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Underlying medical conditions that can lead to nausea and fatigue include: 1  acute liver failure. 2  cancer. 3  chronic kidney disease. 4  food allergies. 5  hyperthyroidism.6  hypothyroidism.nderlying medical conditions that can lead to nausea and fatigue include: 1  acute liver failure. 2  cancer. 3  chronic kidney disease. 4  food allergies. 5  hyperthyroidism.
Certain cancers and cancer treatments can cause nausea. Your doctor can sometimes predict if your treatment is likely to cause nausea. Medications and other treatments may help you prevent or decrease nausea. Diarrhea or constipation. Cancer and cancer treatment can affect your bowels and cause diarrhea or constipation. Weight loss.