Melania Trump. Melania Trump (born Melanija Knavs [mÉËlaËnija ËknaËuÌ¯s], April 26, 1970; Germanized to Melania Knauss) is the First Lady of the United States, married to President Donald Trump.
Rectal administration uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels, and flow into the body's circulatory system, which distributes the drug to the body's organs and bodily systems.n addition, the rectal route bypasses around two thirds of the first-pass metabolism as the rectum's venous drainage is two thirds systemic (middle and inferior rectal vein) and one third portal (superior rectal vein).
Routes of administration. background. The route of administration is defined as the path by which a drug or other substance enters the body. The pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, of a drug are critically influenced by the route of administration.