Qualitative and quantitative factor deficiencies can affect the function of the coagulation pathways. Factor V and factor II (prothrombin) mutations are examples of qualitative deficiencies and are the most common inherited predisposing factors for blood clots.
Definition. A comma splice is a run on sentence, where two or more independent clauses are 'spliced' or split by a comma. A comma splice is considered a significant English error.
Know the solution. To fix a comma splice or fused sentence, use one of the four strategies below. Because comma splices and fused sentences contain two main clauses, you can always add a period [a full stop] at the end of the first clause and then begin the second one with a capital letter. Take a look at the fused sentence below: