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There are two main strategies for the induction of transcription: a strong promoter is negatively controlled by a repressor protein and induction of transcription is effected by an inducer (a ligand that inactivates the repressor).
RNA polymerases bind to regions of DNA known as promoters. Promoter regions are comprised of the initiation site and numerous nucleotides upstream from the initiation site. The TATA box is necessary for transcription because RNA polymersase II cannot recognize the initiation sites on its own. The TATA box acts as a binding site for some transcription factors, such as TATA binding protein, and is crucial in transcription factors binding the correct part of DNA to start gene transcription. It is also believed to be crucial in RNA Polymerase II binding of DNA. 10 people found this useful.