Diseases that mimic ALS. I am 35 yr Female, since December of 2010 I have had twitching in my legs,arms, feet and hands. Recently I have lost muscle in my hand (pinky joint with mild cramping) and forearm, right buttocks (large indent) and both thighs.
Jump to: navigation, search ... Deletion. Deletion is a type of mutation involving the loss of genetic material. It can be small, involving a single missing DNA base pair, or large, involving a piece of a chromosome.Narration Transcription ... s are the result of a loss of a section of the genetic material (chromosome) of the cell. If the deleted segment is small or it does not contain critical genes, the effect on the cell may be small. ~. (1) A deficiency in a chromosome resulting from the loss of a fragment through breakage.
Stop codon. In the genetic code, a stop codon (or termination codon) is a nucleotide triplet within messenger RNA that signals a termination of translation. Proteins are based on polypeptides, which are unique sequences of amino acids. Most codons in messenger RNA (from DNA) correspond to the addition of an amino acid to a growing polypeptide chain, which may ultimately become a protein. Stop codons signal the termination of this process by binding release factors, which cause the ribosomal subunits to disassociate, releasing the amino acid chain. While start codons need nearby sequences or initiation factors to start translation, a stop codon alone is sufficient to initiate termination.