Mechanism of Action. Levocetirizine, the active enantiomer of cetirizine, is an anti histamine; its principal effects are mediated via selective inhibition of H1 receptors. The antihistaminic activity of levocetirizine has been documented in a variety of animal and human models. In vitro binding studies revealed that levocetirizine has an affinity for the human H1-receptor 2-fold higher than that of cetirizine (Ki = 3 nmol/L vs. 6 nmol/L, respectively).
The ice island, which is about half the height of the Empire State Building, is the biggest piece of ice to break away from the Arctic icecap since 1962 and amounts to a quarter of the Petermann 70-kilometer floating ice shelf, according to research leader Andreas Muenchow.
Kabir, Page 340, Adi Granth. Descending from 19,000 feet to 12,000 feet, over a length of 70 km, Siachen glacier (âplace of wild rosesâ) is the worlds highest battleground since the year 1984. India controls its entire glacial length, adjoining peaks and the three passes, which are the gateway between Karakoram and Ladakh.