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The dosage range for cephalexin (KeflexÂ®) is most often 22 to 33 mg/kg. Great Danes are big dogs as you know (weight range can be 110 to 160 pounds). Let's say your dog weighs a modest 110 pounds. They would be roughly 55 kg. 55 kg x 22 mg/kg = 1210 mg or if they used the 33 mg/kg = 1815 mg.
Stop Puppy Mills Website. Cephalexin is an antibiotic used in dogs. It is most commonly prescribed after a surgery or to treat a bacterial infection, dermatological problems and urinary tract infections. Cephalexin for use in dogs is similar to the use of penicillin in humans.