For thousands of years it was used by the ancient Egyptians as part of religious ceremonies to reach higher levels of consciousness and connect to the Divine. They would steep the Blue Lotus flowers in wine for several weeks and use it as a sacred sacrament.
1 Metabolic disease. 2  Rare metabolic diseases, such as Wilson's disease and acute fatty liver of pregnancy, infrequently cause acute liver failure. 3  Cancer. 4  Cancer that either begins in or spreads to your liver can cause your liver to fail.
Overdose can cause fatal liver failure. Up to 10% of hospitalisations for overdose and 40% of acute hepatic failure is linked to acetaminophen overdose, which is more often accidental (e.g., children, alcoholics) than intentional (i.e., suicidal). Doses of > 150 mg/kg/24 hours will cause acute liver failure.