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Biochemistry of Dog Coat Color. The color of a dogâs coat is determined by relative levels of two pigments: eumelanin, which can be either brown or black, and pheomelanin, which is yellow to orange or red. Both pigments are generated by metabolism of tyrosine. A schematic diagram of the pathway is below. Schematic of the melanin synthesis pathways.
Coat color and pattern is a polygenic trait, meaning it is controlled by more than one gene or gene complex.A dog with the gene for black color expression may also have the gene for suppression of black and so have a red or yellow coat. Polygenic traits are [characteristics of organisms that are] â¦  influenced by several genes.    So multiple alleles are more than two alleles for one trait, and  polygenic traits are one trait that is influenced by mulitple  genes.