Confidence votes 11. According to Wikipedia, the width of the Atlantic Ocean at its narrowest point is 2,848 kilometers (1,770 mi) between Brazil and Sierra Leone.
Paroxysmal nocturnal hemoglobinuria or PNH is a rare and chronic disease that results in an abnormal breakdown of red blood cells. PNH is due to a spontaneous genetic mutation that causes red blood cells to be deficient in a protein, leaving them fragile.
Hemolysis is the main cause of the signs, symptoms, and serious health problems in PNH, including some that are life-threatening. 1  Hemolysis is the destruction of red blood cellsA type of cell found in your blood that delivers oxygen and removes waste (carbon dioxide) in your body.t can also lead to signs and symptoms like 2,4 1  : FatigueTiredness, trouble concentrating, dizziness, and weakness to the point where even normal, everyday activities become a struggle. 2  In PNH, fatigue is often out of proportion to the amount of anemia, as measured by hemoglobin, because it is affected by hemolysis.