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1,4-Dihydropyridine (DHP), an important class of calcium antagonist, inhibits the influx of extracellular Ca+2 through L-type voltage-dependent calcium channels. Three-dimensional (3D) structure of calcium channel as a receptor for 1,4-dihydropyridine is a step in understanding its mode of action. Protein structure prediction and modeling tools are becoming integral parts of the standard toolkit in biological and biomedical research.
Calcium channel blockers: These are prescription medications that help to dilate or enlarge the blood vessels, thereby. 1  increasing circulation to the extremities. These medications are helpful in reducing the severity and frequency of attacks. Some medications used are: nifedipine and diltiazem.