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Early to Bed. Early to bed early to rise makes a man healthy wealthy and wise, is one of the most widely quoted proverbs from Benjamin Franklin's Poor Richard's Almanac. This proverb is seldom disputed however I fail to see the logic behind it.
Expert: Dr. R replied 5 years ago. 30 minutes after a meal in general. However, most men prefer to take it just before going to sleep. If you take it twice a day, I would add once in the am 30 minutes after breakfast. The reason is it can lower your blood pressure a touch and cause light headedness-better to happen just before bed. Food can interfere with it's absorption. Dr. R, Board Certified Urologist.