Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
The enormous population of 23.5 million (23,500,000) is also due to the fact that Karachi is the main business center of, almost, all the corporations in Pakistan. Having population density of 6,663/km2, it is also a main hub of higher education in Muslim world. See Also; 10 Most Dangerous Cities in The World.
The climate of Karachi (Pakistan) Karachi is located in the southern part of Pakistan on the Arabian Sea in the province of Sindh of which it also is the capital. With a population of 20 million in the city itself and a population of 25 million in the urban areas Karachi is the largest city in Pakistan.