NOTE: Documentation requirements are complex and may be subject to change at any time. Therefore, all cruise passengers should visit www.travel.state.gov (U.S. Department of State) or other authoritative source for the latest passport and visa requirements as well as any overseas travel advisories.
Ingenol mebutate (ingenol-3-angelate, PEP005, LEO Pharma trade name Picato) is a substance found in the sap of the plant Euphorbia peplus and an inducer of cell death.dverse effects [edit]. Irritations of the application site are very common. This includes redness, scaling, crusting, pain, pruritus, and sometimes infection. Other side effects include eye irritation such as periorbital edema (3% of patients in studies), headache (2%) and nasopharyngitis (running nose, 2%).
Gelato, Italy's low fat version of ice cream, has become popular with American ice cream lovers because it contains fewer calories than traditional ice cream. Gelato, made with skimmed milk and slightly less sugar than ice cream, contains a minimum of 4 percent milk fat and is flavored with fruits, nuts and chocolate. Gelato is also served at a warmer temperature than ice cream, making the flavors easier to taste.