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The most common side effects of niacin are: stomach upset, flushing, headache, reduced blood pressure upon standing (orthostatic hypotension), vomiting, diarrhea, itching and ; tingling sensations of the extremities. Flushing may be reduced by taking 325 mg of aspirin 30 minutes before the niacin and by increasing the dose of niacin slowly.
Taking niacin supplements without medical supervision can cause side effects. Among the common effects is niacin flush -- redness in your skin, accompanied by a burning or tingling sensation -- caused by dilated blood vessels at your skin's surface.Taking too much niacin can also cause liver damage or blurred vision.itamin B-3 also helps regulate your blood pressure and plays a role in your cardiovascular health. Niacin acts as a blood vessel dilator -- it helps your blood vessels relax and widen to increase blood flow.