constituting or forming a large number; numerous: many people. noting each one of a large number (usually followed by a or an): For many a day it rained. a large or considerable number of persons or things: A good many of the beggars were blind. the many, the greater part of humankind. many persons or things: Many of the beggars were blind.
Hives and angioedema can be caused by: 1  Foods. Many foods can trigger reactions in people with sensitivities. 2  Medications. Almost any medication may cause hives or angioedema. 3  Common allergens. Other substances that can cause hives and angioedema include pollen, animal dander, latex and insect stings.  Environmental factors.
Hives frequently occur following an infection or as a result of an allergic reaction such as to medication, insect bites, or food. Psychological stress, cold temperature, or vibration may also be a trigger. In half of cases the cause remains unknown. Risk factors include having conditions such as hay fever or asthma.