Speciï¬cally, the sva package contains functions. for the identifying and building surrogate variables for. high-dimensional data sets. Surrogate variables are covariates. constructed directly from high-dimensional data (like gene. expression/RNA sequencing/methylation/brain imaging data) that. can be used in subsequent analyses to adjust for unknown, unmodeled, or latent sources of noise. The sva package can be.
Princess of Wales Diana Biography. Lady Diana Frances Spencer married Prince Charles (1948â) in 1981 and became Princess of Wales. Retaining her title and her popularity after the royal couple divorced in 1996, Diana continued her charitable work. She died in a tragic car accident in 1997.
The late Diana, Princess of Wales was born The Honourable Diana Frances Spencer on 1 July 1961 in Norfolk. She received the style Lady Diana Spencer in 1975, when her father inherited his Earldom. Lady Diana Spencer married The Prince of Wales at St Paul's Cathedral in London on 29 July 1981. During her marriage the Princess undertook a wide range of royal duties. Family was very important to the Princess, who had two sons: Prince William and Prince Henry (Harry).