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Mutagenicity is a specific term that refers to a permanent, heritable change in the structure or amount of genetic material of an organism and includes gene mutations as well as structural and numerical alterations in chromosomes (Eastmond et al.
Mutagens that cause base substitutions are corrected by mutagens of the same class (nitrous acid, 2-aminopurine, and 5-bromouracil). Frameshift mutations are corrected by the same class of frameshift mutagens, but not by mutagens that cause base substitutions. X-rays cause major structural changes in chromosomes (deletions, translocations, etc.) and are not corrected by any mutagen, including X-rays.