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Watson and Crick describe structure of DNA1953. Photo: Model of DNA molecule. In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases.Later it was found that the sugar in nucleic acid can be ribose or deoxyribose, giving two forms: RNA and DNA.atson and Crick describe structure of DNA1953. Photo: Model of DNA molecule. In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases.
Nucleotides. the basic units of nucleic acids. Some nucleotides are coenzymes or other biologically active compounds. Each nucleotide is composed of a nitrogenous base, usually purine or pyrimidine; a carbohydrate, either ribose or deoxyribose; and a phosphoric acid residue.ucleotides with three phosphoric acid residuesânucleoside triphosphatesâare high-energy compounds; these are the direct precursors in the biosynthesis of nucleic acids.