Iatrogenic Cushing Syndrome. Author: Ha Cam Thuy Nguyen, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP more... Background. Cushing syndrome, first described by Harvey in 1912, refers to signs and symptoms caused by excess free plasma glucocorticoids. Excess glucocorticoids can be from increased endogenous production or prolonged exposure to exogenous use of glucocorticoid products.
As is apparent from the above discussion, a drug target is a key molecule involved in a particular metabolic or signal transduction pathway that is specific to a disease condition or a specific disease. However, the term âdrug targetâ itself has several limitations and is debated within the pharmaceutical industry.n this respect, several points should be kept in mind. First, a drug target is a relative concept. For starters, a drug target is, just like other biomolecules, also a biomolecule involved in a transduction pathway. The difference between the two is only in their location and role in the transduction pathway.
A drug is any substance that alters the central nervous system, brain chemistry or bodily functions. There is no single definition since there are different meanings of the word drug, with regard to medicine, government and street usage. Dictionary.com defines a drug as a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well-being.. Medicinal drugs may be prescribed by a doctor for a limited time frame or for use on a regular basis for chronic condition. Recreational drugs or street drugs are drugs that target the central nervous system and brain chemistry. They are used specifically to alter perception, mood and behavior. Many recreational drugs lead to abuse and dependency.