During the last decade, the efficacy of arsenic trioxide in both newly diagnosed and relapsed patients with APL 3 has been established. Arsenic trioxide can be used as a single agent and induces complete remissions with only minimal myelosuppression (1) (2, 3, 4, 5) . In one study (2) (1) .Additional studies conducted in the United States confirmed that low doses of arsenic trioxide can induce complete remission in relapsed APL patients.hite arsenic or arsenic trioxide (As 2 O 3) is produced by heating realgar (10) . Arsenic is rarely found in a pure state; rather, it exists in both trivalent and pentavalent oxidation states as a chemically unstable sulfide or oxide, or as a salt of sodium, potassium, or calcium (11) .
More than a few, actually. A big new study of statin use in the real world found that 17 percent of patients taking the pills reported side effects, including muscle pain, nausea, and problems with their liver or nervous system.
WELL-KNOWN SIDE EFFECTS: LIVER AND MUSCLE. The side effects that your doctor will be most familiar with are: 1  Liver: Changes in liver function occur in a small fraction of people; your doctor will probably monitor blood tests to check that your liver continues to function well.2  Muscle: Muscle symptoms are common with statin drugs. Please contact us and let us know about your side effects; the more we know, the more we can help others. 2  Some doctors are not familiar with the evidence that statin drugs or cholesterol drugs can cause problems with memory, pain, irritability, or sleep. 3  You may need to educate them, and we are happy to help.