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metabolism. 1. biotransformation. 2. the sum of the physical and chemical processes by which living organized substance is built up and maintained (anabolism), and by which large molecules are broken down into smaller molecules to make energy available to the organism (catabolism).
metabolism [(muh-tab-uh-liz-uhm)] The total of the chemical reactions that maintain the life of a living thing. Note: In humans, metabolism is related to the intake and use of food; persons with a high metabolism can eat more without gaining weight.