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Posts. 148. elguapo, It comes with that warning because diphenhydramine, the active ingredient in Unisom, can make urination more difficult. A guy with an enlarged prostate is already going to have difficulty urinating and diphenhydramine would just add to the problem.
Many males occasionally, wake up in the middle of the night with wet sheets and underpants. When this happens, they are probably experiencing something called nocturnal emissions, or wet dreams.. A nocturnal emission is an involuntary ejaculation of semen that occurs during sleep.