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Progesterone. Print | Email article to a friend | Last updated: January 14, 2015. Progesterone is a hormone released by the corpus luteum in the ovary. It plays important roles in the menstrual cycle and in maintaining the early stages of pregnancy. It may also be involved in the growth of certain cancers.
Progesterone is made primarily by the ovaries. The adrenal glands, peripheral nerves, and brain cells produce lesser amounts. Progesterone ensures the development and function of the breasts and female reproductive tract. In the brain, progesterone binds to certain receptors to exert a calming, sedating effect.n women, various sex hormones like estrogen, progesterone, testosterone, and other hormones like cortisol, and DHEA, exert powerful effects throughout life.