Examples of APPLICATION. 1  Our loan application has been approved. 2  Anyone interested in running for office must file an application by August 1st. 3  If you'd like to be considered for the job, please send us a letter of application that gives your experience and qualifications.xamples of APPLICATION. 1  Our loan application has been approved. 2  Anyone interested in running for office must file an application by August 1st. 3  If you'd like to be considered for the job, please send us a letter of application that gives your experience and qualifications.
brain reward pathways The most important reward pathway in brain is the mesolimbic dopamine system. This circuit (VTA-NAc) is a key detector of a rewarding stimulus. Under normal conditions, the circuit controls an individual's responses to natural rewards, such as food, sex, and social interactions, and is therefore an important determinant of motivation and incentive drive.
The mesolimbic pathway, which originates in the middle of the brain and branches to various places like the cerebral cortex, is the most important reward pathway in the brain. One of the mesolimbicâs stops is the nucleus accumbens. Increased dopamine in the nucleus accumbens signals feedback for predicting rewards. Your brain recognizes that something important â good or bad â is about to happen, thus triggering motivation to do something.