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Clostridium difficile is a gram-positive, anaerobic, spore-forming bacillus that is responsible for the development of antibiotic-associated diarrhea and colitis. C difficile infection (CDI) commonly manifests as mild to moderate diarrhea, occasionally with abdominal cramping.
When there is an imbalance of bacteria in the intestine, Clostridium difficile may produce toxins that affect the lining of the bowel and give the symptoms of Clostridium difficile colitis. The symptoms usually include diarrhoea and cramping pain.