Airway hyperreactivity is defined as the exaggerated decrease in airflow induced by a standard methacholine challenge test. Chronic asthma requires the regular use of medication to allow the individual to perform the preponderance of military duties.
Generally taken every 6 to 8 hours, the maximum dose of NSAIDs per day is 2400 mg which is 12 over-the-counter tablets. Liver-safe: Ibuprofen and other NSAIDS rarely affect the liver. Unlike acetaminophen (Tylenol) most NSAIDs are absorbed completely and have negligible first-pass hepatic (liver) metabolism. In other words, the way NSAIDS are metabolized makes liver toxicity (hepatotoxicity) very rare.
NSAIDS and ACE-inhibitors. The concomitant use of NSAIDs and ACE inhibitor (ACEI) has been associated with reducing the anti-hypertensive effects of the ACEI, as well as carrying the potential to inflict acute renal damage. The presumed mechanism of these effects on the kidneys and blood pressure stem from NSAIDs affect on prostaglandins (PG). These effects are typically not seen in normotensive patients or those with normal renal function, but occur more in patients with kidney or blood pressure pathologies.