Doctors don't know what causes Paget's disease of the breast. The most widely accepted theory is that the disease results from an underlying ductal breast cancer. The cancer cells from the original tumor then travel through milk ducts to the nipple and its surrounding skin.
Glucose in the bloodstream provides the primary fuel for all body tissues. Blood glucose levels are highest during the digestive period after a meal. Your blood sugar is lowest when the stomach and intestines are empty. Under normal circumstances, the body tightly controls the amount of insulin in your blood. An organ called the pancreas, which is tucked behind the stomach releases the hormones insulin and glucagon to regulate blood sugar levels.
Glucagon is secreted to maintain glucose levels in the bloodstream when fasting and to raise very low glucose levels. Glucagon is a hormone that is involved in controlling blood sugar (glucose) levels. It is secreted into the bloodstream by the alpha cells, found in the islets of Langerhans, in the pancreas. The glucagon-secreting alpha cells surround a core of insulin-secreting beta cells, which reflects the close relationship between the two hormones.