The FDA based its decision to approve Linzess on the results of two randomized, double-blind, placebo-controlled clinical studies. 90% of the patients in the trials were female. In the open-label, long-term trials, 2147 patients with IBS-C received 290 mcg of Linzess daily for up to 18 months.
1 Everyone has one of four blood types â A, B, AB, or O â which is inherited from your parents. 2  Your blood type is determined by the presence or absence of two antigens â A and B â on the surface of red blood cells.A third antigen, called Rh factor, will either be present or absent. Antigens are substances that may trigger an immune response, causing your body to launch an attack if it believes they are foreign.hile all blood is similar in its components (such as containing red cells, platelets, and plasma), it also has important characteristics that make it unique. Your blood type is determined by the presence or absence of two antigens â A and B â on the surface of red blood cells.
There are eight recognized blood types, they are A, B, AB and O Positives (Rh+) and their negative (Rh-) counterparts; A-, B-, AB- and O-. First, we will see how our individual Blood Type Letter is directly determined by the blood types of both of our parents. Next, we will see how the Rh Factor we inherit then fits in, to create the other four (Rh-) negative blood types. We all have 1 Blood Type, but we all carry 2 individual blood type letters. The Inheritance Rule says that each parent must give one of their blood type letters to each of their children. As a result, we get our blood type directly from both of our parents! Want to learn more? Visit the Blood Types and Rh-Negative 101 page.