1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
Several conditions can cause nodules to develop in your thyroid gland: 1  Iodine deficiency. 2  Lack of iodine in your diet can sometimes cause your thyroid gland to develop thyroid nodules. 3  But iodine deficiency is uncommon in the United States, where iodine is routinely added to table salt and other foods. Goiter is a term used to describe any enlargement of the thyroid gland, which can be caused by iodine deficiency or a thyroid disorder. 2  A multinodular goiter contains multiple distinct nodules within the goiter, but its cause is less clear.