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Bacitracin is a powerful antibiotic, but it is rarely used internally, because it is considered toxic and difficult to control. However, the use of bacitracin ointment may be effective in reducing numerous infections that affect the skin of canines.
Bacitracin is primarily used as a topical preparation (as it can cause kidney damage when used internally). While the use of any antibiotic can contribute to antibiotic resistance, localized topical applications are less frequently implicated than their systemic counterparts.