State in writing that the LETTER OF REPRIMAND is being made a part of the employeeâs personnel file. Specify that future disciplinary action will be taken unless there is improvement and specify the measurements for satisfactory performance. Please note that in effect this is a warning as well as a reprimand.
There are thousands of single-gene diseases including achondroplasia, cystic fibrosis, hemophilia, Huntington disease, muscular dystrophy, and sickle cell disease.Single-gene diseases usually follow simple Mendelian patterns of inheritance -- autosomal dominant, an autosomal recessive, or an X-linked.Single gene diseases are as opposed to polygenic diseases which are caused by a combination of two or more genes.ingle-gene diseases usually follow simple Mendelian patterns of inheritance -- autosomal dominant, an autosomal recessive, or an X-linked. Single gene diseases are as opposed to polygenic diseases which are caused by a combination of two or more genes.
1 Only a few human diseases are triggered by a single gene working by itself. 2  In most cases, a disease results from the actions of many genes. 3  An example of a single-gene disorder is Huntington's disease, which was discussed in the last chapter. 4  One error in one gene leads to the fatal health problems of HD. Only a few human diseases are triggered by a single gene working by itself. 2  In most cases, a disease results from the actions of many genes. 3  An example of a single-gene disorder is Huntington's disease, which was discussed in the last chapter. 4  One error in one gene leads to the fatal health problems of HD.