Usage Note: Native American is now fully established in American English as an equivalent of Indian, being acceptable in all contemporary contexts and preferred in many. It is especially appropriate as a term of respect used by outsiders, who may have concerns that Indian could cause offense by its association with longstanding cultural stereotypes.
In Basel, Switzerland, Albert Hoffman, a Swiss chemist working at the Sandoz pharmaceutical research laboratory, accidentally consumes LSD-25, a synthetic drug he had created in 1938 as part of his research into the medicinal value of lysergic acid compounds.
LSD stands for  lyserg saeure diaethylamid  in the original German. In English, it is called lysergic acid diethylamide. Dr. Albert Hofmann, a Swiss chemist looking for a new headache treatment, first produced LSD in 1938. He first developed lysergic acid, a derivative of ergot, a fungus that grows on the rye plant. dose the size of a grain of salt can cause effects. LSD inhibits the movement of serotonin in the brain, which influences mood. LSD seems to work in the cerebral cortex of the brain, which is involved in mood, thought, and perception, and in the locus ceruleus of the brain, which coordinates sensory perceptions.