Inflammatory bowel disease (IBD) involves inflammation of the intestines and is a chronic (long-lasting) illness. The two major types of IBD are ulcerative colitis and Crohn's disease. Ulcerative colitis affects the lining of the large intestine (colon) and/or the rectum.
Definition of comb binding. : mechanical binding (as of pamphlets) in which split rings of plastic or metal are passed through slots at the gutter margin.
In allosteric enzymes, the binding of one substrate to an active site can alter the properties of the other active sites on the molecule -- facilitates cooperative binding, which is a sigmoidal plot.