Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
The enormous population of 23.5 million (23,500,000) is also due to the fact that Karachi is the main business center of, almost, all the corporations in Pakistan. Having population density of 6,663/km2, it is also a main hub of higher education in Muslim world. See Also; 10 Most Dangerous Cities in The World.
Rawalpindi is in Pakistan. It is a bustling town strategically located between the Punjab and Azad Kashmir. It has a strong colonial influence and possesses a large military cantonment with the headquarters of the Pakistan Army. It is the sister city of Islamabad, and is essentially the older sister of Islamabad.