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Hypercoagulable state: A hypercoagulable state is the medical term for a condition in which there is an abnormally increased tendency toward blood clotting (coagulation). There are numerous hypercoagulable states.
Among the factors that may indicate a primary hypercoagulable state are a family history of thrombosis, recurrent thrombosis without apparent precipitating factors, thrombosis at unusual anatomic sites, thrombosis at an early age, and resistance to conventional antithrombotic therapy.