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Most often, colon cancer spreads to the liver, but it can also spread to the ovaries, lungs, or brain. Colon cancer tends to spread to the liver first, because all of the blood from the colon drains to the liver before proceeding to the rest of the body.
A answered. Colon cancer can cause a person to feel tired or weak, lose weight, and have general discomfort in their digestive system and bowel movements. In the later stages of colon cancer, the cancer can spread beyond the rectum into other parts of the body. In stage III colon cancer, the lymph nodes that reside nearby are infected. In the final stage of colon cancer, stage IV, the cancer has spread to other organs, such as the liver or lungs.