Qualitative and quantitative factor deficiencies can affect the function of the coagulation pathways. Factor V and factor II (prothrombin) mutations are examples of qualitative deficiencies and are the most common inherited predisposing factors for blood clots.
Definition. A comma splice is a run on sentence, where two or more independent clauses are 'spliced' or split by a comma. A comma splice is considered a significant English error.
Comma Splices. Comma splices are similar to run-on sentences because they also incorrectly connect independent clauses. A comma splice occurs when two independent clauses are connected with only a comma. As with a run-on sentence, there are a few different ways to correct a comma splice. Consider the following sentence and the revised versions that follow it.