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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
The subjects in that study did not have a history of heavy cannabis use, so the effect on sleep may have to do with tolerance. One effect on sleep seems fairly consistent: THC reduces the amount of time a person spends in rapid eye movement sleep, the phase of sleep where most dreaming occurs. 7. Reduced pain