Confidence votes 11. According to Wikipedia, the width of the Atlantic Ocean at its narrowest point is 2,848 kilometers (1,770 mi) between Brazil and Sierra Leone.
Paroxysmal nocturnal hemoglobinuria (PNH) definition and facts. PNH is a rare, chronic disease that causes rapid breakdown of red blood cells and can result in reddish or cola-colored urine, often seen in the early morning after urination. PNH is due to a spontaneous mutation in gene material. PNH is not inherited.
Classical PKU is caused by a deficiency of the enzyme phenylalanine hydroxylase (PAH). Over 70 different mutations on the PAH gene found on Chromosome 12 have been found to cause the almost complete absence of PAH as seen in PKU patients.revalence. The incidence of PKU is highly variable in different populations. Many PAH gene mutations are thought to be Celtic in origin, this is supported by high frequencies of PKU in the Irish and in the Scottish, and for example an incidence of 1/4500 is seen in the Irish.