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Underlying medical conditions that can lead to nausea and fatigue include: 1  acute liver failure. 2  cancer. 3  chronic kidney disease. 4  food allergies. 5  hyperthyroidism.6  hypothyroidism.nderlying medical conditions that can lead to nausea and fatigue include: 1  acute liver failure. 2  cancer. 3  chronic kidney disease. 4  food allergies. 5  hyperthyroidism.
Many things can bring on nausea. Some common causes are seasickness and other motion sicknesses, early pregnancy, intense pain, exposure to chemical toxins, emotional stress (fear), worry (anxiety), gallbladder disease, food poisoning, indigestion, various viruses, and certain smells or odors.