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Possible causes of bladder outlet obstruction might include: 1  Enlarged prostate, also known as benign prostatic hyperplasia (BPH) â this is the most common cause of bladder outlet obstruction in men. 2  Scarring of the urinary channel (urethra) or bladder neck, as a result of injury or surgery.
Following are some important causes: Urinary tract causes: 1  A large sized stone in bladder can block the urine outflow and cause accumulation of urine in bladder.  Similarly prostate enlargement (Benign prostate hypertrophy, BPH) may obstruct the urethral passage and cause retention of urine with bladder distension.