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Underlying medical conditions that can lead to nausea and fatigue include: 1  acute liver failure. 2  cancer. 3  chronic kidney disease. 4  food allergies. 5  hyperthyroidism.6  hypothyroidism.nderlying medical conditions that can lead to nausea and fatigue include: 1  acute liver failure. 2  cancer. 3  chronic kidney disease. 4  food allergies. 5  hyperthyroidism.
Other causes of nausea include side effects from medications, pain, pregnancy and morning sickness, seasickness, viral infection, alcohol toxicity, and disease of the brain, esophagus, stomach, gallbladder, liver, pancreas, and intestine. Medically Reviewed by a Doctor on 4/25/2016.