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Freebase(0.00 / 0 votes)Rate this definition: Gynecomastia. Gynecomastia is the benign enlargement of breast tissue in males. It may occur transiently in newborns. Half or more of adolescent boys have some breast development during puberty.
Background. Gynecomastia is a benign enlargement of the male breast resulting from a proliferation of the glandular component of the breast (see the image below).Gynecomastia is defined clinically by the presence of a rubbery or firm mass extending concentrically from the nipples.ackground. Gynecomastia is a benign enlargement of the male breast resulting from a proliferation of the glandular component of the breast (see the image below).