Whereas the content standards will provide the topic of the lesson and what exactly the students should be doing with that topic (e.g., solving problems, creating models, ranking ideas), the English language proficiency or development standards help to identify language skills and functions that students should be working on to achieve academic language fluency.
Tay-Sachs disease is a gangliosidosis characterised by: An exaggerated startle response. Delay in psychomotor development. Hypotonia (followed by spasticity) Visual loss. A macular cherry-red spot. Pathogenesis. Tay-Sachs disease (and its variants) are caused by absence or defects of the alpha subunit of hexosaminidase A.
Tay-Sachs disease and resistance to tuberculosis. Tay-Sachs is a rare genetic disease that results in an abnormal accumulation of neuronal lipids caused by a defective lysosomal enzyme, Î±-hexosaminidase. Alleles for this disease are more prevalent in certain populations, the most well-known being the Ashkenazi Jews.t is of note that a particular genetic disorder leads to infectious disease hypersusceptibility, and this relationship has provided the basis for a preventative. Specifically, the relationship between hemosiderosis and typhoid fever has led to the development of a vaccine that intervenes in this relationship.