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From Wikipedia, the free encyclopedia. Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
Cephalic phase: the largest volume of secretion is produced. B) Gastric phase: gastrin secretion is inhibited by distention of the stomach. Gastric phase: initiated by chewing, swallowing, or thinking of food.