An archive is an accumulation of historical records or the physical place they are located.[1] Archives contain primary source documents that have accumulated over the course of an individual or organization's lifetime, and are kept to show the function of that person or organization.
Pfeiffer syndrome is a complex genetic disorder that affects your childâs head, face, hands and feet. Clinical features vary for different children and range from mild to severe. Craniosynostosis: Premature (early) closure of growth plates of the skull that changes the shape of the head and can put increased pressure on the brain.
Abstract. 1  Pfeiffer syndrome is a rare autosomal dominantly inherited disorder that associates craniosynostosis, broad and deviated thumbs and big toes, and partial syndactyly on hands and feet. Hydrocephaly may be found occasionally, along with severe ocular proptosis, ankylosed elbows, abnormal viscera, and slow development.