Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
The enormous population of 23.5 million (23,500,000) is also due to the fact that Karachi is the main business center of, almost, all the corporations in Pakistan. Having population density of 6,663/km2, it is also a main hub of higher education in Muslim world. See Also; 10 Most Dangerous Cities in The World.
Pakistan's population is growing by around 1.8pc a year but the economy has failed to keep pace with the population growth. At this pace and if the population growth does not slow down, it will outpace Indonesia by 2030 as the country with the largest Muslim population.