Peter Drier, a bank technology manager in New York City, was blindsided after neck surgery by a $117,000 bill from a doctor he did not recall meeting. Credit Joshua Bright for The New York Times.
Cushing's triad, which includes bradycardia, hypertension (with widened pulse pressure), and a change in respiratory pattern, is seen in head injuries with increased intracranial pressure (ICP).
Iatrogenic Cushing Syndrome - Pathophysiology. 1  Glucocorticoidsâ bioavailability is between 60% and 100%. More than 90% of the circulating glucocorticoid binds to corticosteroid binding globulin (CBG).The unbound free hormone in the circulation binds to the glucocorticoid receptor (GR).