constituting or forming a large number; numerous: many people. noting each one of a large number (usually followed by a or an): For many a day it rained. a large or considerable number of persons or things: A good many of the beggars were blind. the many, the greater part of humankind. many persons or things: Many of the beggars were blind.
Hives and angioedema can be caused by: 1  Foods. Many foods can trigger reactions in people with sensitivities. 2  Medications. Almost any medication may cause hives or angioedema. 3  Common allergens. Other substances that can cause hives and angioedema include pollen, animal dander, latex and insect stings.  Environmental factors.
Angioedema is a form of hives where the swelling occurs beneath the skin rather than on the surface. Angioedema, found in about 30 percent of adults with chronic urticaria, is characterized by deep swelling around the eyes and lips.hronic urticaria is a chronic case of hives that last six weeks or more, and is often caused by a trigger that is difficult or impossible to identify. People with no known cause for their chronic hives may be diagnosed with Chronic Idiopathic Urticaria (CIU).