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What are the symptoms of Hantavirus disease, and how long after infection do they appear? Symptoms usually appear within two to four weeks of infection, but can appear as early as one week or as late as six weeks after infection. Initial symptoms are general and ï¬u-like: fever (101Â° F and above); headache; abdominal, joint, and lower back pain; sometimes nausea and vomiting.
Hantavirus Pulmonary Syndrome (HPS). Severe HPS. Image courtesy D. Loren Ketai, M.D. Hantavirus Pulmonary Syndrome (HPS) is a severe, sometimes fatal, respiratory disease in humans caused by infection with a hantavirus. Anyone who comes into contact with rodents that carry hantavirus is at risk of HPS.Rodent infestation in and around the home remains the primary risk for hantavirus exposure.Even healthy individuals are at risk for HPS infection if exposed to the virus.n fact, in a study of health care workers who were exposed to either patients or specimens infected with related types of hantaviruses (which cause a different disease in humans), none of the workers showed evidence of infection or illness. Hantavirus Pulmonary Syndrome (HPS) Topics.