Confidence votes 11. According to Wikipedia, the width of the Atlantic Ocean at its narrowest point is 2,848 kilometers (1,770 mi) between Brazil and Sierra Leone.
Paroxysmal nocturnal hemoglobinuria or PNH is a rare and chronic disease that results in an abnormal breakdown of red blood cells. PNH is due to a spontaneous genetic mutation that causes red blood cells to be deficient in a protein, leaving them fragile.
Causes of PNH. PNH happens because of a change (mutation) in the PIG-A gene of a single stem cell in your bone marrow. This gene controls the creation of substance that helps certain proteins to stick to blood cells. Therefore, any blood cells created by this mutant bone marrow stem cell are abnormal.