1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
Knuckle cracking has not been shown to be harmful or beneficial. More specifically, knuckle cracking does not cause arthritis. Joint cracking can result from a negative pressure pulling nitrogen gas temporarily into the joint, such as when knuckles are cracked.. This is not harmful.