Mechanism of Action. Levocetirizine, the active enantiomer of cetirizine, is an anti histamine; its principal effects are mediated via selective inhibition of H1 receptors. The antihistaminic activity of levocetirizine has been documented in a variety of animal and human models. In vitro binding studies revealed that levocetirizine has an affinity for the human H1-receptor 2-fold higher than that of cetirizine (Ki = 3 nmol/L vs. 6 nmol/L, respectively).
A glacier calf, or chunk of ice, measuring nearly five square miles broke away from Greenland's Jakobshavn glacier sometime in August, making it the largest piece to ever break away from one of the world's fastest melting glaciers. glacier, calf, iceberg, jakobshavn, greenland.
Satellites have now spotted it off the coast of Labrador, Canada, as seen in a new image. The ice island was formed when a 97-square-mile chunk of ice broke off Greenland's Petermann Glacier on Aug. 5, 2010. It was the largest iceberg to form in the Arctic in 50 years. Petermann Glacier is one of the two largest remaining glaciers in Greenland that terminate in floating shelves.