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Watson and Crick describe structure of DNA1953. Photo: Model of DNA molecule. In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases.Later it was found that the sugar in nucleic acid can be ribose or deoxyribose, giving two forms: RNA and DNA.atson and Crick describe structure of DNA1953. Photo: Model of DNA molecule. In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases.
A nucleotide is made up of a sugar (deoxyribose in DNA and ribose in RNA), a phosphate and a nitrogenous base. The nitrogenous bases found in DNA are adenine (A), thymine (T â¦), cytosine (C) and guanine (G).he three components that make up the nucleotides of RNA are the nucleobases, the ribose sugars, and the phosphate backbone. The nucleobases are what give RNA its variability, â¦ denoted by the letters A, C, G and U. They form the alphabet that gets translated into the different amino acids that make up proteins.