PHOTOS: Stars who have never won an Oscar. Most film nominations without a win: The Turning Point (1977) and The Color Purple (1985), with 11 nominations each. Most acting nominations without a competitive win: Peter O'Toole, with 8 nominations (O'Toole later won an Honorary Oscar in 2003).
An autoimmune disease is a condition in which your immune system mistakenly attacks your body. The immune system normally guards against germs like bacteria and viruses. When it senses these foreign invaders, it sends out an army of fighter cells to attack them.
Autoimmunity: A misdirected immune response that occurs when the immune system goes awry and attacks the body itself. Autoimmunity is present to some extent in everyone and is usually harmless. However, autoimmunity can cause a broad range of human illnesses, known collectively as autoimmune diseases. Autoimmune diseases occur when there is progression from benign autoimmunity to pathogenic autoimmunity.