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Hypercoagulable state: A hypercoagulable state is the medical term for a condition in which there is an abnormally increased tendency toward blood clotting (coagulation). There are numerous hypercoagulable states.
Hypercoagulation. Hypercoagulation or a hypercoagulable state results in a tendency to form thrombus. Blood flow problems and changes in blood vessel walls can cause platelets to gather or aggregate and adhere to vessel walls, initiating a pathophysiological clotting process.