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Thrombophilia (sometimes hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels).
What Is Excessive Blood Clotting (Hypercoagulation)? Updated:Nov 30,2015. When you get a cut or wound, your body forms blood clots, a thickened mass of blood tissue, to help stop the bleeding. Proteins in your blood called fibrins work with small blood cell fragments called platelets, to form the clot.