Neither of these things are guaranteed to happen if you get the flu vaccine when you are sick, but they are possibilities. If you have just a mild illness, there is no reason to wait to get vaccinated.
Early in the day, let roast stand at room temperature at least 1 hour before cooking. Preheat oven to 375 degrees. Rub meat ... the outside and rare in the middle. Meat will be very brown ... stand at room temperature for at least one hour.
3. Heat the oven to 500 degrees for a raw roast, 375 for a pre-browned one. 4. Place the roasting pan in the oven; cook for 10 minutes, then lower the heat to 300 degrees. 5. Cook for about 45 minutes, then start checking the roast's temperature with an instant-read thermometer.Remove the roast when the internal temperature, measured as deep into the roast as you can get, reads 165 degrees.6.. Heat the oven to 500 degrees for a raw roast, 375 for a pre-browned one. 4. Place the roasting pan in the oven; cook for 10 minutes, then lower the heat to 300 degrees. 5. Cook for about 45 minutes, then start checking the roast's temperature with an instant-read thermometer.