Optic disc drusen are abnormal deposits of protein-like material in the optic disc â the front part of the optic nerve. We do not know the exact cause of optic disc drusen but they are thought to come from abnormal flow of material in optic nerve cells.ptic Disc Drusen, Page 3 optic nerve from increased intracranial pressure. This prompts referral to a neurologist, neuro-surgeon, or even the emergency room. Diagnosis Optic disc drusen either can be buried within the substance of the optic nerve head or located superficially on the surface of the optic nerve head.
The Hagia Sophia was constructed in five years, from 532 to 537, at the orders of Emperor Justinian I and designed by Isidore of Miletus. Immediately after the Turks conquered Constantinople (Istanbul) in 1453, the Hagia Sophia was converted to a mosque. In 1935, the first Turkish President and founder of the Republic of Turkey, Mustafa Kemal Atatuerk, atatÃ¼rk transformed the building into a. museum
But it was the dome that made Hagia Sophia the most complex building of antiquity. The shallow dome was made from 40 equally spaced ribs. Forty windows were then set at the dome's base, creating the sensation that the dome actually floated over the church. In 559 A.D., an earthquake tumbled the dome.