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Dosage of Keflex for Bacterial Infections. The recommended dose of Keflex for most types of bacterial infections is 250 mg to 1000 mg, taken four times a day for 7 to 14 days. For chronic or more serious infections, your healthcare provider may continue treatment for a longer period of time.he recommended dosage of Keflex for the prevention of bacterial endocarditis in children is 50 mg per kilogram of body weight, up to a maximum of 2000 mg, taken one hour before a surgical procedure is performed.
In pediatric patients, a total daily dosage of 25 to 50 mg per kg (approximately 10 to 20 mg per pound) of body weight, divided into 3 or 4 equal doses, is effective for most mild to moderately severe infections. Total daily dosage may be increased to 100 mg per kg (45 mg per pound) of body weight for severe infections. Since safety for use in premature infants and in neonates has not been established, the use of Cefazolin for injection in these patients is not recommended.