1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
The majority of thyroid nodules are an overgrowth of normal thyroid tissue. What causes the overgrowth of tissue is not known. Nodules are often found in people who have Hashimotoâs disease, an autoimmune disease that leads to hypothyroidism.