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1 A biologic is manufactured in a living system such as a microorganism, or plant or animal cells. 2  Most biologics are very large, complex molecules or mixtures of molecules.
1 Most biologics are very large, complex molecules or mixtures of molecules. Many biologics are produced using recombinant DNA technology.  A drug is typically manufactured through chemical synthesis, which means that it is made by combining specific chemical ingredients in an ordered process.