1.) lipid peroxidation - destruction of polyunsat fats -> membrane damage and increased permeability. 2.) attacking critical proteins that affect ion pumps and transport mechanisms. 3.) fragmenting DNA - causing decreased protein synthesis. 4.) damaging mitochondria - causing the liberation of calcium into the cytosol.
Baby Aspirin May Be Best for Heart. May 8, 2007 -- Baby aspirin may be the best aspirin dose for heart health, according to a new research review. A single pill of baby aspirin contains 81 milligrams of aspirin. That's about a quarter of the 325-milligram dose in an adult aspirin pill. The new research review states that in the U.S., the most commonly prescribed aspirin dose for heart health is 81 milligrams per day. The review shows that aspirin doses greater than 81 milligrams per day haven't been proven better than baby aspirin for the heart and may increase the chances of stomach bleeding.
Use of high-dose aspirin for long periods in pregnancy also increases the risk of bleeding in the brain of premature infants. If you need to take aspirin during your third trimester of pregnancy, your health care provider will likely closely monitor you and your baby.