Diseases that cause Hyper-excitability. Peripheral nerve hyperexcitability (PNH) is any disorders associated with twitching spasms, spontaneous muscular activities, facial tics etc.iseases that cause Hyper-excitability. Peripheral nerve hyperexcitability (PNH) is any disorders associated with twitching spasms, spontaneous muscular activities, facial tics etc.
On April 6, 1652 the first white people (Dutch) arrived in South Africa to establish a settlement at the Cape. Their purpose, initially, was not to colonize the area, but to s â¦ upply fresh food for the men on the Dutch ships sailing on the long route between Europe and India.
The Portuguese as they pushed south along the coast of West Africa were the first Europeans to come into contact with the people of Sub-Saharan Africa. Thus when Portugal and Spain established the first American colonies, they first introduced Africans as a labor source in the New World. It was sugar that first made slavery important and Caribbean sugar islands became enormously important.