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Beyond these basic, universal features, eukaryotic genomes vary dramatically in terms of size and gene counts. Even so, genome size and the number of genes present in an organism reveal little about that organism's complexity (Figure 1).ne pg is equivalent to approximately 1 billion base pairs.) Therefore, genome size is clearly not an indicator of the genomic or biological complexity of an organism. Otherwise, humans would have at least as much DNA as the marbled lungfish, although probably much more.
The number of genes in an organismâs genome (the entire set of chromosomes) varies significantly between species. For example, whereas the human genome contains an estimated 20,000 to 25,000 genes, the genome of the bacterium Escherichia coli O157:H7 houses precisely 5,416 genes.