Orange juice is the liquid extract of the fruit of the orange tree, extracted by squeezing oranges. It comes in several different varieties, including blood orange. In American English, the beverage name may be abbreviated as OJ.
Summary Summary. Listen. Myelofibrosis is a disorder of the bone marrow, in which the marrow is replaced by fibrous (scar) tissue. When the bone marrow is scarred, it cannot make enough blood cells. This leads to anemia, weakness, fatigue, and often, swelling of the liver and spleen.
This will cause scarring in the bone marrow that is very extensive and leads to anemia that is severe, fatigue, and weakness as well as in some cases an enlarged liver and spleen. Myelofibrosis is actually a type of chronic leukemia â cancer that upsets the tissues that are blood-forming in the body. This disorder can happen on its own (primary myelofibrosis) or it may occur because of other disorders of the bone marrow (secondary myelofibrosis). Numerous individuals with myelofibrosis progressively get worse and certain ones can eventually develop a much more serious form of leukemia.