Speciï¬cally, the sva package contains functions. for the identifying and building surrogate variables for. high-dimensional data sets. Surrogate variables are covariates. constructed directly from high-dimensional data (like gene. expression/RNA sequencing/methylation/brain imaging data) that. can be used in subsequent analyses to adjust for unknown, unmodeled, or latent sources of noise. The sva package can be.
Princess of Wales Diana Biography. Lady Diana Frances Spencer married Prince Charles (1948â) in 1981 and became Princess of Wales. Retaining her title and her popularity after the royal couple divorced in 1996, Diana continued her charitable work. She died in a tragic car accident in 1997.
How they met. Prince Charles first met his future bride Diana Spencer at a garden party in 1977 through her older sister Sarah, whom he was dating at the time. There had been much speculation about the Prince's love life, and Diana is said to have been in awe of the heir-to-the-throne upon their first introduction. After much speculation in the press, the announcement came from Buckingham Palace on February 24, 1981, that Charles and Diana were engaged to be married.