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There are four key causes of low creatinine: low muscle mass; liver problems; diet; pregnancy or illness; Low muscle mass. Levels of creatinine are often linked with muscle mass or the amount of muscle in the body, which can decrease with age or illness.
A decrease in the serum albumin level may occur with severe disease of the kidney. Other conditions such as liver disease, malnutrition, and extensive burns may result in serious decrease of plasma proteins. albumin-globulin ratio the ratio of albumin to globulin in blood serum, plasma, or urine. decrease in the serum albumin level may occur with severe disease of the kidney. Other conditions such as liver disease, malnutrition, and extensive burns may result in serious decrease of plasma proteins. albumin-globulin ratio the ratio of albumin to globulin in blood serum, plasma, or urine.