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The dosage range for cephalexin (KeflexÂ®) is most often 22 to 33 mg/kg. Great Danes are big dogs as you know (weight range can be 110 to 160 pounds). Let's say your dog weighs a modest 110 pounds. They would be roughly 55 kg. 55 kg x 22 mg/kg = 1210 mg or if they used the 33 mg/kg = 1815 mg.
When you give your dogs aspirin it is generally safe to give them one baby aspirin per 35 pounds of body weight. Do not give your dog Tylenol , unless prescribed and supervised by a veterinarian, as it has been reported to kill a dog or a cat in a matter of minutes. You should also refrain from giving your dog Ibuprofen (also known as Advil) for prolonged periods of time as it can cause not only stomach upset but also ulcers.