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Fifth disease is transmitted through respiratory droplets and contact with infected blood products. The incubation period (the time between the initial infection and the onset of symptoms) is usually between 4 and 21 days. People with fifth disease are most contagious before the onset of symptoms.ifth disease is transmitted through respiratory droplets and contact with infected blood products. The incubation period (the time between the initial infection and the onset of symptoms) is usually between 4 and 21 days. People with fifth disease are most contagious before the onset of symptoms.
Outbreaks occur most often during the winter and spring months. Fifth disease is quite contagious, with cases following each other by 4 to 14 days. Keeping the hands clean with instant hand sanitizers can help to interrupt the spread of this infection, which is spread by respiratory droplets.