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Quick Answer. Hiccups resulting from surgery may be caused by a reaction to anesthesia or happen as a result of abdominal surgery or medical procedures such as a tracheotomy, states Healthline. Using a catheter to access the heart, bronchoscopy or using a stent in the esophagus can also result in long-term hiccups.
A large number of medications may cause hiccups. Medications taken only at bedtime, such as sleep medicine, cause hiccups primarily during sleep. Other medications cause hiccups at other times of the day as well. These are examples of medications that may produce hiccups: Sleep medications: eszopiclone (Lunesta)