Smallpox Causes. Variola (the virus that causes smallpox) is a member of the orthopoxvirus genus, which also includes viruses that cause cowpox, monkeypox, orf, and molluscum contagiosum.Poxviruses are the largest animal viruses, visible with a light microscope.urvivors of smallpox often have severely deformed skin from the pustules. 1  Types: Variola major, or smallpox, has a death rate of 30%. 2  Variola minor, or alastrim, is a milder form of the virus with a death rate of 1%. 3  Four types of variola exist: classic, hemorrhagic, malignant, and modified.
This means that even when condoms are used properly, syphilis can still be spread if the sore is located in an area not covered by the condom. Because sores can be located on the lips and mouth as well as the external genitals, vagina, anus, and rectum, there are many possibilities for transmission. [5].
The non-itchy body rash that develops during the second stage of syphilis can show up on the palms of your hands and soles of your feet, all over your body, or in just a few places. You could also be infected with syphilis and have very mild symptoms or none at all. Example of a primary syphilis sore. syphilis infection is called an âearlyâ case if a patient has been infected for a year or less, such as during the primary or secondary stages of syphilis. People who have âearlyâ syphilis infections can more easily spread the infection to their sex partners.