The evening before the test, 4 tablets are taken with 8 ounces of a clear liquid every 15 minutes for a total of 5 doses (20 tablets total). The next morning, about 3 to 5 hours before the test, another 3 doses of 4 tablets are taken at 15 minute intervals (12 tablets total).
Cerebral malaria. In rare cases, malaria can affect the brain. This is known as cerebral malaria and it can cause your brain to swell, sometimes leading to permanent brain damage. It can also cause seizures (fits) or coma (a state of unconsciousness).
Infection with P. falciparum may result in cerebral malaria, a form of severe malaria that involves encephalopathy. It is associated with retinal whitening, which may be a useful clinical sign in distinguishing malaria from other causes of fever.