Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
Pakistan's 2nd most populous city, Lahore, is only about half the size, with just 6.3 million people, but is still the world's 15th most populous city. Pakistan has six additional cities that have passed the one million population mark.
The city is the political seat of Pakistan and is administered by Capital Development Authority (CDA). Islamabad is located in the Pothohar Plateau in the northeastern part of the country, between Rawalpindi District and the Margalla Hills National Park to the north.