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Possible causes of bladder outlet obstruction might include: 1  Enlarged prostate, also known as benign prostatic hyperplasia (BPH) â this is the most common cause of bladder outlet obstruction in men. 2  Scarring of the urinary channel (urethra) or bladder neck, as a result of injury or surgery.
The most common cause for this blockage is a kidney stone, but scarring and blood clots can also cause acute unilateral obstructive uropathy. A blocked ureter can cause urine to go back up into the kidney, which causes swelling. This backflow of urine is known as vesicoureteric reflux (VUR).