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metabolism. 1. biotransformation. 2. the sum of the physical and chemical processes by which living organized substance is built up and maintained (anabolism), and by which large molecules are broken down into smaller molecules to make energy available to the organism (catabolism).
metabolism meÂ·tabÂ·oÂ·lism (mÄ­-tÄb'É-lÄ­z'Ém) n. The complex of physical and chemical processes occurring within a living cell or organism that are necessary for the maintenance of life. In metabolism some substances are broken down to yield energy for vital processes while other substances, necessary for life, are synthesized.