Optic disc drusen are abnormal deposits of protein-like material in the optic disc â the front part of the optic nerve. We do not know the exact cause of optic disc drusen but they are thought to come from abnormal flow of material in optic nerve cells.ptic Disc Drusen, Page 3 optic nerve from increased intracranial pressure. This prompts referral to a neurologist, neuro-surgeon, or even the emergency room. Diagnosis Optic disc drusen either can be buried within the substance of the optic nerve head or located superficially on the surface of the optic nerve head.
The Hagia Sophia was constructed in five years, from 532 to 537, at the orders of Emperor Justinian I and designed by Isidore of Miletus. Immediately after the Turks conquered Constantinople (Istanbul) in 1453, the Hagia Sophia was converted to a mosque. In 1935, the first Turkish President and founder of the Republic of Turkey, Mustafa Kemal Atatuerk, atatÃ¼rk transformed the building into a. museum
Byzantium; in medieval Russian texts, Tsarâgrad; capital of the Roman Empire from. 330 and later of the Byzantine Empire. Constantinople was founded by the Roman emperor Constantine I in 324â330 on the site of the city of Byzantium on the European shore of the Bosporus.he city became the capital of the Latin Empire created by the Crusaders in 1204; economic primacy within it went to the Venetians. In July 1261, the Byzantines, with the assistance of the Genoese, won back Constantinople.