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Coronary Heart Disease. Coronary heart disease (CHD), also called coronary artery disease, occurs when plaque builds up in the coronary arteries. These arteries supply oxygen-rich blood to your heart. Plaque narrows the coronary arteries and reduces blood flow to your heart muscle. Plaque buildup also makes it more likely that blood clots will form in your arteries. Blood clots can partially or completely block blood flow.
The arteries are major blood vessels connected to your heart. 1  The pulmonary artery carries blood from the right side of the heart to the lungs to pick up a fresh supply of oxygen. 2  The aorta is the main artery that carries oxygen-rich blood from the left side of the heart to the body. The coronary arteries are the other important arteries attached to the heart. They carry oxygen-rich blood from the aorta to the heart muscle, which must have its own blood supply to function.