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Fifth disease is transmitted through respiratory droplets and contact with infected blood products. The incubation period (the time between the initial infection and the onset of symptoms) is usually between 4 and 21 days. People with fifth disease are most contagious before the onset of symptoms.ifth disease is transmitted through respiratory droplets and contact with infected blood products. The incubation period (the time between the initial infection and the onset of symptoms) is usually between 4 and 21 days. People with fifth disease are most contagious before the onset of symptoms.
Doctor's Response: The incubation period -- the time that elapses between contracting parvovirus B19 (the virus of fifth disease) and the start of the illness -- is 4 to 12 days. A person infected with parvovirus B19 is only contagious during the early part of the illness, before the rash appears. This contagious period for fifth disease is different than that for many other rash illnesses, such as measles, for which the child is contagious while he or she has the rash.