Qualitative and quantitative factor deficiencies can affect the function of the coagulation pathways. Factor V and factor II (prothrombin) mutations are examples of qualitative deficiencies and are the most common inherited predisposing factors for blood clots.
Definition. A comma splice is a run on sentence, where two or more independent clauses are 'spliced' or split by a comma. A comma splice is considered a significant English error.
Comma Splice A comma splice is the use of a comma between two independent clauses. You can usually fix the error by changing the comma to a. period and therefore making the two clauses into two separate sentences, by changing the comma to a semicolon, or by making one clause.