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CVS is usually performed between 10 and 13 weeks from your last menstrual period. CVS may be chosen over amniocentesis because it may be performed earlier in the pregnancy. Chorionic villus sampling detects chromosome abnormalities (i.e. Down syndrome) and genetic disorders (i.e. cystic fibrosis.).
Thus, thearrangements for supervision should be detailed and justified in the trialproposal and the MRC should satisfy itself that these are appropriate inthe light of the risks involved.When TSCs and DMECs are appropriate: 19985MRC GUIDELINES FOR GOOD CLINICAL PRACTICE IN CLINICAL TRIALS 1998.his is the responsibility of the Principal Investigator, who should ensure that these records are retainedfor the period agreed by the MRC. MRC GUIDELINES FOR GOOD CLINICAL PRACTICE IN CLINICAL TRIALS 199828 8.