Mechanism of Action. Levocetirizine, the active enantiomer of cetirizine, is an anti histamine; its principal effects are mediated via selective inhibition of H1 receptors. The antihistaminic activity of levocetirizine has been documented in a variety of animal and human models. In vitro binding studies revealed that levocetirizine has an affinity for the human H1-receptor 2-fold higher than that of cetirizine (Ki = 3 nmol/L vs. 6 nmol/L, respectively).
The ice island, which is about half the height of the Empire State Building, is the biggest piece of ice to break away from the Arctic icecap since 1962 and amounts to a quarter of the Petermann 70-kilometer floating ice shelf, according to research leader Andreas Muenchow.
Interdisciplinary Science at the Bering Glacier. The Bering Glacier is the largest and longest glacier in continental North America and is the largest temperate surging glacier on earth. The Bering Glacier has surged at least six times during the twentieth century, and the last surge occurred in 1993-1995. The Glacier is currently retreating, and scientists from MTRI have been conducting research at the Glacier during a period spanning almost a decade.