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1 A biologic is manufactured in a living system such as a microorganism, or plant or animal cells. 2  Most biologics are very large, complex molecules or mixtures of molecules.
Medicines called biologics may be used to treat severe psoriasis or psoriasis that hasn't improved after other treatments. Biologics are similar to or the same as proteins made by the body. These medicines block the harmful response of the body's immune system that causes the symptoms of psoriasis.