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Peyronie's disease is penis problem caused by scar tissue, called plaque, that forms inside the penis. It can make the penis to bend upward or to the side. Most men with Peyronie's disease can still have sex. But for some, itâs difficult or painful.
Certain health issues, such as high blood sugar, tobacco use, or past pelvic trauma, may also lead to wound healing problems, and may help cause Peyronie's disease. Stages of Peyronie's Disease. Peyronie's disease is often split into 2 stages: the acute phase and the chronic phase. During both phases, the bent/curved penis may cause problems with sex. You also may have ED. Acute Phase: The acute phase lasts for 6 to 18 months.