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Four tests â thyroid-stimulating hormone (TSH), Free T3, Free T4 and thyroid antibodies â are required to accurately assess the function of the thyroid gland, our master gland of metabolism. An optimal TSH level should be less than 2.0, not the currently accepted 4.7 reported by most labs.
Synthroid and Weight Loss. The thyroid gland secretes a hormone that regulates metabolism. Because Synthroid works to replace this hormone, long-term use can lead to some of the characteristics of an overactive metabolism. As a result, over time people taking Synthroid can lose weight and have their appetite increase.he thyroid gland secretes a hormone that regulates metabolism. Because Synthroid works to replace this hormone, long-term use can lead to some of the characteristics of an overactive metabolism.