Qualitative and quantitative factor deficiencies can affect the function of the coagulation pathways. Factor V and factor II (prothrombin) mutations are examples of qualitative deficiencies and are the most common inherited predisposing factors for blood clots.
Definition. A comma splice is a run on sentence, where two or more independent clauses are 'spliced' or split by a comma. A comma splice is considered a significant English error.
Six Ways to Eliminate Fused Sentences and Comma Splices. 1  It was close to fall. The trees were losing their leaves. 2  It was close to fall; the trees were losing their leaves. 3  It was close to fall, so the trees were beginning to lose their leaves.  It was the time of year when trees begin to lose their leaves.