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Black widow spider bites can cause severe abdominal pain or cramping. Brown recluse spider bites can cause a sting or sharp pain, like a bee sting. With severe bites, surrounding skin may die within a few hours. Both types of spiders generally live in undisturbed areas, such as attics or sheds.
Yet, occasionally, a spider's bites will cause real harm. Spider bites may cause injury by three mechanisms. First, especially with larger spiders, the bite itself may be painful and cause injury. However, far more concerning is the spider's venom, which can include necrotic agents or neurotoxins.