PHOTOS: Stars who have never won an Oscar. Most film nominations without a win: The Turning Point (1977) and The Color Purple (1985), with 11 nominations each. Most acting nominations without a competitive win: Peter O'Toole, with 8 nominations (O'Toole later won an Honorary Oscar in 2003).
An autoimmune disease is a condition in which your immune system mistakenly attacks your body. The immune system normally guards against germs like bacteria and viruses. When it senses these foreign invaders, it sends out an army of fighter cells to attack them.
In an autoimmune disease, the immune system mistakes part of your body â like your joints or skin â as foreign. It releases proteins called autoantibodies that attack healthy cells. Some autoimmune diseases target only one organ. Type 1 diabetes damages the pancreas. Other diseases, like lupus, affect the whole body.