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Definition of gastrointestinal tract. medical. : the part of the digestive system that consists of the stomach and intestines.
Gastrointestinal motility refers to the contraction of the smooth muscles of the gastrointestinal tract. 1  The gastrointestinal tract is commonly divided into 5 parts: the mouth, esophagus, stomach, small intestine, and large intestine (colon). These parts are separated from each other by special muscles called sphincters which normally stay tightly closed and which regulate themovement of food and food residues from one part to another.