Severe defects of the pyruvate dehydrogenase (PDH) complex and the benign chemical anomaly called pentosuria have been reported in very few (2-6) patients. Patients with inherited disorders of carbohydrate metabolism tend to be seen at tertiary centers, where specialist teams are available.
The phrase âletâs play it by earâ is used when someone wants to basically say âletâs not make any concrete plans â instead, letâs just see how things turn out and then we will decide what to do.â The phrase is used when talking about future plans, so itâs always referencing the future.
play it by ear. 1  to decide how to deal with a situation as it develops rather than planning how you are going to react I'm not sure how long I'll stay at the party. 2  To act according to the circumstances; improvise: I don't have a set schedule, so we'll have to play it by ear.