Neither of these things are guaranteed to happen if you get the flu vaccine when you are sick, but they are possibilities. If you have just a mild illness, there is no reason to wait to get vaccinated.
Early in the day, let roast stand at room temperature at least 1 hour before cooking. Preheat oven to 375 degrees. Rub meat ... the outside and rare in the middle. Meat will be very brown ... stand at room temperature for at least one hour.
How long and at what temperature should I cook a beef roast in the oven? Roasting is a great cooking method for a large, tender cut of beef  such as a rib or sirloin roast.Sirloin-tip, rump, rolled-rump, eye-of-round or top-round roasts will also benefit from this cooking method if they are graded prime or choice.ow long and at what temperature should I cook a beef roast in the oven? Roasting is a great cooking method for a large, tender cut of beef  such as a rib or sirloin roast.