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From Wikipedia, the free encyclopedia. Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
hormone released by enteroendocrine cells that inhibits parietal and chief cell activity in the stomach; also targets the pancreas to stimulate production of bicarbonate ions and the liver to stimulate secretion of bile; released when chyme arrives in the duodenum.