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From Wikipedia, the free encyclopedia. Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
Gastrin is a linear peptide hormone produced by G cells of the duodenum and in the Pyloric antrum of the stomach. 1  It is secreted into the bloodstream. Gastrin is found primarily in three forms: 2  gastrin-34 (big gastrin) 3  gastrin-17 (little gastrin) 4  gastrin-14 (minigastrin)