President Hooverâs inactivity and belief in waiting things out left the United States in economic turmoil and in search of a new more dynamic leader. That leader was Franklin Delano Roosevelt who took over the presidency on January 20, 1933.
The mechanism of diltiazem hepatotoxicity is not known, but most cases are probably due to hypersensitivity. Diltiazem is metabolized by the cytochrome P450 system and is an inhibitor of CYP 3A4 activity, which can lead to serious drug-drug interactions and potentiation of the hepatotoxic effects of other medications.
Diltiazem. Diltiazem is a prescription medication used for controlling high blood pressure and treating certain types of chest pain. The medication is a type of calcium channel blocker that helps to relax the blood vessels to improve blood flow. Diltiazem hydrochloride is a prescription medication used to treat high blood pressure (hypertension) and certain types of chest pain (angina). (Click Diltiazem Uses for more information on what it is used for, including possible off-label uses.)