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Four tests â thyroid-stimulating hormone (TSH), Free T3, Free T4 and thyroid antibodies â are required to accurately assess the function of the thyroid gland, our master gland of metabolism. An optimal TSH level should be less than 2.0, not the currently accepted 4.7 reported by most labs.
Small changes that can influence the effect of thyroid medication on your body include: 1  Changing the time of day you take your dose. 2  Taking the medication on an empty stomach, then switching to taking it with food. 3  Switching brands of levothyroxine.