1 VICODIN, VICODIN ES, and VICODIN HP should not be used if you are allergic to hydrocodone or acetaminophen. 2  Tell your healthcare provider if you are allergic to any other opioid pain medicine before taking this drug, as you may exhibit cross-sensitivity to hydrocodone.
Stiffness is generally worse with repeated use and better with rest. Heberden nodes are small, red nodules that occur at the last joint of the finger. They may deform the joint, creating the knobby knuckles and twisted fingers of severe OA.
Common causes of ridges on nails. Nails are comprised of Keratin (protein) a tough substance that protects the end of each finger and toe. The following is a list of possible causes as to why vertical ridges may appear on the nails: 1  It is traditionally believed that ridge formation on the nails relates to a possible weakness in the digestive tract that results in compromised assimilation of nutrients (leaky gut, allergies, food sensitivities, maldigestion)