1 In January of 1857 the first performances of The Frozen Deep are given. Dickens plays the role of Richard Wardour. This play gives Dickens the idea for A Tale of Two Cities.  In August of 1857 Dickens meets Ellen Ternan, an actress hired to act in benefit performances of The Frozen Deep.
If you overload your liver (drink too much at one time), the excess alcohol will end up circulating in your bloodstream affecting your brain, heart and other tissues resulting in you becoming increasingly intoxicated.
Each time your liver filters alcohol, some of the liver cells die. The liver can develop new cells, but prolonged alcohol misuse (drinking too much) over many years can reduce your liverâs ability to regenerate.rinking a large amount of alcohol, even for just a few days, can lead to a build-up of fats in the liver. This is called alcoholic fatty liver disease, and is the first stage of ARLD.