Menorrhagia is defined as menstruation at regular cycle intervals but with excessive flow and duration and is one of the most common gynecologic complaints in contemporary gynecology. See the image below. Acute menorrhagia requires prompt medical intervention. This is bleeding that will compromise an untreated patient.
Haemophilia A (Factor VIII Deficiency) is a bleeding disorder caused by deficiency of clotting factor VIII. Medical advise about Haemophilia A (Factor VIII Deficiency) Patient Access
Factor VIII participates in blood coagulation; it is a cofactor for factor IXa which, in the presence of Ca 2+ and phospholipids forms a complex that converts factor X to the activated form Xa. The factor VIII gene produces two alternatively spliced transcripts.