Exploring the Southern Constellations. September 2008 : In the summer of 1865, noted American newspaperman and politician Horace Greeley penned, in an editorial, an admonishment to young civil servants in Washington DC. Greeley urged those who complained of low pay grades in the Capitol area to âGo west, young man!â.
When your muscles can't get enough oxygen during a short burst of exercise, they start to make use of a pathway called lactic acid fermentation, which generates a small three-carbon compound called lactic acid or lactate as a byproduct of glucose breakdown.
The lactic acidosis of exercise has been a classic explanation of the biochemistry of acidosis for more than 80 years. This belief has led to the interpretation that lactate production causes acidosis and, in turn, that increased lactate production is one of the several causes of muscle fatigue during intense exercise.This review presents clear evidence that there is no biochemical support for lactate production causing acidosis.his belief has led to the interpretation that lactate production causes acidosis and, in turn, that increased lactate production is one of the several causes of muscle fatigue during intense exercise. This review presents clear evidence that there is no biochemical support for lactate production causing acidosis.