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Fifth disease is transmitted through respiratory droplets and contact with infected blood products. The incubation period (the time between the initial infection and the onset of symptoms) is usually between 4 and 21 days. People with fifth disease are most contagious before the onset of symptoms.ifth disease is transmitted through respiratory droplets and contact with infected blood products. The incubation period (the time between the initial infection and the onset of symptoms) is usually between 4 and 21 days. People with fifth disease are most contagious before the onset of symptoms.
Slapped cheek disease (also known as fifth disease or parvovirus B19). Incubation period: 1-20 days. Infectious period: A few days before the rash appears (children are no longer contagious when the rash appears).Symptoms: 1  It begins with a fever and nasal discharge.2  A bright red rash, like the mark left by a slap, appears on the cheeks.ncubation period: 1-20 days. Infectious period: A few days before the rash appears (children are no longer contagious when the rash appears). Symptoms: 1  It begins with a fever and nasal discharge. 2  A bright red rash, like the mark left by a slap, appears on the cheeks.