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1 A biologic is manufactured in a living system such as a microorganism, or plant or animal cells. 2  Most biologics are very large, complex molecules or mixtures of molecules.
From Wikipedia, the free encyclopedia. A biopharmaceutical, also known as a biologic medical product or biologic, is any medicinal product manufactured in, extracted from, or semisynthesized from biological sources.n the European Union, a biological medicinal product is one of the active substance(s) produced from or extracted from a biological (living) system, and requires, in addition to physico-chemical testing, biological testing for full characterisation.