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1 Ethmoid Sinus Cavities â are located in-between the eyes. 2  An infection in these sinus cavities can cause pain in-between the eyes. 3  This pain can extend to the forehead and cause headaches. 4  Frontal Sinus Cavities â are found above the eye and eye bone.
There are multiple sinuses in your skull, above the nose and eyes, below the eyes, and between the eyes. They all drain into the nose. Any one or more of these sinuses can be affected with either sinusitis or an infection leading to pain and tenderness to touch. This could also be a skin infection.