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Gangrene is a condition that occurs when body tissue dies. It is caused by a loss of blood supply due to an underlying illness, injury, and/or infection. Fingers, toes, and limbs are most often affected, but gangrene can also occur inside the body, damaging organs and muscles.
Freebase(0.00 / 0 votes)Rate this definition: Gangrene is a serious and potentially life-threatening condition that arises when a considerable mass of body tissue dies. This may occur after an injury or infection, or in people suffering from any chronic health problem affecting blood circulation.