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For most drugs, the window of detection in oral fluid is typically 24-48 hours. 4. How soon after use can a drug be detected in saliva? Oral fluid testing can detect drugs in the saliva roughly 30-60 minutes after ingestion.
1 Blood testsâ effective ranges will vary based on the half-life of the drug but are generally sensitive for about one to three days.[1] Marijuana edibles will linger longer, for up to seven days.  Saliva tests range depending on the drug, but most can detect drugs used in the last 12 hours to three days.