Lyme disease is transmitted to humans by the bite of infected ticks of the Ixodes genus. Usually, the tick must be attached for 36 to 48 hours before the bacteria can spread. In North America, Borrelia burgdorferi sensu stricto and Borrelia mayonii are the cause.
A genetic predisposition (sometimes also called genetic susceptibility) is an increased likelihood of developing a particular disease based on a personâs genetic makeup. A genetic predisposition results from specific genetic variations that are often inherited from a parent.he World Health Organization offers information about genetic predisposition to several common diseases, including cancer, diabetes, cardiovascular disease, and asthma. Genetic Alliance UK offers a fact sheet on genetic predisposition to common genetic diseases.
Markers can be an expressed region of DNA (gene encoding a protein) or a segment of DNA with no known coding function but whose pattern of inheritance can be determined. A marker can be localised to a specific region of the genome (e.g., all markers on the human transcript map are STSs). Markers have also been defined as a genetic trait, of which one allelic form is selected or screened for after recombination. Suicidology A potential physiologic indicator or predictor of an increased risk of suicide, the most promising of which is a decrease in serotonin in the brain. marker