President Hooverâs inactivity and belief in waiting things out left the United States in economic turmoil and in search of a new more dynamic leader. That leader was Franklin Delano Roosevelt who took over the presidency on January 20, 1933.
The mechanism of diltiazem hepatotoxicity is not known, but most cases are probably due to hypersensitivity. Diltiazem is metabolized by the cytochrome P450 system and is an inhibitor of CYP 3A4 activity, which can lead to serious drug-drug interactions and potentiation of the hepatotoxic effects of other medications.
Diltiazem injection is used to treat irregular heartbeats. OTHER USES: This medication may also be used for chest pain (angina) or high blood pressure. HOW TO USE: This medication is given by vein (slow IV injection or continuous infusion) as directed by the doctor. The patient's blood pressure and heart rhythm (ECG) should be monitored during the administration period.