Early cases of BXO can appear similar to those of candidal balanitis or to those of one of the various penile dermatoses, such as vitiligo, scleroderma, or erythroplasia of Queyrat. Although physical findings can suggest BXO, cutaneous biopsy and histology are needed to make a definitive diagnosis (Figure 4).
The Apennines form the backbone of the country running down the full length of the Italian peninsula from the Cadibona Pass to the tip of Calabria, continuing onto the island of Sicily. The range is about 2,000 kilometres long.
The peninsula is bordered by the Tyrrhenian Sea on the west, the Ionian Sea on the south, and the Adriatic Sea on the east. The backbone of the Peninsula consists of the Apennine Mountains, from which it takes one of its names. Most of its coast is lined with cliffs. The Italian Peninsula's location between the centre of Europe and the Mediterranean Sea made it the target of many conquests.