Debris from Total Hip Replacement or Hip Resurfacing Procedures. After total hip replacement or hip resurfacing, particle debris from the cup, ball or ball covering can lead to complications and implant failure. As the implant recipient moves, the surfaces of the components rub against each other. The friction and abrasive wear between the components produces debris.
Reverse transcriptase is the viral enzyme responsible for making a DNA copy of the RNA genome from a retrovirus. As such, it is technically known as an RNA-dependent DNA polymerase. This is opposite to the usual flow of genetic information from DNA to RNA to protein.
The basic mechanism by which enzymes catalyze chemical reactions begins with the binding of the substrate (or substrates) to the active site on the enzyme. The active site is the specific region of the enzyme which combines with the substrate. The binding of the substrate to the enzyme causes changes in the distribution of electrons in the chemical bonds of the substrate and ultimately causes the reactions that lead to the formation of products.