Project Narrative. 2 to 3 sentences maximum. For NIH and other PHS agencies applications, this attachment will reflect the second component of the Project Summary: Relevance. Using no more than two or three sentences, describe the relevance of this research to public health. In this section, be succinct and use plain language that can be understood by a general, lay audience. A separate Research Plan component is required for NIH and other PHS agencies applications.
Methadone is a powerful narcotic. It can cause some people to feel drowsy, dizzy, or light-headed. People taking methadone should not drive a car or operate machinery. Intentional or accidental overdose of methadone can lead to unconsciousness, coma, or death.
Methadone effects on the body and brain. Methadone is a prescription drug used to treat opiate addiction and dependence and/or for the relief of moderate to severe pain. Effects are mediated by opioid receptors in the central nervous system as methadone affects neurotransmission.urther, methadone is a synthetic narcotic and belongs under the Schedule ll of DEA controlled substances. As a prescribed medication, methadone is available in the form of tablets of 5-10mg, dispersible tablets 40 mg, oral solutions 1-2 mg/mL strength or injectable solutions of 10 mg/mL.