Ono Pharmaceuticals, Opdivo âs originator, has negotiated a price of Â¥150,200 ($1,459) per 20mg vial of Opvido, and Â¥729,849 for 100mg.pplying a similar mark-up to Opdivo, as well as accounting for the higher average body weight of 75kg in the US, gives a price for Opdivo of $118,000 per patient per year, if the same assumption is made about time on therapy.
*Philosophes did not support democracy. -George III of England (r. 1760-1820) and Louis XV of France (r. 1715-1774) had no interest in enlightened monarchy. -Catherine the Great of Russia, Frederick the Great of Prussia, and Joseph II of Austria were Europe's best-known enlightened despots.
despot (ËdÉspÉt) n 1. (Government, Politics & Diplomacy) an absolute or tyrannical ruler; autocrat or tyrant 2. any person in power who acts tyrannically 3. (Historical Terms) a title borne by numerous persons of rank in the later Roman, Byzantine, and Ottoman Empires: the despot of Servia. desâ¢pot (ËdÉs pÉt, -pÉt) n. 1. a king or other ruler with absolute, unlimited power; autocrat. 2. any tyrant or oppressor. 3. a title applied to a Byzantine emperor, and later to Byzantine vassal rulers and governors.