The toxic effect is related linearly through a relatively large range of body weights, to the body weight of the victim, and, The mechanism of toxicity is the same for âsimilar animalsâ, i. e. one may conduct toxicity tests on say rats or mice and apply the LD50 data to human, since both are mammals.
For moderate menstrual cramps, the nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen [Advil, Motrin, Nuprin, etc.] or naproxen [Aleve, Anaprox, Naprosyn, Naprelan]) are often helpful.
â¢ You may have cramps and heavy periods. Ibuprofen can help. You can take up to 4 pills. (800 mg) of Ibuprofen every 8 hours with food. To prevent cramps, take Ibuprofen when your. period starts and keep taking it every 8 hours for the first 2-3 days of your period.