The Baroque was an elaborate style of art that existed in Europe from the late 1500s to the middle 1700s. Baroque paintings, sculptures, and buildings, as well as musical compositions, are known for their richness and drama. The grand works of art were meant to appeal to a personâs emotions or senses.
Dopamine Levels Increase. All addictive drugs affect brain pathways involving rewardâthat is, the dopamine system in the reward pathway. Within seconds to minutes of entering the body, drugs cause dramatic changes to synapses in the brain. By activating the brain's reward circuitry, drugs deliver a jolt of intense pleasure.
Cocaine has its major effect by blocking the re-uptake of the neurotransmitters Dopamine and Serotonin. Opioid drugs bind to special endorphin receptors in the brain (the 'mu', 'kappa', 'sigma' 'delta' and 'gamma' receptors) that have to do with pain.