Speciï¬cally, the sva package contains functions. for the identifying and building surrogate variables for. high-dimensional data sets. Surrogate variables are covariates. constructed directly from high-dimensional data (like gene. expression/RNA sequencing/methylation/brain imaging data) that. can be used in subsequent analyses to adjust for unknown, unmodeled, or latent sources of noise. The sva package can be.
Princess of Wales Diana Biography. Lady Diana Frances Spencer married Prince Charles (1948â) in 1981 and became Princess of Wales. Retaining her title and her popularity after the royal couple divorced in 1996, Diana continued her charitable work. She died in a tragic car accident in 1997.
On February 24, 1981 the engagement of Charles, Prince of Wales and Lady Diana Spencer was announced at Buckingham Palace. On July 29, 1981 Charles married Princess Diana. The fairy-tale wedding took place at St. Paul's Cathedral. Eleven months later on June 21, 1982 Prince William Windsor was born.wo years later their second son Prince Harry Windsor was born September 15, 1984. Diana said that during the months before was his birth, she and Charles were closer then they ever had been before, but after the birth of Harry the marriage went badly wrong.