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The dosage range for cephalexin (KeflexÂ®) is most often 22 to 33 mg/kg. Great Danes are big dogs as you know (weight range can be 110 to 160 pounds). Let's say your dog weighs a modest 110 pounds. They would be roughly 55 kg. 55 kg x 22 mg/kg = 1210 mg or if they used the 33 mg/kg = 1815 mg.
If you choose to give your dog charcoal, do not give it to your dog for more then two or three days at a time because it not only helps to detoxify noxious gases, but it also can absorb nutrients as well, robbing your dog of vitamins and minerals. Ask your vet before you give your dog charcoal products.