side effects of only 5-30%. For example, in a review of drugs withdrawn from the market (1960-90) only four out of 24 side effects were predicted by animal tests.he major reason new drugs are still tested on animals is to protect companies in court when people are injured or killed by adverse drug reactions. Pharmaceutical companies admit, in private and sometimes even in public, that animal testing is ineffective but is done because it provides liability protection.
Skin pigmentation disorders occur as a result of the body producing either too much or too little melanin. Skin pigmentation creates a darker or lighter skin tone that may be blotchy and uneven.Causes of skin pigmentation can range from auto immune conditions to drug reactions or genetic inheritance.ormonal therapy, childbirth or birth control pills can cause skin pigmentation changes. Many people suffer from skin pigmentation problems as a result of locally increased skin pigment production. They appear as age spots, moles, liver spots or hyper pigmentation after local skin damage.
Melanocyte-stimulating hormone levels are also raised during pregnancy and in women using birth control pills, which can cause hyperpigmentation of the skin. Cushingâs syndrome, due to an excess production of adrenocorticotropic hormone, can also lead to hyperpigmentation.rint | Email article to a friend | Last updated: March 31, 2015. Melanocyte-stimulating hormone describes a group of hormones produced by the pituitary gland, hypothalamus and skin cells. It is important for protecting the skin from UV rays, development of pigmentation and control of appetite.