1 1902 Willis Haviland Carrier invented the first air conditioner to control the temperature and humidity of a printing company, marking the first time effort taken to control the temperature of the surroundings. 2  This starts the history of air conditioning.
Following the introduction and widespread use of central venous catheters (CVCs) in adult patients, these devices are now frequently used also in the pediatric population. They have become an indispensable route for venous access, especially in pediatric intensive care units (PICUs).
The device that poses the greatest risk for BSI is the central venous catheter (CVC), also known as a central line. It is estimated that more than 5 million CVCs are inserted each year; any patient with a central line is at risk of developing a CLABSI, which is associated with increased morbidity, mortality and cost.