Qualitative and quantitative factor deficiencies can affect the function of the coagulation pathways. Factor V and factor II (prothrombin) mutations are examples of qualitative deficiencies and are the most common inherited predisposing factors for blood clots.
Definition. A comma splice is a run on sentence, where two or more independent clauses are 'spliced' or split by a comma. A comma splice is considered a significant English error.
When you are fixing a comma splice or fused sentence, subordinate conjunctions are the most tricky to use. There are two reasons that subordinate conjunctions are tricky: 1) there are many subordinate conjunctions to choose from, and 2) you must use the right punctuation.