Doctors don't know what causes Paget's disease of the breast. The most widely accepted theory is that the disease results from an underlying ductal breast cancer. The cancer cells from the original tumor then travel through milk ducts to the nipple and its surrounding skin.
Glucose in the bloodstream provides the primary fuel for all body tissues. Blood glucose levels are highest during the digestive period after a meal. Your blood sugar is lowest when the stomach and intestines are empty. Under normal circumstances, the body tightly controls the amount of insulin in your blood. An organ called the pancreas, which is tucked behind the stomach releases the hormones insulin and glucagon to regulate blood sugar levels.
Cells in the pancreas make enzymes which help with digestion-but other pancreatic cells (known as the Islets of Langerhans) make the hormones which control your blood glucose levels too. When your blood sugar levels fall below the ideal level your pancreas releases a different hormone called glucagon.