1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
All types of liver disease above can cause damage to the liver. The advice on this page is specific to alcohol-related liver disease. Alcohol-related liver disease can be prevented if you understand the impact excessive alcohol drinking can have on your liver and take-steps to control the amount you drink. For more information on how alcohol affects your health, read about the short and long-term effects of alcohol in your body.