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In primary hyperparathyroidism, the elevated levels of PTH cause elevated levels of blood calcium (hypercalcemia). Increased calcium and phosphorus excretion in the urine may cause kidney stones. The most common cause of primary hyperparathyroidism is a benign tumor called an adenoma on one of the parathyroid glands that secretes too much PTH. In other cases, the excess PTH is produced by two or more enlarged parathyroid glands, a condition called hyperplasia.
Hyperthyroidism is caused by an overactive thyroid, which means the thyroid produces too much hormone. This can cause rapid heart rate, high blood pressure, and unexpected or sudden weight loss. Hypothyroidism is caused by an underactive thyroid, which means the thyroid doesnât produce enough hormones.