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Creatinine is a metabolic by-product of muscle metabolism, and normally appears in urine in relatively constant quantities over a 24 hour period with normal liquid intake. Therefore, urine creatinine can be used as an indicator of urine water content or as a marker identifying a specimen as urine. Greater than normal intake of water will increase the urine water content (lowering the creatinine level) consequently diluting the amount of drug in urine. Conversely, a limited intake of water can lead to an abnormally concentrated urine specimen (as occurs with dehydration) resulting in elevated creatinine levels.
This urine test measures very small amounts of a protein called albumin. Your liver makes albumin and your body uses it to grow and repair tissues and to help your body get rid of extra fluid. Another test to check the level of a substance called creatinine in the urine is usually done at the same time. Then the ratio of albumin to creatinine is reported. Creatinine is one of the waste chemicals in the blood that the kidney filters into the urine. This test is done to check for early signs of kidney damage, especially if you have diabetes. The kidneys are inside your belly, on either side of your spine just above your waist.