A dose of 0.5 milligrams of melatonin has been taken under the tongue for six days. For seizure disorders, doses of melatonin taken by mouth were 3-10 milligrams daily for 2-4 weeks to three months. For sleep (general), doses of melatonin taken by mouth were 0.3-10 milligrams.
The degradation of the synthetic, amphoteric surfactant, cocamidopropyl betaine (CAPB) and its toxicity to the marine macroalga, Ulva lactuca, has been evaluated using several different physiological test end-points over different periods of exposure up to 120 h.ell membrane damage, estimated from measurements of ion leakage, was detected only at a concentration of 40 mg l(-1) after 48 h of exposure to CAPB but by 120 h damage was evident at all measured concentrations above 10 mg l(-1).
Lead (II) sulfate is also partially soluble in diluted hydrogen chloride and nitric acid. It is soluble in sodium hydroxide and ammonium acetate. Lead (II) sulfate, like all lead compounds, is toxic to humans. It is readily absorbed by the skin and can cause injury to the central nervous system and birth defects. Ingesting large quantities of lead (II) sulfate can cause seizures, coma and even death.