Mechanism of Action. Levocetirizine, the active enantiomer of cetirizine, is an anti histamine; its principal effects are mediated via selective inhibition of H1 receptors. The antihistaminic activity of levocetirizine has been documented in a variety of animal and human models. In vitro binding studies revealed that levocetirizine has an affinity for the human H1-receptor 2-fold higher than that of cetirizine (Ki = 3 nmol/L vs. 6 nmol/L, respectively).
Glacier Calf That Broke Off Greenland's Jakobshavn Could Be Largest Ever. The Jakobshavn glacier-Greenland's fastest-moving glacier located near Ilulissat-is seen in a NASA image taken by the Operational Land Imager (OLI) on the Landsat 8 satellite August 16, 2015.
Malaspina Glacier in Alaska is one of the most famous examples of this type of glacier, and is the largest piedmont glacier in the world. Spilling out of the Seward Icefield, Malaspina Glacier covers about 3,900 square kilometers (1,500 square miles) as it spreads across the coastal plain.ce Aprons. These small, steep glaciers cling to high mountainsides. Like cirque glaciers, they are often wider than they are long. Ice aprons are common in the Alps and in New Zealand, where they often cause avalanches due to the steep inclines they occupy.