Examples of APPLICATION. 1  Our loan application has been approved. 2  Anyone interested in running for office must file an application by August 1st. 3  If you'd like to be considered for the job, please send us a letter of application that gives your experience and qualifications.xamples of APPLICATION. 1  Our loan application has been approved. 2  Anyone interested in running for office must file an application by August 1st. 3  If you'd like to be considered for the job, please send us a letter of application that gives your experience and qualifications.
brain reward pathways The most important reward pathway in brain is the mesolimbic dopamine system. This circuit (VTA-NAc) is a key detector of a rewarding stimulus. Under normal conditions, the circuit controls an individual's responses to natural rewards, such as food, sex, and social interactions, and is therefore an important determinant of motivation and incentive drive.
Dopamine receptors in the area of the nucleus accumbens are part of the brain's reward system. Dopamine motivates us toward pleasure. It is associated with the anticipation of something the brain has identified as valuable, rewarding, and special to us. That something can be anything, including a person or a drug.