Menorrhagia is defined as menstruation at regular cycle intervals but with excessive flow and duration and is one of the most common gynecologic complaints in contemporary gynecology. See the image below. Acute menorrhagia requires prompt medical intervention. This is bleeding that will compromise an untreated patient.
Haemophilia A (Factor VIII Deficiency) is a bleeding disorder caused by deficiency of clotting factor VIII. Medical advise about Haemophilia A (Factor VIII Deficiency) Patient Access
Leukocyte adhesion deficiency type II is extremely rare; only a handful cases have been reported and most of them are of Middle Eastern decent. It is a defect in the expression of ligands for selectins due to lack of enzymes required for expression of selectin ligands.hus, patients with this type of leukocyte adhesion deficiency manifest both severe bacterial infections and bleeding disorder. This leukocyte adhesion deficiency variant is associated with defective expression of the Rap-1 activator CalDAG-GEFI. Rap-1 is an essential protein involved in signaling mediated by integrins.