1 Cancer. 2  All tobacco smoke contains chemicals that can cause cancer, and cigar smoke is no exception. 3  Regular cigar smoking increases the risk of several types of cancers, including cancers of the mouth, lip, tongue, throat, esophagus, larynx and lung. 4  Lung and heart disease.
Results Of the three nicotinic receptor agonists tested, [3H]cytisine displayed the highest affinity for the neu- ronal nicotinic receptor (Table 1). It had a significantly higher affinity of 0.145 + 0.011 nM (P < 0.05, Fig. 1A) as compared to KD values of 0.89 + 0.06 and 1.07 _+ 0.13 nM for [3H]nicotine (Fig.
In the human body, Cytisine plays the role of nicotine substitution substance, and reduces the period of interaction of the received nicotine with relevant nicotine receptors, i.e. the specific substance cytisine substitutes nicotine, acting on the same receptors, thus preventing the appearance of abstinence syndrome.