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metabolism. 1. biotransformation. 2. the sum of the physical and chemical processes by which living organized substance is built up and maintained (anabolism), and by which large molecules are broken down into smaller molecules to make energy available to the organism (catabolism).
metabolism. 1  Biology, Physiology. the sum of the physical and chemical processes in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. 2  any basic process of organic functioning or operating: changes in the country's economic metabolism.