Aripiprazole is effective for the treatment of acute manic episodes of bipolar disorder in adults, children, and adolescents. Used as maintenance therapy, it is useful for the prevention of manic episodes, but is not useful for bipolar depression.
The enormous population of 23.5 million (23,500,000) is also due to the fact that Karachi is the main business center of, almost, all the corporations in Pakistan. Having population density of 6,663/km2, it is also a main hub of higher education in Muslim world. See Also; 10 Most Dangerous Cities in The World.
The climate of Pakistan. Pakistan is a country located in South-Asia and has one of the largest populations in the world. Most people live in urban areas. Karachi is the largest city with a population of more than 12 million. The landscape of Pakistan varies from low areas in the eastern and southern parts of the country to high plains and high mountain areas in the western and northern parts of the country.