Often, for gene transcription to occur, a number of transcription factors must bind to DNA regulatory sequences. This collection of transcription factors, in turn, recruit intermediary proteins such as cofactors that allow efficient recruitment of the preinitiation complex and RNA polymerase.ranscription factors use a variety of mechanisms for the regulation of gene expression. These mechanisms include: 1  stabilize or block the binding of RNA polymerase to DNA. 2  catalyze the acetylation or deacetylation of histone proteins.
The best time to take this, and other statin anti-cholesterol meds, is about 6pm in the evening. This has nothing to do with meals. Rather, it's best to get the drug in your â¦ system when cholesterol is being made in the body by the liver, which occurs between 6pm and midnight.+ 3 others found this useful.he best time to take this, and other statin anti-cholesterol meds, is about 6pm in the evening. This has nothing to do with meals. Rather, it's best to get the drug in your â¦ system when cholesterol is being made in the body by the liver, which occurs between 6pm and midnight. + 3 others found this useful.
For long-term management, a maintenance dose of one gastro-resistant tablet Pantoprazole 20 mg per day is recommended, increasing to 40 mg pantoprazole per day if a relapse occurs. Pantoprazole 40 mg is available for this case.After healing of the relapse the dose can be reduced again to 20 mg pantoprazole.dults and adolescents 12 years of age and above. The recommended oral dosage is one gastro-resistant tablet Pantoprazole 20 mg per day. Symptom relief is generally accomplished within 2-4 weeks. If this is not sufficient, symptom relief will normally be achieved within a further 4 weeks.