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â Interphase (grey) is the longest phase which itself occurs in three stages. â G1 The cell performs its normal differentiated function. Protein synthesis/ mitochondria replication/ chloroplast replication. â S DNA replication. At this point the mass of DNA in the cell has doubled.
Prophase. The first and longest phase of mitosis is prophase. During prophase, chromatin condenses into chromosomes, and the nuclear envelope, or membrane, breaks down. In animal cells, the centrioles near the nucleus begin to separate and move to opposite poles of the cell. As the centrioles move, a spindle starts to form between them.