Huntgoddess.....yes, I agree that many people seem to think Jack and Rose were real and yes, what I'm saying is that the fictional character of Rose was modeled after the very real Beatrice Wood. The very real Beatrice Wood had nothing to do with the Titanic.
Fampridine is a lipid-soluble medicinal product which readily crosses the blood-brain barrier. Fampridine is largely unbound to plasma proteins (bound fraction varied between 3-7% in human plasma). Fampridine has a volume of distribution of approximately 2.6 l/kg. Fampridine is not a substrate for P-glycoprotein.
Nifedipine is a dihydropyridine calcium channel blocker that is widely used for the treatment of cardiovascular disorders in nonpregnant individuals. Over the last 15 years its favourable pharmacologic characteristics have resulted in its efficacy and safety being assessed in pregnancy.