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Possible causes of bladder outlet obstruction might include: 1  Enlarged prostate, also known as benign prostatic hyperplasia (BPH) â this is the most common cause of bladder outlet obstruction in men. 2  Scarring of the urinary channel (urethra) or bladder neck, as a result of injury or surgery.
Overactive Bladder Causes. The urinary bladder is comprised of nerves, muscles, and connective tissue. The most important muscle in the bladder is the detrusor muscle. In normal circumstances, when the bladder fills with urine, it can stretch to hold the urine.When the volume in the bladder reaches close to 300 cc, the stretch in the wall of the bladder can trigger a nerve response to initiate urination (micturition).he urinary bladder is comprised of nerves, muscles, and connective tissue. The most important muscle in the bladder is the detrusor muscle.