In Pictures: Americaâs Safest Cities. Henderson, Nev., takes the No. 2 spot despite its location within the Metropolitan Statistical Area of Las Vegas-Paradise, which ranked ninth this year on Forbesâ list of Americaâs Most Dangerous Cities.
Use in Cancer. Recombinant human papillomavirus (HPV) quadrivalent vaccine is approved to prevent some conditions caused by certain types of HPV. It is used in males or females aged 9 to 26 years to prevent the following: 1  Anal cancer.2  Cervical cancer. 3  Vaginal cancer.4  Vulvar cancer.ecombinant human papillomavirus (HPV) quadrivalent vaccine is approved to prevent some conditions caused by certain types of HPV. It is used in males or females aged 9 to 26 years to prevent the following: 1  Anal cancer. 2  Cervical cancer. 3  Vaginal cancer. 4  Vulvar cancer.
In the case of a pandemic, an additional vaccine may be created to protect against a particularly virulent or widespread strain of influenza. The need for a 2009 H1N1 influenza vaccine became apparent after the strains for the seasonal flu vaccine had already been selected, so that a separate vaccine was created. A quadrivalent inactivated influenza vaccine was licensed in the United States in 2012, and a quadrivalent live virus nasal spray vaccine was licensed in 2013. These formulations include two influenza B strains in addition to the A strains. This vaccines began to be available, along with trivalent vaccines, in the 2013-14 influenza season.