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Penile Discharge Fact Sheet Save this for later. Table of Contents. Penile discharge is the abnormal loss of fluid that is not urine or semen from the urethra at the tip of the penis. It is commonly the sign of a sexually transmitted disease (STD), and requires prompt and accurate diagnosis and treatment.
Other common causes of UTIs include the following: 1  Urethritis: Burning urination is often the result of urethritis, the infection of the urethra. 2  In men, urethritis can also cause penile discharge. 3  Pyelonephritis: Pyelonephritis occurs when a bladder infection spreads to the kidneys.