Qualitative and quantitative factor deficiencies can affect the function of the coagulation pathways. Factor V and factor II (prothrombin) mutations are examples of qualitative deficiencies and are the most common inherited predisposing factors for blood clots.
Definition. A comma splice is a run on sentence, where two or more independent clauses are 'spliced' or split by a comma. A comma splice is considered a significant English error.
To correct comma splices and fused sentences: 1) Place a period after the first main (independent) clause and write the second main clause as a sentence; 2) use a semi-colon to separate main clauses; or 3) insert a coordinating conjunction (and, but, or, for, nor, so, yet) after the comma; or 4) make one clause subordinate to the other.