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prostate specific antigen, PSA (noun). a protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer.see more on Definitions.net Â». protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer. see more on Definitions.net Â».
Prostate-specific antigen, or PSA, is a protein produced by cells of the prostate gland. The PSA test measures the level of PSA in a manâs blood.For this test, a blood sample is sent to a laboratory for analysis. The results are usually reported as nanograms of PSA per milliliter (ng/mL) of blood.n addition to prostate cancer, a number of benign (not cancerous) conditions can cause a manâs PSA level to rise. The most frequent benign prostate conditions that cause an elevation in PSA level are prostatitis (inflammation of the prostate) and benign prostatic hyperplasia (BPH) (enlargement of the prostate).