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A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. The plural of locus is loci. locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. The plural of locus is loci.
Locus. Definition. noun, plural: loci. (general) A place, space or locality, especially a centre of an activity. (mathematics) The set of all points whose coordinates satisfy a given equation or condition. (genetics) The location of a gene (or of a significant sequence) on a chromosome, as in genetic locus.(medicine) The site on the body where a pathogen enters. Supplement.efinition. noun, plural: loci. (general) A place, space or locality, especially a centre of an activity. (mathematics) The set of all points whose coordinates satisfy a given equation or condition.