The FDA based its decision to approve Linzess on the results of two randomized, double-blind, placebo-controlled clinical studies. 90% of the patients in the trials were female. In the open-label, long-term trials, 2147 patients with IBS-C received 290 mcg of Linzess daily for up to 18 months.
1 Everyone has one of four blood types â A, B, AB, or O â which is inherited from your parents. 2  Your blood type is determined by the presence or absence of two antigens â A and B â on the surface of red blood cells.A third antigen, called Rh factor, will either be present or absent. Antigens are substances that may trigger an immune response, causing your body to launch an attack if it believes they are foreign.hile all blood is similar in its components (such as containing red cells, platelets, and plasma), it also has important characteristics that make it unique. Your blood type is determined by the presence or absence of two antigens â A and B â on the surface of red blood cells.
Blood type (or blood group) is determined, in part, by the ABO blood group antigens present on red blood cells. A blood type (also called a blood group) is a classification of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells (RBCs). Blood group A individuals have the A antigen on the surface of their RBCs, and blood serum containing IgM antibodies against the B antigen. 2  Therefore, a group A individual can receive blood only from individuals of groups A or O (with A being preferable), and can donate blood to individuals with type A or AB.