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metabolism. 1. biotransformation. 2. the sum of the physical and chemical processes by which living organized substance is built up and maintained (anabolism), and by which large molecules are broken down into smaller molecules to make energy available to the organism (catabolism).
Metabolism, Human. Metabolism means the sum of all chemical changes in a cell or the body of an organism. It has two subdivisions: catabolism and anabolism. Catabolism (from the Greek cata, meaning down) consists of all those reactions in which large molecules are broken down into smaller ones, with a release of energy from their chemical bonds.