Neither of these things are guaranteed to happen if you get the flu vaccine when you are sick, but they are possibilities. If you have just a mild illness, there is no reason to wait to get vaccinated.
Early in the day, let roast stand at room temperature at least 1 hour before cooking. Preheat oven to 375 degrees. Rub meat ... the outside and rare in the middle. Meat will be very brown ... stand at room temperature for at least one hour.
1 Set the roast on a rack in a roasting pan (fat side up) and put into a 450 degree F preheated oven for 15 minutes (be sure oven is preheated). 2  Turn oven down to 350 degrees F and continue roasting until your meat thermometer reads.