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There are two main strategies for the induction of transcription: a strong promoter is negatively controlled by a repressor protein and induction of transcription is effected by an inducer (a ligand that inactivates the repressor).
Lac repressor occurs in two conformations. In the absence of inducer, it binds tightly to lac operator DNA and thus represses transcription from the adjacent lac promoter. In the presence of inducer, it changes its conformation and binds about 1000-fold less tightly to lac operator.