Mechanism of Action. Levocetirizine, the active enantiomer of cetirizine, is an anti histamine; its principal effects are mediated via selective inhibition of H1 receptors. The antihistaminic activity of levocetirizine has been documented in a variety of animal and human models. In vitro binding studies revealed that levocetirizine has an affinity for the human H1-receptor 2-fold higher than that of cetirizine (Ki = 3 nmol/L vs. 6 nmol/L, respectively).
A glacier calf, or chunk of ice, measuring nearly five square miles broke away from Greenland's Jakobshavn glacier sometime in August, making it the largest piece to ever break away from one of the world's fastest melting glaciers. glacier, calf, iceberg, jakobshavn, greenland.
The larger glaciers of Eastern Jostedalsbreen. Jostedalsbreen is Norway s and continental Europe s largest glacier; a complex system of ice domes sending down mighty ice streams into the valleys on all sides, often in tremendous icefalls. According to measurements the ice in some places is more than 600 m thick.