Type 4 Waardenburg syndrome (also called Waardenburg-Shah syndrome) is characterized by symptoms of Hirschsprung's disease in addition to the classic features of hearing loss and pigmentation abnormalities.
[Effects of a vitamin B complex on functional recovery after nerve injury (author's transl)]. Hasegawa K, Mikuni N, Sakai Y. Functional recovery after nerve crushing was investigated in the following manner: Under pentobarbital anesthesia the sciatic nerve of the rat was crushed at the level of the hip (proximal crush) or the thigh (distal crush).
Vitamin B6 may provide some relief from hot flashes in doses of 50 milligrams by mouth, once a day. It is important not to exceed the recommended dosage. Taking more than 100 milligrams of vitamin B6 daily may cause irreversible nerve damage.