Mechanism of Action. Levocetirizine, the active enantiomer of cetirizine, is an anti histamine; its principal effects are mediated via selective inhibition of H1 receptors. The antihistaminic activity of levocetirizine has been documented in a variety of animal and human models. In vitro binding studies revealed that levocetirizine has an affinity for the human H1-receptor 2-fold higher than that of cetirizine (Ki = 3 nmol/L vs. 6 nmol/L, respectively).
Glacier Calf That Broke Off Greenland's Jakobshavn Could Be Largest Ever. The Jakobshavn glacier-Greenland's fastest-moving glacier located near Ilulissat-is seen in a NASA image taken by the Operational Land Imager (OLI) on the Landsat 8 satellite August 16, 2015.
Karim Sahai Photographer. At 225Kg, Guhonda is the largest silverback mountain gorilla in the world. He is the alpha male of the Sabinyo group and is often seen in the company of one of the groupâs several adult females. Rwandaâs Volcanos National Park (Parc National Des Volcans) is home to some of the critically endangered mountain gorillas.