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activation energy. activation energy, in chemistry, minimum energy needed to cause a chemical reaction. A chemical reaction between two substances occurs only when an atom, ion, or molecule of one collides with an atom, ion, or molecule of the other.
Exergonic reactions have a net release of energy, but they still require a small amount of energy input before they can proceed with their energy-releasing steps. This small amount of energy input necessary for all chemical reactions to occur is called the activation energy (or free energy of activation) and is abbreviated E A. Activation energy: Activation energy is the energy required for a reaction to proceed; it is lower if the reaction is catalyzed.