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A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. The plural of locus is loci. locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. The plural of locus is loci.
Genetic locus. The location of a gene (or of a significant sequence) on a chromosome or on a linkage map. For example, the locus of the gene OCA1 (or Oculocutaneous Albinism Type 1, the gene associated with albinism) is on 11q1.4-a2.1, which means it is on the long arm of chromosome 11, between sub-band 4 of band 1 to sub-band 1 of band 2. Word origin: locus Â» Latin stlocus, a place.