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Penile Discharge Fact Sheet Save this for later. Table of Contents. Penile discharge is the abnormal loss of fluid that is not urine or semen from the urethra at the tip of the penis. It is commonly the sign of a sexually transmitted disease (STD), and requires prompt and accurate diagnosis and treatment.
Other causes include: 1  Cervical cancer - this is rare, but occasionally it is the cause of an abnormal discharge. 2  Cervicitis - swelling of the cervix; this is often caused by some sexually transmitted infection. 3  Chlamydia. Genital warts. 4  Gonorrhea. HPV infection.  Pelvic inflammatory disease (PID)