It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma. EC 2.3.1.43.
The chickenpox vaccine is a shot that can protect nearly anyone who receives the vaccine from catching chickenpox. It's also called the varicella vaccine, because chickenpox is caused by the varicella-zoster virus. The vaccine is made from a live but weakened, or attenuated, virus.lthough the virus in the chickenpox vaccine is generally incapable of causing a disease, it still stimulates a response from the body's immune system. That response is what gives someone who's had a shot for chickenpox immunity or protection from the illness.
The inactivated polio, hepatitis A, influenza (shot) , and rabies vaccines are made this way. Because the virus is still seen by the body, cells of the immune system that protect against disease are generated. There are two benefits to this approach:1  The vaccine cannot cause even a mild form of the disease that it prevents. 2  The vaccine can be given to people with weakened immune systems.se part of the virus. Using this strategy, just one part of the virus is removed and used as a vaccine. The hepatitis B and the human papillomavirus (HPV) vaccines are made this way.