Mechanism of Action. Levocetirizine, the active enantiomer of cetirizine, is an anti histamine; its principal effects are mediated via selective inhibition of H1 receptors. The antihistaminic activity of levocetirizine has been documented in a variety of animal and human models. In vitro binding studies revealed that levocetirizine has an affinity for the human H1-receptor 2-fold higher than that of cetirizine (Ki = 3 nmol/L vs. 6 nmol/L, respectively).
Glacier Calf That Broke Off Greenland's Jakobshavn Could Be Largest Ever. The Jakobshavn glacier-Greenland's fastest-moving glacier located near Ilulissat-is seen in a NASA image taken by the Operational Land Imager (OLI) on the Landsat 8 satellite August 16, 2015.
Antarctica is one of the Earthâs icy poles, and this is one of its main glaciers. In fact, it is currently the worldâs largest glacier according to Guinness World Records, as it measures 400km (250 miles) long, 100km (60 miles) wide and roughly 2.5km (1 mile) deep.