Lyme disease is transmitted to humans by the bite of infected ticks of the Ixodes genus. Usually, the tick must be attached for 36 to 48 hours before the bacteria can spread. In North America, Borrelia burgdorferi sensu stricto and Borrelia mayonii are the cause.
A genetic predisposition (sometimes also called genetic susceptibility) is an increased likelihood of developing a particular disease based on a personâs genetic makeup. A genetic predisposition results from specific genetic variations that are often inherited from a parent.he World Health Organization offers information about genetic predisposition to several common diseases, including cancer, diabetes, cardiovascular disease, and asthma. Genetic Alliance UK offers a fact sheet on genetic predisposition to common genetic diseases.
Changes in many genes, each with a small effect, may underlie susceptibility to many common diseases, including cancer, obesity, diabetes, heart disease, and mental illness. In people with a genetic predisposition, the risk of disease can depend on multiple factors in addition to an identified genetic change.These include other genetic factors (sometimes called modifiers) as well as lifestyle and environmental factors.enetic variations can have large or small effects on the likelihood of developing a particular disease. For example, certain mutations in the BRCA1 or BRCA2 genes greatly increase a personâs risk of developing breast cancer and ovarian cancer.