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From Wikipedia, the free encyclopedia. Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
The hormone gastrin is produced by cells lining gastric glands in the lower region of the stomach (labeled hexagon). Secretion is stimulated (solid arrow) by the presence of peptides and amino acids in the stomach.Caffeine is also a stimulant (solid arrow).he hormone gastrin is produced by cells lining gastric glands in the lower region of the stomach (labeled hexagon). Secretion is stimulated (solid arrow) by the presence of peptides and amino acids in the stomach.