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Agonist. Definition. noun, plural: agonists. (pharmacology) A molecule that combines with a receptor on a cell to trigger physiological reaction. An example is an acetylcholine being the agonist that combines with the cholinergic receptor. (histology) A muscle that contracts while another muscle relaxes, e.g. when bending the elbow the biceps are the agonist.
FULL AGONISTS, PARTIAL AGONISTS, ANTAGONISTS. Three types of opioids are classified by the effect that they have on the mu receptors on cells. They are the full agonist, the partial agonist and the antagonist. As used here, an agonist is something that stimulates or produces an effect. Agonist is derived from the Late Latin agnista which means contender which is derived from the Greek agonists which also means contestant which came from agon which means contest. An agonist is a chemical contestant or contender.