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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
Diabetes frequent urination problems are often most noticeable at night. Going to the toilet a lot (especially at night) can make you feel tired, but both the fatigue and frequent urination can be one of type 2 diabetes early symptoms. What is considered normal for urinary frequency?