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Freebase(0.00 / 0 votes)Rate this definition: Gynecomastia. Gynecomastia is the benign enlargement of breast tissue in males. It may occur transiently in newborns. Half or more of adolescent boys have some breast development during puberty.
[âgÄ«nÂ·ÉÂ·kÅâ²masÂ·tÄÂ·É] (medicine) Abnormal enlargement of the mammary glands in the male. excessive unilateral or bilateral enlargement of the mammary glands in males, so that they sometimes resemble female glands. Temporary, mild gynecomastia often occurs in adolescent males. Pronounced gynecomastia is one of the symptoms of primary diseases of the endocrine glands, especially the gonads.