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Integrin beta-1 also known as CD29 is a protein that in humans is encoded by the ITGB1 gene. CD29 is an integrin unit associated with very late antigen receptors.It is known to conjoin with alpha-3 subunit to create Î±3Î²1 complex that reacts to such molecules as netrin-1 and reelin.tructure [edit]. Integrin beta-1 can exist as different isoforms via alternative splicing. Six alternatively spliced variants have been found for this gene which encode five proteins with alternate C-termini.