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Note that the possible height of cloud varies with location and airmass, so the highest cloud can occur in the tropics, the lower heights (with cirrus possible at 10,000 ft or 3500 m) in polar regions.
The biggest known by mass is R136a1 : see List of most massive stars. The largest known by volume is UY Scuti : see List of largest stars. R136a1 is in the nearby Large Magellanic Cloud , where it is also relatively easy to see things and be certain of their distance. UY Scuti is a mere 9,500 light-years away: our own galaxy is at least 100,000 light-years across.