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Freebase(0.00 / 0 votes)Rate this definition: Gynecomastia. Gynecomastia is the benign enlargement of breast tissue in males. It may occur transiently in newborns. Half or more of adolescent boys have some breast development during puberty.
Noun[edit] gynecomastia â(countable and uncountable, plural gynecomastias) (American, medicine) Excessive development of breasts in males, resembling the breast development in women.