Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
Pakistan's 2nd most populous city, Lahore, is only about half the size, with just 6.3 million people, but is still the world's 15th most populous city. Pakistan has six additional cities that have passed the one million population mark.
During 2018 Pakistan population is projected to increased by 4,185,628 people and reach 203,216,893 in the beginning of 2019. The natural increase is expected to be positive, as the number of births will exceed the number of deaths by 4,426,455.