Qualitative and quantitative factor deficiencies can affect the function of the coagulation pathways. Factor V and factor II (prothrombin) mutations are examples of qualitative deficiencies and are the most common inherited predisposing factors for blood clots.
Definition. A comma splice is a run on sentence, where two or more independent clauses are 'spliced' or split by a comma. A comma splice is considered a significant English error.
run-on sentence(Noun) an ungrammatical sentence in which two independent clauses that should be joined by either a semicolon or a conjunction or should be separate sentences are written as a single sentence, the clauses often being separated by a comma.