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Clostridium difficile is a gram-positive, anaerobic, spore-forming bacillus that is responsible for the development of antibiotic-associated diarrhea and colitis. C difficile infection (CDI) commonly manifests as mild to moderate diarrhea, occasionally with abdominal cramping.
A C.Diff Infection is by far the most common cause of diarrhea found in hospital patients. Why Patients Hospital Patients Are Especially Susceptible. Basically, a C.Diff Infection occurs when a bodies preventative bacteria is not strong enough to stop the c.diff from outgrowing the GI tract. C.diff Infection occurs when the c.diff micro-organism grows out of control in the gastronintestinal tract (GI). Ordinarily this kind of micro-organism is harmless and actually helps in the digestion of food and nutrients.