The toxic effect is related linearly through a relatively large range of body weights, to the body weight of the victim, and, The mechanism of toxicity is the same for âsimilar animalsâ, i. e. one may conduct toxicity tests on say rats or mice and apply the LD50 data to human, since both are mammals.
For moderate menstrual cramps, the nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen [Advil, Motrin, Nuprin, etc.] or naproxen [Aleve, Anaprox, Naprosyn, Naprelan]) are often helpful.
Best Answer: Designed for menstrual cramps, it is ibuprofen. It works by interrupting arachadonic acid metabolism, thus interrupting leukotrienes. Blocking leukotrienes is what slows down the cramps. Basically, the uterus is a ball of wrapped smooth muscle. During your period it wants to get rid of the menstrual blood. To help this, the body makes extra leukotrienes which in this case has the effect of causing smooth muscle to spasm, this ejecting the blood.