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Most of the time, no apparent cause for night leg cramps can be identified. In general, night leg cramps are likely to be related to muscle fatigue and nerve problems. The risk of having night leg cramps increases with age. Pregnant women also have a higher likelihood of having night leg cramps. Several conditions, such as kidney failure and diabetic nerve damage, are known to cause night leg cramps. But if you have one of these, you're most likely aware of it and have symptoms other than night leg cramps.
Causes. Most of the time, night leg cramps occur for no known reason, and they're usually harmless. In general, night leg cramps are likely to be related to muscle fatigue and nerve problems. The risk of having night leg cramps increases with age.Pregnant women also have a higher likelihood of experiencing night leg cramps.estless legs syndrome (RLS) is sometimes confused with night leg cramps, but it's a separate condition. In general, pain is not a main feature of RLS, but RLS could be the cause of night leg cramps. Other conditions that may sometimes be associated with night leg cramps may include: Structural disorders.