Transform Plate Boundaries. Transform Plate Boundaries are locations where two plates slide past one another. The fracture zone that forms a transform plate boundary is known as a transform fault. Most transform faults are found in the ocean basin and connect offsets in the mid-ocean ridges.
Laminin function and loss-of-function studies. Laminin exerts many different functions, including embryogenesis, vascular maturation, and neuromuscular development [8, 34, 35, 37, 38, 39, 40, 41]. These functions are highly dependent on laminin isoforms, their cellular sources, and developmental stages.
Laminins are high-molecular weight (~400 to ~900 kDa) proteins of the extracellular matrix. They are a major component of the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. The laminins are an important and biologically active part of the basal lamina, influencing cell differentiation, migration, and adhesion.