Mechanism of action. Aminoglycosides like neomycin irreversibly bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit.This region interacts with the wobble base in the anticodon of tRNA.pecifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA.
Swelling of Eye: Clues to the Cause. 1  Swelling of 1 eye is often due to an insect bite. 2  Suspect mosquito bites if there are bites on other parts of the body. 3  Swelling of both eyes is usually due to pollen that's airborne.  Swelling of the face is usually due to allergic reactions to swallowed substances.
Puffy, swollen eyelids and dark circles under the eyes can occur when you have an eye infection such as pink eye. These swollen eyes are caused by inflammation associated with the eye infection, which directly affects the neighboring eyelids. Also, dry eyes can cause general puffiness and swelling.