How to Respond to an Epidemic. Imagine an epidemic so virulent that it is the leading cause of death for children, teens, young adults. It takes 125,000 lives in America alone every year, not to mention causing nearly $80 billion in medical costs.
The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. This can either involve the replication of DNA in living organisms such as prokaryotes and eukaryotes, or that of DNA or RNA in viruses, such as double-stranded RNA viruses.
B. DNA Replication in Bacteria. DNA Replication in Bacteria. In general, DNA is replicated by uncoiling of the helix, strand separation by breaking of the hydrogen bonds between the complementary strands, and synthesis of two new strands by complementary base pairing. Replication begins at a specific site in the DNA called the origin of replication (oriC). DNA replication is bidirectional from the origin of replication. To begin DNA replication, unwinding enzymes called DNA helicases cause short segments of the two parent DNA strands to unwind and separate from one another at the origin of replication to form two Y-shaped replication forks. These replication forks are the actual site of DNA copying (see Fig. 4).