Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
The enormous population of 23.5 million (23,500,000) is also due to the fact that Karachi is the main business center of, almost, all the corporations in Pakistan. Having population density of 6,663/km2, it is also a main hub of higher education in Muslim world. See Also; 10 Most Dangerous Cities in The World.
Mirpur Khas (Urdu : / Sindhi: ÙÛØ±Ù¾ÙØ± Ø®Ø§Øµ; meaning the land of the most high mirs) is a city in the province of Sindh in Pakistan. It is the fourth largest city in the province with an estimated population of 124,371 (1981). It is the capital of Mirpur Khas District.