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Freebase(0.00 / 0 votes)Rate this definition: Gynecomastia. Gynecomastia is the benign enlargement of breast tissue in males. It may occur transiently in newborns. Half or more of adolescent boys have some breast development during puberty.
U.S. National Library of Medicine (0.00 / 0 votes) Rate this definition: Gynecomastia. Enlargement of the BREAST in the males, caused by an excess of ESTROGENS. Physiological gynecomastia is normally observed in NEWBORNS; ADOLESCENT; and AGING males.