Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
Pakistan's 2nd most populous city, Lahore, is only about half the size, with just 6.3 million people, but is still the world's 15th most populous city. Pakistan has six additional cities that have passed the one million population mark.
For other uses, see Karachi (disambiguation). Karachi (Urdu: Ú©Ø±Ø§ÚÛâ; Sindhi: ÚªØ±Ø§ÚÙâ; ALA-LC: KarÄcÄ«, IPA: [kÉËrÉËËtÊi]) is the capital of Sindh, and is the largest and most populous city in Pakistan, as well as the 7th largest in the world and the world's second most populous city proper.