Clinical observations include estimation of haemoglobin-oxygen saturation (SpO 2, pulse oximetry), oxygen delivery, respiratory rate, respiratory distress, heart/pulse rate, blood pressure (systolic, diastolic and mean), temperature, level of consciousness OR level of sedation, and a pain score.linical observations include estimation of haemoglobin-oxygen saturation (SpO 2, pulse oximetry), oxygen delivery, respiratory rate, respiratory distress, heart/pulse rate, blood pressure (systolic, diastolic and mean), temperature, level of consciousness OR level of sedation, and a pain score.
In turn this triggers the sarcoplasmic reticulum to release calcium ions into the muscle interior where they bind to troponin, thus causing tropomyosin to shift from the face of the actin filament to which myosin heads need to bind to produce contraction.
Cardiac-muscle contraction is actin-regulated, meaning that the calcium ions come both from the sarcoplasmic reticulum (as in skeletal muscle) and from outside the cell (as in smooth muscle). Otherwise, the chain of events that occurs in cardiac-muscle contraction is similar to that of skeletal muscle.