1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
1 Traumatic injury or accidents can be the cause of swollen, painful knuckles. 2  When the cartilage becomes damaged, it causes the knuckles to swell. 3  Arthritis is also a common cause of painful swollen, knuckles.ere are some causes of painful swollen knuckles: 1  Traumatic injury or accidents can be the cause of swollen, painful knuckles. 2  When the cartilage becomes damaged, it causes the knuckles to swell. 3  Arthritis is also a common cause of painful swollen, knuckles.