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Watson and Crick describe structure of DNA1953. Photo: Model of DNA molecule. In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases.Later it was found that the sugar in nucleic acid can be ribose or deoxyribose, giving two forms: RNA and DNA.atson and Crick describe structure of DNA1953. Photo: Model of DNA molecule. In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases.
    The nucleotides which make up nucleic acids are composed of the following: a phosphate group (PO4), a deoxyribose sugar (in DNA) or a ribose sugar (in RNA) and finally a nitrogenous base.     In DNA the purine nitrogenous bases are: adenine and guanine.