Confidence votes 11. According to Wikipedia, the width of the Atlantic Ocean at its narrowest point is 2,848 kilometers (1,770 mi) between Brazil and Sierra Leone.
What causes PNH? It is not fully understood why people develop PNH. Inside the bone marrow, blood cells are made by stem cells (the seed cells of the marrow). PNH occurs due to a change (or mutation) in a gene in one of the stem cells in the bone marrow. This mutation happens in a gene called PIG-A and the cells made by this stem cell lack certain proteins on their surface making them âweakerâ than normal blood cells.
Although it is not yet fully known what causes PNH, all. patients areless able to produce blood cells. They also have. abnormal red blood cells that may be destroyed by their. immune system. PNH is a disor der that affects men and women. of all races, backgrounds, and ages.