Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
The enormous population of 23.5 million (23,500,000) is also due to the fact that Karachi is the main business center of, almost, all the corporations in Pakistan. Having population density of 6,663/km2, it is also a main hub of higher education in Muslim world. See Also; 10 Most Dangerous Cities in The World.
Following the Partition of British India, Lahore became the capital of Pakistan's Punjab province. Lahore is one of Pakistan's most liberal and cosmopolitan cities with a Muslim majority and a large Christian population. Additionally, Lahore is one of Sikhism's holiest cities and a major Sikh pilgrimage site. The city exerts a strong cultural influence over Pakistan.