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Herbs to Help Calm an Overactive Dog. Herbs are packed with vitamins, minerals, protein, carbohydrates and fat; they play a key role in your dog's overall well-being and nutrition. Herbs known for their calming properties include valerian, lemon balm, Roman chamomile, lavender, oat and skullcap.
When used continuously, they create a physical dependence. Benzodiazepines commonly used with dogs include alprazolam (Xanax), clonazepam (Klonopin), and diazepam (Valium). These drugs are used to treat anxiety, noise phobias (including thunder phobia), panic attacks, and separation anxiety. They should be used with caution in fear-aggressive dogs, as they may lower fear-based inhibition and increase the likelihood of the dog biting.