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Mutagenicity is a specific term that refers to a permanent, heritable change in the structure or amount of genetic material of an organism and includes gene mutations as well as structural and numerical alterations in chromosomes (Eastmond et al.
A carcinogen is an agent that induces neoplasia, i.e. cancer. Whatâs an agent? Chemicals, radiation, and viruses are among the agents implicated in causing cancer. A mutagen is a chemical that can cause changes (mutations) to the genetic material of a cell (DNA). A mutagen is one possible pathway to carcinogenesis. When mutations occur in germ cells (i.e. sperm or ova) it is possible for the mutation to be transmitted to offspring. A mutagen may be a carcinogen, but the link is not absolute. That is, not all chemicals shown to be mutagens are necessarily carcinogens. Conversely, not all carcinogens are mutagens. There are nongenotoxic carcinogensâchemicals that cause cancer by several mechanisms including by inducing sustained cell injury. Another important idea.