Hyponyms (each of the following is a kind of lacrimator): chlorobenzylidenemalononitrile; CS gas (a tear gas that is stronger than CN gas but wears off faster; can be deployed by grenades or cluster bombs; can cause skin burns and fatal pulmonary edema)
Freebase(0.00 / 0 votes)Rate this definition: Renin. Renin, also known as an angiotensinogenase, is an enzyme that participates in the body's renin-angiotensin system âalso known as the renin-angiotensin-aldosterone axisâthat mediates extracellular volume, and arterial vasoconstriction.
Renin inhibitors are a group of pharmaceutical drugs used primarily in treatment of essential hypertension. These drugs inhibit the first and rate-limiting step of the reninâangiotensinâaldosterone system, namely the conversion of angiotensinogen to angiotensin I. This leads to a totality in absence of Angiotensin II based on the rationale that renin only acts to inhibit this step unlike Angiotensin Converting Enzyme which is also involved in other biochemical reactions. Since the 1970s ...