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Best Answer: The song is referring to men as dirty dogs let out on the prowl. Something like that. WOOF... Who Let the Dogs Out is a song by Baha Men. There could be different interpretations of the meaning, but given the song's lyrics, I think that the phrase refers to men chasing after women. Figuratively the men would become like dogs (eager, rowdy, loyal, etc.) when they saw women.
The song is actually called O.P.P. sung by Naughty by Nature. Short answer: Other Peoples Pussy, Penis, or Property. It is about cheating. If you're Down with O.P.P., it means you're willing to do someone else's boyfriend or girlfriend. Not exactly family values, but it's presented in a fun and clever way that doesn't say exactly what the last letter means, but gives very strong hints.