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Mutagenicity is a specific term that refers to a permanent, heritable change in the structure or amount of genetic material of an organism and includes gene mutations as well as structural and numerical alterations in chromosomes (Eastmond et al.
Definition. A Mutation occurs when a DNA gene is damaged or changed in such a way as to alter the genetic message carried by that gene. A Mutagen is an agent of substance that can bring about a permanent alteration to the physical composition of a DNA gene such that the genetic message is changed. Once the gene has been damaged or changed the mRNA transcribed from that gene will now carry an altered message.