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A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. The plural of locus is loci. locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. The plural of locus is loci.
Noun. 1. gene - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; genes were formerly called factors. cistron, factor.