A. corner of the patient's mouth to the tip of the earlobe. A. upside down, with the tip toward the roof of the mouth, then flipped 180 degrees over the tongue. B. right side up, using a tongue depressor to press the tongue down and forward to keep it from obstructing the airway.
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to communicate, resulting in a range of signs and symptoms, including physical, mental, and sometimes psychiatric problems.
[journals.plos.org] However, frontal lobe atrophy with white matter lesions associated with cognitive dysfunction may be a part of SCA10 pathology at a late stage of the disease.[journals.plos.org] Spinocerebellar Ataxia Type 19. Certainly, frontal lobe atrophy with white matter lesions in our case was not reported previously in cases with SCA10. [journals.plos.org] Although the primary pathology in SCA10 in humans is reportedly the loss of Purkinje cells, brain MRI revealed frontal lobe atrophy with white matter lesions.