Somewhat more formally, for a set Ï of properties and relations, a Ï-representation of some structure X is a structure Y that is the image of X under a s homomorphism that preserves Ï. The label representation is sometimes also applied to the homomorphism itself.
Melanoma. This cancer begins in the melanocytes, the cells that provide the skinâs color. Melanoma is one of the deadliest forms of skin cancer because it can spread rapidly inside the body. Approximately one American dies from melanoma every hour.
Screening for targets of the melanocyte lineage is highly relevant to melanoma because melanocytes are the melanoma cell of origin, and genes that specify the melanocyte stem cells and the lineage during embryogenesis are the same genes that play fundamental roles in cancer.