A dose of 0.5 milligrams of melatonin has been taken under the tongue for six days. For seizure disorders, doses of melatonin taken by mouth were 3-10 milligrams daily for 2-4 weeks to three months. For sleep (general), doses of melatonin taken by mouth were 0.3-10 milligrams.
The degradation of the synthetic, amphoteric surfactant, cocamidopropyl betaine (CAPB) and its toxicity to the marine macroalga, Ulva lactuca, has been evaluated using several different physiological test end-points over different periods of exposure up to 120 h.ell membrane damage, estimated from measurements of ion leakage, was detected only at a concentration of 40 mg l(-1) after 48 h of exposure to CAPB but by 120 h damage was evident at all measured concentrations above 10 mg l(-1).
Abrin is a highly toxic toxalbumin found in the seeds of the rosary pea (jequirity pea). It has a median toxic dose of 0.7 micrograms per kilogram of body mass when given to mice intravenously (approximately 31.4 times more toxic than ricin being 22 micrograms per kilogram).he median toxic dose for humans ranges from 10 to 1000 micrograms per kilogram when ingested and is 3.3 micrograms per kilogram when inhaled. Abrin, like ricin, is a ribosome inhibiting protein and the toxin can also be found in the seeds of the castor oil plant.