Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
The enormous population of 23.5 million (23,500,000) is also due to the fact that Karachi is the main business center of, almost, all the corporations in Pakistan. Having population density of 6,663/km2, it is also a main hub of higher education in Muslim world. See Also; 10 Most Dangerous Cities in The World.
1 List of cities of Punjab, Pakistan by area. 2  List of most populous metropolitan areas in Pakistan. 3  List of most populous cities in Pakistan.  4 List of Tehsils/Talukas with respect to their Districts (PDF). Statistics Division, Government of Pakistan. - Updated July 2014.  List of Province and all Districts of Pakistan.