Doctors don't know what causes Paget's disease of the breast. The most widely accepted theory is that the disease results from an underlying ductal breast cancer. The cancer cells from the original tumor then travel through milk ducts to the nipple and its surrounding skin.
Glucose in the bloodstream provides the primary fuel for all body tissues. Blood glucose levels are highest during the digestive period after a meal. Your blood sugar is lowest when the stomach and intestines are empty. Under normal circumstances, the body tightly controls the amount of insulin in your blood. An organ called the pancreas, which is tucked behind the stomach releases the hormones insulin and glucagon to regulate blood sugar levels.
Homeostasis of Blood Glucose Levels. Glucose is the main source of fuel for the cells in our bodies, but it's too big to simply diffuse into the cells by itself. Instead, it needs to be transported into the cells. Insulin is a hormone produced by the pancreas that facilitates glucose transport into cells. By facilitating glucose transport into cells from the bloodstream, insulin lowers blood glucose levels. It also inhibits glucose production from amino acids, fatty acids and glycogen which, you may remember, is a carbohydrate composed of many glucose subunits.