The toxic effect is related linearly through a relatively large range of body weights, to the body weight of the victim, and, The mechanism of toxicity is the same for âsimilar animalsâ, i. e. one may conduct toxicity tests on say rats or mice and apply the LD50 data to human, since both are mammals.
For moderate menstrual cramps, the nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen [Advil, Motrin, Nuprin, etc.] or naproxen [Aleve, Anaprox, Naprosyn, Naprelan]) are often helpful.
Menstrual cramps and PMS medication facts. 1  Menstrual cramps that occur in the absence of a known abnormality or cause are medically referred to as primary dysmenorrhea.  Non-drug treatments for menstrual cramps include adequate rest and sleep, regular exercise (especially walking), and smoking cessation.