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Symptoms of a sinus infection during pregnancy. Sinusitis can develop at any point during the first, second, or third trimester of pregnancy. This is an infection and inflammation in the lining of your sinuses, which are air-filled pockets located around the face and nose. A sinus infection can cause different symptoms, including: mucus drainage.
While some medications are not safe during pregnancy, there are nasal sprays that have been FDA approved for sinus congestion. To help pregnant women distinguish between safe nasal sprays that exist and those that are unsafe, there are FDA-assigned pregnancy categories used in the FDAâs Drug Formulary.