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Medications that can cause night sweats. Night sweats are a common side effect of many medications, such as: 1  Depression medications (antidepressants). 2  Drugs used to regulate your hormones (hormone therapy). 3  Drugs that lower the level of sugar in your blood (hypoglycemic agents).
Some of the known conditions that can cause night sweats are: 1  Menopause. The hot flashes that accompany menopause can occur at night and cause sweating. 2  Idiopathic hyperhidrosis. Idiopathic hyperhidrosis is a condition in which the body chronically produces too much sweat without any identifiable medical cause. 3  Infections.