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Crohn's disease is caused by a combination of environmental, immune and bacterial factors in genetically susceptible individuals. It results in a chronic inflammatory disorder, in which the body's immune system attacks the gastrointestinal tract possibly directed at microbial antigens.
Crohn's disease is a lifelong inflammatory bowel disease (IBD) . Parts of the digestive system get swollen and have deep sores called ulcers. Crohn's disease usually is found in the last part of the small intestine and the first part of the large intestine.But it can develop anywhere in the digestive tract, from the mouth to the anus. Doctors don't know what causes Crohn's disease.arts of the digestive system get swollen and have deep sores called ulcers. Crohn's disease usually is found in the last part of the small intestine and the first part of the large intestine. But it can develop anywhere in the digestive tract, from the mouth to the anus. Doctors don't know what causes Crohn's disease.