The fourth great shinobi war was Started in: 1  In anime, Naruto shippuden episode 261. 2  In manga, it was chapter 516.
Neural sensitization is the process by which the response of a neuron to a given stimulus is increased. This increase lasts a long time-weeks or months at least.
Stress sensitization is uncharitably subversive. While the chemical signaling systems of body and brain are running amok in a person sensitized to stress, that person's perception of stress remains unchanged. It's as if the brain, aware that the burner on the stove is cool, still signals the body to jerk its hand away.