A detailed description of a wound suture and the suture materials used in it is by the Indian sage and physician Sushruta, written in 500 BC. The Greek father of medicine, Hippocrates, described suture techniques, as did the later Roman Aulus Cornelius Celsus.
The skeletal system of human helps maintain homeostasis by producing new red bloods cells where the old ones just die off. It also helps maintain the level of calcium in the blood stream.
As a whole, the integumentary system plays a big part in maintaining homeostasis. The integumentary system is the outermost organ system of the body and many of its functions are related to this location. The skin protects the body against pathogens and chemicals, minimizes loss or entry of water, and blocks the harmful effects of sunlight.