1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
Osteoarthritis causes cartilage-- a tough but flexible tissue that covers the ends of the bones forming a joint -- to wear away gradually. Thumb osteoarthritis most commonly affects the joint at the base of the thumb, also known as the basal joint or the carpometacarpal joint (CMC joint). The CMC joint is formed where the metacarpal bone of the thumb attaches to the trapezium bone of the wrist.