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Reactive thrombocytosis, also known as secondary thrombocytosis, is the most common cause of elevated platelets. This disorder occurs in response to other diseases or conditions. These may include chronic inflammatory conditions, acute infection, some anemias, cancer, and other blood disorders.
What are some causes of an elevated platelet count? Platelets help blood clot, according to the Seattle Cancer Care Alliance. There are normally 150,000 to 450,000 platelets per microliter of blood. However, when the count climbs toward 1 million, the patient usually has reactive, or secondary, thrombocytosis.