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Coronary Heart Disease. Coronary heart disease (CHD), also called coronary artery disease, occurs when plaque builds up in the coronary arteries. These arteries supply oxygen-rich blood to your heart. Plaque narrows the coronary arteries and reduces blood flow to your heart muscle. Plaque buildup also makes it more likely that blood clots will form in your arteries. Blood clots can partially or completely block blood flow.
The coronary arteries regulate the supply of blood to your heart muscle depending on how much oxygen your heart needs at the time, as indicated by: 1  The number of times your heart beats per minute (heart rate). 2  Your blood pressure. 3  The force of your heart's contractions. 4  The thickness of your heart muscle.