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Biochemistry of Dog Coat Color. The color of a dogâs coat is determined by relative levels of two pigments: eumelanin, which can be either brown or black, and pheomelanin, which is yellow to orange or red. Both pigments are generated by metabolism of tyrosine. A schematic diagram of the pathway is below. Schematic of the melanin synthesis pathways.
In some cases we can break down a trait into a specific combination of genes. In the case of color, for instance, we know of a considerable number of genes that affect color through specific processes. In some cases, this knowledge has fed back on what we consider to be traits. Thus in the case given, the dog is: Sable Ay_ (as opposed to black with or without tan-point markings).