But a state with two excellent universities has that - not two flagships. Flagship is a singular term - a good reference for the word generally can be found here. In this context, flagship means, as the introduction says, the leading comprehensive public research university in a given U.S. state.
During any pregnancy a small amount of the baby's blood can enter the mother's circulation. If the mother is Rh negative and the baby is Rh positive, the mother produces antibodies (including IgG) against the Rhesus D antigen on her baby's red blood cells.
In this case, the most likely explanation is that dad is a carrier for being Rh- and mom is a carrier for blood type O. What happened was that dad and mom each passed both an O and an Rh negative to the baby. The end result is an O negative child.