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Watson and Crick describe structure of DNA1953. Photo: Model of DNA molecule. In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases.Later it was found that the sugar in nucleic acid can be ribose or deoxyribose, giving two forms: RNA and DNA.atson and Crick describe structure of DNA1953. Photo: Model of DNA molecule. In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases.
The monomers from which nucleic acids are constructed are called nucleotides. Each nucleotide consists of three components: a nitrogenous heterocyclic base, either a purine or a pyrimidine; a pentose sugar; and a phosphate group.Different nucleic acid types differ in the structure of the sugar in their nucleotides; DNA contains 2-deoxyriboses while RNA contains ribose.how more I know that nucleic acids are made up of nucleotides, and nucleotides are made up of a nitrogenous base, a sugar (either ribose for RNA or deoxyribose for DNA), and a phosphate group.